Search

Your search keyword '"Ozlu F."' showing total 8 results
Start Over Author "Ozlu F." Database OpenAIRE
8 results on '"Ozlu F."'

1. Comparing Conservative and Medical Management for Patent Ductus

Author

Okulu, E, Erdeve, O, Arslan, Z, Demirel, N, Kaya, H, Gokce, IK, Ertugrul, S, Cetinkaya, M, Buyukkale, G, Ozlu, F, Simsek, H, Celik, Y, Ozkan, H, Koksal, N, Akcan, B, Turkmen, M, Celik, K, Armangil, D, Bulbul, A, Tekgunduz, KS, Oncel, MY, Tuzun, F, Ergenekon, E, Ergin, H, and Arsan, S

Subjects
mortality, ibuprofen, paracetamol, patent ductus arteriosus, preterm, conservative, management, morbidity
Abstract

No consensus has been reached on which patent ductus arteriosus (PDAs) in preterm infants require treatment and if so, how, and when they should be treated. A prospective, multicenter, cohort study was conducted to compare the effects of conservative approaches and medical treatment options on ductal closure at discharge, surgical ligation, prematurity-related morbidities, and mortality. Infants between 24(0/7)and 28(6/7)weeks of gestation from 24 neonatal intensive care units were enrolled. Data on PDA management and patients' clinical characteristics were recorded prospectively. Patients with moderate-to-large PDA were compared. Among the 1,193 enrolled infants (26.7 +/- 1.4 weeks and 926 +/- 243 g), 649 (54%) had no or small PDA, whereas 544 (46%) had moderate-to-large PDA. One hundred thirty (24%) infants with moderate-to-large PDA were managed conservatively, in contrast to 414 (76%) who received medical treatment. Eighty (62%) of 130 infants who were managed conservatively did not receive any rescue treatment and the PDA closure rate was 53% at discharge. There were no differences in the rates of late-onset sepsis, necrotizing enterocolitis (NEC), retinopathy of prematurity, intraventricular hemorrhage (>= Grade 3), surgical ligation, and presence of PDA at discharge between conservatively-managed and medically-treated infants (p> 0.05). Multivariate analysis including perinatal factors showed that medical treatment was associated with increased risk for mortality (OR 1.68, 95% Cl 1.01-2.80,p= 0.046), but decreased risk for BPD or death (BPD/death) (OR 0.59, 95%Cl 0.37-0.92,p= 0.022). The preferred treatment options were ibuprofen (intravenous 36%, oral 31%), and paracetamol (intravenous 26%, oral 7%). Infants who were treated with oral paracetamol had higher rates of NEC and mortality in comparison to other treatment options. Infants treated before postnatal day 7 had higher rates of mortality and BPD/death than infants who were conservatively managed or treated beyond day 7 (p= 0.009 and 0.007, respectively). In preterm infants born at

Published
2020

2. An Observational, prospective, multicenter, registry-based cohort study comparing conservative and medical management for patent ductus arteriosus

Author

Okulu, E., Erdeve, O., Arslan, Z., Demirel, N., Kaya, H., Gokce, I.K., Ertugrul, S., Cetinkaya, M., Buyukkale, G., Ozlu, F., Simsek, H., Celik, Y., Ozkan, H., Köksal, N., Akcan, B., Turkmen, M., Celik, K., Armangil, D., Bulbul, A., Tekgunduz, K.S., Oncel, M.Y., Tuzun, F., Ergenekon, E., Ergin, Hacer, Arsan, S., Turkish Neonatal Society INTERPDA Study Group, Dicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalı, and Ertuğrul, Sabahattin

