467 results on '"María J. López"'
Search Results
2. Novel chimeric proteins mimicking SARS-CoV-2 spike epitopes with broad inhibitory activity
- Author
-
Mario Cano-Muñoz, Daniel Polo-Megías, Ana Cámara-Artigas, José A. Gavira, María J. López-Rodríguez, Géraldine Laumond, Sylvie Schmidt, Julien Demiselle, Seiamak Bahram, Christiane Moog, Francisco Conejero-Lara, Junta de Andalucía, Agencia Estatal de Investigación (España), Ministerio de Ciencia, Innovación y Universidades (España), European Commission, Agence Nationale de la Recherche (France), Agence Nationale de Recherches sur le SIDA et les Hépatites Virales (France), Institut Universitaire de France, and Université de Strasbourg
- Subjects
Fusion inhibitor ,COVID-19 Vaccines ,Membrane Glycoproteins ,SARS-CoV-2 ,Recombinant Fusion Proteins ,COVID-19 ,General Medicine ,Biochemistry ,Epitopes ,Viral Envelope Proteins ,Structural Biology ,Spike Glycoprotein, Coronavirus ,Humans ,Vaccine ,Molecular Biology - Abstract
SARS-CoV-2 spike (S) protein mediates virus attachment to the cells and fusion between viral and cell membranes. Membrane fusion is driven by mutual interaction between the highly conserved heptad-repeat regions 1 and 2 (HR1 and HR2) of the S2 subunit of the spike. For this reason, these S2 regions are interesting therapeutic targets for COVID-19. Although HR1 and HR2 have been described as transiently exposed during the fusion process, no significant antibody responses against these S2 regions have been reported. Here we designed chimeric proteins that imitate highly stable HR1 helical trimers and strongly bind to HR2. The proteins have broad inhibitory activity against WT B.1 and BA.1 viruses. Sera from COVID-19 convalescent donors showed significant levels of reactive antibodies (IgG and IgA) against the HR1 mimetic proteins, whereas these antibody responses were absent in sera from uninfected donors. Moreover, both inhibitory activity and antigenicity of the proteins correlate positively with their structural stability but not with the number of amino acid changes in their HR1 sequences, indicating a conformational and conserved nature of the involved epitopes. Our results reveal previously undetected spike epitopes that may guide the design of new robust COVID-19 vaccines and therapies., This work was supported by grants CV20.26565 from the Consejería de Economía y Conocimiento, Junta de Andalucía (Spain), PID2019.107515RB.C21 from the Spanish State Research Agency (SRA/10.13039/501100011033), and co-funded by ERDF/ESF, “A way to make Europe”/“Investing in your future”. The work performed in C.M.'s laboratory was supported by grants from ANRS (Agence Nationale de Recherches sur le SIDA et les hépatites virales), the Investissements d'Avenir program managed by the ANR under reference ANR-10-LABX-77 and EHVA (No. 681032, Horizon 2020). Work in S.B.'s laboratory was supported by grants from the Agence Nationale de la Recherche (ANR) (ANR-11-LABX-0070_TRANSPLANTEX), the INSERM (UMR_S 1109), the Institut Universitaire de France (IUF), all the University of Strasbourg (IDEX UNISTRA), the European Regional Development Fund (European Union) INTERREG V program (project no. 3.2 TRIDIAG) and MSD-Avenir grant AUTOGEN. We are grateful to the Spanish Radiation Synchrotron Source (ALBA), Barcelona, Spain and the European Synchrotron Radiation Facility (ESRF), Grenoble, France, for the provision of time and staff assistance at XALOC (ALBA) and ID30B and ID23-2 (ESRF) beamlines during diffraction data collection. We thank María Carmen Salinas-García for her assistance in carrying out the crystallization screenings. We also thank Pilar González-García for helping us with the statistical analysis.
- Published
- 2022
- Full Text
- View/download PDF
3. What do consumers care about when purchasing experiential packaging?
- Author
-
Paula Álvarez-González, Ana Dopico-Parada, and María J. López-Miguens
- Subjects
5311.05 Marketing (Comercialización) ,Business, Management and Accounting (miscellaneous) ,Food Science - Abstract
PurposeThe importance of packaging attributes for purchase decisions has generated interest in the research and food industry. As a matter of fact, innovation in packaging is constantly searching for new solutions that generate customer experience. The aim of this study is to analyse the effect of packaging attributes (protection, convenience, portability and storage, information, sustainability, branding and engagement) on consumer purchase intention of experiential packaging especially designed to provide an extraordinary sensory or interactive communicational experience and the influence of potential moderators.Design/methodology/approachThe authors used a quantitative methodology based on the partial least squares (PLS) technique to estimate the structural model proposed. A purposely developed questionnaire was administered to a non-probabilistic sample of 1,489 European consumers. The questionnaire included questions related to consumers' perception of packaging attributes and purchase intention of different experiential packages.FindingsThe results indicate that packaging attributes are related to consumer purchase intention of experiential packaging. Engagement attributes show the strongest positive influence followed by branding and economy. However, attributes such as sustainability showed a negative effect on the purchase intention of these packages. The authors’ results also show the influence of gender, family structure and residential background as moderators of the relationships.Originality/valueCustomers' decision-making processes are strongly influenced by product packaging. However, little is known about how new technologies and design in packaging influence consumers' responses. This research provides evidence of the influence of packaging attributes on consumer purchase intention for experiential packaging, a proliferating area of research.
- Published
- 2023
- Full Text
- View/download PDF
4. Biopriming of cucumber seeds using actinobacterial formulas as a novel protection strategy against Botrytis cinerea
- Author
-
Macarena M. Jurado, Francisca Suárez-Estrella, Ana J. Toribio, María R. Martínez-Gallardo, María J. Estrella-González, Juan A. López-González, and María J. López
- Subjects
Global and Planetary Change ,Ecology ,Horticulture ,Management, Monitoring, Policy and Law ,Agronomy and Crop Science ,Food Science - Abstract
This work highlights the ability of various actinobacterial formulas, to control the incidence of gray-mold caused by Botrytis cinerea in cucumber seedlings. Protocols applied aimed at the preliminary characterization of the actinobacterial collection and the biopolymers used as carriers were very useful for predicting their phytotoxic, phytostimulating and biopesticidal capacity. First, the phytostimulatory or phytotoxic potential of 3 biopolymers at 3 different concentrations and a collection of 10 actinobacteria were analyzed by calculating the germination index in cucumber seeds by seed dipping (biopriming). In general, two-member consortia and independent actinobacteria previously selected reached a phytostimulant effect on cucumber seedlings after their application by biopriming. Likewise, the selected actinobacteria were characterized, sole and in co-cultures, according to its ability to inhibit the growth of B. cinerea by dual culture bioassays. Finally, after selecting the most effective actinobacterial formulas, a preventive gray-mold bioassay was performed based on cucumber seed biopriming. The strains A5 and A7, in axenic and co-culture, showed to be the most efficient strains against the in vitro growth of B. cinerea. Seed biopriming strategy with actinobacterial formulas revealed a remarkable promoter effect in the early stages of plant development and after the infection with the phytopathogen fungus was remained. Definitely, the microbial formulas used in this work showed a phytostimulant and biopesticide character, laying the foundations for subsequent studies that allow a deeper scrutiny of the mechanisms of action that grant the specialization of the effect that occurs between beneficial microorganisms and specific plant hosts.
- Published
- 2023
- Full Text
- View/download PDF
5. Catalytic activity of Co–Ag nanoalloys to dissociate molecular hydrogen. New insights on the chemical environment
- Author
-
Guillermo Ortega, Estefanía Germán, María J. López, and Julio A. Alonso
- Subjects
Fuel Technology ,Renewable Energy, Sustainability and the Environment ,Energy Engineering and Power Technology ,Condensed Matter Physics - Published
- 2022
- Full Text
- View/download PDF
6. Life cycle cost assessment and economic analysis of a decentralized wastewater treatment to achieve water sustainability within the framework of circular economy
- Author
-
María J. López-Serrano, Fida Hussain Lakho, Stijn W. H. Van Hulle, and Ana Batlles-delaFuente
- Subjects
Business and Economics ,History ,Earth and Environmental Sciences ,Economics, Econometrics and Finance (miscellaneous) ,Sustainable Development Goals ,monetary evaluation ,Development ,Business and International Management ,LCCA ,wastewater ,economic analysis - Abstract
Research background: The increasing water demand together with an unceasing production of wastewater worldwide has resulted in a situation where the scarcity and pollution of water resources are jeopardizing and depleting such a vital asset. Purpose of the article: In this context, Nature Based Solutions (NBS) such as Vertical Flow Constructed Wetlands (VFCWs) are key because of their capacity of channelling a waste into a resource. However, and notwithstanding their essential role, their financial benefits too often go unnoticed because of missing research that study them from an economic perspective and this article has covered this existing gap. The objective of this research is to analyse the economic consequences of using VFCW against its traditional alternative through a comprehensive economic assessment. Methods: After doing a Life Cycle Assessment (LCA), a combination of two approaches has been carried out. This research has developed a holistic approach where a Life Cycle Cost Assessment (LCCA) based on a Cost Benefit Analysis (CBA) along with an economic evaluation of cleaning environmental costs have been calculated for two different scenarios. For this monetary analysis, the environmental externalities derived from the use of cleaning the pollution caused by a public water supply and sewerage system and the VFCW have been quantified. Findings & value added: Results conclude that VFCW apart of being a cost-effective and profitable alternative for an investor, it has also valuable benefits for the society in general because of its meaningful and positive externalities and the high removal cost of the environmental pollutants of the traditional water supply and sewage system both contributing directly to the achievement of Sustainable Development Goals (SDGs). Furthermore, 4/5 environmental impacts derived from the use of traditional alternative pollute more than twice as much as the VFCW does. Lastly, the cleaning costs difference between both alternatives is 1,984,335?.
