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2 results on '"Meynet, Ilaria"'

1. Impact of different left bundle branch definitions on cardiac resynchronization therapy response and clinical outcomes

Author

Castagno, Davide, Golzio, P. g., Budano, C., De Bonis, C., Meynet, Ilaria, Bisi, Marta, Iannaccone, Mario, Anselmino, Matteo, Giustetto, Carla, Ferraris, F., Battaglia, A., Matta, M., Pozzi, R., and Gaita, Fiorenzo

Subjects
Left Bundle Branch Block, Heart failure, Heart failure, Cardiac Resynchrozation Therapy, Left Bundle Branch Block, Cardiac Resynchrozation Therapy
Published
2016

2. Outcomes of Patients Undergoing Balloon Aortic Valvuloplasty in the TAVI Era: A Multicenter Registry

Author

Moretti, C., Chandran, S., Vervueren, P. -L, D Ascenzo, F., Marco Barbanti, Weerackody, R., Boccuzzi, G., Lee, D. -H, La Torre Hernandez, J., Omedè, P., Nijenhuis, V., Igbineweka, N., Lim, P., Berg, T., Carriè, D., Hildick-Smith, D., Gulino, S., Cannata, S., Gargiulo, G., Tamburino, C., Conrotto, F., Meynet, I., Quadri, G., Marangoni, L., Taha, S., Biondi-Zoccai, G., Salizzoni, S., Marra, S., Gaita, F., Moretti, Claudio, Chandran, Sujay, Vervueren, Paul-Loui, D'Ascenzo, Fabrizio, Barbanti, Marco, Weerackody, Roshan, Boccuzzi, Giacomo, Lee, Dae-Hyun, de la Torre Hernandez, Jose, Omedè, Pierluigi, Nijenhuis, Vincent, Igbineweka, Norri, Lim, Patrick, ten Berg, Null, Carriè, Didier, Hildick-Smith, David, Gulino, Simona, Cannata, Stefano, Gargiulo, Giuseppe, Tamburino, Corrado, Conrotto, Federico, Meynet, Ilaria, Quadri, Giorgio, Marangoni, Ludovica, Taha, Salma, Biondi-Zoccai, Giuseppe, Salizzoni, Stefano, Marra, Sebastiano, and Gaita, Fiorenzo

Subjects
Aged, 80 and over, Balloon Valvuloplasty, Male, Cardiac Catheterization, Time Factors, Time Factor, Risk Factor, Aortic Valve Stenosis, Aortic Valve Stenosi, Follow-Up Studie, Female, Follow-Up Studies, Humans, Retrospective Studies, Risk Factors, Transcatheter Aortic Valve Replacement, Treatment Outcome, Heart Valve Prosthesis, Registries, Heart Valve Prosthesi, Retrospective Studie, 80 and over, Human, Aged
Abstract

Few clinical data about indications and prognoses of patients undergoing balloon aortic valvuloplasty (BAV) in the transcatheter aortic valve implantation (TAVI) era have been reported.Data from all consecutive patients undergoing BAV in seven European centers from 2006 to 2013 were collected. Acute results and long-term outcomes were assessed.A total of 811 patients aged 82 ± 9 years were included; 416 patients (51%) underwent BAV as palliative destination therapy, 320 patients (40%) as bridge to TAVI, and 75 patients (9%) as bridge to surgical aortic valve replacement (SAVR). Patients undergoing BAV as destination therapy had a higher risk profile (logistic EuroSCORE, 20 ± 17 vs 22 ± 14 vs 11 ± 8, respectively; P.001). Post procedure, peak gradient decreased from 87 ± 22 mm Hg to 66 ± 22 mm Hg (P.001) and aortic valve area increased from 0.61 ± 0.2 cm2 to 0.8 ± 0.2 cm2 (P.001). At 30 days, the all-cause death rate (6.5% vs 6.2% vs 7.4%, respectively; P=.56) and the rate of life-threatening and major bleedings (8.0% vs 5.7% vs 6.0%, respectively) did not differ between groups. After a mean follow-up of 318 days (range, 116-500 days), rates of all-cause death were similar (30% vs 34% vs 31%, respectively; P.99), although patients undergoing BAV as bridge to SAVR showed a lower cardiovascular death rate (11% vs 11% vs 3%, respectively; P=.04).In the TAVI era, BAV may represent a reasonable option for patients with severe aortic stenosis and temporary contraindications to definite therapy. Given the mortality rates at 30 days, patients should be carefully selected, while events at follow-up are deeply influenced by the decision of whether or not subsequent interventions are performed.

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