Subjects
Pediatrics, paracetamol, Patent ductus arteriosus, morbidity, Ibuprofen, 030204 cardiovascular system & hematology, lung dysplasia, assisted ventilation, 0302 clinical medicine, newborn sepsis, Ductus arteriosus, odds ratio, Conservative, gestational age, risk reduction, ibuprofen, steroid, lcsh:RJ1-570, Retinopathy of prematurity, cohort analysis, Clinical Trial, infant mortality, Management, medicine.anatomical_structure, Intraventricular hemorrhage, female, multivariate analysis, Paracetamol, risk factor, Necrotizing enterocolitis, brain hemorrhage, retrolental fibroplasia, Gestation, disease registry, pregnancy, newborn morbidity, artery ligation, management, Cohort study, prospective study, survival rate, medicine.medical_specialty, conservative treatment, surgical technique, Article, Sepsis, 03 medical and health sciences, patent ductus arteriosus, male, Preterm, 030225 pediatrics, Intensive care, medicine, controlled study, human, Mortality, outcome assessment, perinatal period, necrotizing enterocolitis, business.industry, prematurity, lcsh:Pediatrics, medicine.disease, mortality, infant, major clinical study, neonatal intensive care unit, clinical feature, hospital discharge, multicenter study, confidence interval, neonatal respiratory distress syndrome, Pediatrics, Perinatology and Child Health, conservative, observational study, Morbidity, business, preterm, artificial lung surfactant
Abstract

No consensus has been reached on which patent ductus arteriosus (PDAs) in preterm infants require treatment and if so, how, and when they should be treated. A prospective, multicenter, cohort study was conducted to compare the effects of conservative approaches and medical treatment options on ductal closure at discharge, surgical ligation, prematurity-related morbidities, and mortality. Infants between 240/7 and 286/7 weeks of gestation from 24 neonatal intensive care units were enrolled. Data on PDA management and patients' clinical characteristics were recorded prospectively. Patients with moderate-to-large PDA were compared. Among the 1,193 enrolled infants (26.7 ± 1.4 weeks and 926 ± 243 g), 649 (54%) had no or small PDA, whereas 544 (46%) had moderate-to-large PDA. One hundred thirty (24%) infants with moderate-to-large PDA were managed conservatively, in contrast to 414 (76%) who received medical treatment. Eighty (62%) of 130 infants who were managed conservatively did not receive any rescue treatment and the PDA closure rate was 53% at discharge. There were no differences in the rates of late-onset sepsis, necrotizing enterocolitis (NEC), retinopathy of prematurity, intraventricular hemorrhage (?Grade 3), surgical ligation, and presence of PDA at discharge between conservatively-managed and medically-treated infants (p > 0.05). Multivariate analysis including perinatal factors showed that medical treatment was associated with increased risk for mortality (OR 1.68, 95% Cl 1.01–2.80, p = 0.046), but decreased risk for BPD or death (BPD/death) (OR 0.59, 95%Cl 0.37–0.92, p = 0.022). The preferred treatment options were ibuprofen (intravenous 36%, oral 31%), and paracetamol (intravenous 26%, oral 7%). Infants who were treated with oral paracetamol had higher rates of NEC and mortality in comparison to other treatment options. Infants treated before postnatal day 7 had higher rates of mortality and BPD/death than infants who were conservatively managed or treated beyond day 7 (p = 0.009 and 0.007, respectively). In preterm infants born at

Published
2020
Full Text
View/download PDF

3. Early neonatal outcomes of very-low-birth-weight infants in Turkey: A prospective multicenter study of the Turkish Neonatal Society

Author

Koc E, Demirel N, Bas AY, Ulubas Isik DAUID- ORCID: 0000-0001-9937-4624, Hirfanoglu IM, Tunc T, Sari FN, Karatekin G, Ozdemir R, Altunhan H, Cetinkaya M, Ozcan B, Ozkiraz S, Calkavur S, Tekgunduz KS, Tastekin A, Ozlu F, Mutlu Ozyurt B, Ozdemir A, Cetinkaya B, Demirelli Y, Koklu E, Celik U, Tarakci N, Armangil D, Okulu E, Narter F, Mutlu B, Mert MK, Bulbul A, Asker HS, Uygur O, Uslu IS, Ertugrul S, Aydemir C, Celik HT, Kucuktasci K, Arslan S, Ergin H, Zenciroglu A, Yurttutan S, Orman A, and Tuncer O

