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108,049 results on '"Medina, A."'

1. Efficient removal of the recalcitrant metamizole contaminant from drinking water by using a CaLaCoO9 perovskite supported on recycled polyethylene

Author: Ernesto Valadez-Renteria, Christian Perez-Carrasco, Dulce Yolotzin Medina-Velazquez, Vicente Rodriguez-Gonzalez, and Jorge Oliva
Subjects: Environmental Engineering, Environmental Chemistry, General Medicine, General Environmental Science
Published: 2024

2. Joint models of multivariate longitudinal outcomes and discrete survival data with INLA: An application to credit repayment behaviour

Author: Victor Medina-Olivares, Finn Lindgren, Raffaella Calabrese, and Jonathan Crook
Subjects: Bayesian joint models, Information Systems and Management, General Computer Science, Modeling and Simulation, credit prepayment, discrete time, Management Science and Operations Research, Laplace approximation, Industrial and Manufacturing Engineering, OR in banking
Abstract: Survival models with time-varying covariates (TVCs) are widely used in the literature on credit risk prediction. However, when these covariates are endogenous, the inclusion procedure has been limited to practices such as lagging these variables or treating them as exogenous. That leads to possible biased estimators (depending on the strength of the exogeneity assumption) and a lack of prediction framework that consolidates the joint evolution of the survival process and the endogenous TVCs. The use of joint models is a suitable approach for handling endogeneity, however, it comes at a high computational cost. We propose a joint model for bivariate endogenous TVCs and discrete survival data using integrated nested Laplace approximation (INLA). We illustrate the implementation via simulations and build a model for full-prepayment consumer loans. We also propose a methodology for individual survival prediction using the Laplace method that leads to more accurate approximations than comparable approaches. We evidence the superiority of joint models over the traditional survival approach for an out-of-sample and out-of-time analysis.
Published: 2023

3. Effects of hospital facilities on patient outcomes after cancer surgery

Author: Knight, Sr, Chu, K, Lapitan, Mc, Dare, Aj, Pius, R, Shaw, Ca, Drake, Tm, Norman, L, Ademuyiwa, Ao, Adisa, Ao, Aguilera, Ml, Al-Saqqa, Sw, Al-Slaibi, I, Bhangu, A, Biccard, Bm, Brocklehurst, P, Costas-Chavarri, A, Elhadi, M, Fairfield, Cj, Fitzgerald, Je, Ghosh, D, Glasbey, J, Henegouwen, Miv, Ingabire, Jca, Kingham, Tp, Lawani, I, Lieske, B, Lilford, R, Martin, J, Mclean, Ka, Moore, R, Morton, D, Nepogodiev, D, Ntirenganya, F, Pata, F, Pinkney, T, Stephen, R Knight, Catherine, A Shaw, Riinu, Pius, Thomas, M Drake, Lisa, Norman, Adesoji, O Ademuyiwa, Adewale, O Adisa, Maria Lorena Aguilera, Sara, W Al-Saqqa, Ibrahim, Al-Slaibi, Aneel, Bhangu, Bruce, M Biccard, Peter, Brocklehurst, Ainhoa, Costas-Chavarri, Kathryn, Chu, Anna, Dare, Muhammed, Elhadi, Cameron, J Fairfield, J Edward Fitzgerald, Dhruv, Ghosh, James, Glasbey, Mark, I van Berge Henegouwen, C Allen Ingabire, J, T Peter Kingham, Marie Carmela Lapitan, Ismaïl, Lawani, Bettina, Lieske, Richard, Lilford, Janet, Martin, Kenneth, A McLean, Rachel, Moore, Dion, Morton, Dmitri, Nepogodiev, Faustin, Ntirenganya, Francesco, Pata, Thomas, Pinkney, Ahmad Uzair Qureshi, Antonio Ramos-De la Medina, Aya, Riad, Hosni Khairy Salem, Joana, Simões, Richard, Spence, Neil, Smart, Stephen, Tabiri, Hannah, Thomas, Thomas, G Weiser, Malcolm, West, John, Whitaker, Ewen, M Harrison, Arben, Gjata, Maria Marta Modolo, Sebastian, King, Erick, Chan, Sayeda Nazmun Nahar, Ade, Waterman, Dominique, Vervoort, Alemayehu Ginbo Bedada, Bernardo De Azevedo, Ana Gabriela Figueiredo, Manol, Sokolov, Venerand, Barendegere, Gerald, Ekwen, Arnav, Agarwal, Qinyang, Liu, Juan Camilo Correa, Kalisya Luc Malemo, Jacques, Bake, Jakov, Mihanovic, Kamila, Kunčarová, Julius, Orhalmi, Hosni, Salem, Jyri, Teras, Aristotelis, Kechagias, Alexis, P Arnaud, Judith, Lindert, Vasileios, Kalles, Maria-Lorena, Aguilera-Arevalo, Gustavo, Recinos, Zsolt, Baranyai, Basant, Kumar, Harish Neelamraju Lakshmi, Sanoop Koshy Zachariah, Philip, Alexander, Sunil Kumar Venkatappa, Pramesh, C, Radhian, Amandito, Christina, Fleming, Luca, Ansaloni, Gianluca, Pellino, Ahmed, M Altibi, Ibrahim, Nour, Intisar, Hamdun, Ali, M Ghellai, Donatas, Venskutonis, Tomas, Poskus, Justas, Zilinskas, Precious, Malemia, Yong Yong Tew, Elaine, Borg, Sarah, Ellul, Fatima Zahraa Wafqui, David, W Borowski, Anne Sophie van Dalen, Cameron, Wells, Harissou, Adamou, Adesoji, Ademuyiwa, Adewale, Adisa, Kjetil, Søreide, Sara Al Saqqa, Osaid, Alser, Haya, Tahboub, Helmut Alfredo Segovia Lohse, Sebastian Shu Yip, Piotr, Major, António Sampaio Soares, Matei Razvan Bratu, Andrey, Litvin, Armen, Vardanyan, Ahmad, Gudal, Naif, Albati, Jovan, Juloski, Miran, Rems, Sarah, Rayne, Stephanie Van Straten, Yoshan, Moodley, Irene Ortega Vázquez, Jaime, Ruiz-Tovar, Kithsiri Janakantha Senanayake, Sujeewa Priyantha Bandara Thalgaspitiya, Omer Abdelbagi Omer, Anmar, Homeida, Yucel, Cengiz, Daniel, Clerc, Muhammad, Alshaar, Hanen, Bouaziz, Yuksel, Altinel, Matthew, Doe, Maryna, Freigofer, Ella, Teasdale, Rakan, Kabariti, Joshua Michael Clements, Stephen Richard Knight, Ahsan, Ashfaq, Ijeoma, Azodo, Gabriela, Wagner, Ivan, Trostchansky, Mayaba, Maimbo, David, Linyama, Helidon, Nina, Amanda, Zeko, Claudio Gabriel Fermani, Santiago, Villalobos, Federico, Carballo, Pablo, Farina, Sebastian, Guckenheimer, Marilla, Dickfos, Ankit, Ajmera, Chester, Chong, Ralph, Gourlay, Sikandar, Hussaini, Yi Jia Lee, Adeeb, Majid, Peter, Martin, Rebecca, Miles, Owen James Morris, Jamie, Phua, William, Ridley, Tarunpreet, Saluja, Ryan Renxin Tan, Jen, Teh, Anna, Wells, Bharti, Arora, Qaasim, Dollie, Debbie, Ho, Yanru, Ma, Omattage Mahasha Perera, Anthony, Truong, Amanda Caroline Dawson, Bryan, Lim, Upuli, Pahalawatta, Jacqueline, Phan, Xiao-Ming Sarah Woon-Shoo-Tong, Andrea, Yeoh, Lillian, Charman, Andrew, Drane, Sharon, Laura, Charmaine Chu Wen Lo, Amy, Mozes, Rita, Poon, Hao Han Tan, Ellen, Wall, Prakshi, Chopra, Jasmine De Giovanni, Bal, Dhital, Brian, Draganic, Alexander, Duller, Jonathan, Gani, Yao Kuan Goh, Jun Young Jeong, Brendan, Mcmanus, Prakash, Nagappan, Peter, Pockney, Anya, Rugendyke, Mahsa, Sarrami, Stephen, Smith, Vanessa, Wills, Hsu Ven Wong, Geoffrey, Ye, Geoffrey, Zhang, Ethan, Brooker, Daniel, Feng, Bonnie, Lau, Carlin, Ngai, Sarah, Birks, David, Gyorki, Jaime Otero de Pablos, Ali, Abbosh, Chris, Gillespie, Ahmed, Mahmoud, Bianca, Kwan, Joshua, Lawson, Andrea, Warwick, Janne, Bingham, Andrew, J Cockbain, Nagendra Naidu Dudi-Venkata, Jordan, Ellaby-Hall, Ben, Finlay, Emily, Humphries, Jade, Pisaniello, Monique, Pisaniello, Salma, Salih, Tarik, Sammour, Haidar Hadri Abd Wahab, April De Silva, Nicola, Hayward, Kartik, Iyer, Guy, Maddern, Gian Andrea Prevost, Naga, Annapureddy, Krishna Pranathi Settipalli, Jeremy, Yeo, Lucy, Hempenstall, Lily, Pham, Shaun, Purcell, Cherry, Talavera, Ashish, I Vaska, Gurpreet, Chaggar, Phillip, Chrapko, Annelise, Cocco, Sarah Michelle Crystal Jade Coulter-Nile, Grahame, Ctercteko, James, French, Houchen, Gong, Martijn, Gosselink, Thuvarahan, Jegathees, Ivan, Jin, Michelle, Kalachov, Kathryn, Kiefhaber, Katherine, Lee, Jason, Luong, Steven, Phan, Henry, Pleass, Kelly, Veale, Zhi, Zeng, Angela, Au, Ashe, Debiasio, Idy, Deng, Jananee, Myooran, Amrita, Nair, Peter, Stewart, Anton, Stift, Lukas Walter Unger, Kerstin, Wimmer, Nabila, Ahmed, Syed, Hasan, Saber, Rahman, Margaret, O'Shea, Greg, Padmore, Adrian, Peters, Pietro, Perduca, Guenda, Pulcina, Nicolas, Tinton, Frederic, Buxant, Elsa, Dabin, Giulia, Garofalo, Francis, Dossou, Freddy Houehanou Rodrigue Gnangnon, Yacoubou Imorou Souaibou, Pako, Motlaleselelo, Omphile, Tlhomelang, Igor Lima Buarque, Gustavo Mendonça Ataíde Gomes, Aldo Vieira Barros, Ilia, Batashki, Nikolai, Damianov, Vladislav, Stoyanov, Dragomir, Dardanov, Svilen, Maslyankov, Plamen, Petkov, George, Todorov, Evgeni, Zhivkov, Aygulya, Akisheva, Miguel Angel Castilla Moreno, Geno, Genov, Ivelina, Ilieva, Tsvetomir, Ivanov, Martin, Karamanliev, Azhar, Khan, Emil, Mitkov, Tsanko, Yotsov, Boyko, Atanasov, Nikolay, Belev, Mihail, Slavchev, Carlos, Nsengiyumva, Elgan, Jones, Simon, Stock, Steve, Kyota, James, Brown, Tresor Mabanza, K, Lemery Nigo Samuel, Chidi, Otuneme, Ngwang, Prosper, Franklin, Umenze, Marylise, Boutros, Natasha, Caminsky, Sinziana, Dumitra, Richard, Garfinkle, Dominique, Morency, Ebram, Salama, Alexander, Banks, Lorenzo, Ferri, Haitian, He, Amit, Katz, Alexander Sender Liberman, Sarkis, Meterissian, Allison, Pang, Elena, Parvez, Usmaan, Hameed, Fahima, Osman, Sangita, Sequeira, Natalie, Coburn, Alisha, Jaffer, Paul, Karanicolas, Matthew, Mosseler, Reilly, Musselman, Xinyuan, Liu, Ching Wan Yip, Juan Sebastian Garces-Otero, Carolina, Guzman, Sebastian, Sierra, Andres Uribe Valencia, Paulo Andrés Cabrera Rivera, Saul, Camelo, Andrea, Gonzalez, Alejandro, González-Orozco, Manuel Santiago Mosquera Paz, Carlos J- Perez Rivera, Felipe, Gonzalez, Andres, Isaza-Restrepo, Laura, Nino-Torres, Natalia Arias Madrid, Maria Clara Mendoza Arango, Justin, Tsandiraki, Damir, Jemendžić, Branislav, Kocman, Oliver, Šuman, Renata, Canic, Darko, Jurišić, Ivana, Karakas, Ana Krizanovic Rupcic, Vlatka, Pitlovic, Josip, Samardžić, Mario, Kopljar, Ivan, Bacic, Edgar, Domini, Robert, Karlo, Danijela, Miljanić, Andrea, Simic, Mariam, Ahmed, Majdi Al Nassrallah, Rabiya, Altaf, Talal, Amjad, Ruba, Eltoum, Heba, Haidar, Alhassan, Hassan, Omar, Khalil, Marwan, Qasem, Rommel, Ramesh, Gautham, Sajith, Maham, Wisal, Jan, Žatecký, Michele, Bujda, Katerina, Jirankova, Ales, Paclik, Aya, Abdallah, Mariam Abdulgawad Almogy, Esraa Ayman El-Sawy, Ahmed Moustafa ElFayoumy, Nourhan, Elghareeb, Nourhan Ahmed Esmat, Ahmed, Fadel, Abdullah, Habater, Heba, Hamdy, Amr, Hefni, Marwa, Kamal, Norhan Mohamed Abobakr, Ahmed, Sayed, Nancy, Shaker, Ehab, Taha, Hoda, Tharwat, Omar, Zakaria, Ibrahem, Abdelmotaleb, Ali, Al-Dhufri, Hamza, S Al-Himyari, Enas El Sheikh, Asmaa, Eldmaty, Aya, Elkhalawy, Ahmed, M Elkhashen, Kithara, Magdy, Safa, Mostafa, Habib Doutoum Sadia, Mohamed Mahmoud Saleh, Dina, Samir, Mohamed Yahia Mohamed Ali, Mahmoud, A Nassar, Samar, Abdelhady, Aly, Abdelrazek, Israa, Abdelsalam, Aya, El-Sawy, Eman, Essam, Mohamed, Gadelkarim, Khaled, Ghaly, Mohamed, Hassabalnaby, Rana, Masarani, Nourhan Mohamed Shaaban, Ahmed, Sabry, Menatalla, Salem, Nourhan Akram Soliman, Diaaaldin, Zahran, Moustafa Ramadan Abou El Soud, Esraa Tarek Badr, Hala, Borham, Nehal, Elmeslemany, Mohammad, Elsayed, Fawzia, Elsherif, Sara, Eslam, Gehad, Gaber, Sondos, Ibrahim, Yara, Kamh, Abdelrahman, Mahmoud, Shimaa Gamal Mohamed, Eman, Morshedy, Cinderella, Omar, Fatima Salem Soliman, Shaza, Abdelkawy, Naglaa, Abdelmohsen, Mahmoud, Abdelshakour, Ahmed, Dahy, Norhan, Gamal, Mohammed, Gamal, Ahmad, Hasan, Helal, Hetta, Nehad, Mousa, Mohamed, Omar, Somia, Rabie, Mahmoud, Saad, Bakeer, Saleh, Marwa Sayed Mohamed, Muhammad, Shawqi, Heba Abdelhady Mousa, Mostafa, Alnoury, Mohamed, Elbealawy, Ahmed, Elshafey, Muhammad Essam Ibrahim El Desouki Muhammad Ahmed, Mennatullah, Ghonaim, Fawzy, Hgag, Mohamed, Ibrahim, Mahmoud, Morsy, Mohamed Reda Loaloa, Ahmed, Refaat, Hadeer, Samir, Fatma, Shahien, Mohamed, Sobhy, Fathy, Sroor, Esraa, Abdellatif, Marina, Adel, Amr Abdelghani Afifi, Eman, Afifi, Marco, Antaky, Amr, Dawoud, Naira El Zoghby, Amira, El-Remaily, Ali Abdelazez Elzanfaly, Ahmed, Gadallah, Fatma Alzahraa Gamal, Omar, Hashem, Shrouk Medhat Youssef, Aliaa Muhammad Attyah, Malak, Munir, Omar, Shazly, Esraa, Taha, Karim, Wilson, Sawsan, Adel, Asmaa, Ali, Esraa, Eid, Esraa, Elhelow, Marwa, Elmahdy, Bassant, Elshatby, Amany Hossam El-Din Zakaria, Ahmad, Hossny, Eman, Ibrahim, Ahmed, M Yonis, Maram, Metwalli, Basant, Yousry, Esraa, Zid, Mina, A Yacoub, Ahmed, Abdelhakim, Nervana, Abouelsoad, Mo'Min, Alkhatib, Ahmed, Ashraf, Alaa, Ashraf, Yasmin, Elazab, Mahmoud, Elfanty, Osama, Elkabir, Mai, Elsayed, Ahmed, Elshimy, Hager, Elsobky, John, Eskander, Ahmed, Gad, Ward, Hamsho, Noura Khaled Abdelwahed, Menna, Magdy, Dalia, Moharam, Abeer, Osama, Shereen, Ramadan, Radwa, Roum, Taqwa, Sayed, Tarneem, Shehada, Ahmed Mohy Zidan, Khalid, Abbas, Amr, Ali, Mohamed, Attia, Mohamed, Balata, Ayman El Nakeeb, Mohamed Ibrahim Elsayed Elewaily, Ahmed, Elfallal, Hossam, Elfeki, Ahmed, Elkhadragy, Sameh, Emile, Helmy, Ezzat, Hasnaa, Hosni, Islam, Mansour, Waleed, Omar, Gehad, Othman, Kareem, Sadek, Mostafa, Shalaby, Noura, Shehab-Eldeen, Rawda Anas Khalifa, Helmy, Badr, Mostafa, Eldeep, Ahmed, Eldeep, Amany Eldoseuky Mohammed, Salwa, Khallaf, Eman Magdy Hegazy, Rokia, Mahmoud, Pola, Mikhail, Mahmoud, Morsi, Sara, Mowafy, Dina, Raafat, Amina, Safy, Marwa, Sera, Ahmed Shible Sera, Mostafa Salim Mohamed AbdAllah, Muhammad, Abdelkader, Abdulrahman Osama Abdou, Ahmedgaber, Ahmed, Shireen, Gaafar, Fatma Ibrahim Negm, Mina, Lapic, Ahmed, Maher, Hagar, Mahmoud, Ahmed, Mostafa, Mohamed, Samir, Fatma, Samy, Nourhan, Semeda, Hind, I Shalaby, Alaa, El-Taweel, Ahmed Galal Elnagar, Ahmed Gamal Hemidan, Mohamed, Hussein, Ahmed, A Kandil, Moawad, Mf, Ayat Allah Nasser Hamamah, Mostafa, Soliman, Mohamed, Abdelkhalek, Noura Abdelmaksoud Tawakel, Ahmed Mohamed Abdelwahed, Alrawy, Abdou, Khalid, Atallah, Mohammed Yasser Elsherbeny, Eman, Emara, Mohamed, Hamdy, Omar, Hamdy, Amira, Haron, Salma, Ismail, Islam Hany Metwally, Nihal Mohamed Hamed Elgaml, Ahmed, Nassar, Basel, Refky, Mirna, Sadek, Mahmoud, Saleh, Asmaa, Yunes, Mai, Zakaria, Mohammed, Zuhdy, Notila, Fayed, Mohammed Mustafa Hassan Mohammed, Sander, Kütner, Priit, Melnik, Indrek, Seire, Toomas, Ümarik, Eppu, Ainoa, Verner, Eerola, Hanna, Koppatz, Laura, Koskenvuo, Ville, Sallinen, Sini, Takala, Jevgeni, Katunin, Arto, Turunen, Niki, Christou, Muriel, Mathonnet, Vincent, Lavoue, Krystel Nyangoh Timoh, Lucie, Soulabaille, Romain, Lesourd, Aude, Merdrignac, Laurent, Sulpice, Benoît, André, Elodie, Chantalat, Charlotte, Vaysse, Bertrand, Dousset, Sebastien, Gaujoux, Gregory, Martin, Octavian, Clonda, Domantas, Juodis, Klaus, Kienle, Andras, Mravik, Samuel, Palmer, Gabor, Szabadhegyi, Anita Eseenam Agbeko, Solomon, Gyabaah, Frank Enoch Gyamfi, Nuhu, Naabo, Atta Owusu Senior, Joseph, Yorke, Frank, Owusu, Francis, Abantanga, Theophilus Teddy Kojo Anyomih, Abdul-Jalilu Mohammed Muntaka, Emmanuel Owusu Abem, Mohammed, Sheriff, Paul, M Wondoh, Dimitrios, Balalis, Dimitrios, Korkolis, Georgios, Gkiokas, Eirini, Pantiora, Theodosios, Theodosopoulos, Argyrios, Ioannidis, Konstantinos, Konstantinidis, Sofia, Konstantinidou, Nikolaos, Machairas, Anna, Paspala, Anastasia, Prodromidou, Christos, Chouliaras, Konstantinos, Papadopoulos, Ioannis, Baloyiannis, Ioannis, Mamaloudis, George, Tzovaras, Ioanna, Akrida, Maria-Ioanna, Argentou, Stylianos, Germanos, Evangelos, Iliopoulos, Ioannis, Maroulis, George, Skroubis, George, Theofanis, Christos, Chatzakis, Orestis, Ioannidis, Lydia, Loutzidou, Panagiotis, Karathanasis, Nikolaos, Michalopoulos, Charalampos, Theodoropoulos, Dimitrios, Theodorou, Tania, Triantafyllou, Zoe, Garoufalia, Natasha, Hasemaki, Michalis, Kontos, Gregory, Kouraklis, Stylianos, Kykalos, Theodore, Liakakos, Eustratia, Mpaili, Alexandros, Papalampros, Dimitrios, Schizas, Athanasios, Syllaios, Ekaterini Christina Tampaki, Antonios, Tsimpoukelis, Maria Ioanna Antonopoulou, Eirini, Deskou, Dimitrios, K Manatakis, Dimitrios, Papageorgiou, Menelaos, Zoulamoglou, Christos, Anthoulakis, Michalis, Margaritis, Nikolaos, Nikoloudis, Veronica, Campo, André, Ceballos, Mario-Andrés, Flores, Waleska, Giron, Donghyun, Ko, Gabriel, Martinez, Verónica Rivera Lara, Nataly, Rueda, Andres, Sanchez, Jorge Carlos Guillermo Tejeda Garrido, Alvaro Eduardo Alvarez Rivera, Elvis Benjamin Bamaca Ixcajoc, Lilian Elizabeth Barreda Zelaya, Patricia, Chacòn-Herrera, Ligia Margarita Corea Ruiz, Guillermo, Echeverria-Davila, Mario, Garcia, Danilo, García, Edgar Fernando Gutiérrez Mayen, Noriega, José, Nery, Mazariegos, Diego, Méndez, Michael Paniagua Espinoza, David, Bardos, Marton, Benke, Kristof, Illes, Balint András Kokas, Réka, Szabó, Akhila, Appukuttan, Anjitha, Asok, D K, Vijaykumar, Kapil, Malik, Praveen, Ravishankaran, Ritesh, Tapkire, Guru, Moorthy, Joyner, Abraham, Ramesh, Muthuvel, John, Alapatt, Abhay, Kattepur, Nizamudheen, Pareekutty, Mebanshanbor, Garod, Caleb, Harris, Cliff, Wanniang, Ashish, Gupta, Deepak, Nehra, Sanjeev, Parshad, Rajgopal, Acharya, Rajendra, Badwe, Manish, Bhandare, Urvashi, Jain, Karishma, Kirti, Nita, Nair, Shailesh, Shrikhande, Purvi, Thakkar, Premkumar, Anandan, C S, Archana, Arun Holenarasipur Narasannaiah, Tejaswi, Jagarlamudi, M R, Rashmi, Mallikarjuna, Manangi, Abhishek, Raghavendra, K Seshagiri Rao, Vinay, S, Vinay, Sajjan, Aneesh, Shenoy, Santhosh Shivashankar Chikkanayakanahalli, Kavya, Tharanath, Sushmita, V, Peter, Adidharma, Raksheeth, Agarwal, Phebe Anggita Gultom, Ghafur Rasyid Arifin, Matthew, Billy, Zatira, Elfizri, Alessa, Fahira, Devi, Felicia, Triana Hardianti Gunardi, Nadya, Johanna, Nadia Rahmadiani Nugrahadi, Sonar Soni Panigoro, Siti, Rahmayanti, Retta Catherina Sihotang, Santi Yuanita Brata, Hadi, Winoto, Nastaran, Barati, Manoochehr, Karami, Hamidreza, Khorshidi, Homa, Naderifar, Mazin, A Abdulla, Maggie, Coleman, Ronan, J Doherty, Rob, Hannon, Brenda, Murphy, Aine, Stakelum, Des, Winter, Lylas, Aljohmani, Richard, Farnan, Yeshey, Seldon, Tanna, Tan, Shriya, Varghese, Mohammad, Alherz, Muaaz, Ather, Mohammad, Bajilan, Vivien, Graziadei, Isobel, Pilkington, Omar, Quidwai, Paul, Ridgway, Haaris, Shiwani, Abd Al-Rahman Tahir, Eimear, Blunnie, Daniel, Burke, Niall, Kennedy, Kate, Macdonagh, Maeve, O'Neill, Siobhan, Rooney, Giuseppe, Falco, Guglielmo, Ferrari, Simone, Mele, Gabriela Elisa Nita, Lara, Ugoletti, Maurizio, Zizzo, Gianmaria, Confalonieri, Giovanni, Pesenti, Fulvio, Tagliabue, Gianluca, Baronio, Deborah, Ongaro, Giacomo, Pata, Bruno, Compagnoni, Renato, Salvadori, Lucio, Taglietti, Nicola, D'Alessandro, Pierpaolo Di Lascio, Giovanni, Pascale, Luca, Bortolasi, Tommaso, Campagnaro, Massimo, Carlini, Giorgio, Lisi, Davide, Lombardi, Corrado, Pedrazzani, Domenico, Spoletini, Giulia, Turri, Paola, Violi, Donato Francesco Altomare, Fabrizio, Aquilino, Nicola, Musa, Vincenzo, Papagni, Arcangelo, Picciariello, Leonardo, Vincenti, Dario, Andreotti, Savino, Occhionorelli, Matteo, Tondo, Stefano Maria Massimiliano Basso, Paolo, Ubiali, Riccardo, Cirelli, Marco Enrico Mario Maino, Guglielmo Niccolò Piozzi, Emanuele, Picone, Rosa, Scaramuzzo, Giovanni, Sinibaldi, Alfonso, Amendola, Lorenzo, Anastasio, Luigi, Bucci, Emanuele, Caruso, Antonio, Castaldi, Sara Di Maso, Vincenza Paola Dinuzzi, Giovanni, Esposito, Maria, Gaudiello, Mariano Cesare Giglio, Paola Antonella Greco, Gaetano, Luglio, Andrea, Manfreda, Ester, Marra, Federica, Mastella, Gianluca, Pagano, Roberto, Peltrini, Vincenzo, Pepe, Michele, Sacco, Viviana, Sollazzo, Giovanni, Spiezio, Ettore, Cianchetti, Nunzia, Menduni, Michele Maria Carvello, Francesca Di Candido, Antonino, Spinelli, Fabio, Corsi, Luca, Sorrentino, Fabio, Marino, Emanuele Luigi Giuseppe Asti, Luigi, Bonavina, Emanuele, Rausa, Martina, Asta, Andrea, Belli, Francesco, Bianco, Carmela, Cervone, Paolo, Delrio, Armando, Falato, Andrea Fares Bucci, Rita, Guarino, Ugo, Pace, Daniela, Rega, Emilia De Luca, Gaetano, Gallo, Giuseppe, Sammarco, Giuseppe, Sena, Giuseppina, Vescio, Letizia, Santandrea, Giampaolo, Ugolini, Davide, Zattoni, Nicola, Chetta, Gaetano, Logrieco, Serafino, Vanella, Gianluca, Garulli, Nicola, Zanini, Andrea, Bondurri, Francesco, Cammarata, Francesco, Colombo, Diego, Foschi, Giulia Maria Beatrice Lamperti, Anna, Maffioli, Gianluca Matteo Sampietro, Al'Ona, Yakushkina, Gloria, Zaffaroni, Enrico, Cicuttin, Maria Grazia Sibilla, Harmony, Impellizzeri, Marco, Inama, Gianluigi, Moretto, Sylvie, Mochet, Elisa, Ponte, Antonella, Usai, Stefano, Mancini, Andrea, Sagnotta, Luigi, Solinas, Elisa, Bolzonaro, Nicolò, Tamini, Gianluca, Curletti, Raffaele, Galleano, Michele, Malerba, Sofia, Campanella, Gianfranco, Cocorullo, Francesco, Colli, Paolino De Marco, Nicolò, Falco, Tommaso, Fontana, Leonel Jospin Kamdem Mambou, Antonella La Brocca, Leo, Licari, Brenda, Randisi, Giovanna, Rizzo, Giulia, Rotolo, Giuseppe, Salamone, Roberta, Tutino, Paolina, Venturelli, Stefano, Malabarba, Alessandro, Sgrò, Ivan, Vella, Bruno, Cirillo, Daniele, Crocetti, Giorgio De Toma, Pierfrancesco, Lapolla, Andrea, Mingoli, Paolo, Sapienza, Angela, Belvedere, Stefania, Bianchini, Margherita, Binetti, Arianna, Birindelli, Valeria, Tonini, Mauro, Podda, Fabio, Pulighe, Michele De Rosa, Lorenzo, Bono, Felice, Borghi, Paolo, Geretto, Maria Carmela Giuffrida, Corrado, Lauro, Alessandra, Marano, Luca, Pellegrino, Paola, Salusso, Diego, Sasia, Michela, Campanelli, Alberto Realis Luc, Mario, Trompetto, Roberto, Cardia, Nicola, Cillara, Antonio Nicola Giordano, Antonio, Costanzo, Mario Alessandro Giovilli, Luca, Turati, Silvestro, Canonico, Sciaudone, Guido, Francesco, Selvaggi, Lucio, Selvaggi, Nader, Albsoul, Ahmad, Albsoul, Ala'a Aldeen Alkhatib, Osama, Alsallaq, Justin, Z Amarin, Rami, Ayoub, Isam, Bsisu, S El Muhtaseb, M, Mohammad, Jabaiti, Jamal, Melhem, Yasmeen, Z Qwaider, Mohammad Hasan Salameh, Ahmad, Suleihat, Haya, H Suradi, Mohammad, Alammarin, Almoutuz, Aljaafreh, Mohammad Bani Hani, Zeina Bani Hani, Farah Bani Hani, Toqa, Fahmawee, Shadi, Hamouri, Cyrine, Katanani, Ra'Fat, Tawalbeh, Tamara, Tawalbeh, Hassan, Zawahrah, Mohamad, K Abou Chaar, Lana, Abusalem, Mahmoud, Al-Masri, Hani, Al-Najjar, Lutfi, Barghuthi, Zahra, Ahmed, Adnan, Maulana, Omar, Ngotho, Charbel, Kamau, Aruyaru Stanley Mwenda, Fridah, Bosire, Elizabeth, Mwachiro, Robert, Parker, Ian, Simel, Kimutai, Sylvester, Abdulmunem Ahmed Mustafa Althini, Sofian, Elbarouni, Aya Elseed Elbeshina, Ahmed, Gwea, Ans, Malek, Wedad Albashir Masoud Farag, Abdulwahab, Abdalei, Abu Baker Abdel Malik, Areej, Abo-Khammash, Ma'Aly, Abuhlaiga, Nour, Adnan, Marwa, Albaggar, Asma, Alfitory, Asma, Aljanfi, Fakhruddin, Almuzghi, Zohoor, Altumei, Fatima, Alzabti, Hana, Ashoushan, Mohamed, Assalhi, Joma, Azzubia, Sondos, Bnhameida, Malik, Delhen, Houssein, 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Olajide Abiola, Akinlabi Ajao, Anthony Ajiboye, Amarachukwu Etonyeaku, Julius Olaogun, Ademola Adebanjo, Opeoluwa Adesanya, Michael Olatunji Afolayan, Olanrewaju Balogun, Ayomide Makanjuola, Samuel Nwokocha, Rufus Wale Ojewola, Thomas Olagboyega Olajide, Adewale Aderounmu, Abdul-Rashid Adesunkanmi, Adewale Adisa, Augustine Agbakwuru, Adeleke Akeem Aderogba, Olusegun Isaac Alatise, Olukayode Arowolo, Oladejo Lawal, Tajudeen Mohammed, Chinedu Ndegbu, Olalekan Olasehinde, Funmilola Wuraola, Akinbolaji Akinkuolie, Amarachukwu Etonyeaku, Arinzechukwu Mosanya, Omobolaji Ayandipo, Peter Elemile, Taiwo Akeem Lawal, Samuel Ali Sani, Stephen Garba, Rebecca Hauwa Sani, Samson Olori, Henry Onyebuashi, Ifeanyi Umoke, Adedire Adenuga, Ademola Adeyeye, Olufemi Habeeb, Bashir Lawal, Abdulrasheed Nasir, Eirik Kjus Aahlin, Didrik Kjønås, Elisabeth Myrseth, Jibran Abbasy, Abdul Alvi, Omair Saleem, Asma Afzal, Anam Nazir, Muhammad Farooq, Ayesha Liaqat, Syed Asghar Naqi, Ali Raza, Muzna Sarfraz, Muhammad 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A., Braccio, B., Al-Taher, R., Athamneh, S., Parker, A., Sawiee, A., Kattia, A., Tababa, O., Shaeeb, Z., Syminas, V., Jurgaitis, J., Damuleviciene, G., Svagzdys, S., Razafimanjato, N. N. M., Chieng Loo, L., Tiong, I. C., Wan Muhmad, W. F., Vijeyan, H., Li Ying, T., Grech, G., Arrangoiz, R., Jimenez Ley, V. B., Arizpe, D., Lagunes Lara, E., Castro Lopez, E. V., Eaazim, J., Gordinou de Gouberville, M., Bastiaenen, V., Rottier, S., Nahab, F., Ji, M. Y., Seyoji, M., Nwachukwu, C., Emeghara, O., Muhammed, S. E., Idowu, A., Sowemimo, O., Ogundoyin, O., Akande, O., Lott, A., Nadeem, M., Laghari, A. A., Loya, A., Mushtaq, H., Abdullah, M. T., Abuhilal, B., Atawneh, M., Hamdan, H., Alhabil, B., Srour, A., Mousa, I., Da Silva Medina, L., Bartosiak, K., Ferreira, P., Francisco, V., Lemos, R., Frutuoso, L., Fernandes, S., Fonseca, T., Pereira, J., Rachadell, J., Torre, A., Madeira Martins, F., Carvalho, A. 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C., Robertson, H., Lennon, H., Loi, L., Kirkham, E., Mccann, C., Watts, D., Gurung, B., Wilson, M., Tribedi, T., Garofalo, E., Zahra, B., Macdonald, S., Daniels, I., Ng, N., Khosla, S., Olivier, J., Yue, S. Y. P., Suresh, G., Wellington, J., Lorejo, E., Mossaad, M., Crutcher, M., Alimi, M., Baiu, I., Abdou, H., Conway, A., Peck, C., Perdomo Perez, M. A., Zulu, S., Nakazwe, M., Burger, S., Davies, J., Donaldson, R., Ede, C., Garden, O. J., Lesetedi, C., Mabedi, C., Magill, L., Makinde Alakaloko, F., Makupe, A., Monahan, M., Mulira, S., Muller, E., Musowoyo, J., Olory-Togbe, J. L., Roberts, T., Smith, M., Tayler, V., Windsor, J., Yepez, R., Sundar, S., Runigamugabo, E., Verjee, A., Chen, J., Daya, L., El Aroussi, N., Farina, V., Gnintedeme Olivier, T., Gonzales Nacarino, M., Hammani, A., Honjo, S., Jacobs, R., Kimura, H., Nkoronko, M., Oscullo Yepez, J. J., Pin Hung, W., Raj, A., Romani Pozo, A., Rommaneh, M., Sassamela Fabiano, S. C., Shiroma Gago, C. M., Srinivas, A., Sung, C. -Y., Tai, A., Valle Aranda, Y. C., Venturini, S., Wilguens Lartigue, J., Public and occupational health, AMS - Sports, APH - Health Behaviors & Chronic Diseases, CCA - Cancer Treatment and quality of life, Amsterdam Gastroenterology Endocrinology Metabolism, Cancer Center Amsterdam, and Albarella, Sara
Subjects: global surgery, hospitals, humans, income, neoplasms, postoperative period, poverty, prospective studies, no keywords listed, General Medicine, Prospective Studie, Hospital, Settore MED/18 - Chirurgia Generale, outcome, Hospitals, Humans, Income, Neoplasms, surgery, Postoperative Period, Poverty, Prospective Studies, cancer surgery, Human, hospital facilities
Abstract: © 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide. Methods: A multimethods analysis was performed as part of the GlobalSurg 3 study—a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital. Findings: Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3·85 [95% CI 2·58–5·75]; p
Published: 2022

