245,098 results on '"Lopes, A."'
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2. High-resolution multi-scale air pollution system: Evaluation of modelling performance and emission control strategies
- Author
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Diogo Lopes, Joana Ferreira, Sandra Rafael, Ka In Hoi, Xin Li, Yuan Liu, Ka-Veng Yuen, Kai Meng Mok, and Ana Isabel Miranda
- Subjects
Environmental Engineering ,Environmental Chemistry ,General Medicine ,General Environmental Science - Published
- 2024
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3. ALTERAÇÕES FUNCIONAIS E COGNITIVAS EM PACIENTES PÓS-COVID 19: UMA REVISÃO INTEGRATIVA
- Author
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Gabriel Vitor Lopes da Silva
- Published
- 2024
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4. Effects of hospital facilities on patient outcomes after cancer surgery
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Knight, Sr, Chu, K, Lapitan, Mc, Dare, Aj, Pius, R, Shaw, Ca, Drake, Tm, Norman, L, Ademuyiwa, Ao, Adisa, Ao, Aguilera, Ml, Al-Saqqa, Sw, Al-Slaibi, I, Bhangu, A, Biccard, Bm, Brocklehurst, P, Costas-Chavarri, A, Elhadi, M, Fairfield, Cj, Fitzgerald, Je, Ghosh, D, Glasbey, J, Henegouwen, Miv, Ingabire, Jca, Kingham, Tp, Lawani, I, Lieske, B, Lilford, R, Martin, J, Mclean, Ka, Moore, R, Morton, D, Nepogodiev, D, Ntirenganya, F, Pata, F, Pinkney, T, Stephen, R Knight, Catherine, A Shaw, Riinu, Pius, Thomas, M Drake, Lisa, Norman, Adesoji, O Ademuyiwa, Adewale, O Adisa, Maria Lorena Aguilera, Sara, W Al-Saqqa, Ibrahim, Al-Slaibi, Aneel, Bhangu, Bruce, M Biccard, Peter, Brocklehurst, Ainhoa, Costas-Chavarri, Kathryn, Chu, Anna, Dare, Muhammed, Elhadi, Cameron, J Fairfield, J Edward Fitzgerald, Dhruv, Ghosh, James, Glasbey, Mark, I van Berge Henegouwen, C Allen Ingabire, J, T Peter Kingham, Marie Carmela Lapitan, Ismaïl, Lawani, Bettina, Lieske, Richard, Lilford, Janet, Martin, Kenneth, A McLean, Rachel, Moore, Dion, Morton, Dmitri, Nepogodiev, Faustin, Ntirenganya, Francesco, Pata, Thomas, Pinkney, Ahmad Uzair Qureshi, Antonio Ramos-De la Medina, Aya, Riad, Hosni Khairy Salem, Joana, Simões, Richard, Spence, Neil, Smart, Stephen, Tabiri, Hannah, Thomas, Thomas, G Weiser, Malcolm, West, John, Whitaker, Ewen, M Harrison, Arben, Gjata, Maria Marta Modolo, Sebastian, King, Erick, Chan, Sayeda Nazmun Nahar, Ade, Waterman, Dominique, Vervoort, Alemayehu Ginbo Bedada, Bernardo De Azevedo, Ana Gabriela Figueiredo, Manol, Sokolov, Venerand, Barendegere, Gerald, Ekwen, Arnav, Agarwal, Qinyang, Liu, Juan Camilo Correa, Kalisya Luc Malemo, Jacques, Bake, Jakov, Mihanovic, Kamila, Kunčarová, Julius, Orhalmi, Hosni, Salem, Jyri, Teras, Aristotelis, Kechagias, Alexis, P Arnaud, Judith, Lindert, Vasileios, Kalles, Maria-Lorena, Aguilera-Arevalo, Gustavo, Recinos, Zsolt, Baranyai, Basant, Kumar, Harish Neelamraju Lakshmi, Sanoop Koshy Zachariah, Philip, Alexander, Sunil Kumar Venkatappa, Pramesh, C, Radhian, Amandito, Christina, Fleming, Luca, Ansaloni, Gianluca, Pellino, Ahmed, M Altibi, Ibrahim, Nour, Intisar, Hamdun, Ali, M Ghellai, Donatas, Venskutonis, Tomas, Poskus, Justas, Zilinskas, Precious, Malemia, Yong Yong Tew, Elaine, Borg, Sarah, Ellul, Fatima Zahraa Wafqui, David, W Borowski, Anne Sophie van Dalen, Cameron, Wells, Harissou, Adamou, Adesoji, Ademuyiwa, Adewale, Adisa, Kjetil, Søreide, Sara Al Saqqa, Osaid, Alser, Haya, Tahboub, Helmut Alfredo Segovia Lohse, Sebastian Shu Yip, Piotr, Major, António Sampaio Soares, Matei Razvan Bratu, Andrey, Litvin, Armen, Vardanyan, Ahmad, Gudal, Naif, Albati, Jovan, Juloski, Miran, Rems, Sarah, Rayne, Stephanie Van Straten, Yoshan, Moodley, Irene Ortega Vázquez, Jaime, Ruiz-Tovar, Kithsiri Janakantha Senanayake, Sujeewa Priyantha Bandara Thalgaspitiya, Omer Abdelbagi Omer, Anmar, Homeida, Yucel, Cengiz, Daniel, Clerc, Muhammad, Alshaar, Hanen, Bouaziz, Yuksel, Altinel, Matthew, Doe, Maryna, Freigofer, Ella, 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Damir, Jemendžić, Branislav, Kocman, Oliver, Šuman, Renata, Canic, Darko, Jurišić, Ivana, Karakas, Ana Krizanovic Rupcic, Vlatka, Pitlovic, Josip, Samardžić, Mario, Kopljar, Ivan, Bacic, Edgar, Domini, Robert, Karlo, Danijela, Miljanić, Andrea, Simic, Mariam, Ahmed, Majdi Al Nassrallah, Rabiya, Altaf, Talal, Amjad, Ruba, Eltoum, Heba, Haidar, Alhassan, Hassan, Omar, Khalil, Marwan, Qasem, Rommel, Ramesh, Gautham, Sajith, Maham, Wisal, Jan, Žatecký, Michele, Bujda, Katerina, Jirankova, Ales, Paclik, Aya, Abdallah, Mariam Abdulgawad Almogy, Esraa Ayman El-Sawy, Ahmed Moustafa ElFayoumy, Nourhan, Elghareeb, Nourhan Ahmed Esmat, Ahmed, Fadel, Abdullah, Habater, Heba, Hamdy, Amr, Hefni, Marwa, Kamal, Norhan Mohamed Abobakr, Ahmed, Sayed, Nancy, Shaker, Ehab, Taha, Hoda, Tharwat, Omar, Zakaria, Ibrahem, Abdelmotaleb, Ali, Al-Dhufri, Hamza, S Al-Himyari, Enas El Sheikh, Asmaa, Eldmaty, Aya, Elkhalawy, Ahmed, M Elkhashen, Kithara, Magdy, Safa, Mostafa, Habib Doutoum Sadia, Mohamed Mahmoud Saleh, Dina, Samir, Mohamed Yahia Mohamed Ali, Mahmoud, A Nassar, Samar, Abdelhady, Aly, Abdelrazek, Israa, Abdelsalam, Aya, El-Sawy, Eman, Essam, Mohamed, Gadelkarim, Khaled, Ghaly, Mohamed, Hassabalnaby, Rana, Masarani, Nourhan Mohamed Shaaban, Ahmed, Sabry, Menatalla, Salem, Nourhan Akram Soliman, Diaaaldin, Zahran, Moustafa Ramadan Abou El Soud, Esraa Tarek Badr, Hala, Borham, Nehal, Elmeslemany, Mohammad, Elsayed, Fawzia, Elsherif, Sara, Eslam, Gehad, Gaber, Sondos, Ibrahim, Yara, Kamh, Abdelrahman, Mahmoud, Shimaa Gamal Mohamed, Eman, Morshedy, Cinderella, Omar, Fatima Salem Soliman, Shaza, Abdelkawy, Naglaa, Abdelmohsen, Mahmoud, Abdelshakour, Ahmed, Dahy, Norhan, Gamal, Mohammed, Gamal, Ahmad, Hasan, Helal, Hetta, Nehad, Mousa, Mohamed, Omar, Somia, Rabie, Mahmoud, Saad, Bakeer, Saleh, Marwa Sayed Mohamed, Muhammad, Shawqi, Heba Abdelhady Mousa, Mostafa, Alnoury, Mohamed, Elbealawy, Ahmed, Elshafey, Muhammad Essam Ibrahim El Desouki Muhammad Ahmed, Mennatullah, Ghonaim, Fawzy, 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Taqwa, Sayed, Tarneem, Shehada, Ahmed Mohy Zidan, Khalid, Abbas, Amr, Ali, Mohamed, Attia, Mohamed, Balata, Ayman El Nakeeb, Mohamed Ibrahim Elsayed Elewaily, Ahmed, Elfallal, Hossam, Elfeki, Ahmed, Elkhadragy, Sameh, Emile, Helmy, Ezzat, Hasnaa, Hosni, Islam, Mansour, Waleed, Omar, Gehad, Othman, Kareem, Sadek, Mostafa, Shalaby, Noura, Shehab-Eldeen, Rawda Anas Khalifa, Helmy, Badr, Mostafa, Eldeep, Ahmed, Eldeep, Amany Eldoseuky Mohammed, Salwa, Khallaf, Eman Magdy Hegazy, Rokia, Mahmoud, Pola, Mikhail, Mahmoud, Morsi, Sara, Mowafy, Dina, Raafat, Amina, Safy, Marwa, Sera, Ahmed Shible Sera, Mostafa Salim Mohamed AbdAllah, Muhammad, Abdelkader, Abdulrahman Osama Abdou, Ahmedgaber, Ahmed, Shireen, Gaafar, Fatma Ibrahim Negm, Mina, Lapic, Ahmed, Maher, Hagar, Mahmoud, Ahmed, Mostafa, Mohamed, Samir, Fatma, Samy, Nourhan, Semeda, Hind, I