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1. Colitis eosinofílica subserosa: reporte de caso en un hospital privado de Lima - Perú

Author

Walter Zagaceta Torres, Miguel Fernán Valverde Huamán, and Jamik Jaker Mathios Castro

Subjects
Gastroenterology
Abstract

La colitis eosinofílica es una patología gastrointestinal infrecuente que pertenece al grupo de las denominadas “enfermedades primarias eosinofílicas del tracto digestivo”. Existen 3 tipos: mucosa, transmural (muscular) y subserosa. Presentamos el caso de un paciente varón, de 23 años de edad, con cuadro clínico de dolor abdominal, náuseas, diarrea crónica y presentación de ascitis. Se descarta etiologías parasitarias y otras secundarias. La endoscopia digestiva alta no fue contributoria. Mediante colonoscopia se observa características de inflamación en el ileon distal y colon ascendente, cuyos hallazgos histológicos son compatibles con colitis eosinofílica. El estudio de líquido ascítico es sugestivo de ascitis eosinofílica. El paciente recibió tratamiento de inducción con prednisona a 40mg diarios por vía oral, lográndose remisión a las 2 semanas, continuando con terapia de mantenimiento a base de prednisona con retiro progresivo de la dosis. Se logra control de la enfermedad de manera exitosa.

Published
2023

4. Influence of the surface modification of BaTiO3 nanoparticles by hydrolyzed chitosan obtained from shrimp exoskeletons on the optical response intensity of the second harmonic

Author

Luis M. Angelats-Silva, Fredy Pérez-Azahuanche, José A. Roldan-Lopez, Nikita A. Emelianov, Rudy B. Céspedes-Vásquez, and Miguel A. Valverde-Alva

Subjects
Mechanics of Materials, Mechanical Engineering, General Materials Science, Condensed Matter Physics
Abstract

Ferroelectric nanoparticles, due to their high non-linear optical response, are of considerable practical interest for their use as nanoprobes for the study of biological materials by multiphoton microscopy methods. To prevent toxic effects, it is necessary to modify the surface using biocompatible polymers. Here we report the results of the study on the effect of surface modification of BaTiO3 nanoparticles with hydrolyzed chitosan obtained from shrimp exoskeletons (Penaeus vannamei). It was found that increasing of the hydrolyzed chitosan concentration in the solution during surface modification from 1 to 3% leads to a significant reduction in nanoparticle agglomeration, while the intensity of the second harmonic generation changes insignificantly. Graphical abstract

Published
2022

5. Reparación de la hernia paraestomal. Estudio observacional prospectivo basado en el Registro Español de Hernia Incisional (EVEREG)

Author

Manuel López-Cano, José Antonio Pereira, Victor Rodrigues-Gonçalves, Mireia Verdaguer-Tremolosa, Pilar Hernández-Granados, Alejandro Bravo-Salvá, Antonio Utrera González, José M. Capitán Vallvey, Matías Pradas, Daniel Pérez Gomar, Manuel Bustos, Francisco Antonio Herrera Fernández, Juan A. Blanco, Joaquim Robres Puig, Rafael Villalobos, Dolors Güell Puigcercós, José María Puigcercós Fusté, Vicente Ayuso Osuna, Marta Piñol, Carles Olona Cases, Francisco Martínez Ródenas, Jordi Comajuncosas, Enric Sebastián Valverde, Sara Amador, Jaume Gelonch, Helena Vallverdú, Magda Abelló Sala, Antonio Veres Gómez, Rosa Gamón, Pedro García Peche, Miguel González Valverde, Miguel Angel Martín Blanco, Ramón J. Ferri, Elena Martí Ciñat, Providencia García Pastor, Carlos Montero, Miguel Ángel Lorenzo Liñán, Vicente Barbero, Miguel Ángel Morlan, José María Jover, Isabel Delgado Lillo, María Mercedes Sanz Sánchez, Leire Zarain Obrador, Alejandro Lusilla, Juan Jesús Cabeza Gómez, Teresa Butrón, Guillermo Supelano Eslait, José Luis Álvarez Conde, Baltasar Pérez Saborido, Mario Rodríguez López, Santiago Revuelta Álvarez, Pedro Trillo Parejo, José Luis Rodicio, Antonio Blanco, Jacobo Trébol López, Ramón Castañera González, Gian Pier Protti, Damián Turiño Luque, Juan José Espert, Carmen Zaragoza, Marta Hidalgo Pujol, Daniel Carmona Navarro, Álvaro Valdés de Anca, Laura Fresno de Prado, Antonio Nieto Soler, Francisca Vasco Rodríguez, Roberto Lozoya Trujillo, M Pilar Anaya Reig, M Mercedes Sanz Sánchez, José Bueno Lledó, Salvador Pous Serrano, Elena Martí Cuñat, Ernest Bombuy Giménez, Esther Mans, Aparicio García, Elena Ortega Ortega, Enric Sebastián, Carlos Hoyuela Alonso, Raquel Grajal Marino, Lofti Elmalaki Hossain, Raul Medina, José Daniel Sánchez, Tomas Ratia Giménez, Antonio López, Rosa Ana García Díaz, and Itziar Larrañaga

Subjects
03 medical and health sciences, 0302 clinical medicine, business.industry, Medicine, Surgery, 030230 surgery, business, Humanities
Abstract

Resumen Introduccion Los resultados de la reparacion de la hernia paraestomal (HP) basados en datos provenientes de registros son escasos. El objetivo del presente trabajo es analizar los datos recogidos sobre la HP en el Registro Nacional de Hernia Incisional (EVEREG) y asi evaluar las practicas actuales y resultados en la reparacion de una HP. Metodos Se analizan los datos de la cohorte de HP registradas en el periodo desde julio de 2012 hasta junio de 2018. Se analizan las complicaciones, recidivas y factores asociados a ellas de la cohorte completa de HP, independientemente del tipo de estoma al que se asocian. Posteriormente, se realiza el mismo analisis del grupo de HP con relacion a una colostomia (grupo mas numeroso). Resultados Se estudiaron 353 HP. De estas, 259 (73%) fueron HP en el contexto de una colostomia terminal, 74 (21%) en el de una ileostomia terminal y 20 (6%) en el de una ureteroileostomia (Bricker). La edad media global fue de 68,7 ± 11,1 anos y 135 (38%) pacientes fueron del sexo femenino. El abordaje abierto y la cirugia electiva fueron predominantes (78% y 92%, respectivamente). El 99% se reparo con una malla sintetica no absorbible. Las complicaciones postoperatorias globales fueron altas (30,6%), asi como la recurrencia global (27,5%) tras un seguimiento medio de 9,4 meses. Conclusiones La reparacion de la HP es poco frecuente comparada con el conjunto de reparaciones de la hernia incisional. La cirugia de la HP parece relacionarse con un porcentaje elevado de complicaciones postoperatorias y recidiva.

Published
2021

6. Uso de modelos en vídeo para el entrenamiento en habilidades terapéuticas en estudiantes de Psicología y otras disciplinas sanitarias

Author

Monica Hernandez Lopez, Jose Antonio Muela Martinez, Beatriz Montes Berges, Maria Aranda Lopez, and Miguel Rodriguez Valverde

Subjects
Therapeutic skills, Competencias prácticas, Health, Practical competencies, Habilidades terapéuticas, Psychology, Video, Modelado, Salud, Modelling, Psicología
Abstract

[EN] This paper presents an innovative teaching experience carried out as part of a project in the Teaching Innovation Program at the University of Jaén (PIMED-UJA 2019-2023). The main goal of this project was the production of a series of brief training videos that modelled specific skills in assessment and intervention, in order to facilitate the acquisition of procedural skills specific to the degrees in Psychology and Nursing, as well as to the Health Psychology Masters degree. Faculty from different courses of these degrees (all of them registered healthcare psychologists with experience in their respective domains) scripted different therapy interactions that depicted specific therapeutic skills. The different roles (therapist and client) were played by professional actors that prepared the scripts and received specific feedback from the involved faculty, both before and during the recording sessions. The paper presents results regarding the use of these training videos in three different courses: Foundations of Psychological Assessment, Psychosocial Sciences in Healthcare, and Third Wave Behavioral Therapies in Healthcare Contexts. Students exposed to the training videos showed reductions in anticipatory anxiety, as well as increases in selfefficacy and the perceived utility of training for their future development as healthcare professionals., [ES] En este trabajo se presenta una experiencia de innovación docente realizada dentro del Plan de Innovación y Mejora Docente de la Universidad de Jaén (PIMED-UJA 2019-2023). El objetivo fundamental fue generar una serie de vídeos que modelaran habilidades de evaluación e intervención, a fin de facilitar la adquisición de competencias procedimentales específicas de los grados en Psicología, Enfermería y del máster en Psicología General Sanitaria. Para la elaboración de los vídeos, el profesorado de diferentes asignaturas, psicológos sanitarios con amplia experiencia, guionizaron situaciones de terapia donde se mostraban habilidades concretas. Los participantes de los vídeos fueron actores profesionales que recibieron los guiones así como feedback tanto antes como durante la grabación. En este trabajo se presentan los resultados de la utilización de estos vídeos en tres asignaturas: Fundamentos de Evaluación Psicológica, Ciencias Psicosociales Aplicadas a los Cuidados de la Salud y Terapias de Tercera Generación en el Ámbito de la Salud. El alumnado al que se presentó los vídeos mostró una reducción de la ansiedad para enfrentarse a situaciones de interacción terapéutica, y un incremento de la autoeficacia y de la utilidad percibida de las herramientas utilizadas en su formación como futuros profesionales de la salud.

Published
2022

7. CO distributions retrieved from TGO NOMAD SO using multiple orders

Author

Nao Yoshida, Shohei Aoki, Ann Carine Vandaele, Hiromu Nakagawa, Ian Thomas, Justin Erwin, Frank Daerden, Loïc Trompet, Isao Murata, Naoki Terada, Lori Neary, Miguel Lopez-Valverde, Ashimananda Modak, Geronimo Villanueva, Giuliano Liuzzi, Yasumasa Kasaba, Manish Patel, Bojan Ristic, Giancarlo Bellucci, and Jusé Juan López-Moreno

Abstract

An upward transport of water via the Hadley cell has been suggested as one of the mechanisms to transport water vapor to the upper atmosphere [Shaposhnikov et al., 2019], which would enhance the hydrogen escape on Mars [cf. Chaffin et al., 2017]. Carbon monoxide is one of the tracers which can measure the dynamics in the Martian atmosphere because CO distribution is a combination of photochemistry and dynamics. Above ~60 km altitude, the CO mixing ratio increases with altitude due to the production from photodissociation of CO2 and is further enhanced around the polar regions because of downwelling from the thermosphere [Daerden et al., 2019; Holmes et al., 2019; Olsen et al., 2021; Yoshida et al., accepted]. In the lower atmosphere, CO is recycled to CO2 by the catalytic cycle by odd hydrogen. The photochemical lifetime of CO is too slow, and then its lifetime is ~6 years in the lower atmosphere [Krasnopolsky, 2007]. Thus, seasonal variation of CO in the lower atmosphere is a consequence of CO2 sublimation/condensation at the polar cap [Encrenaz et al., 2006; Smith et al., 2009, 2021]. In addition, transport of rich CO atmosphere from southern to northern hemispheres during Ls = 90 – 180 has been measured by Smith et al. (2008, 2018) as predicted due to the breaking of the polar vortex by the GCM model. Although the vertical distribution of CO VMR is an index to determine the condensation of CO2, photochemistry, and dynamics, there is no direct comparison between measurements and simulations because we did not obtain the CO vertical distribution before the Trace Gas Orbiter (TGO) ExoMars mission. To clarify the vertical and horizontal transport of CO in the Martian atmosphere, we investigate the CO VMR retrieved from the solar occultation (SO) channel of Nadir and Occultation for MArs Discovery (NOMAD) instrument aboard TGO [Vandaele et al., 2018].The SO channel operates at wavenumbers from 2325.6 to 4347.8 cm-1 with relatively high spectral resolution (R = 17,000). CO (2-0) band spectra features between 3970.7 and 4360.1 cm-1 are measured regularly in orders 186 to 191 of the instrument. We retrieved CO number densities using CO spectra features in orders 186 to 191 and radiative transfer code, ASIMUT [Vandaete et al., 2006], based on the Optimal Estimation Method [Rogers, 2006]. ASIMUT was performed for each spectrum at each tangential altitude independently [e.g., Aoki et al., 2019]. The latest updated instrument calibrations [Villanueva et al., submitted; Thomas et al., 2022] have been applied. We used the GEM-Mars model temperature and CO2 profiles [Neary et al., 2018; Daerden et al., 2019] to derive the CO VMR. The CO spectra were investigated from April 2018 to September 2021, corresponding from MY 34 Ls ~ 150 to MY 36 Ls ~ 105. The total number of dataset is 31,000.Firstly, we found that the retrieved CO VMR in orders 187 to 191 does not correspond to that in order 186 below ~60 km altitude. The CO VMR derived from orders 187 to 191 is underestimated. The strongest 2-0 band of CO is located at 4288.3cm-1, which corresponds to order 190, and it saturates around ~60 km. The saturation of CO lines would be related to the underestimation of CO VMR. When we tested the retrieval sensitivity of saturated lines in order 186, the underestimation of CO VMR also appears below 40 km altitude in the case that we perform the ASIMUT using the entire wavenumber range of order 186 (4179.0 – 4212.2 cm-1) compared with using a partial wavenumber range, 4189.0 – 4198.0 cm-1, of order 186. To avoid the underestimation of CO VMR, the retrieved CO VMR derived from CO spectra in the orders 187 – 191 is limited between 60 and ~110 km altitude, that from CO spectra in order 186 is limited between 40 and ~110 km, and that from CO spectra in 4189.0 – 4198.0 cm-1 is limited between the near-surface to 40 km altitude.The retrieved CO VMR distributes from 300 to ~5000 ppm. In the polar regions, the CO VMR increases above ~40 km and reaches 4000 ppm at 70 km, which is attributed to the production of CO from photodissociation of CO2 and transport of CO-enriched air via meridional circulation [Daerden et al., 2019]. That is consistent with the results measured by the Atmospheric Chemistry Suite aboard TGO [Olsen et al., 2021]. In the lower atmosphere, the enriched CO VMR up to ~3500 ppm appears from 90 to 200 in Ls in the southern hemisphere, which would be attributed to the CO2 condense in the southern winter season. We will report the CO distribution in more detail while distinguishing the dataset into season and latitude along with altitude.

Published
2022

8. Simulation of the atomic deuterium density and escape at Mars and comparison with MAVEN/IUVS observations

Author

Jean-Yves Chaufray, Francisco Gonzalez-Galindo, Margaux Vals, Loic Rossi, Franck Montmessin, Franck Lefevre, François Leblanc, Ronan Modolo, François Forget, Ehouarn Millour, Gabriella Gilli, Miguel Lopez-Valverde, Majd Mayyasi, and Cardon, Catherine

Subjects
[SDU] Sciences of the Universe [physics]
Abstract

The D/H ratio is a key parameter to understand the atmospheric evolution of a planet. On Mars a D/H ~ 5 times larger than the ratio on Earth is measured. This large ratio can be explained by a preferential escape of the hydrogen compared to the deuterium due to its lower mass. However, while the thermal escape (Jeans escape) is strongly mass dependent other non-thermal processes are less mass dependent and would impact the time needed to fractionate the water from the terrestrial value to the current value. After the first detections of the deuterium Lyman-α emission from Earth (Bertaux et al. 1992, Krasnopolsky et al. 1998), the mission MAVEN performed the first systematic observations of the atomic deuterium Lyman-α emission around Mars showing a brightness of several hundreds of Rayleigh near Mars winter solstice (Clarke et al. 2017, Mayyasi et al. 2017), much larger than the Earth detections done near aphelion (~ 20 – 50 Rayleighs). This seasonal variation of the deuterium Lyman-α brightness is consistent with the variations of the hydrogen Lyman-α brightness observed from Mars Express (Chaffin et al. 2014, Chaufray et al. 2021), HST (Clarke et al. 2014), and MAVEN/IUVS (Clarke et al. 2017, Chaffin et al. 2018) and should result from the processes transporting the water vapor from the lower atmosphere to the upper atmosphere (Vals et al. 2022). In this work we will present preliminary simulations of the 3D deuterium abundance in the Martian upper atmosphere (Fig. 1) using a 3D time dependent global circulation model, including the chemical reactions between HD and HDO with the ions in the upper atmosphere, its extension in the exosphere, and a comparison of the simulated D Lyman-α brightness with the brightness measured by MAVEN/IUVS (Mayyasi et al. 2017) for the Martian year 33. Fig. 1 Simulated average dayside and nightside D density at different altitudes in the thermosphere and exosphere along one Martian year. We will also present first results of the simulated non-thermal escape of H and D produced by collisions between hot oxygen with H, D, H2 and HD as well as the escape of planetary H+ and D+ driven by the solar wind interaction. We will compare the D and H thermal escape rate with the non-thermal escape rates. References: Bertaux et al. (1992), in ESOC conference and workshop proceedings, 44, 459. Chaffin, M. et al. (2014), Geophys. Res. Lett., 41, 314-320 Chaffin, M. et al. (2018), J. Geophys. Res., 123, 2192-2210 Chaufray et al., (2021), Icarus, 353,113498 Clarke et al. (2014), Geophys. Res. Lett., 41, 8013-8020 Clarke et al. (2017), J. Geophys. Res., 122, 2336-2344 Krasnopolsky et al., (1998), Science, 280, 1576 Mayyasi et al., (2017), J. Geophys. Res., 122, 10811-10823 Vals et al. (2022), J. Geophys. Res., under revisions

Published
2022

9. Measurements of water and its D/H as released from both Martian polar caps

Author

Geronimo Villanueva, Giuliano Liuzzi, Shohei Aoki, Shane Stone, Adrian Brines, Ian Thomas, Miguel Lopez-Valverde, Loic Trompet, Justin Erwin, Frank Daerden, Bojan Ristic, Michael Smith, Michael Mumma, Sara Faggi, Vincent Kofman, Severine Robert, Lori Neary, Manish Patel, Giancarlo Bellucci, and Ann-Carine Vandaele

Abstract

Introduction The large enrichments of D/H currently measured in atmospheric water suggest that a large fraction, beyond 80%, of this water was lost over time1,2, and Ar and O isotopic ratios measured with MAVEN3 and TGO4 indicate Mars has lost a large fraction of its atmosphere. As we attempt to trace back the history of water on Mars, it is unknown how much water remains locked in non-labile/sub-surface reservoirs, and an important question is whether all current labile reservoirs have evolved in the same way and undergone extensive exchange. New measurements with TGOWe have analyzed data over the entirety a Martian year as measured with TGO/NOMAD, which probed the release of water from the two polar caps using the instrument’s solar occultation mode. Specifically, the measurements presented here have been collected by the NOMAD10 instrument suite onboard TGO. The data were collected employing the Solar Occultation (SO) channel/mode of the instrument. Interpretation and extraction of molecular abundances from the calibrated data is done by employing the Planetary Spectrum Generator (PSG, https://psg.gsfc.nasa.gov)11, and as reported in 12. The model employs a layer-by-layer line-by-line method in a spherical and refractive geometry. We employ the latest linelists for H2O, HDO, and CO2 as compiled in the HITRAN-2020 database13, which are complemented to include the latest H2O and HDO broadening coefficients for a CO2 atmosphere14,15. Probing the seasonal release from both capsDuring Martian Year 34, the planet was engulfed in a global dust storm (GDS) that greatly perturbed the temperature and vertical structure of the Martian atmosphere. In addition, the lingering effects of the GDS were joined by a large regional dust storm that started during late southern summer (LS 320). These two major events greatly affected the climate of Mars, primarily leading to a strong increase in atmospheric temperature, a substantial rise in altitude of the hygropause, and subsequent transport of water to unexpectedly high altitudes16–22. Interestingly, during the GDS when the northern hemisphere was in the winter season, the climate was substantially warmer there than normal23–25, leading to high-altitude water also in the northern hemisphere. Typically, the largest seasonal water columns are observed during summer in the northern hemisphere26, and that may be true in MY35, but the vertical profile of water is highly compact (confined to altitudes below 20 km), even at the peak of northern summer (LS 90-130). In all cases (all seasons and regions of the planet) the D/H declines quickly above the hygropause, from a nominal value above 5 VSMOW to a very low value near Discussions and conclusionsThe new results presented here, which probe the vertical profiles of water and D/H for both seasonal caps, together with previous ground-based and orbital measurements, suggest a common and highly enriched value for this labile reservoir of water. Atmospheric D/H behaves as an integrator of the differential individual atomic (H and D) escape rates, and therefore without any new supply of water into the system, the D/H of the labile sources will continue to increase. Among other phenomena, the chaotic changes in obliquity that Mars has experienced, and the corresponding impact on climate and regions of ice stability28,29, could lead to large exchanges between the reservoirs and further homogenization of the D/H across the planet. Thus, the D/H value of the polar caps could be similar to the modern labile D/H value observed in the seasonal releases. References1. Jakosky, B. M. Annual Review of Earth and Planetary Sciences 49, 71–93 (2021).2. Villanueva, G. L. et al.. Science 348, 218–221 (2015).3. Jakosky, B. M. et al. Science (2017) doi:10.1126/science.aai7721.4. Alday, J. et al. JGR: Planets 126, e2021JE006992 (2021).5. Scheller, E. L., et al. Science 372, 56–62 (2021).6. Plaut, J. J. et al. Science 316, 92 (2007).7. Zuber, M. T. et al. Science 282, 2053 (1998).8. Byrne, S. & Murray, B. C. JGR: Planets 107, 11-1-11–12 (2002).9. Fishbaugh, K. E. & Head, J. W. Icarus 174, 444–474 (2005).10. Vandaele, A. C. et al. Planetary and Space Science 119, 233–249 (2015).11. Villanueva, G. L., et al. JQSRT 217, 86–104 (2018).12. Villanueva, G. L. et al. Science Advances (2021) doi:10.1126/sciadv.abc8843.13. Gordon, I. E. et al. JQSRT 107949 (2022) doi:10.1016/j.jqsrt.2021.107949.14. Devi, V. M. et al. JQSRT 187, 472–488 (2017).15. Régalia, L. et al.JQSRT 231, 126–135 (2019).16. Aoki, S. et al. JGR: Planets 124, 3482–3497 (2019).17. Belyaev, D. A. et al. GRL 48, e2021GL093411 (2021).18. Chaffin, M. S. et al. Nat Astron 5, 1036–1042 (2021).19. Heavens, N. G. et al. Nature Astronomy 2, 126–132 (2018).20. Holmes, J. A. et al. Earth and Planetary Science Letters 571, 117109 (2021).21. Neary, L. et al. GRL 47, e2019GL084354 (2020).22. Stone, S. W. et al. Science (2020) doi:10.1126/science.aba5229.23. Daerden, F. et al. JGR: Planets n/a, e2021JE007079 (2022).24. Montabone, L. et al. JGR: Planets 125, e2019JE006111 (2020).25. Rossi, L. et al. GRL 48, e2020GL090962 (2021).26. Crismani, M. M. J. et al. JGR: Planets 126, e2021JE006878 (2021).27. Laskar, J. et al. Icarus 170, 343 (2004).28. Jakosky, B. M., Henderson, B. G. & Mellon, M. T. JGR: Planets 100, 1579–1584 (1995).29. Levrard, B., Forget, F., Montmessin, F. & Laskar, J. JGR: Planets 112, (2007).

Published
2022

10. Two Martian years at Mars: Observations by NOMAD on ExoMars Trace Gas Orbiter

Author

Ann Carine Vandaele, Frank Daerden, Ian R. Thomas, Cédric Depiesse, Justin Erwin, Zachary Flimon, Lori Neary, Arianna Piccialli, Bojan Ristic, Loïc Trompet, Sébastien Viscardy, Yannick Willame, Shohei Aoki, Jean-Claude Gérard, Geronimo Villanueva, Jon Mason, Manish Patel, Giancarlo Bellucci, Miguel Lopez-Valverde, and Jose Juan Lopez-Moreno

Abstract

The NOMAD (“Nadir and Occultation for MArs Discovery”) spectrometer suite on board the ExoMars Trace Gas Orbiter (TGO) has been designed to investigate the composition of Mars' atmosphere, with a particular focus on trace gases, clouds, and dust. The instrument probes the ultraviolet and infrared regions covering large parts of the 0.2-4.3 µm spectral range [1,2], with 3 spectral channels: a solar occultation channel (SO – Solar Occultation; 2.3–4.3 μm), a second infrared channel capable of nadir, solar occultation, and limb sounding (LNO – Limb Nadir and solar Occultation; 2.3–3.8 μm), and an ultraviolet/visible channel (UVIS – Ultraviolet and Visible Spectrometer, 200–650 nm). NOMAD performs solar occultation, nadir and limb observations dedicated to the determination of the composition and the structure of the Martian atmosphere. TGO started its science phase in April 2018 and instruments have now been accumulating data for more than two Martian years. We will present selected results obtained by the NOMAD instrument covering the atmosphere composition with observations of several trace gases, dust, and clouds. We also report on the different discoveries highlighted by the instrument by pointing to a series of contributions to this conference that will present in detail several specific studies, like recent progress in the instrument calibration, the latest CO2 and temperature vertical profiles, studies of aerosol nature and distribution, water vapor profiles and variability, carbon monoxide vertical distribution, ozone vertical profiles, climatology and relation with water, airglow observations, detection of CO2 ice clouds, surface ices and in general advances in the analysis of the spectra recorded by the three channels of NOMAD. References [1] Vandaele, A.C., et al., 2015. Planet. Space Sci. 119, 233-249. [2] Vandaele et al., 2018. Space Sci. Rev., 214:80, doi.org/10.1007/s11214-11018-10517-11212.

Published
2022

11. Effect of the magnetic field on the synthesis of colloidal silver and gold nanoparticles by laser ablation in bidestilated water

Author

Juan A. Vega-González, Juan C. Rodríguez Soto, Luis Angelats-Silva, Jhenry F. Agreda-Delgado, Claver W. Aldama-Reyna, Miguel A. Valverde-Alva, and Julio C. Idrogo-Córdova

Subjects
Laser ablation, Materials science, Analytical chemistry, Physics::Optics, General Physics and Astronomy, Nanoparticle, equipment and supplies, Laser, Electronic, Optical and Magnetic Materials, law.invention, Condensed Matter::Soft Condensed Matter, Geophysics, History and Philosophy of Science, Dynamic light scattering, Colloidal gold, law, Zeta potential, Physical and Theoretical Chemistry, Inductively coupled plasma, Spectroscopy
Abstract

The effect of magnetic field of 0.3 T on the concentration, distribution of sizes in suspension and zeta potential of colloidal gold and colloidal silver nanoparticles, obtained by considering the pulsed laser ablation in double distilled water was studied. The magnetic field was transverse to the direction of incidence of the laser radiation and parallel to the surface of a submerged target. An Nd: YAG laser was used (1064 nm in wavelength, 10 ns in duration, repetition rate of 10 Hz and 37 mJ of energy) to ablate targets. The colloids were characterized by inductively coupled plasma optical emission spectroscopy, ultraviolet-visible spectroscopy, dynamic light scattering and zeta potential. Concentration analysis suggested that applying magnetic field of 0.3 T during nanoparticle synthesis leads to higher concentration. Applying magnetic field led to an eleven percent increase in the concentration of the colloid with gold nanoparticles and a five percent increase in the concentration of the colloidal silver nanoparticles. The absorption spectra suggested the presence of spherical nanoparticles. When analyzing the effect of the magnetic field on the hydrodynamic size distribution of the nanoparticles and the zeta potential of the colloids, no significant changes were evidenced. The magnetic confinement of the plasma induced by laser ablation caused changes in the characteristics of the colloids.

Published
2021

12. Testing the discrepancy between actual and ideal body image with the Implicit Relational Assessment Procedure (IRAP)

Author

Mónica Hernández-López, Lourdes Quiñones-Jiménez, Miguel Rodríguez-Valverde, and Alberto L. Blanco-Romero

Subjects
genetic structures, RC435-571, 050109 social psychology, Overweight, 050105 experimental psychology, Behavioral Neuroscience, Implicit relational assessment procedure, Rating scale, Intervention (counseling), IRAP, medicine, Gender differences, 0501 psychology and cognitive sciences, Disordered eating, Implicit attitudes, Psychiatry, Nutrition and Dietetics, Body dissatisfaction, 05 social sciences, medicine.disease, Figural drawings, Psychiatry and Mental health, Distress, Eating disorders, Body image, Implicit attitude, medicine.symptom, Willingness to accept, Psychology, Social psychology, Research Article
Abstract

Background The discrepancy between actual and ideal body image is considered an index of body dissatisfaction and a risk factor for eating disorders. While discrepancy has been traditionally tested with figural drawing rating scales, in recent times the use of implicit measures has been explored. Methods This study employs the Implicit Relational Assessment Procedure (IRAP) to examine actual-ideal body-size discrepancy in a sample of 130 Spanish college students, as well as its utility to predict symptoms of eating disorders and other body-image relevant measures. Participants completed the Contour Drawing Rating Scale (CDRS). The three smallest and the three largest contour drawings of the CDRS were used as target stimuli in two different IRAP tasks: one in combination with the sample phrases “I am” and “I am not” (that assessed implicit actual body image), another in combination with the phrases “I want to be” and “I don’t want to be” (that assessed implicit ideal body image). After completing both IRAP tasks, participants completed explicit measures of body-image psychological inflexibility, body dissatisfaction, and symptoms of eating disorders. Results Results showed a small implicit bias towards thinness. Participants were faster in affirming than denying that they are thin and that they desire to be thin. They were also faster in affirming than denying that they are fat and that they want to be fat, but to a smaller extent than with thinness. Specifically, the implicit desire to be (or not be) fat emerged as an independent predictor of eating disorder symptoms, psychological inflexibility, and body dissatisfaction that significantly increased the predictive power of CDRS scores. Conclusions These findings underscore the need for further research on specific body image implicit beliefs towards fatness, both in subclinical and clinical populations, in order to examine whether willingness to accept the idea that one can have a larger body size can be a suitable target for prevention and intervention in eating disorders., Plain English summary Body dissatisfaction can be thought of as the discrepancy between actual and desired body size. This is typically measured with rating scales depicting a series of body silhouettes of increasing size, from extreme thinness to fatness. Respondents mark the points that match their current body size and the one they would ideally like to be (the more distance between both, the more body dissatisfaction). Like all self-reports, these scales are liable to self-presentation biases. Experimental procedures that require respondents to answer under time pressure (implicit measures) tap into more automatic reactions that are less amenable to deliberate manipulation. This study used one such procedure (the IRAP) to examine how rapidly participants identified themselves (or not) with pictures of underweight or overweight, and how rapidly they expressed a desire to be (or not) like such pictures. Participants did not show a clear discrepancy between their actual and their ideal body size with the IRAP. However, automatic reactions indicative of acceptance/rejection of the idea of becoming fatter, predicted the degree of body image distress as measured with different instruments. Unwillingness to accept this idea was associated with more severe symptoms of disordered eating.