4. The costs of surgical site infection after abdominal surgery in middle-income countries: Key resource use In Wound Infection (KIWI) study

Author: M. Monahan, J. Glasbey, T.E. Roberts, S. Jowett, T. Pinkney, A. Bhangu, D.G. Morton, A.R. de la Medina, D. Ghosh, A.O. Ademuyiwa, F. Ntirenganya, S. Tabiri, L.A. Adagrah, B.B. Alhaji Alhassan, M.P. Amoako-Boateng, A.B. Appiah, A. Asante-Asamani, B. Boakye, S.A. Debrah Donald Enti, R.A. Ganiyu, P. Koggoh, R. Kpankpari, I.N.M. Opandoh, M.A. Manu Maison Patrick Opoku Manu, S. Mensah, M.T. Morna, J. Nkrumah, M. Nortey, E.O. Ofori, E.M. Quartson, A.O. Acquah, L.I. Adam-Zakariah, E. Asabre, R.A. Boateng, B. Koomson, A. Kusiwaa, E.Y. Twerefour James Ankomah, F. Assah-Adjei, A.A. Boakye, G. Fosu, G. Serbeh, K.Y. Gyan, I.O. Nyarko, Z. Robertson, D.O. Acheampong, J. Acquaye, M. Adinku, K. Agbedinu, A.E. Agbeko, E.G. Amankwa, M. Amoah, G. Amoah, J. Appiah, J. Arthur, A. Ayim, E.K. Ayodeji, J. Boakye-Yiadom, E.A. Boateng, C. Dally, A. Davor, C.K. Gyasi-Sarpong, N.N. Noel Hamidu, I. Haruna, N. Kwarley, A.K. Lovi, B. Nimako, B.B. Nyadu, D. Opoku, A. Osabutey, R. Sagoe, S. Tuffour, Y. Tufour, F.A. Yamoah, A.C. Yefieye, J. Yorke, K.G. Addo, E.A. Akosa, P. Boakye, C.L. Coompson, B. Gyamfi, B.E. Kontor, C. Kyeremeh, R. Manu, E. Mensah, F.I. Solae, G.K. Toffah, R. Adu-Brobbey, A.H. Labaran, A. Owusu, V. Adobea, A. Bennin, F. Dankwah, S. Doe, R.S. Kantanka, E. Kobby, H. Larnyor, P.Y. Owusu, C.A. Sie-Broni, M. Zume, F.A. Abantanga, D.R. Abdulai, D.K. Acquah, E. Ayingayure, I. Osman, S. Kunfah, G. Limann, S.A. Mohammed, S. Mohammed, Y. Musah, B. Ofori, E.A. Owusu, A.H. Saba, A.S. Seidu, M. Yakubu, E.M. Ta-ang Yenli, K. Bhatti, J. Dhiman, K. Dhir, M. Hans, P. Haque, A. Suroy, E.D. Mark Jesudason, P. K, L. Madankumar, R. Mittal, I. Nagomy, S. Prasad, A. Dasari, P. Jacob, E. Kurien, A. Mathew, D. Prakash, A. Susan, R. Varghese, R.C. Ortiz, G.H. Gonzalez, R.H. Krauss, L.H. Miguelena, M.H. Romero, I.B. Gomez, C.C. Aguirre, A.C. Avendaño, L.D. Sansores, H.O. Mejia, L.U. Gomez del Campo, I.D. Sánchez, D.G. Vazquez, M.M. Lara, L.M. Perez Maldonado, A.N. Sainz de la Fuente, A.R. De la Medina, V. Adeleye, A. Ademuyiwa, O. Adeniyi, O. Akinajo, D. Akinboyewa, I. Alasi, F. Alakaloko, O. Atoyebi, O. Balogun, O. Belie, C. Bode, A. Ekwesianya, O. Elebute, F. Ezenwankwo, A. Fatuga, G. Ihediwa, A. Jimoh, J. Kuku, O. Ladipo-Ajayi, A. Makanjuola, O. Mokwenyei, S. Nwokocha, O. Ogein, R. Ojewola, A. Oladimeji, T. Olajide, O. Oluseye, J. Seyi-Olajide, A. Soibi-Harry, A. Ugwu, E. Williams, L. Abdur-Rahman, N. Adeleke, M. Adesola, R. Afolabi, S. Agodirin, I. Aremu, J. Bello, S. Lawal, A. Lawal, H. Raji, O. Sayomi, and A. Shittu
Subjects: Microbiology (medical), Infectious Diseases, General Medicine
Published: 2023

5. Ambiente hospitalario, funcionamiento familiar y afrontamiento activo como predictores de la adherencia al tratamiento farmacológico en pacientes con diabetes mellitus tipo 2

Author: Nissa Yaing Torres Soto, Josué Arturo Medina Fernández, María de Lourdes Rojas Armadillo, Isaí Arturo Medina Fernández, Hugo Alejandro Panting Villalobos, Saul David Badillo Perry, and Gabriela Alejandrina Suárez Lara
Subjects: General Earth and Planetary Sciences, General Environmental Science
Abstract: La diabetes mellitus tipo 2 (DMT2) representa un problema de salud pública en México por los altos índices de morbilidad y mortalidad debido a la falta de adherencia al tratamiento farmacológico. El objetivo fue analizar la adherencia al tratamiento farmacológico mediante un modelo de ecuaciones estructurales. A través de un estudio cuantitativo, no experimental, descriptivo, transversal y correlacional-explicativo, se trabajó con una muestra por conveniencia de 261 personas con DMT2 (64% mujeres y 36% hombres), con una media de 52.93 años y diagnóstico de DMT2 en Chetumal, Quintana Roo, México. El modelo estructural demostró que el ambiente hospitalario y el funcionamiento familiar tuvieron un efecto positivo y significativo en la adherencia al tratamiento farmacológico; a su vez, estos dos factores de segundo orden mediaron la adherencia al tratamiento farmacológico a través de las estrategias de afrontamiento activo.
Published: 2023

6. Tribus urbanas y salud. Apuntes desde Cuba

Author: Rosa María Medina Borges, Amalia Álvarez Medina, Talía Méndez Llerena, and Susana Solís Solís
Subjects: General Medicine
Abstract: El artículo se propone:valorar la influencia de las tribus urbanas en el comportamiento social y la salud de los jóvenes cubanos que pertenencen a ellas. Se presenta una articulación basada en criterios de autores, tanto de las Ciencias Sociales como de las Ciencias Médicas, conla búsqueda de la interrelaciónentre las categorías identidad (es) y juventud(es), principales tribus urbanas que existen en Cuba, su comportamiento social y las posibles implicaciones para la salud de sus miembros. Se significael rol de enfermeros/as ymédicos(as) en la prevención, detección, y acompañamiento de los(las)jóvenes.Durante la etapa juvenil, los proyectos de vida juegan un rol protagónico, no obstante, la búsqueda y alcance de esas metas no transcurre de manera lineal ni armónica. El(la)profesional de la salud deberealizar una labor personalizada en la prevención de las adicciones, con grupos vulnerables o de alto riesgo.
Published: 2023

7. Tecnologías de la información y comunicación y satisfacción académica en los estudiantes de una universidad de Ecuador, 2020

Author: César Rolando Mera Mendoza, Marco Yamil Medina Ruíz, Alberto Javier Montoya Zamora, Patricia Alexandra Medina Mariño, and Silvia Gricelda Suárez Anchundia
Subjects: General Medicine
Abstract: La presente investigación tiene como objetivo determinar la relación que existe entre las Tecnologías de la Información y Comunicación y la satisfacción académica en los estudiantes de una universidad de Ecuador, 2020. La investigación realizada fue de enfoque cuantitativo, tipo básico, de nivel descriptivo, diseño no experimental, correlacional de corte transversal. La población del estudio estuvo conformada por 32 estudiantes del IV módulo de la carrera de Ingeniería Agroindustrial de la Universidad Técnica Estatal de Quevedo, a quienes se les tomó como unidades de análisis, aplicando el muestreo no probabilístico intencionado por conveniencia. La recolección de datos se llevó a cabo utilizando la técnica de la encuesta y los instrumentos empleados fueron los cuestionarios para medir el uso de las TIC y la satisfacción académica que previamente estuvieron validados por juicio de expertos con un resultado de aplicabilidad; la confiabilidad se determinó mediante el coeficiente de Alfa de Cronbach cuyo valor fue 0,947 para la variable Tecnologías de la información y comunicación y 0,961 para la variable satisfacción académica en estudiantes universitarios. Los resultados para establecer el grado de correlación tenemos que el Rho de Spearman es igual a (Sig.=0.002
Published: 2023

8. Combined exposure to alcohol and cannabis during development: Mechanisms and outcomes

Author: Martina V. Kovács, Helenice Charchat-Fichman, J. Landeira-Fernandez, Alexandre E. Medina, and Thomas E. Krahe
Subjects: Behavioral Neuroscience, Health (social science), Neurology, General Medicine, Toxicology, Biochemistry
Published: 2023

9. Design Optimization, Cabling and Stability of Large-Diameter High Jc Nb3Sn Wires

Author: S. C. Hopkins, B. Medina-Clavijo, C. Barth, J. Fleiter, and A. Ballarino
Subjects: Electrical and Electronic Engineering, Condensed Matter Physics, Accelerators and Storage Rings, Electronic, Optical and Magnetic Materials
Abstract: In the framework of the High Field Magnets (HFM) program, CERN is developing and qualifying Nb 3 Sn Rutherford cables to support magnet development towards the requirements of a future energy-frontier collider, using both state-of-the-art commercial wires and experimental wires under development with industrial partners. The trend towards higher current density and larger diameter wires imposes challenges for magneto-thermal stability. In this study, rolling trials and Rutherford cabling have been performed at CERN for two designs of a 1 mm diameter distributed tin Nb 3 Sn wire produced by KAT, and for 1 mm and 1.1 mm diameter RRP® Nb 3 Sn wires procured from Bruker OST, and the self-field stability and cabling degradation have been analyzed. The 1 mm RRP® wire shows significant degradation in Ic and stability on cabling. Although the latter is not expected to impact the performance of research magnets, the potential of heat treatment optimization to improve stability has also been quantified. The distributed tin wire shows substantially poorer stability, but promising indications of low cabling degradation. The influence of wire design characteristics on cabling behavior and stability have been assessed, and the implications for future wire optimization towards high field accelerator magnet applications have been discussed.
Published: 2023

10. Wave climate and energy resources in American Samoa from a 42-year high-resolution hindcast

Author: Gabriel García Medina, Zhaoqing Yang, Ning Li, Kwok Fai Cheung, and Elinor Lutu-McMoore
Subjects: Renewable Energy, Sustainability and the Environment
Published: 2023

11. The origin of pleasant sensations: Insight from direct electrical brain stimulation

Author: Cécile Villard, Zoé Dary, Jacques Léonard, Samuel Medina Villalon, Romain Carron, Julia Makhalova, Stanislas Lagarde, Christophe Lopez, Fabrice Bartolomei, Laboratoire de Neurosciences Cognitives [Marseille] (LNC), Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Institut de Neurosciences des Systèmes (INS), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Service de neurophysiologie clinique [Hôpital de la Timone - APHM], and Hôpital de la Timone [CHU - APHM] (TIMONE)
Subjects: direct electrical brain stimulation, stereoelectroencephalography, Neuropsychology and Physiological Psychology, AI, SEEG, Cognitive Neuroscience, direct electrical brain stimulation SEEG, Brain stimulation Positive emotion Stereoelectroencephalography Amygdala Insula EBS, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Experimental and Cognitive Psychology, anterior insula, stereoelectroencephalography AI
Abstract: International audience; Research into the neuroanatomical basis of emotions has resulted in a plethora of studies over the last twenty years. However, studies about positive emotions and pleasant sensations remain rare and their anatomical-functional bases are less understood than that of negative emotions. Pleasant sensations can be evoked by electrical brain stimulations (EBS) during stereotactic electroencephalography (SEEG) performed for pre-surgical exploration in patients with drug-resistant epilepsy. We conducted a retrospective analysis of 10 106 EBS performed in 329 patients implanted with SEEG in our epileptology department. We found that 13 EBS in 9 different patients evoked pleasant sensations (.60% of all responses). By contrast we collected 111 emotional responses of negative valence (i.e., 5.13% of all responses). EBS evoking pleasant sensations were applied at 50 Hz with an average intensity of 1.4 ± .55 mA (range .5e2 mA). Pleasant sensations were reported by nine patients of which three patients presented responses to several EBS. We found a male predominance among the patients reporting pleasant sensations and a prominent role of the right cerebral hemisphere. Results show the preponderant role of the dorsal anterior insula and amygdala in the occurrence of pleasant sensations.
Published: 2023