Shalaby, Alaa, El-Taweel, Ahmed Galal Elnagar, Ahmed Gamal Hemidan, Mohamed, Hussein, Ahmed, A Kandil, Moawad, Mf, Ayat Allah Nasser Hamamah, Mostafa, Soliman, Mohamed, Abdelkhalek, Noura Abdelmaksoud Tawakel, Ahmed Mohamed Abdelwahed, Alrawy, Abdou, Khalid, Atallah, Mohammed Yasser Elsherbeny, Eman, Emara, Mohamed, Hamdy, Omar, Hamdy, Amira, Haron, Salma, Ismail, Islam Hany Metwally, Nihal Mohamed Hamed Elgaml, Ahmed, Nassar, Basel, Refky, Mirna, Sadek, Mahmoud, Saleh, Asmaa, Yunes, Mai, Zakaria, Mohammed, Zuhdy, Notila, Fayed, Mohammed Mustafa Hassan Mohammed, Sander, Kütner, Priit, Melnik, Indrek, Seire, Toomas, Ümarik, Eppu, Ainoa, Verner, Eerola, Hanna, Koppatz, Laura, Koskenvuo, Ville, Sallinen, Sini, Takala, Jevgeni, Katunin, Arto, Turunen, Niki, Christou, Muriel, Mathonnet, Vincent, Lavoue, Krystel Nyangoh Timoh, Lucie, Soulabaille, Romain, Lesourd, Aude, Merdrignac, Laurent, Sulpice, Benoît, André, Elodie, Chantalat, Charlotte, Vaysse, Bertrand, Dousset, Sebastien, Gaujoux, Gregory, Martin, Octavian, Clonda, Domantas, Juodis, Klaus, Kienle, Andras, Mravik, Samuel, Palmer, Gabor, Szabadhegyi, Anita Eseenam Agbeko, Solomon, Gyabaah, Frank Enoch Gyamfi, Nuhu, Naabo, Atta Owusu Senior, Joseph, Yorke, Frank, Owusu, Francis, Abantanga, Theophilus Teddy Kojo Anyomih, Abdul-Jalilu Mohammed Muntaka, Emmanuel Owusu Abem, Mohammed, Sheriff, Paul, M Wondoh, Dimitrios, Balalis, Dimitrios, Korkolis, Georgios, Gkiokas, Eirini, Pantiora, Theodosios, Theodosopoulos, Argyrios, Ioannidis, Konstantinos, Konstantinidis, Sofia, Konstantinidou, Nikolaos, Machairas, Anna, Paspala, Anastasia, Prodromidou, Christos, Chouliaras, Konstantinos, Papadopoulos, Ioannis, Baloyiannis, Ioannis, Mamaloudis, George, Tzovaras, Ioanna, Akrida, Maria-Ioanna, Argentou, Stylianos, Germanos, Evangelos, Iliopoulos, Ioannis, Maroulis, George, Skroubis, George, Theofanis, Christos, Chatzakis, Orestis, Ioannidis, Lydia, Loutzidou, Panagiotis, Karathanasis, Nikolaos, Michalopoulos, Charalampos, Theodoropoulos, Dimitrios, Theodorou, Tania, Triantafyllou, Zoe, Garoufalia, Natasha, Hasemaki, Michalis, Kontos, Gregory, Kouraklis, Stylianos, Kykalos, Theodore, Liakakos, Eustratia, Mpaili, Alexandros, Papalampros, Dimitrios, Schizas, Athanasios, Syllaios, Ekaterini Christina Tampaki, Antonios, Tsimpoukelis, Maria Ioanna Antonopoulou, Eirini, Deskou, Dimitrios, K Manatakis, Dimitrios, Papageorgiou, Menelaos, Zoulamoglou, Christos, Anthoulakis, Michalis, Margaritis, Nikolaos, Nikoloudis, Veronica, Campo, André, Ceballos, Mario-Andrés, Flores, Waleska, Giron, Donghyun, Ko, Gabriel, Martinez, Verónica Rivera Lara, Nataly, Rueda, Andres, Sanchez, Jorge Carlos Guillermo Tejeda Garrido, Alvaro Eduardo Alvarez Rivera, Elvis Benjamin Bamaca Ixcajoc, Lilian Elizabeth Barreda Zelaya, Patricia, Chacòn-Herrera, Ligia Margarita Corea Ruiz, Guillermo, Echeverria-Davila, Mario, Garcia, Danilo, García, Edgar Fernando Gutiérrez Mayen, Noriega, José, Nery, Mazariegos, Diego, Méndez, Michael Paniagua Espinoza, David, Bardos, Marton, Benke, Kristof, Illes, Balint András Kokas, Réka, Szabó, Akhila, Appukuttan, Anjitha, Asok, D K, Vijaykumar, Kapil, Malik, Praveen, Ravishankaran, Ritesh, Tapkire, Guru, Moorthy, Joyner, Abraham, Ramesh, Muthuvel, John, Alapatt, Abhay, Kattepur, Nizamudheen, Pareekutty, Mebanshanbor, Garod, Caleb, Harris, Cliff, Wanniang, Ashish, Gupta, Deepak, Nehra, Sanjeev, Parshad, Rajgopal, Acharya, Rajendra, Badwe, Manish, Bhandare, Urvashi, Jain, Karishma, Kirti, Nita, Nair, Shailesh, Shrikhande, Purvi, Thakkar, Premkumar, Anandan, C S, Archana, Arun Holenarasipur Narasannaiah, Tejaswi, Jagarlamudi, M R, Rashmi, Mallikarjuna, Manangi, Abhishek, Raghavendra, K Seshagiri Rao, Vinay, S, Vinay, Sajjan, Aneesh, Shenoy, Santhosh Shivashankar Chikkanayakanahalli, Kavya, Tharanath, Sushmita, V, Peter, Adidharma, Raksheeth, Agarwal, Phebe Anggita Gultom, Ghafur Rasyid Arifin, Matthew, Billy, Zatira, Elfizri, Alessa, Fahira, Devi, Felicia, Triana Hardianti Gunardi, Nadya, Johanna, Nadia Rahmadiani Nugrahadi, Sonar Soni Panigoro, Siti, Rahmayanti, Retta Catherina Sihotang, Santi Yuanita Brata, Hadi, Winoto, Nastaran, Barati, Manoochehr, Karami, Hamidreza, Khorshidi, Homa, Naderifar, Mazin, A Abdulla, Maggie, Coleman, Ronan, J Doherty, Rob, Hannon, Brenda, Murphy, Aine, Stakelum, Des, Winter, Lylas, Aljohmani, Richard, Farnan, Yeshey, Seldon, Tanna, Tan, Shriya, Varghese, Mohammad, Alherz, Muaaz, Ather, Mohammad, Bajilan, Vivien, Graziadei, Isobel, Pilkington, Omar, Quidwai, Paul, Ridgway, Haaris, Shiwani, Abd Al-Rahman Tahir, Eimear, Blunnie, Daniel, Burke, Niall, Kennedy, Kate, Macdonagh, Maeve, O'Neill, Siobhan, Rooney, Giuseppe, Falco, Guglielmo, Ferrari, Simone, Mele, Gabriela Elisa Nita, Lara, Ugoletti, Maurizio, Zizzo, Gianmaria, Confalonieri, Giovanni, Pesenti, Fulvio, Tagliabue, Gianluca, Baronio, Deborah, Ongaro, Giacomo, Pata, Bruno, Compagnoni, Renato, Salvadori, Lucio, Taglietti, Nicola, D'Alessandro, Pierpaolo Di Lascio, Giovanni, Pascale, Luca, Bortolasi, Tommaso, Campagnaro, Massimo, Carlini, Giorgio, Lisi, Davide, Lombardi, Corrado, Pedrazzani, Domenico, Spoletini, Giulia, Turri, Paola, Violi, Donato Francesco Altomare, Fabrizio, Aquilino, Nicola, Musa, Vincenzo, Papagni, Arcangelo, Picciariello, Leonardo, Vincenti, Dario, Andreotti, Savino, Occhionorelli, Matteo, Tondo, Stefano Maria Massimiliano Basso, Paolo, Ubiali, Riccardo, Cirelli, Marco Enrico Mario Maino, Guglielmo Niccolò Piozzi, Emanuele, Picone, Rosa, Scaramuzzo, Giovanni, Sinibaldi, Alfonso, Amendola, Lorenzo, Anastasio, Luigi, Bucci, Emanuele, Caruso, Antonio, Castaldi, Sara Di Maso, Vincenza Paola Dinuzzi, Giovanni, Esposito, Maria, Gaudiello, Mariano Cesare Giglio, Paola Antonella Greco, Gaetano, Luglio, Andrea, Manfreda, Ester, Marra, Federica, Mastella, Gianluca, Pagano, Roberto, Peltrini, Vincenzo, Pepe, Michele, Sacco, Viviana, Sollazzo, Giovanni, Spiezio, Ettore, Cianchetti, Nunzia, Menduni, Michele Maria Carvello, Francesca Di Candido, Antonino, Spinelli, Fabio, Corsi, Luca, Sorrentino, Fabio, Marino, Emanuele Luigi Giuseppe Asti, Luigi, Bonavina, Emanuele, Rausa, Martina, Asta, Andrea, Belli, Francesco, Bianco, Carmela, Cervone, Paolo, Delrio, Armando, Falato, Andrea Fares Bucci, Rita, Guarino, Ugo, Pace, Daniela, Rega, Emilia De Luca, Gaetano, Gallo, Giuseppe, Sammarco, Giuseppe, Sena, Giuseppina, Vescio, Letizia, Santandrea, Giampaolo, Ugolini, Davide, Zattoni, Nicola, Chetta, Gaetano, Logrieco, Serafino, Vanella, Gianluca, Garulli, Nicola, Zanini, Andrea, Bondurri, Francesco, Cammarata, Francesco, Colombo, Diego, Foschi, Giulia Maria Beatrice Lamperti, Anna, Maffioli, Gianluca Matteo Sampietro, Al'Ona, Yakushkina, Gloria, Zaffaroni, Enrico, Cicuttin, Maria Grazia