Published
2021

13. The Role of Psychological Inflexibility and Experiential Approach on Mental Health in Children and Adolescents: An Exploratory Study

Author

Gloria Torres-Fernández, Miguel Rodríguez-Valverde, Salvador Reyes-Martín, and Mónica Hernández-Lopez

Subjects
Behavioral Neuroscience, Genetics, psychological inflexibility, experiential approach, emotional intelligence, mental health, children, Development, General Psychology, Ecology, Evolution, Behavior and Systematics
Abstract

The prevalence of mental health problems during childhood and adolescence is on the rise. There is a growing interest in the examination of personal variables that may function as risk factors and that may be targeted for effective intervention. This study explores the relationships amongst different aspects of psychological inflexibility (one, typically studied, focusing on the individual’s responding to unwanted emotions and cognitions, and another, more recently explored, focusing on the individual’s responding to desired thoughts and affective states), emotional intelligence, and mental health symptoms. A total of 129 school-going children (mean age: 11.16 years old) completed a battery of instruments comprising the Avoidance and Fusion Questionnaire-Youth (AFQ-Y17), the Experiential Approach Scale (EAS), the Emotional Intelligence Quotient Inventory (EQi-YV), and the Revised Child Anxiety and Depression Scale (RCADS-30). Results showed that both the AFQ-Y17 score and an EAS subscale score (Anxious Clinging) were significant independent predictors of mental health symptoms in general. Emotional intelligence was predictive only for depression, and both the AFQ-Y17 and the Anxious Clinging EAS subscale significantly incremented the predictive power of a hierarchical linear regression model including all three variables. These results underscore the relevance of psychological inflexibility for child/adolescent mental health, and the need to further explore a specific aspect of inflexibility regarding positive emotions and other appetitive private events.

Published
2022

14. MORFOLOGIA, COMPOSICIÓN Y ESTRUCTURA DE LAS FIBRAS DE UN TEXTIL DE LA CULTURA CHIMU

Author

Miguel A. Valverde-Alva, Jhenry F. Agreda-Delgado, Wilder Aldama-Reyna, Luis M. Angelats-Silva, Guillermo Gayoso-Bazán, Henry León-León, Fredy R. Pérez-Azahuanche, and Santiago A. Vásquez-García

Subjects
cultura Chimú, Geophysics, Chimú fibers, History and Philosophy of Science, Chimú textiles, fibras, General Physics and Astronomy, textil Chimú, algodón, Physical and Theoretical Chemistry, cotton, Electronic, Optical and Magnetic Materials, Chimú culture
Abstract

In this work, we studied the microfibers of a textile (T-shirt) of the Chimú culture. This culture developed on the northern coast of Peru. To determine the raw material and structural quality of the microfibers, the results of the Chimú textile were compared with the corresponding results for the microfibers of cotton from the northern coast of Peru (native cotton). Scanning electron microscopy images revealed that the Chimú textile yarns are composed of a set of interwoven microfibers. Energy-dispersive X-ray spectroscopy and pulsed laser-induced plasma spectroscopy techniques allowed the identification of characteristic cellulose atoms in the microfibers of Chimú textile and native cotton. Only for the Chimú textile, these spectroscopic techniques allowed the identification of atoms corresponding to natural dyes and powder residues. Attenuated total reflection Fourier transform infrared spectroscopy identified the same molecular bonds for the microfibers of Chimú textile and native cotton. For the microfibers of Chimú textile and native cotton, the X-ray diffractograms showed peaks characteristic of the cellulose Ig polymorphism of monoclinic P21 structure. The raw material of the Chimú textile is cotton and the microfibers of this material show significant structural stability. Resumen En este trabajo se estudiaron las microfibras de un textil (camiseta) de la cultura Chimú. Esta cultura se desarrolló en la costa norte del Perú. Para determinar la materia prima y calidad estructural de las microfibras, los resultados del textil Chimú fueron comparados con los correspondientes para las microfibras del algodón de la costa norte del Perú (algodón nativo). Las imágenes de microscopia electrónica de barrido revelaron que los hilos del textil Chimú están compuestos por un conjunto de microfibras entrelazadas. Las técnicas de espectroscopia de rayos X por energía dispersiva y de plasmas inducidos por laser permitieron identificar átomos característicos de la celulosa en las microfibras del textil Chimú y del algodón nativo. Únicamente para el textil Chimú, estas técnicas espectroscópicas permitieron identificar átomos que corresponderían a tintes naturales y a residuos de polvo. La espectroscopia de infrarrojo con transformada de Fourier por reflexión total permitió identificar los mismos enlaces moleculares para las microfibras del textil Chimú y del algodón nativo. Para las microfibras del textil Chimú y del algodón nativo, los difractogramas de rayos X mostraron picos característicos del polimorfismo de la celulosa Iß de estructura monoclínica P21. La materia prima del textil Chimú es el algodón y las microfibras del mismo presentan una significativa estabilidad estructural.

Published
2022

15. Surgical acute abdomen and COVID-19 vaccination

Author

Jose María, Rodríguez Lucas, Antonio José, Fernández López, Francisco Miguel, González Valverde, María Encarnación, Tamayo Rodríguez, and Antonio, Albarracín Marín-Blázquez

Subjects
Abdomen, Acute, COVID-19 Vaccines, Abdomen, Vaccination, COVID-19, Humans, Appendicitis
Abstract

In response to the publication "Acute appendicitis, foreign bodies and COVID-19 vaccination: correspondence", we reviewed the association between acute surgical abdomen and COVID-19 vaccination.

Published
2022

16. Online ACT intervention for fibromyalgia: An exploratory study of feasibility and preliminary effectiveness with smartphone-delivered experiential sampling assessment

Author

Pablo de la Coba, Miguel Rodríguez-Valverde, and Mónica Hernández-López

Subjects
Health Informatics
Abstract

Acceptance and commitment therapy (ACT) is an effective treatment for chronic pain conditions. ACT seeks to produce clinical change by enhancing Psychological Flexibility (PF). This exploratory (feasibility and preliminary effectiveness) study presents a pilot application of an online ACT group intervention for fibromyalgia (FM) with an extensive Experiential Sampling (ES) assessment of outcome and process variables via smartphone.5-weekly ACT online group sessions were applied to 9 female FM patients. Questionnaire-based assessments of several clinical outcomes and PF processes were conducted pre- and post-intervention, and at 6-month follow-up. Extensive (6 weeks pre- and 6 weeks post-intervention) smartphone-delivered ES was implemented to gather process and outcome data in the patients' usual contexts. Clinically significant change was evaluated both at the group level and individually.This treatment format appears to be feasible and acceptable to participants, with good adoption and completion rates (75 %) and excellent rates of treatment completion and clinical adherence (100 %). Participants showed significant reductions in affective pain, distress and biopsychosocial impact of FM both post-intervention and at 6-month follow-up (as measured with questionnaires), as well as significant improvements in satisfaction with actions and emotional discomfort (as measured through ES). Multilevel regression analyses indicated that PF-related processes assessed through ES had a significant impact on clinical outcomes and predicted the impact of FM at the 6-month follow-up.A brief online group ACT intervention for FM was both feasible and acceptable to participants. Also, there was preliminary evidence of effectiveness in enhancing pain-related PF and producing clinical benefits in FM.

Published
2022

17. Idiopathic myointimal hyperplasia of the mesenteric veins, an uncommon cause of intestinal ischemia

Author

Pedro López Morales, Francisco Miguel González Valverde, Clara Giménez Francés, Francisco Pastor Quirante, and Antonio Albarracín Marín-Blázquez

Subjects
Hyperplasia, Mesenteric Veins, Ischemia, Gastroenterology, Humans, General Medicine
Abstract

Idiopathic myointimal hyperplasia of the mesenteric veins (IMHMV) is an uncommon cause of intestinal ischemia. It was firstly described by Genta and Haggit in 1991. Only a few cases have been reported and it is difficult to know the true incidence.

Published
2022

18. Structural determinants of TRPV4 inhibition and identification of new antagonists with antiviral activity

Author

Gemma Pérez-Vilaró, Miguel A. Valverde, Pablo Doñate-Macian, Fanny Rubio-Moscardo, Yorley Duarte, Jonathan Canan, Fernando D. González-Nilo, and Juana Díez

Subjects
0301 basic medicine, TRPV4, Xenopus, In silico, TRPV Cation Channels, Computational biology, Molecular dynamics, Antiviral Agents, drug discovery, 03 medical and health sciences, Transient receptor potential channel, Transient Receptor Potential Channels, 0302 clinical medicine, Animals, Humans, structure, Antiviral, Binding site, Inhibition, Pharmacology, Virtual screening, Binding Sites, Zika Virus Infection, Drug discovery, HC067047, Chemistry, Structure, Zika Virus, RN1734, antiviral, Small molecule, inhibition, molecular dynamics, 030104 developmental biology, in silico, Docking (molecular), 030217 neurology & neurosurgery
Abstract

Background and purpose: The transient receptor potential vanilloid 4 (TRPV4) cation channel participates in multiple physiological processes and is also at the core of different diseases, making this channel an interesting pharmacological target with therapeutic potential. However, little is known about the structural elements governing its inhibition. Experimental approach: We have now combined in silico drug discovery and molecular dynamics simulation based on Xenopus tropicalis xTRPV4 structure with functional studies measuring cell Ca2+ influx mediated by human TRPV4 channel to characterize the binding site of known TRPV4 inhibitors and to identify novel small molecule channel modulators. Key results: We have found that the inhibitor HC067047 binds to a pocket conformed by residues from S2-S3 linker (xTRPV4-D542), S4 (xTRPV4-M583 and Y587 and S5 (xTRPV4-D609 and F613). This pocket was also used for structure-based virtual screening in the search of novel channel modulators. Forty potential hits were selected based on the lower docking scores (from ~250,000 compounds) and their effect upon TRPV4 functionally tested. Three were further analysed for stability using molecular dynamics simulation and functionally tested on TRPV4 channels carrying mutations in the binding pocket. Compound NSC151066, shown to require residue xTRPV4-M583 for its inhibitory effect, presented an IC50 of 145 nM and demonstrated to be an effective antiviral against Zika virus with a potency similar to HC067047. Conclusion and implications: Together, we propose structural insights into the inhibition of TRPV4 and how this information can be used for the design of novel channel modulators. We thank Dr. Andres Merits (University of Tartu, Estonia) for kindly providing the plasmid encoding the ZIKV with NanoLuc, Spanish Ministry of Economy and Competitiveness through grants RTI2018‐099718 (to M.A.V.) and BFU2016‐80039‐R (to J.D.), an institutional “Unidad de Excelencia María de Maeztu” CEX2018‐000792‐M and FEDER funds. F.G.‐N. thanks Fondecyt Regular projects 1170733, the US Army of USA, W911NF‐14‐1‐0520 and The Centro Interdisciplinario de Neurociencia de Valparaíso is a Millennium Institute supported by the Millennium Scientific Initiative of the Ministerio de Economía, Fomento y Turismo P029‐022‐F.

Published
2020

19. Extracellular fluid viscosity enhances cell migration and cancer dissemination

Author

Kaustav Bera, Alexander Kiepas, Inês Godet, Yizeng Li, Pranav Mehta, Brent Ifemembi, Colin D. Paul, Anindya Sen, Selma A. Serra, Konstantin Stoletov, Jiaxiang Tao, Gabriel Shatkin, Se Jong Lee, Yuqi Zhang, Adrianna Boen, Panagiotis Mistriotis, Daniele M. Gilkes, John D. Lewis, Chen-Ming Fan, Andrew P. Feinberg, Miguel A. Valverde, Sean X. Sun, and Konstantinos Konstantopoulos

Subjects
Cancer microenvironment, Multidisciplinary, Sodium-Hydrogen Exchangers, Lung Neoplasms, Viscosity, TRPV Cation Channels, Extracellular Fluid, Breast Neoplasms, Chick Embryo, Actins, Actin-Related Protein 2-3 Complex, Mice, Cell Movement, Neoplasms, Spheroids, Cellular, Animals, Cell migration, Hippo Signaling Pathway, Neoplasm Metastasis, rhoA GTP-Binding Protein, Lung, Zebrafish
Abstract

Data de publicació electrònica: 02-11-2022 Cells respond to physical stimuli, such as stiffness1, fluid shear stress2 and hydraulic pressure3,4. Extracellular fluid viscosity is a key physical cue that varies under physiological and pathological conditions, such as cancer5. However, its influence on cancer biology and the mechanism by which cells sense and respond to changes in viscosity are unknown. Here we demonstrate that elevated viscosity counterintuitively increases the motility of various cell types on two-dimensional surfaces and in confinement, and increases cell dissemination from three-dimensional tumour spheroids. Increased mechanical loading imposed by elevated viscosity induces an actin-related protein 2/3 (ARP2/3)-complex-dependent dense actin network, which enhances Na+/H+ exchanger 1 (NHE1) polarization through its actin-binding partner ezrin. NHE1 promotes cell swelling and increased membrane tension, which, in turn, activates transient receptor potential cation vanilloid 4 (TRPV4) and mediates calcium influx, leading to increased RHOA-dependent cell contractility. The coordinated action of actin remodelling/dynamics, NHE1-mediated swelling and RHOA-based contractility facilitates enhanced motility at elevated viscosities. Breast cancer cells pre-exposed to elevated viscosity acquire TRPV4-dependent mechanical memory through transcriptional control of the Hippo pathway, leading to increased migration in zebrafish, extravasation in chick embryos and lung colonization in mice. Cumulatively, extracellular viscosity is a physical cue that regulates both short- and long-term cellular processes with pathophysiological relevance to cancer biology. This work was supported in part by R01 CA257647 (to K.K. and D.M.G.), R01 GM134542 (to S.X.S. and K.K.), NSF 2045715 (to Y.L.), R01 AR071976 (to C.-M.F. and J.T.), R01 AR072644 (to C.-M.F. and J.T.) and R01 CA054358 (to A.P.F.), the Spanish Ministry of Science, Education and Universities through grants RTI2018 099718-B-100 (to M.A.V.) and an institutional “Maria de Maeztu” Programme for Units of Excellence in R&D and FEDER funds (to M.A.V.), and postdoctoral fellowships from the Fonds de recherche du Quebec—Nature et technologies and the Natural Sciences and Engineering Research Council of Canada (to A.K.). The opinions, findings and conclusions, or recommendations expressed are those of the authors and do not necessarily reflect the views of any of the funding agencies.

Published
2022

20. Polarized NHE1 and SWELL1 regulate migration direction, efficiency and metastasis

Author

Yuqi Zhang, Yizeng Li, Keyata N. Thompson, Konstantin Stoletov, Qinling Yuan, Kaustav Bera, Se Jong Lee, Runchen Zhao, Alexander Kiepas, Yao Wang, Panagiotis Mistriotis, Selma A. Serra, John D. Lewis, Miguel A. Valverde, Stuart S. Martin, Sean X. Sun, and Konstantinos Konstantopoulos

Subjects
Sodium-Hydrogen Exchangers, Multidisciplinary, Water, General Physics and Astronomy, General Chemistry, General Biochemistry, Genetics and Molecular Biology, Cell invasion, Metastasis, Breast cancer, Cell Movement, Neoplasms, Cell polarity, Humans, Cell Size
Abstract

Cell migration regulates diverse (patho)physiological processes, including cancer metastasis. According to the Osmotic Engine Model, polarization of NHE1 at the leading edge of confined cells facilitates water uptake, cell protrusion and motility. The physiological relevance of the Osmotic Engine Model and the identity of molecules mediating cell rear shrinkage remain elusive. Here, we demonstrate that NHE1 and SWELL1 preferentially polarize at the cell leading and trailing edges, respectively, mediate cell volume regulation, cell dissemination from spheroids and confined migration. SWELL1 polarization confers migration direction and efficiency, as predicted mathematically and determined experimentally via optogenetic spatiotemporal regulation. Optogenetic RhoA activation at the cell front triggers SWELL1 re-distribution and migration direction reversal in SWELL1-expressing, but not SWELL1-knockdown, cells. Efficient cell reversal also requires Cdc42, which controls NHE1 repolarization. Dual NHE1/SWELL1 knockdown inhibits breast cancer cell extravasation and metastasis in vivo, thereby illustrating the physiological significance of the Osmotic Engine Model. This work was supported, in part, by an NIH/NCI R01 CA254193 (K.K., S.S.M., and S.X.S.), R01 GM134542 (S.X.S. and K.K.), NSF 2045715 (Y.L.), the Spanish Ministry of Science, Education and Universities through grants RTI2018-099718-B-100 (M.A.V.), an institutional “Maria de Maeztu” Programme for Units of Excellence in R&D and FEDER funds (M.A.V.), and postdoctoral fellowships from the Fonds de recherche du Quebec—Nature et technologies and the Natural Sciences and Engineering Research Council of Canada (A.K.). The opinions, findings, and conclusions, or recommendations expressed are those of the authors and do not necessarily reflect the views of any of the funding agencies.

Published
2022

22. Surgical acute abdomen and COVID-19 vaccination

Author

Jose María Rodríguez Lucas, Antonio José Fernández López, Francisco Miguel González Valverde, María Encarnación Tamayo Rodríguez, and Antonio Albarracín Marín-Blázquez

Subjects
Gastroenterology, General Medicine
Published
2022

23. MAVEN/NGIMS Thermospheric Neutral Wind Observations: Interpretation Using the M‐GITM General Circulation Model

Author

Stephen W. Bougher, Mehdi Benna, Dave J. Pawlowski, K. Roeten, Yuni Lee, Francisco Gonzalez-Galindo, Miguel Lopez-Valverde, Paul R. Mahaffy, National Aeronautics and Space Administration (US), and Consejo Superior de Investigaciones Científicas (España)

Subjects
010504 meteorology & atmospheric sciences, Meteorology, Mars, MAVEN, GCM transcription factors, GCM, 01 natural sciences, Planetary Data System, Geophysics, Space and Planetary Science, Geochemistry and Petrology, Research council, General Circulation Model, NGIMS, Earth and Planetary Sciences (miscellaneous), Thermospheric winds, Environmental science, Space Science, Deep blue, 0105 earth and related environmental sciences
Abstract

NGIMS data sets used in this paper are available on the Planetary Data System (http://pds-atmospheres.nmsu.edu/data_ and_services/atmospheres_data/MAVEN/ngims.html) as well as EUV data sets (https://pds-ppi.igpp.ucla.edu/search/view/?f=yes&id=pds://PPI/maven.euv.modelled). Data cubes containing M-GITM simulations used in this paper can be found on the University of Michigan Deep Blue repository (http://doi.org/10.7302/85qt-e980)., Using a new observational technique, the NGIMS (Neutral Gas and Ion Mass Spectrometer) instrument on the MAVEN (Mars Atmosphere and Volatile Evolution) spacecraft has the unique capability to measure horizontal thermospheric winds. Measured along the orbit track from periapsis (∼150 km) to ∼200 km, these are the first in situ observations of thermospheric winds at Mars. Significantly, this also means that simulated winds from a global circulation model can be compared to in situ observations from this part of the Martian atmosphere for the first time. In this study, observations from five NGIMS neutral wind campaigns have been compared to simulations from the Mars Global Ionosphere-Thermosphere Model (M-GITM), a ground to exosphere 3-D general circulation model. By comparing NGIMS neutral wind observations to model simulations, the processes driving the winds and their variations in the upper atmosphere are examined. These comparisons show that for certain observational periods, the M-GITM simulated winds can generally replicate the magnitude and/or direction of the NGIMS wind observations, while in others, significant differences occur. In general, wind observations from NGIMS campaigns with large orbit-to-orbit variability are not well replicated by M-GITM, while campaigns with higher observed wind speeds are better captured by the model. Additionally, using these data-model comparisons, the relative role of normal solar forcing and corresponding differential heating in driving thermospheric winds at Mars is found to be variable, likely acting as the primary driver under some conditions and secondary to other physical processes under others.©2019. American Geophysical Union. All Rights Reserved., Funding support for this research was provided by the MAVEN project, Grant NNH10CC04C. This work was also supported by NASA Headquarters under the NASA Earth and Space Science Fellowship Program - Grant 80NSSC18K1238. Funding for F. Gonzalez-Galindo and M. A. Lopez-Valverde was provided by the Spanish National Research Council under intramural project CSIC 201450E022

Published
2019

24. First Detection and Thermal Characterization of Terminator CO 2 Ice Clouds With ExoMars/NOMAD

Author

Stephen R. Lewis, Aurélien Stolzenbach, Manish R. Patel, Loïc Trompet, Jose-Juan Lopez-Moreno, Ian Thomas, Matteo Crismani, Ann Carine Vandaele, S. Aoki, Giuliano Liuzzi, Arianna Piccialli, Lori Neary, Frank Daerden, Geronimo L. Villanueva, R. Todd Clancy, Michael D. Smith, Bojan Ristic, Giancarlo Bellucci, Miguel Lopez-Valverde, Belgian Science Policy Office, European Space Agency, UK Space Agency, European Commission, Ministerio de Economía y Competitividad (España), and Ministerio de Ciencia e Innovación (España)

Subjects
010504 meteorology & atmospheric sciences, Terminator (solar), Mars Exploration Program, 01 natural sciences, Trace gas, law.invention, Astrobiology, Atmosphere, Orbiter, Geophysics, 13. Climate action, law, Middle latitudes, 0103 physical sciences, General Earth and Planetary Sciences, Precipitation, 010303 astronomy & astrophysics, Geology, Nadir (topography), 0105 earth and related environmental sciences
Abstract

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made., We present observations of terminator CO2 ice clouds events in three groups: Equatorial dawn, Equatorial dusk (both between 20°S and 20°N) and Southern midlatitudes at dawn (45°S and 55°S east of Hellas Basin) with ESA ExoMars Trace Gas Orbiter's Nadir and Occultation for MArs Discovery instrument. CO2 ice abundance is retrieved simultaneously with water ice, dust, and particle sizes, and rotational temperature and CO2 column profiles in 16 of 26 cases. Small particles (, ExoMars is a space mission of the European Space Agency (ESA) and Roscosmos. The NOMAD experiment is led by the Royal Belgian Institute for Space Aeronomy (IASB-BIRA), assisted by Co-PI teams from Spain (IAA-CSIC), Italy (INAF-IAPS), and the United Kingdom (Open University). This project acknowledges funding by the Belgian Science Policy Office (BELSPO), with the financial and contractual coordination by the ESA Prodex Office (PEA 4000103401, 4000121493), by the Spanish MICINN through its Plan Nacional and by European funds under grants PGC2018-101836-B-I00 and ESP2017-87143-R (MINECO/FEDER), as well as by UK Space Agency through grants ST/V002295/1, ST/V005332/1, ST/R001405/1 and ST/S00145X/1 and Italian Space Agency through grant 2018-2-HH.0. The IAA/CSIC team acknowledges financial support from the State Agency for Research of the Spanish MCIU through the “Center of Excellence Severo Ochoa” award for the Instituto de Astrofísica de Andalucía (SEV-2017-0709). This work was supported by NASA's Mars Program Office under WBS 604796, “Participation in the TGO/NOMAD Investigation of Trace Gases on Mars” and by NASA's SEEC initiative under Grant Number NNX17AH81A, “Remote sensing of Planetary Atmospheres in the Solar System and Beyond”. This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 101004052. U.S. investigators were supported by the National Aeronautics and Space Administration.

Published
2021

25. Spanish Adaptation of the Experiential Approach Scale (EAS)

Author

Salvador Reyes-Martín, Mónica Hernández-López, and Miguel Rodríguez-Valverde

Subjects
Male, Psychometrics, psychological inflexibility, experiential avoidance, experiential approach, acceptance and commitment therapy, EAS, Health, Toxicology and Mutagenesis, Emotions, Public Health, Environmental and Occupational Health, Reproducibility of Results, Anxiety, Article, Surveys and Questionnaires, Quality of Life, Medicine, Humans, Female
Abstract

Psychological inflexibility is a transdiagnostic dimension associated to psychological distress and poor mental health and quality of life. While multiple instruments have been developed for the assessment of patterns of inflexible responding to aversive private events (e.g., unwanted cognitions and emotions), the Experiential Approach Scale (EAS) is the first instrument specifically designed to assess inflexible responding to appetitive private events (e.g., desired affective states). In this study, we explored the factor structure, internal consistency, and convergent validity of a Spanish adaptation of the EAS with a convenience sample of college students from Spain (n = 206; 79% female). A two-factor solution demonstrated very good fit to the data and was similar to the original two-subscale EAS structure: Anxious Clinging and Experience Prolonging. The scale showed adequate overall (α = 0.85) and subscale (αs: 0.90 and 0.89) internal consistency. Unlike the original instrument, both subscales were uncorrelated. Anxious Clinging correlated positively with experiential avoidance and with measures of negative affect and psychopathology, and negatively with positive affect, subjective happiness, and life satisfaction. In turn, Experience Prolonging correlated negatively with psychopathology and positively with positive affect, subjective happiness, and life satisfaction. Our results point to Anxious Clinging as the only EAS subscale contributing to psychological inflexibility.

Published
2021

26. The mechanosensitive Piezo1 channel controls endosome trafficking for an efficient cytokinetic abscission

Author

Miguel A. Valverde, Selma A. Serra, Fanny Rubio-Moscardo, Covadonga F. Hevia, Cristina Pujades, Marina Vogel-González, Julia Carrillo-Garcia, Pablo Doñate-Macian, and Víctor Herrera-Fernández

Subjects
Multidisciplinary, Abscission, Cell division, Endosome, PIEZO1, SciAdv r-articles, Mechanosensitive channels, Biomedicine and Life Sciences, Cell Biology, Biology, Cytokinesis, Cell biology, Research Article
Abstract

Description, Piezo1 transduces mechanical forces at the intercellular bridge to coordinate the machinery necessary to split dividing cells., Mechanical forces are exerted throughout cytokinesis, the final step of cell division. Yet, how forces are transduced and affect the signaling dynamics of cytokinetic proteins remains poorly characterized. We now show that the mechanosensitive Piezo1 channel is activated at the intercellular bridge (ICB) connecting daughter cells to regulate abscission. Inhibition of Piezo1 caused multinucleation both in vitro and in vivo. Piezo1 positioning at the ICB during cytokinesis depends on Pacsin3. Pharmacological and genetic inhibition of Piezo1 or Pacsin3 resulted in mislocation of Rab11-family-interacting protein 3 (Rab11-FIP3) endosomes, apoptosis-linked gene 2-interacting protein X (ALIX), and endosomal sorting complex required for transport III (ESCRT-III). Furthermore, we identified FIP3 as the link between Piezo1-generated Ca2+ signals and ALIX delivery to the ICB, where ALIX recruits the ESCRT-III component charged multivesicular body protein 4B, which promotes abscission. These results provide a different view of how mechanical forces participate in cytokinesis and identify Piezo1 as a key modulator of endosome trafficking.

Published
2021

27. Apendicitis del muñón

Author

Lucía Sánchez-Alonso, Francisco Miguel González-Valverde, and Pedro López-Morales

Subjects
Gynecology, medicine.medical_specialty, Hepatology, business.industry, Gastroenterology, Medicine, business
Published
2022

28. The Martian environment observed by NOMAD on ExoMars Trace Gas Orbiter

Author

Ann Carine Vandaele, Frank Daerden, Ian R. Thomas, Shohei Aoki, Cédric Depiesse, Justin Erwin, Lori Neary, Arianna Piccialli, Bojan Ristic, Séverine Robert, Loïc Trompet, Sébastien Viscardy, Yannick Willame, Jean-Claude Gérard, Geronimo Villanueva, Jon Mason, Manish Patel, Giancarlo Bellucci, Miguel Lopez-Valverde, and Jose-Juan Lopez-Moreno

Abstract

The NOMAD (“Nadir and Occultation for MArs Discovery”) spectrometer suite on board the ExoMars Trace Gas Orbiter has been designed to investigate the composition of Mars' atmosphere, with a particular focus on trace gases, clouds and dust. The instrument probes the ultraviolet and infrared regions covering large parts of the 0.2-4.3 µm spectral range [1,2], with 3 spectral channels: a solar occultation channel (SO – Solar Occultation; 2.3–4.3 μm), a second infrared channel capable of nadir, solar occultation, and limb sounding (LNO – Limb Nadir and solar Occultation; 2.3–3.8 μm), and an ultraviolet/visible channel (UVIS – Ultraviolet and Visible Spectrometer, 200–650 nm). Since its arrival at Mars in April 2018, NOMAD performed solar occultation, nadir and limb observations dedicated to the determination of the composition and structure of the atmosphere.NOMAD has been accumulating data about the Martian atmosphere and its surface since its insertion. We will present some results covering the atmosphere composition including clouds and dust, climatologies of water, carbon monoxide and ozone. We also report on the different discoveries highlighted by the instrument by pointing to a series of contributions to this conference that will present in detail several specific studies, like recent progress in the instrument calibration, the latest CO2 and temperature vertical profiles, studies of aerosol nature and distribution, water vapor profiles and variability, carbon monoxide vertical distribution, dayglow observations; detection of HCl, its vertical profiles and in general advances in the analysis of the spectra recorded by the three channels of NOMAD.References[1] Vandaele, A.C., et al., 2015. Planet. Space Sci. 119, 233-249.[2] Vandaele et al., 2018. Space Sci. Rev., 214:80, doi.org/10.1007/s11214-11018-10517-11212.

Published
2021

29. Calibration of the Nomad SO Channel on ExoMars Trace Gas Orbiter

Author

Ian Thomas, Shohei Aoki, Loic Trompet, Justin Erwin, Geronimo Villanueva, Giuliano Liuzzi, Miguel Lopez-Valverde, Adrian Brines, Bernd Funke, Ann Carine Vandaele, Severine Robert, Frank Daerden, Bojan Ristic, Jose Juan Lopez-Moreno, Giancarlo Bellucci, and Manish Patel

Abstract

Introduction NOMAD is a three-channel spectrometer on the ExoMars 2016 Trace Gas Orbiter. The NOMAD solar occultation (SO) channel has been operating around Mars since April 2018 [1]. In the past three years of science operations, we have performed many calibrations and have taken millions of spectra. This huge dataset allows us to continue to refine the calibration, through additional characterisation of the optical elements, detector performance and temperature-induced effects. SO channel By using an Acousto-Optic Tunable Filter (AOTF) in combination with an echelle grating spectrometer, the SO channel is able to operate at unprecedented spectral resolution – typically 0.15 to 0.25 cm-1 [2] – and is therefore able to measure trace gases and set stringent upper limits on the presence (or non-presence) of organic molecules in the Martian atmosphere [3]. In solar occultation mode, the Sun is used as the illumination source, meaning that very high Signal-to-Noise Ratios (SNRs) can be achieved, typically up to 2,000 for a single spectrum at the top of the atmosphere. The SO channel records 24 spectra per second in solar occultation mode, with a typical vertical sampling resolution (i.e. altitude difference between consecutive spectra) of around 50-150m [4]. Therefore, by binning multiple spectra together, the SNR can be increased significantly whilst still keeping a high vertical sampling resolution. Calibration However the AOTF-grating combination also presents additional challenges, as the optical properties of both elements must be independently characterised in order to correctly retrieve atmospheric gas concentrations. Analysis of the AOTF shape and sidelobes, and the Instrument Line Shape (ILS), are ongoing in several of the groups within the NOMAD team. Additional systematic effects have also been identified in the spectra e.g. [5] which hamper efforts to further increase SNR and thus reduce detection limits via binning. Whilst much calibration work on this has already been performed [2, 4], the calibration can still be improved and work is ongoing to understand these effects and how to remove them from the data. Applications Since the beginning of the mission, a particular emphasis has been placed on making observations of CH4 around Gale Crater, in both nadir and solar occultation modes. HCl detections observations are now also made regularly, following the discovery of HCl in the atmosphere [7, 8] and its isotopologue [5], which are close to the detection limit of the channel. Calibration improvements will allow us to further constrain the CH4 upper detection limit, observe lower concentrations of HCl, and further constrain the isotopic ratio. References [1] Vandaele, A. C. et al (2015) Planet. Space Sci., 119 ; [2] Liuzzi, G. et al. (2019) Icarus, 321 ; [3] Knutsen, E. W. et al. (2021), Icarus, 357 ; [4] Thomas, I. R. et al. (submitted 2021) “Calibration of NOMAD on ExoMars Trace Gas Orbiter: Part 1 – the SO channel”; [5] Liuzzi G. et al (2021) GRL 48(9); [6] Korablev, O. et al. (2021) Science Advances, 7(7); [8] Aoki, S. et al. (accepted 2021) “Annual appearance of hydrogen chloride on Mars and a striking similarity with the water vapor vertical distribution observed by TGO/NOMAD”, GRL.

