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994 results on '"M. Yamauchi"'

1. First-In-Human Pilot PET Immunoimaging Study of 64Cu-Anti-Carcinoembryonic Antigen Monoclonal Antibody (hT84.66-M5A) in Patients with Carcinoembryonic Antigen-Producing Cancers

Author

Jeffrey Y.C. Wong, David M. Yamauchi, Vikram Adhikarla, Jennifer Simpson, Paul H. Frankel, Yuman Fong, Kurt A. Melstrom, Yi-jen Chen, Behrooz D. Salehian, Yanghee Woo, Savita V. Dandapani, David M. Colcher, Erasmus K. Poku, Paul J. Yazaki, Anna M. Wu, and John E. Shively

Subjects
Pharmacology, Cancer Research, Oncology, Radiology, Nuclear Medicine and imaging, General Medicine
Published
2023

3. Bifunctional electrochemical properties of La0.8Sr0.2Co0.8M0.2O3−δ(M = Ni, Fe, Mn, and Cu): efficient elemental doping based on a structural and pH-dependent study

Author

Junfang Cheng, N. Maeda, B. Chi, Naotoshi Nakashima, P. Ganesan, M. Yamauchi, Junko Matsuda, M. Zhang, G. Zhang, and Z. Wang

Subjects
Materials science, Inorganic chemistry, Doping, Oxygen evolution, Oxide, Carbon nanotube, Electrochemistry, Catalysis, law.invention, chemistry.chemical_compound, chemistry, Chemistry (miscellaneous), law, General Materials Science, Bifunctional, Perovskite (structure)
Abstract

Perovskite oxides with a low cost and high catalytic activity are considered as suitable candidates for the oxygen evolution reaction (OER)/oxygen reduction reaction (ORR), but most of them favour only either the ORR or the OER. Besides, their underlying catalytic mechanisms are subject of an ongoing debate. Herein, La0.8Sr0.2CoO3−δ (LSC) was selected as a base perovskite oxide for doping different elements into its B-site to fabricate four different La0.8Sr0.2Co0.8M0.2O3−δ (LSCM; M = Ni, Fe, Mn, and Cu) perovskite oxides. Among the catalysts tested with and without multi-walled carbon nanotubes (MWNTs), La0.8Sr0.2Co0.8Fe0.2O3−δ (LSCF) outperformed any other catalysts in terms of both OER and ORR activity. The OER/ORR activity enhancement with LSCF is also discussed based on spectroscopic and microscopic analyses and lattice oxygen transportation.

Published
2022

4. First-In-Human Pilot PET Immunoimaging Study of

Author

Jeffrey Y C, Wong, David M, Yamauchi, Vikram, Adhikarla, Jennifer, Simpson, Paul H, Frankel, Yuman, Fong, Kurt A, Melstrom, Yi-Jen, Chen, Behrooz D, Salehian, Yanghee, Woo, Savita V, Dandapani, David M, Colcher, Erasmus K, Poku, Paul J, Yazaki, Anna M, Wu, and John E, Shively

Published
2022

5. In Vitro Antimicrobial Screening of Benzoylthioureas: Synthesis, Antibacterial Activity toward Streptococcus agalactiae and Molecular Docking Study

Author

Renata P. Biasi‐Garbin, Marciéli Fabris, Ana Elisa B. Morguette, Gabriella M. Andriani, Weslei R. C. Cabral, Patrícia M. L. Pereira, Tiago O. Brito, Fernando Macedo, Camilo H. Da Silva Lima, César A. C. Lancheros, Celso V. Nakamura, Phileno Pinge‐Filho, Eliandro R. Tavares, Lucy M. Yamauchi, Marcelle L. F. Bispo, and Sueli F. Yamada‐Ogatta

Subjects
General Chemistry
Published
2022

8. The fate of O+ ions observed in the plasma mantle: particle tracing modelling and cluster observations

Author

A. Schillings, H. Gunell, H. Nilsson, A. De Spiegeleer, Y. Ebihara, L. G. Westerberg, M. Yamauchi, and R. Slapak

Subjects
lcsh:Geophysics. Cosmic physics, Physics::Space Physics, lcsh:QC801-809, lcsh:Q, lcsh:Science, lcsh:Physics, lcsh:QC1-999
Abstract

Ion escape is of particular interest for studying the evolution of the atmosphere on geological timescales. Previously, using Cluster-CODIF data, we investigated the oxygen ion outflow from the plasma mantle for different solar wind conditions and geomagnetic activity. We found significant correlations between solar wind parameters, geomagnetic activity (Kp index), and the O+ outflow. From these studies, we suggested that O+ ions observed in the plasma mantle and cusp have enough energy and velocity to escape the magnetosphere and be lost into the solar wind or in the distant magnetotail. Thus, this study aims to investigate where the ions observed in the plasma mantle end up. In order to answer this question, we numerically calculate the trajectories of O+ ions using a tracing code to further test this assumption and determine the fate of the observed ions. Our code consists of a magnetic field model (Tsyganenko T96) and an ionospheric potential model (Weimer 2001) in which particles initiated in the plasma mantle region are launched and traced forward in time. We analysed 131 observations of plasma mantle events in Cluster data between 2001 and 2007, and for each event 200 O+ particles were launched with an initial thermal and parallel bulk velocity corresponding to the velocities observed by Cluster. After the tracing, we found that 98 % of the particles are lost into the solar wind or in the distant tail. Out of these 98 %, 20 % escape via the dayside magnetosphere.

Published
2020

9. DEVELOPMENT OF A JAPANESE INFANT HEAD–CHEST PHANTOM AND INVESTIGATION OF THE CURRENT STATUS OF INFANT HEAD CT EXAMINATIONS IN JAPAN

Author

Mitsuru Ikeda, Keisuke Fujii, Kuniharu Imai, K. Narai, Chiyo Yamauchi-Kawaura, H Shimizu, and M Yamauchi

Subjects
Computed tomography, Radiation Dosage, Imaging phantom, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Japan, medicine, Humans, Radiology, Nuclear Medicine and imaging, Radiation, Radiological and Ultrasound Technology, medicine.diagnostic_test, Phantoms, Imaging, business.industry, Public Health, Environmental and Occupational Health, Infant, Equipment Design, General Medicine, Thorax, 030220 oncology & carcinogenesis, Body Burden, Head (vessel), Thermoluminescent Dosimetry, Tomography, X-Ray Computed, business, Nuclear medicine, Head
Abstract

The aim of this study was to develop a head–chest phantom that could mimic the physique of a Japanese 0.5-year-old child and to investigate the current status of exposure dose in infant head computed tomography examinations in Japan. The phantom was produced by machine processing, and radiophotoluminescence glass dosemeters were installed in the phantom for dose measurement. Organ doses were measured for seven different head scan protocols routinely used in three hospitals. In this study, the average dose of the brain and lens within the scan region was equivalent to that measured using infant phantoms in previous studies. In contrast, the doses of both salivary glands and thyroid glands adjacent to the scan region were 1.4–1.8 times higher than those in previous studies. Expansion of the scan area accompanied by a transition of the scan mode from non-helical to helical may have resulted in the differences in organ doses.

Published
2019

11. Impact of Blood Pressure Visit‐to‐Visit Variability on Adverse Events in Patients With Nonvalvular Atrial Fibrillation: Subanalysis of the J‐RHYTHM Registry

Author

Eitaro Kodani, Hiroshi Inoue, Hirotsugu Atarashi, Ken Okumura, Takeshi Yamashita, Toshiaki Otsuka, Hideki Origasa, H Inoue, K Okumura, H Atarashi, T Yamashita, M Sakurai, Y Kawamura, I Kubota, Y Kaneko, K Matsumoto, S Ogawa, Y Aizawa, I Kodama, E Watanabe, Y Koretsune, Y Okuyama, A Shimizu, O Igawa, S Bando, M Fukatani, T Saikawa, A Chishaki, H Origasa, N Kato, K. Kanda, J Kato, H Obata, M Aoki, H. Honda, Y Konta, T Hatayama, Y Abe, K Terata, T Yagi, A Ishida, T Komatsu, H Tachibana, H Suzuki, Y Kamiyama, T Watanabe, M Oguma, M Itoh, O Hirono, Y Tsunoda, K Ikeda, T Kanaya, K Sakurai, H Sukekawa, S Nakada, T Itoh, S Tange, M. Manita, M Ohta, H Eguma, R Kato, Y Endo, T Ogino, M Yamazaki, H Kanki, M Uchida, S Miyanaga, K Shibayama, N Toratani, T Kojima, M Ichikawa, M Saito, Y Umeda, T Sawanobori, H Sohara, S Okubo, T Okubo, T. Tokunaga, O Kuboyama, H Ito, Y Kitahara, K Sagara, T Satoh, E Kodani, K Sugi, Y Kobayashi, Y Higashi, T Katoh, Y Hirayama, N Matsumoto, M Takano, T Ikeda, S Yusu, S Niwano, Y Nakazato, Y Kawano, M Sumiyoshi, N Hagiwara, K Murasaki, H Mitamura, S Nakagawa, K Okishige, K Azegami, H Aoyagi, K Sugiyama, M Nishizaki, N Yamawake, I Watanabe, K Ohkubo, H Sakurada, S Fukamizu, M Suzuki, W Nagahori, T Nakamura, Y Murakawa, N Hayami, K Yoshioka, M Amino, K Hirao, A Yagishita, K Ajiki, K Fujiu, Y Imai, A Yamashina, T Ishiyama, M Sakabe, K Nishida, H Asanoi, H Ueno, null Lee, Y Mitsuke, H Furushima, K Ebe, M Tagawa, M Sato, M. Morikawa, K Yamashiro, K Takami, T Ozawa, M Watarai, M Yamauchi, H Kamiya, H. Hirayama, Y. Yoshida, T Murohara, Y Inden, H Osanai, N Ohte, T Goto, I Morishima, T Yamamoto, E Fujii, M Senga, H. Hayashi, T Urushida, Y Takada, N Tsuboi, T Noda, T Hirose, T Onodera, S Kageyama, T Osaka, T. Tomita, K Shimada, M Nomura, H Izawa, A Sugiura, T Arakawa, K. Kimura, T Mine, T Makita, H Mizuno, A Kobori, T Haruna, M Takagi, N Tanaka, H Shimizu, T Kurita, K Motoki, N Takeda, Y Kijima, M Ito, A Nakata, Y Ueda, A Hirata, S Kamakura, K Satomi, Y. Yamada, Y. Yoshiga, H Ogawa, M Kimura, T Hayano, T Kinbara, H Tatsuno, M Harada, K. Kusano, M Adachi, A Yano, M Sawaguchi, J Yamasaki, T Matsuura, Y Tanaka, H Moritani, T Maki, S Okada, M Takechi, T Hamada, A Nishikado, Y Takagi, I Matsumoto, T Soeki, Y Doi, M Okawa, H Seo, S Kitamura, K Yamamoto, M Akizawa, N Kaname, S Ando, S Narita, T Inou, Y Fukuizumi, K Saku, M Ogawa, Y Urabe, M Ikeuchi, S Harada, H Yamabe, Y Imamura, Y. Yamanouchi, K Sadamatsu, K Yoshida, T Kubota, N Takahashi, N Makino, Y Higuchi, T Ooie, T Iwao, K. Kitamura, T Imamura, K Maemura, N Komiya, M Hayano, H Yoshida, and K. Kumagai

Subjects
Male, medicine.medical_specialty, Hemorrhage, Risk Assessment, Rhythm, Japan, Risk Factors, Cause of Death, Thromboembolism, Internal medicine, Atrial Fibrillation, Ambulatory Care, medicine, Humans, Arrhythmia and Electrophysiology, In patient, Registries, Risk factor, Adverse effect, Original Research, Aged, Analysis of Variance, variability, Clinical events, business.industry, blood pressure, Anticoagulants, Blood Pressure Determination, Atrial fibrillation, medicine.disease, Blood pressure, major hemorrhage, Hypertension, Cardiology, Female, Warfarin, Cardiology and Cardiovascular Medicine, business, Platelet Aggregation Inhibitors
Abstract

Background Blood pressure (BP) variability has reportedly been a risk factor for various clinical events. To clarify the influence of BP visit‐to‐visit variability on adverse events in patients with nonvalvular atrial fibrillation, a post hoc analysis of the J‐RHYTHM Registry was performed. Methods and Results Of 7406 outpatients with nonvalvular atrial fibrillation from 158 institutions, 7226 (age, 69.7±9.9 years; men, 70.7%), in whom BP was measured 4 times or more (14.6±5.0 times) during the 2‐year follow‐up period or until occurrence of an event, constituted the study group. SD and coefficient of variation of BP values were calculated as BP variability. Thromboembolism, major hemorrhage, and all‐cause death occurred in 110 (1.5%), 121 (1.7%), and 168 (2.3%) patients, respectively. When patients were divided into quartiles of systolic BP‐SD (P =0.015 for thromboembolism; HR, 2.60, 95% CI, 1.36–4.97, P =0.004 for major hemorrhage; and HR, 1.85, 95% CI, 1.11–3.07, P =0.018 for all‐cause death) after adjusting for components of the CHA 2 DS 2 ‐VASc score, warfarin and antiplatelet use, atrial fibrillation type, BP measurement times, and others. These findings were consistent when BP‐coefficient of variation was used instead of BP‐SD. Conclusions Systolic BP visit‐to‐visit variability was significantly associated with all adverse events in patients with nonvalvular atrial fibrillation. Further studies are needed to clarify the causality between BP variability and adverse outcomes in patients with nonvalvular atrial fibrillation. Registration URL: https://www.umin.ac.jp/ctr/ ; Unique Identifier: UMIN000001569.

Published
2021

12. Terrestrial ion escape and relevant circulation in space

Author

M. Yamauchi

Subjects
Atmospheric Science, 010504 meteorology & atmospheric sciences, Magnetosphere, Plasmasphere, 01 natural sciences, Magnetosheath, Physics::Plasma Physics, 0103 physical sciences, Earth and Planetary Sciences (miscellaneous), lcsh:Science, 010303 astronomy & astrophysics, 0105 earth and related environmental sciences, Physics, lcsh:QC801-809, Geology, Astronomy and Astrophysics, Escape velocity, lcsh:QC1-999, Computational physics, Solar wind, lcsh:Geophysics. Cosmic physics, Polar wind, Space and Planetary Science, Physics::Space Physics, Magnetopause, lcsh:Q, Ionosphere, lcsh:Physics
Abstract

Observations of the terrestrial ion escape to space and the transport of escaping ions in the magnetosphere are reviewed, with the main stress on subjects that were not covered in reviews over past 2 decades, during which Cluster has significantly improved our knowledge of them. Here, outflowing ions from the ionosphere are classified in terms of energy rather than location: (1) as cold ions refilling the plasmasphere faster than Jeans escape, (2) as cold supersonic ions such as the polar wind, and (3) as suprathermal ions energized by wave–particle interaction or parallel potential acceleration, mainly starting from cold supersonic ions. The majority of the suprathermal ions above the ionosphere become “hot” at high altitudes, with much higher velocity than the escape velocity even for heavy ions. This makes heavy hot ions more abundant in the magnetosphere than heavy ions transported by cold refilling ions or cold supersonic flow. The immediate destination of these terrestrial ions varies from the plasmasphere, the inner magnetosphere including those entering the ionosphere in the other hemisphere and the tailward outer boundaries, the magnetotail, and the solar wind (magnetosheath, cusp, and plasma mantle). Due to time-variable return from the magnetotail, ions with different routes and energy meet in the inner magnetosphere, making it a zoo of different types of ions in both energy and energy distribution. While the mass-independent drift theory has successfully disentangled this zoo of ions, there are many poorly understood phenomena, e.g., mass-dependent energization. Half of the heavy ions in this zoo also finally escape to space, mainly due to magnetopause shadowing (overshooting of ion drift beyond the magnetopause) and charge exchange near the mirror altitude where the exospheric neutral density is at its highest. The amount of heavy ions mixing directly with the solar wind is already the same as or larger than that entering into the magnetotail and is large enough to extract the solar wind kinetic energy in the cusp–plasma mantle through the mass-loading effect and drive the current system near the cusp independently of the global current system. Considering the past solar and solar wind conditions, ion escape might even have influenced the evolution of the terrestrial biosphere.