12. Kidney and Cardiovascular Effects of Canagliflozin According to Age and Sex

Author: Tae Won Yi, Brendan Smyth, Gian Luca Di Tanna, Clare Arnott, Kathryn Cardoza, Amy Kang, Carol Pollock, Rajiv Agarwal, George Bakris, David M. Charytan, Dick de Zeeuw, Hiddo J.L. Heerspink, Bruce Neal, David C. Wheeler, Christopher P. Cannon, Hong Zhang, Bernard Zinman, Vlado Perkovic, Adeera Levin, Kenneth W. Mahaffey, Meg Jardine, Barry M. Brenner, Tom Greene, Meg J. Jardine, Gary Meininger, Nicole Li, Inna Kolesnyk, Diego Aizenberg, Roberto Pecoits-Filho, David Cherney, Gregorio Obrador, Glenn Chertow, Tara Chang, Carmel Hawley, Linong Ji, Takashi Wada, Vivekanand Jha, Soo Kun Lim, Mary Anne Lim-Abrahan, Florence Santos, Dong-Wan Chae, Shang-Jyh Hwang, Evgueniy Vazelov, Ivan Rychlík, Samy Hadjadj, Vera Krane, László Rosivall, Luca De Nicola, Alexander Dreval, Michał Nowicki, Adalbert Schiller, Larry Distiller, Jose L. Górriz, Mykola Kolesnyk, null David, C. Wheeler, Rodolfo Andres Ahuad Guerrero, Juan Pablo Albisu, Andres Alvarisqueta, Ines Bartolacci, Mario Alberto Berli, Anselmo Bordonava, Pedro Calella, Maria Cecilia Cantero, Luis Rodolfo Cartasegna, Esteban Cercos, Gabriela Cecilia Coloma, Hugo Colombo, Victor Commendatore, Jesus Cuadrado, Carlos Alberto Cuneo, Ana Maria Cusumano, Walter Guillermo Douthat, Ricardo Dario Dran, Eduardo Farias, Maria Florencia Fernandez, Hernan Finkelstein, Guillermo Fragale, Jose Osvaldo Fretes, Nestor Horacio Garcia, Anibal Gastaldi, Elizabeth Gelersztein, Jorge Archibaldo Glenny, Joaquin Pablo Gonzalez, Patricia del Carmen Gonzalez Colaso, Claudia Goycoa, Gustavo Cristian Greloni, Adrian Guinsburg, Sonia Hermida, Luis Isaias Juncos, Maria Isabel Klyver, Florencia Kraft, Fernando Krynski, Paulina Virginia Lanchiotti, Ricardo Alfonso Leon de la Fuente, Nora Marchetta, Pablo Mele, Silvia Nicolai, Pablo Antonio Novoa, Silvia Ines Orio, Fabian Otreras, Alejandra Oviedo, Pablo Raffaele, Jorge Hector Resk, Lucas Rista, Nelson Rodriguez Papini, Jorgelina Sala, Juan Carlos Santos, Lilia Beatriz Schiavi, Horacio Sessa, Tomas Smith Casabella, Maria Rosa Ulla, Maria Valdez, Augusto Vallejos, Adriana Villarino, Virginia Esther Visco, Alfredo Wassermann, Cesar Javier Zaidman, Ngai Wah Cheung, Carolyn Droste, Ian Fraser, David Johnson, Peak Mann Mah, Kathy Nicholls, David Packham, Joseph Proietto, Anthony Roberts, Simon Roger, Venessa Tsang, Roberto Abrão Raduan, Fernando Augusto Alves da Costa, Celso Amodeo, Luiz Alberto Andreotti Turatti, Rachel Bregman, Fernanda Cristina Camelo Sanches, Luis Henrique Canani, Antônio Roberto Chacra, João Lindolfo Cunha Borges, Sérgio Alberto Cunha Vêncio, Roberto Jorge da Silva Franco, Domingos d’Avila, Evandro de Souza Portes, Pedro de Souza, Luciane Mônica Deboni, Fadlo Fraige Filho, Bruno Geloneze Neto, Marcus Gomes, Suely Keiko Kohara, Elizete Keitel, Jose Francisco Kerr Saraiva, Hugo Roberto Kurtz Lisboa, Fabiana Loss de Carvalho Contieri, Rosângela Milagres, Renan Montenegro Junior, Claudia Moreira de Brito, Miguel Nasser Hissa, Ângela Regina Nazario Sabbag, Irene Noronha, Daniel Panarotto, Roberto Pecoits Filho, Márcio Antônio Pereira, Wladmir Saporito, Antonio Scafuto Scotton, Tiago Schuch, Roberto Simões de Almeida, Cássio Slompo Ramos, João Soares Felício, Fernando Thomé, Jean Carlo Tibes Hachmann, Sérgio Yamada, Cesar Yoiti Hayashida, Tarissa Beatrice Zanata Petry, Maria Teresa Zanella, Viktoria Andreeva, Angelina Angelova, Stefan Dimitrov, Veselka Genadieva, Gabriela Genova-Hristova, Kiril Hristozov, Zdravko Kamenov, Atanas Koundurdjiev, Lachezar Lozanov, Viktor Margaritov, Boyan Nonchev, Rangel Rangelov, Alexander Shinkov, Margarita Temelkova, Ekaterina Velichkova, Andrian Yakov, Naresh Aggarwal, Ronnie Aronson, Harpreet Bajaj, Guy Chouinard, James Conway, Serge Cournoyer, Gerald DaRoza, Sacha De Serres, François Dubé, Ronald Goldenberg, Anil Gupta, Milan Gupta, Sam Henein, Hasnain Khandwala, Lawrence Leiter, François Madore, Alan McMahon, Norman Muirhead, Vincent Pichette, Remi Rabasa-Lhoret, Andrew Steele, Navdeep Tangri, Ali Torshizi, Vincent Woo, Nadia Zalunardo, María Alicia Fernández Montenegro, Juan Gonzalo Godoy Jorquera, Marcelo Medina Fariña, Victor Saavedra Gajardo, Margarita Vejar, Nan Chen, Qinkai Chen, Shenglian Gan, Yaozhong Kong, Detian Li, Wenge Li, Xuemei Li, Hongli Lin, Jian Liu, Weiping Lu, Hong Mao, Yan Ren, Weihong Song, Jiao Sun, Lin Sun, Ping Tu, Guixia Wang, Jinkui Yang, Aiping Yin, Xueqing Yu, Minghui Zhao, Hongguang Zheng, Jose Luis Accini Mendoza, Edgar Arcos, Jorge Avendano, Jorge Ernesto Andres Diaz Ruiz, Luis Hernando Garcia Ortiz, Alexander Gonzalez, Eric Hernandez Triana, Juan Diego Higuera, Natalia Malaver, Dora Inés Molina de Salazar, Ricardo Rosero, Monica Alexandra Terront Lozano, Luis Valderrama Cometa, Alex Valenzuela, Ruben Dario Vargas Alonso, Ivan Villegas, Hernan Yupanqui, Dagmar Bartaskova, Petr Barton, Jana Belobradkova, Lenka Dohnalova, Tomas Drasnar, Richard Ferkl, Katarina Halciakova, Vera Klokocnikova, Richard Kovar, Jiri Lastuvka, Martin Lukac, Satu Pesickova, Karel Peterka, Jiri Pumprla, Ivan Rychlik, Frantisek Saudek, Vladimir Tesar, Martin Valis, Pavel Weiner, Stanislav Zemek, Eric Alamartine, Sophie Borot, Bertrand Cariou, Bertrand Dussol, Jean-Pierre Fauvel, Pierre Gourdy, Alexandre Klein, Yannick Le Meur, Alfred Penfornis, Ronan Roussel, Pierre-Jean Saulnier, Eric Thervet, Philippe Zaoui, Volker Burst, Markus Faghih, Grit Faulmann, Hermann Haller, Reinhold Jerwan-Keim, Stephan Maxeiner, Björn Paschen, Georg Plassmann, Ludger Rose, Ronaldo Arturo Gonzalez Orellana, Franklin Paul Haase, Juan Pablo Moreira Diaz, Luis Alberto Ramirez Roca, Jose Antonio Sánchez Arenales, José Vicente Sanchez Polo, Erick Turcios Juarez, Gyongyi Csecsei, Botond Csiky, Peter Danos, Laszlo Deak, Mihaly Dudas, Eleonora Harcsa, Katalin Keltai, Sandor Keresztesi, Krisztian Kiss, Laszlo Konyves, Lajos Major, Margit Mileder, Marta Molnar, Janos Mucsi, Tamas Oroszlan, Ivan Ory, Gyorgy Paragh, Eva Peterfai, Gizella Petro, Katalin Revesz, Robert Takacs, Sandor Vangel, Szilard Vasas, Marianna Zsom, Oomman Abraham, Raju Sree Bhushan, Dewan Deepak, Fernando M. Edwin, Natarajan Gopalakrishnan, Noble Gracious, Alva Hansraj, Dinesh Jain, C.B. Keshavamurthy, Dinesh Khullar, Sahay Manisha, Jayameena Peringat, Narayan Prasad, Rao K. Satyanarayana, Reddy Sreedhar, Melemadathil Sreelatha, Bhimavarapu Sudhakar, Ramesh Chandra Vyasam, Riccardo Bonadonna, Pietro Castellino, Antonio Ceriello, Luca Chiovato, Salvatore De Cosmo, Giuseppe Derosa, Alberto Di Carlo, Graziano Di Cianni, Giovanni Frascà, Giorgio Fuiano, Giovanni Gambaro, Giacomo Garibotto, Carlo Giorda, Fabio Malberti, Marcora Mandreoli, Edoardo Mannucci, Emanuela Orsi, Piermarco Piatti, Domenico Santoro, Ferdinando Carlo Sasso, Gaetano Serviddio, Andrea Stella, Roberto Trevisan, Anna Maria Veronelli, Luca Zanoli, Hitoshi Akiyama, Hiromi Aoki, Akimichi Asano, Tadashi Iitsuka, Shizuo Kajiyama, Susumu Kashine, Toshio Kawada, Takamoto Kodera, Hiroshi Kono, Kazunori Koyama, Yasuro Kumeda, Shozo Miyauchi, Kazuyuki Mizuyama, Tetsuji Niiya, Hiroko Oishi, Satoshi Ota, Terue Sakakibara, Masahiko Takai, Osamu Tomonaga, Mitsuru Tsujimoto, Masakiyo Wakasugi, Yasushi Wakida, Takayuki Watanabe, Masayo Yamada, Kazuhiro Yanagida, Toshihiko Yanase, Wataru Yumita, Egle Gaupsiene, Dalia Kozloviene, Antanas Navickas, Egle Urbanaviciene, Rohana Abdul Ghani, Khalid Abdul Kadir, Norsiah Ali, Mohd Daud Che Yusof, Chye Lee Gan, Mastura Ismail, Wei Yen Kong, Swee Win Lam, Li Yuan Lee, Chek Loong Loh, Anita Bhajan Manocha, Kee Sing Ng, Nik Nur Fatnoon Nik Ahmad, Vanassa Ratnasingam, Saiful Shahrizal Bin Shudim, Paranthaman Vengadasalam, Luis David Abraira Munoz, Melchor Alpizar Salazar, Juan Baas Cruz, Mario Burgos Soto, Jose Chevaile Ramos, Alfredo Chew Wong, Jose Ricardo Correa Rotter, Tonatiu Diaz Escalante, Favio Edmundo Enriquez Sosa, Fernando Flores Lozano, Luis Fernando Flota Cervera, Paul Frenk Baron, Cecilia Garcia Ballesteros, Jose David Gomez Rangel, Luis Enrique Herrera Jimenez, Sergio Saul Irizar Santana, Fernando Jimenez Flores, Hugo Laviada Molina, Rosa Isela Luna Ceballos, Belia Martin del Campo Blanco, Guadalupe Morales Franco, Oscar Tarsicio Moreno Loza, Cynthia Mustieles Rocha, Gregorio Obrador Vera, Ricardo Orozco Castellanos, Juan Peralta Calcaneo, Miguel Angel Reyes Rosano, Hiromi Rodriguez Pattzi, Juan Rosas Guzman, Isabel Erika Rucker Joerg, Sandra Berenice Saavedra Sanchez, Jose Hector Sanchez Mijangos, Pablo Serrano Sanson, Juan Alfredo Tamayo y Orozco, Eloisa Tellez Chavez, Alejandro Valdes Cepeda, Luis Venegas Carrillo, Juan Villagordoa Mesa, Rolando Zamarripa Escobedo, John Baker, Paul Noonan, Russell Scott, Robert Walker, Edward Watson, Michael Williams, Simon Young, Zaynab Abejuela, Jeimeen Agra, Grace Aquitania, Clodoaido Caringal, Rhea Severina Comia, Lalaine Delos Santos, Olivert Gomez, Cecilia Jimeno, Gerry Tan, Marsha Tolentino, Christy Yao, Yvette Ethel Yap, Ma. Dovie Lallaine Ygpuara, Renata Bijata-Bronisz, Lucyna Hotlos, Andrzej Januszewicz, Barbara Kaczmarek, Anna Kaminska, Lech Lazuka, Andrzej Madej, Stanislaw Mazur, Dorota Mlodawska-Choluj, Michal Nowicki, Grazyna Orlowska-Kowalik, Grazyna Popenda, Barbara Rewerska, Dariusz Sowinski, Liliana Monica Angelescu, Veronica Anghel, Rodica-Ioana Avram, Mihaela-Magdalena Busegeanu, Adriana Cif, Dana Cosma, Carmen Crisan, Luiza Despina Demian, Ioana Emilia Ferariu, Ildiko Halmagyi, Nicolae Hancu, Mircea Munteanu, Doru Negru, Adriana Gabriela Onaca, Ligia Petrica, Amorin Remus Popa, Aurelian-Emil Ranetti, Cristian Serafinceanu, Cristina Toarba, Alina Agafyina, Olga Barbarash, Olga Barysheva, Daniil Chizhov, Vladimir Dobronravov, Irina Glinkina, Elena Grineva, Vladimir Khirmanov, Elena Kolmakova, Tatiana Koroleva, Liudmila Kvitkova, Viacheslav Marasaev, Ashot Mkrtumyan, Tatiana Morugova, Galina Nagibovich, Oleg Nagibovich, Sergei Nedogoda, Irina Osipova, Tatiana Raskina, Yulia Samoylova, Olga Sazonova, Minara Shamkhalova, Elena Shutemova, Yuriy Shwartz, Oleg Uriasyev, Sergey Vorobyev, Anna Zateyshchikova, Dmitry Zateyshshikov, Tatyana Zykova, Slobodan Antic, Miodrag Djordjevic, Aleksandra Kendereski, Katarina Lalic, Nebojsa Lalic, Vesna Popovic-Radinovic, Jana Babikova, Olga Benusova, Ingrid Buganova, Jan Culak, Andrej Dzupina, Jana Dzuponova, Peter Fulop, Adriana Ilavska, Emil Martinka, Zuzana Ochodnicka, Daniel Pella, Iveta Smatanova, Fayzal Ahmed, Aysha Badat, Johannes Breedt, Lawrence Distiller, Vimladhevi Govender, Ravendran Govender, Mukesh Joshi, Jaco Jurgens, Gulam Latiff, Landman Lombard, Mohamed Mookadam, Nomangesi Ngcakani, Hendrik Nortje, Helena Oosthuizen, Larisha Pillay-Ramaya, Hans Prozesky, Jeevren Reddy, Paul Rheeder, Mary Seeber, Young Min Cho, In-Kyung Jeong, Sin Gon Kim, Yeong Hoon Kim, Hyuk-Sang Kwon, Min Jeong Kwon, Byung-Wan Lee, JungEun Lee, Moon-Kyu Lee, Moon-Suk Nam, Kook-Hwan Oh, Cheol- Young Park, Sun-Hee Park, Kun Ho Yoon, Pere Alvarez Garcia, Luis Asmarats Mercadal, Clara Barrios, Fernando Cereto Castro, Secundino Cigarran Guldris, Marta Dominguez Lopez, Jesus Egido de los Rios, Gema Fernandez Fresnedo, Antonio Galan Serrano, Isabel Garcia, Francisco Javier Gonzalez Martinez, Jose Esteban Jodar Gimeno, Manuel Lopez Mendoza, Tamara Malek Marin, Cristobal Morales Portillo, Maria Antonia Munar Vila, Manuel Muñoz Torres, Javier Nieto Iglesias, Jonay Pantoja Perez, Merce Perez Vera, Jose M. Portoles Perez, María Angustias Quesada Simón, Rafael Simo Canonge, Alfonso Soto Gonzalez, Manel Terns Riera, Francisco Jose Tinahones Madueno, Mercedes Velo Plaza, Chwen-Tzuei Chang, Lee-Ming Chuang, Te-Lin Hsia, Chang-Hsun Hsieh, Chih-Ching Lin, Yung- Chuan Lu, Wayne H-H Sheu, Olga Barna, Svitlana D. Bilyk, Volodymyr Botsyurko, Iryna Dudar, Ivan Fushtey, Olga Godlevska, Oleksandr Golovchenko, Olga Gyrina, Anatoliy Kazmirchuk, Iuliia Komisarenko, Oleksii Korzh, Nonna Kravchun, Oleg Legun, Borys Mankovskyy, Liliya Martynyuk, Yuriy Mostovoy, Nataliia Pashkovska, Larysa Pererva, Tetyana Pertseva, Oleksandr Samoylov, Ivan Smirnov, Yevgeniya Svyshchenko, Halyna Tomashkevych, Ivan Topchii, Nadiya Tryshchuk, Vira Tseluyko, Vadym Vizir, Maryna Vlasenko, Tetiana Zlova, Liliia Zub, Salah Abusnana, Mohamed Railey, Kamal Abouglila, Paul Ainsworth, Zishan Ali, Vijayaraman Arutchelvam, Maria Barnard, Srikanth Bellary, Emyr Davies, Mark Davies, Simon Davies, Alison Dawson, Mohsen El Kossi, Patrick English, Donald Fraser, Luigi Gnudi, Anthony Gunstone, Timothy Hall, Wasim Hanif, Alan Jackson, Andrew Johnson, Franklin Joseph, Singhan Krishnan, Mick Kumwenda, Iain MacDougall, Paul Nixon, Joseph O'Hare, Sam Philip, Shenaz Ramtoola, Manish Saxena, Davesh Sennik, Godwin Simon, Baldev Singh, Jeffrey Stephens, Anna Strzelecka, Rehan Symonds, Wayne Turner, Mona Wahba, John Wakeling, David Wheeler, Peter Winocour, Joseph Abdallah, Raied Abdullah, Matthew Abramowitz, Idalia Acosta, Joseph Aiello, Laura Akright, Ayim Akyea-Djamson, Rajendran Alappan, Radica Alicic, Amer Al-Karadsheh, Dale Crawford Allison, Carlos Arauz-Pacheco, Shahabul Arfeen, Ahmed Arif, Moogali Arvind, Naveen Atray, Ahmed Awad, Peggy Barnhill, Elizabeth Barranco, Carlos Barrera, Matthew Beacom, Venkata Behara, Diogo Belo, Rhonda Bentley-Lewis, Ramon Berenguer, Lidia Bermudez, Marializa Bernardo, Mihaela Biscoveanu, Cynthia Bowman-Stroud, Donald Brandon, Osvaldo Brusco, Robert Busch, Yamil Canaan, Alicia Chilito, Tom Christensen, Cynthia Christiano, Elena Christofides, Caroucel Chuateco, Kenneth Cohen, Robert Cohen, Debbie Cohen-Stein, Charles Cook, Daniel Coyne, Nizar Daboul, Riad Darwish, Adarsh Daswani, Kenneth Deck, Cyrus Desouza, Devasmita Dev, Monika Dhillon, Sohan Dua, Frank Eder, Ana Maria Elosegui, Mohamed El-Shahawy, John Ervin, Alberto Esquenazi, John Evans, Steven Fishbane, Juan Frias, Eugenia Galindo-Ramos, Claude Galphin, Adline Ghazi, Enrique Gonzalez, David Gorson, Anupama Gowda, Barbara Greco, Stephen Grubb, Rakesh Gulati, Jamal Hammoud, Stuart Handelsman, Israel Hartman, Kenneth Hershon, Daniel Hiser, George Hon, Radu Jacob, Maria Jaime, Aamir Jamal, Charles Kaupke, Gerald Keightley, Elizabeth Kern, Rakhi Khanna, Zeid Khitan, Sun Kim, Nelson Kopyt, Csaba Kovesdy, Gopal Krishna, Jeffrey (Jay) Kropp, Amrendra Kumar, Jayant Kumar, Neil Kumar, Jorge Kusnir, Wendy Lane, Mary Lawrence, Lawrence Lehrner, John Lentz, Dennis Levinson, Derek Lewis, Kenneth Liss, Andreas Maddux, Hiralal Maheshwari, Sreedhar Mandayam, Isam Marar, Bhasker Mehta, John Middleton, Jorge Mordujovich, Ramon Moreda, Moustafa Moustafa, Samuel Mujica Trenche, Mohanram Narayanan, Javier Narvarte, Tareq Nassar, George Newman, Brian Nichol, Philip Nicol, Josier Nisnisan, A. Kaldun Nossuli, Chamberlain Obialo, Sarah Olelewe, Michael Oliver, Andrew O'Shaughnessy, John Padron, Rohit Pankhaniya, Reginald Parker, Devesh Patel, Gnyandev Patel, Nina Patel, Humberto Pavon, Armando Perez, Carlos Perez, Alan Perlman, Karlton Pettis, Walter Pharr, Andrea Phillips, Raman Purighalla, Luis Quesada-Suarez, Rajiv Ranjan, Sanjeev Rastogi, Jakkidi Reddy, Marc Rendell, Lisa Rich, Michael Robinson, Hector Rodriguez, Sylvia Rosas, Fadi Saba, Rallabhandi Sankaram, Ravi Sarin, Robert Schreiman, David Scott, Mohamed Sekkarie, John Sensenbrenner, Muhammad Shakeel, Michael Shanik, Sylvia Shaw, Stephen Smith, Richard Solomon, Amy Sprague, Leslie Spry, Pusadee Suchinda, Senan Sultan, Prasanth Surampudi, Sherry Sussman, Anjanette Tan, Antonio Terrelonge, Michael Thompson, Fernando Trespalacios, Bruce Trippe, Pilar Trueba, Marcel Twahirwa, John Updegrove, Peter Van Buren, Mark Vannorsdall, Freemu Varghese, Pedro Velasquez-Mieyer, Sailaja Ventrapragada, Goga Vukotic, Khurram Wadud, Mark Warren, Henry Watson, Ronald Watts, Daniel Weiner, James Welker, Jean Welsh, Shelley Williams, and Michelle Zaniewski-Singh
Subjects: age, diabetes, Nephrology, kidney outcomes, sex, Diabetic kidney disease, canagliflozin, cardiovascular outcomes, chronic kidney disease, sodium/glucose cotransporter 2 inhibitors
Abstract: Rationale & Objective: It is unclear whether the effect of canagliflozin on adverse kidney and cardiovascular events in those with diabetic kidney disease varies by age and sex. We assessed the effects of canagliflozin among age group categories and between sexes in the Canagliflozin and Renal Endpoints in Diabetes with Established Nephropathy Clinical Evaluation (CREDENCE) study.Study Design: Secondary analysis of a randomized controlled trial.Setting & Participants: Participants in the CREDENCE trial.Intervention: Participants were randomly assigned to receive canagliflozin 100 mg/d or placebo.Outcomes: Primary composite outcome of kidney failure, doubling of serum creatinine concentration, or death due to kidney or cardiovascular disease. Prespecified secondary and safety outcomes were also analyzed. Outcomes were evaluated by age at baseline (Results: The mean age of the cohort was 63.0 ± 9.2 years, and 34% were female. Older age and female sex were independently associated with a lower risk of the composite of adverse kidney outcomes. There was no evidence that the effect of canagliflozin on the primary outcome (a composite of kidney failure, a doubling of serum creatinine concentration, or death from kidney or cardiovascular causes) differed between age groups (HRs, 0.67 [95% CI, 0.52-0.87], 0.63 [0.48-0.82], and 0.89 [0.61-1.29] for ages Limitations: This was a post hoc analysis with multiple comparisons.Conclusions: Canagliflozin consistently reduced the relative risk of kidney events in people with diabetic kidney disease in both sexes and across age subgroups. As a result of greater background risk, the absolute reduction in adverse kidney outcomes was greater in younger participants.Funding: This post hoc analysis of the CREDENCE trial was not funded. The CREDENCE study was sponsored by Janssen Research and Development and was conducted collaboratively by the sponsor, an academic-led steering committee, and an academic research organization, George Clinical.Trial Registration: The original CREDENCE trial was registered at ClinicalTrials.gov with study number NCT02065791.
Published: 2023

13. Stress promotes the infiltration of peripheral immune cells to the brain

Author: Eva M. Medina-Rodriguez, Dongmei Han, Jeffrey Lowell, and Eléonore Beurel
Subjects: Behavioral Neuroscience, Endocrine and Autonomic Systems, Immunology
Published: 2023

14. Shockwave Therapy in Veterinary Rehabilitation

Author: Carolina Medina
Subjects: Small Animals
Published: 2023

15. False ST-segment elevation by artifact due to an infusion pump

Author: Juan C. Garcia-Rubira, Isabel Sanchez-Medina, Jose A. Rodríguez-Velazquez, and Rafael Hidalgo-Urbano
Subjects: Cardiology and Cardiovascular Medicine
Published: 2023

16. Safety of benzodiazepines in patients with acute heart failure: A propensity score-matching study

Author: Prado Salamanca-Bautista, Miriam Romero-Correa, Francesc Formiga, Isabel Antequera-Martín-Portugués, Pau Llàcer, Iván Gabriel Marrero-Medina, Patricia Calderón-Jiménez, Miguel Ángel Moreno-Palanco, Arola Armengou-Arxe, Sonia Gonzalo-Pascua, Patricia Piñeiro-Parga, and Óscar Aramburu-Bodas
Subjects: Cardiology and Cardiovascular Medicine
Published: 2023

17. Case-controlled field study of the ICD-11 clinical descriptions and diagnostic requirements for Bodily Distress Disorders

Author: Jared Keeley, Geoffrey M. Reed, Tahilia Rebello, Julia Brechbiel, Jose Angel Garcia-Pacheco, Kazeem Adebayo, Oluyomi Esan, Oluyinka Majekodunmi, Akin Ojagbemi, Lucky Onofa, Rebeca Robles, Chihiro Matsumoto, Maria Elena Medina-Mora, Cary S. Kogan, Maya Kulygina, Wolfgang Gaebel, Min Zhao, Michael C. Roberts, Pratap Sharan, Jose Luis Ayuso-Mateos, Brigitte Khoury, Dan J. Stein, Anne M. Lovell, Kathleen Pike, Francis Creed, and Oye Gureje
Subjects: Psychiatry and Mental health, Clinical Psychology
Published: 2023

18. Use of Telemedicine for Post-discharge Assessment of the Surgical Wound. International Cohort Study, and Systematic Review with Meta-analysis