- Published
- 2023
7. Supported metal nanohydrides for hydrogen storage
- Author
-
Estefania German, Johanna Sandoval, Adrián Recio, Abdolvahab Seif, Julio A. Alonso, and María J. López
- Subjects
Energy ,General Chemical Engineering ,Energía ,Materials Chemistry ,Física ,General Chemistry ,22 Física ,Adsorption ,Molecules ,Moléculas ,Hidrógeno ,Hydrogen ,Adsorción - Abstract
Producción Científica, Adsorption of hydrogen on graphdiyne (GDY) and boron-graphdiyne (BGDY) doped with palladium clusters has been investigated by performing density functional calculations. Pd6 fits well on the large holes of those porous layers, preserving its octahedral structure in GDY and changing it to a capped trigonal bipyramid structure in BGDY. Pd6GDY adsorbs up to five H2 molecules with sizable adsorption energies, two dissociated and three nondissociated. The dissociation barrier of H2 on the Pd6GDY cluster is 0.58 eV. Pd6BGDY can adsorb up to six molecules, three dissociated and three nondissociated, and the dissociation barrier of H2 on Pd6BGDY is 0.23 eV. In both cases, the dissociation barriers are substantially smaller than the corresponding dissociation barriers on undoped GDY and BGDY. The Pd clusters saturated with hydrogen can be viewed as nanohydrides. Spilling of the adsorbed hydrogen atoms toward the GDY and BGDY substrates is hindered by large activation barriers. We then propose using BGDY and GDY layers as support platforms for metal nanohydrides. The amount of stored hydrogen using Pd as the dopant is below the target of 6% of hydrogen in weight, but replacing Pd by a lighter metal with similar or higher affinity for hydrogen would substantially enhance the storage., Ministerio de Ciencia e Innovación (MCIN/AEI/ 10.13039/501100011033)(Grant PID2019-104924RB-I00)
- Published
- 2023
- Full Text
- View/download PDF
8. How can R&D programs induce unplanned R&D collaborative networks in clusters?
- Author
-
Isabel Díez-Vial, José Antonio Belso-Martínez, María J. López-Sánchez, and María D. Sánchez
- Subjects
Economics and Econometrics ,0502 economics and business ,05 social sciences ,Geography, Planning and Development ,0211 other engineering and technologies ,021107 urban & regional planning ,02 engineering and technology ,050203 business & management - Abstract
R&D policies are usually designed to enhance firms’ internal capabilities, but do not explicitly target R&D cooperation. In this research, we propose that R&D programs can be a suitable instrument when it comes to fostering informal collaborative networking. We focus on a regional level, the cluster, and establish that firms can use their R&D subsidies not only to become more innovative, i. e. input-output additionality, but also to develop R&D informal collaborations, i. e. behavior additionality. To test this hypothesis, relational data from a biotechnological cluster in Alicante (Spain) have been analyzed. Results from ERGM confirm that promoting internal R&D efforts prompts the formation of knowledge-based relationships at the cluster level. Policy makers should consider this unforeseen behavior when designing and evaluating non-collaborative R&D support programs. New evidence on the role of distant and diverse non-local linkages on local network dynamics is also provided.
- Published
- 2021
- Full Text
- View/download PDF
9. Tromboendarterectomía pulmonar en pacientes sintomáticos con enfermedad tromboembólica crónica sin hipertensión arterial pulmonar
- Author
-
Consuelo A. Gotor-Pérez, María J. López-Gude, Victoria Benito-Arnaiz, Jose L. Pérez-Vela, Pilar Escribano-Subías, and Jose M. Cortina-Romero
- Subjects
Surgery ,Cardiology and Cardiovascular Medicine - Published
- 2022
- Full Text
- View/download PDF
10. The Clonal Relationship Between the Ductal and Lobular Components of Mixed Ductal-Lobular Carcinomas Suggested a Ductal Origin in Most Tumors
- Author
-
Belén Pérez-Mies, Tamara Caniego-Casas, Irene Carretero-Barrio, Michele Biscuola, María A. López-García, David Hardisson, Marta Rosas, María J. López Rodríguez, Eva Cristóbal, David Pizarro, Juan M. Rosa-Rosa, and José Palacios
- Subjects
Class I Phosphatidylinositol 3-Kinases ,Carcinoma, Ductal, Breast ,Breast Neoplasms ,Catenins ,Cadherins ,Pathology and Forensic Medicine ,Carcinoma, Lobular ,Carcinoma, Intraductal, Noninfiltrating ,Humans ,Surgery ,Female ,Anatomy ,In Situ Hybridization, Fluorescence - Abstract
The relationship between the ductal and lobular components of invasive ductolobular carcinomas (IDLC) has not been fully elucidated. In this study, the molecular alterations of both components were analyzed in a series of 20 IDLC that were selected, not only by morphologic criteria, but also by the loss of E-cadherin expression in the lobular component. We found that 80% of tumors shared alterations of driver genes in both components, being PIK3CA the most common alteration. In addition, 45% of IDLC carried CDH1 mutations in their lobular component that were absent in the ductal component. Fluorescent in situ hybridization analysis of the CDH1 gene excluded homozygous CDH1 loss as a frequent cause of E-cadherin loss in tumors without CDH1 mutations. In addition, no pathogenic mutations of catenin genes were detected in this series of tumors. In 25% of tumors, actionable mutations in PIK3CA , AKT1 , and ERBB2 were found in only 1 component. Altogether, our results confirm that most IDLC derive from invasive carcinoma of no special type, in which a population of cells lose E-cadherin and acquire a lobular phenotype. The frequency of CDH1 mutations in IDLC appears to be lower than in conventional invasive lobular carcinomas, suggesting the implication of alternative mechanisms of E-cadherin loss. Moreover, molecular heterogeneity between ductal and lobular areas suggests the need for molecular characterization of both components to guide targeted therapies.
- Published
- 2022
11. Loss of PRDX6 Aborts Proliferative and Migratory Signaling in Hepatocarcinoma Cell Lines
- Author
-
Daniel J. Lagal, María J. López-Grueso, José R. Pedrajas, Thomas L. Leto, J. Antonio Bárcena, Raquel Requejo-Aguilar, and C. Alicia Padilla
- Subjects
Physiology ,Clinical Biochemistry ,Cell Biology ,redoxins ,lipid peroxidation ,mitochondrial dysfunction ,GSK3β ,epithelial–mesenchymal transition (EMT) ,Molecular Biology ,Biochemistry - Abstract
Peroxiredoxin 6 (PRDX6), the only mammalian 1-Cys member of the peroxiredoxin family, has peroxidase, phospholipase A2 (PLA2), and lysophosphatidylcholine (LPC) acyltransferase (LPCAT) activities. It has been associated with tumor progression and cancer metastasis, but the mechanisms involved are not clear. We constructed an SNU475 hepatocarcinoma cell line knockout for PRDX6 to study the processes of migration and invasiveness in these mesenchymal cells. They showed lipid peroxidation but inhibition of the NRF2 transcriptional regulator, mitochondrial dysfunction, metabolic reprogramming, an altered cytoskeleton, down-regulation of PCNA, and a diminished growth rate. LPC regulatory action was inhibited, indicating that loss of both the peroxidase and PLA2 activities of PRDX6 are involved. Upstream regulators MYC, ATF4, HNF4A, and HNF4G were activated. Despite AKT activation and GSK3β inhibition, the prosurvival pathway and the SNAI1-induced EMT program were aborted in the absence of PRDX6, as indicated by diminished migration and invasiveness, down-regulation of bottom-line markers of the EMT program, MMP2, cytoskeletal proteins, and triggering of the “cadherin switch”. These changes point to a role for PRDX6 in tumor development and metastasis, so it can be considered a candidate for antitumoral therapies.
- Published
- 2023
- Full Text
- View/download PDF
12. Seed priming by application of Microbacterium spp. strains for control of Botrytis cinerea and growth promotion of lettuce plants
- Author
-
Francisca Suárez-Estrella, Macarena M. Jurado, Juan A. López-González, Ana Toribio, María R. Martínez-Gallardo, María J. Estrella-González, and María J. López
- Subjects
Horticulture - Published
- 2023
- Full Text
- View/download PDF
13. Dual Inhibition of NF-Kb and JAK/STAT Pathways Reverts Myelofibrosis-like Phenotype in an In Vivo Murine Model
- Author
-
Ernesto J Cuenca, Pedro J Guijarro-Carrillo, María J López-Poveda, Paula Durán-Espin, Eva Soler, María Luz Morales, Maria Luisa Lozano, Alberto Alvarez-Larran, Nuria Garcia-Barbera, Rocio Gonzalez-Conejero, Constantino Martínez, Raul Teruel Montoya, and Francisca Ferrer Marin
- Subjects
Immunology ,Cell Biology ,Hematology ,Biochemistry - Published
- 2022
- Full Text
- View/download PDF
14. Type 1 Diabetes Mellitus in Pediatric Patients and Its Impact on Relationships in the Family Environment
- Author
-
María J. López, Alicia Collado Sánchez, María José Cao, Miguel Angel Madrigal, María-José Castro, and Jose María Jiménez
- Subjects
Pharmacology ,Pediatrics ,medicine.medical_specialty ,Type 1 diabetes ,business.industry ,media_common.quotation_subject ,030209 endocrinology & metabolism ,Disease ,030204 cardiovascular system & hematology ,medicine.disease ,Child health ,03 medical and health sciences ,0302 clinical medicine ,Chronic disease ,Quality of life ,Feeling ,Diabetes mellitus ,Internal Medicine ,medicine ,Self care ,business ,media_common - Abstract
Purpose The aim of this study is to assess the impact of type 1 diabetes mellitus on family environment relationships, as well as the management and approach to this disease. Patients and Methods One hundred one children, 52.47% male and 47.52% female, with an average age of 8.55 ± 4.01 years, diagnosis of type 1 diabetes mellitus. Quantitative cross-sectional descriptive study was conducted using the validated questionnaires "Modified Diabetes Quality of Life" and "Questionnaire for the assessment of psychological impact in parents/guardians of diabetic children". Results Most of the children (70.3% versus 29.7%) identified diabetes as unpleasant or not fun. The ≤5-year-olds expressed that they felt concerned about the consequences of being diabetic (8.1% by age group), as opposed to the 10-year-olds who did not feel concerned (85.1% by age group), P
- Published
- 2020
- Full Text
- View/download PDF
15. Impact of Nursing Methodology Training Sessions on Completion of the Virginia Henderson Assessment Record
- Author
-
María-José Cao, Sara Garcia, Mercedes Fernández-Castro, Manuel Frutos-Martin, María-José Castro, Jose María Jiménez, Belén Martín-Gil, and María J. López
- Subjects
education ,Nursing assessment ,Training needs - Evaluation ,Patient assessment ,Medical records - Data processing ,Article ,03 medical and health sciences ,Nursing care ,0302 clinical medicine ,Enfermería - Metodología ,Nursing ,needs assessment ,Statistical significance ,Medicine ,030212 general & internal medicine ,Training programme ,General Nursing ,Enfermería ,lcsh:RT1-120 ,lcsh:Nursing ,030504 nursing ,business.industry ,Enfermos - Cuidados y tratamiento ,Electronic records - Access control ,electronic health records ,5312.04 Educación ,Needs assessment ,Observational study ,Henderson, Virginia A. - Crítica e interpretación ,nursing care ,0305 other medical science ,business ,Inclusion (education) - Abstract
The Virginia Henderson model, integrated in the computer application GACELA Care, helps to standardise the nursing assessment and establish precise and personalised nursing diagnoses. The aim was to determine the extent of completion of the initial patient assessment record after nurses following a training programme on nursing methodology. A quasi-experimental, retrospective, randomised, observational, single-group study was performed in two stages: pre-training and post-training. Voluntary training sessions were held for the nurses that work with GACELA Care. The completion of the initial patient assessment using the needs of Virginia Henderson and the Norton scale was evaluated before and after the training sessions. Completion of the needs of Virginia Henderson in the initial patient assessment increased from 94.2% to 100% (p = 0.014). Completion of &ldquo, hygiene/skin&rdquo, increased significantly from 83.3% to 95.8% (pre-training and post-training, respectively). The remaining needs did not show statistical significance. Recording of the Norton scale increased from 63.13% to 92.5% (p <, 0.001). The training sessions on nursing methodology have improved the completion of records and inclusion of normal characteristics, defining characteristics and risk factors, and improving pressure ulcer risk assessment through the Norton scale.