Published
2019

13. MEASUREMENT OF INTERNAL RADIATION DOSE DISTRIBUTION IN CT EXAMINATIONS USING POLYETHYLENE TEREPHTHALATE RESIN

Author

N Ohzawa, A Fukuyama, N Suga, M Yamauchi, Seiichi Yamamoto, Keisuke Fujii, Nobuhiro Ito, Chiyo Yamauchi-Kawaura, Masataka Komori, and M Kozuka

Subjects
Materials science, Dose distribution, Radiation Dosage, Luminance, Imaging phantom, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Radiation Monitoring, Polyethylene terephthalate, Humans, Dosimetry, Radiology, Nuclear Medicine and imaging, Child, Radiation, Radiological and Ultrasound Technology, Phantoms, Imaging, Polyethylene Terephthalates, Device Camera, Public Health, Environmental and Occupational Health, Internal radiation, General Medicine, equipment and supplies, chemistry, 030220 oncology & carcinogenesis, Tomography, Tomography, X-Ray Computed, Biomedical engineering
Abstract

This study proposes a new dosimetry method for the estimation of the internal radiation dose distribution of a subject undergoing computed tomography (CT) examinations. In this novel method, dose distribution of a subject by CT scans was estimated based on radiophotoluminance distribution with polyethylene terephthalate (PET) resin which was cut to the average head size of a Japanese 1-year-old child. The difference in dose distribution depending on the type of bowtie filter was visualized by imaging luminance distribution with the PET phantom using a charge-coupled device camera. Dose distribution images simulated from a water phantom of the same size as the PET phantom were compared with the luminance distribution images. The linear correlation was demonstrated between luminance of the PET phantom and the simulated water dose. In comparison with the simulated water doses and the converted water doses from luminance of the PET phantom, the relative differences were within 20%.

Published
2018

14. Relative outflow enhancements during major geomagnetic storms – Cluster observations

Author

A. Schillings, H. Nilsson, R. Slapak, M. Yamauchi, and L.-G. Westerberg

Subjects
lcsh:Geophysics. Cosmic physics, lcsh:QC801-809, lcsh:Q, lcsh:Science, lcsh:Physics, lcsh:QC1-999
Abstract

The rate of ion outflow from the polar ionosphere is known to vary by orders of magnitude, depending on the geomagnetic activity. However, the upper limit of the outflow rate during the largest geomagnetic storms is not well constrained due to poor spatial coverage during storm events. In this paper, we analyse six major geomagnetic storms between 2001 and 2004 using Cluster data. The six major storms fulfil the criteria of Dst 7+. Since the shape of the magnetospheric regions (plasma mantle, lobe and inner magnetosphere) are distorted during large magnetic storms, we use both plasma beta (β) and ion characteristics to define a spatial box where the upward O+ flux scaled to an ionospheric reference altitude for the extreme event is observed. The relative enhancement of the scaled outflow in the spatial boxes as compared to the data from the full year when the storm occurred is estimated. Only O+ data were used because H+ may have a solar wind origin. The storm time data for most cases showed up as a clearly distinguishable separate peak in the distribution toward the largest fluxes observed. The relative enhancement in the outflow region during storm time is 1 to 2 orders of magnitude higher compared to less disturbed time. The largest relative scaled outflow enhancement is 83 (7 November 2004) and the highest scaled O+ outflow observed is 2 × 1014 m−2 s−1 (29 October 2003).

Published
2017

15. Quantification of the total ion transport in the near-Earth plasma sheet

Author

R. Slapak, M. Hamrin, T. Pitkänen, M. Yamauchi, H. Nilsson, T. Karlsson, and A. Schillings

Subjects
lcsh:Geophysics. Cosmic physics, TheoryofComputation_ANALYSISOFALGORITHMSANDPROBLEMCOMPLEXITY, lcsh:QC801-809, lcsh:Q, lcsh:Science, lcsh:Physics, lcsh:QC1-999
Abstract

Recent studies strongly suggest that a majority of the observed O+ cusp outflows will eventually escape into the solar wind, rather than be transported to the plasma sheet. Therefore, an investigation of plasma sheet flows will add to these studies and give a more complete picture of magnetospheric ion dynamics. Specifically, it will provide a greater understanding of atmospheric loss. We have used Cluster spacecraft 4 to quantify the H+ and O+ total transports in the near-Earth plasma sheet, using data covering 2001–2005. The results show that both H+ and O+ have earthward net fluxes of the orders of 1026 and 1024 s−1, respectively. The O+ plasma sheet return flux is 1 order of magnitude smaller than the O+ outflows observed in the cusps, strengthening the view that most ionospheric O+ outflows do escape. The H+ return flux is approximately the same as the ionospheric outflow, suggesting a stable budget of H+ in the magnetosphere. However, low-energy H+, not detectable by the ion spectrometer, is not considered in our study, leaving the complete magnetospheric H+ circulation an open question. Studying tailward flows separately reveals a total tailward O+ flux of about 0. 5 × 1025 s−1, which can be considered as a lower limit of the nightside auroral region O+ outflow. Lower velocity flows ( −1) contribute most to the total transports, whereas the high-velocity flows contribute very little, suggesting that bursty bulk flows are not dominant in plasma sheet mass transport.

Published
2017

16. Measurement of the Michel parameters (η‾, ξκ ) in the radiative leptonic decay of τ

Author

J. E. Fast, D. Dossett, M. Niiyama, L. Pesántez, V. Trusov, Andrey Sokolov, S. Shinomiya, Byeong Rok Ko, M. Feindt, I. Nakamura, V. Babu, Hui Li, Jingxu Wang, T. Aushev, O. Frost, Z. Suzuki, J. Grygier, J. H. Kang, Y. Miyachi, Hikaru Kawai, M. Belhorn, Benjamin Schwenker, T. Zivko, Y. B. Hsiung, K. Neichi, A. Zupanc, C. C. Zhang, E. Nakano, Antonio Limosani, T. Ferber, D. H. Lee, H. Kakuno, H. Shibuya, M. Watanabe, L. S. Peak, C. Niebuhr, O. Nitoh, K. Nishimura, Chawon Park, A. Loos, J. C. Dingfelder, M. V. Purohit, P. Goldenzweig, Rupert Leitner, V. V. Zhulanov, J. Yamaoka, Xiuwan Li, K. Senyo, S. Eidelman, L. Shang, Ihn Sik Seong, S. Sandilya, K. Ueno, M. Heck, M. J. Kim, T. Kawasaki, P. Pakhlov, W. Ostrowicz, U. Tamponi, Anton Poluektov, T. Schlüter, S. Sugihara, M. Starič, Y. Igarashi, M. Masuda, Dipanwita Dutta, A. Sugiyama, T. Kumita, M. Uchida, X. H. He, D. Cinabro, Philip Lewis, G. B. Mohanty, C. H. Li, Massimo Berger, B. H. Kim, Y. Yook, H. Yamamoto, L. K. Li, V.N. Zhilich, Y. Kato, V. Chobanova, Y. Kuroki, Satoshi Tanaka, D. Liventsev, Y. Arita, I. Jaegle, K. Miyabayashi, M. Lubej, G. Inguglia, I. Badhrees, Y. Koga, E. Nedelkovska, F. Breibeck, H. Park, J. Stypula, C. Kiesling, E. J. White, A. Bozek, P. Chang, G. S. Varner, Y.-T. Lai, K. Suzuki, P. Schonmeier, M. Iwabuchi, R. Mussa, H. B. Jeon, O. Grzymkowska, C. H. Wang, M. Grosse Perdekamp, R. Itoh, Jung-Hyun Kim, S. Wehle, T. Keck, S. Paul, L. Li Gioi, Y. Yamashita, C. Z. Yuan, Yukinori Sato, J. G. Shiu, M. Nayak, T. Bloomfield, A. Ishikawa, A. Drutskoy, S. E. Vahsen, A. Bay, C.-L. Hsu, T. Saito, S. Rummel, T. Matsuda, Yu Nakahama, M. Tanaka, T. Peng, G. Schnell, A. Rostomyan, Tsukasa Aso, P. Wang, H. Miyata, Y. Hoshi, M. Barrett, B. Bhuyan, Y.L. Han, A. Frey, H. Ye, P. Križan, T. Iijima, Jun Sasaki, H. G. Moser, M. Bračko, Y. Iwasaki, B. G. Fulsom, Peter Kodys, W. W. Jacobs, T. E. Browder, Y. J. Kwon, K. Nakamura, Ya-Qiu Jin, P. Hamer, K. Hayasaka, A. Bobrov, H. Hayashii, Hyunyong Kim, O. Schneider, K. Prasanth, M. Imamura, T. Nagamine, K. Trabelsi, P. Katrenko, T. Müller, J. Klucar, K. T. Kim, C. P. Shen, S. Di Carlo, Seok Kim, S. Okuno, B. Shwartz, Jamal Rorie, D. Getzkow, C. B. Van Hulse, I. Adachi, A. Ogawa, K. Negishi, T. Kuhr, D. Z. Besson, E. Ribežl, D. Santel, Phillip Urquijo, N. Sasao, Victoria Zhukova, V. Savinov, M. Danilov, H. Nakayama, D. Y. Kim, R. Gillard, R. Mizuk, Eberhard Widmann, J. F. Strube, Matthew Jones, M. Z. Wang, K. Kinoshita, M. Yamauchi, G. Bonvicini, Y. B. Li, Y. Teramoto, I. Tikhomirov, D. Mohapatra, J. B. Singh, A. Chen, K. Hara, S. K. Choi, Sanmay Ganguly, T. Uchida, Y. Ban, N. Zwahlen, Bruce Yabsley, L. Zhao, M. Heider, M. Rozanska, D. Kotchetkov, Y. Yusa, A. Vinokurova, S. Dubey, Rahul Kumar, J. Libby, R. Louvot, Y. Chao, G. N. Taylor, R. Glattauer, V.E. Shebalin, J. Haba, W. Bartel, S. Nishida, S. Al Said, K. Hoshina, Y. Seino, Y. Onuki, K. Vervink, Z. Drásal, Marko Petrič, M. T. Prim, K. Itagaki, Z. Q. Liu, C. Bookwalter, B. G. Cheon, H. J. Hyun, S. Uozumi, P. Smerkol, Tariq Aziz, X. L. Wang, D. Heffernan, T. Morii, C. Boulahouache, J. Hasenbusch, V. Chekelian, J. Li, V. M. Aulchenko, H. Guo, T.-A. Shibata, T. Horiguchi, Y. Ono, S. Koblitz, Seema Bahinipati, Y. Choi, H. Takeichi, K. J. Nath, S. Uno, C. Schwanda, P. Krokovny, M. T. Hedges, Samo Stanič, L.M. Zhang, E. Kurihara, A.E. Bondar, P.A. Lukin, T. Nakano, K. Dutta, A. Garmash, Daniel Greenwald, M. Takizawa, B. Reisert, Y. Sakai, J. Rauch, B. K. Pal, E. L. Barberio, M. Shapkin, Noritaka Shimizu, T. Hara, L. Santelj, J. Dalseno, Robin Wedd, K. M. Williams, V. Bansal, K. Belous, A. M. Bakich, S. Korpar, Jolanta Brodzicka, John Yelton, T. Ohshima, Z. Doležal, K. Chilikin, Y. J. Kim, N. Dash, S. Iwata, H. Ozaki, H. Nakano, C. Ng, K. H. Kang, K. Cho, K. Inami, M. Sumihama, A. Heller, M. D. Peters, Motoki Iwasaki, Y. Ushiroda, N. Taniguchi, Y. M. Goh, S. H. Lee, K. Prothmann, R. Pestotnik, N. Gabyshev, D. Červenkov, A. Abdesselam, M. Steder, M. E. Sevior, I. S. Lee, D. Matvienko, Y. Miyazaki, R. Sinha, P. K. Behera, Yasushi Nagasaka, B. Kronenbitter, Sumio Yamada, E. Kato, M. Leitgab, Tao Luo, K. Tanida, F. Tenchini, T. Sumiyoshi, A. Bala, D. Epifanov, Soumya D. Mohanty, C. Pulvermacher, Martin Ritter, Dmytro Levit, Z. Natkaniec, S. L. Blyth, T. Sanuki, Shigeki Hirose, K. K. Joo, Hirokazu Miyake, R. Seidl, Y. Guan, E. Solovieva, Norihito Muramatsu, M. Huschle, K. Sakai, Y. Watanabe, S. K. Kim, A.L. Sibidanov, H. Kichimi, M. C. Chang, K. S. Park, V. Bhardwaj, T. K. Pedlar, T. Tsuboyama, H. Palka, L. E. Piilonen, G. Pakhlova, J. Wiechczynski, R. Kulasiri, S. U. Kataoka, S. Yashchenko, A. Moll, S. L. Olsen, D. Joffe, T. Julius, Po-Hsun Chen, R. Chistov, A. Vossen, O. Seon, Frank Simon, D. Semmler, Y. Unno, K. F. Chen, R. Ayad, T. Nozaki, S. Uehara, M. N. Wagner, Peter Kvasnicka, A. B. Kaliyar, Sunmin Ryu, C. W. Park, E. Won, C. Oswald, H. Atmacan, P. Vanhoefer, E. Panzenböck, B. Golob, M. Schram, N. K. Nisar, H. K. Moon, J. S. Lange, M. Ziegler, K. Adamczyk, Y. Soloviev, W. S. Hou, K. Arinstein, Y. Mikami, Alexei Kuzmin, V. Vorobyev, Nagao Kobayashi, Y. F. Liu, C. Kleinwort, Z. P. Zhang, H. Sahoo, Tara Nanut, T. Uglov, Yoji Hasegawa, S. Y. Suzuki, Richard T. Kouzes, K. Sumisawa, D. M. Asner, S. Himori, Kevin Varvell, A. Matyja, Jason Crnkovic, T. Mori, H. Aihara, Y. Usov, Jyoti Prakash Biswal, C. Liu, H. Nakazawa, A. J. Schwartz, H. Farhat, J. B. Kim, T. Higuchi, S. Ogawa, V. Gaur, Y. S. Sohn, Ferdinando Giordano, M. Nakao, E. Waheed, S. McOnie, J. MacNaughton, and P. Kapusta

Subjects
Physics, Nuclear and High Energy Physics, Particle physics, 010308 nuclear & particles physics, Maximum likelihood, Electron–positron annihilation, 01 natural sciences, law.invention, Nuclear physics, KEKB, law, 0103 physical sciences, Radiative transfer, Michel parameters, Statistical analysis, 010306 general physics, Collider, Lepton
Abstract

We present the first measurement of the Michel parameters η ‾ and ξκ in the radiative leptonic decay of the τ lepton using 703 fb-1 of data collected with the Belle detector at the KEKB e + e − collider. The Michel parameters are measured by an unbinned maximum likelihood fit to the kinematic information of e + e − → τ + τ − → ( π + π 0 ν ‾ ) ( l − ν ν ‾ γ ) ( l = e or μ ) . The preliminary values of the measured Michel parameters are η ‾ = − 2.0 ± 1.5 ± 0.8 and ξ κ = 0.6 ± 0.4 ± 0.2 , where the first error is statistical and the second is systematic.

Published
2017

17. Atmospheric loss from the dayside open polar region and its dependence on geomagnetic activity: implications for atmospheric escape on evolutionary timescales

Author

R. Slapak, A. Schillings, H. Nilsson, M. Yamauchi, L.-G. Westerberg, and I. Dandouras

Subjects
lcsh:Geophysics. Cosmic physics, TheoryofComputation_ANALYSISOFALGORITHMSANDPROBLEMCOMPLEXITY, lcsh:QC801-809, lcsh:Q, lcsh:Science, lcsh:Physics, lcsh:QC1-999
Abstract

We have investigated the total O+ escape rate from the dayside open polar region and its dependence on geomagnetic activity, specifically Kp. Two different escape routes of magnetospheric plasma into the solar wind, the plasma mantle, and the high-latitude dayside magnetosheath have been investigated separately. The flux of O+ in the plasma mantle is sufficiently fast to subsequently escape further down the magnetotail passing the neutral point, and it is nearly 3 times larger than that in the dayside magnetosheath. The contribution from the plasma mantle route is estimated as ∼ 3. 9 × 1024exp(0. 45 Kp) [s−1] with a 1 to 2 order of magnitude range for a given geomagnetic activity condition. The extrapolation of this result, including escape via the dayside magnetosheath, indicates an average O+ escape of 3 × 1026 s−1 for the most extreme geomagnetic storms. Assuming that the range is mainly caused by the solar EUV level, which was also larger in the past, the average O+ escape could have reached 1027–28 s−1 a few billion years ago. Integration over time suggests a total oxygen escape from ancient times until the present roughly equal to the atmospheric oxygen content today.