Subjects
Adult, Birth Weight, Female, Gestational Age, Humans, Infant, Newborn, Infant, Newborn, Diseases/*epidemiology, Infant, Very Low Birth Weight, Intensive Care Units, Neonatal, Male, Morbidity, Pregnancy, Pregnancy Outcome/*epidemiology, Prospective Studies, Turkey/epidemiology
Abstract

OBJECTIVE: To investigate the early neonatal outcomes of very-low-birth-weight (VLBW) infants discharged home from neonatal intensive care units (NICUs) in Turkey. MATERIAL AND METHODS: A prospective cohort study was performed between April 1, 2016 and April 30, 2017. The study included VLBW infants admitted to level III NICUs. Perinatal and neonatal data of all infants born with a birth weight of ≤1500 g were collected for infants who survived. RESULTS: Data from 69 NICUs were obtained. The mean birth weight and gestational age were 1137±245 g and 29±2.4 weeks, respectively. During the study period, 78% of VLBW infants survived to discharge and 48% of survived infants had no major neonatal morbidity. VLBW infants who survived were evaluated in terms of major morbidities: bronchopulmonary dysplasia was detected in 23.7% of infants, necrotizing enterocolitis in 9.1%, blood culture proven late-onset sepsis (LOS) in 21.1%, blood culture negative LOS in 21.3%, severe intraventricular hemorrhage in 5.4% and severe retinopathy of prematurity in 11.1%. Hemodynamically significant patent ductus arteriosus was diagnosed in 24.8% of infants. Antenatal steroids were administered to 42.9% of mothers. CONCLUSION: The present investigation is the first multicenter study to include epidemiological information on VLBW infants in Turkey. Morbidity rate in VLBW infants is a serious concern and higher than those in developed countries. Implementation of oxygen therapy with appropriate monitoring, better antenatal and neonatal care and control of sepsis may reduce the prevalence of neonatal morbidities. Therefore, monitoring standards of neonatal care and implementing quality improvement projects across the country are essential for improving neonatal outcomes in Turkish NICUs.

Published
2019

4. Turkey (TR-ROP study): a prospective, multicentre study in 69 neonatal

Author

Bas, AY, Demirel, N, Koc, E, Isik, DU, Hirfanoglu, IM, Tunc, T, Sari, FN, Karatekin, G, Koklu, E, Altunhan, H, Turgut, H, Narter, F, Tarakci, N, Tekgunduz, KS, Ozkiraz, S, Aydemir, C, Ozdemir, A, Cetinkaya, B, Kazanci, E, Tastekin, A, Calkavur, S, Ozyurt, BM, Demirelli, Y, Asker, HS, Mutlu, B, Uygur, O, Ozkan, H, Armangil, D, Ozlu, F, Mert, MK, Ergin, H, Ozcan, B, Bas, EK, Okulu, E, Acunas, B, Celik, U, Uslu, SI, Mutlu, M, Demir, N, Eroglu, F, Gokmen, Z, Beken, S, Bayraktar, BT, Hakan, N, Kucuktasci, K, Orman, A, Comert, S, Ertugrul, S, Ustun, N, Sahin, O, Terek, D, Kale, Y, Konak, M, Yurttutan, S, Aydemir, O, Zenciroglu, A, Sarici, D, Guzoglu, N, Hamilcikan, S, Gursoy, T, Tuzun, F, Ors, R, Arslan, S, Akdag, A, Memisoglu, A, Yasa, B, Hekimoglu, B, Turan, O, Aylanc, H, Takci, S, Celik, T, Sahin, S, Kilic, I, Kara, C, Tunay, ZO, Celik, G, Gozen, I, Satirtav, G, Polat, N, Oral, AY, Tokgoz, M, Keles, S, Bilgin, B, Ugurbas, SC, Karaca, C, Keskek, NS, Ekinci, DY, Balci, O, Altan, EV, Bakbak, S, Ceylan, NA, Kimyon, S, Alyamac, G, Ture, G, Yildiz, M, Calis, F, Sizmaz, S, Sukgen, E, Cetin, EN, Ozcimen, M, Demir, ST, Atila, H, Ozal, A, Tufaner, G, Yucel, OE, Kola, M, Seven, E, Ozdek, S, Durukan, AH, Kal, A, Celebi, ARC, Koytak, IA, Alacamli, G, Esme, A, Catak, O, Perente, I, Sahin, A, Akcakaya, AA, Kiray, G, Nalcaci, S, Aksoy, U, Bakbak, B, Comez, A, Gursoy, H, Kabatas, EU, Petricli, IS, Yumusak, ME, Kirgiz, A, Uludag, G, Yaman, A, Dadaci, Z, Karatas, A, Celiker, H, Cebeci, Z, Esenulku, MC, Akkoyun, I, Ersan, I, Demir, S, Kadayifcilar, S, Unsal, AIA, and Hocaoglu, M