- Published
- 2020
- Full Text
- View/download PDF
16. Síndrome de obesidad-hipoventilación: situación hemodinámica basal e impacto de la ventilación no invasiva
- Author
-
José Belda Ramírez, David Fole Vazquez, María J. López, Herminia Buchelli Ramirez, Gemma Rubinos Cuadrado, Ramón Fernández Álvarez, Marta Iscar Urrutia, Pere Casan Clarà, and Francisco Rodriguez Jerez
- Subjects
Pulmonary and Respiratory Medicine ,Obesity hypoventilation syndrome ,medicine.medical_specialty ,Cardiac output ,business.industry ,Cardiac index ,Hemodynamics ,medicine.disease ,03 medical and health sciences ,0302 clinical medicine ,030228 respiratory system ,Internal medicine ,Heart failure ,medicine ,Breathing ,Cardiology ,Risk factor ,business ,End-systolic volume - Abstract
Introduction Obesity-hypoventilation syndrome (OHS) is a risk factor for heart failure (HF). Some studies associate the use of non-invasive ventilation (NIV) with changes in hemodynamic parameters. Our objective was to describe the hemodynamic status of a group of patients with OHS and to study the effect of NIV. Patients and methods Patients with stable OHS treated with NIV were included in this cross-sectional repeated measurements study. Hemodynamics were measured by bioimpedance: 30 min at baseline and another 30 min on NIV. Cardiac output (CO), cardiac index, and systolic volume were measured. The CO calculated for each patient expressed as a percentage of the lower limit of normal (LLN) was taken as reference, and 2 groups were formed: patients without HF and normal CO (≥100% of LLN) and patients with HF and low CO ( Results The final sample comprised 36 patients, aged 66 (±8) years, 19 (52%) men. In 17 (46%) patients, HF was detected with a CO of 3.7 l/min (66%) compared to the group without HF, whose CO was 7 l/min (107%). After NIV, patients with HF showed improvement in CO 4.5 l/min (77%), P=.009, while the non-HF group remained unchanged, with CO 6.8 l/min (104%), P=.2. Conclusion A total of 46% of patients with stable OHS present HF; NIV improves hemodynamics and does not affect patients with normal CO.
- Published
- 2020
- Full Text
- View/download PDF
17. Short-Term Changes on Body Composition and Bone Mass After One-Anastomosis Gastric Bypass: a Prospective Observational Study
- Author
-
Jaime Ruiz-Tovar, María J. López, Maria J. Castro, Artur Marc-Hernández, Miguel A. Carbajo, José Manuel Olías Jiménez, and Maria J. Cao
- Subjects
medicine.medical_specialty ,Nutrition and Dietetics ,business.industry ,Endocrinology, Diabetes and Metabolism ,medicine.medical_treatment ,Gastric bypass ,Urology ,030209 endocrinology & metabolism ,Anastomosis ,Fat mass ,03 medical and health sciences ,0302 clinical medicine ,Weight loss ,Medicine ,030211 gastroenterology & hepatology ,Surgery ,Observational study ,medicine.symptom ,business ,Bioelectrical impedance analysis ,Reduction (orthopedic surgery) ,Bone mass - Abstract
Bariatric surgery generates a large weight loss. It is considered a successful surgery when 50% of the excess weight loss is reached. However, this measure does not include some variables that may have a direct impact on a patient’s health, such as fat-free mass (FFM) or bone mass. Therefore, the aim of this study is to evaluate body composition and bone mass in patients undergoing one-anastomosis gastric bypass (OAGB). A prospective observational study was performed in patients undergoing OAGB. Body composition and bone mass were evaluated by bioelectrical impedance analysis at baseline (1 day prior to surgery), at 6 and 12 months after surgery. A total of 94 patients (67% females and 33% males) were included in the study. The excess BMI loss at 6 and 12 months after surgery was 97.9 ± 20.1% and 110.2 ± 30.5% respectively. The FFM showed a reduction of 6.6 ± 4.8 kg (p
- Published
- 2020
- Full Text
- View/download PDF
18. Adherencia al ejercicio físico en mujeres tras completar un programa de rehabilitación cardiaca
- Author
-
Joaquín Domínguez Paniagua, Estrella Barreñada Copete, Cristina María Artiles León, Javier Botas Rodríguez, Elia Pérez Fernández, Raquel Campuzano Ruiz, and María J. López Navas
- Subjects
Cardiology and Cardiovascular Medicine - Abstract
Resumen Introduccion y objetivos La eficacia de la rehabilitacion cardiaca (RC) se basa en controlar los factores de riesgo cardiovascular y lograr adherencia al ejercicio fisico y a un estilo de vida saludable. Se han descrito diferencias por genero en la practica de ejercicio fisico tras la RC, peor en las mujeres, probablemente por las diferencias en sus roles sociales. El objetivo del presente trabajo fue estudiar la adherencia al ejercicio fisico a largo plazo de las mujeres que completaron un programa de RC (PRC) y los factores que influyen en ella. Metodos Se selecciono a 99 mujeres que completaron el PRC desde 2013 hasta 2018. Se evaluaron, mediante un cuestionario basado en el de EUROASPIRE V, variables psicosociales, antropometricas y analiticas. Resultados De las 99 mujeres incluidas en el estudio, 84 (84%; IC95%, 76,5-90,6) afirmaron continuar practicando ejercicio fisico regular. El tiempo transcurrido desde la finalizacion de la RC, estar al cuidado de un familiar o ser laboralmente activas no supuso una barrera en la adherencia al ejercicio de las pacientes del estudio (p > 0,05). Aquellas asesoradas periodicamente por profesionales sanitarios (82%) fueron mas constantes en la practica de ejercicio fisico regular. Conclusiones La adherencia al ejercicio fisico en mujeres tras el PRC en nuestro centro continua siendo muy elevada: 84% y sin decaer en el tiempo. Dicha adherencia no esta influida por factores psicosociales o el paso del tiempo y es mejor en aquellas pacientes que reciben asesoramiento sobre actividad fisica del profesional sanitario.
- Published
- 2020
- Full Text
- View/download PDF
19. Measurement of upper airway resistances: A simple way to assess its collapsibility?
- Author
-
Julia Herrero Huertas, Gemma Rubinos Cuadrado, Pere Casan Clarà, María J. López, Marta Iscar Urrutia, and Ramón Fernández Álvarez
- Subjects
Male ,medicine.medical_specialty ,Supine position ,Polysomnography ,Positive correlation ,Severity of Illness Index ,Airway resistance ,Internal medicine ,Humans ,Medicine ,Sleep Apnea, Obstructive ,business.industry ,Nocturnal polysomnography ,Airway Resistance ,Middle Aged ,medicine.disease ,respiratory tract diseases ,Clinical Practice ,Obstructive sleep apnea ,Cross-Sectional Studies ,ROC Curve ,Otorhinolaryngology ,Cardiology ,Female ,Neurology (clinical) ,Airway ,business - Abstract
The collapsibility of the upper airway is a key factor in the pathogenesis of obstructive sleep apnea (OSA). The exact measurement of this parameter, typically performed by obtaining the critical pressure (Pcrit), has not been introduced into clinical practice. The techniques that are used to measure the upper airway resistance could provide information on its the collapsibility of the airway. The aim of this study was to associate resistance in the upper airway with the presence of OSA. Using a cross-sectional design with a control group, consecutive cases that were seen in the Chest Diseases Sleep Unit were recruited after undergoing nocturnal polysomnography. The upper airway collapsibility was determined based on the change in its resistance from the standing position to the supine position with a flow interruption (Rint) device by measuring the angle formed between the pressure/flow lines (PF angle) between the two positions. The PF angle was greater in the OSA group than in the controls: 7.5° (4) vs. 4° (2) (P
- Published
- 2020
- Full Text
- View/download PDF
20. Palladium clusters, free and supported on surfaces, and their applications in hydrogen storage
- Author
-
Julio A. Alonso and María J. López
- Subjects
General Physics and Astronomy ,Physical and Theoretical Chemistry - Abstract
Palladium is a late transition metal element in the 4d row of the periodic table. Palladium nanoparticles show efficient catalytic activity and selectivity in a number of chemical reactions. In this paper, we review the structural and electronic properties of palladium nanoclusters, both isolated and deposited on the surface of different substrates. Careful experiments and extensive calculations have been performed for small Pd clusters which provide ample information on their properties. Work on large Pd clusters is less abundant and more difficult to perform and interpret. Cluster deposition is a method to modify material surfaces for different applications, and we report the known results for the deposition of Pd clusters on the surfaces of a number of interesting substrates: carbonaceous substrates like graphene and some layered novel materials related to graphene, metal oxide substrates, silicon and silicon-related substrates and metallic alloy substrates. Emphasis is placed on revealing how the structural, electronic and magnetic properties change when the clusters are deposited on the substrate surfaces. Some examples of chemical reactions catalyzed by supported Pd clusters and nanoparticles are reported. An issue discussed in detail is the influence of Pd on the storage of hydrogen in porous materials. Experimental work shows that the amount of stored hydrogen increases when the absorbing material is doped with Pd atoms, clusters and nanoparticles, and a spillover mechanism from the metal particle to the substrate is usually accepted as the explanation. To shed light on this issue, a critical analysis based on density functional simulations of the mechanisms of hydrogen spillover in perfect and defective graphene doped with palladium clusters is presented.
- Published
- 2022
21. The Effects of Agricultural Plastic Waste on the Vermicompost Process and Health Status of Eisenia fetida
- Author
-
José A. Sáez, Angie M. Pedraza Torres, Zbigniew Emil Blesa Marco, Francisco Javier Andreu-Rodríguez, Frutos C. Marhuenda-Egea, Encarnación Martínez-Sabater, María J. López, Francisca Suarez-Estrella, and Raúl Moral
- Subjects
Eisenia fetida ,agricultural plastic waste ,vermicomposting ,ecotoxicology ,earthworm ,Agronomy and Crop Science - Abstract
Nowadays, plastic materials are extensively used in the agri-food sector for multiple purposes. The end-of-life management of these plastics is an environmental challenge because frequent incomplete recoveries after the crop seasons lead to the accumulation of plastics debris in agricultural waste, which is now recognized as an emerging environmental issue of global concern. However, the effects of plastic debris in agricultural waste undergoing biotreatment have been poorly studied. This study assesses the effects of agricultural plastic waste (APW) (LDPE + LLDPE and EPS) (1.25% f.w.) on the vermicomposting process (45 days) in terms of earthworm health by measuring biomarker responses and the enzymatic activity and quality/stabilization of the vermicompost obtained. The results showed that exposure to all the plastic materials tested had negative morphological effects on earthworm survival and body biomass. In the vermicomposting process, the changes detected in the enzymatic activity of the vermicompost and the biofilm seemed to affect the degradation rate of earthworms and the microbiome of the substrate, as demonstrated by the low organic matter mineralization in the vermicompost exposed to plastic. Although no significant changes were recorded in several biomarkers, signs of oxidative stress were evidenced throughout the glutathione S-transferase and carboxylesterase activity, mainly involving balanced oxidative stress and xenobiotic resistance systems.