Author: James, Glasbey, Issi, Trout, Victoria, Adeyeye, Adesoji, Ademuyiwa, Adewale, Adisa, Alisha, Bhatt, Bruce, Biccard, Peter, Brocklehurst, Jean De La Croix Allen Ingabire, Francis Moïse Dossou, Irani, Durán, Rohini, Dutta, Dhruva, Ghosh, Frank, Gyamfi, Pollyanna, Hardy, Gabriella, Hyman, Ritu, Jain, Bryar, Kadir, Stephen, Knight, Oluwaseun, Ladipo-Ajayi, Ismail, Lawani, Souliath, Lawani, Rachel, Lillywhite, Rhiannon, Macefield, Laura, Magill, Janet, Martin, Jonathan, Mathers, Kenneth, Mclean, Punam, Mistry, Rohin, Mittal, Rachel, Moore, Dion, Morton, Faustin, Ntirenganya, Emmanuel, Ofori, Rupert, Pearse, Alberto, Peón, Thomas, Pinkney, Antonio Ramos de la Medina, Tubasiime, Ronald, David, Roman, Joana, Simoes, Anita, Slade, Stephen, Tabiri, Donna, Smith, Ewen, Harrison, Aneel, Bhangu, Azmina, Verjee, Emmy, Runigamugabo, Adesoji, O Ademuyiwa, Adewale, O Adisa, Maria Lorena Aguilera, Afnan, Altamini, Philip, Alexander, Sara, W Al-Saqqa, Giuliano, Borda-Luque, Jen, Cornick, Ainhoa, Costas-Chavarri, Thomas, M Drake, Stuart, J Fergusson, J Edward Fitzgerald, C Allen Ingabire, J, Lawani, Ismaïl, Zahra, Jaffry, Hosni Khairy Salem, Chetan, Khatri, Andrew, Kirby, Anyomih Theophilus Teddy Kojo, Marie Carmela Lapitan, Richard, Lilford, Andre, L Mihaljevic, Midhun, Mohan, Alphonse Zeta Mutabazi, Dmitri, Nepogodiev, Riinu, Ots, Pata, Francesco, Tomas, Poškus, Ahmad Uzair Qureshi, Antonio Ramos-De la Medina, Sarah, Rayne, Gustavo, Recinos, Kjetil, Søreide, Catherine, A Shaw, Sebastian, Shu, Richard, Spence, Neil, Smart, Ewen, M Harrison, Maria Marta Modolo, Dushyant, Iyer, Sebastian, King, Tom, Arthur, Sayeda Nazmum Nahar, Ade, Waterman, Michael, Walsh, Arnav, Agarwal, Zani, Augusto, Mohammed, Firdouse, Tyler, Rouse, Qinyang, Liu, Juan Camilo Correa, Peep, Talving, Mengistu, Worku, Alexis, Arnaud, Vassilis, Kalles, Basant, Kumar, Sunil, Kumar, Radhian, Amandito, Roy, Quek, Luca, Ansaloni, Ahmed, Altibi, Donatas, Venskutonis, Justas, Zilinskas, Tomas, Poskus, John, Whitaker, Vanessa, Msosa, Yong Yong Tew, Alexia, Farrugia, Elaine, Borg, Zineb, Bentounsi, Tanzeela, Gala, Ibrahim, Al-Slaibi, Haya, Tahboub, Osaid, H Alser, Diego, Romani, Sebestian, Shu, Piotr, Major, Aurel, Mironescu, Matei, Bratu, Amar, Kourdouli, Aliyu, Ndajiwo, Abdulaziz, Altwijri, Mohammed Ubaid Alsaggaf, Ahmad, Gudal, Al Faifi Jubran, Sam, Seisay, Bettina, Lieske, Irene, Ortega, Jenifa, Jeyakumar, Kithsiri, J Senanayake, Omar, Abdulbagi, Yucel Cengiz Dmitri Raptis, Yuksel, Altinel, Chia, Kong, Ella, Teasdale, Gareth, Irwin, Michael, Stoddart, Rakan, Kabariti, Sukrit, Suresh, Katherine, Gash, Ragavan, Narayanan, Mayaba, Maimbo, Besmir, Grizhja, Shpetim, Ymeri, Gezim, Galiqi, Roberto, Klappenbach, Diego, Antezana, Alvaro Enrique Mendoza Beleño, Cecilia, Costa, Belen, Sanchez, Susan, Aviles, Claudio Gabriel Fermani, Rubén, Balmaceda, Santiago, Villalobos, Juan Manuel Carmona, Daniel, Hamill, Peter, Deutschmann, Simone, Sandler, Daniel, Cox, Ram, Nataraja, Claire, Sharpin, Damir, Ljuhar, Demi, Gray, Morgan, Haines, Morvarid, Ashtari, Helena, Franco, Ashrarur Rahman Mitul, Sabbir, Karim, Nowrin, F Aman, Mahnuma Mahfuz Estee, Salma, UMM-E, Joyeta, Razzaque, Tasnia Hamid Kanta, Sayeeda Aktar Tori, Shadid, Alamin, Swapnil, Roy, Shadid Al Amin, Rezaul, Karim, Muhtarima, Haque, Amreen, Faruq, Farhana, Iftekhar, Margaret, O'Shea, Greg, Padmore, Ramesh, Jonnalagadda, Andrey, Litvin, Aliaksandr, Filatau, Dzmitry, Paulouski, Maryna, Shubianok, Tatsiana, Shachykava, Dzianis, Khokha, Vladimir, Khokha, Fernande, Djivoh, Francis, Dossou, Djifid Morel Seto, Dansou Gaspard Gbessi, Bruno, Noukpozounkou, Yacoubou Imorou Souaibou, Kpèmahouton René Keke, Fred, Hodonou, Ernest Yemalin Stephane Ahounou, Thierry, Alihonou, Max, Dénakpo, Germain, Ahlonsou, Alemayehu Ginbo Bedada, Carlos, Nsengiyumva, Sandrine, Kwizera, Venerand, Barendegere, Philip, Choi, Simon, Stock, Luai, Jamal, Georges, Azzie, Sameer, Kushwaha, Tzu-Ling, Chen, Chingwan, Yip, Irene, Montes, Felipe, Zapata, Sebastian, Sierra, Maria Isabel Villegas Lanau, Maria Clara Mendoza Arango, Ivan Mendoza Restrepo, Ruben Santiago Restrepo Giraldo, Edgar, Domini, Robert, Karlo, Jakov, Mihanovic, Mohamed, Youssef, Hossam, Elfeki, Waleed, Thabet, Aly, Sanad, Gehad, Tawfik, Ahmed, Zaki, Noran, Abdel-Hameed, Mohamed, Mostafa, Muhammad Fathi Waleed Omar, Ahmed, Ghanem, Emad, Abdallah, Adel, Denewar, Eman, Emara, Eman, Rashad, Ahmad, Sakr, Rehab, Elashry, Sameh, Emile, Toqa, Khafagy, Sara, Elhamouly, Arwa, Elfarargy, Amna Mamdouh Mohamed, Ghada Saied Nagy, Abeer, Esam, Eman, Elwy, Aya, Hammad, Salwa, Khallaf, Eman, Ibrahim, Ahmed, Saidbadr, Ahmed, Moustafa, Amany Eldosouky Mohammed, Mohammed, Elgheriany, Eman, Abdelmageed, Eman Abd Al Raouf, Esraa Samir Elbanby, Maha, Elmasry, Mahitab Morsy Farahat, Eman Yahya Mansor, Eman Magdy Hegazy, Esraa, Gamal, Heba, Gamal, Hend, Kandil, Doaa Maher Abdelrouf, Mohamed, Moaty, Dina, Gamal, Nada, El-Sagheer, Mohamed, Salah, Salma, Magdy, Asmaa, Salah, Ahmed, Essam, Ahmed, Ali, Mahmoud, Badawy, Sara, Ahmed, Mazed, Mohamed, Abdelrahman, Assal, Mohamed, Sleem, Mai, Ebidy, Aly Abd Elrazek, Diaaaldin, Zahran, Nourhan, Adam, Mohamed, Nazir, Adel, B Hassanein, Ahmed, Ismail, Amira, Elsawy, Rana, Mamdouh, Mohamed, Mabrouk, Lopna Ahmed Mohamed Ahmed, Mohamed Hassab Alnaby, Eman, Magdy, Manar, Abd-Elmawla, Marwan, Fahim, Bassant, Mowafy, Moustafa Ibrahim Mahmoud, Meran, Allam, Muhammad, Alkelani, Noran Halim El Gendy, Mariam Saad Aboul-Naga, Reham Alaa El-Din, Alyaa Halim Elgendy, Ismail, MOHAMED BADRELDIN MOHAMED, Mahmoud, Shalaby, Aya Adel Elsharkawy, Mahmoud Elsayed Moghazy, Khaled Hesham Elbisomy, Hend Adel Gawad Shakshouk, Mohamed Fouad Hamed, Mai Mohamed Ebidy, Mostafa, Abdelkader, Mohamed, Karkeet, Hayam, Ahmed, Israa, Adel, Mohammad Elsayed Omar, Mohamed, Ibrahim, Omar, Ghoneim, Omar, Hesham, Shimaa, Gamal, Karim, Hilal, Omar, Arafa, Sawsan Adel Awad, Menatalla, Salem, Fawzia Abdellatif Elsherif, Nourhan, Elsabbagh, Moustafa, R Aboelsoud, Ahmed Hossam Eldin Fouad Rida, Amr, Hossameldin, Ethar, Hany, Yomna Hosny Asar, Nourhan, Anwar, Mohamed, Gadelkarim, Samar, Abdelhady, Eman Mohamed Morshedy, Reham, Saad, Nourhan, Soliman, Mahmoud, Salama, Eslam, Ezzat, Arwa, Mohamed, Arwa, Ibrahim, Alaa, Fergany, Sara, Mohammed, Aya, Reda, Yomna, Allam, Hanan Adel Saad, Afnan, Abdelfatah, Aya Mohamed Fathy, Ahmed, El-Sehily, Esraa Abdalmageed Kasem, Ahmed Tarek Abdelbaset Hassan, Ahmed Rabeih Mohammed, Abdalla Gamal Saad, Yasmin, Elfouly, Nesma, Elfouly, Arij, Ibrahim, Amr, Hassaan, Mohammed Mustafa Mohammed, Ghada, Elhoseny, Mohamed, Magdy, Esraa Abd Elkhalek, Yehia, Zakaria, Tarek, Ezzat, Ali Abo El Dahab, Mohamed, Kelany, Sara, Arafa, Osama Mokhtar Mohamed Hassan, Nermin Mohamed Badwi, Ahmad Saber Sleem, Hussien, Ahmed, Kholoud, Abdelbadeai, Mohamed Abozed Abdullah, Muhammad Amsyar Auni Lokman, Suraya, Bahar, Anan Rady Abdelazeam, Abdelrahman, Adelshone, Muhammad Bin Hasnan, Athirah, Zulkifli, Siti Nur Alia Kamarulzamil, Abdelaziz, Elhendawy, Aliang, Latif, Ahmad Bin Adnan, Shahadatul, Shaharuddin, Aminah Hanum Haji Abdul Majid, Mahmoud, Amreia, Dina, Al-Marakby, Mahmoud, Salma, Mohamad Jeffrey Bin Ismail, Elissa Rifhan Mohd Basir, Citra Dewi Mohd Ali, Aya Yehia Ata, Maha, Nasr, Asmaa, Rezq, Ahmed, Sheta, Sherif, Tariq, Abd Elkhalek Sallam, Abdelrhman Kz Darwish, Sohaila, Elmihy, Shady, Elhadry, Farag, MAZEN MOHAMED AHMED HASSAN, Haidar, Hajeh, Abdelaziz, Abdelaal, Amro, Aglan, Ahmed, Zohair, Mahitab, Essam, Omar, Moussa, Esraa, El-Gizawy, Mostafa, Samy, Safia, Ali, Esraa, Elhalawany, Ahmed, Ata, Mohamed El Halawany, Mohamed, Nashat, Samar, Soliman, Alaa, Elazab, Mostada, Samy, Mohamed, A Abdelaziz, Khaled, Ibrahim, Ammar, Gado, Usama, Hantour, Esraa Alm Eldeen, Mohamed Reda Loaloa, Arwa, Abouzaid, Mostafa Ahmed Bahaa Eldin, Eman, Hashad, Fathy, Sroor, Doaa, Gamil, Eman Mahmoud Abdulhakeem, Mahmoud, Zakaria, Fawzy, Mohamed, Marwan, Abubakr, Elsayed, Ali, Hesham, Magdy, Menna Tallah Ramadan, ABDELATY MOHAMED AHMED, Neama, Salma, Mansour, Hager Abdul Aziz Amin, Ahmed Rabie Mohamed, Mahmoud, Saami, Nada Ahmed Reda Elsayed, Adham, Tarek, Sabry Mohy Eldeen Mahmoud, Islam Magdy El Sayed, Amira, Reda, Martina Yusuf Shawky, Mohammed Mousa Salem, Shahinaz Alaa El-Din, Noha Abdullah Soliman, Muhammed, Talaat, Shahinaz, Alaael-Dein, Ahmed Abd Elmoen Elhusseiny, Noha, Abdullah, Mohammed, Elshaar, Aya AbdelFatah Ibraheem, Hager, Abdulaziz, Mohammed Kamal Ismail, Mona Hamdy Madkor, Mohamed, Abdelaty, Sara Mahmoud Abdel-Kader, Osama Mohamed Salah, Mahmoud, Eldafrawy, Ahmed Zaki Eldeeb, Mostafa Mahmoud Eid, Attia, Attia, Khalid Salah El-Dien, Ayman, Shwky, Mohamed Adel Badenjki, Soliman, Abdelrahman, Samaa Mahmoud Al Attar, Farrag, Sayed, Fahd Abdel Sabour, Mohammed, G Azizeldine, Muhammad, Shawqi, Abdullah, Hashim, Ahmed, Aamer, Ahmed Mahmoud Abdelraouf, Mahmoud, Abdelshakour, Amal, Ibrahim, Basma, Mahmoud, Mohamed Ali Mahmoud, Mostafa, Qenawy, Ahmed, M Rashed, Ahmed, Dahy, Marwa, Sayed, Ahmed, W Shamsedine, Bakeer, Mohamed, Ahmad, Hasan, Mahmoud, M Saad, Khalil Abdul Bassit, Nadia Khalid Abd El-Latif, Nada, Elzahed, Ahmed El Kashash, Nada Mohamed Bekhet, Sarah, Hafez, Ahmed, Gad, Mahmoud Elkhadragy Maher, Ahmed Abd Elsameea, Mohamed, Hafez, Ahmad, Sabe, Ataa, Ahmed, Ahmed, Shahine, Khaled, Dawood, Shireen, Gaafar, Reem, Husseiny, Omnia, Aboelmagd, Ahmed, Soliman, Nourhan, Mesbah, Hossam, Emadeldin, Amgad Al Meligy, Amira Hassan Bekhet, Doaa, Hasan, Khaled, Alhady, Ahmad Khaled Sabe, Mahmoud, A Elnajjar, Majed, Aboelella, Ward, Hamsho, Ihab, Hassan, Hala, Saad, Galaleldin, Abdelazim, Hend, Mahmoud, Noha, Wael, Ahmedali, M Kandil, Ahmed, Magdy, Shimaa Said Elkholy, Badr Eldin Adel, Kareem, Dabbour, Saged, Elsherbiney, Omar, Mattar, Abdulshafi Khaled Abdrabou, Mohammed Yahia Mohamed Aly, Abdelrahman, Geuoshy, Ahmedglal, Elnagar, Saraibrahim, Ahmed, Ibrahem, Abdelmotaleb, Amr Ahmed Saleh, Manar, Saeed, Shady, Mahmoud, Badreldin Adel Tawfik, Samar Adel Ismail, Esraay, Zakaria, Mariam, O Gad, Mohamed Salah Elhelbawy, Monica, Bassem, Noha, Maraie, Nourhan Medhat Elhadary, Nourhan, Semeda, Shaza Rabie Mohamed, Hesham Mohammed Bakry, Dina Tarek Essam, Khlood, Ashour, Alaa, Elhadad, Abdulrahman, Abdel-Aty, Ibrahim, Rakha, Sara Mamdouh Matter, Rasha, Abdelhamed, Omar, Abdelkader, Ayat, Hassaan, Yasmin, Soliman, Amna, Mohamed, Sara, Ghanem, Sara Amr Mohamed Farouk, Eman Mohamed Ibrahim, Esraa, El-Taher, Merna, Mostafa, Mohamed Fawzy Mahrous Badr, Rofida, Elsemelawy, Aya, El-Sawy, Ahmad, Bakr, Ahmad Abdel Razaq Al Rafati, Sten, Saar, Arvo, Reinsoo, Nebyou, Seyoum, Tewodros, Worku, Agazi, Fitsum, Matti, Tolonen, Ari, Leppäniemi, Ville, Sallinen, Benoît, Parmentier, Matthieu, Peycelon, Sabine, Irtan, Sabrina, Dardenne, Elsa, Robert, Betty, Maillot, Etienne, Courboin, Alexis Pierre Arnaud, Juliette, Hascoet, Olivier, Abbo, Amir Ait Kaci, Thomas, Prudhomme, Quentin, Ballouhey, Céline, Grosos, Laurent, Fourcade, Tolg, Cecilia, Colombani, Jean-Francois, Francois-Coridon, Helene, Xavier, 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Emmanuel, Akatibo, Musah, Yakubu, Hope Edem Kofi Kordorwu, Kwasi, Asare-Bediako, Enoch, Tackie, Kenneth, Aaniana, Emmanuel, Acquah, Richard, Opoku-Agyeman, Anthony, Avoka, Kwasi, Kusi, Kwame, Maison, Frank Enoch Gyamfi, Gandau Naa Barnabas, Saiba, Abdul-Latif, Philip Taah Amoako, Anthony, Davor, Victor, Dassah, Prince Kwakyeafriyie Dagoe, Elliot, Akoto, Eric, Ackom, Ekow, Mensah, Ebenezer Takyi Atkins, Christian Lari Coompson, Nikolaos, Ivros, Christoforos, Ferousis, Vasileios, Kalles, Christos, Agalianos, Ioannis, Kyriazanos, Christos, Barkolias, Angelos, Tselos, Georgios, Tzikos, Evangelos, Voulgaris, Dimitrios, Lytras, Athanasia, Bamicha, Kyriakos, Psarianos, Anastasios, Stefanopoulos, Ioannis, Patoulias, Dimitrios, Sfougaris, Ioannis, Valioulis, Dimitrios, Balalis, Dimitrios, Korkolis, Dimitrios, K Manatakis, Georgios, Kyrou, Georgios, Karabelias, Iason-Antonios, Papaskarlatos, Kolonia, Konstantina, Nikolaos, Zampitis, Stylianos, Germanos, Aspasia, Papailia, Theodosios, 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Adella, Anthonius Santoso Rulie, Ferdy, Iskandar, Jonny, Setiawan, Cicilia Viany Evajelista, Hani, Natalie, Arlindawati, Suyadi, Rudy, Gunawan, Herlin, Karismaningtyas, Lusi Padma Sulistianingsih Mata, Ferry Fitriya Ayu Andika, Afifatun, Hasanah, T Ariani Widiastini, Nurlaila Ayu Purwaningsih, Annisa Dewi Fitriana Mukin, Dina Faizatur Rahmah, Hazmi Dwinanda Nurqistan, Hasbi Maulana Arsyad, Novia, Adhitama, Wifanto Saditya Jeo, Nathania, Sutandi, Audrey, Clarissa, Phebe Anggita Gultom, Matthew, Billy, Andreass, Haloho, Nadya, Johanna, Felix, Lee, Radin Mohd Nurrahman Radin Dorani, Martha, Glynn, Mohammad, Alherz, Wennweoi, Goh, Haaris, A Shiwani, Lorraine, Sproule, Kevin, C Conlon, Miklosh, Bala, Asaf, Kedar, Luca, Turati, Bianco, Federica, Francesca, Steccanella, Gallo, Gaetano, Mario, Trompetto, Giuseppe, Clerico, Sammarco, Giuseppe, Rosario, Sacco, Angelo, Benevento, Luisa, Giavarini, Mariano Cesare Giglio, Luigi, Bucci, Gianluca, Pagano, Viviana, Sollazzo, Roberto, Peltrini, Gaetano, Luglio, Arianna, Birindelli, Salomone Di Saverio, Gregorio, Tugnoli, Miguel Angel Paludi, Pietro, Mingrone, Domenica, Pata, Francesco, Selvaggi, Lucio, Selvaggi, Gianluca, Pellino, DI MARTINO, Natale, Gianluca, Curletti, Paolo, Aonzo, Raffaele, Galleano, Stefano, Berti, Elisa, Francone, Boni, Silvia, Lorenzon, Laura, LO CONTE, Annalisa, Balducci, Genoveffa, Gianmaria, Confalonieri, Giovanni, Pesenti, Laura, Gavagna, Giorgio, Vasquez, Simone, Targa, Savino, Occhionorelli, Dario, Andreotti, Giacomo, Pata, Andrea, Armellini, Deborah, Chiesa, Fabrizio, Aquilino, Nicola, Chetta, Arcangelo, Picciariello, Mohamed, Abdelkhalek, Andrea, Belli, Silvia De Franciscis, Annamaria, Bigaran, Alessandro, Favero, Stefano M, M Basso, Paola, Salusso, Martina, Perino, Sylvie, Mochet, Diego, Sasia, Francesco, Riente, Migliore, Marco, David, Merlini, Silvia, Basilicò, Carlo, Corbellini, Veronica, Lazzari, Yuri, Macchitella, Luigi, Bonavina, Angelieri, Daniele, Coletta, Diego, Falaschi, Federica, Catani, Marco, Reali, Claudia, Mariastella, Malavenda, DEL BASSO, Celeste, Sergio, Ribaldi, Coletti, Massimo, Natili, Andrea, Depalma, Norma, Iannone, Immacolata, Antoniozzi, Angelo, Davide, Rossi, Daniele, Gui, Gerardo, Perrotta, Matteo, Ripa, Francesco Ruben Giardino, Maurizio, Foco, Erika, Vicario, Federico, Coccolini, Gabriela Elisa Nita, Nicoletta, Leone, Andrea, Bondurri, Anna, Maffioli, Andrea, Simioni, Davide De Boni, Sandro, Pasquali, Elena, Goldin, Elena, Vendramin, Eleonora, Ciccioli, Umberto, Tedeschi, Luca, Bortolasi, Paola, Violi, Tommaso, Campagnaro, Simone, Conci, Giovanni, Lazzari, Calogero, Iacono, Alfredo, Gulielmi, Serena, Manfreda, Rinaldi, ROSA ANNA, Maria Novella Ringressi, Beatrice, Brunoni, Giuseppe, Salamone, Mirko, Mangiapane, Paolino De Marco, Antonella La Brocca, Roberta, Tutino, Vania, Silvestri, Leo, Licari, Fontana, MARIO TOMMASO, Nicolò, Falco, Gianfranco, Cocorullo, Mostafa, Shalaby, Pierpaolo, Sileri, Claudio, Arcudi, Isam, Bsisu, Khaled, Aljboor, Lana, Abusalem, Aseel, Alnusairat, Ahmad, Qaissieh, Emad, Al-Dakka, Ali, Ababneh, Oday, Halhouli, Taha, Yusufali, Hussein, Mohammed, Justus, Lando, Robert, Parker, Wairimu, Ndegwa, Mantas, Jokubauskas, Jolanta, Gribauskaite, Justas, Kuliavas, Audrius, Dulskas, Narimantas, E Samalavicius, Kristijonas, Jasaitis, Audrius, Parseliunas, Viktorija, Nevieraite, Margarita, Montrimaite, Evelina, Slapelyte, Edvinas, Dainius, Romualdas, Riauka, Zilvinas, Dambrauskas, Andrejus, Subocius, Linas, Venclauskas, Antanas, Gulbinas, Saulius, Bradulskis, Simona, Kasputyte, Deimante, Mikuckyte, Mindaugas, Kiudelis, Tomas, Jankus, Steponas, Petrikenas, Matas, Pažuskis, Zigmantas, Urniežius, Mantas, Vilčinskas, Vincas Jonas Banaitis, Vytautas, Gaižauskas, Edvard, Grisin, Povilas, Mazrimas, Rokas, Rackauskas, Mantas, Drungilas, Karolis, Lagunavicius, Vytautas, Lipnickas, Dovilè, Majauskyté, Valdemaras, Jotautas, Tomas, Abaliksta, Laimonas, Uščinas, Gintaras, Simutis, Adomas, Ladukas, Donatas, Danys, Erikas, 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S, Y Sii, Kean Leong Koay, Yi Koon Tan, Alvin Ee Zhiun Cheah, Chui Yee Wong, Tuan Nur'Azmah Tuan Mat, Crystal Yern Nee Chow, Prisca A, L Har, Yishan, Der, Fitjerald, Henry, Xinwei, Low, Ya Theng Neo, Hian Ee Heng, Shu Ning Kong, Cheewei, Gan, Yi Ting Mok, Yee Wen Tan, Kandasami, Palayan, Mahadevan Deva Tata, Yih Jeng Cheong Kuhaendran Gunaseelan, Wan Nurul 'Ain Wan Mohd Nasir, Pigeneswaren, Yoganathan, Eu Xian Lee, Jian Er Saw, Li Jing Yeang, Pei Ying Koh, Shyang Yee Lim, Shuang Yi Teo, Nicole, Grech, Daniela, Magri, Kristina, Cassar, Christine, Mizzi, Malcolm, Falzon, Nihaal, Shaikh, Ruth, Scicluna, Stefan, Zammit, Sean, Mizzi, Svetlana Doris Brincat, Thelma, Tembo, Vu Thanh Hien Le, Tara, Grima, Keith, Sammut, Kurt, Carabott, Ciskje, Zarb, Andre, Navarro, Thea, Dimech, Georgette Marie Camilleri, Isaac, Bertuello, Jeffrey, Dalli, Karl, Bonavia, Samantha, Corro-Diaz, Marisol, Manriquez-Reyes, Amina, Abdelhamid, Abdelmalek, Hrora, Sarah, Benammi, Houda, Bachri, Meryem, Abbouch, Khaoula, 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Corro-Diaz, Samantha, Manriquez-Reyes, Marisol, Abdelhamid, Amina, Hrora, Abdelmalek, Benammi, Sarah, Bachri, Houda, Abbouch, Meryem, Boukhal, Khaoula, Mammar Bennai, Redouane, Belkouchi, Abdelkader, Sobhi Jabal, Mohamed, Benyaiche, Chaymae, Vermaas, Maarten, Duinhouwer, Lucia, Pastora, Javier, Wood, Greta, Soledad Merlo, Maria, Ajao, Akinlabi, Ayandipo, Omobolaji, Lawal, Taiwo, Abdurrazzaaq, Abdussemiu, Alada, Muslimat, Nasir, Abdulrasheed, Adeniran, Jame, Habeeb, Olufemi, Popoola, Ademola, Adeyeye, Ademola, Adebanjo, Ademola, Adesanya, Opeoluwa, Adeniyi, Adewale, Mendel, Henry, Bello, Bashir, Muktar, Umar, Osinowo, Adedapo, Olagboyega Olajide, Thoma, Oshati, Oyindamola, Ihediwa, George, Adenekan, Babajide, Nwinee, Victor, Alakaloko, Felix, Elebute, Olumide, Lawal, Abdulrazzaq, Bode, Chri, Olugbemi, Mojolaoluwa, Adesina, Alaba, Faturoti, Olubukola, Odutola, Oluwatomi, Adebola, Oluwaseyi, Onuoha, Clement, Taiwo, Ogechukwu, Williams, Omolara, Balogun, Fatai, Ajai, Olalekan, Oludara, 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Amjad, Hamarshi, Aseel, And Taher, Ayman, Qawasmi, Israa, Qurie, Khalid, Altarayra, Marwa, Ghannam, Mohammad, Shaheen, Alaa, Herebat, Azher, Abdelhaq, Aram, Shalabi, Ahmad, Abu-Toyour, Maram, Asi, Fatema, Shamasneh, Ala, Atiyeh, Anwar, Mustafa, Mousa, Zaa'Treh, Rula, Dabboor, Majd, Alaloul, Ena, Baraka, Heba, Meqbil, Jehad, Al-Buhaisi, Alaa, Elshami, Mohamedraed, Afana, Samah, Jaber, Sahar, Alyacoubi, Said, Abuowda Tasneem Idress, Yousef, Abuqwaider, Eman, Al-Saqqa, Sara, Bowabsak, Alaa, El Jamassi, Alaa, Hasanain, Doaa, Al-Farram, Hadeel, Salah, Maram, Firwana, Aya, Hamdan, Marwa, Awad, Israa, Ashour, Ahmad, Elian Al Barrawi, Fayez, Al-Khatib, Ahmed, Al-Faqawi, Maha, Fares, Mohamed, Elmashala, Amjad, Adawi, Mohammad, Adawi, Ihdaa, Khreishi, Reem, Khreishi, Rose, Ghaben, Ahed, Nadeem, Najwa, Saqlain, Muhammad, Abbasy, Jibran, Rehman Alvi, Abdul, Shahzad, Noman, Faisal Bhopal, Kamran, Iftikhar, Zainab, Talha Butt, Muhammad, Asaat Ul Razi, Syed, Ahmed, Asdaq, Khan Niazi, Ali, Raza, Ibrahim, Baluch, Fatima, Raza, Ahmed, Bani-Sadar, Ahmad, Adil, Muhammad, Raza, Awai, Javaid, Mahnoor, Waqar, Muhammad, Ali Khan, Maryam, Mohsin Arshad, Mohammad, Amjad, Mohammadasim, Miguel Machain Vega, Gustavo, Torres Cardozo, Jorge, O Higgins Roche, Marcelo, Rodolfo Pertersen Servin, Gustavo, Alfredo Segovia Lohse, Helmut, Ines Páez Lopez, Larissa, Augusto Melo Cardozo, Ramón, Espinoza, Fernando, David Pérez Rojas, Angel, Sanchez, Diana, Sanchez Samaniego, Camila, Guevara Torres, Shalon, Canta Calua, Alexander, Razuri, Cesar, Ortiz, Nadia, Rodriguez, Xianelle, Carrasco, Nahilia, Saravia, Fridiz, Shibao Miyasato, Hector, Valcarcel-Saldaña, María, Esthefany Alejos Bermúdez, Ysabel, Carpio, Juan, Ruiz Panez, Walter, Angel Toribio Orbegozo, Pedro, Guzmán Dueñas, Carolina, Turpo Espinoza, Kevin, Maria Sandoval Barrantes, Ana, Armando Chungui Bravo, Jorge, Fuentes-Rivera, Lorena, Fernández, Carmen, Málaga, Bárbara, Ye, Joselyn, Velasquez, Ricardo, Salcedo, Jannin, Lucia Contreras-Vergara, Ana, Genoveva Vergara Mejia, Angelica, Soledad Gonzales Montejo, Maria, Del Carmen Escalante Salas, Marilia, Alcca Ticona, Willy, Vargas, Marvin, Christian Manrique Sila, George, Mas, Robinson, Del Pilar Paucar, Arazzelly, José Román Velásquez, Armando, Robledo-Rabanal, Alina, Alexander Zeta Solis, Ludwing, Turpo Espinoza, Kenny, Luis Hamasaki Hamaguchi, José, Samuel Florez Farfan, Erick, Alvi Madrid Barrientos, Linda, Jaime Herrera Matta, Juan, V Mora, John Jemuel, P Redota, Menold Archee, Francisco Roxas, Manuel, B Maño, Maria Jesusa, Dione Parreno-Sacdalan, Marie, Leanne Almanon, Christel, Walędziak, Maciej, Roszkowski, Rafa, Janik, Micha, Lasek, Anna, Radkowiak, Dorota, Rubinkiewicz, Mateusz, Fernandes, Cristina, Costa-Maia, Jose, Melo, Renato, Muntean, Liviu, Sandu Mironescu, Aurel, Corneliu Vida, Lucian, Popa, Mariuca, Mircea, Hogea, Vartic, Mihaela, Diaconescu, Bogdan, Razvan Bratu, Matei, Negoi, Ionut, Beuran, Mircea, Ciubotaru, Cezar, Uzabumwana, Norbert, Duhoranenayo, Dieudonne, Jovine, Elio, Zanini, Nicola, Landolfo, Giovanni, Aljiffry, Murad, Idris, Faisal, A Alghamdi, Mohammed Saleh, Maghrabi, Ashraf, Altaf, Abdulmalik, Alkaaki, Aroub, Khoja, Ahmad, Nawawi, Abrar, Turkustani, Sondo, Khalifah, Eyad, Albiety, Adel, Sahel, Sarah, Alshareef, Reham, Najjar, Mohammed, Alzahrani, Ahmed, Alghamdi, Ahmed, Alhazmi, Wedyan, Al Saied, Ghiath, Alamoudi, Mohammed, Masood Ria, Muhammed, Hassanain, Mazen, Alhassan, Basmah, Altamimi, Abdullah, Alyahya, Reem, Al Subaie, Norah, Al Bastawis, Fatema, Altamimi, Afnan, Nouh, Thamer, Khan, Roaa, Radojkovic, Milan, Jeremic, Ljiljana, Nestorovic, Milica, Hao Law, Jia, Say Kwang Tan, Keith, Choon Kiat Tan, Ryan, Kin Tan, Joel, Wen Liang Joel, Lau, Wei Chan, Xue, Qi Hui Leong, Faith, Seng Chong, Choon, Koh, Sharon, Yin Lee, Kai, Chung Lee, Kuok, Pluke, Kent, Dedekind, Britta, Nashidengo, Puyearashid, Ian Hampton, Mark, Joosten, Johanna, Sobnach, Sanju, Roodt, Liana, Sander, Anthony, Pape, Jame, Maistry, Niveshni, Ndwambi, Phumudzo, Kinandu, Kamau, Tun, Myint, Du Toit, Frederick, Ellison, Quinn, Burger, Sule, C Grobler, D, Bongani Khulu, Lawrence, Jennings, Vicky, Leusink, Astrid, Kariem, Nazmie, Gouws, Juan, Chu, Kathryn, Bougard, Heather, Noor, Fazlin, Dell, Angela, Van Straten, Stephanie, Khamajeet, Arvin, Kapenda Tshisola, Serge, Kabongo, Kalangu, Kong, Victor, Moodley, Yoshan, Anderson, Frank, Madiba, Thandinkosi, du Plooy, Flip, Hartford, Leila, Chilton, Gareth, Karjiker, Parveen, Ernest Mabitsela, Matlou, Ruth Ndlovu, Sibongile, Badicel, Maria, Jaich, Robert, Ruiz-Tovar, Jaime, Garcia-Florez, Lui, L Otero-Díez, Jorge, Ramos Pérez, Virginia, Aguado Suárez, Nuria, Minguez García, Javier, Corral Moreno, Sara, Vicenta Collado, Maria, Jiménez Carneros, Virginia, García Septiem, Javier, Gonzalez, Mariana, Picardo, Antonio, Esteban, Enrique, Ferrero, Esther, Espin-Basany, Eloy, Blanco-Colino, Ruth, Andriola, Valeria, Solar García, Lorena, Contreras, Elisa, García Bernardo, Carmen, Pagnozzi, Janet, Sanz, Sandra, Miyar de León, Alberto, Dorismé, Asnel, Rodicio, Joselui, Suarez, Aida, Stuva, Jessica, Diaz Vico, Tamara, Fernandez-Vega, Laura, Soldevila-Verdeguer, Carla, Sena-Ruiz, Fatima, Pujol-Cano, Natalia, Diaz-Jover, Paula, Maria Garcia-Perez, José, Jose Segura-Sampedro, Juan, Pineño-Flores, Cristina, Ambrona-Zafra, David, Craus-Miguel, Andrea, Jimenez-Morillas, Patricia, Mazzella, Angela, B Jayathilake, A, B Thalgaspitiya, S P, S Wijayarathna, L, N Wimalge, P M S, Ayomi Sanni, Hakeem, Okenabirhie, Ogheneochuko, Homeida, Anmar, Younis, Abobaker, Abdelbagi Omer, Omer, Abdulaziz, Mustafa, Mussad, Ali, Adam, Ali, Cengiz, Yucel, Björklund, Ida, Ahlqvist, Sandra, Thorell, Ander, Wogensen, Fredrik, Sokratous, Aresti, Breistrand, Michaela, Thorarinsdottir, Hildur, Sigurdadottir, Johanna, Nikberg, Maziar, Chabok, Abba, Hjertberg, Maria, Elbe, Peter, Saraste, Deborah, Rutkowski, Wiktor, Forlin, Louise, Niska, Karoliina, Sund, Malin, Oswald, Denni, Peros, Georgio, Bluelle, Rafael, Reinisch, Katharina, Frey, Daniel, Palma, Adrian, Aristotle Raptis, Dimitri, Zumbühl, Luciu, Zuber, Marku, Schmid, Roger, Werder, Gabriela, Nocito, Antonio, Gerosa, Alexandra, Mahanty, Silke, Werner Widmer, Luka, Müller, Julia, Gübeli, Alissa, Zuk, Grzegorz, Bilgin Gulcicek, Osman, Vartanoglu, Talar, Kose, Emin, Rustu Karahan, Servet, Can Aydin, Mehmet, Alper Sahbaz, Nuri, Halicioglu, Ilkay, Alis, Halil, Sapci, Ipek, Adıyaman, Can, Murat Pektaş, Ahmet, Bora Cengiz, Turgut, Tansoker, Ilkan, Işler, Vedatcan, Cevik, Muazzez, Mutlu, Deniz, Ozben, Volkan, Baris Ozmen, Berk, Bayram, Sefa, Yolcu, Sinem, Buse Kobal, Berna, Faruk Toto, Ömer, Cem Çakaloğlu, Haluk, Karabulut, Kagan, Mutlu, Vahit, Busra Ozkan, Bahar, Celik, Saban, Semiz, Anil, Bodur, Selim, Gül, Enisburak, Murutoglu, Busra, Yildirim, Reyyan, Emre Baki, Bahadir, Arslan, Ekin, Ulusahin, Mehmet, Guner, Ali, Walker, Nathan, Shrimanker, Nikhita, Cole, Simon, Breslin, Ryan, Srinivasan, Ravi, Elshaer, Mohamed, Hunter, Kristina, Al-Bahrani, Ahmed, Liew, Ignatiu, Grace Mairs, Nora, Rocke, Alistair, Dick, Lachlan, Qureshi, Mobeen, Chowdhury, Debkumar, Wright, Naomi, Skerritt, Clare, Kufeji, Dorothy, Ho, Adrienne, Dissanayake, Tharindra, Tennakoon, Athula, Ali, Wadah, Jane Lim, Shujing, Tan, Charlene, O'Neill, Stephen, Jones, Catrin, Nassif, Dima, Sharma, Abhishek, Warren, Oliver, White, Rebecca, Mehdi, Aia, Post, Nathan, Kalakouti, Eliana, Dashnyam, Enkhbat, Stourton, Frederick, Mykoniatis, Ioanni, Currow, Chelise, Wong, Francisca, Gupta, Ashish, Shatkar, Veeranna, Luck, Joshua, Kadiwar, Suraj, Smedley, Alexander, Wakefield, Rebecca, Herrod, Philip, Blackwell, Jame, Lund, Jonathan, Cohen, Fraser, Bandi, Ashwath, Giuliani, Stefano, Bond-Smith, Gile, Pezas, Theodore, Farhangmehr, Neda, Urbonas, Toma, Perenyei, Miklo, Ireland, Philip, Blencowe, Natalie, Bowling, Kirk, Bunting, David, Longstaff, Lydia, Keogh, Kenneth, Jeon, Hyunjin, Rafaih Iqbal, Muhammad, Khosla, Shivun, Jeffery, Anna, Perera, Jame, Aboelkassem Ibrahem, Ahmad, Alhammali, Tariq, Salama, Yahya, Oram, Shaun, Kidd, Thoma, Cullen, Fraser, Owen, Christopher, Wilson, Michael, Chiu, Seehui, Sarafilovi, Hannah, Ploski, Jennifer, Evans, Elizabeth, Abbas, Athar, Kamya, Sylvia, Ishak, Norzawani, Bisset, Carly, Andress, Cedar, Ru Chin, Ye, Patel, Priya, Evans, David, Haslegrave, Aidan, Boggon, Adam, Laurie, Kirsten, Connor, Katie, Mann, Thoma, Mansuri, Anahita, Davies, Rachel, Griffiths, Ewen, Raza Shahbaz, Aized, Eng, Calvin, Din, Farhat, L'Heveder, Ariadne, G Park, Esther H, Ravishankar, Ramanish, Mcintosh, Kirsten, Dar Yau, Jih, Chan, Luke, Mcgarvie, Susan, Tang, Lingshan, Lim, Hui, Yap, Suhhuey, Park, Jay, Herr Ng, Zhan, Mirza, Shahrukh, Lin Ang, Yun, Walls, Luke, Roy, Chloe, Paterson-Brown, Simon, Camilleri-Brennan, Julian, S D'Souza, Michelle, Pronin, Savva, Ewart Henshall, David, Zuling Ter, Eunice, Fouad, Dina, Minocha, Ashish, English, William, Morgan, Catrin, Townsend, Dominic, Maciejec, Laura, Mahdi, Shareef, Akpenyi, Onyinye, Hall, Elisabeth, Caydiid, Hanaan, Rob, Zakaria, Abbott, Tom, D Torrance, Hew, Johnston, Robin, Akil Gani, Mohammed, Gravante, Gianpiero, Rajmohan, Shivanchan, Majid, Kiran, Dindyal, Shiva, Smith, Christopher, Palliyil, Madanmohan, Patel, Sanjay, Nicholson, Luke, Harvey, Neil, Baillie, Katie, Shillito, Sam, Kershaw, Suzanne, Bamford, Rebecca, Orton, Peter, Reunis, Elke, Tyler, Robert, Cheong Soon, Wai, M Jama, Guled, Dhillon, Dharminder, Pate, Khyati, Nanthakumaran, Shayanthan, Heard, Rachel, Yan Chen, Kar, Barmayehvar, Behrad, Datta, Uttaran, K Kamarajah, Sivesh, Karandikar, Sharad, Iftekhar Tani, Sobhana, Monaghan, Eimear, Donnelly, Philippa, Walker, Michael, Parakh, Jehangirshaw, Blacker, Sarah, Kaul, Anil, Paramasivan, Arjun, Farag, Sameh, Nessa, Ashrafun, Awadallah, Salwa, Lim, Jieqi, Chean Khun Ng, Jame, P Kiran, Ravi, Murray, Alice, Etchill, Eric, Dasari, Mohini, Puyana, Juan, Haddad, Nadeem, Zielinski, Martin, Choudhry, Asad, Caliman, Celeste, Beamon, Mieshia, Duane, Therese, Swaroop, Mamta, Myers, Jonathan, Deal, Rebecca, Schadde, Erik, Hemmila, Mark, Napolitano, Lena, To, Kathleen, Makupe, Alex, Musowoya, Joseph, Van Der Naald, Niel, Kumwenda, Dayson, Reece-Smith, Alex, Otten, Kar, Verbeek, Anna, Prins, Marloe, Andres Baquero Suarez, Alibeth, Balmaceda, Ruben, Deane, Chelsea, Dijan, Emilio, Elfiky, Mahmoud, Koskenvuo, Laura, Thollot, Aurore, Limoges, Bernard, Capito, Carmen, Alexandre, Challine, Kotobi, Henri, Leroux, Julien, Pinnagoda, Kalitha, Henric, Nicola, Azzis, Olivier, Rosello, Olivier, Francois, Poddevin, Etienne, Sara, Buisson, Philippe, Hmila, Sophian, Clegg-Lamptey, Joe-Nat, Imoro, Osman, Emmanuel Abem, Owusu, Papageorgiou, Dimitrio, Soulou, Vasiliki, Asturias, Sabrina, Peña, Lenin, B O'Connor, Donal, Realis Luc, Alberto, Alessandro Russo, Alfio, Ruzzenente, Andrea, Taddei, Antonio, Cona, Camilla, Bottini, Corrado, Pascale, Giovanni, Rotunno, Giuseppe, Solaini, Leonardo, Maria Pascale, Marco, Notarnicola, Margherita, Corbellino, Mario, Sacco, Michele, Ubiali, Paolo, Cautiero, Roberto, Bocchetti, Tommaso, Muzio, Elena, Guglielmo, Vania, Morandi, Eugenio, Mao, Patrizio, De Luca, Emilia, Mahmoud Ali, Farah, Žilinskas, Justa, Strupas, Kestuti, Kondrotas, Pauliu, Baltrunas, Roberta, Kutkevicius, Juoza, Ignatavicius, Povila, Ling Tan, Choy, Yng Siaw, Jia, Young Yam, Sir, Wilson, Ling, Rezal Abdul Aziz, Mohamed, Bondin, John, Diaz Zorrilla, Carmina, Majbar, Ana, Sale, Danjuma, Abdullahi, Lawal, Osagie, Olabisi, Faboya, Omolara, Fatuga, Adedeji, Taiwo, Agboola, Nwabuoku, Emeka, Bliksøen, Marte, Ali Khan, Zain, Coronel, Jazmin, Miranda, Cesar, Vasquez, Idelso, M Helguero-Santin, Lui, Rickard, Jennifer, Adedeji, Adesina, Alqahtani, Saleh, Rath, Max, Van Niekerk, Michael, Zacharia Koto, Modise, Matos-Puig, Roel, Israelsson, Leif, Schuetz, Tobia, Arif Yuksek, Mahmut, Mericliler, Meric, Uluşahi, Mehmet, Wolf, Bernhard, Fairfield, Cameron, Liang Yong, Guo, Whitehurst, Katharine, Redgrave, Natalie, K Musyoka, Caroluce, Olivier, Jame, Lee, Kathryn, Cox, Michael, H Farhan-Alanie, Muhamed M, Callan, Rory, Chibuye, Chali, Hassanein Ahmed Ali, Tebian, Rekhis, Syrine, Rommaneh, Muna, Hao Sam, Zi, Hong Chieh Chen, Jacky, Roi, Dylan, Brunelli Pugliesi, Thay, Pardo, Gabriel, Blanco, Ruth, and Grasset Escobar, Eugenio
Subjects: surgical site infection , surgical complications , global surgery , global health , research methodology , outcome assessment, surgical wound, Surgery, telemedicine, postdischarge
Abstract: Objective: This study aimed to determine whether remote wound reviews using telemedicine can be safely upscaled, and if standardised assessment tools are needed. Summary background data: Surgical site infection is the most common complication of surgery worldwide, and frequently occurs after hospital discharge. Evidence to support implementation of telemedicine during postoperative recovery will be an essential component of pandemic recovery. Methods: The primary outcome of this study was surgical site infection reported up to 30-days after surgery (SSI), comparing rates reported using telemedicine (telephone and/or video assessment) to those with in-person review. The first part of this study analysed primary data from an international cohort study of adult patients undergoing abdominal surgery who were discharged from hospital before 30-days after surgery. The second part combined this data with the results of a systematic review to perform a meta-analysis of all available data conducted in accordance with PRIMSA guidelines (PROSPERO:192596). Results: The cohort study included 15,358 patients from 66 countries (8069 high, 4448 middle, 1744 low income). Of these, 6907 (45.0%) were followed up using telemedicine. The SSI rate reported using telemedicine was slightly lower than with in-person follow-up (13.4% vs. 11.1%, P
Published: 2023