Published
2017

18. DS_10.1177_0022034519828710 – Supplemental material for Aberrant Collagen Cross-linking in Human Oral Squamous Cell Carcinoma

Author

T. Saito, K. Uzawa, M. Terajima, M. Shiiba, A.L. Amelio, H. Tanzawa, and M. Yamauchi

Subjects
stomatognathic diseases, 110599 Dentistry not elsewhere classified, FOS: Materials engineering, FOS: Clinical medicine, 91299 Materials Engineering not elsewhere classified
Abstract

Supplemental material, DS_10.1177_0022034519828710 for Aberrant Collagen Cross-linking in Human Oral Squamous Cell Carcinoma by T. Saito, K. Uzawa, M. Terajima, M. Shiiba, A.L. Amelio, H. Tanzawa and M. Yamauchi in Journal of Dental Research

Published
2019
Full Text
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19. Numerical study of plasma-fluid characteristics and thrust performance of a low-power argon inductively coupled plasma electrothermal thruster

Author

Takayasu Fujino and M. Yamauchi

Subjects
010302 applied physics, Argon, Materials science, Computer simulation, Spacecraft propulsion, Nuclear engineering, General Physics and Astronomy, chemistry.chemical_element, Thrust, 02 engineering and technology, Plasma, 021001 nanoscience & nanotechnology, 01 natural sciences, Arcjet rocket, chemistry, Physics::Plasma Physics, Physics::Space Physics, 0103 physical sciences, Magnetohydrodynamic drive, Inductively coupled plasma, 0210 nano-technology
Abstract

Low-power (from the sub-kilowatt range up to a few kilowatts) inductively coupled plasma (ICP) electrothermal thrusters for space propulsion are potential alternatives to low-power arcjet thrusters, which are often implemented on geostationary satellites for north–south station keeping. We develop an axisymmetric two-dimensional magnetohydrodynamic (MHD) numerical simulation technique using a two-temperature plasma model as a computer-aided engineering tool for low-power argon ICP electrothermal thrusters. Furthermore, to the best of our knowledge, this is the first study to provide a basic understanding of the plasma-fluid characteristics of low-power ICP electrothermal thrusters. To this end, we perform the MHD numerical simulation for a low-power argon ICP electrothermal thruster model that was developed for thrust measurement experiments to validate the proposed numerical simulation technique. The numerical results indicate that the plasma flow produced in the low-power argon ICP electrothermal thruster model is basically in a strongly thermal and ionizing nonequililbrium state. In addition, the numerical results show that the experimentally measured thrust forces can be reproduced with an underestimation of 10% or less over the RF input power range of 0–0.6 kW considered in the experiment. Moreover, the numerical results suggest that the main reason why the performance of the low-power argon ICP electrothermal thruster model is significantly lower than the target performance is the considerable heat loss of more than 90% of the input power through the flow-channel wall.

Published
2020

20. Characteristics of high altitude oxygen ion energization and outflow as observed by Cluster: a statistical study

Author

H. Nilsson, M. Waara, S. Arvelius, O. Marghitu, M. Bouhram, Y. Hobara, M. Yamauchi, R. Lundin, H. Rème, J.-A. Sauvaud, I. Dandouras, A. Balogh, L. M. Kistler, B. Klecker, C. W. Carlson, M. B. Bavassano-Cattaneo, A. Korth, Swedish Institute of Space Physics [Kiruna] (IRF), Max-Planck-Institut für Extraterrestrische Physik (MPE), Institute of Space Science [Bucharest-Măgurele] (ISS), Centre d'étude spatiale des rayonnements (CESR), Observatoire Midi-Pyrénées (OMP), Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées, Imperial College of Science, University of New Hampshire (UNH), Space Sciences Laboratory [Berkeley] (SSL), University of California [Berkeley], University of California-University of California, Istituto di Fisica dello Spazio Interplanetario (IFSI), Consiglio Nazionale delle Ricerche (CNR), Max-Planck-Institut für Sonnensystemforschung (MPS), Max-Planck-Gesellschaft, Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), University of California [Berkeley] (UC Berkeley), University of California (UC)-University of California (UC), National Research Council of Italy | Consiglio Nazionale delle Ricerche (CNR), and Max-Planck-Institut für Sonnensystemforschung = Max Planck Institute for Solar System Research (MPS)

Subjects
Atmospheric Science, Materials science, 010504 meteorology & atmospheric sciences, Magnetosphere, [SDU.STU]Sciences of the Universe [physics]/Earth Sciences, Champ magnetique, Atmospheric sciences, 01 natural sciences, TheoryofComputation_ANALYSISOFALGORITHMSANDPROBLEMCOMPLEXITY, 0103 physical sciences, Earth and Planetary Sciences (miscellaneous), Oxygen ions, Cluster (physics), lcsh:Science, 010303 astronomy & astrophysics, 0105 earth and related environmental sciences, [SDU.OCEAN]Sciences of the Universe [physics]/Ocean, Atmosphere, lcsh:QC801-809, Geology, Astronomy and Astrophysics, Effects of high altitude on humans, lcsh:QC1-999, Solar wind, lcsh:Geophysics. Cosmic physics, 13. Climate action, Space and Planetary Science, Magnetopause, Outflow, lcsh:Q, lcsh:Physics
Abstract

The results of a statistical study of oxygen ion outflow using Cluster data obtained at high altitude above the polar cap is reported. Moment data for both hydrogen ions (H+) and oxygen ions (O+) from 3 years (2001-2003) of spring orbits (January to May) have been used. The altitudes covered were mainly in the range 5–12 RE geocentric distance. It was found that O+ is significantly transversely energized at high altitudes, indicated both by high perpendicular temperatures for low magnetic field values as well as by a tendency towards higher perpendicular than parallel temperature distributions for the highest observed temperatures. The O+ parallel bulk velocity increases with altitude in particular for the lowest observed altitude intervals. O+ parallel bulk velocities in excess of 60 km s-1 were found mainly at higher altitudes corresponding to magnetic field strengths of less than 100 nT. For the highest observed parallel bulk velocities of O+ the thermal velocity exceeds the bulk velocity, indicating that the beam-like character of the distribution is lost. The parallel bulk velocity of the H+ and O+ was found to typically be close to the same throughout the observation interval when the H+ bulk velocity was calculated for all pitch-angles. When the H+ bulk velocity was calculated for upward moving particles only the H+ parallel bulk velocity was typically higher than that of O+. The parallel bulk velocity is close to the same for a wide range of relative abundance of the two ion species, including when the O+ ions dominates. The thermal velocity of O+ was always well below that of H+. Thus perpendicular energization that is more effective for O+ takes place, but this is not enough to explain the close to similar parallel velocities. Further parallel acceleration must occur. The results presented constrain the models of perpendicular heating and parallel acceleration. In particular centrifugal acceleration of the outflowing ions, which may provide the same parallel velocity increase to the two ion species and a two-stream interaction are discussed in the context of the measurements.

Published
2018

21. Transients in oxygen outflow above the polar cap as observed by the Cluster spacecraft

Author

H. Nilsson, M. Waara, O. Marghitu, M. Yamauchi, R. Lundin, H. Rème, J.-A. Sauvaud, I. Dandouras, E. Lucek, L. M. Kistler, B. Klecker, C. W. Carlson, M. B. Bavassano-Cattaneo, and A. Korth

Subjects
Physics, Convection, Atmospheric Science, lcsh:QC801-809, Incoherent scatter, Flux, Geology, Astronomy and Astrophysics, Geophysics, Astrophysics, Escape velocity, Effects of high altitude on humans, lcsh:QC1-999, lcsh:Geophysics. Cosmic physics, Space and Planetary Science, Physics::Space Physics, Earth and Planetary Sciences (miscellaneous), Magnetopause, Astrophysics::Solar and Stellar Astrophysics, Outflow, lcsh:Q, Ionosphere, lcsh:Science, lcsh:Physics
Abstract

Oxygen ion outflow associated with the cusp and cleft give rise to persistent oxygen ion beams which can be observed over the polar cap. For high altitude spacecraft such as Cluster these beams are often observed for several hours on each occasion. This allows for a study of typical temporal structures on the time scale of minutes. We have used 3 years of data from spring, January to May of years 2001 to 2003, for a study of the oxygen number flux variation in the polar cap ion outflow. The source of these oxygen ion beams is the cusp and cleft, and variations in ionospheric upflow on time scales of around 8 min have been reported from ground based studies using incoherent scatter radar. Such upflows typically do not reach escape velocity, and further energization above the ionosphere is required for outflow to occur. Our study shows that a typical time scale between sudden number flux enhancements observed by Cluster in a geocentric distance range of 5 RE to 12 RE is 5 to 10 min. A superposed epoch study does not reveal any significant convection velocity or temperature changes around the flux enhancement events. Sudden temperature enhancements occur with a typical time interval of about 4 min, A superposed epoch study does not reveal any number flux enhancements associated with the temperature enhancements. The clear modulation of the high altitude number flux in a manner which resembles the modulation of the ionospheric upflow indicates that this is the main limiting factor determining the total outflow. The process behind transient upflow events in the ionosphere is therefore important for the total ionospheric outflow. Subsequent heating above the ionosphere appears to be common enough in the cusp/cleft region that it does not significantly modulate the oxygen ion number flux.

Published
2018

23. SHAPE ESTIMATION OF BOWTIE FILTERS BASED ON THE LUMINESCENCE FROM POLYETHYLENE TEREPHTHALATE RESIN BY X-RAY IRRADIATION

Author

M Yamauchi, Seiichi Yamamoto, N Suga, Nobuhiro Ito, M Kozuka, Keisuke Fujii, Chiyo Yamauchi-Kawaura, and N Ohzawa

Subjects
Scanner, Materials science, Luminescence, Tomography Scanners, X-Ray Computed, chemistry.chemical_element, Radiation Dosage, Luminance, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Optics, Aluminium, Polyethylene terephthalate, Image Processing, Computer-Assisted, Humans, Radiology, Nuclear Medicine and imaging, Computer Simulation, Irradiation, Radiometry, Radiation, Radiological and Ultrasound Technology, business.industry, Phantoms, Imaging, Polyethylene Terephthalates, Attenuation, X-Rays, Public Health, Environmental and Occupational Health, General Medicine, Equipment Design, chemistry, Filter (video), 030220 oncology & carcinogenesis, Positron-Emission Tomography, business, Tomography, X-Ray Computed, Head, Monte Carlo Method, Aluminum
Abstract

In this study, we devised a novel method estimating the bowtie filter shapes by imaging luminescence from a polyethylene terephthalate (PET) resin with X-ray irradiation in a computed tomography (CT) scanner. The luminescence distribution of the PET resin corresponding to the thickness of bowtie filter was imaged using a charge-coupled device camera. On the assumption that the material of bowtie filter is aluminium (Al), the shape of bowtie filters was estimated from the correlation between Al attenuation curves and the angular-dependent luminance attenuation profiles according to the thickness of bowtie filters. Dose simulations based on the estimated bowtie filter shapes were performed using head and body PMMA phantoms with 16 and 32 cm in diameter. The simulated values of head and body weighted CT dose index (CTDIw) based on bowtie filter shape by the luminescence imaging method agreed within ~9% with the measured values by a dosemeter.

Published
2018

24. Analysis of the effect of seasonal climate changes on cooling tower efficiency, and strategies for reducing cooling tower power consumption

Author

Willian M. Yamauchi, Evelin K.G. Silva, and Ricardo F.F. Pontes

Subjects
Meteorology, 020209 energy, Electric potential energy, Energy Engineering and Power Technology, Climate change, 02 engineering and technology, Industrial and Manufacturing Engineering, Cost reduction, Design phase, 020401 chemical engineering, Volume (thermodynamics), Power consumption, 0202 electrical engineering, electronic engineering, information engineering, Water cooling, Environmental science, Cooling tower, 0204 chemical engineering
Abstract

Cooling towers are widely used in chemical industries to cool water with ambient air that is susceptible to weather changes not only during the day, but also during the year, resulting in challenges to cooling towers design and operation. In the design phase, the difficulties to determine the cooling tower capacity arise not only from the uncertainty of cooling water consumption but also from ambient temperature variations, which have a direct impact on the volume of cooling tower fill and fan power. Wide temperature variations can result in cooling towers that excessively cool water during significant portion of the year. Moreover, an oversized cooling tower brings challenges to the plant operation, since the cooling tower turndown must be high to account for the colder days. The mathematical model of cooling tower operation that is composed by mass and energy balances, and by cooling tower characteristic equations can be simulated to design cooling towers, and forecast their performances in four Brazilian cities (Manaus, Salvador, Sao Paulo and Porto Alegre). Analyzing the results enables the calculation of the cooling tower slack, and the required turndown during the year in these four cities. This work proposes strategies for cooling tower fan operation to reduce the slack, and estimates the electrical energy cost reduction if such strategies are implemented.

Published
2019

25. Randomised clinical trial: prevention of recurrence of peptic ulcers by rabeprazole in patients taking low-dose aspirin

Author

M. Yamauchi, Ryuichi Iwakiri, T. Arakawa, M. Sanomura, Toshio Watanabe, Nobuyuki Sugisaki, Kazuma Fujimoto, Masako Kato, Yoshikazu Kinoshita, H. Nakagawa, Kazuhide Higuchi, Toshihisa Takeuchi, Y. Okada, Mitsuhiro Fujishiro, and Hisao Ogawa

Subjects
medicine.medical_specialty, Aspirin, Hepatology, business.industry, Peptic, Gastroenterology, Rabeprazole, Clinical trial, Internal medicine, medicine, Clinical endpoint, Pharmacology (medical), Teprenone, In patient, business, medicine.drug, Low dose aspirin
Abstract

SummaryBackground Few studies have evaluated the effects of rabeprazole on low-dose aspirin (LDA)-induced gastroduodenal injuries. Aim To conduct a randomised, double-blind, triple-dummy, active-controlled, multicentre trial, named the PLANETARIUM study, to assess the efficacy, dose–response relationship and safety of rabeprazole for peptic ulcer recurrence in Japanese patients on long-term LDA therapy. Methods Eligible patients had a history of endoscopically confirmed peptic ulcers and were receiving long-term LDA (81 or 100 mg/day) therapy for cardiovascular or cerebrovascular protection. Subjects were randomly segregated into three groups receiving rabeprazole 10 mg once daily (standard dose in Japan), rabeprazole 5 mg once daily, or teprenone (geranylgeranylacetone; mucosal protective agent commercially available in Japan) 50 mg three times per day as an active control. The primary endpoint was recurrence of peptic ulcers over 24 weeks. Results Among 472 randomised subjects, 452 subjects (n = 151, 150, 151, respectively) constituted the full analysis set. The cumulative recurrence rates of peptic ulcers over 24 weeks in the 10- and 5-mg rabeprazole groups were 1.4% and 2.8%, respectively, both of which were significantly lower than that in the teprenone group (21.7%). The cumulative occurrence rate of bleeding ulcers over 24 weeks in the teprenone group was 4.6%, while bleeding ulcers were not observed in the 10- or 5-mg rabeprazole groups. Rabeprazole was well tolerated at both doses. Conclusion Rabeprazole prevents the recurrence of peptic ulcers with no evidence of a major dose–response effect in subjects on low-dose aspirin therapy.

Published
2014

26. C5-Symmetric Chiral Corannulenes: Desymmetrization of Bowl Inversion Equilibrium via 'Intramolecular' Hydrogen-Bonding Network

Author

Yoshihisa Inoue, Daigo Miyajima, Soichiro Harada, Tadashi Mori, Hiroki Tanaka, M. Yamauchi, Takuzo Aida, Jiheong Kang, and Yoshimitsu Itoh

Subjects
Hydrogen bond, Stereochemistry, General Chemistry, Biochemistry, Desymmetrization, Catalysis, chemistry.chemical_compound, Colloid and Surface Chemistry, chemistry, Corannulene, Amide, Intramolecular force, Side chain, Methylcyclohexane, Enantiomer
Abstract

Because of a rapid conformational inversion, bowl-shaped C5-symmetric corannulenes, though geometrically chiral, have not been directly resolved into their enantiomers. However, if this inversion equilibrium can be desymmetrized, chiral corannulenes enriched in either enantiomer can be obtained. We demonstrated this possibility using pentasubstituted corannulenes 4 and 5 carrying amide-appended thioalkyl side chains. Compound 4 displays chiroptical activity in a chiral hydrocarbon such as limonene. Because compound 5 carries a chiral center in the side chains, its enantiomers 5R and 5S show chiroptical activity even in achiral solvents such as CHCl3 and methylcyclohexane. In sharp contrast, when the side chains bear no amide functionality (1 and 2R), no chiroptical activity emerges even in limonene or with a chiral center in the side chains. Detailed investigations revealed that the peripheral amide units in 4 and 5 are hydrogen-bonded only “intramolecularly” along the corannulene periphery, affording cyc...

Published
2014

27. Manipulating γ-cyclodextrin-mediated photocyclodimerization of anthracenecarboxylate by wavelength, temperature, solvent and host

Author

Qian Wang, Gaku Fukuhara, Yoshihisa Inoue, Jabing Yao, Da-Yang Zhou, Cheng Yang, Yu Liu, M. Yamauchi, Tadashi Mori, and Masaki Nishijima

Subjects
Anthracenes, Models, Molecular, Chemistry, Carboxylic Acids, Molecular Conformation, Temperature, Stacking, Stereoisomerism, Photochemical Processes, Photochemistry, Solvent, Wavelength, Cyclization, Solvents, Irradiation, Physical and Theoretical Chemistry, Enantiomer, Ground state, Enantiomeric excess, Selectivity, Dimerization, gamma-Cyclodextrins
Abstract

Wavelength effects on the enantiodifferentiating photocyclodimerization of 2-anthracenecarboxylate (AC) mediated by native and modified γ-cyclodextrins (CDs) were examined in different solvents at varying temperatures to manipulate the photochirogenic outcomes beyond the thermodynamically determined re/si-enantiotopic face selectivity upon 2 : 1 complexation of AC with CD in the ground state. Indeed, the stereochemical outcomes, i.e. syn/anti, head-to-tail/head-to-head (HT/HH) and in particular enantiomer ratios, were critical functions of the irradiation wavelength, irrespective of the CD host employed. Furthermore, the wavelength effects observed strongly depended on the host structure, reaction temperature and solvent employed, for which altered stacking geometry of the complexed AC pair is thought to be responsible. By optimizing the irradiation wavelength, chiral host, temperature and solvent, an enantiomeric excess of up to 54 and -37% were achieved for chiral syn-HT and anti-HH dimers.