- Published
- 2022
22. Farmers’ Attitudes towards Irrigating Crops with Reclaimed Water in the Framework of a Circular Economy
- Author
-
Juan Francisco Velasco Muñoz, José Ángel Aznar Sánchez, María J. López-Serrano, and I.M. Román-Sánchez
- Subjects
sustainable agriculture ,reclaimed water ,tertiary water ,treated wastewater ,circular economy ,perceptions ,farmers ,Agronomy and Crop Science - Abstract
In a global situation where water constraints are a daily concern and expected to worsen in the upcoming years, finding new water alternatives to guarantee its supply is of critical importance. Against this background, reclaimed water has proved to be a sustainable alternative that recycles wastewater from a circular economy approach, thus enhancing water availability for key sectors such as agriculture. In such a context where public policies should encourage the implementation of this sustainable resource that helps reduce climate change by allowing wastewater reuse, there is too often a lack of knowledge of farmers’ perceptions, thus resulting in them being ineffective. In this sense, studying and analyzing agriculturalists’ perceptions is of interest for the development of appropriate policies that truly foster reclaimed water use in agriculture and enhance its shift from waste to resource. For this research 231 farmers, both long-time users of reclaimed water and non-users, were surveyed to find common and differing attitudes and perceptions. Results show how once farmers start irrigating their crops with this alternative resource there is a marked improvement in their opinion. The high price is the most widespread barrier, which can be tempered with public subsidies that absorb part of this cost. The insights obtained from this research may be of interest to other regions, especially for those in arid and semi-arid climates where water scarcity is a critical problem and sustainability a growing concern.
- Published
- 2022
23. Infrared spectra and structures of C60Rhn+ complexes
- Author
-
Estefania German, Gao-Lei Hou, Jan Vanbuel, Joost M. Bakker, Julio A. Alonso, Ewald Janssens, and María J. López
- Subjects
GRAPHENE ,Technology ,Rodio ,ADSORPTION ,Materials Science ,Materials Science, Multidisciplinary ,CATALYSTS ,DFT ,CARBON NANOTUBES ,Fullerene ,IRMPD ,General Materials Science ,Rhodium ,H-2 ,FELIX Condensed Matter Physics ,Science & Technology ,SPECTROSCOPY ,Chemistry, Physical ,Fullereno ,D-2-tagged ,General Chemistry ,METAL-SUPPORT INTERACTIONS ,C60 ,Chemistry ,Physical Sciences ,Fullerenes ,C-60 - Abstract
Producción Científica, Metal clusters supported on carbonaceous substrates are of interest in catalysis, hydrogen storage, and other fields. In this paper, the structures and the infrared spectra of C60Rhn+ (n = 1–6) fullerene-metal complexes are studied by a combination of mass-selective infrared spectroscopy and theoretical calculations. It is found that clustering of Rh on the surface of the fullerene is preferred over surface wetting. For Rh4+ and Rh6+, the structures of the adsorbed clusters are different from those of the free clusters. There is electron transfer from the metal cluster to the fullerene in neutral C60Rhn, and in cationic C60Rhn+ the electron deficit is shared by the metal cluster and the fullerene. Adsorption of Rhn clusters leads to degeneracy lifting of the most intense C60 features in the infrared spectra that were measured in the 300–850 cm−1 range. Agreement is obtained, in general, between the experimental infrared spectra of D2-tagged C60Rhn+ and the calculated spectra for untagged C60Rhn+, except in the 600–750 cm−1 region, where features mainly arise from the presence of D2-messenger molecules adsorbed on the Rhn clusters., Junta de Castilla y Leon (grant VA021G18), Ministerio de Ciencia, Innovación y Universidades (grant PID2019-104924RB-I00), KU Leuven Research Council (grant C14/18/073), Barcelona Supercomputing Center (grants FI-2019-3-0029 and FI-2020-1-0032)
- Published
- 2022
24. Sustainability: The Role of Spiritual Capital, Transformational Leadership and Effectuation
- Author
-
Juan M. Gil-Barragan, María J. López-Sánchez, and Andrés Aguilera-Castillo
- Subjects
Organizational Behavior and Human Resource Management ,Strategy and Management ,Religious studies ,Social Sciences (miscellaneous) - Abstract
This study contributes to the sustainability literature by conceptualizing how the individual and collective identities (in terms of spiritual capital and transformational leadership) interact with the sub-dimensions of effectual orientation to achieve sustainable performance. This article uses a sample of 52 cases to analyze the empirical data. Using a fuzzy-set qualitative comparative analysis (fsQCA), this article aims to explore some of the complexities underlying sustainable performance. The analysis demonstrates that effectual orientation, spiritual capital, and transformational leadership are important but not sufficient to achieve sustainable performance; rather, it is their interaction that leads to this outcome. Moreover, despite the differences of the firm’s resource constraints, the combination of effectual orientation, spiritual capital, and transformational leadership enhance social entrepreneurship.
- Published
- 2022
- Full Text
- View/download PDF
25. Characteristics of gastric cancer around the world
- Author
-
María J, López, Junior, Carbajal, Alejandro L, Alfaro, Luis G, Saravia, Daniel, Zanabria, Jhajaira M, Araujo, Lidia, Quispe, Alejandra, Zevallos, José L, Buleje, Cristina Eunbee, Cho, Marisol, Sarmiento, Joseph A, Pinto, and Williams, Fajardo
- Subjects
Oncology ,Hematology - Abstract
Gastric cancer is one of the most important malignancies in the world due to the high burden of disease and lethality. In this work, we compared the main characteristics of gastric cancer between different regions of the world. We reviewed public repositories to retrieve epidemiological, molecular, clinicopathological, and risk factor data. Eastern Asia presents the highest incidence of gastric cancer, followed by eastern and central Europe. Intestinal histology was more frequent in Caucasians, while gastric tumors located in the cardias were less frequent in Africa and Latin America. TP53, LRP1B, and ARID1A are consistently the most frequently altered genes in all population groups. Gastric cancer is most frequent in men. African patients tend to be younger and have a higher proportion of women patients. Different patterns can be observed in the presentation of gastric cancer between different regions of the world. More research is needed in Latin America and Africa since these populations are underrepresented.
- Published
- 2023
- Full Text
- View/download PDF
26. Industrial Composting of Sewage Sludge: Study of the Bacteriome, Sanitation, and Antibiotic-Resistant Strains
- Author
-
Juan A. López-González, María J. Estrella-González, Rosario Lerma-Moliz, Macarena M. Jurado, Francisca Suárez-Estrella, and María J. López
- Subjects
Microbiology (medical) ,metagenomics ,compost ,antibiotic resistance ,biosolids ,fecal contamination ,clostridia ,Microbiology ,QR1-502 ,enterobacteria ,fecal enterococci ,Original Research - Abstract
Wastewater treatment generates a huge amount of sewage sludge, which is a source of environmental pollution. Among the alternatives for the management of this waste, industrial composting stands out as one of the most relevant. The objective of this study was to analyze the bacterial population linked to this process and to determine its effectiveness for the reduction, and even elimination, of microorganisms and pathogens present in these organic wastes. For this purpose, the bacteriome and the fecal bacteria contamination of samples from different sewage sludge industrial composting facilities were evaluated. In addition, fecal bacteria indicators and pathogens, such as Salmonella, were isolated from samples collected at key stages of the process and characterized for antibiotic resistance to macrolide, β-lactam, quinolone, and aminoglycoside families. 16S rRNA phylogeny data revealed that the process clearly evolved toward a prevalence of Firmicutes and Actinobacteria phyla, removing the fecal load. Moreover, antibiotic-resistant microorganisms present in the raw materials were reduced, since these were isolated only in the bio-oxidative phase. Therefore, industrial composting of sewage sludge results in a bio-safe final product suitable for use in a variety of applications.
- Published
- 2021
- Full Text
- View/download PDF
27. Length Absence of Spillover of Hydrogen Adsorbed on Small Palladium Clusters Anchored to Graphene Vacancies
- Author
-
Alejandra Granja-DelRío, Maite Alducin, María J. López, J. Iñaki Juaristi, Julio A. Alonso, Universidad del País Vasco, Eusko Jaurlaritza, Ministerio de Ciencia e Innovación (España), Junta de Castilla y León, and Universidad de Valladolid
- Subjects
General Physics and Astronomy ,chemistry.chemical_element ,02 engineering and technology ,dissociation ,surfaces ,010402 general chemistry ,hydrogen spillover ,01 natural sciences ,Hydrogen adsorption ,hydrogen storage ,nanotubes ,Ab initio molecular dynamics ,storage capacity ,graphene vacancies ,activated carbon-fibers ,spheres ,Physics ,hydrogen adsorption ,atoms ,Surfaces and Interfaces ,General Chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,simulation ,0104 chemical sciences ,Surfaces, Coatings and Films ,chemistry ,adsorption ,hydrogenated palladium ,Hydrogen spillover ,0210 nano-technology ,Humanities ,Palladium - Abstract
Experimental evidence exists for the enhancement of the hydrogen storage capacity of porous carbons when these materials are doped with metal nanoparticles. One of the most studied dopants is palladium. Dissociation of the hydrogen molecules and spillover of the H atoms towards the carbon substrate has been advocated as the reason for the enhancement of the storage capacity. We have investigated this mechanism by performing ab initio density functional molecular dynamics (AIMD) simulations of the deposition of molecular hydrogen on Pd6 clusters anchored on graphene vacancies. The clusters are initially near-saturated with atomic and molecular hydrogen. This condition would facilitate the occurrence of spillover, since our energy calculations based on density functional theory indicate that migration of preadsorbed H atoms towards the graphene substrate becomes exothermic on Pd clusters with high hydrogen coverages. However, AIMD simulations show that the H atoms prefer to intercalate and absorb within the Pd cluster rather than migrate to the carbon substrate. These results reveal that high activation barriers exist preventing the spillover of hydrogen from the anchored Pd clusters to the carbon substrate., The authors acknowledge financial support by the Gobierno Vasco-UPV/EHU Project No. IT1246-19, the Spanish Ministerio de Ciencia e Innovación [Grants No. PID2019-107396 GB-I00/AEI/10.13039/501100011033 and PID2019-104924RB-I00], Junta de Castilla y León [Grant VA021G18], and University of Valladolid (Grupo de Física de Nanoestructuras). A. G. acknowledges a predoctoral fellowship from Junta de Castilla y León.
- Published
- 2021
28. Characterization of Thermophilic Lignocellulolytic Microorganisms in Composting
- Author
-
María J. Estrella-González, J.A. López-González, Maria R. Martínez-Gallardo, A.J. Toribio, M.M. Jurado, Francisca Suárez-Estrella, and María J. López
- Subjects
Microbiology (medical) ,Firmicutes ,Population ,Cellulase ,ligninases ,complex mixtures ,Microbiology ,thermotolerance ,Actinobacteria ,laccase ,chemistry.chemical_compound ,Hemicellulose ,Food science ,education ,Original Research ,education.field_of_study ,xylanase ,cellulase ,lignin peroxidase ,biology ,Thermophile ,fungi ,Lignin peroxidase ,culturome ,biology.organism_classification ,QR1-502 ,chemistry ,biology.protein ,Xylanase - Abstract
Composting involves the selection of a microbiota capable of resisting the high temperatures generated during the process and degrading the lignocellulose. A deep understanding of the thermophilic microbial community involved in such biotransformation is valuable to improve composting efficiency and to provide thermostable biomass-degrading enzymes for biorefinery. This study investigated the lignocellulose-degrading thermophilic microbial culturome at all the stages of plant waste composting, focusing on the dynamics, enzymes, and thermotolerance of each member of such a community. The results revealed that 58% of holocellulose (cellulose plus hemicellulose) and 7% of lignin were degraded at the end of composting. The whole fungal thermophilic population exhibited lignocellulose-degrading activity, whereas roughly 8–10% of thermophilic bacteria had this trait, although exclusively for hemicellulose degradation (xylan-degrading). Because of the prevalence of both groups, their enzymatic activity, and the wide spectrum of thermotolerance, they play a key role in the breakdown of hemicellulose during the entire process, whereas the degradation of cellulose and lignin is restricted to the activity of a few thermophilic fungi that persists at the end of the process. The xylanolytic bacterial isolates (159 strains) included mostly members of Firmicutes (96%) as well as a few representatives of Actinobacteria (2%) and Proteobacteria (2%). The most prevalent species were Bacillus licheniformis and Aeribacillus pallidus. Thermophilic fungi (27 strains) comprised only four species, namely Thermomyces lanuginosus, Talaromyces thermophilus, Aspergillus fumigatus, and Gibellulopsis nigrescens, of whom A. fumigatus and T. lanuginosus dominated. Several strains of the same species evolved distinctly at the stages of composting showing phenotypes with different thermotolerance and new enzyme expression, even not previously described for the species, as a response to the changing composting environment. Strains of Bacillus thermoamylovorans, Geobacillus thermodenitrificans, T. lanuginosus, and A. fumigatus exhibiting considerable enzyme activities were selected as potential candidates for the production of thermozymes. This study lays a foundation to further investigate the mechanisms of adaptation and acquisition of new traits among thermophilic lignocellulolytic microorganisms during composting as well as their potential utility in biotechnological processing.
