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The p-values were incorrectly represented on pages 466 and 467. The level of statistical significance for ANOVA should be p < 0.05, not p < 0.5.Specific sentences are corrected as follows:Page 466• 'The results of fatty acid composition, biometry and hatching characteristics were compared between the different populations using ANOVA (p < 0.5).' should read 'The results of fatty acid composition, biometry and hatching characteristics were compared between the different populations using ANOVA (p < 0.05).'• 'The three populations examined exhibit differences in cyst diameters for both decapsulated and hydrated cysts (p < 0.5).' should read 'The three populations examined exhibit differences in cyst diameters for both decapsulated and hydrated cysts (p < 0.05).'• 'Except for El Melah and Timimoune, decapsulated cyst mean diameter presented no significant differences (p > 0.5).' should read 'Except for El Melah and Timimoune, decapsulated cyst mean diameter presented no significant differences (p > 0.05).'• 'The Bethioua population was significantly larger than the Timimoune and El Melah populations (p < 0.5).' should read 'The Bethioua population was significantly larger than the Timimoune and El Melah populations (p < 0.05).'• 'There were no significant differences between the mean size of the nauplii instar-1 from Timimoune and El Melah populations (p > 0.5).' should read 'There were no significant differences between the mean size of the nauplii instar-1 from Timimoune and El Melah populations (p > 0.05).'• 'The hatching efficiency for decapsulated and non-decapsulated cysts for the Timimoune population and that of both of the Bethioua and El Melah populations were found significantly different (p < 0.5).' should read 'The hatching efficiency for decapsulated and non-decapsulated cysts for the Timimoune population and that of both of the Bethioua and El Melah populations were found significantly different (p < 0.05).'• 'Table 1: Biometry and hatching characteristics of three Artemia populations from Algeria. Different superscripts in the same row denote significant differences (p < 0.5)' should read 'Table 1: Biometry and hatching characteristics of three Artemia populations from Algeria. Different superscripts in the same row denote significant differences (p < 0.05)' Page 467• 'Table 2: Fatty acids composition (percentage of the total fatty acids from the total lipids) and total identified fatty acids (mg g−1 dry weight) of the cysts from three Artemia populations of Algeria (means and standard deviation, n = 3). HUFA: highly unsaturated fatty acids; n-3 HUFA: ≥20:3n-3; n-6 HUFA: ≥20:2n-6. Different superscripts in the same row denote significant differences (p < 0.5)' should read 'Table 2: Fatty acids composition (percentage of the total fatty acids from the total lipids) and total identified fatty acids (mg g−1 dry weight) of the cysts from three Artemia populations of Algeria (means and standard deviation,n = 3). HUFA: highly unsaturated fatty acids; n-3 HUFA: ≥20:3n-3; n-6 HUFA: ≥20:2n-6. Different superscripts in the same row denote significant differences (p < 0.05)' • 'Bethioua and El Melah population showed significant differences (p < 0.5) in the percentage of 10 fatty acids (14:1; 16:0; 16:1n-7; 17:0; 18:0; 18:3n-3; 18:4n-3; 20:3n-3; 20:4n-3 and 20:5n-3).' should read 'Bethioua and El Melah population showed significant differences (p < 0.05) in the percentage of 10 fatty acids (14:1; 16:0; 16:1n-7; 17:0; 18:0; 18:3n-3; 18:4n-3; 20:3n-3; 20:4n-3 and 20:5n-3).' • 'There were significant differences between Timimoune and El Melah population (p < 0.5) in the percentage of four fatty acids (15:0, 18:0, 18:1n-7 and 18:2n-6).' should read 'There were significant differences between Timimoune and El Melah population (p < 0.05) in the percentage of four fatty acids (15:0, 18:0, 18:1n-7 and 18:2n-6).' • 'There were no significant differences (p > 0.5) between the Bethioua and Timimoune population in fatty acid composition.' should read 'There were no Significant differences (p > 0.05) between the Bethioua and Timimoune population in fatty acid composition.'

A large fraction of atmospheric organic aerosol (OA) originates from natural emissions that are oxidized in the atmosphere to form secondary organic aerosol (SOA). Isoprene (IP) and monoterpenes (MT) are the most important precursors of SOA originating from forests. The climate impacts from OA are currently estimated through parameterizations of water uptake that drastically simplify the complexity of OA. We combine laboratory experiments, thermodynamic modeling, field observations, and climate modeling to (1) explain the molecular mechanisms behind RH-dependent SOA water-uptake with solubility and phase separation; (2) show that laboratory data on IP- and MT-SOA hygroscopicity are representative of ambient data with corresponding OA source profiles; and (3) demonstrate the sensitivity of the modeled aerosol climate effect to assumed OA water affinity. We conclude that the commonly used single-parameter hygroscopicity framework can introduce significant error when quantifying the climate effects of organic aerosol. The results highlight the need for better constraints on the overall global OA mass loadings and its molecular composition, including currently underexplored anthropogenic and marine OA sources., published version, peerReviewed