Published
2014

28. Image quality and age-specific dose estimation in head and chest CT examinations with organ-based tube-current modulation

Author

Takahiko Aoyama, Kuniharu Imai, M Yamauchi, Mitsuru Ikeda, and Chiyo Yamauchi-Kawaura

Subjects
Adult, medicine.medical_specialty, Image quality, Entropy, Radiography, Chest ct, Radiation Dosage, Lens, Crystalline, Dose estimation, medicine, Image noise, Humans, Dosimetry, Radiology, Nuclear Medicine and imaging, Child, Radiometry, Skin, Radiation, Radiological and Ultrasound Technology, Phantoms, Imaging, business.industry, Age Factors, Infant, Newborn, Public Health, Environmental and Occupational Health, General Medicine, Image Enhancement, Age specific, Radiographic Image Interpretation, Computer-Assisted, Radiography, Thoracic, Radiology, Tomography, Tomography, X-Ray Computed, business, Head
Abstract

The purpose of this study was to investigate the effects of an organ-based tube-current modulation (OBTCM) system on image quality and age-specific dose in head and chest CT examinations. Image noise, contrast-to-noise ratio (CNR) and image entropy were assessed using statistical and entropy analyses. Radiation doses for newborn, 6-y-old child and adult phantoms were measured with in-phantom dosimetry systems. The quality of CT images obtained with OBTCM was not different from that obtained without OBTCM. In head CT scans, the eye lens dose decreased by 20-33 % using OBTCM. In chest CT scans, breast dose decreased by 5-32 % using OBTCM. Posterior skin dose, however, increased by 11-20 % using OBTCM in head and chest CT scans. The reduction of effective dose using OBTCM was negligibly small. Detailed image quality and dose information provided in this study can be effectively used for OBTCM application.

Published
2013

29. Impact of Blood Pressure Control on Thromboembolism and Major Hemorrhage in Patients With Nonvalvular Atrial Fibrillation: A Subanalysis of the J‐RHYTHM Registry

Author

Eitaro Kodani, Hirotsugu Atarashi, Hiroshi Inoue, Ken Okumura, Takeshi Yamashita, Toshiaki Otsuka, Hirofumi Tomita, Hideki Origasa, M. Sakurai, Y. Kawamura, I. Kubota, Y. Kaneko, K. Matsumoto, S. Ogawa, Y. Aizawa, I. Kodama, E. Watanabe, Y. Koretsune, Y. Okuyama, A. Shimizu, O. Igawa, S. Bando, M. Fukatani, T. Saikawa, A. Chishaki, N. Kato, K. Kanda, J. Kato, H. Obata, M. Aoki, H. Honda, Y. Konta, T. Hatayama, Y. Abe, K. Terata, T. Yagi, A. Ishida, T. Komatsu, H. Tachibana, H. Suzuki, Y. Kamiyama, T. Watanabe, M. Oguma, M. Itoh, O. Hirono, Y. Tsunoda, K. Ikeda, T. Kanaya, K. Sakurai, H. Sukekawa, S. Nakada, T. Itoh, S. Tange, M. Manita, M. Ohta, H. Eguma, R. Kato, Y. Endo, T. Ogino, M. Yamazaki, H. Kanki, M. Uchida, S. Miyanaga, K. Shibayama, N. Toratani, T. Kojima, M. Ichikawa, M. Saito, Y. Umeda, T. Sawanobori, H. Sohara, S. Okubo, T. Okubo, T. Tokunaga, O. Kuboyama, H. Ito, Y. Kitahara, K. Sagara, T. Satoh, K. Sugi, Y. Kobayashi, Y. Higashi, T. Katoh, Y. Hirayama, N. Matsumoto, M. Takano, T. Ikeda, S. Yusu, S. Niwano, Y. Nakazato, Y. Kawano, M. Sumiyoshi, N. Hagiwara, K. Murasaki, H. Mitamura, S. Nakagawa, K. Okishige, K. Azegami, H. Aoyagi, K. Sugiyama, M. Nishizaki, N. Yamawake, I. Watanabe, K. Ohkubo, H. Sakurada, S. Fukamizu, M. Suzuki, W. Nagahori, T. Nakamura, Y. Murakawa, N. Hayami, K. Yoshioka, M. Amino, K. Hirao, A. Yagishita, K. Ajiki, K. Fujiu, Y. Imai, A. Yamashina, T. Ishiyama, M. Sakabe, K. Nishida, H. Asanoi, H. Ueno, J. D. Lee, Y. Mitsuke, H. Furushima, K. Ebe, M. Tagawa, M. Sato, M. Morikawa, K. Yamashiro, K. Takami, T. Ozawa, M. Watarai, M. Yamauchi, H. Kamiya, H. Hirayama, Y. Yoshida, T. Murohara, Y. Inden, H. Osanai, N. Ohte, T. Goto, I. Morishima, T. Yamamoto, E. Fujii, M. Senga, H. Hayashi, T. Urushida, Y. Takada, N. Tsuboi, T. Noda, T. Hirose, T. Onodera, S. Kageyama, T. Osaka, T. Tomita, K. Shimada, M. Nomura, H. Izawa, A. Sugiura, T. Arakawa, K. Kimura, T. Mine, T. Makita, H. Mizuno, A. Kobori, T. Haruna, M. Takagi, N. Tanaka, H. Shimizu, T. Kurita, K. Motoki, N. Takeda, Y. Kijima, M. Ito, A. Nakata, Y. Ueda, A. Hirata, S. Kamakura, K. Satomi, Y. Yamada, Y. Yoshiga, H. Ogawa, M. Kimura, T. Hayano, T. Kinbara, H. Tatsuno, M. Harada, K. F. Kusano, M. Adachi, A. Yano, M. Sawaguchi, J. Yamasaki, T. Matsuura, Y. Tanaka, H. Moritani, T. Maki, S. Okada, M. Takechi, T. Hamada, A. Nishikado, Y. Takagi, I. Matsumoto, T. Soeki, Y. Doi, M. Okawa, H. Seo, S. Kitamura, K. Yamamoto, M. Akizawa, N. Kaname, S. Ando, S. Narita, T. Inou, Y. Fukuizumi, K. Saku, M. Ogawa, Y. Urabe, M. Ikeuchi, S. Harada, H. Yamabe, Y. Imamura, Y. Yamanouchi, K. Sadamatsu, K. Yoshida, T. Kubota, N. Takahashi, N. Makino, Y. Higuchi, T. Ooie, T. Iwao, K. Kitamura, T. Imamura, K. Maemura, N. Komiya, M. Hayano, H. Yoshida, and K. Kumagai

Subjects
Male, medicine.medical_specialty, lcsh:Diseases of the circulatory (Cardiovascular) system, hypertension, medicine.drug_class, Diastole, Hemorrhage, 030204 cardiovascular system & hematology, 03 medical and health sciences, 0302 clinical medicine, Japan, Risk Factors, Internal medicine, Odds Ratio, Medicine, Humans, Arrhythmia and Electrophysiology, atrial fibrillation, 030212 general & internal medicine, Prospective Studies, Registries, Risk factor, Antihypertensive drug, anticoagulation, Antihypertensive Agents, Original Research, Ischemic Stroke, Intracranial Hemorrhage, Aged, Proportional Hazards Models, business.industry, Hazard ratio, Warfarin, blood pressure, Atrial fibrillation, Odds ratio, Middle Aged, thromboembolism, medicine.disease, Blood pressure, High Blood Pressure, lcsh:RC666-701, Cardiology, Female, Cardiology and Cardiovascular Medicine, business, medicine.drug
Abstract

Background To clarify the influence of hypertension and blood pressure ( BP ) control on thromboembolism and major hemorrhage in patients with nonvalvular atrial fibrillation, a post hoc analysis of the J‐ RHYTHM Registry was performed. Methods and Results A consecutive series of outpatients with atrial fibrillation was enrolled from 158 institutions. Of 7937 patients, 7406 with nonvalvular atrial fibrillation (70.8% men, 69.8±10.0 years) were followed for 2 years or until an event occurred. Hypertension was defined as a systolic BP ≥140 mm Hg, a diastolic BP ≥90 mm Hg, a history of hypertension, and/or antihypertensive drug use. Hypertension was an independent risk factor for major hemorrhage (hazard ratio 1.52, 95% CI 1.05–2.21, P =0.027) but not for thromboembolism (hazard ratio 1.05, 95% CI 0.73–1.52, P =0.787). When patients were divided into quartiles according to their systolic BP at the time closest to the event or at the end of follow‐up (Q1, CI 1.75–4.74, P CI 1.02–2.53, P =0.041) after adjustment for components of CHA 2 DS 2 ‐ VAS c score, warfarin use, and antiplatelet use. A systolic BP of ≥136 mm Hg was an independent risk factor for thromboembolism and major hemorrhage. Conclusions BP control appears to be more important than a history of hypertension and baseline BP values at preventing thromboembolism and major hemorrhage in patients with nonvalvular atrial fibrillation. Clinical Trial Registration URL : http://www.umin.ac.jp/ctr . Unique identifier: UMIN 000001569.

Published
2016

31. Evaluation of organ doses in CT examinations with an infant anthropomorphic phantom

Author

T. Horiuchi, Toshio Kawasaki, O. Miyazaki, Keiichi Akahane, A. Shimada, Keisuke Fujii, H. Nagmatsu, M Yamauchi, and Chiyo Yamauchi-Kawaura

Subjects
medicine.medical_specialty, Tomography Scanners, X-Ray Computed, Adolescent, Radiography, Chest ct, Radiation Dosage, Pelvis, X ray computed, medicine, Humans, Radiology, Nuclear Medicine and imaging, Child, Radiometry, CT protocol, Radiation, Anthropometry, Radiological and Ultrasound Technology, Phantoms, Imaging, business.industry, Public Health, Environmental and Occupational Health, Infant, General Medicine, Multicenter study, Child, Preschool, Ct scanners, Body Burden, Radiography, Thoracic, Anthropomorphic phantom, Radiology, Tomography, Tomography, X-Ray Computed, business, Head
Abstract

The aim of this study is to evaluate organ doses in infant CT examinations with multi-detector row CT scanners. Radiation doses were measured with radiophotoluminescence glass dosemeters set in various organ positions within a 1-y-old child anthropomorphic phantom and organ doses were evaluated from the measurement values. Doses for tissues or organs within the scan range were 28-36 mGy in an infant head CT, 3-11 mGy in a chest CT, 5-11 mGy in an abdominal-pelvic CT and 2-14 mGy in a cardiac CT. The doses varied by the differences in the types of CT scanners and scan parameters used at each medical facility. Compared with those for children of various ages, the doses in an infant CT protocol were found to be similar to or slightly smaller than those in a paediatric CT for 5- or 6-y-old children.

Published
2011

32. Magnetically Jointed Module Manipulators: New Concept for Safe Intravehicular Activity in Space Vehicles

Author

Shinichi Kimura, M. Yamauchi, and Y. Ozawa

Subjects
Engineering, Collision avoidance (spacecraft), business.industry, Aerospace Engineering, Control engineering, Mobile robot, Space (commercial competition), Contact force, Robot, Aerospace robotics, Electrical and Electronic Engineering, Manipulator, business, Simulation
Abstract

Robots for intravehicular (IVA) support are being studied for their potential to reduce the workload of astronauts. IVA support robots must meet strict safety requirements, and they need to be compact to share limited room with astronauts. A magnetically jointed module manipulator (MagMo) solves these problems in a unique manner. The manipulator is not harmful when it contacts humans unexpectedly, because it disassembles by contact force, and it can be easily assembled only when it is needed. In this paper, the basic concept of the MagMo is introduced.

Published
2011

33. Space radiation damage to HDTV camera CCDs onboard the international space station

Author

Aiko Nagamatsu, J. Yamazaki, H. Tawara, M. Yamauchi, A. Yokota, K. Murakami, H. Kumagai, and K. Kitajo

Subjects
Physics, Radiation, Dosimeter, Pixel, business.industry, Image quality, Detector, Particle detector, PADLES, HDTV, CCD, White defect, Space radiation, CR-39 PNTD, TLD, Optics, International Space Station, Professional video camera, Optoelectronics, Thermoluminescent dosimeter, business, Instrumentation
Abstract

The image quality of high-definition television (HDTV) cameras and camcorders for space activity is degraded by the presence of permanent bright pixels (so-called “white defects”) due to space radiation. We studied the space radiation damage to HDTV charge-coupled devices (CCDs; 2 × 106 pixels per chip) loaded in the Russian service module (SM) of the International Space Station (ISS) for 71 days, 256 days and 446 days. We used the “Passive Dosimeter for Lifescience Experiments in Space” (PADLES), which consists of CR-39 plastic nuclear track detectors (PNTDs) and thermoluminescent dosimeters, to measure space radiation doses received by the HDTV CCDs in the SM during loading periods. The average production rates of white defects for output voltage greater than 0.5 mV were 2.366 ± 0.055 pixels/day in Si and 5.213 ± 0.071 pixels/mGy in Si. We also investigated the correlation between the position of the white defects and tracks of high-energy particles with LET∞,Si of approximately 300 keV/μm or more using stacks of CR-39 PNTDs and the HDTV CCD chips. We found that approximately 30% of these high-energy high-LET particles coincided with the position of white defects on the HDTV CCDs in the SM.

Published
2011

34. Radiation dose evaluation in multidetector-row CT imaging for acute stroke with an anthropomorphic phantom

Author

M Yamauchi, Shuji Koyama, C Yamauchi-Kawara, Takahiko Aoyama, and Keisuke Fujii

Subjects
medicine.medical_specialty, Perfusion scanning, Radiation Dosage, Effective dose (radiation), medicine, Humans, Dosimetry, Radiology, Nuclear Medicine and imaging, Equipment Safety, Full Paper, medicine.diagnostic_test, Phantoms, Imaging, business.industry, Radiation dose, Brain, Reproducibility of Results, General Medicine, Cerebral Angiography, Stroke, Radiological weapon, Angiography, Body Burden, Radiology, Tomography, Tomography, X-Ray Computed, Nuclear medicine, business, Cerebral angiography
Abstract

This study evaluated radiation dose and dose reduction in CT imaging for acute stroke. Radiation doses in three types of CT imaging (i.e. non-contrast-enhanced CT, CT perfusion (CTP) and CT angiography (CTA)) were measured with an in-phantom dosimetry system for 4-, 16- and 64-detector CT scanners in 5 hospitals. To examine the relationship between image quality and radiation dose in CTA, image contrast-to-noise ratio was evaluated. Doses to the brain, lens, salivary glands and local skin obtained with scan protocols in routine use were: 42–71 mGy, 30–88 mGy, 3.9–7.3 mGy and 40–97 mGy in non-contrast-enhanced CT; 41–75 mGy, 9.9–10 mGy, 1.5–2.1 mGy and 107–143 mGy in CTP; and 8.2–55 mGy, 26–69 mGy, 2.0–73 mGy and 32–72 mGy in CTA. For the combination of these CT examinations, on average a patient would receive 236 mGy for the maximum local skin dose and 4.2 mSv for the effective dose evaluated by the International Commission on Radiological Protection (ICRP) 103. Effective doses in CTP in this study were less than those obtained with representative protocols of Western countries. Average effective doses in each CT examination were not more than 1.5 mSv. The use of reduced kV and a narrow scan range would be effective in dose reduction of CTA and CTP, and intermittent scanning would be essential in CTP. Although lens and maximum local skin doses were far less than the thresholds for deterministic effects, since radiation risks would be increased in repeated CT examinations, efforts should be devoted to dose reduction in stroke CT examinations.