- Published
- 2021
- Full Text
- View/download PDF
29. Transferability in interatomic potentials for carbon
- Author
-
Daniel J. Lim, Jake L. Jones, Irene Suarez-Martinez, Carla de Tomas, Alireza Aghajamali, María J. López, and Nigel A. Marks
- Subjects
Diffraction ,Materials science ,Transferability ,chemistry.chemical_element ,02 engineering and technology ,General Chemistry ,Radial distribution ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,Characterization (materials science) ,Molecular dynamics ,Amorphous carbon ,chemistry ,Chemical physics ,General Materials Science ,0210 nano-technology ,Carbon - Abstract
Interatomic potentials underpin many atomistic simulations and great effort is devoted to develop and benchmark potentials. In 2016 [Carbon 109, 681–693], we tested six common carbon potentials and compared their ability to describe disordered carbon structures. Here, we expand this study with eight additional potentials: AIREBO, REBO2-S, Erhart/Albe, ABOP, GAP, Tersoff-S, Tersoff/Nordlund and Tersoff with modified cutoff. Using molecular dynamics we produce and anneal amorphous carbon structures of different densities. Characterization using coordination analysis, ring statistics, radial distribution functions and diffraction intensity show that no two potentials give the same result. To address this lack of transferability, we have developed a web application tool, www.carbonpotentials.org which collates all carbon potentials and enables real-time and equivalent comparison. Unlike a traditional publication that is frozen in time, the tool is expandable and can accommodate new potentials and data.
- Published
- 2019
- Full Text
- View/download PDF
30. The ‘Deadly Secret’ of the Prophecy: Performative and Parabolic Language in Chigozie Obioma’s The Fishermen
- Author
-
María J. López
- Subjects
biology ,Philosophy ,media_common.quotation_subject ,Miller ,Performative utterance ,Ambiguity ,biology.organism_classification ,Witness ,Literal and figurative language ,Epistemology ,Action (philosophy) ,Argument ,Impossibility ,media_common - Abstract
In Chigozie Obioma’s novel, The Fishermen (2015), we witness the tragic events triggered by a prophecy delivered to four Nigerian brothers. My main aim in this essay is, following J. Hillis Miller’s analysis of speech acts in literature, and also ideas by Jacques Derrida and Derek Attridge, to develop an argument about this prophecy as a performative use of words that makes things happen in the world by way of its listeners and believers. The prophecy is presented as a speech act characterised by secrecy, obscurity and ambiguity, given the impossibility of subjecting its words to true and false verification and its undecidability in relation to the literal and the figurative uses of language. It is a speech act that requires an addressee that literally and naively believes in it, with Ikenna–the oldest brother–emerging as such a believer, who in this sense is just like his siblings, repeatedly presented as taking language at face value, unable to recognize its duplicitous and ambivalent nature. Because of this inability to perceive the parabolic or indirect dimension of language, the children establish a continuity between language and action, which leads them to act on reality led by words, in all cases with fatal consequences.
- Published
- 2019
- Full Text
- View/download PDF
31. Moving in 'a forest of hieroglyphs': Enigmatic and mutable signs of identity in Zoë Wicomb’sPlaying in the Light
- Author
-
María J. López
- Subjects
Literature and Literary Theory ,Aesthetics ,media_common.quotation_subject ,Identity (social science) ,Art ,media_common - Abstract
This article analyses Zoe Wicomb’s Playing in the Light, focusing on protagonist Marion’s process of coming to terms with her coloured identity as she puzzles over secrets and signs, strugg...
- Published
- 2019
- Full Text
- View/download PDF
32. Dynamics of Cluster Isomerization Induced by Hydrogen Adsorption
- Author
-
Alejandra Granja-DelRío, Maite Alducin, María J. López, Julio A. Alonso, J. Iñaki Juaristi, Juaristi Oliden, Joseba Iñaki, López, María J., Juaristi Oliden, Joseba Iñaki [0000-0002-4208-8464], and López, María J. [0000-0001-7698-9327]
- Subjects
Materials science ,Ab initio ,Physics::Optics ,02 engineering and technology ,010402 general chemistry ,01 natural sciences ,Hydrogen adsorption ,law.invention ,Condensed Matter::Materials Science ,law ,Vacancy defect ,Physics::Atomic and Molecular Clusters ,Physics::Atomic Physics ,Physics::Chemical Physics ,Physical and Theoretical Chemistry ,Graphene ,Hydrogen molecule ,021001 nanoscience & nanotechnology ,0104 chemical sciences ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,Formalism (philosophy of mathematics) ,General Energy ,Chemical physics ,0210 nano-technology ,Isomerization - Abstract
Ab initio dynamical simulations based on the density functional formalism have been performed for molecular hydrogen impinging on a Pd cluster anchored to a vacancy defect in graphene. Under the conditions assumed in the simulations, most H molecules rebound after colliding with the Pd cluster, but a number of molecules stay adsorbed on its surface. Depending on whether the substrate is initially at 0 or 300 K, either one-third or one-half of those adsorbed molecules later on dissociate on the cluster, leading to two chemisorbed H atoms. For both substrate temperatures, dissociation of H triggers a transition from the original octahedral structure of the anchored Pd to an incomplete pentagonal bypiramid structure, which is essentially produced by a severe elongation of the distance between two particular neighbor Pd atoms. Interestingly, no such structural changes were previously observed for Pd adsorbed on pristine graphene. Although this new result comes for a specific reaction - this one occurring, for instance, in the anode of hydrogen fuel cells - we anticipate that the observation of a structural change, which means that the cluster structure is not immune to the reaction taking place on its surface, can be relevant for many catalytic processes occurring on the surface of small metal particles.
- Published
- 2019
- Full Text
- View/download PDF
33. Pottery Covered in Mud: Data of some Vessels of the Second Intermediate Period/New Kingdom Found inside Tomb QH33 at Qubbet el-Hawa, Assuan
- Author
-
María J. López-Grande
- Subjects
ofrendas ,jarras de almacenamiento ,Dinastía XVIII temprana ,Reino Nuevo temprano ,Cubriciones de barro ,necrópolis - Abstract
espanolLos trabajos arqueologicos realizados en la tumba QH33 de Qubbet el-Hawa (Asuan, Egipto) bajo la direccion del Dr. Alejandro Jimenez-Serrano (Universidad de Jaen) han documentado diversos recipientes ceramicos que presentan abundantes restos de barro en su superficie externa. Este lodo negro, derivado del limo del Nilo, parece indicar que, previamente a su colocacion en la tumba, estas vasijas fueron cubiertas de manera intencionada con una densa capa de lodo que las envolvia completamente. Los recipientes en los que se ha constatado esta practica son de grandes dimensiones. Su enorme tamano y otros detalles de su morfologia y materia prima sugieren que pudieron estar destinados a transportar y/o almacenar ofrendas. La practica de cubrir con barro enteramente y de manera intencionada las vasijas ceramicas no esta ampliamente documentada en epoca faraonica o, al menos, apenas ha sido dada a conocer hasta la fecha. En la amplia bibliografia consultada hemos detectado algunos ejemplos que, por lo general, estan referidos a vasijas en las que el barro se ha aplicado parcialmente, en la zona de la boca del vaso, para facilitar su precintado. Este articulo presenta los tipos ceramicos documentados hasta la fecha en la tumba QH33 de Qubbet el-Hawa que muestran la peculiaridad de haber estado cubiertos en su totalidad de barro. Avanza las hipotesis interpretativas que hasta ahora han sido exploradas para abordar el sentido de estas llamativas cubriciones, basadas en los escasos paralelos arqueologicos documentados y en datos etnograficos y antropologicos. Presenta, ademas, algunas valoraciones y propuestas sobre el uso del barro en relacion a los recipientes ceramicos en el Egipto faraonico. EnglishArchaeological research carried out at Qubbet el-Hawa (Aswan, Egypt), led by Dr Alejandro Jimenez Serrano (University of Jaen, Spain), has brought to light some pottery vessels with abundant remains of mud bonded to their outer surfaces. The thickness of this mud, spread over the whole body of the vases, seems to indicate that these pots were intentionally covered in mud before being placed inside the tomb. All the vessels found with this peculiarity are large jars. Their sizes as well as other details related to their shapes and raw materials suggest that they were intended to transport and/or store offerings. The practice of intentionally covering the entire outer surface of large pottery vessels in mud is not widely attested in pharaonic times. The consulted bibliography offers examples of pots partially covered in mud, mainly restricting the area to the pot’s mouth in order to facilitate its sealing. This article presents the pottery types covered in mud found inside Tomb QH33. It advances some interpretative hypotheses that have been explored in order to gain an understanding of this practice. These are based on some few archaeological parallels as well as on ethnographic and anthropological data. It also presents some proposals on the use of mud in connection with ceramics in Pharaonic Egypt.
- Published
- 2019
- Full Text
- View/download PDF
34. Bimetallic Al–Sn clusters: mixing at the nanoscale
- Author
-
Alvaro Donís, María J. López, and Julio A. Alonso
- Subjects
education.field_of_study ,Materials science ,Population ,Condensation ,General Physics and Astronomy ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Miscibility ,0104 chemical sciences ,Chemical physics ,Phase (matter) ,Atom ,Mass spectrum ,Cluster (physics) ,Physical and Theoretical Chemistry ,0210 nano-technology ,education ,Bimetallic strip - Abstract
Metals which are not miscible in the bulk solid phase can form clusters at the nanoscale, and a typical example is the Al-Sn system. We have investigated the reasons for the enhanced miscibility occurring at the nanoscale. Density functional calculations have been performed for small AlmSnn clusters at all compositions when the total number of atoms N = m + n is equal to or smaller than N = 6, and for selected compositions for N = 10 and N = 11. The cohesive energies show that the clusters are energetically stable with respect to the separated atoms. Also, after an AlmSnn cluster has formed, its separation into two pure clusters Alm and Snn is energetically forbidden. This justifies the observation that those clusters can form by condensation in gas phase experiments. The different miscibility criteria explored reveal a substantial dependence on the reference state. Between those miscibility criteria, a particularly valuable one consists in studying the substitution reactions in which an Al atom of the gas replaces a Sn atom of the AlmSnn cluster to produce Alm+1Snn-1, or a Sn atom replaces an Al atom to produce Alm-1Snn+1. The conclusion is that substitution reactions enriching the clusters in Sn and depleting the cluster in Al are favorable. However, AlSn10 is an exception to this general trend. This is a special cluster. It readily forms by replacing a Sn atom by an Al atom in Sn11. Also, AlSn10 forms easily by adding an Al atom to Sn10. The geometric structures of Sn11 and Sn10 easily reorganize to form AlSn10 accommodating the Al atom inside a Sn cage. The exceptionally stable character of AlSn10 justifies the identification of AlSn10 as a magic cluster with the highest population in the measured mass spectra of this family. Even if Al and Sn can form clusters, the degree of mixing of these two elements in the clusters is modest, and a tendency for segregation of Al and Sn atoms on different parts of the cluster is incipient.