Published
2021

30. Annual Appearance of Hydrogen Chloride on Mars and a Striking Similarity With the Water Vapor Vertical Distribution Observed by TGO/NOMAD

Author

Frank Daerden, Franck Lefèvre, Frédéric Schmidt, Ann Carine Vandaele, Alexander Trokhimovskiy, Frank Montmessin, James A. Whiteway, Giuliano Liuzzi, Ian Thomas, Sébastien Viscardy, Geronimo Villanueva, Justin Erwin, S. Aoki, Manish R. Patel, Jose-Juan Lopez-Moreno, Anna Fedorova, Oleg Korablev, R. T. Clancy, Bojan Ristic, Lori Neary, Giancarlo Bellucci, Miguel Lopez-Valverde, Séverine Robert, Loïc Trompet, Matteo Crismani, Kevin Olsen, Institute of Space and Astronautical Science (ISAS), Japan Aerospace Exploration Agency [Sagamihara] (JAXA), Belgian Institute for Space Aeronomy / Institut d'Aéronomie Spatiale de Belgique (BIRA-IASB), Laboratoire de Physique Atmosphérique et Planétaire (LPAP), Université de Liège, Institut de la matière condensée et des nanosciences / Institute of Condensed Matter and Nanosciences (IMCN), Université Catholique de Louvain = Catholic University of Louvain (UCL), NASA Goddard Space Flight Center (GSFC), Department of Physics [Washington], American University Washington D.C. (AU), California State University [San Bernardino] (CSUSB), Space Science Institute [Boulder] (SSI), Centre for Research in Earth and Space Science [Toronto] (CRESS), York University [Toronto], Géosciences Paris Saclay (GEOPS), Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Instituto de Astrofísica de Andalucía (IAA), Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), School of Physical Sciences [Milton Keynes], Faculty of Science, Technology, Engineering and Mathematics [Milton Keynes], The Open University [Milton Keynes] (OU)-The Open University [Milton Keynes] (OU), Space Science and Technology Department [Didcot] (RAL Space), STFC Rutherford Appleton Laboratory (RAL), Science and Technology Facilities Council (STFC)-Science and Technology Facilities Council (STFC), Istituto di Astrofisica e Planetologia Spaziali - INAF (IAPS), Istituto Nazionale di Astrofisica (INAF), Department of Physics [Oxford], University of Oxford [Oxford], PLANETO - LATMOS, Laboratoire Atmosphères, Milieux, Observations Spatiales (LATMOS), Sorbonne Université (SU)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Sorbonne Université (SU)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS), Space Research Institute of the Russian Academy of Sciences (IKI), Russian Academy of Sciences [Moscow] (RAS), European Space Agency. Grant Numbers: PEA 4000103401, 4000121493, European. Grant Number: PGC2018-101836-B-I00 and ESP2017-87143-R, Ministerio de Ciencia, Innovación y Universidades (España), Ministerio de Economía y Competitividad (España), European Commission, European Space Agency, Agenzia Spaziale Italiana, Fonds de la Recherche Scientifique (Fédération Wallonie-Bruxelles), Belgian Science Policy Office, National Aeronautics and Space Administration (US), and UK Space Agency

Subjects
geography, geography.geographical_feature_category, 010504 meteorology & atmospheric sciences, Atmosphere of Mars, Mars Exploration Program, 010502 geochemistry & geophysics, Atmospheric sciences, 01 natural sciences, Sink (geography), law.invention, Trace gas, chemistry.chemical_compound, Orbiter, Geophysics, chemistry, 13. Climate action, Dust storm, law, [SDU]Sciences of the Universe [physics], General Earth and Planetary Sciences, Environmental science, Hydrogen chloride, Water vapor, 0105 earth and related environmental sciences
Abstract

Hydrogen chloride (HCl) was recently discovered in the atmosphere of Mars by two spectrometers onboard the ExoMars Trace Gas Orbiter. The reported detection made in Martian Year 34 was transient, present several months after the global dust storm during the southern summer season. Here, we present the full data set of vertically resolved HCl detections obtained by the NOMAD instrument, which covers also Martian year 35. We show that the particular increase of HCl abundances in the southern summer season is annually repeated, and that the formation of HCl is independent from a global dust storm event. We also find that the vertical distribution of HCl is strikingly similar to that of water vapor, which suggests that the uptake by water ice clouds plays an important role. The observed rapid decrease of HCl abundances at the end of the southern summer would require a strong sink independent of photochemical loss. © 2021. American Geophysical Union., ExoMars is a space mission of the European Space Agency and Roscosmos. The NOMAD experiment is led by the Royal Belgian Institute for Space Aeronomy (IASB- BIRA), assisted by Co-PI teams from Spain (IAA-CSIC), Italy (INAF-IAPS), and the United Kingdom (Open University). This project acknowledges funding by the Belgian Science Policy Office, with the financial and contractual coordination by the European Space Agency Prodex Office (PEA 4000103401 and 4000121493), by the Spanish MICINN through its Plan Nacional and by European funds under grants PGC2018-101836-B-I00 and ESP2017-87143-R (MINECO/FEDER), as well as by UK Space Agency through grants ST/V002295/1, ST/V005332/1 ST/S00145X/1 ST/S00145X/1 and ST/T002069/1, and Italian Space Agency through grant 2018-2-HH.0. This work was supported by NASA's Mars Program Office under WBS 604796, "Participation in the TGO/NOMAD Investigation of Trace Gases on Mars." The IAA/CSIC team acknowledges financial support from the State Agency for Research of the Spanish MCIU through the "Center of Excellence Severo Ochoa" award for the Instituto de Astrofisica de Andalucia (SEV-2017-0709). This work was supported by the Belgian Fonds de la Recherche Scientifique-FNRS under grant numbers 30442502 (ET_HOME) and T.0171.16 (CRAMIC) and Belgian Science Policy Office BrainBe SCOOP and MICROBE Projects. S. A. is "Charge de Recherches" at the F.R.S.-FNRS. U.S. investigators were supported by the National Aeronautics and Space Administration. We acknowledge support from the Institut National des Sciences de l'Univers" (INSU), the "Centre National de la Recherche Scientifique" (CNRS) and "Centre National d'Etudes Spatiales" (CNES) through the "Programme National de Planetologie".

Published
2021

31. Pyometra secondary to colouterine fistula as a complication of diverticulitis

Author

Francisco Miguel González Valverde and María Jesús Gómez Ramos

Subjects
medicine.medical_specialty, Fistula, Colouterine fistula, business.industry, Urology, General surgery, Obstetrics and Gynecology, Pyometra, Diverticulitis, medicine.disease, Diverticular abscess, medicine, Humans, Female, Complication, business
Published
2020

32. Macrocystic serous cystadenoma of the pancreas

Author

Francisco Miguel González Valverde, Patricia Pastor Pérez, and Francisco Pastor Quirante

Subjects
medicine.medical_specialty, Hepatology, medicine.diagnostic_test, business.industry, Gastroenterology, Magnetic resonance imaging, Serous Cystadenoma, medicine.disease, medicine.anatomical_structure, X ray computed, Predictive value of tests, Cystadenoma, Medicine, Radiology, business, Pancreas
Published
2019

33. On the derivation of thermospheric temperatures from dayglow emissions on Mars

Author

Maya García-Comas, Miguel Lopez-Valverde, Sergio Jiménez-Monferrer, François Forget, Francisco Gonzalez-Galindo, Instituto de Astrofísica de Andalucía (IAA), Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), Laboratoire de Météorologie Dynamique (UMR 8539) (LMD), Institut national des sciences de l'Univers (INSU - CNRS)-École polytechnique (X)-École des Ponts ParisTech (ENPC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Département des Géosciences - ENS Paris, École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-École normale supérieure - Paris (ENS Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL), Ministerio de Ciencia, Innovación y Universidades (España), European Commission, Ministerio de Economía y Competitividad (España), and Ministerio de Ciencia e Innovación (España)

Subjects
010504 meteorology & atmospheric sciences, Solar zenith angle, Mars, Astrophysics, Ultraviolet observations, 01 natural sciences, 7. Clean energy, Global model, Atmosphere, Altitude, 0103 physical sciences, 010303 astronomy & astrophysics, ComputingMilieux_MISCELLANEOUS, 0105 earth and related environmental sciences, Physics, Aeronomy, Astronomy and Astrophysics, Scale height, Mars Exploration Program, On board, 13. Climate action, Space and Planetary Science, [SDU]Sciences of the Universe [physics]
Abstract

The Cameron bands and the UV doublet are two of the most prominent emission systems in the UV in Mars dayside. Their altitude variation has been exploited in the past to derive thermospheric temperatures from measurements obtained by the Mariner 6, 7, and 9 missions, the SPICAM instrument on board Mars Express, and the IUVS instrument on board MAVEN. Here we identify and quantify possible biases in these temperature determinations. For this purpose, we use a global model able to simulate these two emission systems, and we compare the temperature derived from the simulated emission with that predicted by the model at the same location and time. We find that an exponential fit to the scale height of the UV doublet can be used to derive temperatures with an error less than 10 K at altitudes above about 170 km and for low and moderate values of the Solar Zenith Angle. The temperature derived from the Cameron bands is biased towards higher values due to the non-negligible contribution of CO to the emission. We find that, at 170 km, the difference between the temperature derived from the Cameron bands and the UV doublet can be related to the CO abundance. Our results have implications for previous temperature determinations from the Mariners, SPICAM/MEx and IUVS/MAVEN, some of them being biased by about 25 K. © 2021 Elsevier Inc. All rights reserved., The IAA team acknowledges financial support from the Agencia Estatal de Investigacion (AEI) of the Spanish Ministerio de Ciencia, Innovacion y Universidades (MCIU) through the "Center of Excellence Severo Ochoa'' award to the Instituto de Astrofisica de Andalucia (SEV-2017-0709). FG-G and MALV are funded by the Spanish MCIU, the AEI, and EU FEDER funds under projects RTI2018-100920-J-I00 and PGC2018-101836-B-100, respectively.

Published
2021

34. Comprehensive investigation of Mars methane and organics with ExoMars/NOMAD

Author

Lori Neary, Ian Thomas, Geronimo L. Villanueva, Elise W. Knutsen, Justin Erwin, Frank Daerden, Shohei Aoki, Michael D. Smith, Matteo Crismani, Sébastien Viscardy, Loïc Trompet, Jose-Juan Lopez-Moreno, Özgür Karatekin, Miguel Lopez-Valverde, Ann Carine Vandaele, Giancarlo Bellucci, Bojan Ristic, Manish R. Patel, Giuliano Liuzzi, Michael J. Mumma, Belgian Science Policy Office, European Space Agency, Ministerio de Ciencia, Innovación y Universidades (España), European Commission, Fonds de la Recherche Scientifique (Fédération Wallonie-Bruxelles), UK Space Agency, National Aeronautics and Space Administration (US), Ministerio de Economía y Competitividad (España), and Agenzia Spaziale Italiana

Subjects
Atmosphere, Mars, Astronomy and Astrophysics, Atmosphere of Mars, Mars Exploration Program, Occultation, Methane, Astrobiology, law.invention, Trace gas, Orbiter, chemistry.chemical_compound, Altitude, chemistry, Space and Planetary Science, law, Environmental science, Infrared spectroscopy
Abstract

Methane (CH4) on Mars has attracted a great deal of attention since it was first detected in January 2003. As methane is considered a potential marker for past/present biological or geological activity, any possible detection would require evidence with strong statistical significance. Ethane (C2H6) and ethylene (C2H4) are also relevant chemical species as their shorter lifetimes in the Martian atmosphere make them excellent tracers for recent and ongoing releases. If detected, a CH4/C2Hn ratio could aid in constraining the potential source of organic production. Here we present the results of an extensive search for hydrocarbons in the Martian atmosphere in 240,000 solar occultation measurements performed by the ExoMars Trace Gas Orbiter/NOMAD instrument from April 2018 to April 2019. The observations are global, covering all longitudes and latitudes from 85°N to 85°S, and sampled from 6 to 100 km altitude with a typical vertical resolution of 2 km. There were no statistically significant detections of organics and new stringent upper limits for global ethane and ethylene were set at 0.1 ppbv and 0.7 ppbv, respectively. No global background level of methane was observed, obtaining an upper limit of 0.06 ppbv, in agreement with early results from ExoMars (Korablev et al., 2019). Dedicated searches for localized plumes at more than 2000 locations provided no positive detections, implying that if methane were released in strong and rapid events, the process would have to be sporadic. © 2020 Elsevier Inc. All rights reserved., The NOMAD experiment is led by the Royal Belgian Institute for Space Aeronomy (IASB-BIRA), assisted by Co-PI teams from Spain (IAACSIC), Italy (INAF-IAPS), and the United Kingdom (Open University). This project acknowledges funding by the Belgian Science Policy Office (BELSPO), with the financial and contractual coordination by the ESA Prodex Office (PEA 4000103401, 4000121493), by Spanish Ministry of Science and Innovation (MCIU) and by European funds under grants PGC2018-101836-B-I00 and ESP2017-87143-R (MINECO/FEDER), as well as by UK Space Agency through grants ST/V002295/1, ST/V005332/1 and ST/S00145X/1 and Italian Space Agency through grant 2018-2-HH.0. This work was supported by the Belgian Fonds de la Recherche Scientifique -FNRS under grant number 30442502 (ET_HOME). The IAA/CSIC team acknowledges financial support from the State Agency for Research of the Spanish MCIU through the 'Center of Excellence Severo Ochoa' award for the Instituto de Astrofisica de Andalucia (SEV-2017-0709). Canadian investigators were supported by the Canadian Space Agency. This work was supported by NASA's Mars Program Office under WBS 604796, "Participation in the TGO/NOMAD Investigation of Trace Gases on Mars". MC is supported by the NASA Postdoctoral Program at the NASA Goddard Space Flight Center, administered by Universities Space Research Association (USRA) under contract with NASA. S. A. is "Charge de Recherches" at the F.R.S.-FNRS. We would also like to thank Dr. Sara Faggi for valuable advice, expertise and continuous support during this study.

Published
2021

35. Water heavily fractionated as it ascends on Mars as revealed by ExoMars/NOMAD

Author

Shohei Aoki, Jose-Juan Lopez-Moreno, Manish R. Patel, Michael D. Smith, Ann Carine Vandaele, Giuliano Liuzzi, Ian Thomas, Elise W. Knutsen, Frank Daerden, Bojan Ristic, Nomad Team, Matteo Crismani, Lori Neary, Sébastien Viscardy, Geronimo L. Villanueva, James Holmes, Miguel Lopez-Valverde, Giancarlo Bellucci, Michael J. Mumma, Belgian Science Policy Office, European Space Agency, European Commission, UK Space Agency, Agenzia Spaziale Italiana, Ministerio de Ciencia e Innovación (España), and Ministerio de Economía y Competitividad (España)

Subjects
Multidisciplinary, 010504 meteorology & atmospheric sciences, Water on Mars, animal diseases, Astronomy, SciAdv r-articles, Mars Exploration Program, Equinox, Atmospheric sciences, 01 natural sciences, Altitude, Planet, Dust storm, 0103 physical sciences, Environmental science, Polar cap, 010303 astronomy & astrophysics, Research Articles, Research Article, 0105 earth and related environmental sciences
Abstract

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license, which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited., Isotopic ratios and, in particular, the water D/H ratio are powerful tracers of the evolution and transport of water on Mars. From measurements performed with ExoMars/NOMAD, we observe marked and rapid variability of the D/H along altitude on Mars and across the whole planet. The observations (from April 2018 to April 2019) sample a broad range of events on Mars, including a global dust storm, the evolution of water released from the southern polar cap during southern summer, the equinox phases, and a short but intense regional dust storm. In three instances, we observe water at very high altitudes (>80 km), the prime region where water is photodissociated and starts its escape to space. Rayleigh distillation appears the be the driving force affecting the D/H in many cases, yet in some instances, the exchange of water reservoirs with distinctive D/H could be responsible. © 2021 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science., This project acknowledges funding by the Belgian Science Policy Office (BELSPO), with the financial and contractual coordination by the ESA Prodex Office (PEA 4000103401 and 4000121493), by the Spanish MICINN through its Plan Nacional, by European funds under grants PGC2018-101836-B-I00 and ESP2017-87143-R (MINECO/FEDER), and by the Spanish Science Ministry Centro de Excelencia Severo Ochoa Program under grant SEV-2017-0709, as well as by the U.K. Space Agency through grants ST/R005761/1, ST/P001262/1, ST/R001405/1, and ST/S00145X/1 and the Italian Space Agency through grant 2018-2-HH.0. This work was supported by NASA’s Mars Program Office under WBS 604796, “Participation in the TGO/NOMAD investigation of trace gases on Mars” and by NASA’s SEEC initiative under grant number NNX17AH81A, “Remote sensing of planetary atmospheres in the solar system and beyond.” M.J.C. was supported by the NASA Postdoctoral Program at the NASA Goddard Space Flight Center, administered by Universities Space Research Association (USRA) under contract with NASA. S.A. is postdoctoral researcher of the Belgian Fund for Scientific Research (FNRS).

Published
2021

36. Psoas abscess by Candida spp. in an immunocompetent patient

Author

María Valero Soriano, Francisco Miguel González Valverde, and Antonio Albarracín Marín-Blázquez

Subjects
business.industry, Candida spp, Humans, Psoas Abscess, Medicine, business, Abscess, medicine.disease, Candida, Microbiology
Published
2021

38. Cross-talk between the calcium channel TRPV4 and reactive oxygen species interlocks adhesive and degradative functions of invadosomes

Author

Olivier Destaing, Christiane Oddou, Hans-Joachim Knölker, Yohann Couté, Edwige Hiriart-Bryant, Miguel A. Valverde, Corinne Albiges-Rizo, Paul Rivier, Cyril Boyault, René Martin, Sanela Vellino, Alexandra Kraut, Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (IAB), and Etablissement français du sang - Auvergne-Rhône-Alpes (EFS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Universitaire [Grenoble] (CHU)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)

Subjects
TRPV4, Podosome, [SDV]Life Sciences [q-bio], Integrin, TRPV Cation Channels, Dithionitrobenzoic Acid, Biology, MAP Kinase Kinase Kinase 5, Models, Biological, Mice, Myosin Type I, 03 medical and health sciences, 0302 clinical medicine, Cell Adhesion, invadosome, Animals, Humans, ASK1, Cysteine, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Reactive oxygen species, Voltage-dependent calcium channel, Effector, ECM degradation, Integrin beta1, Calcium channel, ROS, Hydrogen Peroxide, Cell Biology, Actins, Extracellular Matrix, 3. Good health, Cell biology, Protein Transport, HEK293 Cells, RAW 264.7 Cells, chemistry, Podosomes, biology.protein, Calcium, Reactive Oxygen Species, Genètica, 030217 neurology & neurosurgery
Abstract

Invadosomes support cell invasion by coupling both acto-adhesive and extracellular matrix degradative functions, which are apparently antagonistic. β1-integrin dynamics regulate this coupling, but the actual sensing mechanism and effectors involved have not yet been elucidated. Using genetic and reverse genetic approaches combined with biochemical and imaging techniques, we now show that the calcium channel TRPV4 colocalizes with β1-integrins at the invadosome periphery and regulates its activation and the coupling of acto-adhesive and degradative functions. TRPV4-mediated regulation of podosome function depends on its ability to sense reactive oxygen species (ROS) in invadosomes' microenvironment and involves activation of the ROS/calcium-sensitive kinase Ask1 and binding of the motor MYO1C. Furthermore, disease-associated TRPV4 gain-of-function mutations that modulate ECM degradation are also implicated in the ROS response, which provides new perspectives in our understanding of the pathophysiology of TRPV4 channelopathies. This work was funded by the Agence Nationale de la Recherche (ANR; invadocontrol; ANR-13-JSV2-0003-01) program and Ligue Contre le Cancer as “Equipe labellisée Ligue 2014” (EL2014.LNCC/CAR), the Spanish Ministry of Economy, Industry, and Competitiveness through grant RTI2018-099718, the institutional “Maria de Maeztu” Program for Units of Excellence in Research and Development, and FEDER funds. S. Vellino was funded by the European Marie-Sklodowska-Curie funding program. Proteomic experiments were partly supported by the Proteomics French Infrastructure (grant ANR-10-INBS-08-01) and Labex GRAL (grant ANR-10-LABX-49-01)

Published
2021

39. The fluid shear stress sensor TRPM7 regulates tumor cell intravasation

Author

Selma A. Serra, Christopher L. Yankaskas, Konstantinos Konstantopoulos, Julia Carrillo-Garcia, John D. Lewis, Konstantin Stoletov, Kaustav Bera, Soontorn Tuntithavornwat, Miguel A. Valverde, and Panagiotis Mistriotis

Subjects
0301 basic medicine, Multidisciplinary, RHOA, biology, Chemistry, Intravasation, SciAdv r-articles, Life Sciences, CDC42, macromolecular substances, Cell Biology, Shear (sheet metal), 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, TRPM7, 030220 oncology & carcinogenesis, Biophysics, Shear stress, biology.protein, Signal transduction, Intravital microscopy, Research Articles, Research Article
Abstract

Fluid shear sensing via TRPM7 limits tumor cell intravasation by activating RhoA/myosin and calmodulin/IQGAP1/Cdc42 pathways., Tumor cell intravasation preferentially occurs in regions of low fluid shear because high shear is detrimental to tumor cells. Here, we describe a molecular mechanism by which cells avoid high shear during intravasation. The transition from migration to intravasation was modeled using a microfluidic device where cells migrating inside longitudinal tissue-like microchannels encounter an orthogonal channel in which fluid flow induces physiological shear stresses. This approach was complemented with intravital microscopy, patch-clamp, and signal transduction imaging techniques. Fluid shear–induced activation of the transient receptor potential melastatin 7 (TRPM7) channel promotes extracellular calcium influx, which then activates RhoA/myosin-II and calmodulin/IQGAP1/Cdc42 pathways to coordinate reversal of migration direction, thereby avoiding shear stress. Cells displaying higher shear sensitivity due to higher TRPM7 activity levels intravasate less efficiently and establish less invasive metastatic lesions. This study provides a mechanistic interpretation for the role of shear stress and its sensor, TRPM7, in tumor cell intravasation.

Published
2021

40. Psychological inflexibility and mental health symptoms during the COVID-19 lockdown in Spain: A longitudinal study

Author

Antonio Cepeda-Benito, Miguel Rodríguez-Valverde, Mónica Hernández-López, and Pilar Díaz-Pavón

Subjects
medicine.medical_specialty, Longitudinal study, 2019-20 coronavirus outbreak, Organizational Behavior and Human Resource Management, Health (social science), Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), COVID-19, Mental health, Health(social science), Behavioral Neuroscience, Lockdown, medicine, Original Article, Psychological inflexibility, Psychological flexibility, Psychiatry, Psychology, Applied Psychology, Ecology, Evolution, Behavior and Systematics
Abstract

Spain, one of the European countries most affected by the COVID-19 pandemic, underwent a strict lockdown between March and May 2020. This study examines longitudinally the evolution of both psychological inflexibility and mental health symptoms in a sample of college students from the beginning and throughout the end of the mandated lockdown period. We present the results from 197 participants who responded to an online survey at least at two of three data-collection waves scheduled at the beginning (N = 226), halfway (N = 172), and end (N = 188) of the lockdown. The analyses revealed that psychological inflexibility and symptomatology increased over time, and that inflexibility at the beginning of the lockdown indirectly predicted self-reported symptoms at the end of the lockdown via autoregressive parallel paths that also connected cross-sectionally to reveal that changes in inflexibility were predictive of changes in mental health. These results present a dynamic and robust relationship between psychological inflexibility and mental health symptoms throughout a relatively long and presumably stressful period of time.

Published
2021
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41. Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study