Published
2010

35. Abstracts

Author

O. Barthelemy, J. Silvain, D. Brieger, A. Bellemain-Appaix, G. Cayla, F. Beygui, R. Lancar, J. P. Collet, A. Mercadier, G. Montalescot, K. S. Cha, Y. H. Nam, J. H. Kim, S. Y. Park, T. H. Park, M. H. Kim, Y. D. Kim, H. C. Lee, M. S. Ahn, T. J. Hong, R. Blanco, F. Blanco, J. Szarfer, A. Garcia Escudero, G. Gigena, J. Gagliardi, A. Rodriguez, R. Sarmiento, S. Affatatto, M. Riccitelli, A. Petris, M. D. Datcu, C. Pop, M. Radoi, C. Arsenescu-Georgescu, I. Petrescu, L. Petrescu, L. Serban, E. Nechita, G. Tatu-Chitoiu, M. Dorobantu, I. Benedek, E. Craiu, C. Sinescu, D. D. Ionescu, C. Ginghina, B. Minescu, A. Izzo, P. Mantovani, L. Tomasi, L. Dall'oglio, S. Bonatti, R. Rosiello, M. Romano, F. Agostini, R. Zanini, Z. Y. Zhao, Y. J. Wu, J. J. Li, Y. J. Yany, H. Y. Qian, Y. D. Tang, A. T. Timoteo, A. Toste, A. Lousinha, R. Ramos, J. A. Oliveira, M. L. Ferreira, R. C. Ferreira, C. Cabades, J. L. Diez Gil, P. Aguar, D. Sanmiguel, A. Lopez-March, R. Marmol, L. Guerra, V. Girbes, J. Ferrando, A. Rincon De Arellano, L. Patricio, M. Blondal, T. Ainla, T. Marandi, J. Eha, M. M. Oliveira, M. N. Silva, P. S. Cunha, J. Feliciano, S. Silva, J. Kanovsky, P. Kala, J. Parenica, M. Poloczek, K. Prymusova, L. Kubkova, J. Spinar, D. Olinic, C. Homorodean, M. Ober, M. Olinic, C. Andrioaia, A. Condac, M. Masmoudi, B. Berdaoui, S. Labidi, C. Tapia Ballesteros, C. Hernandez Luis, M. G. Sandin, J. M. Vegas, R. Andion, N. Martinez, I. A. Gonzalez, M. Alvarado, I. J. Amat, J. A. San Roman, M. J. Garcia Gonzalez, E. Arroyo Ucar, C. Hernandez Garcia, M. Dorta Martin, F. Marrero Rodriguez, R. Dragu, M. Kapeliovich, H. Hammerman, D. Silva, N. Cortez-Dias, C. Jorge, J. Silva Marques, P. Carilho Ferreira, S. Robalo Martins, M. Almeida Ribeiro, C. Calisto, M. Fiuza, M. G. Lopes, P. Milicevic, M. Panic, I. Stankovic, D. Milicevic, T. Kalezic, S. Kafedzic, I. Ilic, M. Cerovic, B. Putnikovic, A. Neskovic, D. Rott, D. Leibowitz, Z. Monhart, J. Reissigova, H. Grunfeldova, P. Jansky, B. Valente, I. Villanueva Benito, I. Solla, E. Paredes, O. Diaz Castro, F. Calvo, J. A. Baz, A. Iniguez, A. Aleksova, R. Gerloni, R. Belfiore, C. Carriere, G. Barbati, E. Fabris, F. Possa, D. Nait, M. Milo, G. Sinagra, N. Marques, J. Mimoso, V. Gomes, R. M. Agra Bermejo, E. A. A. Emad Abu Assi, S. R. R. Sergio Raposeiras Roubin, P. C. G. Pilar Cabanas Grandio, C. P. G. Carlos Pena Gil, J. M. G. A. Jose Maria Garcia Acuna, J. R. G. J. Jose Ramon Gonzalez Juanatey, M. J. Daly, P. Scott, C. G. Owens, A. Tomlin, B. Smith, A. A. J. Adgey, L. R. Alvarez-Contreras, U. Juarez, A. Altamirano, A. Arias, A. Alvarez-San Gabriel, H. Gonzalez-Pacheco, C. Martinez-Sanchez, M. Rahnavardi, M. Keshtkar-Jahromi, H. Vakili, S. Gholamin, S. M. Razavi, T. Gilis-Januszewski, K.- P. Mellwig, M. Wiemer, J. Gilis-Januszewski, A. Peterschroeder, J. Koerfer, D. Horstkotte, M. Vrsalovic, B. Getaldic, N. Vrkic, H. Pintaric, S. Khan, B. Wasan, L. Moretti, P. Grossi, S. Silenzi, M. Testa, L. Candelori, L. N. Clementi, M. Forlini, L. Lando, M. L. Pezzuoli, P. Corradetti, G. Leurent, P. Y. Pennec, E. Filippi, B. Moquet, J. P. Hacot, P. Druelles, A. Rialan, G. Rouault, I. Coudert, H. Le Breton, S. Gevaert, F. Tromp, E. Vandecasteele, F. De Somer, Y. Van Belleghem, S. Bouchez, F. Martens, I. Herck, M. De Pauw, O. Ludka, M. Sepsi, R. Miklik, L. Dusek, D. Tomcikova, J. M. Garcia-Acuna, P. Aguiar-Souto, S. Raposeiras Roubin, R. Agra-Bermejo, M. Jacquet, E. Abu-Assi, J. R. Gonzalez-Juanatey, A. Ibatov, R. Labrova, R. Karlik, P. Lokaj, Q. She, S. B. Deng, S. H. Huang, L. J. Gu, J. I. A. N. Rong, Z. K. Wu, Y. Li, J. Zhang, L. Parascan, A. Campanile, L. Spinelli, G. Santulli, M. Ciccarelli, S. De Gennaro, E. Assante Di Panzillo, B. Trimarco, G. Iaccarino, E. Bobescu, G. Datcu, D. Dobreanu, B. Doka, J.- C. Charniot, C. Cosson, J. P. Albertini, R. Bittar, P. Giral, C. Cherfils, E. Guillerm, D. Bonnefont-Rousselot, A. Rusali, L. Cojocaru, I. Parepa, T. Koizumi, S. Iida, J. Sato, T. Kikutani, T. Muramatsu, S. Nishimura, N. Komiyama, W. P. Lee, B. B. Ong, K. Haralambos, D. Townsend, J. A. E. Rees, E. J. Williams, J. P. Halcox, I. Mcdowell, M. Damjanovic, G. Koracevic, D. Djordjevic-Radojkovic, M. Pavlovic, N. Krstic, S. Ciric-Zdravkovic, A. Stojkovic, Z. Perisic, S. Apostolovic, A. Faustino, L. Seca, S. Barra, F. Caetano, R. Providencia, J. Silva, P. Gomes, G. Costa, M. Costa, A. Leitao-Marques, A. L. Volkova, G. P. Arutyunov, N. A. Bylova, I. I. Dayter, Y. T. F. N. Jao, C. C. Fang, Y. Chen, C. L. Yu, S. P. Wang, J. Valencia, P. Perez-Berbel, J. M. Ruiz-Nodar, J. Pineda, P. Bordes, M. Quintanilla, V. Mainar, F. Sogorb, N. Santos, M. Serrao, H. Cafe, B. Silva, R. Oliveira, G. Caires, A. Drumond, J. Araujo, R. A. Providencia, P. L. Gomes, J. R. Pais, P. Mota, A. M. Leitao-Marques, S. Farhan, R. Jarai, I. Tentzeris, B. Vogel, M. K. Freynhofer, J. Wojta, K. Huber, M. Poli, P. Trambaiolo, F. Corsi, M. De Luca, M. Mustilli, V. Lukic, M. Simonetti, G. Ferraiuolo, M. Lettino, G. Casella, M. R. Conte, L. De Luca, G. Geraci, R. Ceravolo, A. Pani, G. Fradella, A. Schratter, H. Thiele, T. Klemm, K. Demmin, D. Lehmann, M. Mende, G. Schuler, U. Pittl, A. Chernova, S. U. Nikulina, T. Naruke, T. Inomata, T. Yanagisawa, E. Maekawa, T. Mizutani, H. Shinagawa, M. Nishii, I. Takeuchi, H. Takehana, T. Izumi, C. Paulo, J. Mascarenhas, M. Patacho, J. Pimenta, P. Bettencourt, S. Nardai, G. Y. Szabo, B. Berta, I. Edes, B. Merkely, J. Delgado Silva, R. Baptista, R. Faria, J. Trigo, P. Gago, G. Gheorghe, I. T. Nanea, A. Cristea, S. Almarichi, H. Martins, F. Saraiva, E. Jorge, P. L. Mendes, P. Monteiro, S. Costa, F. Franco, L. A. Providencia, T. Nanea, G. S. Gheorghe, S. Visan, N. Paun, R. Gaber, R. Delewi, R. Nijveldt, H. A. De Bruin, A. Hirsch, A. Van Der Laan, B. J. Bouma, J. P. G. Tijssen, A. C. Van Rossum, F. Zijlstra, J. J. Piek, H. Rus, M. Donea, C. Ciurea, G. Ifteni, G. Casolo, M. Chioccioli, M. Magnacca, J. Del Meglio, A. Comella, M. Baratto, J. Lera, L. Salvadori, C. Tessa, C. Vignali, Z. Keca, T. Momcilov Popin, G. Panic, R. White, F. Mateen, A. Weaver, Y. Agmon, E. Okisheva, D. Tsaregorodtsev, V. Sulimov, I. J. Amat Santos, C. Hernandez, C. Tapia, A. Campo, D. Fredman, L. Svensson, M. Rosenqvist, S. Tadel-Kocjancic, P. Radsel, R. Knafelj, V. Gorjup, M. Noc, E. Zima, Z. S. Jenei, E. Kovacs, I. Osztheimer, L. Molnar, A. Horvath, D. Becker, L. Geller, R. Maggi, T. Furukawa, V. Viscardi, M. Brignole, S. R. N. Leal, H. Dores, I. Rosario, J. Monge, M. J. Carvalho, I. Arroja, A. Leitao, C. Fonseca, A. Aleixo, A. Silva, S. Keuleers, P. Herijgers, M. C. Herregods, W. Budts, C. Dubois, B. Meuris, P. Verhamme, W. Flameng, F. Van De Werf, T. Adriaenssens, H. Badran, M. Elnoamany, T. Lolah, C. Olariu, C. Macarie, M. A. H. Mollik, A. I. Hassan, T. K. Paul, M. Z. Haque, R. Jahan, M. Rahmatullah, M. A. Khatun, M. T. Rahman, M. H. Chowdhury, J. Bustamante Munguira, E. Tamayo, I. Garcia-Cuenca, E. Bustamante, J. Gualis, M. L. Gomez-Martinez, S. Florez, J. I. Gomez-Herreras, R. Ramirez Rodriguez, A. M. Ramirez Rodriguez, M. A. Garcia-Bello, E. Hernadez Ortega, E. Caballero Dorta, A. Garcia Quintana, V. Piro Mastraccio, A. Medina Fernandez Aceytuno, E. Assanelli, M. De Metrio, M. Rubino, G. Lauri, A. Cabiati, J. Campodonico, M. Grazi, M. Moltrasio, I. Marana, G. Marenzi, M. Lovlien, B. Schei, R. Picon-Heras, C. Acebal, J. C. Garcia Rubira, D. Vivas Balcones, I. Nunez-Gil, B. Ruiz-Mateos, B. Ibanez, A. Fernandez-Ortiz, V. D. Vintila, O. A. Enescu, C. I. Stoicescu, C. Udroiu, M. Cinteza, G. Tatu - Chitoiu, D. Vinereanu, C. Fresco, M. De Biasio, D. Muser, R. Sappa, G. Morocutti, G. Bernardi, A. Proclemer, B. Fontanella, A. Affatato, C. Ciccarese, M. Sacchini, M. Volpini, F. Bianchetti, G. Verzura, L. Dei Cas, R. Pudil, V. Blaha, J. Vojacek, I. Paraskevaidis, I. Ikonomidis, J. Parissis, C. Papadopoulos, V. Stasinos, V. Bistola, M. Anastasiou-Nana, M. Shochat, A. Shotan, M. Kazatsker, V. Gurovich, A. Asif, E. Noiman, Y. Levy, D. Blondhaim, P. Rabinovich, S. Meisel, S. Petrovic, J. Glasnovic, M. Tomasevic, D. Sakac, S. Obradovic, O. Londono Sanchez, S. Pacreu, L. Torres, G. Mihaylov, G. M. Shaban, E. Trendafilova, V. Krasteva, T. S. Mudrov, J. P. Didon, V. Panageas, N. Vlachos, A. Pernat, I. Radan, H. Mozina, P. Pepi, F. Cionini, N. Baccaglioni, A. Viertel, J. Havers, G. Ballard, G. Groenefeld, L. M. Branco, L. Ferreira, A. Fiarresga, L. Lettieri, A. Reggiani, R. Juarez Prera, G. Blanco Palacios, A.- C. Martin, S. Manzo Silberman, A. Chaib, O. Varenne, P. Allouch, E. Salengro, A. Jegou, O. Margot, C. Spaulding, A. Diego, A. De Miguel, C. Cuellas, E. Fraile, J. Martin, B. Vega, R. Bangueses, F. Fernandez-Vazquez, A. Perez De Prado, S. Leal, M. J. Correia, J. C. Monge, J. Abecasis, C. Garcia-Garcia, I. Subirana, J. Sala, J. Bruguera, V. Valle, G. Sanz, M. Fiol, F. Aros, J. Marrugat, R. Elosua, S. N. C. Barra, A. Leitao Marques, Y. J. Yang, B. Xu, G. Y. Song, R. L. G, A. Aleksic, P. Serpytis, K. Rucinskas, A. Kalinauskas, N. Karvelyte, C. I. Santos De Sousa, S. Ferreira, J. Calaca, N. Lousada, R. Palma Reis, D. M. Gualandro, L. F. B. C. Seguro, F. G. M. Braga, O. M. Silvestre, R. L. Lage, J. Fabri, M. T. Oliveira, J. A. Urbano Moral, J. Torres Llergo, R. Solanilla Rodriguez, A. Sanchez Gonzalez, A. Martinez Martinez, C. A. Den Uil, W. K. Lagrand, M. Van Der Ent, L. S. D. Jewbali, J. M. Cheng, P. E. Spronk, M. L. Simoons, C. Mornos, D. Dragulescu, A. Ionac, J. Guardado, O. Azevedo, M. Fernandes, F. Canario-Almeida, V. Sanfins, A. Pereira, J. Almeida, V. U. Kaplunova, Y. N. Belenkov, E. V. Privalova, A. A. Fomin, A. Y. Suvorov, A. Goodkova, M. G. Rubakova, I. A. Kuznetsova, E. N. Semernin, F. Keshavarzi, J. Kojuri, V. M. Mikhailov, I. V. Vezhenkova, A. Y. A. Goodkova, I. Pavlovic, M. Schwarz, G. Jakl, P. Smetana, T. Perkmann, A. Mayr, J. Mair, G. Klug, M. Schocke, T. Trieb, W. Jaschke, O. Pachinger, B. Metzler, L. Bronze Carvalho, J. Azevedo, M. L. Andrade, M. J. Relvas, J. Coucello, G. Morais, M. 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Unalir, B. Timuralp, N. Nikulina, S. S. Yakushin, G. I. Furmenko, S. A. Akinina, R. Ingrid, L. Bronze, S. Djambazov, A. Zhivkov, I. Maznev, M. Ingeliev, R. Slavov, N. Cvetkova, V. Patarinski, L. Groch, J. Horak, N. Dimitrov, H. G. Hayrapetyan, P. Cabanas-Grandio, C. Pena-Gil, N. A. Mc Keag, C. J. Mc Cann, C. Cardwell, I. S. Young, N. Mikhalchikova, N. Burova, M. Zaccaria, P. Palmisano, V. Palumbo, M. M. Ciccone, S. Favale, K. C. Chen, W. H. Yin, J. H. Liu, S. Goncalves, J. F. Santos, P. Amador, L. N. Soares, K. Zahidova, F. Guliyev, N. Zahidov, P. Carrilho-Ferreira, J. S. Marques, J. Carvalho De Sousa, H. Uthoff, C. Thalhammer, M. Potocki, T. Reichlin, M. Noveanu, M. Aschwanden, D. Staub, N. Arenja, T. Socrates, C. Mueller, Y. Zhao, X. Wu, Q. Xue, L. Gao, H. Lin, S. Wang, K. Watanabe, A. Kawamura, T. Seko, A. Omura, S. Sakabe, A. Kasai, A. V. Starodubova, G. Storozhakov, O. Kisliak, F. Hautieva, M. Tursheva, N. Fedotova, R. C. Di Maio, J. Mclaughlin, J. D. Allen, J. M. C. Anderson, H. Khaled Nagi, O. Tayeh, W. Farok, A. Mousa, P. Neuzil, J. Skoda, J. Petru, L. Sediva, S. Kralovec, F. Holy, K. Holdova, P. Jehlicka, P. Plasil, V. Y. Reddy, S. Alabakovska, D. Labudovic, S. Jovanova, K. Tosheska, M. Alabakovski, K. Jeevaratnam, S. P. Tee, Y. Zhang, L. Guzadhur, I. S. Gurung, R. Duehmke, A. A. Grace, M. Lei, C. L. Huang, Y. Ishibashi, M. Yamauchi, Y. Akashi, H. Musha, F. Miyake, T. Hnatek, L. Kamenik, P. Sedlon, J. Luxova, B. Steuerova, J. Skvaril, M. Cernohous, M. Zavoral, N. Ratkovic, N. R. Nemanja Djenic, A. J. Aleksandra Jovelic, S. O. Slobodan Obradovic, B. G. Branko Gligic, E. Kletsiou, M. Giannakopoulou, E. Bozas, E. K. Iliodromitis, E. D. E. Papathanassoglou, M. Anton, G. Anton, M. Muraru, S. Salinger Martinovic, M. Radosavljevic, D. Stanojevic, M. Zivkovic, T. Pessoa, N. Aspromonte, C. Ronco, M. Tubaro, M. Santini, F. Colivicchi, A. Aiello, D. Cruz, A. Anzoletti Boscolo, G. Vianello, R. Valle, A. Parspour, S. Watkins, D. Datta, A. G. Nikishin, M. M. Pirnazarov, T. A. Nurbaev, Z. Motovska, M. Fischerova, P. Osmancik, M. Maly, P. Widimsky, E. Pavli, A. Dibra, J. Mehilli, L. Dibra, A. Schoemig, A. Kastrati, P. Carmo, M. Almeida, R. Teles, P. Goncalves, J. Brito, F. D'ascenzo, A. Gonella, G. Longo, A. Pullara, C. Moretti, F. Sciuto, P. Omede', G. Biondi Zoccai, G. P. Trevi, I. Sheiban, H. M. Cafe, D. Pereira, D. Freitas, D. Ortiz Berbel, J. M. Rabasa Baraibar, A. M. Leone, A. De Caterina, A. Aurelio, A. Sciahbasi, E. Lioy, C. Trani, F. Burzotta, I. Porto, A. G. Rebuzzi, K. Trusinskis, D. Juhnevica, K. Strenge, D. Sondore, I. Kumsars, S. Jegere, I. Narbute, A. Grave, I. Zakke, A. Erglis, C. Ferrari, A. L. Bartorelli, M. Saeed, D. Cozma, S. Pescariu, S. I. Dragulescu, H. S. Kamal, A. Abdelfattah, A. M. Abdelbary, H. Elassar, A. Naggar, M. Khaled, A. M. Fareed, J. M. Pernes, J. C. Gaux, M. W. Prull, B. Sasko, H. Wirdemann, A. Bittlinsky, T. Butz, H. J. Trappe, M. Perazzolo Marra, L. Cacciavillani, A. Marzari, M. De Lazzari, R. Turri, P. China, F. Corbetti, S. Iliceto, L. L. Stazhadze, E. A. Spiridonova, N. A. Bulanova, A. A. Ermolaev, L. Savic, I. Mrdovic, G. Krljanac, J. Perunicic, M. Asanin, R. Lasica, M. Matic, Z. Vasiljevic, M. Ostojic, M. Tichy, C. Andrys, A. Conti, C. Poggioni, G. Viviani, F. Bulletti, V. Boni, M. Luzzi, S. Vicidomini, M. Donati, B. Del Taglia, R. Pini, O. Sousa, R. Fontes-Carvalho, D. Caeiro, N. Dias Ferreira, G. Silva, E. Pereira, J. Ribeiro, A. Albuquerque, V. Gama Ribeiro, M. Murai, Y. Takeda, T. Shinmyo, J. Tanigawa, H. Hazui, T. Nakakohji, Y. Ohishi, M. Hoshiga, T. Ishihara, T. Hanafusa, J. Belohlavek, V. Rohn, J. Kunstyr, M. Lips, M. Semrad, F. Mlejnsky, J. Tosovsky, A. Linhart, J. Lindner, Z. Sablik, A. Samborska-Sablik, J. Drozdz, W. Gaszynski, M. M. Izquierdo-Gomez, R. Juarez-Prera, G. Blanco-Palacios, R. Lakhdar, M. Drissa, B. Jedaida, H. Drissa, F. Sampaio, H.- T. Hsin, J.- H. Huang, K.- M. Chiu, Z.- S. Chen, P.- C. Lin, L.- Y. Chen, S.- H. Chu, I. Efthimiadis, P. Skendros, A. Sarantopoulos, P. Boura, A. M. Van Der Laan, P. A. Van Der Vleuten, M. Klees, J. G. P. Tijssen, B. E. Backus, A. J. Six, J. H. Kelder, A. Mosterd, E. G. Mast, T. P. Mast, R. Braam, R. Tio, R. Veldkamp, P. A. Doevendans, N. Paarup Dridi, L. Holmvang, T. Engstroem, S. Rekik, J. Brunet, F. X. Hager, G. Bayet, L. Meille, J. M. Quatre, J. Sainsous, P.- H. Chu, C.- H. Tang, N. Pogosova, I. E. Koltunov, I. D. Sapunova, V. A. Vigodin, R. Uhliar, A. Schmidt, B. Brockmeyer, A. Suzuki, Y. Eki, H. Higuchi, A. Yukawa, R. Yamauchi, Y. Sato, Y. Endo, J. Salazar Mendigucha Garcia, S. Homs Vila, A. Cequier Fillat, R. Andion Ogando, M. Sandin Fuentes, J. M. Vegas Valle, I. A. Gonzalez Garcia, I. A. Duro Aguado, A. J. Palomino Doza, I. Gomez Salvador, J. A. San Roman Calvar, T. M. Mamarasulov, L. Todorovic, Z. C. H. Cherneva, S. D. Denchev, K. Heltai, A. Boytsov, N. N. Nikulina, D. Zanna, V. Marangelli, C. Caiati, R. Picon Heras, M. J. Loureiro, I. Urazovskaya, D. Vinogradova, E. Vasilieva, A. Shpektor, E. Conti, M. B. Musumeci, F. M. Lauri, E. Dito, M. De Giusti, A. Lallo, D. Fusco, M. Davoli, M. Volpe, C. Autore, H. Gamra, Z. Dridi, M. Hassine, F. Addad, I. Gherissi, A. Reda, M. Mahjoub, S. Bouraoui, M. Abdennadher, F. Betbout, P. M. F. P. Mota, J. D. Silva, R. Jankovic Tomasevic, V. Djordjevic, D. Djordjevic Radojkovic, A. Scafa Udriste, A. Fruntelata, E. Gainoiu, S. Bogdan, D. Zamfir, C. Teodorescu, M. Guran, D. Constantinescu, A. Konopka, M. Banaszewski, I. Wojtkowska, J. Stepinska, J. V. Vidergold, I. V. Osipova, T. V. Tavrovskaya, J. V. Galkina, A. V. Timofeev, R. I. Vorobyov, E. N. Vorobyova, L. Matos, A. C. C. Carvalho, W. Oliveira, F. Cintra, D. Poyares, M. Andersen, R. Martins, S. Tufik, P. Ostadal, J. Brada, S. Horakova, M. Mlcek, V. Hrachovina, O. Kittnar, I. V. Gorudko, I. V. Buko, S. N. Cherenkevich, L. Z. Polonetsky, V. Y. Plotkin, M. A. Timoshina, S. V. Azanchevskaya, N. N. Chromov-Borisov, A. Vorlat, L. Snoep, M. J. Claeys, C. J. Vrints, A. Palazzuoli, M. Caputo, I. Quatrini, A. Calabro, G. Antonelli, M. S. Campagna, B. Franci, R. Nuti, A. Maisel, M. Negrini, T. Minora, P. Marino, R. Seregni, E. Tavlueva, O. Barbarash, L. Barbarash, T. Janota, J. Kudlicka, K. Malik, D. Wichterle, J. Hradec, R. Body, S. D. Carley, G. Mcdowell, M. Nuttall, C. Wibberley, M. France, J. K. Cruickshank, K. Mackway-Jones, M. Leon, C. Cozma, F. Mitu, D. R. Almeida, C. B. Dias, I. Burazor, M. Burazor, M. Krstic, M. Lazovic, M. Vukmanovic, J. Djordjevic, Z. Radovanovic, D. Ilic, P. Bosnjakovic, A. C. Ferreira, P. S. Mateus, P. Fontes, T. Teixeira, G. Conte, A. Menozzi, E. Solinas, M. G. Bolognesi, I. Tadonio, F. Mantovani, A. Cattabiani, L. Vignali, D. Ardissino, O. Tautu, A. Alexandrescu, R. Niculescu, R. Jankovic, N. Bozinovic, C. Santos, F. Costa, G. Cardoso, I. Correia, K. Fountoulaki, S. Kastellanos, E. Voltirakis, A. Kokotos, C. Michalakeas, K. Kontsas, K. Hasioti, E. T. Iliodromitis, M. G. Sandin Fuentes, E. Zatarain Nicolas, N. Martinez Uruena, M. Alvarado Montes De Oca, V. Dytrych, T. Kovarnik, O. Smid, A. Kral, A. G. Aroutunov, S. Intwala, I. Jegere, H. S. H. Shaalan, Z. Pagava, R. Agladze, R. Shakarishvili, N. Sharashidze, L. Gujejiani, G. Saatashvili, T. Z. Katova, V. Kostova, Y. Simova, S. Vukotic, S. Rafajlovski, R. Romanovic, N. Antonijevic, B. Gligic, M. Hutyra, T. Skala, D. Horak, D. Vindis, M. Taborsky, A. Contine, M. Del Pinto, F. Angeli, P. Verdecchia, F. Borgognoni, E. Grikstaite, P. Pantano, G. Ambrosio, C. Cavallini, C. Bonanad, J. Sanchis, V. Bodi, J. Nunez, X. Bosch, M. Heras, M. Pellicer, A. Llacer, L. Adao, M. Oliveira, H. Goncalves, J. Primo, V. Gama, C. Lombardi, M. Metra, S. Bugatti, E. Pasotti, F. Quinzani, M. Adamo, C. Villa, R. Rovetta, A. Manerba, M. Mariani, A. Dushpanova, M. Baroni, E. Cerone, A. Nardelli, J. Gianetti, S. Berti, F. Feliciano, R. Soares, S. Santos, A. Kruger, D. Vondrakova, J. Herget, C. Navarro, N. A. Cromie, J. A. A. Adgey, D. Caeiro Pereira, P. Braga, R. Fontes Carvalho, A. Rodrigues, M. Goncalves, L. Simoes, and K. V. Borisov

