1. Comparative compositional analysis of cassava brown streak disease resistant 4046 cassava and its non-transgenic parental cultivar
- Author
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A. Bua, Nigel J. Taylor, A Kiggundu, Henry Wagaba, Ephraim Nuwamanya, B M Zawedde, P Raymond, D J MacKenzie, Titus Alicai, Getu Beyene, Hannington Obiero, J Aleu, P Wangari, C Taracha, Douglas W. Miano, P.K. Kuria, Williams Esuma, and S Gichuki
- Subjects
RNA interference (RNAi) ,Manihot ,Transgene ,Streak ,Biology ,cassava ,genetically engineered ,Animals ,Uganda ,Cultivar ,Disease resistant ,Plant Diseases ,Substantial equivalence ,business.industry ,Genetically engineered ,food and beverages ,Potyviridae ,Plants, Genetically Modified ,Biotechnology ,business ,Agronomy and Crop Science ,substantial equivalence ,Research Article ,Research Paper ,Food Science - Abstract
Compositional analysis is an important component of an integrated comparative approach to assessing the food and feed safety of new crops developed using biotechnology. As part of the safety assessment of cassava brown streak disease resistant 4046 cassava, a comprehensive assessment of proximates, minerals, amino acids, fatty acids, vitamins, anti-nutrients, and secondary metabolites was performed on leaf and storage root samples of 4046 cassava and its non-transgenic parental control, TME 204, collected from confined field trials in Kenya and Uganda over two successive cropping cycles. Among the 100 compositional components that were assessed in samples of 4046 and control TME 204 cassava roots (47 components) and leaves (53 components), there were no nutritionally relevant differences noted. Although there were statistically significant differences between the transgenic and control samples for some parameters, in most cases the magnitudes of these differences were small (
- Published
- 2020
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