Sibilla, Harmony, Impellizzeri, Marco, Inama, Gianluigi, Moretto, Sylvie, Mochet, Elisa, Ponte, Antonella, Usai, Stefano, Mancini, Andrea, Sagnotta, Luigi, Solinas, Elisa, Bolzonaro, Nicolò, Tamini, Gianluca, Curletti, Raffaele, Galleano, Michele, Malerba, Sofia, Campanella, Gianfranco, Cocorullo, Francesco, Colli, Paolino De Marco, Nicolò, Falco, Tommaso, Fontana, Leonel Jospin Kamdem Mambou, Antonella La Brocca, Leo, Licari, Brenda, Randisi, Giovanna, Rizzo, Giulia, Rotolo, Giuseppe, Salamone, Roberta, Tutino, Paolina, Venturelli, Stefano, Malabarba, Alessandro, Sgrò, Ivan, Vella, Bruno, Cirillo, Daniele, Crocetti, Giorgio De Toma, Pierfrancesco, Lapolla, Andrea, Mingoli, Paolo, Sapienza, Angela, Belvedere, Stefania, Bianchini, Margherita, Binetti, Arianna, Birindelli, Valeria, Tonini, Mauro, Podda, Fabio, Pulighe, Michele De Rosa, Lorenzo, Bono, Felice, Borghi, Paolo, Geretto, Maria Carmela Giuffrida, Corrado, Lauro, Alessandra, Marano, Luca, Pellegrino, Paola, Salusso, Diego, Sasia, Michela, Campanelli, Alberto Realis Luc, Mario, Trompetto, Roberto, Cardia, Nicola, Cillara, Antonio Nicola Giordano, Antonio, Costanzo, Mario Alessandro Giovilli, Luca, Turati, Silvestro, Canonico, Sciaudone, Guido, Francesco, Selvaggi, Lucio, Selvaggi, Nader, Albsoul, Ahmad, Albsoul, Ala'a Aldeen Alkhatib, Osama, Alsallaq, Justin, Z Amarin, Rami, Ayoub, Isam, Bsisu, S El Muhtaseb, M, Mohammad, Jabaiti, Jamal, Melhem, Yasmeen, Z Qwaider, Mohammad Hasan Salameh, Ahmad, Suleihat, Haya, H Suradi, Mohammad, Alammarin, Almoutuz, Aljaafreh, Mohammad Bani Hani, Zeina Bani Hani, Farah Bani Hani, Toqa, Fahmawee, Shadi, Hamouri, Cyrine, Katanani, Ra'Fat, Tawalbeh, Tamara, Tawalbeh, Hassan, Zawahrah, Mohamad, K Abou Chaar, Lana, Abusalem, Mahmoud, Al-Masri, Hani, Al-Najjar, Lutfi, Barghuthi, Zahra, Ahmed, Adnan, Maulana, Omar, Ngotho, Charbel, Kamau, Aruyaru Stanley Mwenda, Fridah, Bosire, Elizabeth, Mwachiro, Robert, Parker, Ian, Simel, Kimutai, Sylvester, Abdulmunem Ahmed Mustafa Althini, Sofian, Elbarouni, Aya Elseed Elbeshina, Ahmed, Gwea, Ans, Malek, Wedad Albashir Masoud Farag, Abdulwahab, Abdalei, Abu Baker Abdel Malik, Areej, Abo-Khammash, Ma'Aly, Abuhlaiga, Nour, Adnan, Marwa, Albaggar, Asma, Alfitory, Asma, Aljanfi, Fakhruddin, Almuzghi, Zohoor, Altumei, Fatima, Alzabti, Hana, Ashoushan, Mohamed, Assalhi, Joma, Azzubia, Sondos, Bnhameida, Malik, Delhen, Houssein, Elshafei, 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Alcides Ylatoma Díaz, Mark Anthony Fontanilla, Joseph Roy Fuentes, Anna Leah Salazar, Genieve, Dominguez, Marc Paul Lopez, Shiela, Macalindong, Mark Augustine Onglao, Arjel, Ramirez, Marie Dione Sacdalan, Mayou Martin Tampo, Gemma Leonora Uy, Jeremiah, Mangahas, Kenneth, Yabut, Joannes Paul Cañete, Bernalynn Eris Cansana, Ernes John Castro, Maria Kaiserin Lipana, Manuel Francisco Roxas, Vlu Jean Zara, Maciej, Chroł, Paula, Franczak, Michał, Orłowski, Piotr, Budzyński, Andrzej, Budzyński, Pawel, Bury, Agata, Czerwińska, Jadwiga, Dworak, Jacek, Dziedzic, Michał, Kisielewski, Jan, Kulawik, Anna, Lasek, Piotr, Małczak, Marcin, Migaczewski, Michał, Pędziwiatr, Magdalena, Pisarska, Dorota, Radkowiak, Mateusz, Rubinkiewicz, Anna, Rzepa, Tomasz, Skoczylas, Maciej, Stanek, Katarzyna, Truszkiewicz, Mateusz, Wierdak, Marek, Winiarski, Piotr, Zarzycki, Anna, Zub-Pokrowiecka, Piotr, Kowalewski, Rafał, Roszkowski, Maciej, Walędziak, Miguel, Tomé, Sara, Patrocinio, Ines, Guerreiro, Filipe, Almeida, 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Macedo Alves, Rita, Peixoto, Catarina, Quintela, Maria João Jervis, Débora, Melo, André, Pacheco, Valter, Paixão, Vera, Pedro, Joana, Pimenta, João Pimenta de Castro, Ana, Rocha, Mircea, Beuran, Cezar, Ciubotaru, Bogdan, Diaconescu, Sorin, Hostiuc, Ionut, Negoi, Bogdan, Stoica, Evgeny, Anokhin, Georgy, Kuznetsov, Giorgi, Oganezov, Fedor, Paramzin, Ekaterina, Romanova, Valeryan, Rutkovskii, Vasilii, Rutkovskii, Mikhail, Shushval, Mikhail, Zabiyaka, Khasan, Dzhumabaev, Valerii, Ivanov, Zaman, Mamedli, Sergey, Achkasov, Artem, Balkarov, Elnur, Nabiev, Marat, Nagudov, Evgeny, Rybakov, Karina, Saifutdinova, Oleg, Sushkov, Lule, Joseph, Isaac, Ndayishimiye, Ntirenganya, Faustin, Alphonse Zeta Mutabazi, Jean Paul Mvukiyehe, Vizir J, P Nsengimana, Carine, Uwakunda, Mohammad Monir Abbas, Nouf, Akeel, Murad, Aljiffry, Kholoud, Awaji, Ali, Farsi, Ghader, Jamjoum, Ahmad, Khoja, Ashraf, Maghrabi, Nadim, Malibary, Mohammed, Nassif, Abdulaziz, Saleem, Abdullah, Sultan, Wail, Tashkandi, Hanaa, 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M., Martin-Borregon, P., Martinez Caballero, J., Nevado Garcia, C., Rodriguez Fraga, P., De Castro Parga, G., Fernandez Veiga, M. P., Garrido Lopez, L., Infante Pino, H., Lages Cal, I., Lopez Otero, M., Nogueira Sixto, M., Paniagua Garcia Senorans, M., Rodriguez Fernandez, L., Ruano Poblador, A., Rufo Crespo, E., Sanchez-Santos, R., Vigorita, V., Alonso Batanero, E., Asnel, D., Cifrian Canales, I., Contreras Saiz, E., De Santiago Alvarez, I., Diaz Vico, T., Fernandez Arias, S., Fernandez Martinez, D., Garcia Bernardo, C., Garcia Florez, L. J., Garcia Gutierrez, C., Garcia Munar, M., Marquez Zorrilla Molina, C. A., Merayo, M., Michi Campos, J. L., Moreno Gijon, M., Otero-Diez, J. L., Rodicio Miravalles, J. L., Solar-Garcia, L., Suarez Sanchez, A., Truan, N., Alejandre Villalobos, C., Caballero Diaz, Y., Jimenez, M., Montesdeoca, D., Navarro-Sanchez, A., Vega, V., Beltran de Heredia, J., Gomez, Z., Jezieniecki, C., Legido Moran, A. P., Montes-Manrique, M., Rodriguez-Lopez, M., Ruiz Soriano, M., Trujillo Diaz, J., Vazquez Fernandez, A., Argudo, N., Pera, M., Torrent Jansa, L., Garcia Dominguez, M., Goded, I., Roldon Golet, M., Talal El-Abur, I., Utrilla Fornals, A., Zambrana Campos, V., Aguilar Martinez, M. D. M., Bosch, M., Garcia-Catala, L., Sanchez-Guillen, L., Artigau, E., Gomez Romeu, N., Julia Bergkvist, D., Espina Perez, B., Morato, O., Olona, C., Dieguez, B., Forero-Torres, A., Losada, M., Gomez-Abril, S., Gonzalvez, P., Martinez, R., Navarro Martinez, S., Paya-Llorente, C., Perez Rubio, A., Santarrufina Martinez, S., Sebastian Tomas, J. C., Trullenque Juan, R., Gegundez Simon, A., Mate, P., Prieto-Nieto, M. I., Rubio-Perez, I., Urbieta, A., Vicario Bravo, M., Abello, D., Frasson, M., Garcia-Granero, A., Abad Gurumeta, A., Abad-Motos, A., Lucena-de Pablo, E., Nozal, B., Ripolles-Melchor, J., Salvachua, R., Ferrero, E., Garcia-Sancho Tellez, L., Picardo, A. L., Rojo Lopez, J. A., Zorrilla Matilla, L. P., Cagigas Fernandez, C., Castanedo Bezanilla, S., Estevez Tesouro, J., Fernandez-Diaz, M. J., Garcia Cardo, J., Gomez Ruiz, M., Gonzalez-Tolaretxipi, E., Jimeno Fraile, J., Poch, C., Rodriguez-Aguirre, M., Troche Pesqueira, N., Trugeda-Carrera, M. S., de la Torre, J., Blanco-Colino, R., Espin-Basany, E., Espinosa-Bravo, M., Morales Comas, C., Reyes Afonso, E., Rivero Deniz, J., Siso Raber, C., Verdaguer Tremolosa, M., Chandrasinghe, P., Kumarage, S., Wijekoon