Subjects
Cardiology and Cardiovascular Medicine
Published
2010

36. Influence of BMI, Age and Duration of Diabetes Mellitus on Glycaemic Control with Twice-Daily Injections of Biphasic Insulin Aspart 30 versus Multiple Daily Injections of Insulin Aspart (JDDM 18)

Author

K, Arai, K, Hirao, M, Yamauchi, H, Takagi, M, Kobayashi, and Hiroki, Yokoyama

Subjects
Adult, medicine.medical_specialty, Time Factors, endocrine system diseases, medicine.medical_treatment, Insulin, Isophane, Blood sugar, NPH insulin, Biphasic Insulins, Type 2 diabetes, Body Mass Index, Injections, law.invention, Insulin aspart, Randomized controlled trial, law, Internal medicine, Diabetes mellitus, medicine, Humans, Hypoglycemic Agents, Insulin, Pharmacology (medical), Insulin Aspart, Aged, Retrospective Studies, Glycated Hemoglobin, business.industry, Age Factors, nutritional and metabolic diseases, General Medicine, Middle Aged, medicine.disease, Surgery, Diabetes Mellitus, Type 2, business, medicine.drug
Abstract

Background and Objective: Good glycaemic control in patients with diabetes mellitus often requires insulin supplementation therapy. Recent developments of analogue insulin and premixed formulations have increased the therapeutic options for patients who need such therapy. This study aimed to retrospectively clarify appropriate treatment regimens according to age, body mass index (BMI) and duration of diabetes in Japanese patients with type 2 diabetes previously entered in an open-label, randomized trial that compared convenience-oriented biphasic insulin aspart 30 versus multiple injections of insulin aspart with or without NPH insulin. Methods: Japanese insulin-naive patients were randomized to receive either biphasic insulin aspart 30 twice daily or insulin aspart three times daily with or without multiple injections of NPH insulin for a treatment period lasting 6 months. Results: Reduction of glycosylated haemoglobin (HbA1c) at the end of 6 months was not different in the two treatment groups irrespective of BMI, age and duration of diabetes. However, the achievement rate of HbA1c

Published
2010

37. Radiation dose evaluation in 64-slice CT examinations with adult and paediatric anthropomorphic phantoms

Author

Takahiko Aoyama, Shuji Koyama, Kanae Nishizawa, M Yamauchi, Chiyo Yamauchi-Kawaura, Keiichi Akahane, S. Ko, and Keisuke Fujii

Subjects
Adult, Male, Radiography, Abdominal, medicine.medical_specialty, Tomography Scanners, X-Ray Computed, 64 slice ct, Radiobiology, Radiation Dosage, Effective dose (radiation), Imaging phantom, Pelvis, Humans, Medicine, Dosimetry, Radiology, Nuclear Medicine and imaging, Child, Radiometry, Full Paper, Anthropometry, Phantoms, Imaging, business.industry, Radiation dose, General Medicine, Pelvic cavity, medicine.anatomical_structure, Personal computer, Female, Radiography, Thoracic, Radiology, Tomography, X-Ray Computed, Nuclear medicine, business
Abstract

The objective of this study was to evaluate the organ dose and effective dose to patients undergoing routine adult and paediatric CT examinations with 64-slice CT scanners and to compare the doses with those from 4-, 8- and 16-multislice CT scanners. Patient doses were measured with small (7 mm wide) silicon photodiode dosemeters (34 in total), which were implanted at various tissue and organ positions within adult and 6-year-old child anthropomorphic phantoms. Output signals from photodiode dosemeters were read on a personal computer, from which organ and effective doses were computed. For the adult phantom, organ doses (for organs within the scan range) and effective doses were 8-35 mGy and 7-18 mSv, respectively, for chest CT, and 12-33 mGy and 10-21 mSv, respectively, for abdominopelvic CT. For the paediatric phantom, organ and effective doses were 4-17 mGy and 3-7 mSv, respectively, for chest CT, and 5-14 mGy and 3-9 mSv, respectively, for abdominopelvic CT. Doses to organs at the boundaries of the scan length were higher for 64-slice CT scanners using large beam widths and/or a large pitch because of the larger extent of over-ranging. The CT dose index (CTDI(vol)), dose-length product (DLP) and the effective dose values using 64-slice CT for the adult and paediatric phantoms were the same as those obtained using 4-, 8- and 16-slice CT. Conversion factors of DLP to the effective dose by International Commission on Radiological Protection 103 were 0.024 mSvmGy(-1)cm(-1) and 0.019 mSvmGy(-1)cm(-1) for adult chest and abdominopelvic CT scans, respectively.

Published
2009

38. Dynamic Displacement of Normal and Detached Semicircular Canal Cupula

Author

Stephen M. Highstein, Richard Boyle, Curtis King, Angela M. Yamauchi, Richard D. Rabbitt, and Kathryn D. Breneman

Subjects
Time Factors, Endolymph, Motion Perception, Action Potentials, Article, inner ear micromechanics, Afferent Neurons, Motion, 03 medical and health sciences, 0302 clinical medicine, Physical Stimulation, Afferent, medicine, Animals, Craniocerebral Trauma, Humans, Neurons, Afferent, 030304 developmental biology, Vestibular system, 0303 health sciences, vestibular, cupula regeneration, Semicircular canal, Chemistry, Time constant, Relaxation process, Anatomy, Batrachoidiformes, Adaptation, Physiological, Semicircular Canals, Sensory Systems, angular motion sensation, medicine.anatomical_structure, Otorhinolaryngology, sense organs, afferent response dynamics, Displacement (fluid), 030217 neurology & neurosurgery
Abstract

The dynamic displacement of the semicircular canal cupula and modulation of afferent nerve discharge were measured simultaneously in response to physiological stimuli in vivo. The adaptation time constant(s) of normal cupulae in response to step stimuli averaged 36 s, corresponding to a mechanical lower corner frequency for sinusoidal stimuli of 0.0044 Hz. For stimuli equivalent to 40–200 deg/s of angular head velocity, the displacement gain of the central region of the cupula averaged 53 nm per deg/s. Afferents adapted more rapidly than the cupula, demonstrating the presence of a relaxation process that contributes significantly to the neural representation of angular head motions by the discharge patterns of canal afferent neurons. We also investigated changes in time constants of the cupula and afferents following detachment of the cupula at its apex—mechanical detachment that occurs in response to excessive transcupular endolymph pressure. Detached cupulae exhibited sharply reduced adaptation time constants (300 ms–3 s, n = 3) and can be explained by endolymph flowing rapidly over the apex of the cupula. Partially detached cupulae reattached and normal afferent discharge patterns were recovered 5–7 h following detachment. This regeneration process may have relevance to the recovery of semicircular canal function following head trauma.