19. Prevalencia de trastornos musculoesqueléticos en el personal de salud operativo del Hospital Básico Guaranda

Author: Karina Beatriz Barragán Aldaz, Joshua Patricio Jordán Medina, Fanny Gabriela Barragán Quishpe, and Nicole Elizabeth Jordán Medina
Abstract: La investigación denominada “Prevalencia de trastornos musculoesqueléticos en el personal de salud operativo del Hospital Básico Guaranda” tuvo como objetivo determinar la prevalencia de los trastornos musculoesqueléticos que sufren los trabajadores de salud al no contar con una ergonomía de anticipación debidamente controlada que ocasiona la presencia de la enfermedad. El enfoque mixto permitió conocer las particularidades que generan los TME, mediante la recolección de la información de forma estadística a partir de un informe analítico obtenido en la institución, en este mismo contexto metodológico se utilizó el de tipo transversal y la descriptiva para conocer los factores que influyen en el desarrollo de la enfermedad en el personal de salud, en tanto que en la población de estudio se establecieron criterios de inclusión y exclusión, lo que permitió contar con una muestra de 68 personas que formaron parte del grupo de estudio, como técnica de recolección de la información la encuesta utilizada fue el cuestionario Nórdico de Kuorinka para conocer la presencia de sintomatología musculoesquelética, lo que reflejó como resultado que la prevalencia de laenfermedad corresponde al 34.7% constituido en su gran mayoría por el personal médico que labora en diferentes áreas hospitalarias, de igual manera se determinó que la región más afectada se localizó en el cuello. Finalmente se estableció que el tiempo de molestia y aparición de síntomas musculares y esqueléticos fue de 1 a 7 días, mismo que se atribuyó a la posición ergonómica inadecuada.
Published: 2023