- Published
- 2019
- Full Text
- View/download PDF
35. C60Con complexes as hydrogen adsorbing materials
- Author
-
Ewald Janssens, María J. López, Julio A. Alonso, and Estefania German
- Subjects
Technology ,Fullerene ,Energy storage ,ADSORPTION ,Hydrogen ,Energy & Fuels ,Dimer ,NANOTUBES ,Energy Engineering and Power Technology ,chemistry.chemical_element ,02 engineering and technology ,010402 general chemistry ,Photochemistry ,01 natural sciences ,Dissociation (psychology) ,chemistry.chemical_compound ,symbols.namesake ,Adsorption ,medicine ,Electrochemistry ,Molecule ,SPILLOVER ,H-2 ,Science & Technology ,PORE-SIZE ,Renewable Energy, Sustainability and the Environment ,Chemistry ,Chemistry, Physical ,fullerene ,CARBIDE-DERIVED CARBONS ,Cobalt ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,0104 chemical sciences ,Fuel Technology ,MOLECULAR-HYDROGEN ,Physical Sciences ,symbols ,Density functional theory ,van der Waals force ,medicine.symptom ,0210 nano-technology ,CLUSTERS ,FIBERS ,STORAGE - Abstract
An active line of contemporary research is dedicated to the adsorption and storage of hydrogen on metal-doped carbon materials. Using density functional theory and van der Waals corrections we have studied molecular and dissociative adsorption of H2 on neutral and cationic C60Con complexes with n = 1–8. The Co atoms form compact clusters on the surface of the fullerene. Dissociative chemisorption of one H2 molecule is more stable than molecular adsorption on neutral C60Con, with the only exception of C60Co. When C60Con is ionized, the electronic charge deficit remains localized in the cobalt cluster. The molecular and dissociative adsorption features on cationic C60Con+ and neutral C60Con complexes are in general similar, but some differences can be highlighted. Molecular and dissociative H2 adsorption on C60Co2+ are competitive; in fact, molecular adsorption is slightly more stable as a result of the localized electronic charge deficit on the Co dimer. Another difference is that the dissociative adsorption energies on some of the neutral C60Con complexes are substantially larger than the dissociative adsorption energies on the corresponding C60Con+ cationic complexes by amounts between 0.2 and 0.5 eV. Activation barriers for dissociation of the adsorbed H2 molecule strongly depend on the charge state and cluster size. These barriers help to interpret the adsorption state (molecular or dissociated) of experimentally produced hydrogenated C60Con+ complexes. Hydrogen saturation has been studied in two cases. C60Co adsorbs three H2 units in molecular form, and C60Con adsorbs up to thirteen H2 units, four dissociated and nine in molecular form. An active line of contemporary research is dedicated to the adsorption and storage of hydrogen on metal-doped carbon materials. Using density functional theory and van der Waals corrections we have studied molecular and dissociative adsorption of H2 on neutral and cationic C60Con complexes with n = 1–8. The Co atoms form compact clusters on the surface of the fullerene. Dissociative chemisorption of one H2 molecule is more stable than molecular adsorption on neutral C60Con, with the only exception of C60Co. When C60Con is ionized, the electronic charge deficit remains localized in the cobalt cluster. The molecular and dissociative adsorption features on cationic C60Con+ and neutral C60Con complexes are in general similar, but some differences can be highlighted. Molecular and dissociative H2 adsorption on C60Co2+ are competitive; in fact, molecular adsorption is slightly more stable as a result of the localized electronic charge deficit on the Co dimer. Another difference is that the dissociative adsorption energies on some of the neutral C60Con complexes are substantially larger than the dissociative adsorption energies on the corresponding C60Con+ cationic complexes by amounts between 0.2 and 0.5 eV. Activation barriers for dissociation of the adsorbed H2 molecule strongly depend on the charge state and cluster size. These barriers help to interpret the adsorption state (molecular or dissociated) of experimentally produced hydrogenated C60Con+ complexes. Hydrogen saturation has been studied in two cases. C60Co adsorbs three H2 units in molecular form, and C60Con adsorbs up to thirteen H2 units, four dissociated and nine in molecular form. ispartof: International Journal of Hydrogen Energy vol:46 issue:39 pages:20594-20606 status: published
- Published
- 2021
36. Particulate matter in aerosols produced by two last generation electronic cigarettes: a comparison in a real-world environment
- Author
-
Alessandro Borgini, Ario Ruprecht, Ruaraidh Dobson, Sean Semple, Alessandra Lugo, Á López Nicolás, Olena Tigova, Chiara Veronese, Esteve Fernández, Andrea Tittarelli, Silvano Gallus, Sheila Keogan, Roberto Boffi, Luke Clancy, C. De Marco, Martina Bertoldi, Anna Tzortzi, María J. López, Xavier Continente, Giulia Carreras, Polina Starchenko, Constantine I. Vardavas, Joan B. Soriano, and Giuseppe Gorini
- Subjects
Pulmonary and Respiratory Medicine ,03 medical and health sciences ,0302 clinical medicine ,030228 respiratory system ,Particle number ,business.industry ,Medicine ,030212 general & internal medicine ,Particulates ,Atmospheric sciences ,business - Abstract
The design of e-cigarettes (e-cigs) is constantly evolving and the latest models can aerosolize using high-power sub-ohm resistance and hence may produce specific particle concentrations. The aim of this study was to evaluate the aerosol characteristics generated by two different types of electronic cigarette in real-world conditions, such as a sitting room or a small office, in number of particles (particles/cm
- Published
- 2021
- Full Text
- View/download PDF
37. Interaction of hydrogen with palladium–copper nanoalloys
- Author
-
Estefania German, Alfonso Gómez Herranz, María J. López, and Julio A. Alonso
- Subjects
Materials science ,010304 chemical physics ,Hydrogen ,Alloy ,chemistry.chemical_element ,engineering.material ,010402 general chemistry ,01 natural sciences ,Copper ,0104 chemical sciences ,Nanoclusters ,Metal ,Hydrogen storage ,Adsorption ,Chemical engineering ,chemistry ,visual_art ,0103 physical sciences ,visual_art.visual_art_medium ,engineering ,Physical and Theoretical Chemistry ,Palladium - Abstract
Doping porous carbons with palladium nanoparticles is known to enhance the hydrogen storage capacity of these materials. Alloying palladium with the non-expensive metal copper will reduce the cost of the nanoparticles. We have studied how alloying with copper affects the hydrogen adsorption properties of CumPdn clusters with m + n = 6. Formation of CumPdn nanoalloys is favorable, a fact consistent with the formation of bulk solid Cu–Pd alloys. Molecular adsorption of H2 and dissociative chemisorption are both exothermic, and dissociative chemisorption is energetically favorable compared to molecular adsorption. The geometric structures of the CumPdn clusters are maintained, in general, after molecular or dissociative adsorption of H2, with very few exceptions. Adsorption binding energies on some alloy nanoclusters rich in Cu are higher than adsorption binding energies on Pd6, so alloying with Cu may become a way to improve hydrogen adsorption in Pd-doped porous carbon materials.
- Published
- 2021
- Full Text
- View/download PDF
38. Mechanical complications of acute myocardial infarction in the COVID era
- Author
-
Carolina, Barajas-Díaz, Enrique, Pérez-de la Sota, María J, López-Gude, Andrea, Eixerés-Esteve, and José, Cortina-Romero
- Subjects
SARS-CoV-2 ,Myocardial Infarction ,COVID-19 ,Humans ,ST Elevation Myocardial Infarction - Published
- 2021
39. Impact of Preoperative Total Proteins and Glycated Hemoglobin on Recurrences after Early Colorectal Cancer
- Author
-
Alberto López, Ana Zaida Gómez Moreno, María-José Cao, María J. López, María-José Castro, Jose María Jiménez, Jaime Ruiz-Tovar, and Jair Santos-Torres
- Subjects
Blood Glucose ,Male ,Cancer Research ,Colorectal cancer ,Gastroenterology ,chemistry.chemical_compound ,Postoperative Complications ,0302 clinical medicine ,Risk Factors ,Rectum - Surgery ,Prospective Studies ,030212 general & internal medicine ,Stage (cooking) ,Colectomy ,Hypoproteinemia ,Proctectomy ,Nutrition and Dietetics ,total proteins ,Blood Proteins ,Middle Aged ,Lipids ,3201.01 Oncología ,Treatment Outcome ,Oncology ,030220 oncology & carcinogenesis ,Surgical oncology ,Preoperative Period ,outcome ,Female ,Colorectal Neoplasms ,lcsh:Nutrition. Foods and food supply ,medicine.medical_specialty ,Outcome assessment (Medical care) ,Nutritional Status ,lcsh:TX341-641 ,Article ,03 medical and health sciences ,Predictive Value of Tests ,Càncer colorectal ,32 Ciencias Médicas ,Internal medicine ,medicine ,Humans ,Elective surgery ,Aged ,Neoplasm Staging ,Glycemic ,Nutrition ,Recto - Cáncer ,business.industry ,Albumin ,Proteins ,medicine.disease ,Colon - Cáncer ,Proteínas ,Glycosylated hemoglobin - Measurement ,early colorectal cancer ,Nutrition Assessment ,chemistry ,Observational study ,Glycated hemoglobin ,Neoplasm Recurrence, Local ,business ,Colorectal Surgery ,Food Science ,glycated hemoglobin - Abstract
Background: The outcome of colorectal cancer is mostly based on TNM classification. There are several factors determining that patients with the same tumoral stage present different outcomes. The nutritional status has been related to the immunological response and may affect the oncologic results. The purpose of this study was to determine if preoperative nutritional parameters may predict the oncologic outcome in patients with early colorectal cancer. Methods: A prospective observational study of patients undergoing elective surgery for colorectal cancer was performed with stage I. Preoperative nutritional assessment included glycemic and lipid profiles, total proteins, and albumin levels. These parameters were correlated with tumoral recurrence during a follow-up of at least 24 months. Results: During the period of study, 744 patients were operated on and 228 (30.6%) followed the inclusion criteria for this study. Recurrence rate was 5.7% (13 patients). Patients with hypoproteinemia showed a 7.8-fold greater risk of recurrence during the first 24 months after surgery [OR 7.8 (CI95% 1.3-48), p = 0.012]. Patients with glycated hemoglobin levels (HbA1c) >, 6.2% showed a 2.3 increased risk of recurrence [OR 2.3 (CI95% 1.1-4.7, p = 0.01]. Conclusions: Preoperative values of total proteins and HbA1c correlate with the recurrence rate in early colorectal cancer.