Arachchilage, N., Abdalla Ahmed Elkamel, A., A. Adam, M., Blomme, N., Thorell, A., Wogensen, F., Alga, A., Ansarei, D., Celebioglu, F., Heinius, G., Nigard, L., Pieniowski, E., Ahlqvist, S., Bjorklund, I., Franberg, A., Hakansson, M., Adamo, K., Franklin, O., Sund, M., Wiberg, R., Andersson, Y., Chabok, A., Nikberg, M., Kugelberg, A., Canonica, C., Christoforidis, D., Fasolini, F., Gaffuri, P., Giuliani, M., Meani, F., Popeskou, S. G., Pozza, S., Wandschneider, W., Peterer, L., Widmer, L. W., Zimmermann, B., Bakoleas, P., Chanousi, I., Charalampidou, L., Grochola, L. F., Heid, F., Ntaoulas, S., Outos, M., Peros, G., Podolska-Skoczek, H., Reinisch, K. B., Zielasek, C., Demartines, N., Gilgien, J., Kefleyesus, A., St-Amour, P., Toussaint, A., Alhimyar, M., Alsaid, B., Alyafi, A., Alkhaledi, A., Kouz, B., Omarain, A., Al-Sabbagh, Y., Alkhatib, H., Sara, S., Alhaj, A., Danial, A., Kadoura, L., Maa Albared, S., Monawar, Y., Nahas, L., Abd, B., Saad, A., Wakkaf, H., Bouzaiene, H., Ghalleb, M., Akaydin, E., Akbaba, A. C., Atakul, O., Baltaci, E., Besli, S., Burgu, G., Cenal, U., de Muijnck, C., Demirkaya, H. C., Dogruoz, A., Gezer, Z. I., Gundogdu, Y., Kara, M., Korkmaz, H. K., Kurtoglu, G. K., Ozben, V., Ozmen, B. B., Pektas, A. M., Sel, E. K., Yenidunya, N., Bengur, F. B., Oral, B. M., Yozgatli, T. K., Abdullayev, S., Gunes, M. E., Sahbaz, N. A., Banaz, T., Kargici, K., Kuyumcu, O. F., Yanikoglu, E., Yesilsancak, M., Yilmaz, D., Aktas, M. K., Rencuzogullari, A., Isik, A., Leventoglu, S., Yalcinkaya, A., Yuksel, O., Kalayci, M. U., Kara, Y., Sarici, I. S., Akin, A., Alemdag, G. N., Arslan, E., Baki, B. E., Bodur, M. S., Calik, A., Candas Altinbas, B., Cihanyurdu, I., Erkul, O., Gul, B., Guner, A., Kose, B., Semiz, A., Sevim, Tayar, S., Tomas, K., Tufek, O. Y., Turkyilmaz, S., Ulusahin, M., Usta, A., Yildirim, R., Guler, S. A., Tatar, O. C., Varol, E., Kirimtay, B., Uysal, M., Yildiz, A., Kose, E., Ciftci, A. B., Colak, E., Eraslan, H., Kucuk, G. O., Yemez, K., Lule, H., Bienfait, M., Bua, E., Okalany, N., Basarab, M., Bielosludtsev, O., Kolhanova, K., Perepelytsia, K., Romanukha, K., Savenkov, D., Siryi, S., Tereshchenko, M., Viacheslav, N., Volovetskyi, A., Kebkalo, A., Tryliskyy, Y., Tyselskiy, V., Bruce, E., Chow, B. L., Iddles, E., Mcguckin, S., Newall, N., Ramsay, G., Sharma, P., Stewart, C., Wong, J., Badran, A., Bath, M., Belais, F., Butt, E., Joshi, K., Kapur, M., Shaw, M., Townson, A., Williams, C. Y. K., Gray, T., Greig, R., Husain, M., Murray, E., Mustafa, A., Asif, A., Gokul, A., Shah, M., Akitikori, M. T., Charalabopoulos, A., Davidson, S., Mcnally, S., Rupani, S., Juma, F., Mills, S. C., Muirhead, L., Sellars, K., Walsh, U., Warren, O., Chambers, A., Hunt, R., Boyce, S., Cornwall, H., Tol, I., Argyriou, E. O., Eardley, N., Povey, M., Aithie, J. M. S., Irfan, A., Mcguigan, M. -C., Starr, R., Warren, C. R., Archibald, J., Kirby, G., Kisyov, I., Khoo, C. K., Lee, R., Photiou, D., Davis, R., Prasad, U., Yang, P. Z., Bird, J., Leung, E., Summerour, V., Currow, C., Kiam, J., Tan, G. J. S., Muthusami, A., Pegba-Otemolu, I., Urbonas, T., Nunoo-Mensah, J., Smolskas, E., Boddy, A., Gravante, G., Hunter, D., Andrew, D., Koh, A., Thompson, A., Adams, L., Clements, H. A., De Silva, K., Ekpete, O., Haque, S., Henderson, S., Ibrahim, B., Jayasinghe, T., Livie, J., Mailley, K., Nair, G., Tan, D., Baggaley, C., Dawidziuk, A., Szyszka, B., Barter, C., Gandhi, N., Hassell, K., Hitchin, S., Kelsall, J., Nagy, E., Nessa, A., Whisker, L., Yanni, F., Ali, M., Arora, D., Hediwattege, S., Kumarasinghe, N., Rathore, M., Tennakoon, A., Ali Ahmad, S. M., Bajomo, O., Nadira, F., Celentano, V., Griffiths, E., Karri, R. S., Mak, J. K. C., Pipe, M., Bhatti, M. I., Rabie, M., Boyle, C., Hamilton, D., Mihuna, A., Ng, J. C. K., Nicholson, G., Oliwa, A., Pearson, R., Rose, A., Yong, S. Q., Boereboom, C., Hanna, M., Walter, C., Greensmith, T. S., Mitchell, R., Monaghan, E., Crawford, J., Moug, S., Blackwell, J., Boyd-Carson, H., Herrod, P., Al-Allaf, O., Beattie, M., Bullock, C., Burman, S., Clark, G., Flamey, N., Flannery, O., Harding, A., Kodiatt, B., Lawday, S., Mahapatra, S., Mukundu Nagesh, N., Ng, M., Rye, D., Yoong, A., Clark, L., Deans, C., Edirisooriya, M., Carrington, E. V., Wong, T. L. E., Yusuf, B., Chamberlain, C., Duke, K., Kmiotek, E., Botes, A., Condie, N., Schrire, T., Shah, R., Thomas-Jones, I., Yates, C., Anthony, N., Matthews, E., Sahnan, K., Tankel, J., Tucker, S., Winter Beatty, J., Ziprin, P., Duggan, W., Kantartzi, A., Sridhar, S., Khaw, R. A., Srivastava, P., Underwood, C., Alves do Canto Brum, H., Chopra, S., Davis, L., Hughes, R., Tulley, J., Alberts, J., Athisayaraj, T., Olugbemi, M., Ahmad, K., Chan, C., Chapman, G., Fleming, H., Fox, B., Grewar, J., Hulse, K., Rutherford, D., Sinead, M., Speake, D., Vaughan-Shaw, P. G., Christodoulides, N., Kudhail, S., Welch, M., Husaini, S. M., Lambracos, S., Anyanwu, C., Suresh, R., Thomas, J. S., Gleeson, E., Platoff, R., Saif, A., Enumah, Z., Etchill, E., Gabre-Kidan, A., Bernstein, M., Carrano, F. M., Connors, J., Lynn, P., Melis, M., Newman, E., Foster, D. S., Perrone, K., Titan, A., Ahmad, S., Bafford, A. C. M. D., Dal Molin, M., Hanna, N., Zafar, S. N., Hemmila, M., Napolitano, L., Wong, J. J., Chandler, J., Wood, L., Wren, S., Ottesen, T., You, L., Yu, K., Arcienega Yanez, M. D. P., Ferreira Fernandes, M., Gonzalez, D., Cubas, S., Gonzalez, M. C., Zubiaurre, V., Demolin, R., Giroff, N., Sciuto, P., Campos, M., Rodriguez Cantera, G., Deepika, G., Simuchimba, E., Bulaya, A., Chibuye, C., Chirengendure, B., Kabale, M. -R., Kabongo, K., Munthali, J., Mweso, O., Pikiti, F., Otieno, J., Lai, L. T., Blackman, B., Subramaniam, S., Karim, R., Kok, N., Lee, Y. D., Ali, S., Sinha, A., Corrigan, R., Barnes, N., Wong, F., Dennis, G., Jedamzik, J., Phillips, E., Piette, W., Van hentenryck, M., Koco, H., Lawani, S., Kassa, M. W., Santos Bezerra, T., Gribnev, P., Dimitrov, D., Krastev, P., Oum, S., Bonghaseh, D. T., Al Farsi, M., Alsharqawi, N., Acevedo, V., Castillo Barbosa, A. C., Giron, F., Leon Rodriguez, J. P., Kucan, D., Rosko, D., Barsic, N., Zupan, D., Hegazi, A., Truncikova, V., Fryba, V., Mohamed, M., Nagi, A., Rashad Temerik, A., Elshawy, M. E., Mahmoud, M. I., Anwar, M., Rageh, T., Elmokadem, A., Gaballa, K., Teppo, S., Pengerma, P., Ballouhey, Q., Bergeat, D., Weyl, A., Hain, E., Gyedu, A., Yenli, E., Osei-Poku, D., Rompou, V. -A., Zoikas, A., Gaitanidis, A., Koukis, G., Perivoliotis, K., Tavlas, P., Galanos-Demiris, K., Zografos, G., Karavokyros, I., Xanthopoulou, G., Iordanidou, E., Ayau, F., Garcia, A., Damjan, P., Wason, D., B L, A., Rangganata, E., Kamath, P., O'Connor, D. B., Pinto, M., Perrone, F., Tropeano, F. P., Troilo, F., Bossi, D., Scala, D., Pulitano, L., Carella, M., Pietrabissa, A., Gori, A., Giraudo, G., De