Author

Dmitri, Nepogodiev, Joana Ff Simoes, Elizabeth, Li, Maria, Picciochi, James, C Glasbey, Glauco, Baiocchi, Ruth, Blanco-Colino, Daoud, Chaudhry, Ehab, Alameer, Kariem, El-Boghdadly, Funmilola, Wuraola, Dhruva, Ghosh, Rohan, R Gujjuri, Ewen, M Harrison, Herman, Lule, Haytham, Kaafarani, Mohammad, Khosravi, Irmgard, Kronberger, Sezai, Leventoğlu, Harvinder, Mann, Kenneth, A Mclean, Mengistu Gebreyohanes Mengesha, Maria Marta Modolo, Faustin, Ntirenganya, Lisa, Norman, Oumaima, Outani, Riinu, Pius, Peter, Pockney, Ahmad Uzair Qureshi, April Camilla Roslani, Sohei, Satoi, Catherine, Shaw, Aneel, Bhangu, Omar, M Omar, Waheed-Ul-Rahman, Ahmed, Leah, Argus, Alasdair, Ball, Edward, P Bywater, Amanpreet, Brar, Brett, E Dawson, Irani, Duran, Muhammed, Elhadi, Conor, S Jones, Sivesh, K Kamarajah, James, M Keatley, Samuel, Lawday, Ella, J Marson, Riinu, Ots, Irène, Santos, Elliott, H Taylor, Isobel, M Trout, Chris, Varghese, Mary, L Venn, William, Xu, Irida, Dajti, Arben, Gjata, Salah Eddine Oussama Kacimi, Luis, Boccalatte, Daniel, Cox, Philip, Townend, Felix, Aigner, Irmgard Elisabeth Kronberger, Elgun, Samadov, Amer, Alderazi, Kamral, Hossain, Greg, Padmore, Gabrielle van Ramshorst, Ismaïl, Lawani, Anis, Cerovac, Samir, Delibegovic, Gustavo Mendonça Ataíde Gomes, Igor Lima Buarque, Muhammad, Gohar, Mihail, Slavchev, Chukwuemeka, Nwegbu, Arnav, Agarwal, Janet, Martin, Joshua, Ng-Kamstra, Maricarmen, Olivos, Wenhui, Lou, Dong-Lin, Ren, Jose Andres Calvache, Carlos, J Perez Rivera, Ana Danic Hadzibegovic, Tomislav, Kopjar, Jakov, Mihanovic, Pablo Mijahil Avilés Jiménez, Nikolaos, Gouvas, Jaroslav, Klat, René, Novysedlák, Nicolas, Amisi, Peter, Christensen, Alaa, El-Hussuna, Sylvia, Batista, Eddy, Lincango-Naranjo, Sameh, Emile, Danilo Alfonso Arévalo Sandoval, Hailu, Dhufera, Samuel, Hailu, Mengistu, G Mengesha, Joonas, H Kauppila, Alexis, P Arnaud, Zaza, Demetrashvili, Markus, Albertsmeier, Hans, Lederhuber, Markus, W Löffler, Daniel Kwesi Acquah, Bernard, Ofori, Stephen, Tabiri, Symeon, Metallidis, Georgios, Tsoulfas, Maria-Lorena, Aguilera-Arevalo, Gustavo, Recinos, Tamás, Mersich, Dániel, Wettstein, Gabriele, Kembuan, Peiman Brouki Milan, Mohammad Hossein Khosravi, Masoud, Mozafari, Ahmed, Hilmi, Helen, Mohan, Oded, Zmora, Gaetano, Gallo, Francesco, Pata, Gianluca, Pellino, Yuki, Fujimoto, Naoto, Kuroda, Mohamad, K Abou Chaar, Faris, Ayasra, Ildar, Fakhradiyev, Intisar Hisham Said Hamdun, Jang, Jin-Young, Mohammad, Jamal, Lina, Karout, Aiste, Gulla, Fanjandrainy, Rasoaherinomenjanahary, Luc Hervé Samison, Iran Irani Durán Sánchez, Diana Samantha Gonzalez, Laura, Martinez, María José Martínez, Alejandra, Nayen, Antonio Ramos-De la Medina, Jade, Nunez, Pueya Rashid Nashidengo, Rakesh, Shah, Ashish Lal Shrestha, Pascal, Jonker, Schelto, Kruijff, Milou, Noltes, Pieter, Steinkamp, Deborah, Wright, Lukman, Abdur-Rahman, Adesoji, Ademuyiwa, Adewale, Adisa, Babatunde, Osinaike, Justina, Seyi-Olajide, Omolara, Williams, Emmanuel, Williams, Sofija, Pejkova, Zainab Al Balushi, Raza, Sayyed, Mustafa Abo Mohsen, Sadi, A Abukhalaf, Moises, Cukier, Hugo, Gomez-Fernandez, Sebastian Shu Yip, Ximena Paola Vasquez Ojeda, Marie Dione Sacdalan, Piotr, Major, José, Azevedo, Miguel, F Cunha, Ahmad, Zarour, Eduard-Alexandru, Bonci, Ionut, Negoi, Sergey, Efetov, Viktor, Kochetkov, Andrey, Litvin, Jc Allen Ingabire, Georges, Bucyibaruta, Ntirenganya, Faustin, Sosthene, Habumuremyi, Alphonsine, Imanishimwe, Haragirimana Jean de Dieu, Emmanuel, Munyaneza, Isaie, Ncogoza, Abdourahmane, Ndong, Dejan, Radenkovic, Min Hoe Chew, Frederick, Koh, James, Ngu, Arpád, Panyko, Uros, Bele, Jurij Aleš Košir, Hassan, Daoud, Ana Maria Minaya Bravo, Umesh, Jayarajah, Dakshitha, Wickramasinghe, Mohammed Elmujtba Adam Essa Adam, Martin, Rutegård, Malin, Sund, Michel, Adamina, Eleftherios, Gialamas, Karoline, Horisberger, Muhammad, Alshaar, Abel, Huang, Varut, Lohsiriwat, Shane, Charles, Haithem, Jlassi, Arda, Isik, Hervé Monka Lekuya, Slava, Kopetskyi, Hayder, Alsaadi, Sattar, Alshryda, Osaid, Alser, Brittany, Bankhead-Kendall, Kerry, Breen, Hassan, Mashbari, Fernando Bonilla Cal, Hamza, Al-Naggar, Mayaba, Maimbo, Dennis, Mazingi, Tom, Abbott, Melika, Akhbari, Ruth, Benson, Shivam, Bhanderi, Bruce, Biccard, Edward, Caruana, Sohini, Chakrabortee, Reema, Chapatwala, Ainhoa, Costas-Chavarri, Andreas, K Demetriades, Anant, Desai, Salomone Di Saverio, Thomas, Drake, John, Edwards, Jonathan, Evans, Marco, Fiore, Samuel, Ford, Christina, Fotopoulou, Alexander, Fowler, Kaori, Futaba, Ian, Ganly, Harelimana Grace James, Ewen, Griffiths, Alessandro, Gronchi, Peter, Hutchinson, Gabriella Yael Hyman, Joseph, Incorvia, Ritu, Jain, Michael, Jenkinson, Tabassum, Khan, Stephen Richard Knight, Angelos, Kolias, Søren, Kudsk-Iversen, Tsun Yu Kwan, Elaine, Leung, Julio, Mayol, Siobhan, Mckay, John, G Meara, Emily, Mills, Susan, Moug, Akshay, Patel, Roberto, Perinotti, Henry, E Rice, Keith, Roberts, Andrew, Schache, Richard, Shaw, Neil, Smart, Matthew, Stephens, Grant, D Stewart, Ella, Teasdale, Peter, Vaughan-Shaw, Raghavan, Vidya, Naomi, Wright, Natalie, Zimmelman, Ervis, Agastra, Dariel, Thereska, Sergio Martin Lucchini, Veronica, Laudani, Carina, Chwat, Ivana Ines Pedraza Salazar, Diana Alejandra Pantoja Pachajoa, Agustin, Duro, José Alfredo Calderón Arancibia, Giuliana, D'Aulerio, Nagendra, Dudi-Venkata, Natasha, Egoroff, Shebani, Farik, Natalie, Lott, Jana-Lee, Moss, Sarah, Rennie, Lorwai, Tan, Uyen Giao Vo, David, Watson, David, Watters, Tim, Bright, Paul, Hollington, Xuanyu, Zhou, Hidde, M Kroon, Anthony, Farfus, John, Barker, Eleanor, Watson, Sean, Stevens, Haider, Latif, Amanda Caroline Dawson, Alwin, Chuan, Vijayaragavan, Muralidharan, Enoch, Wong, Travis, Ackermann, Maurizio, Pacilli, Russell, Hodgson, Alexander, Heriot, Peter, Choong, Wendy, Brown, Surjit, Lidder, Justin, Yeung, Luke, Traeger, Guillermo, Regalo, Ralph, Gourlay, Sarit, Badiani, Cherry, Koh, Soni, Putnis, Fayza, Haider, Ashrarur Rahman Mitul, Niels, Komen, Bert, Dhondt, Serge, Cappeliez, Manon, Pigeolet, Martijn, Schoneveld, Jasper, Stijns, Wouter, Oosterlinck, Nicolas, Flamey, Cyrille, Kpangon, Mouhamed, Agbadebo, Sèmèvo Romaric Tobome, Aldo Vieira Barros, Samuel Aguiar Júnior, Heloisa Galvão do Amaral Campos, Jefferson, Gross, Felipe José Fernandez Coimbra, Luiz Paulo Kowalski, Fabiana, Makdissi, Suely, Nakagawa, Joao Pedreira Duprat Neto, Jose Guilherme Vartanian, Guilherme, Yazbek, Stenio, C Zequi, Ronald, Flumignan, Natalia, Jaworska, Angela, Dell, Harsha, Shanthanna, Abdollah, Behzadi, Carolyn, Nessim, Michelle, Mozel, Pascal, St-Germain, Crispin, Russell, Gary, Groot, Najib, Safieddine, Duminda, Wijeysundera, Antoine, Eskander, Sami, Chadi, Shawn, Mackenzie, Alana, Flexman, Fernando, Heredia, Julio, Villanueva, Sofia, Waissbluth, Roberto, Macchiavello, Mario, I Escudero, Tyare, Fuentes, Ximena, Mimica, Dinimo Bolivar Saenz, Lina, Caicedo, Juan Pablo Alzate, Joaquin, Luna, Nestor Fabian Pedraza Alonso, Camilo Ortiz Silva, Juliana, Rodriguez, Liliana, Silva-Igua, Martha Luz Torres, Lina María Trujillo, Albaro José Nieto Calvache, Julián, Balanta-Melo, Rafael, Figueroa-Casanova, Oscar-Julián, García-Montoya, Carlos Andres Marulanda Toro, Marcela Velez Botero, Maria Clara Mendoza Arango, Eneida Diaz Martinez, Valentina Gutiérrez Perdomo, Emileth, Montenegro, Julia, Rodriguez-Abreu, Dolores, Mejía, Galal, Abouelnagah, Sameh, Shehata, Ahmed Hossam Eldin Fouad Rida, Ramy, A Hassan, Mahmoud, M Saad, Mohamed Reda Loaloa, Badr, Mostafa, Mohamed, Qassem, Mohamed, Fahmy, Hesham, Abozied, Ahmed, Y Azzam, Sherief, Ghozy, Asser, Sallam, Ahmed, Shehta, Mohamed, Abdelkhalek, Rehab, Samaka, Amr, Morsy, Ahmed Elshawadfy Sherif, Abraham, Negussie, Tigist, Fisseha, Kibruyisfaw, Shumbash, Metasebia, Abebe, Seid Mohammed Yasin, Yemisirach Bizuneh Akililu, Abebe, Megersa, Teshome, Tefera, Melatework, Assefa, Bahru, Atnafu, Bereket, Tsegaye, Yoseph Solomon Bezabih, Silamlak, Sisay, Kebebe, Bekele, Moa, Jira, Habtamu, Derilo, Eyueal, Degefa, Anteneh, Tadesse, Melkamu, Nidaw, Elise, Sarjanoja, Sylvie, Testelin, Sophie, Boucher, Lionel, Jouffret, Zaher, Lakkis, Alban Zarzavadjian Le Bian, Luke, Harper, Marc Danguy des Déserts, Benoît, André, Karem, Slim, Romain, Verhaeghe, Andrea, Police, Edouard, Girard, Alexandre, Chebaro, Armande Subayi Nkembi, Laurent, Arnalsteen, Quentin, Ballouhey, Diane, Mege, Clement, Jeandel, Emilie, Duchalais, Pierre-Alban, Bouche, Gilles, Manceau, Célia, Crétolle, Erik, Hervieux, Noémie, Girard, Agathe, Seguin-Givelet, Sebastien, Gaujoux, Belinda De Simone, Matthieu, Boisson, Damien, Bergeat, Fabien, Fredon, Francesco, Nappi, Radwan, Kassir, Aurélien, Scalabre, Federico, Migliorelli, Anne-Cecile, Ezanno, Barbara, Seeliger, Charlotte, Vaysse, Helene, Charbonneau, Vincent, Misrai, Olivier, Abbo, Martina Aida Angeles, Laurent, Brunaud, Ali, Modabber, Sebastian, Wolf, Carsten, Kamphues, Philipp, Höhn, Tim, R Glowka, Alexander Christopher Rokohl, Ulrich, Bork, Georg, Fluegen, Raymund, E Horch, Andrea, Schmedding, Andreas, Schnitzbauer, Helge, Eberbach, Daniel, Schlager, Fritz, Spelsberg, Lena, Keppler, Andreas, Hecker, Susanne, Wolfer, Ulrich, Ronellenfitsch, Christine, Nitschke, Christian, Peiper, Ibrahim, Hakami, Stefan, Welter, Karine, Nikolaieva, Andreas, Roth, Judith, Lindert, Konstantinos, Gousias, Anke, Rissmann, Valerie Catherine Linz, Nuh, Rahbari, Marie-Claire, Rassweiler-Seyfried, Anna Eleonora Gut, Jens, Gempt, Daniel, Reim, Arthur, Wagner, Alexander, M Keppler, Mircea Gabriel Stoleriu, Tim, Saier, Josef, Stadler, Julia Christina Kaiser, Stefan, M Brunner, Karin, Pfister, Jonas, Herzberg, Kai, Nowak, Tobias, Reinhard, Gregor, A Stavrou, Alfred, Königsrainer, Christian, Konrads, Markus, Quante, Simon, Laban, Silke von Pusch, Markus, Hirschburger, Johannes, Doerner, Armin, Wiegering, Ekaterini Christina Tampaki, Alitza Gutiérrez Ruiz, Alejandra, Rodas, Ana Lucía Portilla, Jacqueline, Carrera, Amalia Barrios Duarte, Megan, Lowey, Sabrina, Barillas, Atul, Suroy, Dhaivat, Vaishnav, Raghunandan Gorantlu Chowdappa, Irappa, Madabhavi, Dhananjaya, Bhat, Sunil Kumar Venkatappa, Sumit, Thakar, Kavitha, Jain, Aruna, Kumar, Manoj, Nagar, Tushar, Mishra, Arunkumar, Sekar, Anand, Gupta, Lileswar, Kaman, Madhivanan, Karthigeyan, Manjul, Tripathi, Ashwin, Rammohan, Sudheer Othiyil Vayoth, Anupama, Rajanbabu, Anbukkani, Subbian, Rahul, Gupta, Monish, Raut, Nissi, Evelyn, R Lavanya Kannaiyan, Anil, Matai, Sanjeev, Misra, Vishal, Bhende, Sathish, Muthu, Indranil, Ghosh, Abhishek, Sharma, Ankur, Bajaj, Shiv, Rajan, Gaurav, Agarwal, Pranay, Pawar, Philip, Alexander, M Vijayakumar Vijayakumar, Zeeshan, Hameed, Badareesh, L, Navneet Kumar Chaudhry, Lipika, Baliarsing, Satish, Dharap, Amruta, Kulkarni, Yuvaraja, Thyavihally, Rahul Deo Sharma, S Pramesh, C, Rajesh, Soni, Surya Kumar Dube, Shilpa, Sharma, Harvinder, Singh, Lovenish, Bains, Rahul, Ghodke, Ashwani, Kumar, Vivek, Sodhai, Suvendu, Maji, Somprakas, Basu, Chandrashekhar, Mahakalkar, Ravi, Kannan, Asif, Mehraj, Ranganath, N, Ashish, Phadnis, Yadev, I, Alfie, Kavalakat, Rohin, Mittal, Karthik Chandra Vallam, Hamed, Akhavizadegan, Esmaeil Rezghi Maleki, Naser Yousefzadeh Kandevani, Hilary, Ikele, Catherine, Mcnestry, Christina, Fleming, Stephen, O'Brien, Sami Abd Elwahab, Niall, Davis, Mohsen, Javadpour, Brendan, Mcdonnell, Clare, O Connor, Jarlath, Bolger, Cillian, Clancy, Stefanie, M Croghan, Noel, Donlon, Carolyn, Cullinane, Ben, Creavin, Muheilan, Muheilan, Helen, Earley, Syed Mohammad Umar Kabir, Muhammad, Fahadullah, Éanna, Ryan, Tara, Connelly, Daisuke, Hashimoto, Majdi Ali Alqudah, Amer, Alajalen, Rand, Y Omari, Abdulrahman, Qasem, Yazan, Alawneh, Amer, Ahmad, Omar, Aladawi, Bourhan, Alrayes, Hanan, Haidar, Shatha, Husain, Faisal, Qassem, Adnan, Sumadi, Ala'a Abu Salhiyeh, Balqees Mahmoud Al-Manaseer, Zaid, Alsunna, Hazim, Ra'Ed, Faten Reyad Bani Hamad, Amro, Abuleil, Elmi Ahmed Mohamed Jimaale, Marah, Abu-Mehsen, Noor, Olaywah, Omar, Wafi, Hazim, Ababneh, Luai, Abu-Ismail, Almu'Atasim, Khamees, Ahmad, Alkhatib, Raikhan, Bolatbekova, Mukhtar, Kulimbet, Talgat, Nurgozhin, Timur, Saliev, Baurzhan, Zhussupov, Ydyrys, Almabayev, Dilyara, Kaidarova, Khalil, Tamoos, Ahmed, Aqeelah, Alsnosy Abdullah Khalefa Mohammed, Faraj Al Maadany, Ghadah, Alkadeeki, Milad, Gahwagi, Wafa, Aldressi, Mohamed, Amnaina, Arowa Hassan Abdulrahman Alansari, Akram, Alkaseek, Ghozlan, Yagoub, Anass Ben Amer, Marwa, Salem, Ayman, Almugaddami, Dania, Burgan, Mohammed, Abdelkabir, Khayriyah, Alshareef, Rayet Al Islam Ben Jouira, Ayman, Meelad, Ahmad, Bouhuwaish, Sumayya Essayah Dwaga, Houda, Khalifa, Bushray, Almiqlash, Taha, Suliaman, Mohammed, Alawami, Fras, Elhajdawe, Hajir, Aboazamazem, Ibrahim, Ellojli, Ahmed, Msherghi, Ismail Ali Saleh, Mohammed, Alayan, Marcel Didier Ndayishyigikiye, Akutu, Munyika, Philipp, Plarre, David, W Borowski, Cameron, Wells, Rebecca, Teague, Brodie, Elliott, David, Kieser, Omar, Mohyieldin, Nick, Mcintosh, Cheyaanthan, Haran, Jasmin, King, Jeong, Ha, Matthew James McGuinness, Opeoluwa, Adesanya, Julius, Olaogun, Akinola, Akinmade, Kefas, Bwala, Peter, Agbonrofo, Akinwale, Afolabi, Usang, Usang, Sebastian, Ekenze, Samson, Olori, Taiwo Akeem Lawal, Abiodun, Okunlola, Stephen, Kache, Danjuma, Sale, Lofty-John, Anyanwu, Chukwuma, Okereke, Musliu Adetola Tolani, Venko, Filipce, Lazar, Todorovic, Sotir, Stavridis, John George Massoud, Sareyah, Alsibai, Rizwan, Sultan, Humera Naz Altaf, Abu Bakar Hafeez Bhatti, Shahzad Hussain Waqar, Aliya, Aziz, Asad Ali Kerawala, Lajpat, Rai, Mariyah, Anwer, Aiman, Tariq, Bushra, Ayub, Sami Ullah Niazi, Muhammad Yasir Naseem, Muhammad Zeeshan Sarwar, Muhammad Imran Khokhar, Imdad Ahmad Zahid, Haroon Javaid Majid, Nabila, Talat, Muhammad, Asif, Muhammad Hamid Chaudhary, Umer, Farooq, Siddique, Ahmad, Waleed, Mabood, Syed Imran Bukhari, Muhammad, Tariq, Eesha, Yaqoob, Saad, Javed, Muhammad Usman Malik, Hassan Nawaz Yaqoob, Glenda Marina Falcon Pacheco, Robinson Mas Melendez, Arazzelly Del Pilar Paucar Urbina, Jose Rios Chiuyari, Carlos Eduardo Otiniano Alvarado, Lorena Fuentes Rivera Lau, Giuliano, Borda-Luque, Milagros, Niquen-Jimenez, Claudia, Arias, Sergio, Zegarra, Jenner Betalleluz Pallardel, Regina Amparo Ugarte Oscco, Gian, Mendiola, Yahaira Tatiana Carpio Colmenares, Carlos Shiraishi Zapata, Maria Rosa Ortiz, Filipe Castro Borges, Octavio, Viveiros, Pedro, Serralheiro, Paulo, Santos-Costa, Filipa, Mendes, Miguel Rocha Melo, Paulo, Cardoso, Ana, Soares, Rita Gonçalves Pereira, Nelson, Silva, André, Caiado, Maria Luís Sacras, Pedro, Azevedo, Rui, Almeida-Reis, João, Oliveira, Jorge, Nogueiro, Mafalda, Sampaio-Alves, Luciana Cidade Costa, Catarina, Baía, Ana Cláudia Deus, Rita, Branquinho, André, Marçal, André, Tojal, Silviu Tiberiu Makkai-Popa, Aurel, Mironescu, Florin, Grama, Elena Adelina Toma, Daniela, Filipescu, Nicolae, Bacalbasa, Natalia, Motas, Sebastian, Ionescu, Octav, Ginghina, Radu, Costea, Narcis Octavian Zarnescu, Radu, Drasovean, Mihail-Gabriel, Dimofte, Vlad, Porumb, Mikhail, Kirov, Yegor, Molitvin, Vadim, Pykhteev, Marianna, Raevskaya, Aleksandr, Butyrskii, Mushabab, Alshahrani, Azah, Althumairi, Nasser, Alzerwi, Ahmed Al Ameer, Tariq, Madkhali, Abddulrahman Saleh Almulhim, Salman, Ghazwani, Abdu, Ayoub, Othman, Iskander, Mohammed, Ghunaim, Mohammed, Alharthi, Turki, M Alzaidi, Mohammad, Alyami, Abdulrahman Al Amri, Abdullah, Alfakhri, Amal, Alhefdhi, Sharfuddin, Chowdhury, Thamer, Nouh, Ameen, Alshehri, Abdulrahman, Alzahrani, Yousef, Alalawi, Selmy, Awad, Ibrahima, Konate, Jacques, Tendeng, Nan Zun Teo, Sabra, Aqil, Cristina Barrena López, Ana Sánchez Mozo, Antonio Rodriguez Infante, Patricia Caja Vivancos, Mikel, Prieto, Igor Alberdi San Roman, Laura Gomez Fernandez, Josep Maria Muñoz Vives, Anna, Carreras-Castañer, Berta, Díaz-Feijoo, Ramon, Sieira-Gil, Victor, Turrado-Rodriguez, Anna Sánchez López, Santiago, Sánchez-Cabús, Marta Jimenez Toscano, MªPilar Canals Sin, Saura García Laura, Oriol Martin Sole, Pedro Palazon Bellver, Sonia, Pérez-Bertólez, Jordi, Prat-Ortells, Mireia Riba Martínez, Josep, Rubio-Palau, Xavier, Tarrado, Jorge, Nuñez, Veronica Alonso Mendoza, Coro, Bescós, Eloy, Espin-Basany, Martin, Espinosa-Bravo, Daniel, Gil-Sala, Susana, González-Suárez, Nuria Montferrer Estruch, Lucia Porteiro Mariño, Ana, Rodríguez-Tesouro, Fabian Rojas Portilla, M Pilar Tormos Pérez, Inmaculada, Vives, Unai Garcia De Cortazar, Kiara, Tudela, Aitor, Landaluce-Olavarria, Mercedes Estaire Gómez, Jorge, Almoguera, Bakarne, Ugarte-Sierra, Virginia, Jimenez, Marta, Bertrand, Laura Cárdenas Puiggrós, Olga, Delisau-Puig, Jorge, Garcia-Adamez, David Julià Bergkvist, Eloy, Maldonado-Marcos, Lucia Diego García, Marta Roldón Golet, Iván, Soto-Darias, Aida Cristina Rahy-Martín, Diego, Enjuto, Adolfo, Ramos-Luengo, Juan Delgado Fernandez, Carolina Lugo Duarte, Cristina Ojeda Thies, Lucila, Marquez, Diana Crego Vita, Jana, Dziakova, Jorge Caño Velasco, Olga, Mateo-Sierra, Begoña, Quintana-Villamandos, Cristina Rey Valcarcel, Javier, Rio, Laura Román García de León, Marcello Di Martino, Jorge, Prada, Javier Serrano González, Manuel, Losada, Jose Tomas Castell Gomez, Ramon, Corripio-Sanchez, Alexander, Forero-Torres, José Manuel Morales-Puebla, Hanna, Perez-Chrzanowska, Santiago Valderrabano Gonzalez, Alvaro, Yebes, Ignacio, Zapardiel, Manuel Diez Alonso, Nelson Morales Palacios, Alberto Cabañero Sánchez, Fátima Sánchez Fernández, Alfredo Abad Gurumeta, Ane, Abad-Motos, Fernando, Corella, Javier, Ripollés-Melchor, Rosa, Sanz-Gonzalez, Marta Alcaraz Fuentes, Maria Teresa Fernández Martín, Pablo Calvo Espino, Milagros Carrasco Prats, Antonio-José, Fernández-López, Damián García Escudero, Vanesa Garcia Soria, Jesús Aarón Martínez Alonso, Miguel, Ruiz-Marín, Beatriz Gómez Pérez, Joaquin, Moya-Angeler, Daniel Fernández Martínez, Heura Llaquet Bayo, Enrique, Colás-Ruiz, Susana Bella Romera, M Teresa Gavaldà Pellicé, Misericòrdia Jordà Solé, Enrique Jose Ruiz Velasquez, Bernardo, Núñez, Raul, Jimenez, Jon, Zabaleta, Maria Jose González-Gimeno, Irene Ortega Vázquez, Antonio Perez Ferrer, Rubén, Martín-Láez, Marcelo Moreno Suarez, Miguel Angel Freiria Eiras, Irene, Ramallo-Solís, Juan-Carlos, Gomez-Rosado, Jose Ramon Oliver Guillen, Mar Achalandabaso Boira, Juan Carlos Catalá Bauset, Julio, Domenech, Rafael, Badenes, Juan Carlos Bernal-Sprekelsen, Jorge, Sancho-Muriel, Beatriz De Andrés-Asenjo, Francisco, J Tejero-Pintor, Marc, Vallve-Bernal, Alba Vazquez Melero, Laura Sánchez Blasco, Jorge, Escartin, Victoria Duque Mallén, Selvaratnam, Srishankar, Charitha, Sooriyabandara, Oshan, Basnayake, Nalaka, Gunawansa, Prabuth Dulanjan Weeraddana, Thanusan, Vimalakanthan, Shanthamoorthy, Gishanthan, Pramodh, Chandrasinghe, Marc-Olivier, Sauvain, Ahmad, Ghazal, Yusra, Al-Sabbagh, Turki, Alhassoun, Sara Maa Albared, Antoine, Naem, Hareth, Alnahr, Ghassan, Jisry, Ali, Hammed, Okedi Francis Xaviour, Gaston, Turinawe, Isaac, Mubezi, Franck, K Sikakulya, Andrew, Kakeeto, Wilberforce, M Kabweru, Ronald, Kiweewa, Paul, Matovu, Otolia, Isaac, Mohamed, Mashhour, Amin El Helw, Safeena, Kherani, Awadelkarim, Mohamed, Ferial Mohamed Ali Abbas, Diary, Mohammed, Ehab, Aldlyami, Rakesh, Kundra, Antony Louis Rex Michael, Kareem, S Khalil, Rachel, Dbeis, Shafaque, Shaikh, Jenny, Ferry, Aiman, Jamal, Haleema, Siddique, Rishi, Das, Nikhil, Ponugoti, Pornjittra, Rattanasirivilai, Asma, Sultana, Frances, Mosley, Matthew, Chan, Antony, Bateman, Gareth, Davies-Jones, Fanourios, Georgiades, Navid, Ahmadi, Aman, Coonar, Mariam, Baig, Chetan, Khatri, Arthika, Surendran, Julian, Sonksen, Robert, Sinnerton, Caitlin, Brennan, Gemma, Faulkner, Michael, Greenhalgh, Hannah, Emerson, Kiran, Singisetti, Joshua, Totty, Michael, Wilson, Terence, Lo, Harriet, Corbett, Ijeoma, Okonkwo, Gill, Arbane, Cyrus, Kerawala, Chetan, Parmar, Michael, Bath, Funlayo, Odejinmi, Jayesh, Sagar, Rishi, Talwar, Samuel, Newman, John, Hammond, John, Moir, Natalie, Duric, Tamas, Szakmany, Ahmar Iftikhar Talib, Mina, Youssef, Christopher, Lewis-Lloyd, Mariam, Lami, Khurram, Ayub, Benjamin, Dean, Supriya, Balasubramanya, Sathya, Lakpriya, Luke, Rogers, Paul, Turner, Mark, Maher, Kohila, Sigamoney, Jihène El Kafsi, John, Hardie, David, Johnson, Christin, Henein, Marianne, Hollyman, Ketan, Agarwal, Simon, Powell, Govind Singh Chauhan, Rakesh, Patel, Joel, Gagnier, Heather, Carmichael, Aurora, Kristofor, A Olson, Eric, Etchill, Sameer, Hirji, Matthew, Naunheim, Frederick, Drake, Caroline, Reinke, Anna, Alecci, Dennis, Vaysburg, Jennifer, Rodriquez, Emily, Shih, Vin Shen Ban, Julia, Coleman, Krista, Kaups-Fresno, Emmanouil, Giorgakis, Maggie, Dinome, Neal, Bhutiani, Omar, Alnachoukati, Taylor, Aiken, Thomas, Diehl, Ankush, Gosain, Rishi, Rattan, Muhammad Owais Abdul Ghani, Nensi Melissa Ruzgar, Anna, Liveris, Nina, Glass, Charu, Paranjape, Theresa, Chin, Antonio, Meola, Kristina, Nicholson, John, Squiers, Stephanie, Lueckel, Janani, Reisenauer, Rachael, Callcut, Ahmed, Mansour, Allison, Berndtson, Lucy, Kornblith, Sara, Seegert, Paulo, Martins, 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Amanda Lira Dos Santos Leite, Laercio, Pol-Fachin, Tainá Santos Bezerra, Alcimar Lavareda Dos Santos Junior Alcimar, Robson, Amorim, Maria Eduarda Bellotti Leão, João José Corrêa Bergamasco, Cintia Cardoso Pinheiro, Rubem Alves Da Silva Neto, Elaine Francisca De Araújo, Lilian, Guimaraes, Tatiana, Liborio-Kimura, Isabelle Melo da Camara, Victor Ripardo Siqueira, Juan, Rodriguez, Jeancarllo, Silva, Rubem Alves Silva Junior, Cláudio, Cardoso, Andre, Guimaraes, Wislene Sarajane Moreira Alves, Agna Soares Da Silva Menezes, Marcelo, Araujo, Kattiucy, Brito, Josie Marcelle Lira Albuquerque, Jairo Alberto Dussan-Sarria, Andressa, Souza, Andre Ricardo Stüker, Tiago, Bresciani, Luciana Cadore Stefani, Leandro Totti Cavazzola, Tainá, Costa, Matheus, Dasqueve, Gustavo De Bacco Marangon, Otávio Ritter Silveira Martins, Josy, Rodrigues, Guilherme Roloff Cardoso, Brasil Silva Neto, Tilaê, Soares, Aline, Zanella, Lucas Torelly Filippi, Enilde Eloena Guerra, Ricardo Pedrini Cruz, Antonio Nocchi Kalil, Gustavo, Laporte, Moacyr, Salem, Murilo de Lima Brazan, Caio Antonio de Campos Prado, Elaine Christine Dantas Moises, Hilda Satie Suto, Alice Gadotti Yasuda, Ana Carolina Tagliatti Zani, Roberto Cardoso Cardoso Dos Santos, Geraldo, Duarte, Edwaldo Edner Joviliano, Carolina Lourenço Gomes Dos Santos, Silvana Maria Quintana, Edwin, Tamashiro, Fabiana Cardoso Pereira Valera, Marília Veccechi Bijos Zaccaro, Isis, Andreotti, Leonardo, Lima, Wilson Salgado Jr, Alonço da Cunha Viana Júnior, Lana, Moutinho, Cora Pichler de Oliveira, Isabela Trindade Martins, Isabela Vieira Toledo, Marco Antonio Correa Guimaraes-Filho, Rodrigo, Arrivabeno, Claudio Bovolenta Murta, Danniel Frade Said, Jose Pontes Junior, Felipe Guimarães Pugliesi, Paulo, Gregorio, Alessandro, Mariani, Fabio, Minamoto, Juliana Lourenço da Silva, Bruno, Muller, Caio, Zanon, Vladimir, C Carvalho, Ana Lucia Munhoz Lima, Priscila, R Oliveira, Jorge Dos Santos Silva, Mariana Faccini Teixeira, Marco, Kulcsar, Leandro, Matos, Kamilla Schmitz Nunes, Joel Abdala Junior, Emne, Abdallah, Genival Barbosa Carvalho, Igor Correia de Farias, Cassia da Silva, Fabio Fernando Eloi Pinto, Luciana, Facure, André, Godoy, Bruna, Kupper, Fernanda, Leite, Matheus de Melo Lôbo, Henrique, Mantoan, Narimã, Marques, Tomas, Marques, João Paulo Medici, Silvio Melo Torres, Katheryne Merlos Garcia, Rafael Ribeiro Meduna, Ana Carolina Scintini Herbst, Silvana Soares Dos Santos, Bruna Tirapelli Gonçalves, Marcelo, Antonini, Carolina, Brienze, José Francisco Farah, Rodrigo, Gonçalves, Vinicius, Machado, Luis Roberto Nadal, Danilo Nadal Rodrigues, Adrieli, Pansani, Maria Luiza Rocha, Marcelo, Simonsen, Daniela, Tsuchiya, Rafaela, Vasques, Jorge, Amorim, Ana Alyra Carvalho, Rebeca, Correia, Brena Costa Dos Santos, Henrique Jorge Guedes Neto, Luis, Nakano, Mariana, Pereda, Vladimir, Vasconcelos, Jamile Barakat Awada, Guilherme, Gava, Tiago Riuji Ijichi, Nam Jin Kim, Rafael, Nunes, Fabio, Pinto, Thiago Henrique Sigoli Pereira, Gustavo Jardim Volpe, Arthur, Gatti, Caroline, Nardi, Ramon, Oliva, Layze Braz de Oliveira, Herica Emilia Félix de Carvalho, Ivonizete Pires Ribeiro, Gabriel Renan Soares Rodrigues, Álvaro Francisco Lopes de Sousa, Michel, Chebel, Paulo Henrique de Sousa Fernandes, Marcelo Augusto Faria Freitas, Juliano Rodrigues da Cunha, Zeenia, Ather, Dobromir, Dimitrov, Emil, Filipov, Elitsa, Gyokova, Ivelina, Ilieva, Tsvetomir, Ivanov, Martin, Karamanliev, Vasil, Neykov, Boyko, Atanasov, Nikolay, Belev, Paolina, Kamenova, Kaloyan, Tonev, Tsanko, Yotsov, Evguenia, Hristova, Kolyo, Spassov, Tsanko, Tsankov, Dragomir, Dardanov, Petar, Gribnev, Manol, Sokolov, James, Brown, John, Tanyi, Heather, Hurdle, Anthony, Maclean, Michael, Sander, Salim Al Riyami, Krittika, Bali, David, Bigam, Khaled, Dajani, Mehran, Anvari, Rafik, Bolis, David, Choi, Susan, Ellis, Michael, Gupta, Wael, Hanna, Dennis, Hong, Cynthia, Horner, Lea, Luketic, Peter, Moisiuk, Yaron, Shargall, Hilda, Alfaro, Nawar, Alkhamesi, Laura, Allen, Muriel, Brackstone, Eunice, Chan, Davy, Cheng, Jason, Chui, Nelson, Gonzalez, Brent, Lanting, S Danielle MacNeil, Robert, Mayer, Jacob, Mcgee, Mahesh, Nagappa, Nicholas, Power, Agya, Prempeh, Mehdi, Qiabi, Hassan, Razvi, Emil, Schemitsch, Herman, Sehmbi, Ushma, Shah, Yamini, Subramani, Edward, Vasarhelyi, Kelly, Vogt, Homer, Yang, Ali Ghorbani Abdehgah, Saba, Balvardi, Liane, Feldman, Julio Flavio Fiore Jr, Melissa, Hanson, Brent, Hopkins, Pepa, Kaneva, Lawrence, Lee, Julia, Leonard, Jad, Abou-Khalil, Andre, Martel, James, Stevenson, Susan, Lee, Richard, Merchant, Samuel, Avoine, Laurence, Belanger, Mathieu, Belanger, Etienne, Belzile, Anne-Sophie, Blais, Sofia, Boucher-Kovalik, Cindy, Boulanger-Gobeil, Etienne, Cardinal, Pierre-Olivier, Champagne, Jonathan, Cloutier, Simon, Corriveau-Durand, Mathieu, Cote, Maxime, Cote, Mathilde, Côté, Valérie, Courval, Suzanne, Demers, Christine, Desbiens, Mehdi El Ouazzani, Karine, Girard, Ève-Marie, Girard, Karo, Gosselin, Helene, Khuong, Nathalie, 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Philemon, Leung, Andrew, Lindberg, Juan Mata Gutierrez, Kelly, Mayson, Adam, Meneghetti, Drew, Phillips, John, Street, Carolina Carvajal Calderón, Daniel Alejandro Donoso Pizarro, Esteban, Fernández, Ángela, Molero, Nastassja, Mutarello, Jorge Núñez Lucic, Katherine Ochoa Gaete, Catalina Ruiz Lopez, Rina, Sepúlveda, Camila, Ulloa, Mauricio, Barreda, Matias, Dallaserra, Matías Günther Wood, Mauricio Sandoval Tobar, Francisco, Garcia-Huidobro, Jimena, Dona, Carolina Soto Diez, Daniel, Igor, Javier, Mena, José Tomás Reyes, Catalina Arredondo Soto, Jose, Campos, Javier, Gonzalez, Barbara, Rivera, Jaime, Altamirano-Villarroel, David, Cohn, Luis Marin de Amesti, Pedro, Recabal, Camilo, Sandoval, Bruno Catoia Fonseca, Monica, Contador, Andres, Hodali, Camila, Pincheira, Andrea Ramos Mantilla, Claudio Salas Garrido, Janina, Torres, Marco, Valenzuela, Zehua, Chen, Jiankun, Hu, Jin, Tao, Kun, Yang, Yuexin, Zhang, Yuan, Chen, Wang, Cunchuan, Wah, Yang, Xueli, Bai, Tingbo, Liang, Tao, Ma, Ning, Pu, Hanlin, Yin, Camilo, Caicedo, Diego Felipe Tellez Beltran, Alejandro, Escobar, Carolina Perez Granados, Lisbeth Alexandra Urueña Pinzon, Carlos, Bonilla, Diana, Santana, Oscar, Serrano, Andrea, Garcia, Fernando Giron Luque, Nasly, G Patino-Jaramillo, Laura Giselle Contreras Baquero, Nestor Augusto Muñoz Botero, Jhoana Andrea Murillo Castellanos, Andrea Juliana Vega Calvera, Lina, M Acosta Buitrago, Maria Paz Bohórquez-Tarazona, Paulo Andrés Cabrera Rivera, J Felipe Casas, Valeria Cormane Alfaro, Julian, Corso, Bayron, Guerra, Albert Franz Guerrero-Becerra, Akram Kadamani Abiyomaa, Felix Ramon Montes, Manuel Santiago Mosquera Paz, Camilo Andrés Polanía Sandoval, Natalia, Quintana, Carlos Fernando Roman Ortega, Carlos, Santacruz, Manuela, Téllez, Camilo Alejandro Velandia Sánchez, Fernando, Arias-Amézquita, Luis Felipe Cabrera Vargas, Natalia Cortes Murgueitio, Elkin, Escorcia, Kemel Ahmed Ghotme Ghotme, Jorge Luis Gomez-Mayorga, Alvaro Felipe Guerrero Vergel, Gabriel, Herrera-Almario, Eduardo, Londono-Schimmer, Juan, A Mejia, Guillermo, Monsalve, Camilo, Rodriguez, Juan Nicolas Rodriguez Niño, Luis Martín Rodríguez Ortegón, Daniel, Sanabria, Andres, Alvarez, Arnulfo, Andrade, Javier, Ardila-Montealegre, David, Baquero, Edgar Mauricio Barrios Vidales, María Alejandra Caicedo Giraldo, María Camila Carvajal, Maria, Castillo, Maria Carolina Castillo Florez, María Angelica Cendales, Danny Conde Monroy, Henry, Cortes, Mario, Daniel, Jairo De la Peña, Elena Leonor Delgado-Nieto, Hernando, Espitia, Carlos Figueroa Avendaño, Edgar Oswaldo Hernandez Burgos, Andres, Isaza-Restrepo, German, Londono, Margarita Maria Maldonado, Andrea, Montenegro, Juan Carlos Navarro, Jorge, Navarro-Alean, Katherine Parra Abaunza, Eliana, Pulido, Erika, M Ramírez Amaya, Carlos Eduardo Rey Chaves, Natalia Andrea Rivera Rincón, William Mauricio Riveros Castillo, Lizeth Rodriguez Sanchez, Wilson, Rubiano, Maria, Russi, Juan Carlos Sabogal Olarte, Javier Mauricio Salgado Tovar, Maria Juliana Sanchez, David Mauricio Solano Varela, Paula Torres Gomez, Marcial, Trillos, Ana María Vargas Patiño, Felipe, Vargas-Barato, Juan Pablo Villate Leon, María Alejandra Wagner Useche, Jesus, Acosta, Adriana, Almeciga, Luis Becerra Mendez, Rafael Jose Beltran, Ana, Bonilla, Miguel, Buitrago, Marino, Cabrera, Pedro Hernando Calderon Quiroz, Diego, Camacho-Nieto, Carlos Andrés Carvajal Fierro, Sergio Cervera Bonilla, Sandra, Diaz, Helena, Facundo, Jorge, Forero, Mauricio Garcia Mora, Karena Victoria Garcia Tirado, German Fabian Godoy Perez, Felipe, Gonzalez, Oscar, Guevara, Jairo Alonso Hernandez, David Ricardo Herrera Mora, Juan David Lalinde, Carlos, Lehmann, Eduardo Leon Llanos, Byron Eduardo Lopez De Mesa Lopez, Ivan, Mariño, Monica, Medina, Raúl Eduardo Pinilla Morales, Angela, Puerto, Andrea, Quintero-Ortíz, Juliana Rendón Hernández, Elio Fabio Sánchez Cortés, Alvaro Eduardo Sánchez Hernández, Raul, Suarez, Oscar, Suescun, Marco, Vanegas, Rodolfo, Varela, Jorge Luis Velez Bernal, David, Viveros-Carreño, Daniela Camargo Gómez, Angelica, Fletcher, Abel, Merchan, Euler Javier Burbano Luna, Indira, Cujiño, Mauricio Velasquez Galvis, Lina Maria Vergara Galliadi, Orlando Abonia Gonzalez Abonia Gonzalez, Maria Fernanda Acuna Saravia, Roberto, Arroyave, Jose Maria Barreto Angulo, Francisco Javier Bonilla-Escobar, Uriel, Cardona, Ivan Castañeda Giacometto, José Luis Castillo, Diego Fernando Castillo-Cobaleda, Diego Jose Caycedo Garcia, Brenda Marcela Coll Tello, Juan Carlos Dueñas-Ramirez, Oscar Andres Escobar Vidarte, Luis, Figueroa, Herney, Garcia-Perdomo, Alden, Gomez, Laura, Gomez, Alejandro, Gomez, Ana María Grande-Gil, David, Guarin, Natalia, Guzman, Enrique Herrera Castañeda, Marisol, Hinaoui, Anuar Armando Idrobo Escobar, Christian Kammerer Kammerer, Sergio, Leon, Carlos Antonio Llanos Lucero, Angie, López, Alexander Maximiliano Martinez-Blanco, Antonio José Montoya Casella, Ricardo Andres Niño Corredor, Sebastian, Ordoñez, Diego Alfredo Palta Uribe, 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Alvarez, Cesar David Galindo Regino, Angela Maria Giraldo Velasquez, Carlos Enrique Melo Moreno, Jorman, H Tejada, Jesus Hernan Tovar, German Alirio Tovar, Edison Alexander Benavides Hernández, Claudia Milena Orozco-Chamorro, Gustavo Adolfo Angel, Christian Ali Buesaquillo, Victor David Olave Montaño, Andrés, Sánchez-Gómez, Daniela Patricia Escalante Ureche, Jairo Martinez Garrido, Eben-Ezer, Genda, Fabrice, Eboma, Kristina, Bitunjac, Karlo, Grulović, Marijana, Vučković, Goran, Šantak, Emanuel, Borovic, Ana Bosak Versic, Damir, Hasandić, Natasa Poldan Grabar, Suzana Srsen Medancic, Lucija, Brkic, Sara, Cokarić, Petra Pavic Palac, Zeljka, Samac, Josipa, Tomić, Marija, Vrdoljak, Ivan, Bacic, Bernarda, Bakmaz, Nikolina Bratošević Vučičić, Domagoj, Brzic, Samir, Canovic, Emilio, Dijan, Maja Grgec Dragicevic, Robert, Karlo, Suzana, Konjevoda, Petra, Kovačević, Ivan, Kovačić, Frane, Markulić, Luka, Matak, Domagoj, Morović, Gordan, Perišić, Andrea, Simic, Neven, Skitarelić, Matea, Veršić, 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Ioanna, Pozotou, Olga, Stavrinidou, Anneza, Yiallourou, Lukáš, Burda, Michal, Dosoudil, Lubomir, Martinek, Wladyslaw, B Gawel, Milan, Lerch, Matúš, Peteja, Jan, Žatecký, Toman, Daniel, Martin, Formánek, Veronika, Javurkova, Markéta, Kepičová, Nicole, Macečková, Petr, Matousek, Ondrej, Simetka, Petr, Vavra, Karol, Zelenik, Jan, Černý, Sami, Khan, Robert, Lischke, Martin, Přibyl, Temoore, Younus, Yenuksha, Amarasena, Karel, Klíma, Setareh, Pirmorad, Zuzana, Hotová, Aleš, Mladěnka, Nulvin, Bozo, Julie Lykke Harbjerg, Louise, Hviid, Helle, Ø Kristensen, Mira, Mekhael, Mette Fugleberg Nielsen, Laerke, Paulsen, Saija, Sinimäki, Louise Zinck Mogensen, Peter, Bonde, Anders Lyng Ebbehøj, Anne-Sophie, Fenger, Aleksander Fjeld Haugstvedt, Christine Hangaard Hansen, Maria Lovisa Jönsson, Lars, N Jorgensen, Peter-Martin, Krarup, Anne-Louise, Lihn, Christian, Meyhoff, Helena, Otte, Anas Ould Si Amar, Henrik, Palm, Nis, Schlesinger, Henry, Smith, Ida, Tryggedsson, Anne Reiss Axelsen, Jens Kristian Baelum, Mark Bremholm Ellebaek, Signe Bremholm Ellebaek, Anders, Hogh, Maria, Acosta, Yancy, Acosta, Pedro, Baez, Luis Alfredo Betances, Luis Rodolfo Bonilla, Daniel, Cabreja, Wilton Cabrera Cruz, María Mabel Collado Expósito, Aldo, Crespo, Octavio, Cruz-Pineda, Claudio Samuel D'óleo García, Pedro, Díaz, Remberto, Escoto, Jatnna, Figueroa, Luis, Garcia, U Garcia-Dubus Rodriguez, Humberto, Gomez, Adrian, Grullon, Fatherin, Guerrero, Lillian, Guzman, Thelma Rocío Jiménez Mosquea, Engels, Lazala, Ariela, Lopez, Leeany Maletta Francisco, Jhomayri, Mercado, Herisardy, Munoz, Jeffrey, Paulino, Maricely Ambar Perez Fernandez, Rudeily, Reyes, Lilia Rosa Reyes Guilamo, Ruben, Rivas, Claudia Alejandra Rivas Torres, Ada, Rodríguez, Madelin Tamar Rosario Villa, Eleazar, Santana, Joel, Soto, Nassin, Tactuk, Cristina Kristel Tonos Sardiñas, Raul, Ubinas, Jose, Victoria, Aaron, Villegas, Ricardo, Acra-Tolari, Larissa, Beltran, Luis Fernand Betances, Alejandro, Blaubach, Denisse Idalia Campos Mejía, Nathalia, Capellan, María Fernanda Cedeño Bruzual, Saray Cordero Spencer, Gabriella Cuevas Lantigua, Luis De Jesus, Gabriela, Díaz, Pedro Pablo Díaz Vásquez, Karla, Disla, Jesús Antonio Echavarría Uceta, Paola Irina Eusebio Jimenez, Damaris, Fernandez, Marlin Fernandez Camilo, Jiomar Manuel Figueroa Germosen, Maruel, Fortunato, Leyla Gabriel Fernández, Alicia German Dihmes, Héctor, Herrera, Elizabeth Leon Cuevas, Jose Alejandro Mata, Mirian Mateo De La Cruz, Dolores Mejia De la Cruz, Marcos, Mirambeaux, Fabio Ortiz De La Cruz, Henry, Paulino, Gabriela, Pelletier, Merycarla, Pichardo, Rodriguez Pumarol Próspero Enrique, Julio, Rivas, Ann Stephany Sanchez Marmolejos, Roman Santana Santana, Irina Suero Almanzar, María Magdalena Vásquez Sánchez, Nicolás, Campuzano, José Ricardo Negrete Ocampo, Maria, Armas, Alvaro Santiago LeMarie Guerra, Gustavo León Vizcaya, Omar Ahmed Abdelwahab, Ahmed, O Elmehrath, Mohammed Ezzat Mostafa, Gamal, Amira, Ibrahim, Sallam, Mohamed, Sherief, Ahmed, 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Maher, Hosain, Ahmed, Hossam, Hamza Hussein Aly Salama Aly, Mohamed, Ibrahim, Abdelrahman, Ibrahim, Nourhan, Ibrahim, Noha Mohamed Salah Ibrahim Moussa Hamouda, Monica, Iskander, Islam, Khalifa, Mostafa, Kotb, Nada, Mahmoud, Alaa Mahmoud Abo Shabana, Nora, Mamdouh, Maram, Metwalli, Khaled, Metwally, Mahmoud, Moghazy, Moustafa, Mohamed, Mohamed, Mourad, Esraa, Moustafa, Kamilia, Mubarek, Nour Eldin Nader, Ahmed, Nasser, Samaa, Omar, Mostafa Shehata Qatora, Mohamed, Ragab, Marawan, Ragal, Dina, Ramadan, Rana, Ramadan, Sara, Ramadan, John, Romany, Ahmed, Sabry, Yasmeen, Said, Sara, Salamah, Ahmed Mostafa Saleh, Mona Saleh Mesbah Mohamed Elkaffas, Alaa, Salem, Hashem, Salim, Ahmed, Samih, Ahmed Samir Abdelaal, Ahmed, Shaheen, Yassmeen Sharafeldin Mohammed, Abdelrahman, Shehata, Mohamed, Shemeis, Karim, Shenit, Mennatallah, Sheta, Asmaa, Soffar, Yousef, Tanas, Ahmed, Tarek, Nermin, Yehia, Omar Khaled Mohamed Eid, Ammar Yasser Abdulfattah, Ahmed, Elsaghir, Mohamed Fouad Elganainy, Omar Ibrahim Elsayed, Omar, Elmandouh, Omar, Hamam, Mostafa Ahmed Shehata, Areej, A Abdelaziz, Ahmed, M Abbas, Wael Abd El-Ghani, Hossam Aldein, S Abd Elazeem, Mustafa Abd Elsayed, Ahmed Yassien Abd-Elkariem, Shimaa, Abdalla, Mahmoud, Abdel-Aleem, Khaled, Abdelazeem, Mahmoud, Abdelfattah, Mohammed, Abdelhafez, Mohamed, M Abdelkarem, Ali, Abdelraouf, Lamess, Abdullaha, Hossam, Abubeih, Moaiad Eldin Ahmed, Nagm Eldin Abu Elnga Ahmed, Ahmed, Ahmed, Sarah Ahmed Saad, Sherif, Alaa, Ali, Alhussaini, Abdelrahman Ahmed Abdelrahman Ali, Ibrahim, Ali, Wagdi, Ali, Mohamed Ali Mohamed, Mohamed, Ashraf, Muhammad, Bassiouni, Mohamed, G El-Adawy, Mohammad, El-Sharkawi, Hussein, Elkhayat, Khaled, Elmaghraby, Shady, Elsdfy, Mohamed, Elsharkawy, Almoutaz, Eltayeb, Mohamed Esmat Mohamed, Esraa, Essam, Mahmoud, Fahd, Osama, Farouk, Rabea, Gadelkareem, Ahmed, Ghoneim, Mohammed Hamada Takrouney, Ahmed, Hamdan, Abd El-Rahman Hamed, Ahmad, Hasan, Mohamed Abdelghafor Hassanin, Islam, Hawal, Kerollos, Henes, Mohamed Omar Herdan, Helal, F Hetta, Omar, Ibrahem, Mostafa, Ibrahim, Islam, H Ibrahim, Mahmoud, Kamel, Mohamed, Khallaf, Shrouk, M Elghazaly, Abobakr, Mahfouz, Osman, Mahmoud, Wesam, Mahran, Doha, Mahrous, Abadeer, Marsis, Ayman, Mohamed, Aliae Mohamed Hussein, Amr Mohamed Sayed, Mahmoud, M Mohammed, Ahmed, Mokhtar, Fatma, A Monib, Ahmed, Nageeb, Mariam Albatoul Nageh, Mohammed, Nageh, Nehal Gamal Omar, Abdelrahman, Ragab, Abdelrahman, Ramadan, Abdallah Rashad Temerik, Aya, Sabry, Hadeer, Safwat, Omar, Salah, Ahmed Elhussiny Salah Mahmoud, Ahmed, Saleh, Mahmoud, Sallam, Ahmed, Samir, Reem, Sayad, Esraa, Sayed, Ahmed, S Sedik, Mohammed, Shahine, Antonios, Soliman, Wael, Soliman, Mohamed Gamal Taher, Randa, Wanees, Ebrahim Ahmed Yousof, Ahmed, Youssef, Omar Zein Elabedeen, Ahmed Emad Sayed Hassan, Shrouk Abdel Fattah, Ahmed, Abostate, Samar, Ali, Saad Ali Saad Salama, Mohamed, Allam, Ahmed, Alsadek, Ebrahim, Arafa, Ahmed, Barakat, Mohammed El Sherpiny, Gehad, Elbehairy, Mahmoud, Eleisawy, 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David, Walawah, Makafui, Yigah, Safia, Yussif, Nuna, Jiagge, Emmanuel, Nachelleh, Jane, Acquaye, Kwabena, Agbedinu, Fareeda, Agyei, Akosua, Agyemang-Prempeh, Kwabena, Amo-Antwi, Michael, Amoah, George, Amoah, Yaw, A Amoako, Daniel Gyawu Aning, Frank, Ankobea-Kokroe, Dominic Annor Mintah, David, Anyitey-Kokor, Adu, Appiah-Kubi, Joshua, Arthur, Vincent, Ativor, Isaac, Barnor, Yasmine, Braimah, Regina, Darko-Asante, Anthony, Davor, Mohammed Duah Issahalq, Mawutor, Dzogbefia, Tano, Emile, Papa, Fiifi-Yankson, Valerie, Gaveh, Senyo, Gudugbe, Solomon, Gyabaah, Frank Enoch Gyamfi, Adam, Gyedu, Derrick, Gyimah, Bernard, Hammond, Boakye-Yiadom, Jonathan, Yorke, Joseph, Thomas Okpoti Konney, Anna, Konney, Kwasi, Kusi, Ishmael, Kyei, Agbenya, Lovi, Nuhu, Naabo, Boateng, Nimako, Beauty, Nyadu, Obed Ofori Nyarko, Ben Blay Ofosu-Barko, Philip Peprah Oppong, Anita, Osabutey, Martha, Poku, Robert, Sagoe, Abiboye, Yifieyeh, George, Ansong, Adam, Abass, Alhassan, Abdul-Mumin, Theophilus, Adjeso, John Abanga Alatiiga, Munira, Amadu, Nathaniel, Annan, German Azahares Leal, Mohammed, Bukari, Alexis, Buunaaim, Ernest, Cheyuo, Latif Daboo Salifu, Michael, Damah, Malcolm, Dery, Edem Kojo Dzantor, Odoniel Guerra Garcia, Yabasin Iddrisu Baba, Adamu, Issaka, Abdul-Jalilu Mohammed Muntaka, James, Murphy, Yaa Nyarko Agyeman, Wisdom Opoku Amankwaa, Imoro, Osman, Samuel, Pie, Anwar Sadat Seidu, Mohammed, Sheriff, Ana Maria Simono Charadan, Abraham, Titigah, Mundashiru, Yahaya, Musah, Yakubu, Edwin Mwintiereh Ta-Ang Yenli, Ioannis, Grypiotis, Nikolaos, Kiriakopoulos, Georgios, Koliopoulos, Vasilis, Kyvelos, Georgia, Micha, Triada, Papadopoulou, Dimitrios, Balalis, Evangelos, Fradelos, Dimitrios, Korkolis, Nicholas, Alexakis, Kyveli, Angelou, Dimitrios, Haidopoulos, Anastasia, Prodromidou, Alexandros, Rodolakis, Nikolaos, Thomakos, Dimitris, Psychogios, Pantelis, Antonakis, Konstantinos, Bramis, Leonidas, Chardalias, Ioannis, Contis, Nikos, Dafnios, Dionysios, Dellaportas, Papalouka, Dimitra, 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Liolis, Elias, Ioannis, Maroulis, Francesk, Mulita, Kerasia-Maria, Plachouri, Michail, Vailas, Charalampos, Doitsidis, Eva, Filo, Ioanna, Gkalonaki, Eleni, Kogia, Konstantina, Kontopoulou, Magdalini, Mitroudi, Christina, Panteli, Ioannis, Patoulias, Olga Ioulia Semkoglou, Dimitrios, Sfoungaris, Ioannis, Valioulis, Ioannis, Astreidis, Panagiotis, Christidis, Orestis, Ioannidis, Lydia, Loutzidou, Antonis, Mantevas, Konstantinos, Paraskevopoulos, Dimitris, Tatsis, Apostolos, Athanasiadis, Themistoklis, Dagklis, Ioannis, Kalogiannidis, Georgios, Kapetanios, Apostolos, Mamopoulos, Chrysoula, Margioula-Siarkou, Stamatios, Petousis, Ioannis, Tsakiridis, Christos, Anthoulakis, Chrysanthos, Christou, Antonios, Fantakis, Eirini, Iordanidou, Christos, Kaselas, Sousana, Panagiotidou, Vasileios, Papadopoulos, Kyriakos, Papavasiliou, Athanasios, Piachas, Ioannis, Siasios, Ioannis, Spyridakis, Theodoros, Theodoridis, Andreas, Tooulias, Eleftherios, Tsiridis, Maria, Tsopozidi, María, Alemán, Estuardo, Brolo, Ana Lucia Lemus, Jennifer, Greenberg, Krisna Mishel Morales Chew, José Rodrigo Oliva, María Alejandra De León Lima, Ismar Lopez Muralles, Felipe, Solares, Gaby, Ajcip, Claudia, Anton, Jose, Cojulun, Mario-Andrés, Flores, Noriega, José, Carlos Adolfo Marroquín Paiz, Steffanía, Morales, Ramiro, Najera, Eduardo Quiñónez Lorenzana, Pablo, Rivera, Lesly, Rodas, Victor, Santos, Dianne, Sosa, Natalia, Ybarra, José David Pérez Cajti, Carlos, Régil, Walter, A Osorio, Rember Rosales Arriola, Luis-Fernando, Talé-Rosales, Danilo, Herrera, Servio Tulio Torres Rodríguez, Sergio Alejandro Villeda, Joshua, Anicetti, Andrea Michelle Lowey Medina, Javier, Ardebol, Kathia, Barillas, Francis De Leon, Salvador, Recinos, Miguel-Angel, Marroquin-Alpirez, Yessica, Yax, Sophie, Hon, Yuk Ho Liu, Alex Qinyang Liu, Shirley, Liu, Hei Tung Natalie Chiu, Chi Man Tom Chow, Victor, Hau, Ho Wai Ip, Brian, Mak, Chung Ying Mok, Dennis, Ng, Yin Yu Eva Siu, Kiu Fung Wong, Jingya Jane Pu, Yu-Xiong, Su, Kit Ying Au-Yeung, David Yuen Chung Chan, Albert, Chan, Shannon Melissa Chan, Tsz Ching Chang, Tor Wo Chiu, Wang Kei Chiu, Zhexi, He, Man Fung Ho, Kevin Ki Wai Ho, Jacky Yan Kit Ho, Janet Wui Cheung Kung, Cheuk Ho Lam, Rainbow W, H Lau, Samuel Ka Kin Ling, Hon Ting Lok, Tony Wing Chung Mak, Chi-Fai, Ng, Simon, Ng, Kelvin Kwok-Chai Ng, Calvin S, H Ng, Michael Tim Yun Ong, Teresa, Tan, Sui Fan Tang, Jeremy Yuen-Chun Teoh, Anthony, Teoh, Bess Siu Yan Tsui, George Kwok Chu Wong, Randolph, Wong, Kwok Chuen Wong, Chi Hang Yee, Zsuzsanna, Antal, Attila, Kalman, Peter, Voros, Kiarash, Bahrehmand, Timea, Echim, Zoltan, Novak, Tamás, Sztipits, Laszló Ádám Bihari, László, Hidi, Laszlo, Piros, Balazs, Rózsa, Peter, Sotonyi, Lilla, Szatai, György, Herczeg, Bálint, Pordány, Fanni, Tornyi, Kristof, Dede, Tamás, Egyed, György, Saftics, Judit, Kulcsicka-Gut, Zsófia, Sipos, Dezso, Toth, Bhavin, Patel, Hardil, Majmudar, Saptak, Mankad, Sohilkhan, Pathan, Sharathkumarkl, L, Lokesh, Sasatti, Subramanyam, Mahankali, Santhosh Kumar Sampengere Annayappa, Tulika, Agrawal, Premkumar, Anandan, Aditya, Baindur, Manjunath, Bd, Savitha, C, S Anitha, G, Sandeep, Harigond, K Tejeswini, K, Venkatesh, Kesarla, Mallikarjuna, Manangi, B Hareesh, P, Jyothi K, R Ranjan, Athish, Shetty, Santhosh Shivashankar Chikkanayakanahalli, Tanvi, Sunil, Shreya, Syamala, Kavya, Tharanath, Aditya, Atal, Niranjana, Rajagopal, S Srinath, B, Vinod, Nk, L Thirumanikandan, P, Nitu, Mishra, Sushruta, Shrivastava, Rekha, Wadhwani, Reyaz, Ahmad, Zainab Ahmad Haq, Prateek, Behera, Ritika, Dhurwe, Rehan, Haq, Vaibhav, Jain, Anuj, Jain, Sunaina, Karna, Kameshwarachari, Pushpalatha, Sumit, Raj, John Ashutosh Santoshi, Pooja, Singh, Virendra, Verma, Vaishali, Waindeskar, Moorat Singh Yadav, Zaheda, Aziz, Koyel, Chakraborty, Preetam, Chappity, Gurudip, Das, Debajyoti, Datta, Saubhagya Kumar Jena, Madhabananda, Kar, Susanta, Khuntia, Pankaj, Kumar, Ravi, Kumar, Aswathi, Kv, Abhijeet, Mishra, Swastik, Mishra, Yash, Mittal, Dillip, Muduly, 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Somil, Jaiswal, Yashpal, Jaware, Navneet, Kala, Ruchi, Karnatak, Apjit, Kaur, Vijay, Kumar, Manoj, Kumar, Ambrish, Kumar, Upander, Kumar, Amit Kumar Shrivastava, Seema, Mehrotra, Brijesh, Mishra, Anand, Mishra, Namrata, Bal Krishna Ojha, Ahmad, Ozair, Uma Shanker Pal, Amita, Pandey, Nancy, Raja, Pooja, Ramakant, Ashutosh, Roy, Rekha, Sachan, Satyanarayan, Sankhwar, Pushp, Sankhwar, Divya, Sarin, Ayushi, Shukla, Sushil, Singh, Mohit, Singh, Kul Ranjan Singh, Renu, Singh, Uma, Singh, Urmila, Singh, Vandana, Solanki, Abhinav Arun Sonkar, Chhitij, Srivastava, Parijat, Suryawanshi, Vivek, Tewarson, Rajat, Verma, Manju Lata Verma, Awdhesh, Yadav, Gyan, Chand, K M, M Vishvak Chanthar, Dileep, Hoysal, Anjali, Mishra, Nitin, Batra, Arun, Bhatti, Rupali, Chopra, Shakina, David, Tapasya, Dhar, Uma Kant Dutt, Rohini, Dutta, Sumir, Gandhi, Parvez David Haque, B Paul Sudhakar John, Sreejith Kannummal Veetil, Gurvinder, Kaur, Navneet, Kumar, Anil, Luther, Anupam, Mahajan, Amit, Mahajan, Kavita, Mandrelle, Shefin, Mathews, Vishal, Michael, Partho, Mukherjee, Pinki, Pargal, Rajesh, Paul, Anupam, Phillip, Rachel, Phillips, Abhishek, Samuel, Noel, Singh, Inderjot, Singh, Abhijit, Singh, Sarvpreet Singh Grewal, Anusha, Singhania, Selven, Thirumalai, Ashish, Varghese, Joshua, Wesley, Josy, Thomas, Pradeep, Zechariah, Mariam Anjum Ifthikar, Rohan Thomas Mathew, Rohan, Shetty, M Vijayakumar Vijaykumar, Bm Zeeshan Hameed, Sufyan, Ibrahim, Gayathri, Jyothish, Sunil, Krishna, Stanley, Mathew, Arjun Suresh Kumar, Narinder, Singh, Piyush Kumar Sinha, Rachith, Sridhar, Sunny, Agarwal, Srikant, Balasubramaniam, Swati, Chhatrapati, Charulata, Deshpande, Ashni, Dharia, Sarita, Fernandes, Suraj, Gandhi, Mangesh, Gore, Abhilash, Jayakumar, Rameshwar, Mhamane, Anand, Nirgude, Sandesh, Parab, Manish, Patil, Amit, Peswani, Anjana, Sahu, Sarika, Samel, Fagun, Shah, Dipti, Haridas, Vijay, Shetty, Bejoy, Abraham, Varun, Agarwal, Quazi, Ahmad, Ashishkumar, Asari, Mohammad Ismail Attar, Nagaraja Sekhar Ayyalasomayajula, Sutej, Bachawat, Shivani, Bachhav, Vivek, Badhe, Sanjiv, Badhwar, Shubhabrata, Banerjee, Vikas, Basa, Vipul, Bothara, Somnath, Chattopadhyay, Sohin, Chaudhari, Rahul, Chavan, Priyank, Chawathe, Shailja, Dadhich, Anuj, Dalal, Avinash, Date, Mandar, Deshpande, Preetham, Dev, Niren, Dongre, Anirudha, Doshi, Maya, Gade, Shreyash, Gajjar, Mohan, Gawande, Amol, Ghalme, Bhavisha, Ghugare, Ishita, Gupta, Manoj, Jain, Divakar, Jain, Saumya Sekhar Jenasamant, Vaishali, Joshi, Vinay, Joshi, Neha, Kalwadia, Nandkishore, Kapadia, Hari