Abstract

Background To evaluate the prevalence, risk factors and treatment of retinopathy of prematurity (ROP) in Turkey and to establish screening criteria for this condition. Methods A prospective cohort study (TR-ROP) was performed between 1 April 2016 and 30 April 2017 in 69 neonatal intensive care units (NICUs). Infants with a birth weight (BW)=1500 g or gestational age (GA) 1500 g or GA> 32 weeks with an unstable clinical course were included in the study. Predictors for the development of ROP were determined by logistic regression analyses. Results The TR-ROP study included 6115 infants: 4964 (81%) with a GA 32 weeks. Overall, 27% had any stage of ROP and 6.7% had severe ROP. A lower BW, smaller GA, total days on oxygen, late-onset sepsis, frequency of red blood cell transfusions and relative weight gain were identified as independent risk factors for severe ROP in infants with a BW=1500 g. Of all infants, 414 needed treatment and 395 (95.4%) of the treated infants had a BW

Published
2018

5. Outcome of the Respiratory Syncytial Virus related acute lower respiratory tract infection among hospitalized newborns: a prospective multicenter study

Author

Kiray Bas, E., Koc, E., Hirfanoglu, I.M., Celik, U., Yalaz, M., Ergor, S.N., Duman, N., Iscan, B., Unal, S., Cakir, B., Ertugrul, S., Satar, M., Ozlu, F., Cevit, O., Bolat, F., Bilgili, G., Yigit, Y., Kurt, A., Tekgunduz, K.S., Caner, I., Yildiz, D., Kahvecioglu, D., Oygur, N., Erdogan, Y., Turkmen, M.K., Anik, A., Arsan, Saadet, Atasay, Begum, Ates, Can, Gokmen, Zeynel, Tunc, Turan, Akcakus, Mustafa, Zenciroglu, Aysegul, Akduman, Hasan, Cakir, Ufuk, ERDEVE, ÖMER, Alan, Serdar, Melekoglu, N.A., Celik, I., Korkmaz, A., Ozdemir, R., Karadag, A., Ozer, E., Ilhan, O., Mutlu, M., Aslan, Y., Erener- Ercan, T., Cetinkaya, M., Sahin, O., Akin, M.A., Okumus, N., Demirel, G., Kilic, A., Turkoglu-Unal, E., Bulbul, A., Takci, S., Anuk-Ince, D., Ciftdemir, N.A., Acunas, B., Ozkan, H., Koksal, N., Okulu, E., Demir, N., Tuncer, O., Dizdar, E.A., Oguz, S., Dilmen, U., Bozkaya, D., Sivasli, E., Alan, S., Neonatal Intensive Care Unit, Hitit University Corum Training and Research Hospital, Vedat Dolakay Cad. No: 90A/16 Gaziosmanpasa, Ankara, 06100, Turkey -- Erdeve, O., Division of Neonatology, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey -- Cakir, U., Division of Neonatology, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey -- Akduman, H., Division of Neonatology, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey -- Zenciroglu, A., Neonatal Intensive Care Unit, Dr Sami Ulus Maternity and Children Training and Research Hospital, Ankara, Turkey -- Akcakus, M., Division of Neonatology, Department of Pediatrics, Akdeniz University Medical School, Antalya, Turkey -- Tunc, T., Division of Neonatology, Department of Pediatrics, Gulhane Military School of Medicine, Ankara, Turkey -- Gokmen, Z., Neonatal Intensive Care Unit, Konya Training and Research Hospital, Konya, Turkey -- Ates, C., Department of Biostatistics, Ankara University School of Medicine, Ankara, Turkey -- Atasay, B., Division of Neonatology, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey -- Arsan, S., Division of Neonatology, Department of Pediatrics, Ankara University School of Medicine, Ankara, Turkey -- Anik, A., Adnan Menderes University, Faculty of Medicine, Aydin, Turkey -- Turkmen, M.K., Adnan Menderes University, Faculty of Medicine, Aydin, Turkey -- Erdogan, Y., Akdeniz University, Medical School, Antalya, Turkey -- Oygur, N., Akdeniz University, Medical School, Antalya, Turkey -- Kahvecioglu, D., Ankara University, School of Medicine, Ankara, Turkey -- Yildiz, D., Ankara University, School of Medicine, Ankara, Turkey -- Caner, I., Ataturk University, Faculty of Medicine, Erzurum, Turkey -- Tekgunduz, K.S., Ataturk University, Faculty of Medicine, Erzurum, Turkey -- Kurt, A., Balikesir Ataturk Government Hospital, Balikesir, Turkey -- Yigit, Y., Celal Bayar University, Faculty of Medicine, Manisa, Turkey -- Bilgili, G., Celal Bayar University, Faculty of Medicine, Manisa, Turkey -- Bolat, F., Cumhuriyet University, Faculty of Medicine, Sivas, Turkey -- Cevit, O., Cumhuriyet University, Faculty of Medicine, Sivas, Turkey -- Ozlu, F., Cukurova University, Faculty of Medicine, Adana, Turkey -- Satar, M., Cukurova University, Faculty of Medicine, Adana, Turkey -- Ertugrul, S., Dicle University, Faculty of Medicine, Diyarbakir, Turkey -- Cakir, B., Ankara Children's Health Hematology Oncology Research Hospital, Ankara, Turkey -- Unal, S., Ankara Children's Health Hematology Oncology Research Hospital, Ankara, Turkey -- Iscan, B., Dokuz Eylul University, School of Medicine, Izmir, Turkey -- Duman, N., Dokuz Eylul University, School of Medicine, Izmir, Turkey -- Ergor, S.N., Ege University, Faculty of Medicine, Izmir, Turkey -- Yalaz, M., Ege University, Faculty of Medicine, Izmir, Turkey -- Celik, I., Etlik Zübeyde Hanim Women's Health Teaching and Research Hospital, Ankara, Turkey -- Celik, U., Etlik Zübeyde Hanim Women's Health Teaching and Research Hospital, Ankara, Turkey -- Hirfanoglu, I.M., Gazi University, Faculty of Medicine, Ankara, Turkey -- Koc, E., Gazi University, Faculty of Medicine, Ankara, Turkey -- Sivasli, E., Gaziantep University, Faculty of Medicine, Gaziantep, Turkey -- Melekoglu, N.A., Gaziantep University, Faculty of Medicine, Gaziantep, Turkey -- Kiray Bas, E., Gaziantep Children's Hospital, Gaziantep, Turkey -- Bozkaya, D., Hacettepe University, Faculty of Medicine, Ankara, Turkey -- Korkmaz, A., Hacettepe University, Faculty of Medicine, Ankara, Turkey -- Ozdemir, R., Inönü University, Faculty of Medicine, Malatya, Turkey -- Karadag, A., Inönü University, Faculty of Medicine, Malatya, Turkey -- Ozer, E., Tepecik Training and Research Hospital, Izmir, Turkey -- Ilhan, O., Tepecik Training and Research Hospital, Izmir, Turkey -- Mutlu, M., Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey -- Aslan, Y., Karadeniz Technical University, Faculty of Medicine, Trabzon, Turkey -- Erener- Ercan, T., Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey -- Cetinkaya, M., Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkey -- Sahin, O., Kayseri Training and Research Hospital, Kayseri, Turkey -- Akin, M.A., Kayseri Training and Research Hospital, Kayseri, Turkey -- Okumus, N., Dr. Sami Ulus Maternity and Children Training and Research Hospital, Ankara, Turkey -- Demirel, G., Samsun Maternal and Child Health Hospital, Samsun, Turkey -- Kilic, A., Samsun Maternal and Child Health Hospital, Samsun, Turkey -- Turkoglu-Unal, E., Sisli Hamidiye Etfal Children Hospital, Istanbul, Turkey -- Bulbul, A., Sisli Hamidiye Etfal Children Hospital, Istanbul, Turkey -- Takci, S., Gaziosmanpasa University, Faculty of Medicine, Tokat, Turkey -- Anuk-Ince, D., Gaziosmanpasa University, Faculty of Medicine, Tokat, Turkey -- Ciftdemir, N.A., Trakya University, School of Medicine, Edirne, Turkey -- Acunas, B., Trakya University, School of Medicine, Edirne, Turkey -- Ozkan, H., Uludag University, Faculty of Medicine, Bursa, Turkey -- Koksal, N., Uludag University, Faculty of Medicine, Bursa, Turkey -- Okulu, E., Van Training and Research Hospital, Van, Turkey -- Demir, N., Yuzuncu Yil University, School of Medicine, Van, Turkey -- Tuncer, O., Yuzuncu Yil University, School of Medicine, Van, Turkey -- Dizdar, E.A., Zekai Tahir Burak Maternity Teaching Hospital, Ankara, Turkey -- Oguz, S., Zekai Tahir Burak Maternity Teaching Hospital, Ankara, Turkey -- Dilmen, U., Zekai Tahir Burak Maternity Teaching Hospital, Ankara, Turkey, Hitit Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Alan, S, Erdeve, O, Cakir, U, Akduman, H, Zenciroglu, A, Akcakus, M, Tunc, T, Gokmen, Z, Ates, C, Atasay, B, Arsan, S, Sakarya Üniversitesi/Tıp Fakültesi/Dahili Tıp Bilimleri Bölümü, Caner, İbrahim, and Çukurova Üniversitesi