- Published
- 2021
- Full Text
- View/download PDF
40. Los productos de tabaco calentado: nuevo reto en el control del tabaco
- Author
-
Esteve Fernández, Isabel Nerín, Armando Peruga, Xisca Sureda, Rodrigo Córdoba García, Francisco Rodríguez Lozano, and María J. López
- Subjects
Modified risk ,Tobacco industry ,Food and drug administration ,Reduced exposure ,03 medical and health sciences ,0302 clinical medicine ,Hàbit de fumar ,Tobacco ,media_common.cataloged_instance ,030212 general & internal medicine ,European union ,health care economics and organizations ,Industria tabaquera ,media_common ,IQOS ,Daños de salud ,030503 health policy & services ,Smoking ,technology, industry, and agriculture ,Public Health, Environmental and Occupational Health ,Advertising ,Health damage ,Riesgo modificado ,Tabaco ,Indústria tabaquera ,Exposición reducida ,Business ,Public aspects of medicine ,RA1-1270 ,0305 other medical science ,Tobacco product - Abstract
Resumen: Con las ventas de cigarrillos disminuyendo, la industria del tabaco se ha encomendado a la venta de los productos de tabaco calentado (PTC), cuyas ventas están aumentando. Hemos visto con preocupación informaciones que indican erróneamente que el tabaco calentado se asocia a un menor riesgo de cáncer y otras enfermedades que los cigarrillos convencionales, citando a la Food and Drug Administration (FDA) de los Estados Unidos como fuente. Es cierto que la FDA ha autorizado la venta de un PTC, pero niega que esta aprobación suponga un apoyo al producto o indique que este sea inocuo. Philip Morris pidió a la FDA que su PTC fuera aprobado como un producto de tabaco de «riesgo modificado», pero la Agencia negó que el riesgo para la salud de las personas usuarias fuese menor que el de los cigarrillos convencionales, a pesar de emitir menos cantidad de algunos tóxicos. España y la Unión Europea deberían acabar con los privilegios regulatorios de los que disfrutan los PTC. Identificamos por lo menos cinco aspectos que deben mejorarse: 1) el cumplimiento de la prohibición de su uso donde está prohibido fumar; 2) el control de la prohibición de publicidad, promoción y patrocinio de los PTC; 3) que los PTC lleven el mismo tipo de etiquetado que los cigarrillos; 4) limitar que los PTC tengan aromas característicos; y 5) tratar los PTC fiscalmente igual que los cigarrillos. Abstract: As cigarette sales decline, the tobacco industry has turned to the sale of heated tobacco products (HTP), which are on the rise. We are concerned with reports erroneously indicating that heated tobacco is associated with a lower risk of cancer and other diseases than conventional cigarettes, citing as a source the Food and Drug Administration (FDA) of the United States. The FDA has indeed authorized the sale of an HTP, but denies that this approval is an endorsement of the product or that it is safe. Philip Morris asked the FDA to approve this product as a “modified risk” tobacco product. However, the Agency denied that the risk to users’ health was less than conventional cigarettes, despite emitting less amount of some toxicants. Spain and the European Union should end the regulatory privileges that HTPs have until now. We identified at least five aspects to improve: 1) compliance with the prohibition of HTPs use where smoking is prohibited; 2) control of the prohibition of advertising, promotion, and sponsorship of HTPs; 3) that HTPs carry the same type of labeling as cigarettes; 4) limit that HTPs have characteristic aromas; and 5) treat HTPs fiscally at the same level as cigarettes.
- Published
- 2021
41. Secrecy and Community in 21st-Century Fiction
- Author
-
Pilar Villar-Argáiz and María J. López
- Subjects
History ,Law ,Secrecy - Published
- 2021
- Full Text
- View/download PDF
42. Application of sonicated extracts of cyanobacteria and microalgae for the mitigation of bacterial canker in tomato seedlings
- Author
-
J.A. López-González, María J. López, M.M. Jurado, Maria R. Martínez-Gallardo, Francisca Suárez-Estrella, and A.J. Toribio
- Subjects
0106 biological sciences ,2. Zero hunger ,Cyanobacteria ,0303 health sciences ,Nostoc ,biology ,Plant physiology ,Plant Science ,Aquatic Science ,biology.organism_classification ,01 natural sciences ,03 medical and health sciences ,Horticulture ,chemistry.chemical_compound ,chemistry ,Germination ,Bioassay ,Clavibacter michiganensis ,Scenedesmus ,Salicylic acid ,030304 developmental biology ,010606 plant biology & botany - Abstract
Microalgae and cyanobacteria could play an important role in crop protection, since they produce bioactive substances that promote plant growth and/or trigger the plant resistance mechanisms. The present study focuses on the control of bacterial canker caused byClavibacter michiganensissubsp.michiganensison tomato plants by using sonicated extracts from cyanobacteria and microalgae of the generaLeptolyngbya,Nostoc,Chlorella, andScenedesmus. For the development of this study, 8 strains were firstly tested for their capacity to inhibit the growth ofC. michiganensissubsp.michiganensisin vitro, as well as to produce cytokinins and salicylic acid. In order to discard those more phytotoxic strains, the germination index was also estimated in watercress seeds.Scenedesmus-677 andLeptolyngbya-1267 strains were selected in this first phase based on their pesticide and phytostimulant capacity in vitro. Subsequent bioassays on tomato seedlings showed that root application ofScenedesmus-677 could be more aimed at controlling the disease caused byC. michiganensissubsp.michiganensis, while foliar and root application ofLeptolyngbya-1267 seems to be more related to the strengthening of the plant through the salicylic acid route. These preliminary results could serve as the basis for a deeper characterization of the biopesticidal and biostimulant effect of both strains, as well as to reveal the benefits derived from the combination of both capacities.
- Published
- 2021
- Full Text
- View/download PDF
43. Energy poverty, its intensity and health in vulnerable populations in a Southern European city
- Author
-
Laura Oliveras, María J. López, Ana M. Novoa, Joan Benach, Juli Carrere, Andrés Peralta, and Marc Marí-Dell’Olmo
- Subjects
Male ,Desigualdades sociales en salud ,Sociodemographic Factors ,Vulnerable populations ,Salud ,Determinantes sociales de la salud ,03 medical and health sciences ,Social determinants of health ,0302 clinical medicine ,Political science ,Humans ,030212 general & internal medicine ,Poverty ,Energy poverty ,030505 public health ,Health Vulnerable populations ,Public Health, Environmental and Occupational Health ,Social health inequalities ,Pobreza energética ,Cross-Sectional Studies ,Fuel poverty ,Spain ,Health ,Población vulnerable ,Female ,Public aspects of medicine ,RA1-1270 ,0305 other medical science ,Humanities - Abstract
Objective: To describe and compare the health status between vulnerable population participating in a program to tackle energy poverty (Energía, la justa) and the non-energy poor Barcelona (Spain) population and to analyse among participants the effect of energy poverty intensity on health. Method: Cross-sectional study based on data from program participants obtained before the intervention. Participants (1799 women and 671 men) were compared to non-energy poor population of Barcelona (1393 women and 1215 men) sampled from the Barcelona Public Health Survey (2016). Standardized prevalence and prevalence ratios of self-perceived poor health, asthma, chronic bronchitis, and depression and/or anxiety were estimated, and among participants the association between health status and energy poverty intensity was estimated with multivariate models. Results: The probability of poor self-perceived physical and mental health ranged from 2.2 to 5.3 times greater in the program participants than non-energy poor Barcelona population. Among program participants, those most affected were found to be the most likely to report poor health outcomes, regardless of other sociodemographic factors. Conclusions: The prevalence of poor physical and mental health was considerably higher among women and men participating in the programme compared to the non-energy poor population and was even worse among those who were more severely affected. Public policies that tackle energy poverty and its consequences are urgently needed in Spain. Resumen: Objetivo: Describir y comparar el estado de salud entre la población vulnerable que participa en un programa de lucha contra la pobreza energética (Energía, la justa) y la población sin pobreza energética de Barcelona (España), y analizar entre las personas participantes el efecto de la intensidad de la pobreza energética en la salud. Método: Estudio transversal basado en datos de los/las participantes en el programa obtenidos antes de la intervención. Se compararon los/las participantes (1799 mujeres y 671 hombres) con población sin pobreza energética de Barcelona (1393 mujeres y 1215 hombres) seleccionada de la Encuesta de Salud Pública de Barcelona (2016). Se estimaron la prevalencia estandarizada y las razones de prevalencia de mala salud, asma, bronquitis crónica y depresión o ansiedad autopercibida. Entre los/las participantes se estimó la asociación entre el estado de salud y la intensidad de la pobreza energética con modelos multivariantes. Resultados: Los/las participantes presentaron entre 2,2 y 5,3 veces peores resultados en salud que la población sin pobreza energética. Entre los/las participantes se encontró que las personas más afectadas eran las que tenían más probabilidades de reportar peores resultados de salud, independientemente de otros factores sociodemográficos. Conclusiones: La prevalencia de mala salud física y mental era considerablemente mayor en las mujeres y los hombres que participaron en el programa en comparación con la población sin pobreza energética, y era aún peor entre los/las más severamente afectados. En España se necesitan con urgencia políticas públicas que aborden la pobreza energética y sus consecuencias.
- Published
- 2021
44. Assessment of risk factors associated with cardiovascular diseases in overweight women
- Author
-
Irene Albertos, Jaime Ruiz-Tovar, María-José Castro, Jose María Jiménez, María-José Cao, Manuel Duran, Sara García, and María J. López
- Subjects
Adult ,medicine.medical_specialty ,Waist ,Riesgo cardiovascular ,Cardiovascular risk factors ,Obesidad ,Overweight ,Índice de masa corporal ,Article ,Risk Factors ,Internal medicine ,Electric Impedance ,Medicine ,Humans ,TX341-641 ,Breast ,Cardiovascular, aparato Enfermedades ,Body mass index ,Nutrition and Dietetics ,Framingham Risk Score ,Nutrition. Foods and food supply ,business.industry ,Waist-Hip Ratio ,Organ Size ,Anthropometry ,medicine.disease ,Cardiovascular risk ,Obesity ,3207.04 Patología Cardiovascular ,Mammary volume ,Volumen mamario ,Cardiovascular Diseases ,Sobrepeso ,Observational study ,Female ,women ,Menopausia ,medicine.symptom ,business ,Food Science - Abstract
Producción Científica, The assessment of anthropometric variables has been shown to be useful as a predictor of cardiovascular risk in overweight and obese patients. The aim of this study was to determine the usefulness of the relationship between breast volume and body mass index as an indicator of cardiovascular risk in premenopausal women with overweight and mild obesity. A prospective observational study of 93 premenopausal women was performed. Evaluation of anthropometric measures included age, body mass index, waist and hip circumferences, breast projection, and ptosis. Cardiovascular risk factors were evaluated using the Framingham cardiovascular risk score, the triglycerides/HDL cholesterol ratio and the waist-hip ratio. Ninety-three women were included, with a mean 36.4 ± 7.5 years. Mean BMI was 27.3 ± 1.9 kg/m2, waist-to-Hip ratio was 0.8 ± 0.07, and mammary volume was 1045 ± 657.4 cm3. Mean body fat mass was 30.6 + 3.6% and mean visceral fat was 6.6 + 3.2%. The mean triglycerides to HDL ratio was 1.7 ± 0.8 and waist-to-hip ratio was 0.8 ± 0.07. Breast volume related to body mass index can be used as a predictor of cardiovascular risk in premenopausal women who are overweight and mildly obese.