Bipin Radhakrishnan Kattana, Tirathram, Kaushik, Akshat, Kayal, Shama, Kovale, Yogesh, Kulkarni, Abhaya, Kumar, Kranthi, Kumar, Kashmira, Kumawat, Vidyadhar, Lad, Namrata, Maskara, Rajesh, Mistry, Smruti Ranjan Mohanty, Kanchan, Motwani, Manoj, Mulchandani, Mandar, Nadkarni, Sanjay, Pandey, Mrunal, Parab, Dinshaw, Pardiwala, Amrita, Patkar, Neha, Pawar, Abhijit, Pawar, Abhinav, Pednekar, Vishal, Peshattiwar, Harshwardhan, Pokharkar, Ojas, Potdar, 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Reddy Voppuru, Anushri, Soni, Gira, Soni, Junaid, Alam, Dinesh, Bagaria, Minu, Bajpai, Akshay Kumar Bisoi, Arvind, Chaturvedi, Sandeep, Chauhan, Narendra, Choudhary, Rajendra Singh Chouhan, Sunil, Chumber, Kamran, Farooque, Vasubabu, Gudala, Amit, Gupta, Mohit, Joshi, Apoorva, Kabra, Shashank Sharad Kale, Abhinav, Kumar, Subodh, Kumar, Dhruv, Mahajan, Rajesh, Malhotra, P Ramesh Menon, Biplap, Misra, Samarth, Mittal, Rajinder, Parshad, Pratyusha, Priyadarshini, Sushma, Sagar, Pradeep Brijkishor Sharma, Vijay, Sharma, Vivek, Trikha, Mayank, Tyagi, Kuldeep, Bansal, Kalyan, Varma, Anurag, Mishra, Rajdeep, Singh, Rohit, Bhardwaj, Abhishek, Mittal, Sabarirajan, Ponnusamy, Gyan Ranjan Singh, Isha, Tuli, Pramod, Bhor, Sanjay, Dhar, Sachin, Kale, Manisha, Aggarwal, Himani, Gupta, Gurleen, Kaur, Ajinkya, Deshpande, Anup, Gadekar, Tanmay, Jaysingani, Taufiq, Panjwani, Rakesh, Patil, Narendra, Vaidya, Sunil Kumar Vishwakarma, Utkarsha, Wayal, Debnarayan, Dutta, Rajnish, Arora, Mohit, Dhingra, Pankaj Kumar Garg, Farhanul, Huda, Pankaj, Kandwal, Ravi, Kant, Rajkumar Kottayasamy Seenivasagam, Navin, Kumar, Shashank, Kumar, Lokavarapu Manoj Joshua, Radheyshyam, Mittal, Dharma Ram Poonia, Deepak, Rajput, Saravanan, Sadhasivam, Sudhir, Singh, Vivek, Singh, Kshitija, Chandanwale, Melissa, Philip, Vaibhav, Thorat, Yousuf, Choudhury, Devishmita, Das, Mautushi, Das, Subhadra, Goala, Farhana Yasmin Laskar, Parbin, Laskar, Kapil, Malik, Poulome, Mukherjee, Abhishek, Sarkar, S Thoibisana Singha, M Nongalei Singha, Damayanti, Singha, Gowtham, Srungavarapu, Ritesh, Tapkire, Siempui, Tling, Syed Muzamil Ishaq Andrabi, Gowhar Aziz Bhat, Nisar, Chowdri, Robindera, Kour, Fazl, Parray, Raahil, Shah, Zamir Ahmad Shah, Rauf, Wani, Soujanya, Adamala, Ravikanth, Gowder, Siddhi, Hegde, S Mashitha, M, Shreya, Sreeram, Sushil, Ankadavar, Darshan, Bafna, Bharat, Dhanani, Nikhil, Ingle, Piyush, Jadhao, Sinu, Joseph, Swapnil, Kapote, Shirin, Karkada, Parag, Lad, Rajan, Lohia, Suyog, Madje, Venkateshwaran, Narasiman, Meer, Chisthi, Gejoe, George, Harihara, Jothi, Dilber, Pareed, Godwin David, C Mathew, Livingston, Abel, Mansi, Agrawal, Rabindranath, B, Manish, Baldia, Ravi Kishore Barla, Manisha, Beck, Santosh, Benjamin, Jeremy, Bliss, Lisa, Cherian, Sreekar, Devarakonda, Geley, Ete, Arun Jacob Philip George, Amish, Gohil, Deeptiman, James, Mark Ranjan Jesudason, Lallu, Joseph, Treasa, Joseph, Kathir, Joyson, Gomathi, Karnan, Albert, Kota, Pushplata, Kumari, Anitha, Loganathan, Vasanth Mark Samuel, John, Mathew, Senthil, K Nathan, Joby Elizabeth Ninan, Ajay, Philip, R Priyadarshini Priyadarshini, Suganya, S, Habie, Samuel, Gilbert, Samuel, Daniel, Selvaraj, Srujan, Sharma, Suraj, Surendran, D Hariharan, T, Santhosh Kumar Thangaraj, Vinotha, Thomas, Varghese, Thomas, John, K Thomas, S Harish, Y, Manobhiram, Boggavarapu, Murali Krishna Voonna, Marilaeta Cindryani Lolobali, Christopher, Ryalino, Tjokorda Gde Agung Senapathi, Mahadewa, Tjokorda, I Made Gede Widnyana, Dita, Aditianingsih, Aino, Auerkari, Susilo, Chandra, Fachreza Aryo Damara, Mohammad Adya Firmansha Dilmy, Achmad Kemal Harzif, Sidharta Kusuma Manggala, Dedy, Pratama, Affan, Priyambodo, Andi Ade Ramlan, Ratna Farida Soenarto, Adhrie, Sugiarto, Ilham Utama Surya, Tamara, Tango, Aida Rosita Tantri, Raihanita, Zahra, Dedy, Fachrian, Andi, Hasyim, Ade, Susanti, Teddy, Saputra, Erwin, Syarifuddin, Andi Asadul Islam, Hendra, Pajan, Ahmad Hannan Amrullah, Khoirul, Anam, Thirza, Hadipranata, Julius Albert Sugianto, Aidyl, Fitrisyah, Mayang Indah Lestari, Nur Rachmat Lubis, Rizal, Zainal, Zulkifli, Zulkifli, Erick Gamaliel Amba, Warren, Lie, Andika Adiputra Thehumury, Tedy, Apriawan, Yunus Kuntawi Aji, Roidah Taqiyya Zahra Wathoni, Sumadi Lukman Anwar, Teguh, Aryandono, Wirsma Arif Harahap, Juni, Kurniawaty, Djayanti, Sari, Artanto, Wahyono, Yunita, Widyastuti, Akhmad Yun Jufan, Parisa, Arjmand, Mohammad, Etezadpour, Babak, Ganjeifar, Masoumeh, Hosseinpoor, Hassan, Mehrad-Majd, Mohsen, Rajati, Reza, Assadi, Ehsan, Noori, Parisa, Rajaei, Samira, Hajisadeghi, Mohammad, Mehdizadeh, Mina, Soltani, Narges, Alizadeh, Gholamreza Azarnia Azar Nia, Hamid, Heidari, Seyedmohamad Hosseini Zavareh Hosseini Zavareh, Ali Moazami Pour Moazami Pour, Farokh, Savaddar, Mostafa, Vahedian, Hoora, Amouzegar, Mojdeh, Bahadorzadeh, Seyedeh Homa Hemmasi, Ahmad, Kachoie, Ali Karimi Karimi, Sepideh, Miraj, Monireh, Mirzaie, Hossein Mokarami Mokarami, Amrollah, Salimi, Roghayyeh, Ahangari, Ali, Ahmadvand, Ali, Bashiri, Morteza, Borhani, Mohammad, Haidari, Mohammad Taghi Imani Khosroshahi, Shahrokh Jahan Bini, Mohsen, Koosha, Mohammad Kazem Moslemi, Ali, Naghibi, Shahrzad, Tehrani, Zahra, Yazdi, Seyyed Hassan Adeli, Majid, Alborzi, Hamed, Bagheri, Mohsen, Eshraghi, Hassan Fatemi Manesh, Mohammad, Ghomeisi, Seyed Fakhreddin Hejazi, Saeed, Madani, Nima Najafian Motahaver, Samieh, Norouzi, Mahdi Pezeshki Modarres, Ali, Shafiee, Jamshid, Vafaeimanesh, Hossein, Yusefi, Elahe, Hosseini, Pourya, Medhati, 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Marshall, Darya, Musa, Zeeshan, Ahmad, Emmet, Andrews, Bruno Chan Chin, Mark, Corrigan, Amy Edwards Murphy, Niamh, Foley, Padraig, Gardiner, Daniel, Hechtl, Michelle, Hsiao, Mohd Yasser Kayyal, Shane, Killeen, Maria, Lyons, Cathy, Burke, Matt, Hewitt, Marwa, Mohamed, Syeda Farah Nazir, Mei Yee Ng, Nor Azlia Abdul Wahab, Cathy, Monteith, Oladayo, Oduola, Lylas, Aljohmani, Timothy, Nugent, Paula, Corr, Lauren, Crone, Johnathon, Harris, Arnold, Hill, David, Kearney, Robert Anthony Keenan, Deirdre, Nolan, James, Ryan, Mark Philip Hehir, Carmen, Regan, Michael, Geary, Fergal, Malone, Claire, Mccarthy, Donal, B O'Connor, Shane, Considine, Emma, Donohoe, Caroline, Herron, John, Larkin, Thomas Hugh Lynch, Barry, Maguire, Rustom, Manecksha, Andrea Mc Carthy, Katharina, Nagassima, Erica, O'Sullivan, Pat, Rohan, Ryan, Roopnarinesingh, Salloum, Salloum, Thomas, Aherne, Mary, Barry, Gareth John Bowen, Ellen, Boyle, Joseph, Dowdall, Ann, Hanly, Ahmed, Hassanin, Helen, Heneghan, Conor, Hurson, Orlaith, Kelly, Rory, Kennelly, Aoife, Kiernan, Sean, T Martin, Nawar, Masarani, Damian, Mccartan, Enda, W McDermott, Ben, Murphy, Kin Cheung Ng, Nwabundo, Njeze, Aine, O'Neill, Ruth, S Prichard, Ned, Quirke, Ian Sean Reynolds, Des, Winter, Rowan, Casey, Mutaz, Elamin, Amy, Gillis, Dara, Kavanagh, Michael, Kelly, Áine, Mcnamee, Paul, Neary, Patrick, Owens, Akshaya, Ravi, Paul, Ridgway, Paul, Carroll, Chris, Collins, Amenah, Dhannoon, Amy, Fowler, Aisling, Hogan, Aoife, Lowery, Peter, Mcanena, Charlie, Timon, Stewart, Walsh, Wisam, Al-Ramli, Imran, Azeem, Muhammad Usaama Bahadoor, Zsolt, Bodnar, Hassan, Elmusharaf, Faisal Saeed Hassan, Adam, Hingum, Huilun, Huan, Seamus, Jennings, Mohamed Hamed Khalid, Mariya, Kuteva, Syed Nadeem Mujtaba, Shanell, Peeriyah, Hina, Rehman, Muhammad Assam Sarwar, Tony, Shaju, Ian, Stephens, Michael, Sugrue, Joseph, Thomas, Manvydas, Varzgalis, Saqib, Zeeshan, Alisha, Jaffer, Larne, Jones-Whiting, Colin, Peirce, Sean, Johnston, Seantee, Lim, Alwaleed, 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Massimiliano, Gennaro, Lorenzo, Giannini, Marcello, Guaglio, Marco, Guzzo, Andrea, Leva, Alberto, Macchi, Elena, Manzo, Fabio, Martinelli, Ilaria, Mattavelli, Vincenzo Maria Mazzaferro, Francesco, Raspagliesi, Luigi, Rolli, Laura, Sala, Roberto, Salvioni, Mario, Santinami, Silvia, Segattini, Luca, Sorrentino, Carlotta, Zaborra, Alexandre, Anesi, Gianmaria Casoni Pattacini, Mattia Di Bartolomeo, Francesca, Pecchini, Arrigo, Pellacani, Micaela, Piccoli, Federico, Fusini, Andrea, Gattolin, Marco, Migliore, Roberto, Rimonda, Diego, Sasia, Elisabetta, Travaglio, Federica, Brunetti, Marco, Cereda, Marco, Ceresoli, Luca, Cigagna, Cristina, Dell'Oro, Alessandro, Fogliati, Robert, Fruscio, Tommaso, Grassi, Maini Marzia Isabella, Luca Carlo Nespoli, Massimo, Oldani, Sara, Ornaghi, Nicolò, Tamini, Carmine, Antropoli, Antonio, Castaldi, Alessio, Palumbo, Gaia, Altieri, Umberto, Bracale, Francesco, Corcione, Marcello De Luca, Giovanni Domenico De Palma, Maria Michela Di Nuzzo, Ruggero, Lionetti, 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Matteo, Filardo, Marika Sharmayne Milani, Franco, Ragni, Andrea de Manzoni Garberini, Edoardo, Baldini, Diana, Carpaneto, Michele, Cauteruccio, Corrado, Ciatti, Luigi, Conti, Serena, Gattoni, Pietro, Maniscalco, Gerardo, Palmieri, Calogero Puma Pagliarello, Giuseppe, Caristo, Raffaele, Galleano, Michele, Malerba, Marcello, Calabrò, Francesca, Farnesi, Elia Giuseppe Lunghi, Andrea, Muratore, Nicoletta Sveva Pipitone Federico, Joel Reuben Abel, Lorenzo, Andreani, Darienzo, Antonio, Vittorio, Aprile, Riccardo, Balestri, Giacomo, Benettini, Stefano, Berrettini, Luca, Bruschini, Massimo, Chiarugi, Federico, Coccolini, Simone, Colangeli, Camilla, Cremonini, Lodovica Cristofani Mencacci, Iacopo, Dallan, Silvia De Santi, Gregorio Di Franco, Lorena Di Girolami, Giacomo, Fiacchini, Niccolò, Furbetta, Stylianos, Korasidis, Marco, Lucchi, Andrea, Morandi, Luca, Morelli, Serena, Musetti, Carlo Maria Neri, Matteo, Palmeri, Miriana, Picariello, Francesco, Porcelli, Marco, Puccini, Nicolo, Roffi, Erica, Statuti, Dario, Tartaglia, Alberto, Tonelli, Matteo, Vianini, Gianluca, Baronio, Mauro, Montuori, Enrico, Pinotti, Stefano Maria Massimiliano Basso, Federica, Maffeis, Paolo, Ubiali, Lorenzo, Aguzzoli, Saverio, Coiro, Giuseppe, Falco, Vincenzo Dario Mandato, Valentina, Mastrofilippo, Simone, Mele, Caterina, Baldi, Carlo, Corbellini, Gianluca Matteo Sampietro, Massimo, Dugo, Mauro, Garino, Chiara, Marafante, Antonio, Masciandaro, Elisabetta, Moggia, Alessandra, Murgese, Felice Eugenio Agro, Gabriella Teresa Capolupo, Filippo, Carannante, Marco, Caricato, Vincenzo, Denaro, Erica, Mazzotta, Rocco, Papalia, Giuseppe, Pascarella, Alessandro, Strumia, Biagio, Zampogna, Matteo, Cinquepalmi, Marco, Colasanti, Celeste Del Basso, Federica, Falaschi, Nicola, Guglielmo, Roberto Luca Meniconi, Alessandra, Pecoraro, Sofia, Usai, Giacomo, Crescentini, Antonella, Larcinese, Emanuele, Picone, Giovanni, Sinibaldi, Annamaria, Agnes, Salvatore, Agnes, Sergio, Alfieri, Francesco, Belia, Valentina, Bianchi, Giuseppe, Bianco, Alberto, Biondi, Paola, Campennì, Valerio, Cozza, Sabatino, D'Archi, Domenico, D'Ugo, Veronica De Simone, Marta Di Grezia, Sofia Di Lorenzo, Federica, Ferracci, Valeria, Fico, Gianluca, Franceschini, Pietro, Fransvea, Giulio, Gasparini, Luca, Gordini, Antonio La Greca, Francesco, Litta, Celestino Pio Lombardi, Angelo Alessandro Marra, Angelo, Parello, Marco Maria Pascale, Romeo, Patini, Gilda, Pepe, Roberto, Persiani, Caterina, Puccioni, Carlo, Ratto, Fausto, Rosa, Gianmarco, Saponaro, Lorenzo, Scardina, Tedesco, Silvia, Giuseppe, Tropeano, Maria, Benevolo, Daniele, Bugada, Flaminia, Campo, Maria Gabriella Dona, Valentina, Manciocco, Paolo, Marchesi, Riccardo, Mastroianni, Francesco, Mazzola, Silvia, Moretto, Raul, Pellini, Gerardo, Petruzzi, Barbara, Pichi, Giuseppe, Simone, Gabriele, Tuderti, Jacopo, Zocchi, Luigi Marino Cosentino, Andrea, Sagnotta, Roberta, Angelico, Vittoria, Bellato, Michela, Campanelli, Marzia, Franceschilli, Michele, Grande, Giorgio, Lisi, Tommaso Maria Manzia, Lorenzo, Petagna, Bruno, Sensi, Giuseppe, Sica, Leandro, Siragusa, Giuseppe, Tisone, Marco, Assenza, Barbara, Binda, Massimo, Biondi, Gioia, Brachini, Placido, Bruzzaniti, Mauro, Casagrande, Flavia, Ciccarone, Pierfranco Maria Cicerchia, Bruno, Cirillo, Daniele, Crocetti, Giancarlo, D'Ambrosio, Vito, D'Andrea, Francesca De Felice, Giorgio De Toma, Carlo Della Rocca, Giulia, Duranti, Pietro, Familiari, Enrico, Fiori, Giovanni Battista Fonsi, Alessandro, Frati, Stefania La Rocca, Filippo La Torre, Pierfrancesco, Lapolla, Giovanni, Marruzzo, Simona, Meneghini, Andrea, Mingoli, Andrea, Picchetto, Antonella, Polimeni, Diego, Ribuffo, Maurizio, Salvati, Antonio, Santoro, Paolo, Sapienza, Luigi, Simonelli, Valentino, Valentini, Martina, Zambon, Giuseppa, Zancana, Emma, Zuppi, Simone, D'Annunzio, Cosimo De Nunzio, Silvia, Fiorelli, Mohsen, Ibrahim, Chiara, Loffredo, Domenico, Massullo, Cecilia, Menna, Rocco, Monica, Massimiliano, Pelli, Erino Angelo Rendina, Leonardo, Teodonio, Andrea, Tubaro, Giulio, Argenio, Giulio, Accarino, Accarino, Giancarlo, Antonio Nicola Giordano, Luca, Cardinali, Elisa, Sebastiani, Grazia, Travaglini, Erika, Andreatta, Emanuele Luigi Giuseppe Asti, Daniele, Bernardi, Luigi, Bonavina, Caterina, Froiio, Andrea, Lovece, Chiara, Copelli, Alfonso, Manfuso, Pasquale Di Maio, Marco, Giudice, Oreste, Iocca, Rosario, Cennamo, Tommaso, Cornali, Francesco Di Marzo, Cristian, Altana, Francesco, Bussu, Giampiero, Capobianco, Anna Giacomina Carta, Sandro, Ciccarello, Maria Laura Cossu, Pietrina, Cottu, Giacomo De Riu, Salvatore, Dessole, Francesco, Dessole, Salvatora, Dettori, Carlo, Doria, Alessandro, Fancellu, Claudio, F Feo, Giorgio Carlo Ginesu, Giuliana, Giuliani, Marco Giuseppe Iannuccelli, Massimo, Madonia, Roberto, Mancino, Olindo, Massarelli, Gianfranco, Meloni, Fabio, Milia, Andrea, Mulliri, Teresa, Perra, Marco, Petrillo, Antonio, Piras, Franco, Piredda, Francesco, Pisanu, Alberto, Porcu, Davide, Rizzo, Angelino, Sanna, Antonio Mario Scanu, Fabrizio, Scognamillo, Damiano, Soma, Anna Rita Tanca, Alessandro, Tedde, Matteo, Tedde, Luigi Angelo Vaira, Andrea Bartalini Cinughi de Pazzi, Osvaldo Carpineto Samorani, Daniele, Fusario, Luigi, Marano, Gaia, Oldrà, Anna Lisa Pesce, Stefania Angela Piccioni, Luca, Resca, Vincenzo, Ricchiuti, Franco, Roviello, Vinno, Savelli, Alberto, Abrate, Pierpaolo, Bordoni, Lorenzo, Bosio, Guglielmo, Clarizia, Francesco, Fleres, Marco, Franzini, Antonio, Fratto, Pierluigi, Giumelli, Alessandro, Grechi, Alessandro, Longhini, Fabrizio, Lorusso, Elisa, Scarnecchia, Federica, Scolari, Alessandro, Spolini, Vincenzo, Maiuri, Matteo, Papandrea, Arturo, Roncone, Lorenzo, Conti, Andrea, Rizzi, Marco, Rovagnati, Alberto, Brolese, Tommaso, Cai, Francesco Antonio Ciarleglio, Francesca, Dalprà, Gianni, Malossini, Liliana, Mereu, Irene, Tamanini, Saverio, Tateo, Giovanni, Viel, Enrico, Battistella, Paolo Boscolo Rizzo, Cristoforo, Fabbris, Marco, Massani, Giacomo, Spinato, Roberta, Tutino, Ugo, Grossi, Alessandro, Iacomino, Simone, Novello, Maurizio, Romano, Serena, Rossi, Giulio, Santoro, Giacomo, Zanus, Sokol, Trungu, Giada, Aizza, Gabriele, Bellio, Selene, Bogoni, Marina, Bortul, Biagio, Casagranda, Sara, Cortinovis, Nicolò de Manzini, Davide, Drigo, Paola, Germani, Manuela, Mastronardi, Lucia, Paiano, Silvia, Palmisano, Pier Luigi Filosso, Francesco, Guerrera, Matteo, Marro, Mauro, Rinaldi, Enrico, Ruffini, Stefano, Salizzoni, Laura, Bardelli, Mattia, Berselli, Giacomo, Borroni, Eugenio, Cocozza, Matteo, Desio, Bottazzoli, Elisa, Giuseppe, Ietto, Valentina, Iori, Domenico, Iovino, Lorenzo, Livraghi, Valentina, Marchionini, Stefano, Megna, Emma Amal Nahal, Mara, Palumbo, Valeria, Quintodei, Alessandra, Zullo, Lucrezia, D'Alimonte, Giovanni, Pirozzolo, Chiara, Vignotto, Tommaso, Campagnaro, Andrea, Caravati, Simone, Conci, Carlotta De Cristofaro, Gabriele, Gecchele, Tommaso, Giuliani, Jacopo, Graziosi, Alfredo, Guglielmi, Salvatore, Paiella, Corrado, 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Rakotoarisoa, Maharo, Ramifehiarivo, Solonirina Harinarindra Ranaivoson, Hajamihamina Marina Parfaite Randriantsoa, Narindra Njarasoa Mihaja Razafimanjato, Jeannie Ba Razafindrahita, Solofoarimanana, Solofoarimanana, Guillaume Odilon Tsiambanizafy, Rakotonaivo Mamisoa Judicaël, Corinne Eulalie Solo, Tojomamy Herinjaka Ralaizafindraibe, Fanonjomahasoa Safiry Andofenohasina, Hanta, Rasataharifetra, Vanona Barijaona Razafindraibe, Angelin Sablon Herinirina, Andre, Das, Thanga, Ganapathy, Yohesuwary, Gunarasa, Kalyani, Mariapan, Maathichsudhaar, Muniandy, Mohd Firdauss Osman, Mohd Azem Fathi Mohammad Azmi, Jien Yen Soh, Wan Zainira Wan Zain, Andee Dzulkarnaen Zakaria, Zaidi, Zakaria, Kheng Hooi Chan, Firdaus, Hayati, Syamim, Johan, Jin Jiun Mah, Ratha Krishnan Sriram, Sentilnathan, Subramaniam, Nur Shahirah Binti Muhammad Shahimi, Khairul Hazim Hamdan, Mohd Razali Ibrahim, Guhan, Muthkumaran, Ju Ann Tan, Mohana Raj Thanapal, Dayang Anita Abdul Aziz, Mae-Lynn, Bastion, Mohd Hairul Nizam Harun, Farrah-Hani, Imran, Norshamsiah Md Din, Ayesha Mohd Zain, Mushawiahti, Mustapha, Syed, Nabil, Ainal Adlin Naffi, Abd Jabar Nazimi, Roszalina, Ramli, Bee Hong Soon, Pavin, Bal, Joo Qing Cheng, Mohd Rusdi Draman, Ahmad Nazran Fadzli, Sakina, Ghauth, Weipin, Hung, Suniza, Jamaris, Peng Soon Koh, Sivakumar, Krishnasamy, Yeong Sing Lee, Yew Toong Liew, Jeffery Zk Lim, Raymond Chung Siang Lim, Hiong Chin Lim, Siti Farhan Moh Pauzi, Shireen Anne Nah, Ashvin Krishna Nair, Doris Sin Wen Ng, Yuki Julius Ng We Yong, Kamarajan, Ramayah, Rahmah, Saaid, Anand, Sanmugam, Mee Hoong See, Kanesh Kumaran Seevalingam, Neha, Sethi, Srihari, Singaravel, Syeda Nureena Syed Jafer Hussain Zaidi, Chu Yik Tang, Li Ying Teoh, Kian Boon Wong, Ruben, Xavier, Ahmad Shuib Yahaya, Norhafiza, Ab, Rahman, Islah Munjih Ab, Rashid, Mohd Fahmi Abd Aziz, Mohd Norhisham Azmi Abdul Rahman, Nasser Muhammad Amjad, Shahidah Che Alhadi, Faisal, Elagili, Mohd Nazli Kamarulzaman, Azmi Md Nor, Ahmad Faidzal Othman, Mohd Yusof Sainal, Mat Salleh Sarif, Richelle, Chua, Aini Fahriza Ibrahim, Abdul Rauf Bin Ahmad, Yii Ling Lau, Ka Yee Liew, Kandasami, Palayan, Hui Yu Wong, Jasiah, Zakaria, Nor Azimah Abd Aziz, Norazila Abdul Rahim, Noorneza Abdul Rahman, Bahiyah, Abdullah, Mohamed Faizal Bin Sikkandar, Fatin, Firman, Nik Mohd Hazleigh, Intan Kartika Kamarudin, Shahril, Khalid, Mohd Fairudz Mohd Miswan, Akmal Zulayla Mohd Zahid, Norasyikin, Mustafa, Kadhim, Obaid, Mohd Yusoff Bin Yahaya Yahaya, Ahmad Ramzi Yusoff, Predrag, Andrejevic, Jeremy Borg Myatt, Svetlana, Brincat, Clifford, Caruana, Kurt Lee Chircop, Francesca, Chircop, Daniel Mario Chircop, Charles, Cini, Viktoria, Czok, Melanie, Farrugia, Gabriella, Grima, Fatimah Mj Hassan Almukhariq, Esther, Muscat, Darryl, Pisani, Mohsin Hassan Khan Roshan, Nicholas, Schembri, Mohamed, Shoukry, Neville, Spiteri, Gilbert, Tanti, Ziad Aboharp Hasan, Alberto Bazan Soto, Cedillo Rodrìguez Jonathan Rubén, Gustavo Esteban Lugo Zamudio, David Gerardo Miranda Gómez, José Alfredo Pérez Meave, Victor Pinto Angulo, Antonio Rojas Aguilar, Erik Efrain Sosa Duran, Alejandro Vàzquez Perez, Diego, Arroyo, Jose, Corona-Cruz, Hector, Martinez-Said, Heriberto, Medina-Franco, Manuel, Mendez, Teresa Moreno, Y Suárez Ma, Dolores Orta Díaz, Martha Patricia Pérez de León Vázquez, Angélica Azucena Soto Carvajal, Fidel Soto Hernández, Juan Ignacio Stenner, Adriana Valenzuela López, Mauricio Rene Hernandez, Rey Jesus Romero, Aldo Bernal Hernandez, Ana Olivia Cortes-Flores, Carlos Jose Zuloaga Fernandez Del Valle, Carlos Andres Colunga Tinajero, Jaime, Orozco-Perez, Laura Gabriela Peña Balboa, Guillermo, Yanowsky-Reyes, Víctor Hugo Alcalá Torres, Francisco José Barbosa Camacho, Irma Valeria Brancaccio Perez, Miguel Angel Calderon-Llamas, Aldo Camacho Gomez, Edgar-Joaquin, Cortes-Torres, Esteban, Cueva-Martinez, Oscar Durán Anguiano, Isaac Esparza Estrada, Roberto, Fierro-Rizo, Paola Flores Becerril, Clotilde Fuentes Orozco, Miguel García Castillo, Alejandro Gonzalez Ojeda, Ana Sofia Gonzalez Rubio, Erick Alonso González-García de Rojas, Luis Humberto Govea-Camacho, Jose Aldo Guzman Barba, Juan Carlos Ibarrola Peña, César Íñiguez Martínez, Francisco Javier Llamas-Macias, Ruben Eduardo Morán Galaviz, Cesar, Nuño-Escobar, Oscar-Everardo, Olvera-Flores, Jaqueline, Osuna-Rubio, Jose Victor Pérez-Navarro, Rodrigo, Prieto-Aldape, Luis Ricardo Ramirez Gonzalez, Marco Vinicio Ramírez Sánchez, Emilio, Reyes, Olaya Moramay Romero-Limón, Carlos Beas Ruiz-Velasco, José Antonio Sánchez Martínez, Guillermo, Sanchez-Villaseñor, Ismael, Sedano-Portillo, Gabriela Ambriz Gonzalez, Pedro Berrones Moreno Berrones Moreno, Ana Beatriz Calderon Alvarado, José de Jesús Cárdenas Barón, Araceli, Hernández, Francisco Javier León Frutos, Edgard Efren Lozada Hernandez, Eduardo Morales Valencia, Karla Daniela Pérez, Francina, Bolanos-Morales, Julio, Herrera-Zamora, Patricio, Santillan-Doherty, David Omar Arriaga Zavala, Salvador Francisco Campos Campos, Lizette, Carmona, 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Alexander, Borgstein, Suzanne, Gisbertz, Sarah, Mikdad, Mark van Berge Henegouwen, Roel, Bakx, Marc, Besselink, Daniel Hl Lemmers, Anne-Jasmin, Roelofs, Paul van Amstel, Claire van Helsdingen, Ludi, Smeele, Niels, Harlaar, Frederik, Jonker, Sjirk van der Burg, Justin, Y van Oostendorp, Saranda, Ombashi, Tim van der Voort, Martijn van Geldorp, Lisanne, Posma-Bouman, Hans Donald de Boer, Annette, Olieman, Henriette, Smid-Nanninga, Jean-Paul P, M De Vries, Rianne, Hogenbirk, Tyche, Derksen, Josephine, Franken, Steven, Oosterling, Peter, Nolte, Jelle van der List, Ian, Alwayn, Okker, Bijlstra, Andries, Braat, Ruth, Bulder, Michèle de Kok, Robin, Faber, Ben, Goudsmit, Jaap, Hamming, Sven, Mieog, Alexander, Vahrmeijer, Fenna E, M van de Leemkolk, Joost van der Vorst, Jan van Schaik, Merel, Verhagen, Kim, Albers, Larsa, Gawria, Harry Van Goor, Michiel, Warle, Tessa, M van Ginhoven, Charlotte, Viëtor, Evert-Jan, Boerma, Lara, Lallitsch, Donald, Schweitzer, Wouter, Leclercq, Julie, Sijmons, 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Asensio, Luis Asensio Gomez, Diego, Carrion, Nuria, Chavarrias, Alvaro de Arriba, Jose Antonio Gazo Martínez Gazo, Alberto Gegúndez Simón, Juan Gómez Rivas, Natalia Gonzalez Alcolea, Carolina, Gonzalez-Gomez, Sara Gortázar de Las Casas, María Alexandra Heras Garceau, Alicia Hernández Gutierrez, Luis, Lassaletta, Fuad Samir Lopez Fernández, Marta, Mancheño, Blanca, Mateos-Serrano, Isabel Pascual Miguelañez, Maria Fernanda Pedrero Escalas, Julio, Peñarrocha, Yolanda, Perez, Maria Isabel Prieto-Nieto, Teresa Rivera Schmitz, Laura, Rodrigáñez, Ines, Rubio-Perez, Isabel Sanchez Cuadrado, José Ignacio Sánchez Méndez, Jorge Fernando Tone, Carlos Toribio Vazquez, Aitor, Urbieta, Diego Córdova García, Francisca Garcia-Moreno Nisa, Laura, Jiménez, Inmaculada, Lasa, Belen, Matías-García, Fernando, Mendoza-Moreno, Marina Pérez González, Ana Sánchez Gollarte, Alejandro Sanchez Pellejero, Cristina Vera Mansilla, Rafael, Barberá, Lourdes, Montes-Jovellar, Sara Fra Fernández, Nicolas Moreno Mata, Barbara, Algar-Yañez, Gutiérrez, Bérénice, Olga De La Varga-Martínez, Paula, Fernandez-Valdes-Bango, Sandra Maria Gadin-Lopez, José María Martínez-Gómiz, Elena, Nieto-Moreno, Ana, Nieto-Moreno, Montserrat Ocampos Hernandez, Maria Laura Pelegrina-Lopez, Alicia Ruiz Escobar, Elena, Sáez-Ruiz, Beatriz, Vazquez-Rivero, Antonio, Lara, Belén Vielva Del Campo, Fernando Alcaide Matas, Simbad, Costas-Ochoa, José María García Pérez, Elizabeth, Marmol, Paula Troncoso Pereira, Maria Del Pilar Concejo Cutoli, Juan Ramón Gómez López, Juan Carlos Martín Del Olmo, Paloma Guillamot Ruano, Javier Páramo Zunzunegui, Antonio Albarracín Marín Blázquez, Alfonso, Aliaga-Sanchez, Marta María Arroyo Domingo, Miriam Artés Artés, Ana Isabel Avellaneda Camarena, Aida, Blaya, Emny Rochell Bobadilla Romero, Pedro Vicente Fernández-Fernández, Lorena Galindo Iñiguez, Víctor Javier García Porcel, Clara Giménez Francés, Antonio Javier Gomez Poveda, Rebeca Gonzalez Celdran, Francisco Miguel González Valverde, Laura Guillamon Vivancos, Elena, Gurrea-Almela, Alejandra Jara Maquilón, Jose David Jimenez Parra, Abd Al Aziz Lanagrán Torres, Raquel Lax Perez, Carmen Maria Lopez Lopez, Francisco, Machado, Alfonso Marco Garrido, Florencio Manuel Marin Martinez, Victoria Martínez Muñoz, Esther, Medina, Olimpia, Molina, José Manuel Muñoz Camarena, Julian, Onate, Pedro Antonio Parra Baños, Emilio Peña Ros, Enrique, Rubio, Marina Sánchez Robles, Carlos Sanchez Rodriguez, María Valero Soriano, María Teresa Yepes García, Felipe, Alconchel, Andrés Balaguer Román, Valentín, Cayuela, Ana, Conesa, Ana Delegido García, Pedro José Gil Vázquez, Paula Gómez Valles, Francisco, Gómez-Bosch, Vicente, J León-Muñoz, Francisco, Martínez, Alvaro, Navarro-Barrios, Tatiana, Nicolás-López, Pablo Ramirez Romero, Emiliano, Cano-Trigueros, María Concepcion Alonso González, Leticia Gómez Viana, Ana Pastor Zapata, Elisa Contreras Saiz, Tamara Díaz Vico, Maria, Fernandez-Hevia, Luis Joaquín García Flórez, Raquel, Rodríguez-Uria, Sandra, Sanz, Lorena, Solar-Garcia, Aida Suárez Sánchez, Jaume, Gelonch, Dietmar, Reinaldo, Miriam Abdulkarim Polo, Asier, Aguirre, Marta Alomar Bofill, Santiago, Baena, Ashish, Bartakke, Carmen Cabeza Oliver, Marta Castro Suárez, José Andrés Cifuentes Rodenas, Olga Claramonte Bellmunt, Ant Onia Crespí Mir, Anabel De La Llave Serralvo, Mar, Escales, Isabel Rosa Fernández Burgos, Pablo Gandia Gonzalez, Juan Lliteras Jorge, María Cristina Martínez Canto, Javier, Mata, Andreu, Morell, Naila, Pagès, Sara Pérez Palao, Cristian Plaza Valiente, Catalina Ramon Barcelo, Carmen Reyero Fernández, Albert Reyes Claret, Leticia Rodriguez Vaquero, Maialen Saez de Vicuña Salinas, Pilar Santos Cidon, Concepcion, Segura, Aina, Serra, Maria Serra Guivernau, Maria Soler Pedrola, Marta, Tasende, Marta Torrent Lluch, María Inmaculada Valldeperas Hernández, Rosa-Maria, Yañez-Lpez, Andrea, Craus-Miguel, Laura Fernández Vega, Natalia Pujol Cano, Juan José Segura-Sampedro, Laura Colet Oliver, Ivan Dot Pascuet, Mireia, Duart, Isabel Tello Galindo, Eduardo Arrea Salto, Jaume Cámara Cabrera, Marta Camats Terré, Juan Gabriel Castro Ríos, Marta de la Rosa-Estadella, Anna, Fernandez-Colorado, Anna, Gasulla-Rodriguez, Antonio, Gimenez-Gaibar, Elena, Gonzalez, Yeray Maldonado Sotoca, Matilde, Molina-Corbacho, Montserrat Monfort Mira, Josep, Rodoreda, Marta Santos Espí, Arnau Verdaguer Figuerola, Elisa Angela Diego-Alonso, Jaime, López-Sánchez, Luis, Muñoz-Bellvis, Jacobo, Trebol, Borja, Aguinagalde, Cristina Gabriela Alzate Arsuaga, Ainhoa Andres Imaz, Iñigo, Arana, Coro Aranzabal Urrutia, Mikel, Armendariz, Lorena, Arrabal, Iñigo, Augusto, Adolfo, Beguiristain, Laura, Busto, Ainhoa, Cuevas, Itziar De Ariño, Alejandro, Elúa, Leticia, Fernandez, Arantza, Fernandez-Monge, Lander, Gallego, Alba, Garcia, Amaia Garcia Dominguez, Gregorio, Garmendia, Carmen, Grañén, Pelayo Hevia Rodríguez, Maria, Iraola, José Miguel Izquierdo, Aintzane, Lizarazu, Jon Ander Lizarbe, Claudia Cristina Lopes Moreira, Iker, López, Ruth Marquina González, Tania, Pastor, Adrián Recio Ayesa, Ana Paula Riverola Aso, Carballo, Rodríguez, Araceli, Rodrìguez, Maria Inmaculada Ruiz Montesinos, Patricia, Torres, Jose, Undabeitia, Ainara, Villafruela, Maria Barrionuevo Ramos, David, Blanco, Marta, Calderón, Eva Corral Rubio, Angel, Cuadrado-García, Daniela, Cubek, Ignacio, Fariña, Maria Fernandez LLorente, Natalia Flores Amador, Mariana García Virosta, Luis Garcia-Sancho Tellez, Adelina Gonzalez Martinez, María, Hernandez, Rubén Herreros Ruiz-Valdepeñas, Carmen Jimenez Sanchez, Eduardo Llamazares Cobo, María, López, Javier, López-Martin, Teresa Martínez Marivela, Luis Miguel Martinez Parra, Paloma Maté Mate, Paloma, Medrano, Manuel Moriche Carretero, Sara Núñez O'Sullivan, Manuel Ortega Oria de Rueda, María Begoña Pastor Nieto, Clara, Pérez, Antonio, L Picardo, Remedios Revilla Amores, Carmen Rodríguez Haro, Jose Alberto Rojo López, Fatima Sanchez Cabezudo Noguera, Cristina, Sanz, Daniel Serralta de Colsa, Cristina Valor Garcia, Marta Velasco Martinez, Iván Andújar Lara, Aranzazu, Calero-Lillo, Enrique, López-Ruiz, Alberto Díaz García, Alejandro Menéndez Moreno, Luis Eduardo Pérez-Sánchez, Ángela, Pascual, Miguel Adeba García, Marta Alonso Fernández, Javier Alvarez Gama, Roberto, Ballestero, Loreto Berjon De La Vega, Paola Calleja Hermosa, Mariana, Carrillo-Rivas, Alfonso, Casado, Andrea, Cerveró, Bonifacio Cimadevilla Calvo, Patricia Corriols Noval, Paloma de la Dehesa Cueto-Felgueroso, Miren Jasone Diez Zapirain, José Estevez Tesouro, José Antonio Fernández-Dívar Sánchez, Lucia Garcia Alcalde, Juan García Cardo, Tito García Moreno, Daniel, García-López, Belen Garcia-Montesinos Perea, Miren Gonzalez Benito, Rocio, Gonzalez-Aguado, Miguel Ángel Gordo Vega Gordo-Vega, Jose, Gutierrez-Banos, Jaime Jimeno Fraile, Yolanda Jubete Castañeda, Patricia Lopez Gomez, Antonia Jesús López López, David Mato Mañas, Carmelo, Morales-Angulo, Dieter, Morales-Garcia, Sara, Naranjo, Jose Luis Rabago, Jose Manuel Rabanal, Rocio Revuelta Zorrilla, Adriana Reyes Echeverría, Juan Carlos Rodríguez-Sanjuán, Juan Ramón Sanz, Isabel Simal Badiola, Guillermo, Tejón, Enrique Toledo Martínez, Raquel Varea Malo, Begoña, Fadrique, Tania, Funes, Elena González Revilla, Isaias, Alarcón, Daniel Aparicio Sánchez, Pablo Beltran Miranda, Carmen, Cepeda-Franco, María Josefa Cuevas López, Sandra, Dios-Barbeito, Virginia María Durán Muñoz-Cruzado, Carlos Gonzalez De Pedro, Rosa, M Jimenez-Rodriguez, Francisco, Manresa-Manresa, Gabriel, Marin, Cristobalina, Martin-Garcia, Sara, Martínez-Núñez, Juan Manuel Martos Martinez, Lucas, Mengíbar, Felipe Pareja Ciuro, Eduardo Perea Del Pozo, Veronica Pino Diaz, José, Pintor-Tortolero, Claudia, Quintero-Pérez, Maria Luisa Reyes Diaz, Mercedes Rubio Manzanares Dorado, Alejandro Sanchez Arteaga, Ana, Senent-Boza, Luis, Tallon-Aguilar, Jose, Tinoco-Gonzalez, Luis-Cristobal, Capitan-Morales, Juan Cintas Catena, Javier, Valdes-Hernandez, María Del Campo Lavilla, Alina López De Fernández, Miriam Abellan Lucas, Alba Diaz Padillo, Maria Gómez Romero, Linda Grace Puerto Tamayo, El Mostafa El Yaqine Er Raoudi, Melody García Domínguez, María Ángeles Gascón Domínguez, Marta González Pérez, Alba Hernáez Arzoz, Joana San Anton, Cristian, Ruminot, Hander Guillermo Acosta Diaz, Daniella, Laguado, Kristina, Aghababyan, Alba, Jr, Enrique, Artigues, Rocío, Belda, Miguel, Beltran, Jose Ignacio Blanes, Elena Campos Carot, Miriam, Cantos, Laura, Costa, Carolina Ferrer Gomez, José María Gallego Sánchez, Oscar, Gil-Albarova, Juan, Gilabert-Estellés, Emilio Lopez Alcina, Isabel López Sánchez, Severiano Marin Bertolin, Carolina, Martinez-Perez, Antonio Melero Abellán, Claudia Mulas Fernández, Beatriz, Novoa, Ruth, Nuñez, Pablo Renovell Ferrer, Guijarro-Jorge, Ricardo, Carolina Soledad Romero Garcia, Miguel Sanfeliu Giner, Silvia, M West, Enrique, Zapater, Ignacio, Miranda, Ana, Monís, Alejandro Roselló Añón, María José Sangüesa, Jorge Sanz Romera, Marcos, Adrianzén, Maria Barrios Carvajal, Mireia, Bauzá, Ana Benítez Riesco, Jose Antonio Carbonell Lopez, María-Carmen, Fernández-Moreno, Ricardo Gadea Mateo, Francisco, Garcia, Maris Luisa García-Pérez, Luisa Paola Garzon, Ana, Izquierdo, Maria Lapeña Rodríguez, Carlos, León-Espinoza, Fernando, Lopez, Rosa Martí Fernández, Sara Martínez Castro, Berta Monleón López, Isabel Mora Oliver, David, Moro-Valdezate, Ernesto Muñoz Sornosa, Sara Palomares Casasús, Leticia Pérez Santiago, Mara Albert Fort, Reyes, Balanzá, Lorena Bermell Marco, Carla Carratalá Pérez, Claudia Pilar Clemente Tomas, Marta, Córcoles, Jose Ángel Diez Ares, Carlos Domingo Del Pozo, Nuria Estellés Vidagany, Gonzalo, Garrigos, Mar Gimeno Gimeno Vicente, Blanca Alastrue Giner, Segundo, Gomez-Abril, Paloma, Gonzalez, Paula Gonzálvez Guardiola, Guillermo Sebastian Martínez Fernández, Charo Martínez García, Lucía, Martínez-Costa, Luz María Moratalla Charcos, Sergio Navarro Martínez, Carmen, Payá-Llorente, Álvaro Pérez Rubio, Nuria, Peris, Eduardo Picazo Pineda, Jordi Planelles Gómez, Francisco Ripoll Vidal, Andrea, Roca, Enrique, Salmerón-González, Raquel Segura Roselló, Ramon Trullenque Juan, Cristina Verdejo Gimeno, Jose Miguel Zaragozá García, Gema Zomeño Bravo, Marcos Bruna Esteban, Hanna, Cholewa, Milton de Jesus, Matteo, Frasson, Luis Oliver García, Héctor, J Aguado, Antonio Jose Alonso Villalba, Francisco, Ardura, Carmen Elena Badillo Bercebal, María Bedate Núnez, Alvarez-Ramos Begoña Aranzazu, Juan Beltrán de Heredia, Hugo, Bermejo, Juan Berrocal Cuadrado, Maria Bragado González, Juan, Bustamante-Munguira, Raul Calvo Gonzalez, Yolanda, Carrascal, Ana Belén Casas Marcos, María Carmen Cervera, Sergio Chávez Valladares, Ángel Cilleruelo Ramos, Susana, Cortes, Jesús, Crespo-Sanjuán, María, Cuaresma, Luis Antonio Cuellar Martin, Carlos Ferreras García, Alvaro, Fuentes-Martín, Abel, Ganso, Elena García García, Luis, Garcia-Florez, Virginia, Garcia-Virto, Juan, Gatón, Julio Alberto Gobernado Tejedor, Tania Gómez Sanz, Jose Ignacio González Martín, María Begoña Gregorio Crespo, Ana Herranz Arriero, Jose, Herreros, Marta Ibáñez Nieto, César, Infante, Carlos, Jezieniecki, Moises, Juarez, Gregorio de Jesus Labrador Hernandez, Ana Patricia Legido Morán, Ricardo León Fernández, Alejandro, Leon-Andrino, Almudena, Llorente, Maria Lopez Pais, Mauricio Loucel Bellino, Sergio, Martin, Miguel Angel Martin-Ferrero, Gonzalo Martinez Municio, Elvira Mateos Alvarez, José María Matilla, Luis María Merino Peñacoba, Mario, Montes-Manrique, Fernando Natal Álvarez, David, C Noriega, Henar Nuñez Del Barrio, Francisco Javier Ortiz de Solórzano Aurusa, Lucía, Pañeda, Victoria Pascual Escudero, Miguel Pascual Samaniego, Adela, Pereda, Marta Pérez Febles, Laura, Pesquera, Maria, Plata, Emma Puertas Ruiz, Mario, Rodriguez-Lopez, Alejandro Romero de Diego, Ana, Ruano, María Ruiz Soriano, Cristina Sánchez Torralvo, Silvia Santiago Maniega, Bárbara, Segura-Méndez, Clarisa Simon Perez, José, Soro-García, Paula Suárez Mansilla Suárez-Mansilla, Jeancarlos Trujillo Díaz, Mª Esther Valsero Herguedas, Andrea Vazquez Fernandez, Eduardo Velasco García, Ana, Zabalza, Álvaro Zamora Horcajada, Fernando Acebes García, Enrique Asensio Díaz, Martín, Bailón, Alejandro David Bueno Cañones, Alvaro Centeno Velasco, Ekta Choolani Bhojwani, Fernando Labarga Rodríguez, Sara, Mambrilla, Pablo, Marcos-Santos, Toledano, Miguel, David Pacheco Sánchez, Baltasar, Pérez-Saborido, Pilar, Pinto, Katherine, Plua, Javier Sanchez Gonzalez, Vicente, Simo, Rosalía Velasco López, Sandra Veleda Belanche, Fabiola Eugenia Michel Campos, Iciar Muñoz Lindez, Maria, Balluerca, Maite, Camuera, Pablo, Helguera, Imanol, Herrero, Patricia Paunero Vazquez, María, Sánchez-Rubio, Isami, Soeda, María Dolores Arribas Del Amo, Vicente Manuel Borrego Estella, Estefania, Casas, Néstor Castán Villanueva, Daniel Delfau Lafuente, Elena Delgado Blanco, María, Domingo, Ismael Gil Romea, Azucena, Gonzalo, Emilio Lagunas Lostao, Noelia Lete Aguirre, Yaiza Martinez Lahoz, Jesús Víctor Pérez-Tierra Ruiz, Maria Del Mar Soriano, Isabel Valero Lázaro, Esmeralda Carnicer Escusol, Guillermo Pola Bandres, Juan Luis Blas Laina, Beatriz, Cros, Patricio Andrés Freile Pazmiño, David, Garcia-Aguilera, Ana Mejía Casado, Ana, Nogués, Issa Talal El-Abur, Carlos, Yánez, Isabel Gascon Ferrer, Carlos, Gracia-Roche, Ursula María Jariod Ferrer, María Victoria Simón Sanz, Tomas, Uson, Waseem, Ahamed, Sumudu, Jayasinghe, Eranda, Karunadasa, Prathibha, Nelihela, Sujeewa Priyantha Bandara Thalgaspitiya, Dickson, Wickramarathna, Nagenthiram, Harivallavan, Pirashanthan, Nagarasa, Eranga, Perera, Kanapathipillai, Piratheep, Vithranage Srimantha Dewsiri Rodrigo, Meera, Thayalan, Rajendram, Thayaparren, Arulprashanth, Arulanantham, Kanishka De Silva, Gagana, Ganga, Anuja Nadeeshan Kumarasinghe, Mahanada, Udukala, Koculen, Vimaleswaran, Prashanthan, Yogarajah, Ravindri, Jayasinghe, Probhodana, Ranaweera, Mohamed, Rishard, Dharmabandhu, N Samarasekera, Sanjeewa, Seneviratne, Sivasuriya, Sivaganesh, Chamal, Fernando, Nishantha, Mendis, Balasingam, Balagobi, Balasupramaniam, Sathesan, Lanka, Dasanayake, Malitha, Patabendige, Wickramasooriya, Dj, Kugarajh, Ganeshapillai, Sathyamoorthy, Prasanna, Dileepa, Ediriweera, Sumudu, Kumarage, Asanka, Jayawardane, Athula, Kaluarachchi, Pituwala Liyanage Adithya Sirisena, Abubakr, Abubakr, Hozifa, Mohamed, Ismail, Mustafa, Mogahid, Sharfeldein, Samir, Ismail, Reem, Musa, Monira, Sarih, Mussab, Abaker, Eman Adam Abdalla, Mohamad, Abdelbagi, Alsafe, Adlan, Ahmed, Alnaeem, Safa, Atyah, Yasir, Awad, Rsheeda, Dawelbait, Mohamed El Hag, Ibrahim, Elbashir, Sami, Eldirdiri, Samwal, Eldirdiri, Mohammed Eltahier Abdalla Omer, Lana Abdalgadir Ahmed Mohamed, Hiba Hassan Rehmtallah Ahmed, Mohammed Balla Yousif Balla, Abdulmoiz, Aljafari, Abdulmalek, Aljafari, Elsagad, Mohamed, Abdulkader, Mohammad, Abdulkader, Shaar, Mohamed Nafea Shaar, Maab Hussein Yousif Elhafiz, Mohammed Husien Yosif Elhafiz, Abubakr Ali Mohammed Alhassan Humidan, Almigdad, Ali, Hisham, Eljack, Mohamedyasin, Elrashid, Manhal, Ahmed, Albrra, Alhag, Douaa, Ali, Mohammed Ahmed Babikir, Imad, Bakheit, Hytham K, S Hamid, Sami, Mohamed, Walid, Shaban, Nidhal, Siddig, Mohamed, Suliman, Rihab Yasir Abdelmagid, Abubaker, Yassin, Omer, Abbas, Eltahir, Abdelrahim, Muhammed, Ahmed, Mohamed, Elobaid, Adil, Hashim, Ali, Mohamed, Omer, Mohamed, Khalid, Osman, Abdallah, Yousif, Safaa, Abdulaal, Marwa, Elsadig, Mohammed, Hussain, Malaz Amir Ataalmanan, Doha Amir AtaAlmanan, Tebyan Amir AtaAlmanan, Alaa, Elgaili, Maria, Mohamed, Usra, Omara, Alkhansa, Osman, Amna, Osman, Safaa, Saad, Abdelkareem, Ahmed, Ali Adil Ali Karar, Aya, Alhassan, Mohanad, Alsidig, Mohamed, Eljack, Mohammed Ibrahim Mohammed Ali, Awad Kamal Awad Osman, Liena, Mohamed, Samah Ibrahim Omer Mohamed Osman Mohamed Osman, Altayeb, Mohammed, Ayman, Mohammed, Khadija, Muhmmed, Eltahir, Musa, Egbal Sahal Abdelmajed, Khalid Z M, Y Hamid, Omnia M, M Yousif, Mahmoud, Saleh, Osman, Bashir, Yassein, Elhussein, Omar, Madani, Eva, Angenete, Jennifer, Park, Lars, Gillberg, Monir, Jawad, Linas, Pieteris, Yousif, Saeed, Sergej, Safonov, Martin, Spångfors, Henrik, Andersson, Hans, Bahlmann, Karin Björnström Karlsson, Michelle, Chew, Lara, Daham, Lina De Geer, Helen, Didriksson, Gunilla, Gagnö, Carina, Jonsson, Anna, Oscarsson, Pamela, Buchwald, Mathilde, Delorme, Marie-Louise, Lydrup, Shahin, Mohseni, Arvid, Pourlotfi, Souheil, Reda, Kajsa, Anderin, Nina, Blomme, Josefin, Segelman, Malin, Simlund, Anders, Thorell, Fredrik, Wogensen, Daniel, Danielsson, Peter, Elbe, Rebecka, Hultgren, Boel, Hynning, Fredrik, Klevebro, Karin, Lind, Ebba, K Lindqvist, Carl, Montan, Ernesto, Sparrelid, Clara Svenberg Lind, Jeremy, Wales, Andreas, Älgå, Martin, Nordberg, Emil, Pieniowski, Ioannis, Gkekas, Niklas, Löfgren, Karolina, Niska, Robert, Zürner, Silvio, Däster, Otto, Kollmar, Savas, Soysal, Stephanie, Taha-Mehlitz, Athanasios, Tampakis, Dominik Valentin Flury, Marie, Heyne-Pietschmann, Gregor Jan Kocher, Ana, M Calinescu, Barbara, Wildhaber, Markus, Gass, Jürg, Metzger, Andreas, Scheiwiller, Lukas, Briner, Oliver, Dwidar, Steven, Grandjean, Pietro, Ricciardi, Alexandra, Calmels, Christodoulou, Michel, Morena, Antonilli, Dimitrios, Christoforidis, Alessandra, Cristaudi, Jacopo, Galafassi, Maria Luisa Gasparri, Francesco, Mongelli, Martino, Munini, Andrea, Papadia, Sotirios Georgios Popeskou, Alex, Alfieri, Thomas, Bächler, Matteo, Giardini, Christian, Gingert, Laura, Guglielmetti, Inna, Meyer, Tobias, Müller, Daniel, Schöni, Folco, Solimene, Frank, Weidner, Marco, Bueter, Daniel, Gero, Amelie, Müller, Carmen, Portenkirchner, Andreas, Thalheimer, Jeannette, Widmer, Ahmad, Hmaideh, Alaa, Kour, Saleem, Swaes, Omar, Alannaz, Ramez, Aljasem, Ezeddin, Dabbagh, M Wafa Hamoud Alhussein, Amr, Hamza, Mazen, Mohammad, Abd El-Fattah Mouhandes, Mohamad, Shareeda, Mohammad Nour Shashaa, Mousa, Sifat, Sheraa, Tahhan, Rahaf, Toutounji, Mohamed, Abdulrahman, Albaraa, Abdulsalam, Ziad Al Jarad, Hala, Alayyoubi, Dina, Alfarra, Ahmad, Alhamid, Mahmoud, Alnasser, Mulham, Gharib, Ruwaid, Gharib, Obaida, Kabel, Osama, Kherallah, Abdulqader, Klaho, Mohamed Shukri Najjar, Ahmad, Razouk, Joud, Shiekhoni, Wael, Alkhaleel, Amira, Almosa, Mohammad, Aloulou, Maen, Alzaeem, Khaled, Arnaout, Muhamad Zakaria Brimo Alsaman, Mohamad, Estanbouli, Hanadi, Hawa, Ahmad Nbrass Kabawi, Ghina, Maarawi, Yehia, Mashhadany, Sana Shaikh Torab, Waleed, Abd, Tayma Abd Alghafour, Hani, Abdalnour, Nazeeh Al Aktaa, Marwan Al Aliwy, M Maher Al Arje, Tasneem Al Najjar, Ahmad, Al-Mouakeh, Ahmad, Aldakhil, Aos, Alhamid, Hasan, Alhasan, Mohamad Shadi Alkarrash, Jumaa, Alkhamis, Sara, Alshekh, Ahmad Yamen Arnaout, Oula, Azizeh, Mohammed, Dalaleh, Aghyad, Danial, Zain, Douba, Raghad, Ghadri, Mohammad Maen Ghannam, Anas, Ghawi, Luma Haj Kassem, M Yasser Halwani, Shahed, Hamadieh, Mohammad, Hanino, Ala Aldeen Hasan, Haya, Jawish, Nasr Ullah Kabbani, Saadullah, Kabbany, Mohamad, Kadi, Lama, Kadoura, Ahmad Amir Kayali, Ammar, Kayyali, Aya, Kelzia, Amana, Kezze, Abdullah, Khalaf, Maymona, Khayata, Mohammad Nour Kitaz, Mohammad, Kour, Raghad, Makki, Ruqaya, Masri, Joseph, Masri, Noor, Masri, Muhammad, Mazketly, Shiar, Mustafa, Ezzeldin, Nashed, Yaman Qoudra Danial, Hasan, Raslan, Rima, Salem, Mohammed Asaad Salem, Thabet Sayed Bakir, Manaf, Sharabaji, Majd Sheikh Alganameh, Duaa Sheikh Kadro, Joudy, Shurbatji, Mohammad Noor Sultan, Dana, Sultan, Hala, Swied, Bakri Tarras Jarkas, Tayf, Toutounji, Fadi, Ward, Rama, Zazo, Aya, Zazo, Zainab, Zeino, Mohamed, Alaktaa, Wael, Alsado, Hala, Fares, Nouran, Hawa, Hamza, Ibrahim, Abdulmonem, Kawas, Mourad, Niazi, Bayan, Toutounji, Mohammad, Abdow, Mohamad, Ahmad, Tareq, Ahmad, Rawan Al Azhar, Hiba Al Hage Diab, Rahaf Al Mulke, Mohammad, Al-Jadaan, Ahmad, Alhussein, Zahra, Alnajem, Omar, Alneser, Bayan, Alsaid, Elias, Azar, Lubna, Bakr, Ammar, Hamza, Yara, Houdifa, Sami, Jomaa, Samer, Kefo, Hiba, Mardini, Alaa, Mohammad, Fadi, Rayya, Fatima, Razzouk, Mohannad, Saleh, Anwar, Shamandi, Ammar Youzkatli Alkhatib, Omar Abdul Salam, Dany, Ajami, Mohammad, Alhamid, Ahmad, Alkhaledi, Danny, Hadidi, Massa, Jabra, Mamdouh, Kallas, Antoine, Laktine, Joelle, Naem, Naya, Naoum, Ghena Mohammed Fawaz Ashour, Ahmad, Alhouri, Deema, Fallouh, Ahmad, N Mohammad, Ahmad, Rmman, Ali, Slitin, Christine, Tanos, Ibrahim, Wakim, Hanaa, Zahrawi, Majd, Abouassi, Layth, Abouassi, Ayham, Aboutrab, Basel, Ahmad, Ahmad Mustafa Ahmad, Aya, Ahmad, Afaf, Ahmad, Mohamad, Alabras, Mohammad, Albasheer, Ola, Alkasser, Mhd Khaled Alkasser, Ali, Alkhdor, Marah, Azkoul, Mohammad Karam Chaaban, Haya, Deeb, Basel, Jazieh, Basel, Kouz, Youssef, Kozah, Raied, Mohamad, Ammar, Mohammad, Mhd Zied Nasri, Mohammed Mouaz Shebani, Mohammed, Shwin, Alaa, Sommaq, Amal, Youssef, Tala Al Asadi, Suhad, Alkhateb, Rasha Khalil Alsayyad, Roula, Altom, Mhd Amin Alzabibi, Batoul, Bakkar, Hlma, Ismail, Salma Khadem Alsrouji, Sara, Melhem, Mohamad, Sankari, Mosa, Shibani, Noura, Shujaa, Ibrahim, 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Giuseppe Salamone, Francesca Toia, Massimiliano Tripoli, Nepogodiev, D, Rosati, R, Surgery, Medicine and Pharmacy academic/administration, Basic (bio-) Medical Sciences, Surgical clinical sciences, Faculty of Medicine and Pharmacy, Gastroenterology, Medical Oncology, Clinical sciences, Breda, João, ARD - Amsterdam Reproduction and Development, Paediatric Surgery, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, AGEM - Endocrinology, metabolism and nutrition, Graduate School, Tytgat Institute for Liver and Intestinal Research, Laura Alberici, Filippo Antonacci, Alessandro Arena, Angela Belvedere, Fabio Bernagozzi, Paolo Bernante, Pietro Bertoglio, Lorenzo Bianchi, Maria Bisulli, Barbara Bonfanti, Safia Boussedra, Jury Brandolini, Crescenzo Cacciapuoti, Stefano Cardelli, Riccardo Casadei, Matteo Cescon, Alessandro Cipolli, Riccardo Cipriani, Alfredo Conti, Luca Contu, Francesco Costa, Niccolo’ Daddi, Eugenia De Crescenzo, Pierandrea De Iaco, Alessandra De Palma, Massimo Del Gaudio, Anna Nunzia Della Gatta, Giampiero Dolci, Giulia Dondi, Matteo Droghetti, Sergio Nicola Forti Parri, Elena Garelli, Chiara Gelati, Giuliana Germinario, Federico A. Giorgini, Carlo Ingaldi, Elio Jovine, Kenji Kawamukai, Antonio Lanci Lanci, Raffaele Lombardi, Maria Elisa Lozano Miralles, Claudio Marchetti, Michele Masetti, Francesco Minni, Daniele Morezzi, Daniele Parlanti, Alice Pellegrini, Anna Myriam Perrone, Anna paola Pezzuto, Marco Pignatti, Gianluigi Pilu, Valentina Pinto, Gilberto Poggioli, Silvana Bernadetta Puglisi, Diego Raimondo, Matteo Ravaioli, Claudio Ricci, Sara Ricciardi, Francesco Ricotta, Roberta Rizzo, Angela Romano, Matteo Rottoli, Riccardo Schiavina, Renato Seracchioli, Matteo Serenari, Margherita Serra, Piergiorgio Solli, Gioia Sorbi, Mario Taffurelli, Marta Tanzanu, Achille Tarsitano, Marco Tesei, Gabriele Vago, Tommaso Violante, Simone Zanotti, Tommaso Frisoni, leonardo solaini, giorgio ercolani, Fruscio, R, Ornaghi, S, Collaborative, Covidsurg, Collaborative, Globalsurg, Palmisano, Silvia, de Manzini, Nicolo', Žundienė, Laura, Dulskas, Audrius, Kuliavas, Justas, Čekauskas, Albertas, Kielaitė-Gulla, Aistė, Poškus, Tomas, Strupas, Kęstutis, Želvys, Arūnas, COVIDSurg Collaborative, GlobalSurg Collaborative, Department of Surgery, HUS Abdominal Center, Simoes, Jff, Li, E, Picciochi, M, Glasbey, Jc, Baiocchi, G, Blanco-Colino, R, Chaudhry, D, Alameer, E, El-Boghdadly, K, Wuraola, F, Ghosh, D, Gujjuri, Rr, Harrison, Em, Lule, H, Kaafarani, H, Khosravi, M, Kronberger, I, Leventoglu, S, Mann, H, Mclean, Ka, Mengistu, Gm, Modolo, Mm, Ntirenganya, F, Norman, L, Outani, O, Pius, R, Pockney, P, Qureshi, Au, Roslani, Ac, Satoi, S, Shaw, C, Bhangu, A, Omar, Om, Ahmed, Wur, Argus, L, Ball, A, Bywater, Ep, Brar, A, Dawson, Be, Duran, I, Elhadi, M, Jones, C, Kamarajah, Sk, Keatley, Jm, Lawday, S, Marson, Ej, Ots, R, Santos, I, Taylor, Eh, Trout, Im, Varghese, C, Venn, Ml, Xu, W, Dajti, I, Gjata, A, Kacimi, Seo, Boccalatte, L, Cox, D, Townend, P, Aigner, F, Kronberger, Ie, Samadov, E, Alderazi, A, Hossain, K, Padmore, G, van Ramshorst, G, Lawani, I, Cerovac, A, Delibegovic, S, Gomes, Gma, Buarque, Il, Gohar, M, Slavchev, M, Nwegbu, C, Agarwal, A, Martin, J, Ng-Kamstra, J, Olivos, M, Lou, Wh, Ren, Dl, Calvache, Ja, Rivera, Cjp, Hadzibegovic, Ad, Kopjar, T, Mihanovic, J, Jimenez, Pma, Gouvas, N, Klat, J, Novysedlak, R, Amisi, N, Christensen, P, El-Hussuna, A, Batista, S, Lincango-Naranjo, E, Emile, S, Sandoval, Daa, Dhufera, H, Hailu, S, Mengesha, Mg, Kauppila, Jh, Arnaud, Ap, Demetrashvili, Z, Albertsmeier, M, Lederhuber, H, Loffler, Mw, Acquah, Dk, Ofori, B, Tabiri, S, Metallidis, S, Tsoulfas, G, Aguilera-Arevalo, Ml, Recinos, G, Mersich, T, Wettstein, D, Kembuan, G, Milan, Pb, Khosravi, Mh, Mozafari, M, Hilmi, A, Mohan, H, Zmora, O, Gallo, G, Pata, F, Pellino, G, Fujimoto, Y, Kuroda, N, Abou Chaar, Mk, Ayasra, F, Fakhradiyev, I, Hamdun, Ih, Jin-Young, J, Jamal, M, Karout, L, Gulla, A, Rasoaherinomenjanahary, F, Samison, Lh, Sanchez, Iid, Gonzalez, D, Martinez, L, Martinez, Mj, Nayen, A, and Ramos-De la Medina, A