Subjects
Male, Pediatrics, Neonatal intensive care unit, Turkey, viruses, health care facilities, manpower, and services, respiratory syncytial virus, Infant, Newborn, Diseases, Disease Outbreaks, 0302 clinical medicine, newborn, Medicine, 030212 general & internal medicine, Prospective Studies, Neonatal Intensive Care Unit, Respiratory system, Prospective cohort study, Respiratory Tract Infections, Cross Infection, Respiratory tract infections, Incidence (epidemiology), Obstetrics and Gynecology, Obstetrics & Gynecology, Prognosis, Respiratory Syncytial Viruses, Hospitalization, Treatment Outcome, Female, medicine.drug, Palivizumab, medicine.medical_specialty, education, Respiratory Syncytial Virus Infections, Antiviral Agents, 03 medical and health sciences, 030225 pediatrics, Intensive care, Intensive Care Units, Neonatal, Humans, outbreak, business.industry, Infant, Newborn, Outbreak, Infant, nosocomial, Newborn, Pediatrics, Perinatology and Child Health, Respiratory Syncytial Virus, Nosocomial, business
Abstract

Taylor and Francis Ltd, Aim: To determine the incidence and outcomes of respiratory syncytial virus (RSV)-related acute lower respiratory tract infection (ALRI) including morbidity, nosocomial infection and mortality among newborn infants who were admitted to the neonatal intensive care units (NICUs).Methods: A multicenter, prospective study was conducted in newborns who were hospitalized with community acquired or nosocomial RSV infection in 44 NICUs throughout Turkey. Newborns with ALRI were screened for RSV infection by Respi-Strip®-test. Main outcome measures were the incidence of RSV-associated admissions in the NICUs and morbidity, mortality and epidemics results related to these admissions.Findings: The incidence of RSV infection was 1.24% (n: 250) and RSV infection constituted 19.6% of all ALRI hospitalizations, 226 newborns (90.4%) had community-acquired whereas 24 (9.6%) patients had nosocomial RSV infection in the NICUs. Of the 250 newborns, 171 (68.4%) were full-term infants, 183 (73.2%) had a BW >2500 g. RSV-related mortality rate was 1.2%. Four NICUs reported seven outbreaks on different months, which could be eliminated by palivizumab prophylaxis in one NICU.Conclusion: RSV-associated ALRI both in preterm and term infants accounts an important percent of hospitalizations in the season, and may threat other high-risk patients in the NICU. © 2015 Taylor & Francis., Alan, S.; Neonatal Intensive Care Unit, Hitit University Corum Training and Research Hospital, Vedat Dolakay Cad. No: 90A/16 Gaziosmanpasa, Turkey; email: alanserdar@gmail.com

