1. 'Perinatal outcomes after in vitro fertilization – a comparison of the national live birth registry with a tertiary cohort and an IVF cohort.'
- Author
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Mitter, V R, Fasel, Pascale Denise, Berlin, C, Amylidi-Mohr, S, Mosimann, B, Zwahlen, M, von Wolff, M, and Kohl Schwartz, A
- Subjects
610 Medicine & health ,reproductive and urinary physiology ,360 Social problems & social services - Abstract
Introduction:���In vitro fertilization (IVF) treatment is performed increasingly in Switzerland. Conception by IVF negatively affects obstetric and perinatal outcomes. Possible risk factors are parental health and subfertility, gonadotropin stimulation, gamete manipulation or culture of the embryo. Our primary aim was to assess the impact of IVF on perinatal outcomes in comparison to i) children born in tertiary care (university hospital), ii) all children born in Switzerland in the same time; and secondary, to address the effect of gonadotropin stimulation. Methods:���We performed IVF using 75IU-300IU gonadotropin per day to stimulate ovarian growth, or in the unstimulated natural cycle, where we collected the single oocyte. Fresh cleavage embryos were transferred on day 2 or 3. We recruited tertiary care births during first trimester check-up. We assessed differences in continuous perinatal outcomes, birthweight and gestational age, using linear regression; and the relative risk (RR) for preterm delivery (
- Published
- 2021