Simone, V., Russo, A. A., Braccio, B., Al-Taher, R., Athamneh, S., Parker, A., Sawiee, A., Kattia, A., Tababa, O., Shaeeb, Z., Syminas, V., Jurgaitis, J., Damuleviciene, G., Svagzdys, S., Razafimanjato, N. N. M., Chieng Loo, L., Tiong, I. C., Wan Muhmad, W. F., Vijeyan, H., Li Ying, T., Grech, G., Arrangoiz, R., Jimenez Ley, V. B., Arizpe, D., Lagunes Lara, E., Castro Lopez, E. V., Eaazim, J., Gordinou de Gouberville, M., Bastiaenen, V., Rottier, S., Nahab, F., Ji, M. Y., Seyoji, M., Nwachukwu, C., Emeghara, O., Muhammed, S. E., Idowu, A., Sowemimo, O., Ogundoyin, O., Akande, O., Lott, A., Nadeem, M., Laghari, A. A., Loya, A., Mushtaq, H., Abdullah, M. T., Abuhilal, B., Atawneh, M., Hamdan, H., Alhabil, B., Srour, A., Mousa, I., Da Silva Medina, L., Bartosiak, K., Ferreira, P., Francisco, V., Lemos, R., Frutuoso, L., Fernandes, S., Fonseca, T., Pereira, J., Rachadell, J., Torre, A., Madeira Martins, F., Carvalho, A. C., Rodrigues Ferreira, J., Ribeiro da Silva, B., Devesa, H., Vieira, A., Monica, I., Amaro, M., Sousa, D., Reia, M., Louro, J., Martins, A., Dominguez, J., Santos, I., Freitas Oliveira, N. M., Pereira, J. C., Silva-Vaz, P., Freire, L., Escrevente, R., Negoita, V. M., Shakhmatov, D., Nezerwa, Y., Radulovic, R., Obery, G., Viljoen, F., Mendes, T., Suarez, A., Moncada, E., Fernandez-Hevia, M., Curtis Martinez, C., Gil Garcia, J. M., Gonzalez Zunzarren, M., Idris, T., Eklov, K., Grahn, O., Amin, L., Blomqvist, M., Ajani, C., Kraus, R., Seeger, N., Willemin, M., Rayya, F., Ayash, M., Msouti, R., Kannas, I., Abazid, E., Esper, A., Slim, S., Kavcar, A. S., Aytac, E., Dural, A. C., Ilker, A., Eray, I. C., Kurnaz, E., Altiner, S., Tepe, M. D., Sahin, C., Savli, E., Innocent, A., Babirye, L., Diachenko, A., Hordoskiy, V., Curry, H., Chau, C. Y. C., Robertson, H., Lennon, H., Loi, L., Kirkham, E., Mccann, C., Watts, D., Gurung, B., Wilson, M., Tribedi, T., Garofalo, E., Zahra, B., Macdonald, S., Daniels, I., Ng, N., Khosla, S., Olivier, J., Yue, S. Y. P., Suresh, G., Wellington, J., Lorejo, E., Mossaad, M., Crutcher, M., Alimi, M., Baiu, I., Abdou, H., Conway, A., Peck, C., Perdomo Perez, M. A., Zulu, S., Nakazwe, M., Burger, S., Davies, J., Donaldson, R., Ede, C., Garden, O. J., Lesetedi, C., Mabedi, C., Magill, L., Makinde Alakaloko, F., Makupe, A., Monahan, M., Mulira, S., Muller, E., Musowoyo, J., Olory-Togbe, J. L., Roberts, T., Smith, M., Tayler, V., Windsor, J., Yepez, R., Sundar, S., Runigamugabo, E., Verjee, A., Chen, J., Daya, L., El Aroussi, N., Farina, V., Gnintedeme Olivier, T., Gonzales Nacarino, M., Hammani, A., Honjo, S., Jacobs, R., Kimura, H., Nkoronko, M., Oscullo Yepez, J. J., Pin Hung, W., Raj, A., Romani Pozo, A., Rommaneh, M., Sassamela Fabiano, S. C., Shiroma Gago, C. M., Srinivas, A., Sung, C. -Y., Tai, A., Valle Aranda, Y. C., Venturini, S., Wilguens Lartigue, J., Public and occupational health, AMS - Sports, APH - Health Behaviors & Chronic Diseases, CCA - Cancer Treatment and quality of life, Amsterdam Gastroenterology Endocrinology Metabolism, Cancer Center Amsterdam, and Albarella, Sara
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global surgery ,hospitals ,humans ,income ,neoplasms ,postoperative period ,poverty ,prospective studies ,no keywords listed ,General Medicine ,Prospective Studie ,Hospital ,Settore MED/18 - Chirurgia Generale ,outcome ,Hospitals, Humans, Income, Neoplasms, surgery, Postoperative Period, Poverty, Prospective Studies ,cancer surgery ,Human ,hospital facilities - Abstract
© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide. Methods: A multimethods analysis was performed as part of the GlobalSurg 3 study—a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital. Findings: Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3·85 [95% CI 2·58–5·75]; p
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- 2022
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5. Bioactive Polysaccharides from Microalgae: A Close Look at the Biomedical Applications
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Mariany C, Depra, Rosangela R, Dias, Mariana M, Maroneze, Tatiele C, Nascimento, Ihana A, Severo, Leila Q, Zepka, and Eduardo, Jacob-Lopes
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Bioengineering ,Applied Microbiology and Biotechnology ,Biotechnology - Abstract
Abstract: There is a current tendency towards bioactive natural products that can be used in different areas such as food, pharmaceutical, and biomedical. In the last decades, polysaccharides have attracted increasing interest because of their potent nontoxic effects, therapeutic properties, and diversified range of applications. Polysaccharides are complex and heterogeneous macromolecules constituted of different monosaccharides and, in some cases, of glucuronic acid and sulphate groups. Polysaccharides with biological activity can be derived from plants, animals and microorganisms, especially microalgae. Microalgae are considered one of the most promising sources of these compounds that have already proved to have several important biological properties. In this sense, our objective is to elucidate the use of bioactive polysaccharides from microalgae in biomedical applications, emphasizing the biological activity of these compounds. Furthermore, the microalgal biomass production systems and polysaccharides extraction methods were presented and discussed.
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- 2023
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6. Topical Mosquito Repellent Formulations for Enhanced Repellency Time and Reduced Toxicity
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Vânia Rodrigues Leite-Silva, Celio Takashi Higuchi, Newton Andreo Filho, Patricia Santos Lopes, and Jeffrey Ernest Grice
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Pharmaceutical Science - Abstract
Abstract: Mosquito-borne diseases such as dengue, malaria, yellow fever, chikungunya and Zika virus affect millions of people worldwide each year. Vector control and personal protection are very important to minimize the spread of diseases, and the use of repellent is an economical practice to prevent them. The application of repellent, which acts on the skin to form a vapor layer with a repellent odor to mosquitos, is recommended as an economical prevention and practice. The natural botanical product Citronella is an effective mosquito repellent due to the high concentrations of active chemical constituents present, notably terpenic alcohols. However, citronella tends to evaporate quickly from the skin surface, resulting in a rapid loss of activity. Strategies to increase repellency time, while at the same time minimizing toxicity, are major focuses of research and development in natural repellent products. Here we highlight the role of extended-release systems (ERS) of citronella oil in this approach.