Subjects
Male, Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], MULTICENTER, infectious diseases, 0302 clinical medicine, 030202 anesthesiology, Anesthesiology, Cirugía, 80 and over, Prospective Studies, Young adult, Child, Lung, Aged, 80 and over, COVID-19, delay, SARS-CoV-2, surgery, timing, SARS‐CoV‐2 infection, Operative, Child, Preschool, Pneumonia & Influenza, Infection, Cohort study, Human, medicine.medical_specialty, Clinical Sciences, Sars-cov-2, GlobalSurg Collaborative, Settore MED/28 - MALATTIE ODONTOSTOMATOLOGICHE, 03 medical and health sciences, Clinical Research, Biodefense, Correspondence, Humans, PULMONARY COMPLICATIONS, CRIANÇAS EM IDADE PRÉ-ESCOLAR, Aged, Science & Technology, Cirurgia, Prevention, Infant, Odds ratio, Pneumonia, Prospective Studie, Clinical research, Surgery, Human medicine, 610 Medizin und Gesundheit, 1109 Neurosciences, Internationality, Settore MED/29 - CHIRURGIA MAXILLOFACCIALE, Settore MED/18 - CHIRURGIA GENERALE, Adolescent, Adult, Cohort Studies, Female, Middle Aged, Surgical Procedures, Operative, Time, Young Adult, Practice Guidelines as Topic, gastroenterology, Medicine and Health Sciences, 030212 general & internal medicine, Prospective cohort study, Mortality rate, Covid19, Infectious Diseases, Patient Safety, medicine.symptom, 6.4 Surgery, Life Sciences & Biomedicine, 610 Medicine & health, COVID-19, SARS-CoV-2, delay, surgery, timing, Asymptomatic, NO, COVIDSurg Collaborative, Vaccine Related, All institutes and research themes of the Radboud University Medical Center, medicine, Mortalitat, ddc:610, Mortality, Preschool, LS7_4, Surgical Procedures, business.industry, Neurosciences, Evaluation of treatments and therapeutic interventions, 1103 Clinical Sciences, 3126 Surgery, anesthesiology, intensive care, radiology, Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10], Anesthesiology and Pain Medicine, Emerging Infectious Diseases, Good Health and Well Being, Mortalidad, Cohort Studie, business
Abstract