- Published
- 2021
- Full Text
- View/download PDF
45. Analysis of burnout syndrome and resilience in nurses throughout the COVID-19 pandemic: A cross-sectional study
- Author
-
María-José Castro, Sofía Luis-Vian, Jose María Jiménez, María J. López, Noel Rivas, Verónica Velasco-González, Sara García, Mercedes Fernández-Castro, and María-José Cao
- Subjects
2019-20 coronavirus outbreak ,Nursing staff ,Coronavirus disease 2019 (COVID-19) ,Cross-sectional study ,Health, Toxicology and Mutagenesis ,media_common.quotation_subject ,Burnout syndrome ,Nurses ,Burnout ,professional ,Article ,Agotamiento ,COVID-19 (Disease) ,Surveys and Questionnaires ,Pandemic ,Humans ,Medicine ,Burnout, Professional ,Pandemics ,resilience ,6306.04 Sociología Médica ,media_common ,Enfermeras ,SARS-CoV-2 ,business.industry ,Public Health, Environmental and Occupational Health ,COVID-19 ,Resilience, Psychological ,Cross-Sectional Studies ,Resiliencia ,Psychological ,Psychological resilience ,business ,61 Psicología ,Enfermedades profesionales ,Clinical psychology ,Psicológico - Abstract
Background: The COVID-19 pandemic has contributed to the occurrence of work-related stress on nursing staff. Being resilience an essential element to countering adversity. The aim of the study was to assess burnout syndrome as well as resilience in hospital-care nurses during the first outbreak of the COVID-19 pandemic. Methods: A cross-sectional descriptive study of burnout syndrome and resilience of 101 nurses during the first COVID-19 outbreak. The Maslach Burnout Inventory and the Scale of Resilience of Connor-Davidson were used. Results: The burnout average score was 74.35 ± 12.78 points, and resilience was 27.94 ± 5.84. Temporary nurses reached a lower average score for the emotional fatigue dimension (23.80 ± 10.39 points) p <, 0.05. The emotional fatigue dimension correlated adversely with the average score of resilience (r = −0.271, p <, 0.001). Conclusions: The level of burnout in nurses was high, being higher on those who took care of COVID-19 patients. Resilient nurses were able to better cope with stressful situations.
- Published
- 2021
- Full Text
- View/download PDF
46. African strangers, spaces of belonging and the 'democracy to come' in Helon Habila’s Travellers
- Author
-
María J. López
- Subjects
Literature and Literary Theory - Abstract
This article analyses Helon Habila’s Travellers (2019), focusing on its depiction of African migrants in Europe as strangers, as defined by Sara Ahmed in Strange Encounters (2000): those who, in spite of their proximity, are recognized as not belonging or out of place. Following Ahmed, this essay deals with the relation between space and migrant experience in Habila’s novel, in which the configuration of cities such as Berlin and London and of Europe as a whole is presented as characterized by the enforcement of boundaries and spaces of belonging (Ahmed, 2000), so that the African stranger emerges as an undesirable, threatening, foreign element to be feared and expelled. On the other hand, such a logic of defensiveness, homogeneity, and exclusion is partly challenged and undermined in Travellers by acts of resistance carried out by both African and European characters and by acts of domestic hospitality. These acts suggest the disruption of frontiers and borders, and their corresponding sealed and homogeneous spaces (Ahmed, 2000), together with the necessity of exercising hospitality at a collective and political level. As opposed to the configuration of Europe as Fortress Europe, in which identity and community are defined in terms of affiliation to roots, homeland, or race, in Travellers we find thus an appeal to what Jacques Derrida has called the “democracy to come”, a political, always deferred space of unconditional hospitality that opens up to the foreigner and the stranger.
- Published
- 2022
- Full Text
- View/download PDF
47. Mortalidad atribuida al tabaquismo en España: ¿Quo vadis?
- Author
-
Esteve Fernández, Mónica Pérez-Ríos, and María J. López
- Subjects
Pulmonary and Respiratory Medicine ,business.industry ,Medicine ,business ,Humanities - Published
- 2021
- Full Text
- View/download PDF
48. Revisiting the succession of microbial populations throughout composting: A matter of thermotolerance
- Author
-
J.A. López-González, María J. Estrella-González, Francisca Suárez-Estrella, Joaquín Moreno, María J. López, M.A. Arcos-Nievas, and M.M. Jurado
- Subjects
Thermotolerance ,Environmental Engineering ,010504 meteorology & atmospheric sciences ,Firmicutes ,010501 environmental sciences ,01 natural sciences ,Actinobacteria ,Soil ,Environmental Chemistry ,Waste Management and Disposal ,Soil Microbiology ,0105 earth and related environmental sciences ,biology ,Strain (chemistry) ,Ascomycota ,Bacteria ,Thermophile ,Basidiomycota ,Composting ,Microbiota ,biology.organism_classification ,Pollution ,Manure ,Horticulture ,Proteobacteria ,Mesophile - Abstract
Composting has been traditionally considered a process in which a succession of mesophilic and thermophilic microbial populations occurs due to temperature changes. In order to deepen in this model, 1380 bacterial and fungal strains (the entire culturable microbiota isolated from a composting process) were investigated for their ability to grow across a wide range of temperatures (20 to 60 °C). First, qualitative tests were performed to establish a thermal profile for each strain. Then, quantitative tests allowed ascertaining the extent of growth for each strain at each of the tested temperatures. The identity of the isolates enabled to position them taxonomically and permitted tracking the strains throughout the process. Results showed that 90% of the isolates were classified as thermotolerant (they grew at all tested temperatures). Only 9% and 1% of the studied strains showed to be strictly mesophilic or thermophilic, respectively. Firmicutes exhibited the greatest thermal plasticity, followed by Actinobacteria and Ascomycota. Most of the Proteobacteria and all Basidiomycota strains were also able to grow at all the assayed temperatures. Thermotolerance was clearly demonstrated among the composting microbiota, suggesting that the idea of the succession of mesophilic and thermophilic populations throughout the process might need a reassessment.
- Published
- 2020
49. Assessment of body composition in obese patients undergoing one anastomosis gastric bypass: cross-sectional study
- Author
-
Jaime Ruiz-Tovar, Artur Marc-Hernández, María J. López, María-José Castro, Jose María Jiménez, Sara García, Miguel-Angel Carbajo, and María-José Cao
- Subjects
Adult ,Male ,medicine.medical_specialty ,Cross-sectional study ,Gastric bypass ,Gastric Bypass ,lcsh:Medicine ,030209 endocrinology & metabolism ,Anastomosis ,Article ,Body Mass Index ,03 medical and health sciences ,Endocrinology ,0302 clinical medicine ,Weight loss ,medicine ,Humans ,In patient ,Obesity ,Postoperative Period ,030212 general & internal medicine ,lcsh:Science ,Multidisciplinary ,business.industry ,lcsh:R ,Health care ,Middle Aged ,medicine.disease ,Surgery ,Cross-Sectional Studies ,Treatment Outcome ,Body Composition ,Female ,lcsh:Q ,Observational study ,medicine.symptom ,business ,Body mass index - Abstract
Bariatric surgery is the most effective long-term treatment to obesity, and it is necessary to assess changes in body composition and to be able to establish better follow-up of patients. Cross-sectional, observational study in patients undergoing One Anastomosis Gastric Bypass (OAGB) bariatric surgery. We analysed changes in weight and body composition during the first postoperative year. 405 patients (68.9% women. 31.1% men), mean age 44 years, mean weight 110.02 kg, Body Mass Index (BMI) 39.76 kg/m2, height 1.66 m. The variables analyzed were substantially decreased compared to the preoperative values one year after surgery in every case: weight (110.02 ± 22.03 kg vs. 69.36 ± 13.60 kg), BMI (39.76 ± 6.65 vs. 24.52 ± 3. 76), fat free mass (61.12 ± 12.43 kg vs. 53.61 ± 11.61 kg), fat mass (50.44 ± 14.36 kg vs. 15.74 ± 6.74 kg), bone mass (58.06 ± 11.85 kg vs. 50.92 ± 11.06 kg) and water (45.08 ± 9.99 kg vs. 37.39 ± 9.23 kg), P < 0.001. The results show noticeable improvements in weight reduction and changes in body composition, and will contribute to develop a thorough understanding of both of them, contributing also to perform a better patients’ follow-up.
- Published
- 2020
- Full Text
- View/download PDF
50. Dietary tryptophan depletion alters the faecal bacterial community structure of compulsive drinker rats in schedule-induced polydipsia
- Author
-
Margarita Moreno, María J. López, Joaquín Moreno, Pilar Flores, Fernando Sánchez-Santed, Ana Merchán, and Cristian Pérez-Fernández
- Subjects
medicine.medical_specialty ,Experimental and Cognitive Psychology ,Biology ,Gut flora ,Serotonergic ,03 medical and health sciences ,Behavioral Neuroscience ,0302 clinical medicine ,Neurotrophic factors ,Internal medicine ,RNA, Ribosomal, 16S ,medicine ,Animals ,0501 psychology and cognitive sciences ,Polydipsia ,050102 behavioral science & comparative psychology ,Rats, Wistar ,Brain-derived neurotrophic factor ,05 social sciences ,Tryptophan ,biology.organism_classification ,medicine.disease ,Diet ,Rats ,Endocrinology ,Schizophrenia ,Serotonin ,medicine.symptom ,Licking ,030217 neurology & neurosurgery - Abstract
Rationale Compulsive behaviour, present in different psychiatric disorders such as obsessive-compulsive disorder, schizophrenia and drug abuse, is associated with altered levels of serotonin (5-hydroxytryptamine, 5-HT). The gut microbiota regulates tryptophan (TRP) metabolism and may affect global 5-H synthesis in the enteric and central nervous systems, suggesting a possible involvement of gut microbiota in compulsive spectrum disorders. Objectives The present study investigated whether chronic TRP depletion by diet alters the faecal bacterial community profiles of compulsive versus non-compulsive rats in schedule-induced polydipsia (SIP). Peripheral plasma 5-HT and brain-derived neurotrophic factor (BDNF) levels were evaluated. Methods Wistar rats were selected as High Drinkers (HD) or Low Drinkers (LD) according to their SIP behaviour and were fed for 14 days with either a TRP-free diet (T-) or a TRP-supplemented diet (T+). The faecal bacterial community structure was investigated with 16S rRNA gene-targeted denaturing gradient gel electrophoresis (DGGE) fingerprinting analysis. Results Compulsive HD rats showed a lower bacterial diversity than LD rats, irrespectively of the diet. The TRP-depleted HD rats, the only group increasing compulsive licking in SIP, showed a reduction of bacterial evenness and a highly functionally organized community compared with the other groups, indicating that this bacterial community is more fragile to external changes due to the dominance of a low number of species. The chronic TRP depletion by diet effectively reduced peripheral plasma 5-HT levels in both HD and LD rats, while plasma BDNF levels were not altered. Conclusions These results highlight the possible implication of reduced microbial diversity in compulsive behaviour and the involvement of the serotonergic system in modulating the gut brain-axis in compulsive spectrum disorders.
- Published
- 2020
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.