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- 2023
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7. Effectiveness of a New App in Improving Oral Hygiene in Orthodontic Patients: A Pilot Study
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Raquel Lopes dos Santos, Manuela da Silva Spinola, Ellen Carvalho, Denis Clay Lopes dos Santos, Naile Dame-Teixeira, and Debora Heller
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General Dentistry - Abstract
The aim of this randomised clinical trial was to evaluate the effects of a mobile application (app) on the oral hygiene (OH) of adolescents undergoing fixed orthodontic treatment.Eight volunteers (14-19 years old) were randomly allocated to the experimental or control groups. Volunteers in the control group received standard OH (SOH) instructions, whilst volunteers in the experimental group received SHO + OH guidance and motivation through an app tailor-made for this study. Clinical assessments were made using the visible plaque index (VPI) and gingival bleeding index (GBI) at 5 different time points: before orthodontic device installation (T0); at baseline (T1); and 30 (T2), 60 (T3), and 90 (T4) days after randomisation. Significant differences were evaluated using Student t test and multilevel logistic regression analysis.Although no significant difference could be observed, VPI at T1 and T2 were lower for volunteers in the experimental group (33.20 ± 19.29; 32.10 ± 7.72) than for the volunteers in the control group (42.11 ± 8.56; 43.59 ± 34.71). The same was observed for GBI, in which volunteers in the experimental group presented lower GBI at T1 and T2 (12.70 ± 8.10; 13.72 ± 7.39) than volunteers in the control group (27.53 ± 17.89; 20.38 ± 9.95). Good acceptance for using the app was shown by volunteers.This study shows the potential utility of the mobile app for improving the OH of adolescents.
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- 2023
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8. Artificial intelligence applied to lawyers’ appraisals
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Susana Almeida Lopes, Marta Aranha Conceição, João Francisco Santos, Madalena Duarte Ferreira, José Sintra, and João Almeida Lopes
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Strategy and Management ,Law - Published
- 2023
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9. Ultrassonografia no rastreio da restrição do crescimento fetal: um 'padrão ouro' de baixo custo
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Martina Frazão Lopes Cavalcanti, Thomas Bernardes Lopes, Gabriela Correia de Araújo Novais, Julia Manuella Mendonça De Albuquerque, Ana Carolina Oliveira Sousa, Erickson Franklin Andrade Barros Brandão, Carla Santana Mariano Campos Sobral, and José Antônio Morais Martins
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Marketing ,Pharmacology ,Organizational Behavior and Human Resource Management ,Strategy and Management ,Drug Discovery ,Pharmaceutical Science - Abstract
Introdução: A restrição do crescimento fetal (RCF), também conhecida como restrição do crescimento intrauterino (RCIU) refere-se à incapacidade do feto de atingir seu potencial de crescimento adequado no útero devido a várias razões adversas. O crescimento fetal anormal está associado com risco aumentado de mortalidade e morbidade perinatal e desfecho neonatal adverso em longo termo. Os avanços nas técnicas de monitoramento fetal, possibilitaram uma melhor avaliação fetal e, consequentemente, uma melhor compreensão da história natural dessa condição. Dessa forma, o presente estudo buscou avaliar a importância do uso da ultrassonografia como método de rastreio e diagnostico da restrição do crescimento fetal (RCF). Métodos: Trata-se de uma revisão integrativa de literatura, com informações retiradas da base de dados Medline (via Pubmed). Utilizou-se os descritores e termos livre: “Ultrasound”, “Screening”, “Fetal growth restriction” com o auxílio do operador booleano AND. Aplicou-se, ainda, o filtro de artigos publicados durantes os anos de 2020-2023, sem mais restrições. Resultados e Discussão: A RCF é definida como a falha em atingir o potencial de crescimento do feto, causada por um processo patológico, mais comumente insuficiência placentária. O diagnóstico pode ser feito por meio do exame físico, da medida da altura de fundo ou da ultrassonografia, sendo a ultrassonografia o método mais preciso para o diagnóstico da RCF. A avaliação da suspeita de RCF geralmente se inicia quando se observa que o tamanho fetal estimado está abaixo de um limiar definido de normalidade para a idade gestacional, denominado pequeno para a idade gestacional (PIG), ou quando se observa um declínio no percentil de crescimento. Conclusão: A restrição de crescimento fetal continua sendo um problema obstétrico complexo associado a um risco aumentado de desfechos perinatais adversos. Assim, o diagnóstico e a intervenção precoces são essenciais para alcançar um melhor prognóstico, o que ressalta a importância de exames ultrassonográficos precisos.
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- 2023
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10. Aspectos clínicos e epidemiológicos dos acidentes por serpentes peçonhentas notificados no estado de Minas Gerais e sua prevalência no período de 2015 a 2020
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Thais Ligia Santos, Marcelo Lopes Cardoso, Lívia Maria Lopes Pereira, José Carlos Leal, and Ivani Pose Martins
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Geography, Planning and Development ,General Earth and Planetary Sciences ,Water Science and Technology - Abstract
Introdução: os acidentes causados por serpentes venenosas são considerados problemas de saúde pública. Objetivo: identificar o padrão e a prevalência de acidentes ofídicos dos gêneros Bothrops, Crotalus e Micrurus no período de 2015 a 2020, em Minas Gerais. Metodologia: realizou-se um levantamento das notificações, registradas no SINAN, de acidentes causados por serpentes dos gêneros Bothrops, Crotalus e Micrurus, em Minas Gerais, no período de 2015 a 2020. Os dados foram tabulados em Microsoft® Excel e SPSS®, versão 15.0. O tratamento estatístico dos dados foi por análise univariada. Para o cálculo da razão de prevalência (RP), de cada item, foram considerados os acidentes com as três espécies estudadas em relação aos acidentes com os demais animais peçonhentos. Foram considerados significativos, valores de p≤0,05. Resultados: No período aconteceram 15387 acidentes ofídicos, causados por serpentes dos gêneros Bothrops, Crotalus e Micrurus, em Minas Gerais, com mais registros na época das chuvas. O ano de 2020 teve maior número de ocorrências (18,38%). Do total, mais da metade (63,58%) aconteceu nos primeiros 4 anos. O maior número de acidentes foi ocasionado pelo gênero Bothrops. A faixa etária mais atingida estava entre 30 a 49 anos. Em relação ao grau de instrução 42,23% das pessoas tinham ensino fundamental incompleto. A maior parte das vítimas foi atendida na primeira hora após o acidente e os casos, classificados como leve. A maioria dos casos evoluíram para cura apesar da ocorrência de óbitos. Conclusão: a maioria dos acidentes causados por serpentes são do gênero Bothrops.
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- 2023
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11. Uma revisão integrativa sobre a Colangite Biliar Primária
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Marcos Oliveira Lima Rocha, Lucas Nunes de Freitas, Renato Aguiar Figueiredo Filho, Vanessa Araújo Alves, Giovanna Xavier Toledo, Daniel Henrique Santiago Leon Dos Santos, Guilherme da Costa Valente, Marcela da Costa Valente, Mayara Regina Rodrigues Alves Caverzan, Victória Luiza Ferrao Chaves, João Pedro Faria Franco, João Vitor de Queiroz Guedes, Sâmia Souza Dos Santos, Gabriella Moreira Bueno, Maria Eduarda Lopes Lorensini, Rafaela Angela Martins, Pedro Henrique Barbozane Molina, Victor Cunha de Albuquerque, Thaís ribeiro Vieira, Ana Luisa Lopes Callou Veras, Jessica Torres Scherr, Diego Onilton Costa Sales, Vinícius Mendes Nunes, Júlio Cesar Brito Da Costa, and Emmanuella Bruno Alencar
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Marketing ,Pharmacology ,Organizational Behavior and Human Resource Management ,Strategy and Management ,Drug Discovery ,Pharmaceutical Science - Abstract
A colangite biliar primária, um novo nome para a cirrose biliar primária, é uma doença colestática de etiologia autoimune e representa a primeira causa de colestase intra-hepática. Caracteriza-se pela destruição de pequenos dutos biliares ligados à infiltração de linfócitos, com prevalência de 10 a 40 por 100.000 habitantes no mundo. Este estudo teve como objetivo refletir sobre novas informações a respeito da colangite biliar primária. Para isso, foi realizada uma revisão integrativa de literatura, selecionando artigos publicados nas bases de dados Medical Literature Analysis and Retrieval System Online e Literatura Latino-americana e do Caribe em Ciências da Saúde. A partir da análise qualitativa dos dados, obteve-se como conclusão as seguintes descobertas: A PBC é um problema de saúde raro e mal diagnosticado; não há conhecimento ainda sobre as razões da predominância dessa da CBP em mulheres, resposta à terapêutica, distribuição geográfica e mortalidade entre sexos; os casos dessa doença são assintomáticos; a qualidade de vida dos pacientes é comprometida com o agravamento dos casos, onde apresentam inicialmente sinais de prurido (20 a 70% dos casos) e fadiga (entre 50% a 78% dos pacientes); exames de biópsica hepática podem ser tranquilamente substituídos por testes não-invasivos, em análises de rotina de bioquímica hepática; a possiblidade de diagnosticar a PBC pode ser diagnosticada partindo de fatores biológicos exclusivos que indicam a presença de anticorpos anti-mitocondriais e uma elevação da fosfatase alcalina. No entanto é quase possível que o PBC seja soronegativo; a etiologia da CBP não sendo encontra clara, sendo o tratamento difícil; em caso de tratamento, utiliza-se mais ursodesoxicólico, ácido biliar hidrofílico natural que bloqueia a síntese hepática do colesterol, estimulando a síntese de ácidos biliares e restaurando o equilíbrio entre esses.