Published
2009

39. Study of Ωc0 and Ωc∗0 baryons at Belle

Author

Y. Iwasaki, Y. J. Kwon, Joowon Lee, O. Schneider, T. E. Browder, H. J. Hyun, M. Danilov, L. S. Peak, Vladimir Zhulanov, Y. Miyazaki, M. E. Sevior, A. Zupanc, M. Starič, J. H. Kang, M. Yamauchi, O. Nitoh, S. Eidelman, Vladislav Balagura, P. Pakhlov, D. Liventsev, H. K. Park, J. G. Shiu, Y. Sakai, K. Inami, G. S. Varner, A. Kuzmin, Y. Yamashita, E. Solovieva, Phillip Urquijo, W. S. Hou, H. Kichimi, R. Itoh, K. Arinstein, P. Chang, S. Ogawa, T. Lesiak, P. Wang, Yu. V. Usov, S. Nishida, M. Tanaka, P. Krokovny, O. Zyukova, Masashi Hazumi, X. L. Wang, K. Miyabayashi, S. H. Kyeong, A. Ishikawa, S. K. Choi, S. E. Lee, P. Križan, Y. I. Kim, S. Okuno, M. J. Lee, K. Kinoshita, H. Sahoo, E. Won, B. G. Cheon, M. Bračko, D. Heffernan, T. Uglov, T. Aushev, I. S. Cho, G. N. Taylor, Hirokazu Ishino, Y. Teramoto, Bruce Yabsley, A. M. Bakich, T. Ohshima, K. Senyo, M. Dash, C. H. Wang, U. Bitenc, H. Kawai, A. Bondar, T. Kawasaki, Y. Choi, J. S. Lange, J. Dalseno, I. Tikhomirov, S. Korpar, Jolanta Brodzicka, A. Chen, Yasushi Nagasaka, Samo Stanič, M. Shapkin, Y. J. Kim, Rakesh Kumar, H. Palka, L. E. Piilonen, G. Pakhlova, R. Chistov, T. Sumiyoshi, S. Noguchi, S. Uehara, H. Ha, N. Katayama, R. Mizuk, Y. Unno, I. Adachi, H. Miyata, Y. Hoshi, K. Hayasaka, D. H. Kah, T. Zivko, Y. B. Hsiung, Z. P. Zhang, H. O. Kim, A. Matyja, H. Aihara, C. Liu, M. Nakao, Y. Watanabe, S. McOnie, H. J. Kim, Motoki Iwasaki, S. Uno, and C. Schwanda

Subjects
Nuclear physics, Baryon, Physics, Nuclear and High Energy Physics, Particle physics, KEKB, 010308 nuclear & particles physics, law, 0103 physical sciences, 010306 general physics, Collider, 01 natural sciences, law.invention
Abstract

We report results from a study of the charmed double strange baryons Ωc 0 and Ωc * 0 at Belle. The Ωc 0 is reconstructed using the Ωc 0 → Ω- π+ decay mode, and its mass is measured to be (2693.6 ± 0.3-1.5 +1.8) MeV / c2. The Ωc * 0 baryon is reconstructed in the Ωc 0 γ mode. The mass difference MΩc* 0 - MΩc0 is measured to be (70.7 ± 0.9-0.9 +0.1) MeV / c2. The analysis is performed using 673 fb-1 of data on and near the Υ{hooked} (4 S) collected with the Belle detector at the KEKB asymmetric-energy e+ e- collider. © 2008 Elsevier B.V. All rights reserved.

Published
2009

40. Control of seed borne diseases of rice seedlings by coating seeds with iron

Author

M. Yamauchi, H. Inoue, and H. Miyagawa

Subjects
Agronomy, Biology
Abstract

直播栽培の種子処理技術として開発されてきた鉄コーティング処理について，イネ育苗期に発生する病害に対する防除効果を調査した．苗立枯細菌病，もみ枯細菌病あるいは褐条病を保菌したイネ種子を播種直前に鉄コーティング処理すると，2週間後の病害の発生が抑制されていた．また，ばか苗病，ごま葉枯病，いもち病に対しても，同様に発病抑制が認められた．4種類の鉄粉でコーティングを行ったが，いずれの鉄粉においても，苗立枯細菌病，もみ枯細菌病，褐条病のすべてに防除効果が認められた．以上のことから，イネ種子の鉄コーティング処理は育苗期に発生する病害に抑制効果があり，直播栽培だけでなく移植栽培による箱育苗にも利点があることが明らかとなった．

Published
2009

41. Study of intermediate two-body decays in B¯0→Σc(2455)0p¯π+

Author

A. Ishikawa, C. W. Park, P. Križan, J. H. Kang, Joowon Lee, A. M. Bakich, Z. Natkaniec, T. Ohshima, D. Liventsev, T. Iijima, J. G. Shiu, H. Nakazawa, T. E. Browder, Y. Watanabe, A. Zupanc, J. B. Singh, G. S. Varner, A. Somov, N. Gabyshev, O. Nitoh, M. Tanaka, I. Bedny, Phillip Urquijo, B. Shwartz, R. Itoh, K. Inami, U. Bitenc, D. H. Kah, E. Won, P. Chang, S. W. Lin, M. Nakao, P. Wang, Yu. V. Usov, S. Eidelman, T. Zivko, S. McOnie, M. Z. Wang, Y. Unno, H. J. Kim, D. Heffernan, O. Zyukova, Rakesh Kumar, H. Miyata, A. Kuzmin, I. S. Cho, Y. Hoshi, H. J. Hyun, V.N. Zhilich, G. N. Taylor, D. Epifanov, S. Ogawa, S. Uehara, H. Ha, K. Hayasaka, H. Park, A. Bozek, L. E. Piilonen, N. Katayama, B. G. Cheon, Y. Miyazaki, M. Dash, Masashi Hazumi, Anton Poluektov, S. Okuno, K. S. Park, I. Adachi, V. M. Aulchenko, A. Matyja, C. H. Wang, Vladimir Zhulanov, S. Nishida, H. K. Park, Y. Yamashita, S. Uno, H. Sahoo, Vladislav Balagura, M. E. Sevior, T. Aushev, M. Shapkin, K. Senyo, K. Miyabayashi, X. L. Wang, H. Aihara, V.E. Shebalin, R. Chistov, Samo Stanič, T. Kawasaki, Y. J. Kim, Y. I. Kim, Y. Teramoto, A. Bondar, S. Korpar, T. Sumiyoshi, W. S. Hou, Y. Chao, A. Vinokurova, K. Arinstein, R. Pestotnik, M. Yamauchi, P. Krokovny, H. Kichimi, Z. P. Zhang, Y. Sakai, T. Lesiak, Y. Choi, H. O. Kim, M. J. Lee, J. Dalseno, M. Bračko, Motoki Iwasaki, L. S. Peak, M. Starič, Y. Iwasaki, Y. J. Kwon, O. Schneider, and H. Kawai

Subjects
Physics, Nuclear and High Energy Physics, 010308 nuclear & particles physics, Electron–positron annihilation, Analytical chemistry, Resonance, 01 natural sciences, Baryon, Nuclear physics, KEKB, 0103 physical sciences, B meson, Invariant mass, 010306 general physics
Abstract

We present results of a detailed study of the three-body over(B, )0 → Σc (2455)0 over(p, ) π+ decay. A significant enhancement of signal events is observed in the over(p, ) π+ invariant mass distribution near 1.5 GeV / c2 that is consistent with the presence of an intermediate baryonic resonance over(N, )0, where over(N, )0 is the over(N, ) (1440)0 P11 or over(N, ) (1535)0 S11 state, or an admixture of the two states. We measure the product B (over(B, )0 → Σc (2455)0 over(N, )0) × B (over(N, )0 → over(p, ) π+) = (0.80 ± 0.15 (stat .) ± 0.14 (syst .) ± 0.21) × 10-4, where the last error is due to the uncertainty in B (Λc + → p K- π+). The significance of the signal is 6.1 standard deviations. This analysis is based on a data sample of 357 fb-1, accumulated at the Υ{hooked} (4 S) resonance with the Belle detector at the KEKB asymmetric-energy e+ e- collider. © 2008 Elsevier B.V.

Published
2008

42. New search for τ→μγ and τ→eγ decays at Belle

Author

S. K. Kim, I. Bizjak, H. Miyake, F. Mandl, S. E. Lee, T. Gershon, S. L. Olsen, Z. P. Zhang, K. Hayasaka, O. Nitoh, K. Miyabayashi, J. Brodzicka, A. Chen, H. Hayashii, R. Chistov, T. Lesiak, R. Itoh, T. Matsumoto, C. C. Kuo, S. W. Lin, N. Gabyshev, H. Miyata, P. Krokovny, X. C. Tian, K. Abe, Y. Kozakai, A. Sokolov, Y. Yamashita, C. C. Wang, W. S. Hou, T. Sumiyoshi, A. Kuzmin, L. S. Peak, P. Pakhlov, H. Aihara, D. Liventsev, H. Stoeck, M. E. Sevior, A. Imoto, Y. Teramoto, H. Sahoo, Y. Iwasaki, S. Okuno, N. Soni, I. Tikhomirov, Y. Usov, K. Senyo, G. R. Moloney, A. Bay, T. Schietinger, A.J. Schwartz, J. Haba, J. B. Singh, B. G. Cheon, O. Schneider, Q. L. Xie, S. Hou, S. Stanič, Y. Miyazaki, H. Nakazawa, B. Golob, N. Satoyama, J. H. Kang, H. Ha, A. Ishikawa, K. Arinstein, D. Heffernan, M. Yamauchi, S. Villa, W. T. Chen, T. Hokuue, T. Mori, G. N. Taylor, Y. Chao, K. S. Park, S. Eidelman, M. Nakao, Y. Nagasaka, A. Poluektov, T. Tsukamoto, J. Dalseno, H. Ozaki, E. Barberio, T. Hara, K. Inami, Y. Watanabe, T. Kawasaki, H.K Park, A. Bozek, S. Nishida, K. Tamai, S. Fratina, N. Tamura, M. Hazumi, Z. Natkaniec, P. Križan, A. Go, V. Aulchenko, D. Anipko, K. Belous, A. Yamaguchi, Y. Onuki, S. Uno, Hiroyuki Kaji, M. Starič, T. Uglov, K. Ueno, Y. K. Choi, Y. Sakai, V. Zhulanov, M. Shapkin, R. Kulasiri, H. R. Khan, A. Zupanc, Y. J. Kim, U. Bitenc, L. E. Piilonen, P. Chang, I. Adachi, S. Ogawa, A. Bondar, Masayuki Tanaka, M. C. Chang, Y. Hoshi, A. Drutskoy, Y. J. Kwon, M. Iwasaki, B. D. Yabsley, Y. Choi, C. H. Wang, I. Bedny, S. Uehara, H. Kichimi, F. Takasaki, V. Zhilich, A. Vinokurova, M. Danilov, P. Urquijo, A. Somov, R. Seidl, T. Tsuboyama, D. Epifanov, M. Dash, R. Kumar, T. Iijima, A. M. Bakich, T. Ohshima, G. Varner, K. Ikado, H. Shibuya, B. Shwartz, Kazuhiko Hara, H. Kawai, Michael J. Lee, E. Won, R. Pestotnik, G. Pakhlova, and M. Bračko

Subjects
Nuclear physics, Physics, Nuclear and High Energy Physics, Particle physics, KEKB, Electron–positron annihilation, Lepton number, Belle experiment, Lepton
Abstract

We report on a search for the lepton flavor violating τ−→μ−γ and τ−→e−γ decays based on 535 fb−1 of data accumulated at the Belle experiment. No signal is found and we set 90% confidence level upper limits on the branching ratios B(τ−→μ−γ)

Published
2008

43. Measurement of masses of the Ξc(2645) and Ξc(2815) baryons and observation of Ξc(2980)→Ξc(2645)π

Author

T. Lesiak, I. Adachi, H. Aihara, K. Arinstein, A.M. Bakich, V. Balagura, E. Barberio, I. Bedny, K. Belous, V. Bhardwaj, U. Bitenc, S. Blyth, A. Bozek, M. Bračko, J. Brodzicka, T.E. Browder, Y. Chao, A. Chen, W.T. Chen, B.G. Cheon, R. Chistov, I.-S. Cho, S.-K. Choi, Y. Choi, J. Dalseno, M. Dash, S. Eidelman, N. Gabyshev, B. Golob, H. Ha, J. Haba, K. Hayasaka, M. Hazumi, D. Heffernan, Y. Hoshi, W.-S. Hou, H.J. Hyun, K. Inami, A. Ishikawa, H. Ishino, R. Itoh, M. Iwasaki, Y. Iwasaki, N.J. Joshi, D.H. Kah, H. Kaji, J.H. Kang, H. Kawai, T. Kawasaki, H. Kichimi, H.J. Kim, S.K. Kim, Y.J. Kim, S. Korpar, P. Križan, P. Krokovny, C.C. Kuo, Y.-J. Kwon, S. Lange, J.S. Lee, M.J. Lee, S.E. Lee, J. Li, S.-W. Lin, C. Liu, D. Liventsev, F. Mandl, S. McOnie, T. Medvedeva, K. Miyabayashi, H. Miyake, H. Miyata, Y. Miyazaki, R. Mizuk, G.R. Moloney, Y. Nagasaka, M. Nakao, Z. Natkaniec, S. Nishida, O. Nitoh, T. Nozaki, S. Ogawa, T. Ohshima, S. Okuno, H. Ozaki, G. Pakhlova, H. Palka, C.W. Park, H.K. Park, L.S. Peak, R. Pestotnik, L.E. Piilonen, H. Sahoo, Y. Sakai, O. Schneider, K. Senyo, M.E. Sevior, M. Shapkin, H. Shibuya, J.-G. Shiu, B. Shwartz, A. Sokolov, S. Stanič, M. Starič, T. Sumiyoshi, F. Takasaki, M. Tanaka, G.N. Taylor, Y. Teramoto, I. Tikhomirov, K. Trabelsi, T. Tsuboyama, S. Uehara, K. Ueno, T. Uglov, Y. Unno, S. Uno, P. Urquijo, G. Varner, K.E. Varvell, K. Vervink, C.C. Wang, C.H. Wang, M.-Z. Wang, P. Wang, X.L. Wang, Y. Watanabe, R. Wedd, E. Won, B.D. Yabsley, H. Yamamoto, Y. Yamashita, M. Yamauchi, Z.P. Zhang, V. Zhilich, V. Zhulanov, A. Zupanc, and O. Zyukova

Subjects
Physics, Baryon, Nuclear and High Energy Physics, Particle physics, KEKB, 010308 nuclear & particles physics, 0103 physical sciences, Pi, 010306 general physics, 01 natural sciences
Abstract

We report a precise measurement of the masses of the $\Xi_c(2645)$ and $\Xi_c(2815)$ baryons using a data sample of 414 fb$^{-1}$ collected by the Belle collaboration at the KEKB $e^+ e^-$ collider. The states $\Xi_c(2645)^{0,+}$ are observed in the $\Xi_c^{+,0}\pi^{-,+}$ decay modes, while the $\Xi_c(2815)^{0,+}$ are reconstructed in the $\Xi_c(2645)^{+,0}\pi^{-,+}$ decay modes. The following mass splittings are determined: $m_{\Xi_c(2645)^+} - m_{\Xi_c(2645)^0} = (-0.1 \pm 0.3 ({\rm stat}) \pm 0.6 {(\rm syst})) {\rm MeV}/{\rm c}^2$ and $m_{\Xi_c(2815)^+} - m_{\Xi_c(2815)^0} = (-3.4 \pm 1.9 ({\rm stat}) \pm 0.9 {(\rm syst})) {\rm MeV}/{\rm c}^2$ with a much better precision than the current world averages. We also observe a new decay mode, $\Xi_c(2980)^{0,+} \to \Xi_c(2645)^{+,0}\pi^{-,+}$.