Published
2016

6. Pseudomonas aeruginosa infections due to electronic faucets in a neonatal intensive care unit

Author

Yapicioglu H., Gokmen T.G., Yildizdas D., Koksal F., Ozlu F., Kale-Cekinmez E., Mert K., and Çukurova Üniversitesi

Subjects
newborn, P. aeruginosa infection, electronic faucet
Abstract

PubMedID: 22085434 Aim: To evaluate the role of electronic faucets in a newborn intensive care unit during a Pseudomonas aeruginosa outbreak. Methods: After three patients had P. aeruginosa bacteremia, environmental cultures including those from patient rooms, incubator, ventilators, total parenteral nutrition solutions, disinfection solutions, electronic and hand-operated faucet filters/water samples after removing filters and staff hands were taken. Results: Only filters of electronic faucets and water samples after removing filters and one liquid hand soap showed P. aeruginosa (3-7 × 106 cfu/mL). We have removed the electronic faucets and new elbow-operated faucets were installed. Pulsed-field gel electrophoresis analysis of outbreak-blood culture isolates from two patients and isolates from electronic water faucets/one liquid hand soap indicated the presence of 90.7% genetically related subtype, probably from the same clone. Water cultures from new faucets were all clean after installation and after 7 months. Conclusion: We suggest that electronic faucets may be considered a potential risk for P. aeruginosa in hospitals, especially in high-risk units. © 2011 Paediatrics and Child Health Division (Royal Australasian College of Physicians).

Published
2012

7. A 6-year prospective surveillance of healthcare-associated infections in a neonatal intensive care unit from southern part of Turkey

Author

Yapicioglu H., Satar M., Ozcan K., Narli N., Ozlu F., Sertdemir Y., Tasova Y., and Çukurova Üniversitesi

Subjects
animal structures, surveillance, virus diseases, Healthcare-associated infections, neonatal intensive care unit, predominant microorganisms
Abstract

PubMedID: 20412409 Aim: To report the incidence of healthcare-associated infections (HAIs), site of infection and bacterial epidemiology in the Neonatal Intensive Care Unit in a university hospital in Adana, Turkey, between 2001 and 2006. Methods: During these years, HAIs were collected by an active surveillance system. Results: Five hundred one of 2832 infants hospitalised more than 72 h had 1124 HAI. The HAI incidence and incidence density ranged between 14.1 and 29.7 infections/100 patients, and 10.9-17.3 infections/1000 patient days within the study period; 61.5% of HAIs were ventilator-associated infections; 26.2% were bloodstream infections; 3.5% were urinary tract infections; 3.5% were necrotising enterocolitis (Stages II and III) and 1.4% was meningitis. The most frequent pathogens were gram-negative pathogens (75.6% of all infections) followed by gram-positive micro-organisms (21.4%) and Candida species (3.0%). Birthweight, gestational age and Apgar scores were lower and overall mortality rate (32.9% vs. 19.7%) and number of inpatient days were higher in patients with HAIs (for all P < 0.001) when compared with those who did not have HAIs. Furthermore, HAI rate was inversely related to birthweight (P < 0.001). Conclusion: In this study, the overall infection rate is high compared with developed countries and predominant micro-organisms are gram-negative enteric rods. These results strongly suggest the need for improving measures for prevention and control of HAIs in this hospital. © 2010 Paediatrics and Child Health Division (Royal Australasian College of Physicians).

Published
2010

Catalog

Books, media, physical & digital resources
See catalog results