Peri-operative SARS-CoV-2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS-CoV-2 infection. This international, multicentre, prospective cohort study included patients undergoing elective or emergency surgery during October 2020. Surgical patients with pre-operative SARS-CoV-2 infection were compared with those without previous SARS-CoV-2 infection. The primary outcome measure was 30-day postoperative mortality. Logistic regression models were used to calculate adjusted 30-day mortality rates stratified by time from diagnosis of SARS-CoV-2 infection to surgery. Among 140,231 patients (116 countries), 3127 patients (2.2%) had a pre-operative SARS-CoV-2 diagnosis. Adjusted 30-day mortality in patients without SARS-CoV-2 infection was 1.5% (95%CI 1.4-1.5). In patients with a pre-operative SARS-CoV-2 diagnosis, mortality was increased in patients having surgery within 0-2 weeks, 3-4 weeks and 5-6 weeks of the diagnosis (odds ratio (95%CI) 4.1 (3.3-4.8), 3.9 (2.6-5.1) and 3.6 (2.0-5.2), respectively). Surgery performed ≥ 7 weeks after SARS-CoV-2 diagnosis was associated with a similar mortality risk to baseline (odds ratio (95%CI) 1.5 (0.9-2.1)). After a ≥ 7 week delay in undertaking surgery following SARS-CoV-2 infection, patients with ongoing symptoms had a higher mortality than patients whose symptoms had resolved or who had been asymptomatic (6.0% (95%CI 3.2-8.7) vs. 2.4% (95%CI 1.4-3.4) vs. 1.3% (95%CI 0.6-2.0), respectively). Where possible, surgery should be delayed for at least 7 weeks following SARS-CoV-2 infection. Patients with ongoing symptoms ≥ 7 weeks from diagnosis may benefit from further delay. ispartof: ANAESTHESIA vol:76 issue:6 pages:748-758 ispartof: location:England status: published