Published
2008

44. Mars Express and Venus Express multi-point observations of geoeffective solar flare events in December 2006

Author

Hans Nilsson, Andrew J. Coates, Stas Barabash, Yoshifumi Futaana, P. Riihela, R. A. Frahm, A. Fedorov, J. R. Sharber, Wolfgang Baumjohann, K. C. Hsieh, Eduard Dubinin, K. Brinkfeldt, J. D. Winningham, Esa Kallio, A. Grigoriev, M. Maggi, S. M. P. McKenna-Lawlor, Kazushi Asamura, J. J. Thocaven, Christian Mazelle, David Brain, R. Cerulli-Irelli, Markus Fränz, M. Yamauchi, J. A. Sauvaud, Janet G. Luhmann, Peter Wurz, Alessandro Mura, Pontus Brandt, T. Sales, T. L. Zhang, Ella Carlsson, Anna Milillo, D. O. Kataria, J. R. Scherrer, J. Woch, Walter Schmidt, Bill R. Sandel, C. C. Curtis, P. Bochsler, Mats Holmström, S. Orsini, J. Kozyra, Rickard Lundin, Herbert Gunell, N. Krupp, Karoly Szego, D. R. Linder, Hannu Koskinen, H. Andersson, Helmut Lammer, Manuel Grande, and E. Roelof

Subjects
Space weather, 010504 meteorology & atmospheric sciences, Proton, Mars, Venus, 01 natural sciences, law.invention, law, 0103 physical sciences, Coronal mass ejection, 010303 astronomy & astrophysics, 0105 earth and related environmental sciences, Physics, Solar flare, biology, Astronomy, Astronomy and Astrophysics, Mars Exploration Program, biology.organism_classification, SEP, 13. Climate action, Space and Planetary Science, Heliospheric current sheet, Ion escape, Flare
Abstract

In December 2006, a single active region produced a series of proton solar flares, with X-ray class up to the X9.0 level, starting on 5 December 2006 at 10:35 UT. A feature of this X9.0 flare is that associated MeV particles were observed at Venus and Mars by Venus Express (VEX) and Mars Express (MEX), which were ∼80° and ∼125° east of the flare site, respectively, in addition to the Earth, which was ∼79° west of the flare site. On December 5, 2006, the plasma instruments ASPERA-3 and ASPERA-4 on board MEX and VEX detected a large enhancement in their respective background count levels. This is a typical signature of solar energetic particle (SEP) events, i.e., intensive MeV particle fluxes. The timings of these enhancements were consistent with the estimated field-aligned travel time of particles associated with the X9.0 flare that followed the Parker spiral to reach Venus and Mars. Coronal mass ejection (CME) signatures that might be related to the proton flare were twice identified at Venus within

Published
2008

45. Ionospheric photoelectrons at Venus: Initial observations by ASPERA-4 ELS

Author

David Brain, R. Cerulli-Irelli, Hannu Koskinen, N. Krupp, M. Yamauchi, A. Grigoriev, Peter Wurz, D. R. Linder, J. Woch, P. Bochsler, Y. Soobiah, Manuel Grande, S. M. P. McKenna-Lawlor, Stas Barabash, Karoly Szego, Wolfgang Baumjohann, A. Fedorov, Michael W. Liemohn, Mats Holmström, M. Maggi, Pontus Brandt, Glyn Collinson, C. C. Curtis, Herbert Gunell, Markus Fraenz, R. A. Frahm, J. D. Winningham, Esa Kallio, Rickard Lundin, J. J. Thocaven, E. Roelof, Eduard Dubinin, H. Andersson, Yibo Ma, T. L. Zhang, J. A. Sauvaud, D. O. Kataria, Andrew J. Coates, J. Kozyra, S. Orsini, Anna Milillo, A. Asamura, S. J. Jeffers, Bill R. Sandel, Alessandro Mura, André Galli, Yoshifumi Futaana, J. R. Sharber, and K. C. Hsieh

Subjects
Electron spectrometer, 010504 meteorology & atmospheric sciences, chemistry.chemical_element, Venus, lonosphere, 01 natural sciences, 7. Clean energy, Ion, Atmosphere of Venus, Plasma, Ionization, 0103 physical sciences, Physics::Atomic and Molecular Clusters, Physics::Atomic Physics, 010303 astronomy & astrophysics, Helium, 0105 earth and related environmental sciences, Physics, biology, Astronomy and Astrophysics, Photoelectric effect, biology.organism_classification, chemistry, 13. Climate action, Space and Planetary Science, Physics::Space Physics, Astrophysics::Earth and Planetary Astrophysics, Ionosphere, Atomic physics
Abstract

We report the detection of electrons due to photo-ionization of atomic oxygen and carbon dioxide in the Venus atmosphere by solar helium 30.4 nm photons. The detection was by the Analyzer of Space Plasma and Energetic Atoms (ASPERA-4) Electron Spectrometer (ELS) on the Venus Express (VEx) European Space Agency (ESA) mission. Characteristic peaks in energy for such photoelectrons have been predicted by Venus atmosphere/ionosphere models. The ELS energy resolution (ΔE/E~7%) means that these are the first detailed measurements of such electrons. Considerations of ion production and transport in the atmosphere of Venus suggest that the observed photoelectron peaks are due primarily to ionization of atomic oxygen

Published
2008

46. The Venusian induced magnetosphere: A case study of plasma and magnetic field measurements on the Venus Express mission

Author

Peter Wurz, Pekka Janhunen, A. Fedorov, Alessandro Mura, T. Sales, Stas Barabash, S. Orsini, M. Yamauchi, S. M. P. McKenna-Lawlor, Yoshifumi Futaana, Karoly Szego, Mats Holmström, R. A. Frahm, J. R. Sharber, H. Andersson, E. Roelof, I. Sillanpää, Janet G. Luhmann, Hannu Koskinen, D. O. Kataria, Bill R. Sandel, Christian Mazelle, T. L. Zhang, Rickard Lundin, J. D. Winningham, Wolfgang Baumjohann, J. A. Sauvaud, P. Bochsler, M. Maggi, Helmut Lammer, Anna Milillo, N. Krupp, Herbert Gunell, D. R. Linder, J. R. Scherrer, Pontus Brandt, Andrew J. Coates, P. Riihela, Walter Schmidt, J. Kozyra, C. C. Curtis, K. C. Hsieh, J. J. Thocaven, Manuel Grande, Christopher T. Russell, R. Cerulli-Irelli, Esa Kallio, J. Woch, Kazushi Asamura, Riku Jarvinen, A. Grigoriev, and K. Brinkfeldt

Subjects
010504 meteorology & atmospheric sciences, Solar wind, Magnetosphere, Planetary magnetospheres, 01 natural sciences, Venus?solar wind interaction, Magnetosheath, 0103 physical sciences, Interplanetary magnetic field, Mercury's magnetic field, 010303 astronomy & astrophysics, 0105 earth and related environmental sciences, Physics, Astronomy and Astrophysics, Dipole model of the Earth's magnetic field, Geophysics, Bow shocks in astrophysics, Venus, Computational physics, 13. Climate action, Space and Planetary Science, Numerical modelling, Physics::Space Physics, Magnetopause, Astrophysics::Earth and Planetary Astrophysics
Abstract

Plasma and magnetic field measurements made onboard the Venus Express on June 1, 2006, are analyzed and compared with predictions of a global model. It is shown that in the orbit studied, the plasma and magnetic field observations obtained near the North Pole under solar minimum conditions were qualitatively and, in many cases also, quantitatively in agreement with the general picture obtained using a global numerical quasi-neutral hybrid model of the solar wind interaction (HYB-Venus). In instances where the orbit of Venus Express crossed a boundary referred to as the magnetic pileup boundary (MPB), field line tracing supports the suggestion that the MPB separates the region that is magnetically connected to the fluctuating magnetosheath field from a region that is magnetically connected to the induced magnetotail lobes.

Published
2008

47. Study of the decay mechanism for B+→pp¯K+ and B+→pp¯π+

Author

S. Okuno, T. Iijima, L. E. Piilonen, T. Aushev, V. M. Aulchenko, G. Pakhlova, E. L. Barberio, M. Z. Wang, K. Kinoshita, Y. Teramoto, G. N. Taylor, S. Nishida, I. Tikhomirov, A. Chen, Samo Stanič, Y. Iwasaki, M. Shapkin, Robin Wedd, Y. J. Kim, H. Ozaki, Y. J. Kwon, M. Yamauchi, A. M. Bakich, T. Ohshima, E. Nakano, O. Schneider, H. J. Hyun, A. Kuzmin, C. C. Chiang, P. Chang, K. Senyo, M. Nakao, K. Ueno, Joowon Lee, Y. Unno, Andrey Sokolov, T. Kawasaki, V.N. Zhilich, C. C. Zhang, A. Yamaguchi, N. Gabyshev, H. Hayashii, S. W. Lin, R. Pestotnik, S. McOnie, T. E. Browder, S. Ogawa, H. Shibuya, H. Miyake, W. A. Mitaroff, J. H. Kang, A. Somov, R. Seidl, Y. Miyazaki, K. F. Chen, Young-Il Choi, D. Liventsev, K. Miyabayashi, S. Uehara, M. Danilov, C. C. Kuo, S. Uno, Y. Chao, I. S. Cho, G. S. Varner, T. Hokuue, S. Eidelman, P. Pakhlov, R. Mizuk, H. Ha, A. Ishikawa, A. Bay, N. Katayama, R. Itoh, S. E. Lee, S. Fratina, F. Takasaki, M. Starič, Rakesh Kumar, P. Wang, C. W. Park, P. Križan, K. Inami, H. Park, A. Bozek, F. Mandl, I. Adachi, Y. Sakai, Z. P. Zhang, C. H. Wang, U. Bitenc, Y. Yamashita, K. Tamai, S. Villa, K. Ikado, Masashi Hazumi, T. Matsumoto, T. Sumiyoshi, M. Bračko, Yu-xi Liu, H. Sahoo, M. E. Sevior, T. Uglov, Kevin Varvell, Osamu Tajima, A. Matyja, A. Zupanc, O. Nitoh, H. Aihara, Y. Choi, T. Hara, M. Tanaka, X. C. Tian, B. G. Cheon, J. Haba, A. Bondar, K. Belous, S. Korpar, D. Heffernan, E. Won, J. G. Shiu, Phillip Urquijo, M. Dash, B. Golob, S. Cole, H. Kichimi, T. Tsuboyama, T. Lesiak, K. Vervink, H. Kawai, Y. Watanabe, A. Vinokurova, Motoki Iwasaki, P. Krokovny, Yasushi Nagasaka, K. S. Park, Vladislav Balagura, S. L. Olsen, H. Miyata, Y. Hoshi, Tatiana Medvedeva, J. Schümann, K. Hayasaka, J. T. Wei, D. H. Kah, Y. B. Hsiung, J. B. Singh, A. Drutskoy, and C. C. Wang

Subjects
Physics, Nuclear and High Energy Physics, Near threshold, KEKB, Electron–positron annihilation, Analytical chemistry, Pi, High Energy Physics::Experiment, Atomic physics, Helicity
Abstract

We study the characteristics of the low mass p (p) over bar enhancements near threshold in the three-body decays B+ -> p (p) over barK(+) and B+ -> p (p) over bar pi(+). We observe that the proton polar angle distributions in the p (p) over bar helicity frame in the two decays have the opposite polarity, and measure the forward-backward asymmetries as a function of the p mass for the p (p) over barK(+) mode. We also search for the intermediate two-body decays, B+ -> (p) over bar Delta(++) and B+ -> p (Delta) over bar (0), and set upper limits on their branching fractions. These results are obtained from a 414 fb(-1) data sample that contains 449 x 10(6) B (B) over bar events collected near the Gamma(4S) resonance with the Belle detector at the KEKB asymmetric-energy e(+)e(-) collider. (c) 2007 Elsevier B.V. All rights reserved.

Published
2008

48. Comparative analysis of Venus and Mars magnetotails

Author

A. Fedorov, E. Roelof, Hannu Koskinen, J. Woch, K. Brinkfeldt, J. J. Thocaven, Andrew J. Coates, N. Krupp, Helmut Lammer, Bill R. Sandel, M. Maggi, Janet G. Luhmann, D. R. Linder, Stas Barabash, Yoshifumi Futaana, Esa Kallio, Manuel Grande, J. R. Sharber, Wolfgang Baumjohann, Peter Wurz, S. M. P. McKenna-Lawlor, P. Riihela, J. D. Winningham, Christopher T. Russell, Mats Holmström, J. Kozyra, Alessandro Mura, Anna Milillo, J. R. Scherrer, Pontus Brandt, K. C. Hsieh, T. Sales, A. Grigoriev, Christian Mazelle, C. C. Curtis, J. A. Sauvaud, Rickard Lundin, Kazushi Asamura, Tielong Zhang, S. Orsini, M. Yamauchi, Walter Schmidt, H. Andersson, Karoly Szego, P. Bochsler, C. Ferrier, Herbert Gunell, R. Cerulli-Irelli, D. O. Kataria, and R. A. Frahm

Subjects
010504 meteorology & atmospheric sciences, Magnetosphere, Mars, Venus, 01 natural sciences, Current sheet, Magnetosheath, Physics::Plasma Physics, Planet, 0103 physical sciences, 010303 astronomy & astrophysics, 0105 earth and related environmental sciences, Physics, biology, Plasma sheet, Astronomy, Astronomy and Astrophysics, Plasma, Mars Exploration Program, biology.organism_classification, Space and Planetary Science, Physics::Space Physics, Astrophysics::Earth and Planetary Astrophysics, Magnetotail
Abstract

We have an unique opportunity to compare the magnetospheres of two non-magnetic planets as Mars and Venus with identical instrument sets Aspera-3 and Aspera-4 on board of the Mars Express and Venus Express missions. We have performed both statistical and case studies of properties of the magnetosheath ion flows and the flows of planetary ions behind both planets. We have shown that the general morphology of both magnetotails is generally identical. In both cases the energy of the light ( H + ) and the heavy ( O + , etc.) ions decreases from the tail periphery (several keV) down to few eV in the tail center. At the same time the wake center of both planets is occupied by plasma sheet coincident with the current sheet of the tail. Both plasma sheets are filled by accelerated (500–1000 eV) heavy planetary ions. We report also the discovery of a new feature never observed before in the tails of non-magnetic planets: the plasma sheet is enveloped by consecutive layers of He + and H + with decreasing energies.

Published
2008

49. First observation of energetic neutral atoms in the Venus environment

Author

Wolfgang Baumjohann, Janet G. Luhmann, Andrei Fedorov, P. Riihela, Bill R. Sandel, Dhiren Kataria, K. C. Hsieh, Karoly Szego, André Galli, K. Brinkfeldt, Pontus Brandt, Janet U. Kozyra, S. M. P. McKenna-Lawlor, C. C. Curtis, Christopher T. Russell, D. R. Linder, Esa Kallio, Stas Barabash, Markus Fraenz, J. R. Scherrer, R. A. Frahm, J. A. Sauvaud, Edmond C. Roelof, H. Koskinen, R. Cerulli-Irelli, Joachim Woch, T. L. Zhang, Andrew J. Coates, Herbert Gunell, A. Grigoriev, Alessandro Mura, Christian Mazelle, Anna Milillo, Stefano Orsini, M. Maggi, Norbert Krupp, Yoshifumi Futaana, Manuel Grande, H. Andersson, J. R. Sharber, Helmut Lammer, J. J. Thocaven, Mats Holmström, Peter Wurz, D. Winningham, Kazushi Asamura, Walter Schmidt, Rickard Lundin, M. Yamauchi, Peter Bochsler, and T. Sales

Subjects
Physics, 010504 meteorology & atmospheric sciences, Energetic neutral atom, Spacecraft, biology, business.industry, Astronomy, Solar wind-planetary atmosphere interaction, Astronomy and Astrophysics, Venus, Plasma, Mars Exploration Program, biology.organism_classification, 01 natural sciences, Atmosphere of Venus, 13. Climate action, Space and Planetary Science, 0103 physical sciences, ENAs, Venus exosphere, business, Neutral particle, 010303 astronomy & astrophysics, 0105 earth and related environmental sciences, Exosphere
Abstract

The ASPERA-4 instrument on board the Venus Express spacecraft offers for the first time the possibility to directly measure the emission of energetic neutral atoms (ENAs) in the vicinity of Venus. When the spacecraft is inside the Venus shadow a distinct signal of hydrogen ENAs usually is detected. It is observed as a narrow tailward stream, coming from the dayside exosphere around the Sun direction. The intensity of the signal reaches several 10 5 cm - 2 sr - 1 s - 1 , which is consistent with present theories of the plasma and neutral particle distributions around Venus.

Published
2008

50. The Combination of High Glucose and Advanced Glycation End-products (AGEs) Inhibits the Mineralization of Osteoblastic MC3T3-E1 Cells through Glucose-induced Increase in the Receptor for AGEs

Author

M. Yamamoto, Toshitsugu Sugimoto, Toru Yamaguchi, S. Yano, M. Yamauchi, and Noriko Ogawa

Subjects
Glycation End Products, Advanced, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Osteocalcin, Receptor for Advanced Glycation End Products, Clinical Biochemistry, Biochemistry, Bone resorption, Cell Line, Mice, Calcification, Physiologic, Endocrinology, Glycation, Internal medicine, medicine, Animals, Mannitol, RNA, Messenger, Receptors, Immunologic, Receptor, Von Kossa stain, Osteoblasts, biology, Chemistry, Biochemistry (medical), Osteoblast, General Medicine, Glucose, medicine.anatomical_structure, Gene Expression Regulation, Cell culture, biology.protein, medicine.drug
Abstract

Type 1 diabetes mellitus is known to be associated with reduced bone mass and increased bone fractures. This is thought to be due to a decrease in osteoblastic bone formation rather than an increase in osteoclastic bone resorption, but the precise mechanism is unknown. In this study, we examined whether or not high glucose or advanced glycation end-products (AGEs), which play key roles in the pathogenesis and complications of diabetes, affect the differentiation of osteoblastic MC3T3-E1 cells. First, MC3T3-E1 cells were incubated in media containing either 22 mM glucose, 22 mM mannitol, 300 microg/ml AGE2, or 300 microg/ml AGE3. Each of these agents alone did not affect the mineralization of the cells by von Kossa staining and Alizarin red staining. However, high glucose but not mannitol or AGEs markedly increased mRNA expression of AGE receptor (RAGE) by real-time PCR. Next, we examined the combined effects of high glucose and AGEs on the differentiation of MC3T3-E1 cells. The combination of 22 mM glucose and 300 microg/ml AGE2 significantly inhibited the mineralization of MC3T3-E1 cells, and 22 mM glucose in combination with either 300 microg/ml AGE2 or AGE3 apparently decreased osteocalcin mRNA expression. These results suggest that high glucose or AGEs alone might have no effect on osteoblastic differentiation, but their combination could additionally or synergistically inhibit osteoblastic mineralization through glucose-induced increase in RAGE expression.

Published
2007

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