Introduction: Lung transplantation (LT) has been considered an alternative therapeutic approach in terminal patients. However, this process in COPD is not controversy-free. This paper aimed to analyze 30-day mortality (PM) patterns and their risk factors in COPD patients undergoing LT. Patients and method: A retrospective cohort with 107 COPD patients, transplanted at the University La Fe Valencia, Spain, treated from January 1991 to December 2008. Demographics values, degree of dyspnoea, diagnosis, BODE index, single versus bilateral LT, cardio-pulmonary bypass, donor age, steroid dependence, presence of bronchiectasis, retrograde perfusion, transfusion of blood products, and PaO2/FiO(2) were analyzed. Continuous variables were expressed as mean +/- SD and categorical variables as absolute frequency and percentage. A Cox regression model was used for multivariate analysis. Results: Ninety-four men and 13 women of a mean age of 52.58 +/- 8.05 years were transplanted. Of all patients, 75% obtained a BODE score above 7. There were 76 bilateral LT. PM was established at 14%. Main causes of death were infection (53.3%) and surgical complications (33.3%). Presence of bronchiectasis and chronic use of corticosteroids, donor/recipient difference.in size and presence of fat in retrograde perfusion fluid were important risk factors for PM. Moreover, PaO2/FiO(2) ratio at 6h was a protective factor for the event, thus a higher ratio value, lowered the risk of PM. Conclusions: LT is a procedure with a high PM rate. Use of corticosteroids, the presence of bronchiectasis and fat emboli in the retrograde reperfusion, and PaO2/FiO(2) significantly determine PM. (C) 2016 Elsevier Espana, S.L.U. All rights reserved.

Introduction: Lung transplantation (LT) is a therapeutic option with controversial results in chronic obstructive pulmonary disease (COPD). We aimed to analyze the outcomes of transplantation in terms of lung function and to identify prognostic factors. Method: A retrospective analysis of 107 patients with COPD receiving lung transplants in the La Fe Hospital between 1991 and 2008 was performed. Preoperative variables, pulmonary function tests before and after LT, surgical procedure variables and long-term monitoring, expressed as mean or percentage, as applicable, were analyzed. Spirometric results before and after LT were analyzed. Linear or logistic regression were used for multivariate analysis depending on the variable. Results: Ninety-four men (87.9%) and 13 women (12.1%) were transplanted, with a mean age +/- standard deviation of 52.58 +/- 8.05 years; 71% of LTs were double-lung transplantations. Spirometric values improved after LT: FVC: +1.22 L (+34.9%), FEV1 : +1.66 L (+56.7%) and FEF25-75: +1.85 L (+50.8%); P = .001. This functional improvement was maintained after 5 years only in the group with BODE score > 7 (P = .001). Recipient height, type of LT, use of extracorporeal circulation during the surgical procedure, presence of bronchiolitis obliterans syndrome and the age and cause of death of the donor significantly influenced lung function over time. Conclusions: LT improves lung function in COPD patients. This improvement was maintained at 5 years only in patients with BODE > 7. Double lung transplantation provides better functional results than singlelung transplantation. (C) 2014 SEPAR. Published by Elsevier Espana, S.L.U. All rights reserved.

Background and Purpose— To determine the effect of B vitamin treatment on the incidence of cancer among patients with stroke or transient ischemic attack. Methods— A total of 8164 patients with recent stroke or transient ischemic attack were randomly allocated to double-blind treatment with 1 tablet daily of placebo or B vitamins (2 mg folic acid, 25 mg vitamin B 6 , 500 μg vitamin B 12 ) and followed for a median of 3.4 years for any cancer as an adverse event. Results— There was no significant difference in the incidence of any cancer among participants assigned B vitamins compared with placebo (4.04% versus 4.59%; risk ratio, 0.86; 95% CI, 0.70–1.07) and no difference in cancer mortality (2.35% versus 2.09%; risk ratio, 1.09; 0.81–1.46). Among 1899 patients with diabetes, the incidence of cancer was higher among participants assigned B vitamins compared with placebo (5.35% versus 3.28%; adjusted risk ratio, 2.21; 1.31–3.73), whereas among 6168 patients without diabetes, the incidence of cancer was lower among participants assigned B vitamins compared with placebo (3.66% versus 5.03%; adjusted risk ratio, 0.67; 0.51–0.87; P for interaction=0.0001). Conclusions— Daily administration of folic acid, vitamin B 6 , and vitamin B 12 to 8164 patients with recent stroke or transient ischemic attack for a median of 3.4 years had no significant effect, compared with placebo, on cancer incidence or mortality. However, a post hoc subgroup analysis raises the hypothesis that folic acid treatment may increase the incidence of cancer among diabetics and reduce the incidence of cancer among nondiabetics with a history of stroke or transient ischemic attack. Clinical Trial Registration— URL: www.clinicaltrials.gov . Unique identifier: NCT00097669. URL: www.controlled-trials.com . Unique identifier: ISRCTN74743444.