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Supplemental Material for The Effect of COVID-19 on Spine Surgery by Emily S. Mills MD, Ethan Faye BS, Kevin Mertz BS, Andy Ton BS, Jeffrey C. Wang MD, Raymond J. Hah MD, and Ram K. Alluri MD in Global Spine Journal

Ioanna K Bolia, Kevin Mertz, Ethan Faye, Justin Sheppard, Sagar Telang, Jacob Bogdanov, Laith K Hasan, Aryan Haratian, Denis Evseenko, Alexander E Weber, Frank A Petrigliano USC Epstein Family Center for Sports Medicine at Keck Medicine of USC, Los Angeles, CA, USACorrespondence: Ioanna K Bolia, 1520 San Pablo Street Suite 2000, Los Angeles, CA, 90033, USA, Tel +1 9703432813, Fax +1 818-658-5925, Email frank.petrigliano@med.usc.eduAbstract: Knee fibrosis is characterized by the presence of excessive connective tissue due to dysregulated fibroblast activation following local or systemic tissue damage. Knee fibrosis constitutes a major clinical problem in orthopaedics due to the severe limitation in the knee range of motion that leads to compromised function and patient disability. Knee osteoarthritis is an extremely common orthopedic condition that is associated with patient disability and major costs to the health-care systems worldwide. Although knee fibrosis and osteoarthritis (OA) have traditionally been perceived as two separate pathologic entities, recent research has shown common ground between the pathophysiologic processes that lead to the development of these two conditions. The purpose of this review was to identify the pathophysiologic pathways as well as key molecules that are implicated in the development of both knee OA and knee fibrosis in order to understand the relationship between the two diagnoses and potentially identify novel therapeutic targets.Keywords: fibrosis, molecules, knee, osteoarthritis

Supplemental material, sj-pdf-1-fao-10.1177_24730114221126719 for Triceps Surae Lengthening in Foot and Ankle Trauma: A Survey of OTA and AOFAS Members by Joseph T. Patterson, Sean T. Campbell, Stephen J. Wallace, Erik A. Magnusson, Iain S. Elliott, Kevin Mertz and Stephen K. Benirschke in Foot & Ankle Orthopaedics

Supplemental material, sj-pdf-1-fao-10.1177_24730114221126719 for Triceps Surae Lengthening in Foot and Ankle Trauma: A Survey of OTA and AOFAS Members by Joseph T. Patterson, Sean T. Campbell, Stephen J. Wallace, Erik A. Magnusson, Iain S. Elliott, Kevin Mertz and Stephen K. Benirschke in Foot & Ankle Orthopaedics

Supplemental Material for The Incidence of Double Crush Syndrome in Surgically Treated Patients by Emily S. Mills, MD, Kevin Mertz, BS, Zoe Fresquez, BS, Andy Ton, BS, Zorica Buser, PhD, MBA, Ram K. Alluri, MD, and Raymond J. Hah, MD in Global Spine Journal.

Supplemental material, sj-docx-1-han-10.1177_15589447211028919 for Outcome Metrics in the Treatment of Distal Radius Fractures in Patients Aged Above 50 Years: A Systematic Review by Nathaniel Fogel, Kevin Mertz, Lauren M. Shapiro, Allison Roe, Sahitya Denduluri and Robin N. Kamal in HAND