20. Association of Time of Day With Outcomes Among Patients Triaged for a Suspected Severe Stroke in Nonurban Catalonia

Author: Álvaro García-Tornel, Alan Flores, Mikel Terceño, Pedro Cardona, Sergi Amaro, Meritxell Gomis, Josep Zaragoza, Jerzy Krupinski, Manuel Gómez-Choco, Natalia Mas, Dolores Cocho, Esther Catena, Francesc Purroy, Matias Deck, Marta Rubiera, Jorge Pagola, David Rodriguez-Luna, Jesús Juega, Noelia Rodríguez-Villatoro, Carlos A. Molina, Cristina Soro, Xavier Jimenez, Mercè Salvat-Plana, Antoni Dávalos, Tudor G Jovin, Sonia Abilleira, Natalia Pérez de la Ossa, Marc Ribó, Estela Sanjuan, Katherine Santana, Olga Maisterra, Estevo Santamarina, Marian Muchada, Sandra Boned, Antonio Palasi Franco, Marta Olivé Gadea, Matías Deck, Manuel Requena, Victoria Sala, Lucía Muñoz, Mónica Millán, Elena López-Cancio, Laura Dorado, María Hernández-Pérez, Jordi Ciurans, Daniela Samaniego, Tamara Canento, Lorena Martin, Anna Planas, Joaquin Broto, Agustín Sorrentino, Martí Paré, Nuole Zhu, Alicia Garrido, Laia Grau, Ane Miren Crespo, Silvia Presas, Miriam Almendrote, Alba Ramos, Giuseppe Lucente, Lourdes Ispierto, Manuel Lozano, Juan Luis Becerra, Marta Jiménez, Dolores Vilas Rolán, Nicolas Guanyabens, Josep Sanchez-Ojanguren, Alicia Martínez-Piñeiro, Sara Forcén, Mireia Gea, Marta Álvarez, Anna Ramos, Manuel Domínguez Lizarbe, Rubio Guerra, Irene Bragado, Andrea Arbex, Luis Rodríguez, Alejandro Bustamante, Pere Cardona Portela, Helena Quesada García, Blanca Lara Rodríguez, Nuria Cayuela, Julia Miró, Clara Marzal, Andrés Paipa, Sergio Campoy, Ana Núñez, Pablo Arroyo, Sarah Besora, Vanessa Adell, Jaume Campdelacreu, Montse Alemany Martí, Belén González, Laura Bau Vila, Marta Fiter Crespo, Anna Berbel, Ma. Cristina Villaescusa Urbaneja, Núria Guillen, Nuria Vidal, Patricia Valentina Vérez Santamaria, Diego Herrero Navarro, Marta Simó, Mercedes Falip, Elisabeth Matas, Neus Mongay Ochoa, Ariadna Gifreu, Albert Muñoz, Lucía Romero, Eduard Portell, Guillermo Hernández Perez, F. Ruiz Esteve, Silvia Teixidor, Augusto Salazar Talavera, Roser Gómez, Xabier Urra Nuin, Martha Vargas, Ángel Chamorro, Laura Llull, Arturo Renú, Salvatore Rudilosso, Raquel Sánchez del Valle, Helena Ariño, Nuria Solà, Delón la Puma, Francisco Gil, Juan Bernardo Gómez, Nuria Matos, Neus Falgàs, Sergi Borrego, Almudena Sánchez, Mircea Balasa, Carmen Montejo, Mar Guasp, David Reyes, Pablo Sánchez Cervilla, Jose Miguel Contador, Victor Augusto Vera Monge, Oscar Ramos, Alejandro Rodríguez, Ana Rodríguez Campello, Gemma Romeral Ballester, Mireia Llop Trujillano, Eva Giralt Steinhauer, Elisa Cuadrado Godia, Angel Javier Ois Santiago, Jordi Jimenez Conde, Joan Martí Fábregas, Daniel Guisado, Luís Prats, Pol Camps, Raquel Delgado, Alejandro Martínez Domeño, Rebeca Marín, David Cànovas, Jordi Estela, Marta Ros, Sonsoles Aranceta, Jordi Espinosa, Marta Rubio, Cristina Lafuente, Oriol Barrachina, Alicia Anguita, Anna Reverter, Carmen García, Gemma Sansa, Mariona Hervas, Monica Crosas, Tania Delgado, Dra Sonia Huertas Folch, Gemma Muñoz Gamito, Josep Trenado Alvarez, Teresa Subirana, Jessica Molina, Laura Comes Romero, Gemma Guardia Valls, Miriam Jover, Javier Joaquín Sotova, Sonia Mª García Sánchez, Sebastian Valenzuela, Juan José Mengual, M. Àngels Font, Mª Isabel Gómez Ruiz, Irati Zubizarreta, Susana Fernández González, Laura Gubieras, Carmen E. Cobos, Luis Mena Romo, Nuria Caballol, Luis Cano, Joaquín Serena Leal, Yolanda Silva Blas, Irene Bragado Trigo, Saima Bashir Viturro, Laura Pardo Albiñana, Montserrat Reina Garrido, Carla Marco Cazcarra, Karol Enrique Uscamaita, Fabian Márquez, Cristina Coll, Mar Irida Lloret Villlas, Berta Solano Vila, Berta Alemany Perna, Daniel López Domínguezl, Mercedes de Lera, Anna Cots Foraster, Urszula Bojaryn, Ikram Benabdelhak, Gerard Mauri Capdevila, Jordi Sanahuja Montesinos, Daniel Vázquez, José Vicente Hervás, Cristina González, Alejandro Quílez, Mikel Vicente Pascual, María Ruiz, Yolanda Riba, M. Pilar Gil Villar, Cristina García, Xavier Ustrell Roig, Mònica Baldrich Mora, Anna Pellisé Guinjoan, Judit Borras, Alba Mañé Martínez, Rafael Marés, Jaume Viñas i Gaya, Laia Seró, Paula Rodríguez, Gislaine Castilho, Angela Monterde Ortega, Silvia Reverté, Joan Josep Baiges, Gisela Martín Ozaeta, Sonia Escalante, Patricia Esteve Belloch, Iago Payo, Júlia Saura Salvado, Josep M Soler Insa, Ester Tio Vilamala, Josep Abos Navarro, Héctor Cruz Tabuenca, Tamara Canento Sánchez, Elisabet Roldán, Elsa Puiggrós Rubiol, Elisabet Franquet, Lidia Fuentes, Javier Donaire, Elena Martí, Laura Giménez, Junior Gil Vázquez, Eloisa Nieto Clara Gris Ambrós, Puri Rodríguez, José Félix Oletta, Pilar Pons Mellado, Bárbara Gómez, Vergilin Raileau, Oscar Pardina, Jordi Mercadal, María López-Diéguez, Pilar Pérez, Lourdes Gabarró, María Orriols, José Carlos Molina, Joan Josep Canet, Mireia Roca, Muriel Álvaro, Francesc Boneu, Georgina Giménez, Jaume Albà, Francesc Gibert, Jéssica Garcia, Patricia Barragan, Gustavo Jurado, Vanesa Pascual_Medicina Interna, Josep Sabaté Ortega, Joan Amaurys Martínez Solano, Víctor Fernández, Mónica Torres, Ana Belén Montero Alvaredo, Laura Redondo Parejo, Josep Maria Aragonés, Anna Bullón, Cora Loste, Paula González, Neker Bejarano, Francisco Sanchez, Gianni Lucchetti, Xavier Pla, Dr Javier Gimeno, Esteban Reynaga, Montse Barcons, Gabriel Celedón, Juan Ortiz, Dr Goran Anastasovski, Dr Oscar Mascaró, Dr Javier Diez de los Ríos, Meritxell Feliu, Anna Ribera, Cristhian Ruiz, Gerard Corominas, Dra Daniella Nunes, Claudia Roca, Nadina Latorre, Lizbeth Yataco, Maricelys Cruz, Nerea Blanco, Santiago Castejón, Claustre Pont Sunyer, Jordi Espinosa Garcia, Rodrigo Paz Martin, Albert de Luis Sanchez, Dolores Espinosa Vivas, Juan Valencia Molina, Planels Palome, Laia Tomas Chaume, Ares Villagrasa Vilella, Marco Bustamante, Anunciación Boltes, Fernando Rodríguez, Itziar Arrieta, Jordi Ciurans Molist, Barnés Andreu, Ernest Palomeras Soler, Nicolau Guanyabens Buscà, Manuel Daza López, Jordi Bigas Farreres, Virginia Casado Ruiz, Desiree Muriana Batiste, Mª Pilar Sanz Cartagena, Eulalia Cabot de Vega, Josep Bassa Real, Hector Pelaez Roman, César Socolich, Josep Mª Alonso Camp, Antonio Tomás Cano Orgaz, Mª Pilar Fossas Felip, Nicolás Morón, Sandra Bacca, Mauricio Molina, Francesc Casarramona, Lorena Elias, Muhammad Zidane Bukaei, Jose Antonio Martos Gutierrez, Judith Lopez Escuin, Cristina Olaizola, Yolexis López Vargas, Juan Jiménez Oyonarte, Rashida Soultana, Eduardo Sanjurjo Golpe, Esther Salvador, Guillem Vila, Marcos Serrano, Matilde Nuria López Claverol, Marian Lamolla, Miquel Amate, Adriana Rodriguez, Ruth Romero, Montgomery del Carpio, Ana Isabel Hernandez, Julián Martín, M Carmen Rosas, Antonio Nogueroles, Sorilandy Encarnación, Augusto Robles, Jose Antonio Herrera, Roger Gavilán, Toghrol Mameghani, Gastón Araujo, M.Angeles Garrido Morales, Enric Ramon Albert Segui, Eva Fernandez Climent, Francesc Paris Pujol, Mireia Judit Garrofé Seira, Lucía Gómez Pía, Fernando Salleres Nuñez, Cristina Aguar Peñalver, Cristina Vaz Lopes, Elisenda Ribera Tasa, Carmen Repullo Vilchez, Modesto Sánchez Zambrana, Beatriu Suescun Ribas, Inés Vilà Panés, Montserrat Vila Planavila, Alicia Vaqueiro Lorenzo, Meritxell Sabartés Guixes, Jorge Medina, David Sambrano, Javi Zamarreño, Carmen Pirela, Paola Vélez, Luis Cajamarca, Honey Pérez, Yarles Martínez, Jesus Alexander Gonçalves, Carles Regordosa, Claudia Mormeneo, Laura Griu, Maria Francia Colina, Enric Farik, Dolors Carrión Duch, Carles Badenas, Oscar Bernal, Núria Agramunt, Shyrlei Morales, Victoria Reynoso, Miguel Guerrero, Primitivo Romera Cid, Mònica Folqué, Claudia Pedroza, Adnan Hachem, Íñigo Soteras Martínez, Xavier Verdera García, Mercè López Amorós, Xavier Costa Subirós, Marta Cufí Benet, Cecile Van Eendenburg, Teresa Osuna, Dra Gina Santos, Dra Mireia Pallisera, Dr Lluís Gonzalo Oliva, Dra Gemma Sanchez, Dr Xavier Basurto, Dr Ludgi Vivoda, Dr Richard Van der Kleyn, Dra Laura Robles, Ana Cabanelas Barranco, Mª Cruz Almendros, Marc Pérez Oliveras, Amelia Fernández Álvarez, Maria Rybyeva, Antoni Viñas, Maria Barcons, Joaquim Danès Alberto Tavera, Pablo Burbano, Cintie López, David Cruz, Paula Bisbe, Nora Fernández, Juan Carlos Palacio, Eduardo Fraiz, Oriol Aguiló, Rollmy Amorodjo, John Velázquez, Elena Sánchez, Jaume Español, Judit Perez de Celis, Anna Coll, Glòria Díaz, Margarida Vergés i Sala, Mª Ángels Casas Capdevila, Yosmairy Yoselin Ferrini, Aitor Gorriz, Diego-Javier Cucurell Navarro, Dulce Velásquez, Jaume Pla Soler, Josep González, Julian David Higuera, Lina Cuellar, Liza Margarita Miniello, Lluis Pujol, Sorin Cracan, Mora Vives, M Angela, Lopez Lopez, Montse Gorchs Molist, Delofeu Anna, Silvia Solà Muñoz, Ferreres Yolanda, Carol Pujalte, Elisabeth Téllez Marín, Yolanda Font Casas, Sara Hernández Luque, Joaquim Mejias Sendra, Francesca Mellado Valero, Campos Escala, Galup De Lacanal, Lopez Diaz, Castillo Paramio, Català Estopà, Español Moreda, Calafell Majo, Carballo Almeida, Castro Naval, M Elena, Cregut Ruiz, Pere Lluis, Deulofeu Font, Fabregat Sanjuan, Joan Pere, Fontquerni Gorchs, Forés Bellés, Joan Antoni, Gomez Herrera, Juan Carlos, Hijazo Prades, Itzaina Torvisco, Marti Rovira, Obiols Gonzalez, Olive Cavero, Querol Gil, M Soledad, Rico Rodriguez, Rios Sambernardo, Ropero Molina, Jose Ramon, Sanchez Valero, Santos Arevalo, Maria Jose, Soto Garcia, Maria Angeles, Tebar Escribano, Torres Garcia, Pedro José, Verdes Carrion, M Isabel, Verge Lopez, Juan Jose, Lopez Canela, M Angeles, Lucas Guarque, Morales Alvarez, Jorge Arnulfo, Morell Fornieles, Subirats Gomez, Maria Teresa, Torello Masa, Miquel, Val Lopez, Maria Mercedes, Palmero Reyes, Juan Manuel, Rodriguez Forne, Ruana Turiel, Sanchez Gonzalez, Sebastia Gornals, Abrio Rico, Albert Gual Falip, Aznar Oliveros, Brugues Perotti, Calvet Molinero, Catells Franco, Corrales Medina, Daroca Miro, Duran Marquez, Feliu Pradas, Figueras Casanova, Garcia Tortajada, Grajera Gallego, Azahara del Mar, Las Arroyo, Dulcenombre de Jesus, Laserreta Sanz, Llambrich Vidal, Monllao Corral, Morales de la Cruz, Moreno Blanco, Orejuela Orgaz, Piñana Suazo, Pons Minguillon, Rodríguez Gómez, José Carlos, Rodriguez Pereira, Sedo Porcel, Anna, Sevil Villar, Sierra Lopez, Torres Romero, Trepat Calveres, Anna, Ventura Arnella, Acera Gil, M Teresa, Biesot Vico, Castro Galea, Rosa Maria, Escorcia Chafer, Juan Antonio, Gil Faure, Hernandez Luque, Jimenez Delgado, Mallafre Gay, M. Angel, Olivares Sanzo, Pubill Fondevila, Sabate Fort, Segovia Agámez, Antonio Carlos, Turata Longaretti, Valle Hernandez, Trayner Guixens, Aguilar Valor, Aguirre Alvarez, Alastrue Naval, Alferez Baquero, Alonso Marne, Aloy Orozco, Alvarez Colino, Alvarez Peñuela, Ameller Cirilo, Maria Vanessa, Andujar Guerrero, Estefania Remedios, Auladell Sillero, Azcarate Sorbet, Basany Genesca, Benavent Barduena, Benito Tudela, Blanch Pardo, Boluda Pla, Bonilla Gonzalez, Bru Serramalera, Burnat Andreu, Caballero Calvo-Rayo, Calvo Casellas, Camps Mombiela, Cano Bresme, Carcelen Fernandez, Caro Solà, Casasas Matavacas, Castanedo Bolado, Cerdeña Cortina, Abella Jane, Laia Collado Borrego, Colom Orri, Comellas Vilanova, Conillera Sole, Cots Torres, Cuchi Estepa, Marc de Sostoa Graell, Laura del Rio Lopez, Delgado Compte, Diaz Bueno, Diaz Maneiro, Andrea Lucia, Domenech Palau, M. Carme, Duran Carasso, Pablo Javier, El Abidi, Escoda Martin, Esteve Casanovas, Fernandez Perez, Ferre Quintero, Flores Escobar, Fontcuberta Abad, Fortes del Valle, Mª Luisa, Franco Quesada, Sara Maria, Franco Romero, Gallego Francisco, Gamiz Gala, Garcia Castañeda, Garcia Rodriguez, Casajuana Gemma, Gomez Arroyo, Gomez Girbau, Gonzalez Fernandez, Gonzalez Gonzalez, Gonzalez Lopez, Gual Obeso, Guerrero Blanco, Guillemas Roca, Guillermo Eudaldo, Sebastia Hernandez, Homar Covas, Hostench Alvarez, Huerta Royo, Ibañez Barcelo, Izquiero Cruz, Jaione Urdangarin Etxetxikia, Juárez Gimenez, Khlifi Alami, Laparra Gasco, Lara Moreales, Lasaosa Medina, Maria Lourdes, Lazaro Cava, Leon Berrar, López Maturana, Lopez Ramirez, López Romero, Lorente Marco, Lorenzo Martin, Lozano Casals, Lujan Nicola, Madrid Diaz, Jose Antonio, Maria Teresa Peris Morales, Marti Clemente, Martinez Castaño, David Natanael, Martinez Gamez, Martinez Gonzalez, Martinez Quesada, Maria de la Cabeza, Marzà Fusté, Melendo Lasheras, Miralles Mestre, Montserrat Puig Pastalle, Montserrate Vidal, Mora Mellado, Morales Ponce, Morera Cabre, Morera Vivet, Mundi Souza, Muñoz Quiles, Navea Rosa, Neira Iglesias, M Asuncion, Nuñez Manrique, Mª Pilar, Obiols Martinez, Pallares Reig, Partegas Torres, Pascual Berengueras, Perez Gamez, Perez Oset, Perez Restrepo, Maria Alejandra, Planas Yeste, Planells Mangado, Puertas Carbonell, Quinteiro Blanco, Rebollar Benavente, Recasens Fernandez, Reyes Gomez, Maria del Carmen, Roca Pou, Rodriguez Ferrer, Rodriguez Franco, Rodriguez Fuertes, Rodriguez Muñoz, Rodriguez Navarro, Roig Iniesta, Romero Gracia, Rovira Brunet, Rovira de Eugenio, Rubio Baena, Ruiz Llorens, Sala Llamazares, San Juan Alaez, Sanchez Segura, Santasusana Soldevilla, Sanz Salmeron, Segura Perez, Serra Balcells, Sorina Dumitras, Teixidor Montoya, Tena Vicente, Tierno Salinas, Ester Ines, Toledo Testa, Tomàs Figueras, Tomas Ruperez, Torrano Garcia-Penche, Torres Esparza, Vazquez Blanco, Vazquez De la Paz, Vazquez Gil, Vazquez Gonzalez, Vidal Meler, Vilalta Cots, Vilches Jimenez, Visser Fernandez, Viu Gavin, Vives Vives, Carmona Jimenez, Francisco Jose, Galobardes Vilches, Gonzalez Gomez, Jodar Manzanera, Marimon Cortes, Marrodan Orive, Martin Bosch, Martorell Lopez, Millares Roca, M Jesus, Miralles Guri, Muliterno Hernandez, Muñoz Oliva, Pons Pujol, Postius Conde, Prieto Arruñada, Quintana Mathé, Rosell Mata, Alvarin Alvarez, Arrufat Flores, Bañuelos Pago, Campo Vilar, Cardus Hidalgo, Castello Gil, Maria Gloria, Castrillo Montsesinos, Clave Garces, Comes Sanroma, Descalzo Sequi, Errando Ricol, Escudero Campillo, Maria del Mar, Fernandez Alvarez, Fernandez Gomez, Franch Espinosa, Freixes Graells, Garcia Plaza, Garcia-Marron Gallego, Hernandez Simancas, Jaraba Armas, Jimenez Ramos, Lopez Oganissian, Madrona Romero, M Rosa, Martinez Millan, Martínez Morón, Merchan Encinas, Moreno Jimenez, Muñoz Rico, Navarro Rodriguez, Nogales Ibañez, Rita Maria, Novillo Viera, Parella Torrabadella, Mari Alba, Pera Villar, Carla Montserrat, Rabella Miralles, Ramis Trilles, Ribera Ortiz, Sastre Perez, Soro Borrega, Tapia Fores, Tellez Bernad, Trenado Alvarez, Felix Martin, Herrero Perez, Lanau Fuster, Lopez Gomariz, Pardo Lozano, Quintana Altimiras, Ventosa Lopez, Almodovar Damian, Alvarez Monterroso, Arambudo Comas, Boullon Garzon, Burgos Capella, Campuzano Garcia, Maria Del Mar, Capdevila Olivas, Carre Marti, Clara Isabel, Carretero Bacaicoa, Cazorla Calderon, Chacon Osuna, Cortes Planas, Cortit Olio, Delhomme Estany, Fructuos Martinez, Garcia Lopez, Pascual Luis, Genis Amill Vallve, Gonzalez Muñoz, Hernaez Ventura, Lavernia Gimenez, Martin Rojo, Martínez Medina, Mayol Barrera, Mercader Pi, Merino Dalmau, Miguel Campodarbe, Moreno Sanchez, Francisco Javier, Penela Barrameda, Prieto Ajenjo, Rodriguez Pareja, Rodríguez Piñar, Rodriguez Tello, Romero Pereda, Sainz Saborido, Santacana Martin, Santos Martinez, Sierra Chavez, Turbau Torres, Vicente Domenech, Villena Esteo, Vives Pertegaz, Baena Gonzalez, Bagaria Pont, Beltran Sanchez, Bonet Alarcon, Borch Ballescà, Buhils Clanchet, Closa Garcia, Colomina Carril, Cristina Fernandez Sanchez, Edurne Judith Fernandez Toledo, Espases Rodriguez, Espert Resa, F Xavier, Fernández Sol, Gonzalez Lugo, Gracia Llesera, Herrada Lendinez, Juliench Liesa, Sandra Alicia, Lopez Ortega, Lopez Yuste, Lozano Villanueva, Lucia Sola Soto, Madrid Castellano, Megias Cano, Daniel Jesus, Montasell Ponce, Montesinos Sospedra, Moya Martinez, Muñoz Herrera, Ocaña Fernandez, Palau Bernal, Perez Sole, Ramon Carbonell, Ribas Lop, Rubio López, Rueda Lopez, Sabat Castaño, Sabata Lara, Salmerón Ramírez, Serra Creus, Serrano Dalmau, Sumasi Mainero, Gonzalo Gabriel, Torello Masa, Valencia Primo, Ana Maria Viñuales Muñoz, Josep Roig, and Verònica Hidalgo
Subjects: Advanced and Specialized Nursing, Neurology (clinical), Cardiology and Cardiovascular Medicine
Abstract: Background: We aim to assess whether time of day modified the treatment effect in the RACECAT trial (Direct Transfer to an Endovascular Center Compared to Transfer to the Closest Stroke Center in Acute Stroke Patients With Suspected Large Vessel Occlusion Trial), a cluster-randomized trial that did not demonstrate the benefit of direct transportation to a thrombectomy-capable center versus nearest local stroke center for patients with a suspected large vessel stroke triaged in nonurban Catalonia between March 2017 and June 2020. Methods: We performed a post hoc analysis of RACECAT to evaluate if the association between initial transport routing and functional outcome differed according to trial enrollment time: daytime (8:00 am –8:59 pm ) and nighttime (9:00 pm –7:59 am ). Primary outcome was disability at 90 days, as assessed by the shift analysis on the modified Rankin Scale score, in patients with ischemic stroke. Subgroup analyses according to stroke subtype were evaluated. Results: We included 949 patients with an ischemic stroke, of whom 258 patients(27%) were enrolled during nighttime. Among patients enrolled during nighttime, direct transport to a thrombectomy-capable center was associated with lower degrees of disability at 90 days (adjusted common odds ratio [acOR], 1.620 [95% CI, 1.020–2.551]); no significant difference between trial groups was present during daytime (acOR, 0.890 [95% CI, 0.680–1.163]; P interaction =0.014). Influence of nighttime on the treatment effect was only evident in patients with large vessel occlusion(daytime, acOR 0.766 [95% CI, 0.548–1.072]; nighttime, acOR, 1.785 [95% CI, 1.024–3.112] ; P interaction P interaction >0.1 for all comparisons). We observed longer delays in alteplase administration, interhospital transfers, and mechanical thrombectomy initiation during nighttime in patients allocated to local stroke centers. Conclusions: Among patients evaluated during nighttime for a suspected acute severe stroke in non-urban areas of Catalonia, direct transport to a thrombectomy-capable center was associated with lower degrees of disability at 90 days. This association was only evident in patients with confirmed large vessel occlusion on vascular imaging. Time delays in alteplase administration and interhospital transfers might mediate the observed differences in clinical outcome. Registration: URL: https://www.clinicaltrials.gov ; Unique identifier: NCT02795962.
Published: 2023

21. Validación de un instrumento para medir el respeto de la autonomía del paciente en situación terminal durante la toma de decisiones médicas sobre el final de la vida

Author: José Isaac González-Huerta, Laura Medina-Ceja, Maria Claudia Espinel-Bermudez, Asuncion Alvarez-Del Rio, Maria de Jesus Medina-Arellano, and Irene Cordova-Jimenez
Subjects: Sociology and Political Science, Law
Abstract: Antecedentes: El respeto por la autonomía de la persona consiste en considerarlas preferencias y valores de la persona enferma durante la toma de decisions sobre el tipo de atención que recibe y es un elemento bioético-jurídico. Sin embargo, no existen instrumentos validados sobre este fenómeno que ayuden aclarificar la percepción del médico sobre este principio. Objetivo: Elaborar, validar mediante juicio de expertos y pilotear para obtener la consistencia interna de un instrumento que evalúa el nivel de acuerdo de los médicos sobre los diferentes elementos que constituyen el respeto por la autonomía de la persona enferma en etapa terminal. Métodos: Estudio transversal. Método de validación por juicio de diez expertos de México. El instrumento se piloteó en médicos de un hospital público de alta especialidad para determinar la consistencia interna del mismo. Resultados: Se generó un instrumento de 15 ítems con un índice de validez de contenido de 0.82 para 10 expertos. Fue piloteado en una muestra de 96 médicos. Se obtuvo un alfa de Cronbach de 0.694. Conclusiones: Se desarrolló, validó y evaluó la consistencia interna de un cuestionario para medir el nivel de acuerdo de médicos que atienden a persones enfermas en etapa terminal con relación a los aspectos constitutivos sobre el respeto de su autonomía. Se recomienda su aplicación en médicos para corroborar su utilidad y favorecer un diagnóstico situacional sobre la situación estudiada.
Published: 2023

22. Pharmacological efficacy of Aloe vera in wound healing: a narrative review

Author: Sandra Viviana Aparicio Salcedo, Brian Steven Carranza Aldana, Sayuri Anayca Chávez Salas, Leslie Solanth Quispe Tinco, Carlos Abel Palomino Zevallos, Ariana Nicole Peralta Medina Peralta Medina, and Juana Mónica Robles Esquerre
Subjects: General Medicine
Abstract: Aloe Vera has different therapeutic effects, including wound healing. The objective of this review is to determine the potential efficacy of the topical use of Aloe Vera in the healing of skin wounds. A bibliographic search of preclinical and clinical studies was carried out from 1999 to 2020, which included the therapeutic use of Aloe vera in the healing of: burns, surgical wounds, lactation disorders, anal fissure and anal fistula; in the databases of the VHL regional portal, PubMed and Google Scholar. It was obtained that the topical administration of Aloe vera was effective in the healing of the mentioned wounds by mainly increasing epithelization and collagen content. In conclusion, the evidence suggests that the properties and pharmacological presentation, chemical components and the effectiveness of Aloe vera to reduce the healing time of wounds make this plant a great therapeutic alternative; however, more studies are required regarding its antimicrobial property.
Published: 2023