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- 2023
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12. A pedagogia hospitalar no Brasil em tempos de pandemia da COVID-19: se já era complexo
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Sônia Maria Maciel Lopes, Júlio César André, Zaida Aurora Sperli Geraldes Soler, Leonila Santos de Almeida Sasso, Tiago Roberto Lopes Moreno, and Laura Brenda Nunes Lopes
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General Medicine - Abstract
A educação no meio hospitalar envolve a atuação compartilhada de profissionais das áreas de pedagogia e da saúde, tais como, psicólogos, terapeutas ocupacionais, médicos e enfermeiros, cada um a seu modo buscando integrar as necessidades de atenção em saúde da criança ou do adolescente hospitalizado por longos períodos e, assim, impedido de frequentar a escola regular, formalmente instituída [...]
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- 2023
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13. Impact of Dietary Sugars on β-Cell Function
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Ananda Malta, Lucas Paulo Jacinto Saavedra, Scarlett Rodrigues Raposo, Gabriel Kian Guimarães Lopes, Maryana Debossan Fernandes, Letícia Ferreira Barbosa, Douglas Lopes Almeida, and Paulo Cezar de Freitas Mathias
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General Medicine - Abstract
Regular consumption of dietary sugars can cause significant damage to the β-cells. Almost a century after the discovery of insulin, it has been suggested that the frequent consumption of certain carbohydrates can damage pancreatic β-cells, causing disturbances in the regulation of insulin secretion. Most noncommunicable diseases, such as diabetes, obesity, and hypertension have a common origin, metabolic dysfunction, which is partly due to β-cell malfunction. In this article, we believed that sugars can lead to an imbalance in cellular metabolism, causing insulin exocytosis to dangerously increase or decrease blood insulin concentrations. In this study, we describe the major mechanism of insulin secretion and discuss the effects of sugar on pancreatic β-cells. Although many environmental factors strongly influence β-cells, occidental diet, including excess sugar, has been found to be the predominant factor that kills or disrupts the functioning of the unique cells that produce, store, and secrete insulin.
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- 2023
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14. ASSISTÊNCIA A GESTANTE COM ANEMIA FALCIFORME
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Vitoria Vilas Boas da Silva Bomfim, Hudson Nero Bárbara Silva, Felipe Dayrell Schoepfer, Rafaella Ribeiro Gomes Nogueira, Alex Fabricio Lopes, Deborah de Souza Bahia, Karolyne Lopes da Costa, Marília Draghetti, Daniela de Paula Goulart, and Mari Nei Clososki da Rocha
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Introdução: A anemia falciforme é uma doença genética que afeta a hemoglobina, proteína responsável por transportar o oxigênio pelo corpo. Essa doença pode afetar a gestação, aumentando o risco de complicações para a mãe e para o feto. Objetivo: Descrever a assistência a gestante com anemia falciforme. Metodologia: Revisão integrativa de literatura, realizada na MEDLINE, LILACS e SciELO, por meio dos DeCS: Anemia Falciforme e Gravidez. Resultados e Discussão: A assistência de saúde à gestante com anemia falciforme é de extrema importância para garantir uma gestação segura e saudável. É fundamental que a assistência seja multidisciplinar e personalizada, envolvendo profissionais de diversas áreas, como médicos, enfermeiros, nutricionistas e psicólogos. Essa abordagem integrada permite uma avaliação completa da gestante e a identificação precoce de complicações, além de possibilitar um tratamento individualizado e efetivo. Considerações Finais: Devido à complexidade de estar grávida, uma pessoa acometida por anemia falciforme, precisa realizar adequadamente o pré-natal de alto risco, de modo que, dessa forma, a enfermagem desempenhe a função de acompanhar, esclarecer dúvidas e assistência à gestante durante todo o período gestacional.
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- 2023
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15. MICROSTRAIN OVERVIEW IN IMPLANT-SUPPORTED PROSTHESES IN ATROPHIC MAXILLARY AREA
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Jefferson David Melo de Matos, Daher Antonio Queiroz, Mateus Favero Barra Grande, Robertson Wagner Carvalho Batista, Rogério Heládio Lopes Motta, Adriano Baldotto Barbosa, Marcelo Lucchesi Teixeira, John Eversong Lucena de Vasconcelos, Marco Antonio Bottino, and Guilherme da Rocha Scalzer Lopes
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- 2023
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16. PREPARATION OF PARAFFIN MICROSPHERES BY SUSPENSION USING PVP AS A STABILIZING AGENT
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Karine Lopes Resende, Toni Jeferson Lopes, and Gerson Avelino Fernandes
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- 2023
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17. Necessidades de leitura acadêmica e uso de rubricas: o caso na Biologia
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Carolina Assis Lopes and Vera Lúcia Lopes Cristovão
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Ao ingressarem na universidade, estudantes entram em contato com diversos gêneros e atividades que requerem diferentes tipos de letramentos. Na área da biologia, uma delas refere-se à leitura de textos de divulgação científica (TDC) em língua inglesa. Assim, ofertamos uma oficina a estudantes do primeiro ano do curso de Ciências Biológicas da UEL abordando esta atividade. Fundamentado em estudos sobre o gênero TDC e rubricas, este trabalho visa mapear necessidades de estudantes quanto à leitura em língua inglesa e analisar o efeito do uso de rubricas na leitura de TDC. A natureza desta pesquisa é de método misto, sendo os dados gerados por meio de um questionário de análise de necessidades, avaliação inicial (pré-teste) e final (pós-teste) de leitura de TDC em língua inglesa. No pré-teste, a maioria dos estudantes obteve um saldo positivo entre respostas satisfatórias e não satisfatórias. Já no pós-teste, é possível perceber uma considerável melhora no desempenho. Sendo assim, a rubrica utilizada na oficina pode ter contribuído para uma melhor leitura de TDC.
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- 2023
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18. Apendicectomia: Benefícios da videolaparoscopia comparada à convencional no Brasil em pacientes pediátricos
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Danielle Lopes Porto, Milena Freire Guinazi, Ana Luísa Siqueira Resende, Viviany Alves Ferreira Da Mata, Maria Cecília Marques Lopes, and Leandro Vaz da Silva Borges
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General Medicine - Abstract
INTRODUÇÃO: A apendicite aguda é resultado da infecção e inflamação do apêndice, sendo comum na pediatria. O tratamento é cirúrgico e existem opções para a realização, sendo: apendicectomia aberta ou videolaparoscópica. METODOLOGIA: Revisão de literatura, na base de dados Google Scholar. Palavras-chave: apendicectomia aberta, videolaparoscópica, convencional. Foram descartados os artigos que não associavam as variáveis selecionadas pelo trabalho e selecionados seis artigos. RESULTADOS: A média do tempo de permanência hospitalar foi de 3,5 dias para a videolaparoscopia e 4,7 para a aberta. A taxa de pacientes que apresentaram complicações no pós-operatório foi de 5% na videolaparoscópica e 30% em cirurgia aberta. A videolaparoscopia apresentou uma redução de 60% de mortalidade em relação a via aberta. CONCLUSÕES: A apendicectomia videolaparoscópica mostrou significativa vantagem em relação à aberta. Entretanto, ainda são necessários estudos complementares para melhor comparar as duas técnicas nessa faixa etária.
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- 2023
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19. Infarto agudo do miocárdio piora a dependência, atividade física e o estado emocional em idosos
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Bruno Henrique Fiorin, Lucas Dalvi Armond Rezende, Manoela Ferreira Martins, Gabrielly Dos Santos Moreira, Emanuelle De Souza Theotonio, Walckíria Garcia Romero Sipolatt, Andressa Bolsoni Lopes, and Rita Simone Lopes Moreira
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Introdução: Qualidade de vida (QV) não é sinônimo de saúde, mas está relacionado ao bem-estar físico, mental e socioeconômico e à influência de fatores ambientais. O Myocardial Infarction Dimensional Assessment Scale (MIDAS) é um instrumento desenvolvido com o intuito de medir os aspectos mais específicos de pacientes que sofreram Infarto Agudo do Miocárdio (IAM), que não são capazes de serem respondidas por outros instrumentos genéricos. Objetivos: Avaliar a qualidade de vida em idosos após infarto agudo do miocárdio. Métodos: Estudo descritivo, de corte transversal e de abordagem quantitativa. Os dados foram coletados em um hospital referência em cardiologia. Para coleta de dados, foram utilizados dois instrumentos. O primeiro é um instrumento elaborado pelos pesquisadores para caracterizar sua amostra e avaliar os fatores de riscos para doenças cardiovasculares. O segundo é a Escala de Avaliação Multidimensional pós-Infarto Agudo do Miocárdio, validado para língua portuguesa, que visa avaliar a qualidade de vida. Resultados: Participaram 183 idosos, de 60 a 91 anos. 129 (70,5%) deles são hipertensos, 88 (48,1%) diabéticos, 94 (51,4%) fumantes, 74 (40,4%) consumiam bebida alcoólica, 57 (31,1%) relataram estar deprimidos frequentemente e 92 (50,3%) afirmaram que ocorreram mudanças na qualidade de vida. Os domínios que obtiveram melhor resultados foram os “efeitos colaterais” e a “dieta”. Os domínios que apresentaram piores resultados foram “dependência” e “atividade física”. Conclusão: Idosos apresentaram mudanças na qualidade de vida pós-infarto agudo do miocárdio e ainda reforçou a prevalência de fatores de riscos cardiovasculares.