Published
2021

42. LRRC8A-containing chloride channel is crucial for cell volume recovery and survival under hypertonic conditions

Author

Miguel A. Valverde, René Böttcher, Selma A. Serra, Pablo Latorre, David Canadell, Jason Moffat, Francesc Posas, Predrag Stojakovic, Eulàlia de Nadal, Michael Aregger, Fanny Rubio-Moscardo, Ramon Amat, and Gerhard Seisenbacher

Subjects
Osmotic shock, Cell Survival, p38 mitogen-activated protein kinases, Ribosomal Protein S6 Kinases, 90-kDa, Osmostress, NKCC, Chloride Channels, Osmotic Pressure, Humans, Phosphorylation, Protein kinase A, Tissue homeostasis, Cell Size, Multidisciplinary, Cell Death, Kinase, Chemistry, Sodium, Membrane Proteins, Biological Transport, LRRC8A chloride channel, Cell biology, p38/MSK1, Hypertonic Stress, Chloride channel, Potassium, Commentary, RVI, CRISPR-Cas Systems, Cotransporter, HeLa Cells
Abstract

Regulation of cell volume is essential for tissue homeostasis and cell viability. In response to hypertonic stress, cells need rapid electrolyte influx to compensate water loss and to prevent cell death in a process known as regulatory volume increase (RVI). However, the molecular component able to trigger such a process was unknown to date. Using a genome-wide CRISPR/Cas9 screen, we identified LRRC8A, which encodes a chloride channel subunit, as the gene most associated with cell survival under hypertonic conditions. Hypertonicity activates the p38 stress-activated protein kinase pathway and its downstream MSK1 kinase, which phosphorylates and activates LRRC8A. LRRC8A-mediated Cl- efflux facilitates activation of the with-no-lysine (WNK) kinase pathway, which in turn, promotes electrolyte influx via Na+/K+/2Cl- cotransporter (NKCC) and RVI under hypertonic stress. LRRC8A-S217A mutation impairs channel activation by MSK1, resulting in reduced RVI and cell survival. In summary, LRRC8A is key to bidirectional osmotic stress responses and cell survival under hypertonic conditions. This work was supported by grants from the Ministry of Science, Innovation, and Universities (PGC2018-094136-B-I00 to F.P.; BFU2017-85152-P and Fondo Europeo de Desarrollo Regional [FEDER] to E.d.N.; RTI2018-099718-B-I00 and FEDER to M.A.V.), the Catalan Government (2017 SGR 799), the Fundación Botín, and the Banco Santander through its Santander Universities Global Division to F.P. We gratefully acknowledge institutional funding from the Ministry of Science, Innovation and Universities through the Centres of Excellence Severo Ochoa Award and from the Centres de Recerca de Catalunya (CERCA) Programme of the Catalan Government and the Unidad de Excelencia María de Maeztu, funded by the Agencia Estatal de Investigación (AEI) (CEX2018-000792-M). F.P. and E.d.N. are recipients of an Institució Catalana de Recerca i Estudis Avançats (ICREA) Acadèmia award (Generalitat de Catalunya).

Published
2021

43. Hernia del espacio de Petersen en paciente intervenido de bypass gástrico

Author

Pedro López-Morales, Antonio Albarracín-Marín-Blázquez, and Francisco Miguel González-Valverde

Subjects
Internal hernia, Male, medicine.medical_specialty, Hernia, medicine.diagnostic_test, business.industry, education, Laparoscopic gastric bypass, Gastric Bypass, Exploratory laparoscopy, Computed tomography, medicine.disease, digestive system diseases, Surgery, Hernia, Abdominal, Obesity, Morbid, Internal Hernia, Medicine, Humans, Laparoscopy, Mesentery, business, Retrospective Studies
Abstract

Petersen's space hernia is the most frequent location of internal hernia after a laparoscopic gastric bypass. The diagnosis or a high suspicion of internal herniation are indications for urgent surgery. We present the case of a patient who required an exploratory laparoscopy. He had a computed tomography compatible with internal herniation. We found a Petersen's space hernia and a jejunojenustomy defect. We reduced the protruded loops and we closed both mesenteric defects. The closure of mesenteric defects in primary surgery is a controversial matter. Overall, it is recommended to close them.Las hernias del espacio de Petersen son la localización más frecuente de las hernias internas tras un bypass gástrico laparoscópico. Su diagnóstico, e incluso su sospecha, son indicación de cirugía urgente. Presentamos el caso de un paciente que requirió una laparotomía exploradora en la que se halló una hernia del espacio de Petersen tras presentar en la tomografía computarizada el signo del «remolino». Se realizó la reducción de las asas intestinales herniadas junto al cierre del defecto mesentérico de dicho espacio. El cierre de los defectos mesentéricos en la cirugía primaria continúa generando controversia, pero como norma general se recomienda su cierre.

Published
2020

44. Umbilical incisional hernias (M3): are trocar-site hernias different? Comparative analysis of the EVEREG registry⋆

Author

Ana Ciscar Belles, Touria Makhoukhi, Manuel López-Cano, Pilar Hernández Granados, José Antonio Pereira Rodríguez, Antonio Utrera González, José M. Capitán Vallvey, Matías Pradas, Daniel Pérez Gomar, Manuel Bustos, Francisco Antonio Herrera Fernández, Juan A. Blanco, Joaquim Robres Puig, Rafael Villalobos, Dolors Güell Puigcercos, José María Puigcercós Fusté, Vicente Ayuso Osuna, Marta Piñol, Carles Olona Casas, Francisco Martínez Ródenas, Jordi Comajuncosas, Enric Sebastián Valverde, Sara Amador, Jaume Gelonch, Helena Vallverdú, Magda Abelló Sala, Antonio Veres Gómez, Rosa Gamón, Pedro García Peche, Miguel González Valverde, Miguel Ángel Martín Blanco, Ramón J Ferri, Elena Martí Ciñat, Providencia García Pastor, Carlos Montero, Miguel Ángel Lorenzo Liñán, Vicente Barbero, Miguel Ángel Morlan, José María Jover, Isabel Delgado Lillo, María Mercedes Sanz Sánchez, Leire Zarain Obrador, Alejandro Lusilla, Juan Jesús Cabeza Gómez, Antonio López, Teresa Butrón, Guillermo Supelano Eslait, José Luis Álvarez Conde, Baltasar Pérez Saborido, Mario Rodríguez López, Santiago Revuelta Álvarez, Pedro Trillo Parejo, José Luis Rodicio, Antonio Blanco, Agustín Juan Cano Maldonado, Ángel Zorraquino González, Esther Guisasola, Fernando Fernández, Javier Granell, Juan Antonio Bellido Luque, Juan Manuel Rueda Pérez, Mª Pilar Anaya Reig, Rafael Gómez Sabater, Rosa Ana García Díaz, and Verónica Alonso

Subjects
Cross-Sectional Studies, Postoperative Complications, Recurrence, General Engineering, Humans, Incisional Hernia, Surgical Instruments, Hernia, Umbilical
Abstract

Incisional hernia (HI), in open and laparoscopic surgery, is a very frequent complication. HI located in the umbilical region are called M3. The main aim of this study is to compare HI produced by the placement of an umbilical laparoscopic trocar (M3T) with those located in M3 in open surgery (M3O) in terms of basal characteristics, complications and recurrences; and secondarily the identification of risk factors.Cross-sectional observational study based on the national prospective registry EVEREG during the period of July 2012-June 2018. The main variables were recurrences and postoperative complications. Both groups (M3T and M3O) were compared. Multiple logistic regression was performed to identify the risk factors of the entire cohort.882 had a follow-up time longer than 12 months. M3O group presented superior ASA-Class, more complex HI and previous repair. It also presented a higher recurrence rate at 12 and 24 months (8.6% vs. 2.5%; P0,0001 and 9.3% vs. 2.9%; P0.0001) and higher postoperative complications rate (21.9% vs. 14.6 %; P = 0.02). Previous repair, intervention length and associated procedures requirement were identified as risk factors for postoperative complications. Absence of a specialist present during surgery, previous repair, and the absence of complications were identified as risk factors for recurrence. In the PSM analysis no differences were detected in of complications and recurrences.HI M3O is more complex than M3T. The complexity is not related to the origin of the hernia but to its characteristics and those of the patient.

Published
2020

45. Biocompatible POSS-gold nanocomposites synthesized by laser ablation in ethanol

Author

M.B. de la Mora, Miguel A. Valverde-Alva, R. Castañeda-Guzmán, T. García-Fernández, C. Sánchez-Aké, Jean Y. Tovar-Sánchez, René García-Contreras, and Mayo Villagrán-Muniz

Subjects
chemistry.chemical_classification, Materials science, Nanocomposite, Laser ablation, Biocompatibility, technology, industry, and agriculture, Nanoparticle, Polymer, Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials, Absorbance, Colloid, Chemical engineering, chemistry, Colloidal gold, Electrical and Electronic Engineering
Abstract

Polymer-gold nanoparticle nanocomposites based on POSS polymer with a thiol group was obtained by laser ablation in liquids (LAL). Laser ablation of a gold target in a solution of ethanol and POSS-thiol produced high purity nanocomposites of POSS decorated with gold nanoparticles (Au NPs) in colloidal suspension. TEM characterization showed spherical geometry of the Au NPs, mainly smaller than 60 nm. The UV–Vis-NIR spectroscopy exhibited the typical absorbance spectra for spherical Au NPs in the visible range (520–550 nm) related to plasmonic behavior. POSS-Au NPs nanocomposites exhibited an improvement in the colloid stability, absorbance peak and reproducibility, compared to the NPs without POSS-thiol. The optimal values were found for Au NPs synthesized in a POSS-thiol ethanol solution at 0.0168 mM. The low cytotoxic activity in human gingival fibroblasts (HGF) suggest the biocompatibility of the nanocomposite. The optical properties and biocompatibility of the nanocomposite shows its use viability for applications as biosensors based in optical response.

Published
2022

46. Mesospheric/Thermospheric temperatures and high altitude water on Mars in the MY34

Author

Oleg Korablev, Miguel Lopez-Valverde, Juan Alday, Franck Lefèvre, Franck Montmessin, Andrey Patrakeev, Denis Belyaev, Anna Fedorova, and Alexander Trokhimovskiy

Subjects
Water on Mars, Environmental science, Effects of high altitude on humans, Atmospheric sciences
Abstract

Introduction The southern spring and summer on Mars in the 34th Martian Year (MY34, Ls 180o-360o) was decorated by two dust storms: the global one (GDS) at Ls 190o-240o, and the regional one at Ls 320o-330o. Just before the onset of the GDS, the nominal ExoMars Trace Gas Orbiter mission began (April 2018) with an onboard solar occultation experiment by the spectrometric Atmospheric Chemistry Suite (ACS) [1]. The first ACS-NIR retrievals of the temperature and water mixing ratio revealed an increase the H2O abundance up to altitudes of 80-100 km not only in the stormy events but also at the perihelion in the southern hemisphere (around Ls~270o) [2]. Moreover, as it was shown, the water supersaturation occurs even in presence of the ice clouds, while the stormy warm atmosphere rises the hygropause level [2, 3]. This phenomenon increases a capability of water escape from Mars. Simultaneous investigation from the NOMAD/TGO solar occultations demonstrated analogue results for the H2O enhancement up to 80 km in the stormy seasons, but without the saturation estimations [4]. In this paper, we present results from more sensitive solar occultation measurements in the 2.65-2.7 μm spectral range by the middle infrared channel of ACS (ACS-MIR). The channel allows mesospheric and thermospheric retrievals of temperature and CO2 density in parallel with the mesospheric water abundance. Our results confirm the ACS-NIR and NOMAD conclusions concerning the H2O vapour behaviour in the second half of the MY34. We report the most humid mesosphere occurred in the perihelion season where the water enrichment was established about 5-10 ppbv at altitudes of 110-120 km. We also present the temperature and CO2 density seasonal distribution covering the troposphere, the mesosphere and the thermosphere of Mars. Measurements The ACS-MIR channel is a cross-dispersion echelle spectrometer dedicated to solar occultation measurements in the 2.3–4.3 μm wavelength range [1]. The instrumental resolving power λ/Δλ reaches ~30 000, while the altitude resolution is 1-2 km and the signal/noise ratio is about ~1000. Each occultation session covers a spectral interval with one or a few CO2 absorption bands appropriate for the atmospheric density and temperature retrievals. In this work, we perform data analysis in the 2.65-2.7 μm spectral range, which occupies echelle diffraction orders from 221 to 224, observed simultaneously. This spectral region hosts strong CO2 and H2O absorption bands that are sensitive to detections of CO2 density up to 180-190 km and H2O density up to 120-130 km. For the MY34 the MIR dataset in the considered spectral range is made of ~100 occultation profiles in the Northern hemisphere and of ~90 in the Southern one encompassing seasonal period from Ls 165o to 355o. Retrieval concept The temperature and densities retrieval scheme consists of several iterations with a fitting of a forwardly modelled transmission spectrum to a measured one at each observed altitude. The model includes line-by-line calculations CO2 and H2O absorption cross sections depending on specified temperature and pressure. The fitting procedure is based on Jacobian matrix containing transmission derivatives on free parameters: temperature, CO2 density and H2O density. The clue contribution to an optimal estimation comes from the molecular cross sections derivatives on temperature; they differ significantly from line to line in the considered spectral range. Thanks to that, an independent and simultaneous retrieval of temperature and density is possible. Once the altitude profiles of these parameters are estimated at the first iteration, we calculate the atmospheric pressure profile assuming the hydrostatic equilibrium. This assumption was successfully tested by other vertical profile retrievals from the ACS data [1, 5]. The uncertainty of the retrievals is determined by the transmission errors and the Jacobian matrix for each of free parameters. This estimation allows establishing maximal altitudes with a positive detection of CO2 and H2O densities. Results ACS-MIR solar occultations in the 2.65-2.7 μm spectral range provide us with unprecedented capability to profile CO2 density and temperature from 20 to 180 km, covering the troposphere, the mesosphere and the thermosphere of Mars. The homopause varies around ~130 km and CO2 mixing ratio decreases from 96% to 20-40% at 180 km due to photolysis and molecular diffusion. In parallel with the same dataset, we report very high altitude water abundance, at 110-120 km, that occurred in the southern spring and summer including the GDS and the perihelion in the 34th Martian Year. However, our measurements in the northern hemisphere revealed such a high H2O enrichment only at the stormy events. Comparison of our climatology with some improvements in the Global Circulation Model for the MY34 is in progress. Acknowledgements The retrievals of density/temperature profiles in IKI are funded by the RSF grant #20-42-09035. References [1] Korablev O. et al., 2018. The Atmospheric Chemistry Suite (ACS) of three spectrometers for the ExoMars 2016 Trace Gas Orbiter. Space Sci. Rev., 214:7. DOI 10.1007/s11214-017-0437-6. [2] Fedorova A. et al., 2020. Stormy water on Mars: The distribution and saturation of atmospheric water during the dusty season. Science, eaay9522. DOI: 10.1126/science.aay9522. [3] Fedorova A. et al., 2018. Water vapor in the middle atmosphere of Mars during the 2007 global dust storm. Icarus 300: 440-457. [4] Aoki S. et al., 2019. Water vapor vertical profiles on Mars in dust storms observed by TGO/NOMAD. JGR Planets, 124, 3482-3497. https://doi.org/10.1029/2019JE006109. [5] Alday J. et al., 2019. Oxygen isotopic ratios in Martian water vapour observed by ACS MIR on board the ExoMars Trace Gas Orbiter. A&A, 630, A91. DOI: 10.1051/0004-6361/201936234.

Published
2020

47. CO2 and temperature retrievals in the Mars atmosphere from solar occultation by NOMAD-SO and ACS-MIR: performance and cross validation

Author

Ann Carine Vandele, Ian Thomas, Jose-Juan Lopez-Moreno, Giancarlo Bellucci, Franck Montmessin, Juan Alday Parejo, Loïc Trompet, Bernd Funke, Brittany Hill, Denis Belyaev, Alexander Trokhimovskiy, Oleg Korablev, Justin Erwin, Shohei Aoki, Geronimo L. Villanueva, Miguel Lopez-Valverde, Francisco Gonzalez-Galindo, Manuel López-Puertas, Kevin Olsen, and Manish R. Patel

Subjects
Environmental science, Atmosphere of Mars, Occultation, Cross-validation, Remote sensing
Abstract

We present simultaneous retrievals of vertical profiles of CO2 and temperature obtained from a small sample of solar occultation scans by the NOMAD-SO [1] and ACS-MIR [2] instruments on board the ExoMars Trace Gas Orbiter (TGO). The orbits or scans selected from each instrument's observations are sufficiently close in time and space so that the atmospheric variability plays a minor role and a meaningful comparison of the performance of both instrument channels is possible. This is an on-going work devoted to a proper validation of both instruments. We will present a small selection of retrievals than can be used for a critical analysis of the results obtained and as a first step into the mutual validation of NOMAD-SO and ACS-MIR.1. Instruments and observationsOur work is focussed in the NOMAD-SO and the ACS-MIR channels, those specifically devoted to operational observations in solar occultation. Several groups in the NOMAD and ACS teams are performing retrievals of species abundances from these signals and some are reported in this conference [3,4]. We focus on the retrieval of CO2 and temperature in the 2.7 µm range, the strongest IR bands by this gas in the spectra region coverd by SO and ACS [5]. The spectra correspond to calibrated transmittances derived from SO difraction orders 164 and 165 and from MIR position 4 spectra. About a dozen strong CO2 lines are observed in these spectra up to very high tangent altitudes, around 170-180 km. The present study targets at both solar occultation signals, NOMAD-SO and ACS-MIR, but unfortunately, due to some unexpected miss-alignments among the different channels in each instrument and between NOMAD and ACS, an entirely simultaneous observation of the solar disc as it emerges or hides behind the atmosphere is not possible with both SO and MIR channels. Instead this work study the inversions from the two channels in nearly coincident solar occultations, with small changes in latitude, longitude, solar longitude and time.2. Retrieval Scheme We have performed the present retrievals using an inversion code previously used in the Earth upper atmosphere for routine operations of the MIPAS instrument on board the Envisat mission [6]. The inversion scheme, which has been recently adapted to Mars for limb sounding in emission from the OMEGA spectrometer on board the Mars Express spacecraft [7], is adapted here for occultation observations. At the core of the inversion scheme is the forward model KOPRA (Karlsruhe Optimized and Precise Radiative transfer Algorithm [8] ) and the inversion processor (RCP), jointly developed by the Institute for Meteorology and Climate Research (IMK) and the IAA [9].As mentioned above we used here CO2 calibrated transmittances obtained from routine processing by the PI teams. But before injection into the inversion algorithm, a pre-processing of every orbit or scan is performed in order to correct every spectrum of spurious effects. These are essentially two: residual spectral shifts and artificial bending in single spectra. The magnitude of these two effects changes from order to order and between SO and ACS. In spite of these differences, the pre-processing is conceptually similar to both signals, and is actually performed with the same Python code. Further, the ILS associated to each of the signals is best reproduced by a double gaussian, whose detailed description (parameters describing their FWHM and peak ratios, for example) requires also a precise determination by the user, as apparently it slightly varies with time and observing conditions.It is specially useful to obtain both density and temperature information from a single scan, and this is the purpose of the present study. The simultaneous retrieval from a given scan actually derives a CO2 density profile, and after an iterative process, a temperature profile assuming hydrostatic equilibrium. An adjustment for the pointing is also intruduced, and the aerosol extinction and possible interference from species like H2O are also considered during the inversion to obtain the best fits.3. Results We will discuss the fist comparisons of CO2 and temperatures from NOMAD-SO and ACS-MIR, using a common pre-processing and inversion code. The retrievals perform in a similar manner, as in both cases the number of lines, the ro-vibrational bands and the spectral region are similar. Small differences in noise and spectral resolution have some impact but overall both channels permit sounding the Mars atmosphere up to the upper thermosphere with just one single scan. Averaging kernels indicate effective vertical resolutions around 4-6 km in the middle atmosphere (50-100 km), both in CO2 and temperature. The inversion is affected by heavy dust loading and in general degrades below about 30 km and above 150 km due to saturation and noise, respectively. AcknowledgementsThe IAA/CSIC team acknowledges financial support from the State Agency for Research of the Spanish MCIU through the ‘Center of Excellence Severo Ochoa’ award for the Instituto de Astrofísica de Andalucía (SEV-2017-0709). MALV was funded by grant PGC2018-101836-B-100 (MCIU/AEI/FEDER, EU). ExoMars is a space mission of the European Space Agency (ESA) and Roscosmos. The NOMAD experiment is led by the Royal Belgian Institute for Space Aeronomy (IASB-BIRA), assisted by Co-PI teams from Spain (IAA-CSIC), Italy (INAF-IAPS), and the United Kingdom (Open University). US investigators were supported by the National Aeronautics and Space Administration. References[1] Vandaele et al., Space Science Reviews 214 (5), 2018 [2] Korablev et al., Space. Sci. Rev. 214, 7 (2018). [3] Loic et al., Update on CO2 and temperature profiles retrievals from NOMAD-SO on board ExoMars TGO, contribution to this conference, 2020. [4] Shohei et al., Water vapor vertical profiles on Mars: Results from the first full Mars Year of TGO/NOMAD science operations, contribution to this conference, 2020. [5] Lopez-Valverde et al., Space Sci Rev (2018) 214:29 [6] Funke, B., et al. , Atmos. Chem. Phys., 9(7), 2387–2411, 2009.Funke et al., ACP, 9, 2387–2411, 2009. [7] Jimenez-Monferrer, Icarus in press, 2020 [8] Stiller et al., JQSRT, 72, 249–280, 2002 [9] von Clarmann et al., J. Geophys. Res. 108, 4746, 2003 How to cite: Lopez-Valverde, M. A., Funke, B., Hill, B., Gonzalez-Galindo, F., Aoki, S., Trompet, L., Thomas, I., Villanueva, G., Erwin, J., Olsen, K., Belyaev, D., Trokhimovskiy, A., Alday Parejo, J., Lopez-Puertas, M., Lopez-Moreno, J. J., Montmessin, F., Patel, M., Bellucci, G., Vandele, A. C., and Korablev, O.: CO2 and temperature retrievals in the Mars atmosphere from solar occultation by NOMAD-SO and ACS-MIR: performance and cross validation., Europlanet Science Congress 2020, online, 21 September–9 Oct 2020, EPSC2020-924, 2020

Published
2020

48. Martian visible and ultraviolet dayglow: altitude, latitudinal and seasonal variations observed with NOMAD/TGO

Author

Frank Daerden, José Juan López-Moreno, Jon Mason, Ann Carine Vandaele, Yannick Willame, Bojan Risctic, Benoît Hubert, Shohei Aoki, Jean-Claude Gérard, Leonardos Gkouvelis, Cédric Depiesse, Miguel Lopez-Valverde, Giancarlo Belluci, Manish R. Patel, and Ian Thomas

Subjects
Martian, Altitude, Airglow, medicine, Environmental science, Mars Exploration Program, medicine.disease_cause, Ultraviolet, Astrobiology
Abstract

The OI 557.7 nm green line has been measured in the Martian dayglow for the first time with the UVIS visible-ultraviolet spectrograph on board ESA’s Trace Gas Orbiter (Gérard et al., 2020). The first observations started in April 2019 in a special mode where the spacecraft is tilted to observe the limb with the UVIS nadir channel (Vandaele et al., 2015, Patel et al., 2017). The instrument detected the presence of bright green dayglow emission on every of those observations. The main peak altitude is located near 80 km, and its intensity varies as a result of the changing distance from sun, the local time and latitude of the observations. A second, less pronounced, emission peak is observed near 110 km. Photochemical model simulations (Gkouvelis et al., 2018) used the MCD density distribution (Forget et al., 1999) have been made to understand the sources of this airglow emission. It is able to reproduce the altitude and the brightness of the airglow layer. It indicates that the green line dayglow on Mars is essentially produced by photodissociation of CO2 molecules by solar far ultraviolet radiation (Fox & Dalgarno, 1979). A fraction of the oxygen atoms is formed in the 1S metastable state that produces the green emission. In this presentation, we describe additional dayside observations obtained since December 2019. For this purpose, the spacecraft has been used in a special mode where it is re-oriented so that the UVIS channel observed the sunlit limb (Lopez-Valverde et al., 2018). We analyse the observed limb profile variations and the changing altitude of the peak emission resulting from the variations of the pressure levels in the mesosphere (Gkouvelis et al., 2020). The measured intensities are compared with model calculations of the O(1S) density in the conditions of the observations. The ratio of ultraviolet spectral features relative to the oxygen emission also observed with UVIS will also be analysed. REFERENCES Forget, F. et al., J. Geophys. Res. 104(E10), 24155-24175 (1999). Fox, J.L. & Dalgarno, J. Geophys. Res. 84(A12), 7315-7333 (1979). Gérard, J.C. et al., Nature Astronomy, 1-4 (2020), https://doi.org/10.1038/s41550-020-1123-2 Gkouvelis, L. et al., J. Geophys.Res., 123(12), 3119-3132. (2018). Gkouvelis, L. et al., Icarus, 341, 113666 (2020). López-Valverde M. et al., Space Science Reviews, 214(1), 29 (2018). Patel, M. R. et al., Applied optics, 56(10), 2771-2782 (2017). Vandaele, A. C. et al., Optics Express, 23(23), 30028-30042 (2015).

Published
2020

49. Stump appendicitis

Author

Francisco Miguel, González-Valverde, Pedro, López-Morales, and Lucía, Sánchez-Alonso

Subjects
Postoperative Complications, Appendectomy, Humans, Laparoscopy, Appendicitis
Published
2020

50. Giant Diverticulum of the Sigmoid Colon

Author

Miguel Ruiz-Marín, Beatriz Madrid-Baños, and Francisco Miguel González-Valverde

Subjects
medicine.medical_specialty, Sigmoid Diseases, business.industry, General surgery, Gastroenterology, Sigmoid colon, medicine.disease, Diverticulum, Colon, Diverticulum, medicine.anatomical_structure, Colon, Sigmoid, Medicine, Humans, Surgery, business
Published
2020

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