23. Docencia en tiempos de confinamento: Un estudio exploratorio

Author: Arnoldo Llanes Medina Llanes Medina and Mabel Osnaya Moreno
Subjects: General Medicine
Abstract: El presente trabajo es un avance de investigación llevado a cabo a finales del año 2020 cuando la pandemia estaba en una fase de mayor control por parte de las autoridades sanitarias. Para tal efecto se diseñó un instrumento con la finalidad de analizar cómo afecto el confinamiento asociado a la actividad docente en la salud de los profesores en la dimensión personal, familiar y laborar y por ende en su calidad de vida. La investigación realizada es de tipo exploratorio y se aplicó dicha escala a partir de una muestra a conveniencia a 173 profesores de 3 unidades académicas de una Universidad Pública del Estado de Sinaloa.
Published: 2023

24. A blow-up phenomenon for a non-local Liouville-type equation

Author: Battaglia, Luca, Medina, María, Pistoia, Angela, Battaglia, L., Medina, M., and Pistoia, A.
Subjects: Mathematics - Analysis of PDEs, General Mathematics, FOS: Mathematics, Mathematics::Differential Geometry, 35J25 (primary), 35B40, 35B44 (secondary), Analysis, Analysis of PDEs (math.AP)
Abstract: We consider a non-local Liouville equation corresponding to the prescription of the geodesic curvature on the circle. We build a family of solutions which blow up at a critical point of the harmonic extension of the prescribed curvature function, provided some generic assumptions are satisfied., 17 pages, accepted on J. Anal. Math
Published: 2023

25. Hacia una revisión sistemática del concepto de turismo patrimonial

Author: Margherita Libri, Marco Tregua, Miguel Jesús Medina-Viruel, Jesús Claudio Pérez-Gálvez, Libri, Margherita, Tregua, Marco, Jesús Medina-Viruel, Miguel, and Claudio Pérez-Gálvez, Jesús
Subjects: heritage tourism, Geography, Planning and Development, tourism, local culture, General Business, Management and Accounting, cultural tourism
Abstract: La Organización Mundial del Turismo subrayó la importancia del turismo cultural y patrimonial, ya que conlleva y aglutina cultura, arte, creatividad y aprendizaje; además, esta forma de turismo favorece un desarrollo de comunidades que tenga en cuenta el valor de la cultura local. Esta investigación tiene como objetivo la identificación de los temas más importante y recurrentes en la literatura actual sobre esta forma de turismo. Este trabajo de índole teórico puede servir como base y sustento de futuras investigaciones empíricas, ya que ofrece una sistematización de la literatura para que resalten los asuntos relevantes y que describen el comportamiento de los turistas en ciudades, patrimonio de la cultura, es decir, autenticidad, identidad, destino turístico, motivación y comunidad. Se concluye sobre el impacto de un estudio bibliométrico en la base de datos Web of Science y a través de un co-word análisis con Bibliometrix que posibilito una mirada más profunda sobre turismo cultural y patrimonial y destacando los enlaces entre autenticidad, destino y motivaciones, identidad y comunidad; temas brindan la oportunidad para configurar nuevas estrategias en la oferta de experiencias turísticas.
Published: 2023

26. Search for photons above 1019 eV with the surface detector of the Pierre Auger Observatory

Author: Abreu, P., Aglietta, M., Allekotte, I., Almeida Cheminant, K., Almela, A., Alvarez-Muñiz, J., Ammerman Yebra, J., Anastasi, G. A., Anchordoqui, L., Andrada, B., Andringa, S., Aramo, C., Araújo Ferreira, P. R., Arnone, E., Arteaga Velázquez, J. C., Asorey, H., Assis, P., Avila, G., Avocone, E., Badescu, A. M., Bakalova, A., Balaceanu, A., Barbato, F., Bellido, J. A., Berat, C., Bertaina, M. E., Bhatta, G., Biermann, P. L., Binet, V., Bismark, K., Bister, T., Biteau, J., Blazek, J., Bleve, C., Blümer, J., Boháčová, M., Boncioli, D., Bonifazi, C., Bonneau Arbeletche, L., Borodai, N., Brack, J., Bretz, T., Brichetto Orchera, P. G., Briechle, F. L., Buchholz, P., Bueno, A., Buitink, S., Buscemi, M., Büsken, M., Bwembya, A., Caballero-Mora, K. S., Caccianiga, L., Caracas, I., Caruso, R., Castellina, A., Catalani, F., Cataldi, G., Cazon, L., Cerda, M., Chinellato, J. A., Chudoba, J., Chytka, L., Clay, R. W., Cobos Cerutti, A. C., Colalillo, R., Coleman, A., Coluccia, M. R., Conceição, R., Condorelli, A., Consolati, G., Contreras, F., Convenga, F., Correia Dos Santos, D., Covault, C. E., Cristinziani, M., Dasso, S., Daumiller, K., Dawson, B. R., De Almeida, R. M., De Jesús, J., De Jong, S. J., De Mello Neto, J. R. T., De Mitri, I., De Oliveira, J., De Oliveira Franco, D., De Palma, F., De Souza, V., De Vito, E., Del Popolo, A., Deligny, O., Deval, L., Di Matteo, A., Dobre, M., Dobrigkeit, C., D'Olivo, J. C., Domingues Mendes, L. M., Dos Anjos, R. C., Ebr, J., Eman, M., Engel, R., Epicoco, I., Erdmann, M., Escobar, C. O., Etchegoyen, A., Falcke, H., Farmer, J., Farrar, G., Fauth, A. C., Fazzini, N., Feldbusch, F., Fenu, F., Fick, B., Figueira, J. M., Filipčič, A., Fitoussi, T., Fodran, T., Fujii, T., Fuster, A., Galea, C., Galelli, C., García, B., Gemmeke, H., Gesualdi, F., Gherghel-Lascu, A., Ghia, P. L., Giaccari, U., Giammarchi, M., Glombitza, J., Gobbi, F., Gollan, F., Golup, G., Gómez Berisso, M., Gómez Vitale, P. F., Gongora, J. P., González, J. M., González, N., Goos, I., Góra, D., Gorgi, A., Gottowik, M., Grubb, T. D., Guarino, F., Guedes, G. P., Guido, E., Hahn, S., Hamal, P., Hampel, M. R., Hansen, P., Harari, D., Harvey, V. M., Haungs, A., Hebbeker, T., Heck, D., Hojvat, C., Hörandel, J. R., Horvath, P., Hrabovský, M., Huege, T., Insolia, A., Isar, P. G., Janecek, P., Johnsen, J. A., Jurysek, J., Kääpä, A., Kampert, K. H., Keilhauer, B., Khakurdikar, A., Kizakke Covilakam, V. V., Klages, H. O., Kleifges, M., Kleinfeller, J., Knapp, F., Krohm, N., Kunka, N., Lago, B. L., Langner, N., Leigui De Oliveira, M. A., Lenok, V., Letessier-Selvon, A., Lhenry-Yvon, I., Lo Presti, D., Lopes, L., López, R., Lu, L., Luce, Q., Lundquist, J. P., Machado Payeras, A., Mancarella, G., Mandat, D., Manning, B. C., Manshanden, J., Mantsch, P., Marafico, S., Mariani, F. M., Mariazzi, A. G., Mariş, I. C., Marsella, G., Martello, D., Martinelli, S., Martínez Bravo, O., Martins, M. A., Mastrodicasa, M., Mathes, H. J., Matthews, J., Matthiae, G., Mayotte, E., Mayotte, S., Mazur, P. O., Medina-Tanco, G., Melo, D., Menshikov, A., Michal, S., Micheletti, M. I., Miramonti, L., Mollerach, S., Montanet, F., Morejon, L., Morello, C., Müller, A. L., Mulrey, K., Mussa, R., Muzio, M., Namasaka, W. M., Nasr-Esfahani, A., Nellen, L., Nicora, G., Niculescu-Oglinzanu, M., Niechciol, M., Nitz, D., Norwood, I., Nosek, D., Novotny, V., Nožka, L., Nucita, A., Núñez, L. A., Oliveira, C., Palatka, M., Pallotta, J., Papenbreer, P., Parente, G., Parra, A., Pawlowsky, J., Pech, M., Pȩkala, J., Pelayo, R., Pereira Martins, E. E., Perez Armand, J., Pérez Bertolli, C., Perrone, L., Petrera, S., Petrucci, C., Pierog, T., Pimenta, M., Platino, M., Pont, B., Pothast, M., Pourmohammad Shavar, M., Privitera, P., Prouza, M., Puyleart, A., Querchfeld, S., Rautenberg, J., Ravignani, D., Reininghaus, M., Ridky, J., Riehn, F., Risse, M., Rizi, V., Rodrigues De Carvalho, W., Rodriguez Rojo, J., Roncoroni, M. J., Rossoni, S., Roth, M., Roulet, E., Rovero, A. C., Ruehl, P., Saftoiu, A., Saharan, M., Salamida, F., Salazar, H., Salina, G., Sanabria Gomez, J. D., Sánchez, F., Santos, E. M., Santos, E., Sarazin, F., Sarmento, R., Sato, R., Savina, P., Schäfer, C. M., Scherini, V., Schieler, H., Schimassek, M., Schimp, M., Schlüter, F., Schmidt, D., Scholten, O., Schoorlemmer, H., Schovánek, P., Schröder, F. G., Schulte, J., Schulz, T., Sciutto, S. J., Scornavacche, M., Segreto, A., Sehgal, S., Shivashankara, S. U., Sigl, G., Silli, G., Sima, O., Smau, R., Šmída, R., Sommers, P., Soriano, J. F., Squartini, R., Stadelmaier, M., Stanca, D., Stanič, S., Stasielak, J., Stassi, P., Straub, M., Streich, A., Suárez-Durán, M., Sudholz, T., Suomijärvi, T., Supanitsky, A. D., Szadkowski, Z., Tapia, A., Taricco, C., Timmermans, C., Tkachenko, O., Tobiska, P., Todero Peixoto, C. J., Tomé, B., Torrès, Z., Travaini, A., Travnicek, P., Trimarelli, C., Tueros, M., Ulrich, R., Unger, M., Vaclavek, L., Vacula, M., Valdés Galicia, J. F., Valore, L., Varela, E., Vásquez-Ramírez, A., Veberič, D., Ventura, C., Vergara Quispe, I. D., Verzi, V., Vicha, J., Vink, J., Vorobiov, S., Watanabe, C., Watson, A. A., Weindl, A., Wiencke, L., Wilczyński, H., Wittkowski, D., Wundheiler, B., Yushkov, A., Zapparrata, O., Zas, E., Zavrtanik, D., Zavrtanik, M., Zehrer, L., Abreu, P., Aglietta, M., Allekotte, I., Almeida Cheminant, K., Almela, A., Alvarez-Muniz, J., Ammerman Yebra, J., Anastasi, G. A., Anchordoqui, L., Andrada, B., Andringa, S., Aramo, C., Araujo Ferreira, P. R., Arnone, E., Arteaga Velazquez, J. C., Asorey, H., Assis, P., Avila, G., Avocone, E., Badescu, A. M., Bakalova, A., Balaceanu, A., Barbato, F., Bellido, J. A., Berat, C., Bertaina, M. E., Bhatta, G., Biermann, P. L., Binet, V., Bismark, K., Bister, T., Biteau, J., Blazek, J., Bleve, C., Blumer, J., Bohacova, M., Boncioli, D., Bonifazi, C., Bonneau Arbeletche, L., Borodai, N., Brack, J., Bretz, T., Brichetto Orchera, P. G., Briechle, F. L., Buchholz, P., Bueno, A., Buitink, S., Buscemi, M., Busken, M., Bwembya, A., Caballero-Mora, K. S., Caccianiga, L., Caracas, I., Caruso, R., Castellina, A., Catalani, F., Cataldi, G., Cazon, L., Cerda, M., Chinellato, J. A., Chudoba, J., Chytka, L., Clay, R. W., Cobos Cerutti, A. C., Colalillo, R., Coleman, A., Coluccia, M. R., Conceicao, R., Condorelli, A., Consolati, G., Contreras, F., Convenga, F., Correia Dos Santos, D., Covault, C. E., Cristinziani, M., Dasso, S., Daumiller, K., Dawson, B. R., De Almeida, R. M., De Jesus, J., De Jong, S. J., De Mello Neto, J. R. T., De Mitri, I., De Oliveira, J., De Oliveira Franco, D., De Palma, F., De Souza, V., De Vito, E., Del Popolo, A., Deligny, O., Deval, L., Di Matteo, A., Dobre, M., Dobrigkeit, C., D'Olivo, J. C., Domingues Mendes, L. M., Dos Anjos, R. C., Ebr, J., Eman, M., Engel, R., Epicoco, I., Erdmann, M., Escobar, C. O., Etchegoyen, A., Falcke, H., Farmer, J., Farrar, G., Fauth, A. C., Fazzini, N., Feldbusch, F., Fenu, F., Fick, B., Figueira, J. M., Filipcic, A., Fitoussi, T., Fodran, T., Fujii, T., Fuster, A., Galea, C., Galelli, C., Garcia, B., Gemmeke, H., Gesualdi, F., Gherghel-Lascu, A., Ghia, P. L., Giaccari, U., Giammarchi, M., Glombitza, J., Gobbi, F., Gollan, F., Golup, G., Gomez Berisso, M., Gomez Vitale, P. F., Gongora, J. P., Gonzalez, J. M., Gonzalez, N., Goos, I., Gora, D., Gorgi, A., Gottowik, M., Grubb, T. D., Guarino, F., Guedes, G. P., Guido, E., Hahn, S., Hamal, P., Hampel, M. R., Hansen, P., Harari, D., Harvey, V. M., Haungs, A., Hebbeker, T., Heck, D., Hojvat, C., Horandel, J. R., Horvath, P., Hrabovsky, M., Huege, T., Insolia, A., Isar, P. G., Janecek, P., Johnsen, J. A., Jurysek, J., Kaapa, A., Kampert, K. H., Keilhauer, B., Khakurdikar, A., Kizakke Covilakam, V. V., Klages, H. O., Kleifges, M., Kleinfeller, J., Knapp, F., Krohm, N., Kunka, N., Lago, B. L., Langner, N., Leigui De Oliveira, M. A., Lenok, V., Letessier-Selvon, A., Lhenry-Yvon, I., Lo Presti, D., Lopes, L., Lopez, R., Lu, L., Luce, Q., Lundquist, J. P., Machado Payeras, A., Mancarella, G., Mandat, D., Manning, B. C., Manshanden, J., Mantsch, P., Marafico, S., Mariani, F. M., Mariazzi, A. G., Maris, I. C., Marsella, G., Martello, D., Martinelli, S., Martinez Bravo, O., Martins, M. A., Mastrodicasa, M., Mathes, H. J., Matthews, J., Matthiae, G., Mayotte, E., Mayotte, S., Mazur, P. O., Medina-Tanco, G., Melo, D., Menshikov, A., Michal, S., Micheletti, M. I., Miramonti, L., Mollerach, S., Montanet, F., Morejon, L., Morello, C., Muller, A. L., Mulrey, K., Mussa, R., Muzio, M., Namasaka, W. M., Nasr-Esfahani, A., Nellen, L., Nicora, G., Niculescu-Oglinzanu, M., Niechciol, M., Nitz, D., Norwood, I., Nosek, D., Novotny, V., Noa3/4ka, L., Nucita, A., Nunez, L. A., Oliveira, C., Palatka, M., Pallotta, J., Papenbreer, P., Parente, G., Parra, A., Pawlowsky, J., Pech, M., Pekala, J., Pelayo, R., Pereira Martins, E. E., Perez Armand, J., Perez Bertolli, C., Perrone, L., Petrera, S., Petrucci, C., Pierog, T., Pimenta, M., Platino, M., Pont, B., Pothast, M., Pourmohammad Shavar, M., Privitera, P., Prouza, M., Puyleart, A., Querchfeld, S., Rautenberg, J., Ravignani, D., Reininghaus, M., Ridky, J., Riehn, F., Risse, M., Rizi, V., Rodrigues De Carvalho, W., Rodriguez Rojo, J., Roncoroni, M. J., Rossoni, S., Roth, M., Roulet, E., Rovero, A. C., Ruehl, P., Saftoiu, A., Saharan, M., Salamida, F., Salazar, H., Salina, G., Sanabria Gomez, J. D., Sanchez, F., Santos, E. M., Santos, E., Sarazin, F., Sarmento, R., Sato, R., Savina, P., Schafer, C. M., Scherini, V., Schieler, H., Schimassek, M., Schimp, M., Schluter, F., Schmidt, D., Scholten, O., Schoorlemmer, H., Schovanek, P., Schroder, F. G., Schulte, J., Schulz, T., Sciutto, S. J., Scornavacche, M., Segreto, A., Sehgal, S., Shivashankara, S. U., Sigl, G., Silli, G., Sima, O., Smau, R., Smida, R., Sommers, P., Soriano, J. F., Squartini, R., Stadelmaier, M., Stanca, D., Stanic, S., Stasielak, J., Stassi, P., Straub, M., Streich, A., Suarez-Duran, M., Sudholz, T., Suomijarvi, T., Supanitsky, A. D., Szadkowski, Z., Tapia, A., Taricco, C., Timmermans, C., Tkachenko, O., Tobiska, P., Todero Peixoto, C. J., Tome, B., Torres, Z., Travaini, A., Travnicek, P., Trimarelli, C., Tueros, M., Ulrich, R., Unger, M., Vaclavek, L., Vacula, M., Valdes Galicia, J. F., Valore, L., Varela, E., Vasquez-Ramirez, A., Veberic, D., Ventura, C., Vergara Quispe, I. D., Verzi, V., Vicha, J., Vink, J., Vorobiov, S., Watanabe, C., Watson, A. A., Weindl, A., Wiencke, L., Wilczynski, H., Wittkowski, D., Wundheiler, B., Yushkov, A., Zapparrata, O., Zas, E., Zavrtanik, D., Zavrtanik, M., and Zehrer, L.
Subjects: Astronomy, Experimental High Energy Physics, Astronomy and Astrophysics, High Energy Physics, ddc:620, cosmic ray experiments, gamma ray detectors, ultra high energy cosmic rays, ultra high energy photons and neutrinos, Engineering & allied operations
Abstract: We use the surface detector of the Pierre Auger Observatory to search for air showers initiated by photons with an energy above 1019 eV. Photons in the zenith angle range from 30∘ to 60∘ can be identified in the overwhelming background of showers initiated by charged cosmic rays through the broader time structure of the signals induced in the water-Cherenkov detectors of the array and the steeper lateral distribution of shower particles reaching ground. Applying the search method to data collected between January 2004 and June 2020, upper limits at 95% CL are set to an E-2 diffuse flux of ultra-high energy photons above 1019 eV, 2 × 1019 eV and 4 × 1019 eV amounting to 2.11 × 10-3, 3.12 × 10-4 and 1.72 × 10-4 km-2 sr-1 yr-1, respectively. While the sensitivity of the present search around 2 × 1019 eV approaches expectations of cosmogenic photon fluxes in the case of a pure-proton composition, it is one order of magnitude above those from more realistic mixed-composition models. The inferred limits have also implications for the search of super-heavy dark matter that are discussed and illustrated.
Published: 2023

27. Chiles en México

Author: Aguilar Meléndez, Araceli, Andalón González, Mónica Guadalupe, Bañuelos Flores, Noemí, Barros, Cristina, Cagnato, Clarissa, Cayetano Antonio, Medardo, Corona Torres, Tarsicio, Cortes Santiago, Gloria Ester, Cruz Gracia, Wilfrido Martín, Demanget, Magali, Domínguez Yescas, Reyna, Hernández Martínez, Magdalena, Hernández Osorio, Crescencio, Katz, Esther, Linares Sosa, Gabriela, López Binnqüist, Citlalli, López Tirzo, José, Manzanero Medina, Aída, Manzanero Medina, Gladys Isabel, Manzanero Medina, Verónica, Martínez Ramírez, Adela, Martínez Torres, Héctor Leonardo, Montes Hernández, Salvador, Montúfar López, Aurora, Paraíso, Raquel, Pérez Apango, Yuyultzin, Ramírez Meraz, Moisés, Ramos Abascal, María Isabel, Robles Parra, Jesús Martín, Rómulo Mendoza, Rubén Hernández, Ruiz Bello, Romeo, Ruiz López, Analy, Sánchez Cortés, Clemencia Elizabeth, Sandoval Bautista, Osvaldo, Santiago, Perla, Vásquez Dávila, Marco Antonio, Vibrans, Heike, Vásquez Dávila, Marco Antonio, Aguilar Meléndez, Araceli, Katz, Esther, and Manzanero Medina, Gladys Isabel
Subjects: gastronomie, usages médicaux, usos culturales, JHM, anthropologie de l'alimentation, semilla, identidad cultural, chile, historia de la alimentación, antropología de la alimentación, Cultural studies, piment, estudios culturales, identité culturelle, gastronomía, études culturelles, SOC002000, ethnobotanique, usages culturels, usos médicos, graine, histoire de l'alimentation, etnobotánica
Abstract: Un grupo de investigadores de la Universidad Veracruzana, del Instituto Tecnológico del Valle de Oaxaca, del CIIDIR Oaxaca del Instituto Politécnico Nacional y del Instituto de Investigación para el Desarrollo, de Francia, se ha dado a la tarea de conjuntar los estudios culturales que sobre el chile se han desarrollado en México. En un esfuerzo interdisciplinario, reúnen textos que abordan la temática de este fruto desde muy diversas perspectivas: antropológica, gastronómica, histórica, biológica, medicinal… Su labor ha rendido más de un resultado: la primera compilación (Los chiles que le dan sabor al mundo) fue publicada en 2018. En alcance de esta, el segundo volumen amplía y profundiza los saberes alrededor de los chiles, del mito a la genética, desde la dispersión de las semillas hasta los usos culinarios en recetas milenarias, en la cocina familiar o en restaurantes, y los usos alimenticios, curativos y rituales en espacios rurales así como urbanos. Queda así en evidencia la importancia del picante como marcador de identidad local latinoamericana: “dime qué chi-le consumes y te diré de dónde eres”. Y es que, como todos lo sabemos, en los hogares mexicanos no puede faltar una salsa, ya sea de serrano, piquín, habanero o de jalapeño. De esta manera, en Chiles en México. Historias, culturas y ambientes se da continuidad y se enriquece nuestro aprecio por los sabores de México, por su riqueza gastronómica y la herencia cultural de generaciones. Que este rescate siembre en el lector la necesidad de valorar y de preservar lo que este sabroso ingrediente representa.
Published: 2023

28. Kerion of Celso: Clinical Features, Diagnosis and Therapeutic Approaches

Author: Miguel A. Ramírez-Madrigal, Patricia Flores Troche, Juan Francisco Medina Ledesma, Esmeralda Hernández Lerma, and Mario Eduardo Elias Medina
Subjects: Diagnosis, EPIDEMIOLOGY,Mesenteric
Abstract: Querion de Celso, also known as Celso abscess, is a rare and severe inflammatory condition that arises as a complication of folliculitis. It is characterized by the formation of a purulent and fluctuant abscess in the pilosebaceous region. This dermatological disorder is primarily associated with the invasion of pathogenic bacteria, most commonly Staphylococcus aureus, into the hair follicles and sebaceous glands. Clinically, kerion de Celso presents as a prominent, erythematous, warm, and fluctuant lesion, often accompanied by local pain, restricted movement, and potential systemic symptoms such as fever and malaise. The diagnosis of kerion de Celso relies on a comprehensive evaluation, including clinical assessment, histopathological findings, and microbiological analysis. These diagnostic modalities support the presence of an intense inflammatory response and aid in identifying the causative agent. Treatment of kerion de Celso necessitates a multidisciplinary approach. Systemic antibiotics are essential to eliminate the underlying bacterial infection, while analgesics and anti-inflammatory agents provide symptomatic relief. Surgical incision and drainage may be required in cases of extensive abscess formation. In more complex situations, immunosuppressive therapy may be considered to modulate the exaggerated inflammatory response. Adequate wound care and close follow-up are crucial to ensure successful resolution and prevent long-term complications. In summary, Celso's kerion is a rare but potentially severe condition that requires prompt recognition and appropriate management to minimize complications and promote healing. Understanding the clinical, etiological, and therapeutic aspects of this condition is essential for healthcare professionals to deliver optimal care and improve clinical outcomes.
Published: 2023
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29. Uterine cervical stenosis: from classification to advances in management. Overcoming the obstacles to access the uterine cavity

Author: Vitale, Salvatore Giovanni, De Angelis, Maria Chiara, Della Corte, Luigi, Saponara, Stefania, Carugno, Jose, Laganà, Antonio Simone, Török, Péter, Tinelli, Raffaele, Pérez-Medina, Tirso, Ertas, Sinem, Urman, Bulent, Angioni, Stefano, Vitale, Salvatore Giovanni, De Angelis, Maria Chiara, Della Corte, Luigi, Saponara, Stefania, Carugno, Jose, Laganà, Antonio Simone, Török, Péter, Tinelli, Raffaele, Pérez-Medina, Tirso, Ertas, Sinem, Urman, Bulent, and Angioni, Stefano
Subjects: Infertility, Therapy, Hysteroscopy, Cervical stenosi, Settore MED/40 - Ginecologia E Ostetricia
Abstract: Background: To date hysteroscopy is the gold standard technique for the evaluation and management of intrauterine pathologies. The cervical canal represents the access route to the uterine cavity. The presence of cervical stenosis often makes entry into the uterine cavity difficult and occasionally impossible. Cervical stenosis has a multifactorial etiology. It is the result of adhesion processes that can lead to the narrowing or total obliteration of the cervical canal. Purpose: In this review, we summarize the scientific evidence about cervical stenosis, aiming to identify the best strategy to overcome this challenging condition. Methods: The literature review followed the scale for the quality assessment of narrative review articles (SANRA). All articles describing the hysteroscopic management of cervical stenosis were considered eligible. Only original papers that reported data on the topic were included. Results: Various strategies have been proposed to address cervical stenosis, including surgical and non-surgical methods. Medical treatments such as the preprocedural use of cervical-ripening agents or osmotic dilators have been explored. Surgical options include the use of cervical dilators and hysteroscopic treatments. Conclusions: Cervical stenosis can present challenges in achieving successful intrauterine procedures. Operative hysteroscopy has been shown to have the highest success rate, particularly in cases of severe cervical stenosis, and is currently considered the gold standard for managing this condition. Despite the availability of miniaturized instruments that have made the management of cervical stenosis more feasible, it remains a complex task, even for experienced hysteroscopists.
Published: 2023

30. Quality of public space and sustainable development goals: analysis of nine urban projects in Spanish cities

Author: Raimundo Bambó Naya, Pablo de la Cal Nicolás, Carmen Díez Medina, Isabel Ezquerra, Sergio García-Pérez, and Javier Monclús
Subjects: Urban Studies, Archeology, Architecture, Building and Construction
Abstract: The starting point of this research is the urban model promoted by the United Nations through the Sustainable Development Goals (SDGs). The importance of public spaces is especially highlighted in Goal 11.7: “provide universal access to safe, inclusive, and accessible, green, and public spaces …” The quality of public spaces can be properly assessed by reconsidering the quality indicators and investigating their development potential, which is the main focus of our research. This study is based on a theoretical and methodological reflection on the quality of public space, considering the contributions of some contemporary urban traditions and a few recent experiences. From this perspective, a variety of public space projects developed in the European sphere have been selected and analyzed. The quality parameters identified in this initial analysis were then applied to the analysis of nine representative case studies in three Spanish cities (Madrid, Barcelona, and Zaragoza). The main goal is to propose a methodology that helps to evaluate the quality of those public spaces and determine its relationship with the safety, accessibility, and inclusiveness conditions they offer.
Published: 2023

31. In vivo tracing of immunostimulatory raw starch microparticles after mucosal administration

Author: Nathaly Vasquez-Martínez, Daniel Guillén, Silvia Andrea Moreno-Mendieta, Pedro Medina-Granados, Rocío Guadalupe Casañas-Pimentel, Eduardo San Martín-Martínez, Miguel Ángel Morales, Sergio Sanchez, and Romina Rodríguez-Sanoja
Subjects: Pharmaceutical Science, General Medicine, Biotechnology
Published: 2023

32. Diagnóstico incidental del cáncer de vejiga en España. Estudio observacional a nivel nacional

Author: J.M. Gaya, A. Territo, S. Woldu, I. Schwartzmann, P. Verri, L. González-Pérez, J.M. Cózar, B. Miñana, R.A. Medina, F. de la Rosa-Kehrmann, F. Lozano-Palacio, M.J. Ribal, C. Hernández, J.J. Castiñeiras, M.J. Requena, J. Moreno, J.A. Caraballido, V. Baena, A. Breda, and J. Palou Redorta
Subjects: Urology
Published: 2023

33. Solutions of matrix equations with weak fuzzy equivalence relations

Author: Jesús Medina, Vanja Stepanović, and Andreja Tepavčević
Subjects: Information Systems and Management, Artificial Intelligence, Control and Systems Engineering, Weak fuzzy equivalence relation, Matrix equations, Linear equation, Software, Lattice valued, Computer Science Applications, Theoretical Computer Science
Abstract: In this paper, we are solving matrix equations where the operation on matrices might not be a standard composition, but it can be any convenient binary operation. We use fuzzy (lattice valued) techniques in which a particular fuzzy weak equivalence relation and its compatibility with the matrix operation plays the central role. This fuzzy weak equivalence relation is weakly reflexive, symmetric, transitive, and compatible with the matrix operation. We obtain approximate solutions of two main types of matrix equations. We also tackle the question of the uniqueness of solutions (which are unique up to the fuzzy weak equivalence relation). © 2023 Elsevier Inc.
Published: 2023

34. Design and implementation of a digital health home spirometry intervention for remote monitoring of lung transplant function

Author: Anobel Y. Odisho, Andrew W. Liu, Ali R. Maiorano, M. Olivia A. Bigazzi, Eli Medina, Lorriana E. Leard, Rupal Shah, Aida Venado, Alyssa Perez, Jeffrey Golden, Mary Ellen Kleinhenz, Nicholas A. Kolaitis, Julia Maheshwari, Binh N. Trinh, Jasleen Kukreja, John Greenland, Daniel Calabrese, Aaron B. Neinstein, Jonathan P. Singer, and Steven R. Hays
Subjects: Pulmonary and Respiratory Medicine, Transplantation, Surgery, Cardiology and Cardiovascular Medicine
Published: 2023

35. Joint models for longitudinal and discrete survival data in credit scoring

Author: Victor Medina-Olivares, Raffaella Calabrese, Jonathan Crook, and Finn Lindgren
Subjects: Bayesian joint models, Information Systems and Management, General Computer Science, Modeling and Simulation, discrete time, autoregressive process, Management Science and Operations Research, Industrial and Manufacturing Engineering, OR in banking
Abstract: The inclusion of time-varying covariates into survival analysis has led to better predictions of the time to default in behavioural credit scoring models. However, when these time-varying covariates are endogenous, there are two major problems: estimation bias of the survival model and lack of a prediction framework for future values of both the event and the endogenous time-varying covariates. Joint models for longitudinal and survival data is an appropriate framework to model the mutual evolution of the survival time and the endogenous time-varying covariates. To the best of our knowledge,this paper explores for the first time the application of discrete-time joint models to credit scoring. Moreover, we propose a novel extension to the joint model literature by including autoregressive terms in modelling the endogenous time-varying covariates. We present the method via simulations and by applying it to US mortgage loans. The empirical analysis shows, first, that discrete joint models can increase the discrimination performance compared to survival models. Second, when an autoregressive term is included, this performance can be further improved.
Published: 2023

36. Glide Symmetry Applied to the Design of Common-Mode Rejection Filters Based on Complementary Split-Ring Resonators

Author: Armando Fernández-Prieto, Victoria dos Santos, Jesús Martel, Jose L. Medrán del Río, Francisco Mesa, Oscar Quevedo-Teruel, Rafael R. Boix, and Francisco Medina
Subjects: Electrical and Electronic Engineering
Published: 2023

37. The anterior and pulvinar thalamic nuclei interactions in mesial temporal lobe seizure networks

Author: Hugo Soulier, Francesca Pizzo, Aude Jegou, Stanislas Lagarde, Elodie Garnier, Julia Makhalova, Samuel Medina Villalon, Romain Carron, Christian Bénar, and Fabrice Bartolomei
Subjects: Neurology, Physiology (medical), Neurology (clinical), Sensory Systems
Published: 2023

38. Endocrine disruptors in plastics alter β-cell physiology and increase the risk of diabetes mellitus

Author: Juan Martínez-Pinna, Roberto Sempere-Navarro, Regla M. Medina-Gali, Esther Fuentes, Ivan Quesada, Robert M. Sargis, Leonardo Trasande, Angel Nadal, Universidad de Alicante. Departamento de Fisiología, Genética y Microbiología, and Fisiología Neuroendocrina (FINE)
Subjects: Physiology, Insulin secretion, Physiology (medical), Endocrinology, Diabetes and Metabolism, Diabetes, β-cells, Insulin resistance, Endocrine disruptors
Abstract: Plastic pollution breaks a planetary boundary threatening wildlife and humans through its physical and chemical effects. Of the latter, the release of endocrine disrupting chemicals (EDCs) has consequences on the prevalence of human diseases related to the endocrine system. Bisphenols (BPs) and phthalates are two groups of EDCs commonly found in plastics that migrate into the environment and make low-dose human exposure ubiquitous. Here we review epidemiological, animal, and cellular studies linking exposure to BPs and phthalates to altered glucose regulation, with emphasis on the role of pancreatic β-cells. Epidemiological studies indicate that exposure to BPs and phthalates is associated with diabetes mellitus. Studies in animal models indicate that treatment with doses within the range of human exposure decreases insulin sensitivity and glucose tolerance, induces dyslipidemia, and modifies functional β-cell mass and serum levels of insulin, leptin, and adiponectin. These studies reveal that disruption of β-cell physiology by EDCs plays a key role in impairing glucose homeostasis by altering the mechanisms used by β-cells to adapt to metabolic stress such as chronic nutrient excess. Studies at the cellular level demonstrate that BPs and phthalates modify the same biochemical pathways involved in adaptation to chronic excess fuel. These include changes in insulin biosynthesis and secretion, electrical activity, expression of key genes, and mitochondrial function. The data summarized here indicate that BPs and phthalates are important risk factors for diabetes mellitus and support a global effort to decrease plastic pollution and human exposure to EDCs. The author’s laboratories are supported by Ministerio de Ciencia e Innovación, Agencia Estatal de Investigación (AEI) and Fondo Europeo de Desarrollo Regional (FEDER) grant PID2020-117294RB-I00 (AN and JM-P), Generalitat Valenciana PROMETEO II/2020/006 (AN), and European Union’s Horizon 2020 research and innovation programme under grant agreement GOLIATH No. 825489 (AN). This work was supported by the National Institutes of Health (R01 ES028879 and P30 ES027792 supporting RMS).
Published: 2023

39. Whole genome analysis of Gram-negative bacteria using the EPISEQ CS application and other bioinformatic platforms

Author: Ulises Garza-Ramos, Nadia Rodríguez-Medina, Carlos Córdova-Fletes, Daira Rubio-Mendoza, Christopher J. Alonso-Hernández, Luis Esaú López-Jácome, Rao Morfín-Otero, Eduardo Rodríguez-Noriega, Fabián Rojas-Larios, María del Rosario Vázquez-Larios, Alfredo Ponce-de-Leon, Elena Victoria Choy-Chang, Rafael Franco-Cendejas, Bernardo Alfonso Martinez-Guerra, Cecilia Teresita Morales-de-La-Peña, Juan Pablo Mena-Ramírez, Eduardo López-Gutiérrez, Ricardo García-Romo, Bertha Ballesteros-Silva, Alejandro Valadez-Quiroz, Laura Karina Avilés-Benítez, José Manuel Feliciano-Guzmán, Talia Pérez-Vicelis, María del Consuelo Velázquez-Acosta, Cecilia Padilla-Ibarra, Laura Isabel López-Moreno, Reyna Edith Corte-Rojas, Carlos Antonio Couoh-May, María Angelina Quevedo-Ramos, Maribel López-García, Gabriela Chio-Ortiz, Mariana Gil-Veloz, Alejandro Molina-Chavarria, Javier Paul Mora-Domínguez, Daniel Romero-Romero, Francisco Javier May-Tec, and Elvira Garza-González
Subjects: Microbiology (medical), Immunology, Immunology and Allergy, Microbiology
Published: 2023

40. Towards recycling of waste carbon fiber: Strength, morphology and structural features of recovered carbon fibers

Author: A. Salas, M.E. Berrio, S. Martel, A. Díaz-Gómez, Daniel A. Palacio, V. Tuninetti, C. Medina, and M.F. Meléndrez
Subjects: Waste Management and Disposal
Published: 2023

41. Gastrointestinal symptoms and complications in patients hospitalized due to COVID-19, an international multicentre prospective cohort study (TIVURON project)

Author: Karina Cárdenas-Jaén, Sergio A. Sánchez-Luna, Alicia Vaillo-Rocamora, Micaela Riat Castro-Zocchi, Laura Guberna-Blanco, Daniel Useros-Brañas, José M. Remes-Troche, Antonio Ramos-De la Medina, Bryan A. Priego-Parra, José A. Velarde-Ruiz Velasco, Pedro Martínez-Ayala, Álvaro Urzúa, Dannette Guiñez-Francois, Katarzyna M. Pawlak, Katarzyna Kozłowska-Petriczko, Irati Gorroño-Zamalloa, Clara Urteaga-Casares, Inmaculada Ortiz-Polo, Adolfo del Val Antoñana, Edgard E. Lozada-Hernández, Enrique Obregón-Moreno, Guillermo García-Rayado, María José Domper-Arnal, Diego Casas-Deza, Elena I. Esteban-Cabello, Luis A. Díaz, Arnoldo Riquelme, Helena Martínez-Lozano, Francisco Navarro-Romero, Ignasi Olivas, Guillem Iborra-Muñoz, Alicia Calero-Amaro, Ibán Caravaca-García, Francisco J. Lacueva-Gómez, Rubén Pastor-Mateu, Berta Lapeña-Muñoz, Violeta Sastre-Lozano, Nazaret M. Pizarro-Vega, Luigi Melcarne, Marc Pedrosa-Aragón, José J. Mira, Aurora Mula MStat, Irene Carrillo, and Enrique de-Madaria
Subjects: Hepatology, gastrointestinal symptoms, complicaciones gastrointestinales, gastrointestinal complications, Gastroenterology, COVID-19, hospitalización, hepatitis, síntomas gastrointestinales, hospitalization
Abstract: Retrospective studies suggest that coronavirus disease (COVID-19) commonly involves gastrointestinal (GI) symptoms and complications. Our aim was to prospectively evaluate GI manifestations in patients hospitalized for COVID-19.This international multicentre prospective cohort study recruited COVID-19 patients hospitalized at 31 centres in Spain, Mexico, Chile, and Poland, between May and September 2020. Patients were followed-up until 15 days post-discharge and completed comprehensive questionnaires assessing GI symptoms and complications. A descriptive analysis as well as a bivariate and multivariate analysis were performer using binary logistic regression. p0.05 was considered significant.Eight hundred twenty-nine patients were enrolled; 129 (15.6%) had severe COVID-19, 113 (13.7%) required ICU admission, and 43 (5.2%) died. Upon admission, the most prevalent GI symptoms were anorexia (n=413; 49.8%), diarrhoea (n=327; 39.4%), nausea/vomiting (n=227; 27.4%), and abdominal pain (n=172; 20.7%), which were mild/moderate throughout the disease and resolved during follow-up. One-third of patients exhibited liver injury. Non-severe COVID-19 was associated with ≥2 GI symptoms upon admission (OR 0.679; 95% CI 0.464-0.995; p=0.046) or diarrhoea during hospitalization (OR 0.531; 95% CI 0.328-0.860; p=0.009). Multivariate analysis revealed that worse hospital outcomes were not independently associated with liver injury or GI symptoms.GI symptoms were more common than previously documented, and were mild, rapidly resolved, and not independently associated with COVID-19 severity. Liver injury was a frequent complication in hospitalized patients not independently associated with COVID-19 severity.
Published: 2023

42. A VCO-ADC Linearized by a Capacitive Frequency-to-Current Converter

Author: Ruben Garvi, Javier Granizo, Eric Gutierrez, Victor Medina, Andreas Wiesbauer, and Luis Hernandez
Subjects: Electrical and Electronic Engineering
Published: 2023

43. Olfactory bulbectomy induces nociceptive alterations associated with gliosis in male rats

Author: Gumaro Galindo-Paredes, Gonzalo Flores, and Julio César Morales-Medina
Subjects: General Neuroscience
Published: 2023

44. Monitoring, Support and Inter-Learning in Teaching Performance in Basic Education of the Area of Mathematics. A Case Study in Puno (Perú)

Author: Judith Annie Bautista-Quispe, Edwin Gustavo Estrada-Araoz, Marisol Yana-Salluca, Zaida Esther Callata Gallegos, Ronald Raul Arce Coaquira, Benjamin Velazco Reyes, Jaffet Sillo Sosa, and Victor Raul Medina Alanoca
Subjects: Education
Abstract: The objective of this article is to determine the influence of monitoring, support and inter-learning on teaching performance in the area of high school Mathematics in Puno (Peru). This investigation was motivated by the results obtained by students in the Student Census Evaluation, as one of the components is the teaching factor in every pedagogical triangle. For this reason, a quantitative cross-sectional study with a descriptive-explanatory design was performed. The data were collected through a survey established by the Ministry of Education and the sample was comprised of 16 teachers of Mathematics. The results showed that monitoring, support, and inter-learning had a significant and positive influence on teaching performance. The present research shows that monitoring, support, and inter-learning have implications for teacher performance and, ultimately, for the quality of education provided to students. This strategy helps to identify teachers’ strengths and weaknesses, improve communication among teachers, and promote collaborative work. Therefore, it is important to implement effective programs of pedagogical monitoring and support in educational institutions to enhance the pedagogical practices of teachers.
Published: 2023

45. Gestión de un observatorio turístico de un pueblo mágico mediante inteligencia de negocios

Author: Nalleli Hernández Marroquin, Gabriela Cabrera Zepeda, Edna Araceli Romero Flores, Fernando Aguirre y Hernández, and Marcos Salazar Medina
Subjects: General Medicine
Abstract: El presente artículo tiene como finalidad explicar el desarrollo de un proyecto cuyo objetivo es gestionar un Observatorio turístico, aplicando Inteligencia de Negocios, con la finalidad de medir los indicadores del comportamiento del turismo en un Pueblo Mágico de México. Como parte de un programa de la Secretaría de Turismo que inició en 2001, se otorga el título de Pueblo Mágico a los municipios que cumplen con ciertas características y requisitos, destacando la riqueza cultural del país por medio de su historia, usos y costumbres, con el propósito de activar el turismo nacional en esas zonas. Los municipios participantes son evaluados año con año a partir de su incorporación, uno de los requisitos es la creación de un Observatorio Turístico que pueda dar información sobre el desarrollo de los pueblos a partir de su nombramiento. Para la creación del Observatorio Turístico se utiliza la metodología propuesta por la Organización Mundial de Turismo, donde se establece desde la delimitación del destino, los procesos participativos de los diferentes interesados hasta la presentación de los resultados. Otra metodología aplicada es la Inteligencia de Negocios que ayuda con la recolección, organización y análisis de la información, para la obtención de los resultados finales.
Published: 2023

46. Dinámica de la cadena de producción del bocadillo veleño: un acercamiento desde el desarrollo local

Author: Iván Darío Medina Rojas, Eliana Patricia Sánchez Parra, and Yedy Alejandra Solís Montaño
Abstract: El bocadillo veleño es un manjar que se disfruta desde varias generaciones; más allá de su valor cultural, fomenta el desarrollo económico y social a nivel local. El presente escrito realiza un aporte mediante una aproximación a la cadena de valor de este producto contemplando sus eslabones constitutivos a modo de taxonomía. Mediante una investigación de tipo descriptivo, se realiza un breve análisis en diez empresas productoras de bocadillo ubicadas en los municipios de Vélez, Barbosa y Moniquirá sobre aspectos de constitución organizacional, competitividad, asociatividad, exportación, tecnología e innovación. Sumado a ello un acercamiento a la dinámica de los otros eslabones presentes en la cadena: cultivadores y transformadores de hoja de bijao, productores de guayaba y organismos que se encargan de agremiar a los agentes presentes. Como principal resultado se observa un análisis de elementos que constituyen valor en la cadena, el rol del territorio en el desarrollo local y el papel de sus agentes productivos. No obstante, a pesar de los esfuerzos del sector, falta un mayor grado de fortalecimiento, por lo que la academia podría fungir como un actor clave de apoyo.
Published: 2023

47. Phase I Study of SYNB1891, an Engineered E. coli Nissle Strain Expressing STING Agonist, with and without Atezolizumab in Advanced Malignancies

Author: Jason J. Luke, Sarina A. Piha-Paul, Theresa Medina, Claire F. Verschraegen, Mary Varterasian, Aoife M. Brennan, Richard J. Riese, Anna Sokolovska, James Strauss, David L. Hava, and Filip Janku
Subjects: Cancer Research, Oncology
Abstract: Purpose: SYNB1891 is a live, modified strain of the probiotic Escherichia coli Nissle 1917 (EcN) engineered to produce cyclic dinucleotides under hypoxia, leading to STimulator of INterferon Genes (STING) activation in phagocytic antigen-presenting cells in tumors and activating complementary innate immune pathways. Patients and Methods: This first-in-human study (NCT04167137) enrolled participants with refractory advanced cancers to receive repeat intratumoral injections of SYNB1891 either alone or in combination with atezolizumab, with the primary objective of evaluating the safety and tolerability of both regimens. Results: Twenty-four participants received monotherapy across six cohorts, and 8 participants received combination therapy in two cohorts. Five cytokine release syndrome events occurred with monotherapy, including one that met the criteria for dose-limiting toxicity at the highest dose; no other SYNB1891-related serious adverse events occurred, and no SYNB1891-related infections were observed. SYNB1891 was not detected in the blood at 6 or 24 hours after the first intratumoral dose or in tumor tissue 7 days following the first dose. Treatment with SYNB1891 resulted in activation of the STING pathway and target engagement as assessed by upregulation of IFN-stimulated genes, chemokines/cytokines, and T-cell response genes in core biopsies obtained predose and 7 days following the third weekly dose. In addition, a dose-related increase in serum cytokines was observed, as well as stable disease in 4 participants refractory to prior PD-1/L1 antibodies. Conclusions: Repeat intratumoral injection of SYNB1891 as monotherapy and in combination with atezolizumab was safe and well tolerated, and evidence of STING pathway target engagement was observed.
Published: 2023

48. Small and medium-sized companies in the COVID-19 era: challenges and prospects

Author: Juan Carlos Rea Anguiano, Rafael Medina Orozco, Víctor Alfonso Salazar Flores, Mónica Rea Anguiano, Abdón Hernández Alvarado, and Cynthia Berenice Castro Aranda
Subjects: Marketing, Economics and Econometrics, General Chemical Engineering, General Materials Science
Abstract: The pandemic has significantly affected small and medium-sized enterprises (SMEs) due to their lack of financial and technological resources. The disruption of supply chains has affected the ability of SMEs to obtain raw materials and finished goods, which has increased production costs and decreased revenue. Additionally, digitization has become a crucial tool for businesses seeking to adapt to the pandemic, but many SMEs have faced significant challenges in terms of a lack of technology skills and resources, and limited connectivity in some regions. Government support has been instrumental in helping SMEs survive during the pandemic. Government programs that provide financial aid and business advice have been especially effective for SMEs. However, it is important that government support programs are accessible and easy to understand for SMEs, and that they are tailored to the specific needs of each sector.
Published: 2023

49. Incidencia de la sostenibilidad en la gestión educativa, la situación latinoamericana

Author: Iván Leonardo Medina Alvarado
Abstract: Ser sostenible se ha convertido en una de las metas más destacadas no solo por los empresarios y los gobiernos, sino que se ha evidenciado que ha cobrado un rol determinante al interior de los sistemas educativos, llevando la premisa de prologar con el paso del tiempo propuestas educativas que atiendan a las necesidades de los diferentes grupos poblacionales; ahora bien, esta prolongación en el tiempo requiere que se cuente con la pertinencia necesaria para atender oportunamente las necesidades y particularidades de la sociedad, ya que no se buscan imponer modelos educativos o propuestas educacionales, todo lo contrario, se orientan a una constante articulación entre las necesidades y las propuestas para atender dichas necesidades, donde es claro comprender que la participación social es la clave del éxito. Así las cosas, se abordan tres ejes centrales que permiten comprender como incide la sostenibilidad la gestión educativa, y como quienes hacen de la educación un proceso de dignificación del ser humano, deben comprender que no solo es en una dirección tal proceso educativo, sino que es un proceso bidireccional y multidireccional, de allí que se abordan los siguientes tres ejes: a) La sostenibilidad en el gobierno educativo, b) Relacionamiento con los stakeholders, y c) Valor compartido en la educación; pareciese que esta concepción de la sostenibilidad es distante de la realidad educativa, salvo que en el siguiente documento se analiza tal integración a partir de la mirada latinoamericana.
Published: 2023

50. Implementación del Geoportal para la Junta Administradora de Agua Potable y Saneamiento – JAAPyS - Santa Fé Centro, año 2023

Author: Maricela Araceli Espín Morejón, Mónica Elizabeth Bonilla Manobanda, Segundo Rafael Medina Velasco, and Henry Fernando Vallejo Ballesteros
Abstract: Introducción: en nuestro país se ha creado la respectiva legislación y los organismos de control que regula el trabajo de las Juntas Administradoras de Agua encargadas de la gestión del recurso hídrico, las mismas que deben gestionar elementos de infraestructura del sistema de agua potable (captaciones, redes de conducción, redes de distribución, válvulas de control, acometidas domiciliarias), información económica de cobros por consumo de agua, registro de usuarios (nuevos y cambio de beneficiarios), datos de fallos, reparaciones, ampliaciones de la infraestructura; sin embargo, debido a los limitados recursos económicos que manejan estas organizaciones es difícil que puedan prestar servicios de calidad, aprovechar de manera eficiente el recurso hídrico, garantizar la conservación de fuentes hídricas y la dotación del servicio de agua potable a todos los habitantes de la comunidad. Objetivos: apoyar al cumplimiento del sexto objetivo de la Agenda 2030 sobre el Desarrollo Sostenible aprobada por la ONU en 2015 Agua Limpia y Saneamiento, ha sido una preocupación de varias organizaciones a nivel mundial, entre ellas la FAO, UNESCO WWAP, PNUD, UNECE y UNEP, quienes se han propuesto ayudar a que se realice una eficiente gestión del recurso hídrico en beneficio de los usuarios; con este fin se utilizan las tecnologías digitales. Metodología: esta investigación es de tipo aplicada, con enfoque mixto, de campo y documental y descriptiva, para lo cual se estableció una metodología de recolección de datos técnicos sobre el comportamiento del recurso hídrico y las redes de distribución del sistema de agua potable. Resultados: metodología para levantar información para un sistema de agua potable, mapas de la infraestructura existente, listados actualizados de los usuarios y el geoportal utilizando software libre con información obtenida de la JAAP-S Santa Fé Centro. Conclusiones: la JAAP-S cuenta con un geoportal, en el cual los directivos fundamentalmente podrán visualizar los cambios que ocurran en los elementos de la infraestructura física del sistema de agua potable a través del tiempo. Área de estudio general: Software. Área de estudio específica: Sistemas de información geográfica.
Published: 2023

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