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- 2023
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20. Search for the radiative Ξb− → Ξ − γ decay
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Aaij, R., Abdelmotteleb, A. S. W., Abellán Beteta, C., Ackernley, T., Adeva, B., Adinolfi, M., Afsharnia, H., Aidala, C. A., Aiola, S., Ajaltouni, Z., Akar, S., Albrecht, J., Alessio, F., Alexander, M., Alfonso Albero, A., Aliouche, Z., Alkhazov, G., Alvarez Cartelle, P., Amato, S., Amey, J. L., Amhis, Y., An, L., Anderlini, L., Andreianov, A., Andreotti, M., Archilli, F., Artamonov, A., Artuso, M., Arzymatov, K., Aslanides, E., Atzeni, M., Audurier, B., Bachmann, S., Bachmayer, M., Back, J. J., Baladron Rodriguez, P., Balagura, V., Baldini, W., Baptista Leite, J., Barlow, R. J., Barsuk, S., Barter, W., Bartolini, M., Baryshnikov, F., Basels, J. M., Bashir, S., Bassi, G., Batsukh, B., Battig, A., Bay, A., Beck, A., Becker, M., Bedeschi, F., Bediaga, I., Beiter, A., Belavin, V., Belin, S., Bellee, V., Belous, K., Belov, I., Belyaev, I., Bencivenni, G., Ben-Haim, E., Berezhnoy, A., Bernet, R., Berninghoff, D., Bernstein, H. C., Bertella, C., Bertolin, A., Betancourt, C., Betti, F., Bezshyiko, I., Bhasin, S., Bhom, J., Bian, L., Bieker, M. S., Bifani, S., Billoir, P., Birch, M., Bishop, F. C. R., Bitadze, A., Bizzeti, A., Bjørn, M., Blago, M. P., Blake, T., Blanc, F., Blusk, S., Bobulska, D., Boelhauve, J. A., Boente Garcia, O., Boettcher, T., Boldyrev, A., Bondar, A., Bondar, N., Borghi, S., Borisyak, M., Borsato, M., Borsuk, J. T., Bouchiba, S. A., Bowcock, T. J. V., Boyer, A., Bozzi, C., Bradley, M. J., Braun, S., Brea Rodriguez, A., Brodski, M., Brodzicka, J., Brossa Gonzalo, A., Brundu, D., Buonaura, A., Buonincontri, L., Burke, A. T., Burr, C., Bursche, A., Butkevich, A., Butter, J. S., Buytaert, J., Byczynski, W., Cadeddu, S., Cai, H., Calabrese, R., Calefice, L., Calero Diaz, L., Cali, S., Calladine, R., Calvi, M., Calvo Gomez, M., Camargo Magalhaes, P., Campana, P., Campoverde Quezada, A. F., Capelli, S., Capriotti, L., Carbone, A., Carboni, G., Cardinale, R., Cardini, A., Carli, I., Carniti, P., Carus, L., Carvalho Akiba, K., Casais Vidal, A., Casse, G., Cattaneo, M., Cavallero, G., Celani, S., Cerasoli, J., Cervenkov, D., Chadwick, A. J., Chapman, M. G., Charles, M., Charpentier, P., Chatzikonstantinidis, G., Chavez Barajas, C. A., Chefdeville, M., Chen, C., Chen, S., Chernov, A., Chobanova, V., Cholak, S., Chrzaszcz, M., Chubykin, A., Chulikov, V., Ciambrone, P., Cicala, M. F., Cid Vidal, X., Ciezarek, G., Clarke, P. E. L., Clemencic, M., Cliff, H. V., Closier, J., Cobbledick, J. L., Coco, V., Coelho, J. A. B., Cogan, J., Cogneras, E., Cojocariu, L., Collins, P., Colombo, T., Congedo, L., Contu, A., Cooke, N., Coombs, G., Corredoira, I., Corti, G., Costa Sobral, C. M., Couturier, B., Craik, D. C., Crkovská, J., Cruz Torres, M., Currie, R., Da Silva, C. L., Dadabaev, S., Dai, L., Dall’Occo, E., Dalseno, J., D’Ambrosio, C., Danilina, A., D’Argent, P., Davies, J. E., Davis, A., De Aguiar Francisco, O., De Bruyn, K., De Capua, S., De Cian, M., De Miranda, J. M., De Paula, L., De Serio, M., De Simone, D., De Simone, P., de Vries, J. A., Dean, C. T., Decamp, D., Del Buono, L., Delaney, B., Dembinski, H. -P., Dendek, A., Denysenko, V., Derkach, D., Deschamps, O., Desse, F., Dettori, F., Dey, B., Di Cicco, A., Di Nezza, P., Didenko, S., Dieste Maronas, L., Dijkstra, H., Dobishuk, V., Dong, C., Donohoe, A. M., Dordei, F., dos Reis, A. C., Douglas, L., Dovbnya, A., Downes, A. G., Dudek, M. W., Dufour, L., Duk, V., Durante, P., Durham, J. M., Dutta, D., Dziurda, A., Dzyuba, A., Easo, S., Egede, U., Egorychev, V., Eidelman, S., Eisenhardt, S., Ek-In, S., Eklund, L., Ely, S., Ene, A., Epple, E., Escher, S., Eschle, J., Esen, S., Evans, T., Falabella, A., Fan, J., Fan, Y., Fang, B., Farry, S., Fazzini, D., Féo, M., Fernandez Prieto, A., Fernez, A. D., Ferrari, F., Ferreira Lopes, L., Ferreira Rodrigues, F., Ferreres Sole, S., Ferrillo, M., Ferro-Luzzi, M., Filippov, S., Fini, R. A., Fiorini, M., Firlej, M., Fischer, K. M., Fitzgerald, D. S., Fitzpatrick, C., Fiutowski, T., Fkiaras, A., Fleuret, F., Fontana, M., Fontanelli, F., Forty, R., Foulds-Holt, D., Franco Lima, V., Franco Sevilla, M., Frank, M., Franzoso, E., Frau, G., Frei, C., Friday, D. A., Fu, J., Fuehring, Q., Funk, W., Gabriel, E., Gaintseva, T., Gallas Torreira, A., Galli, D., Gambetta, S., Gan, Y., Gandelman, M., Gandini, P., Gao, Y., Garau, M., Garcia Martin, L. M., Garcia Moreno, P., García Pardiñas, J., Garcia Plana, B., Garcia Rosales, F. A., Garrido, L., Gaspar, C., Geertsema, R. E., Gerick, D., Gerken, L. L., Gersabeck, E., Gersabeck, M., Gershon, T., Gerstel, D., Ghez, P., Gibson, V., Giemza, H. K., Gilman, A. L., Giovannetti, M., Gioventù, A., Gironella Gironell, P., Giubega, L., Giugliano, C., Gizdov, K., Gkougkousis, E. L., Gligorov, V. V., Göbel, C., Golobardes, E., Golubkov, D., Golutvin, A., Gomes, A., Gomez Fernandez, S., Goncalves Abrantes, F., Goncerz, M., Gong, G., Gorbounov, P., Gorelov, I. V., Gotti, C., Govorkova, E., Grabowski, J. P., Grammatico, T., Granado Cardoso, L. A., Graugés, E., Graverini, E., Graziani, G., Grecu, A., Greeven, L. M., Grieser, N. A., Griffith, P., Grillo, L., Gromov, S., Gruberg Cazon, B. R., Gu, C., Guarise, M., Günther, P. A., Gushchin, E., Guth, A., Guz, Y., Gys, T., Hadavizadeh, T., Haefeli, G., Haen, C., Haimberger, J., Halewood-leagas, T., Hamilton, P. M., Hammerich, J. P., Han, Q., Han, X., Hancock, T. H., Hansmann-Menzemer, S., Harnew, N., Harrison, T., Hasse, C., Hatch, M., He, J., Hecker, M., Heijhoff, K., Heinicke, K., Hennequin, A. M., Hennessy, K., Henry, L., Heuel, J., Hicheur, A., Hill, D., Hilton, M., Hollitt, S. E., Hu, J., Hu, W., Hu, X., Huang, W., Huang, X., Hulsbergen, W., Hunter, R. J., Hushchyn, M., Hutchcroft, D., Hynds, D., Ibis, P., Idzik, M., Ilin, D., Ilten, P., Inglessi, A., Ishteev, A., Ivshin, K., Jacobsson, R., Jakobsen, S., Jans, E., Jashal, B. K., Jawahery, A., Jevtic, V., Jiang, F., John, M., Johnson, D., Jones, C. R., Jones, T. P., Jost, B., Jurik, N., Kalavan Kadavath, S. H., Kandybei, S., Kang, Y., Karacson, M., Karpov, M., Keizer, F., Kenzie, M., Ketel, T., Khanji, B., Kharisova, A., Kholodenko, S., Kirn, T., Kirsebom, V. S., Kitouni, O., Klaver, S., Klimaszewski, K., Kmiec, M. R., Koliiev, S., Kondybayeva, A., Konoplyannikov, A., Kopciewicz, P., Kopecna, R., Koppenburg, P., Korolev, M., Kostiuk, I., Kot, O., Kotriakhova, S., Kravchenko, P., Kravchuk, L., Krawczyk, R. D., Kreps, M., Kress, F., Kretzschmar, S., Krokovny, P., Krupa, W., Krzemien, W., Kucewicz, W., Kucharczyk, M., Kudryavtsev, V., Kuindersma, H. S., Kunde, G. J., Kvaratskheliya, T., Lacarrere, D., Lafferty, G., Lai, A., Lampis, A., Lancierini, D., Lane, J. J., Lane, R., Lanfranchi, G., Langenbruch, C., Langer, J., Lantwin, O., Latham, T., Lazzari, F., Le Gac, R., Lee, S. H., Lefèvre, R., Leflat, A., Legotin, S., Leroy, O., Lesiak, T., Leverington, B., Li, H., Li, P., Li, S., Li, Y., Li, Z., Liang, X., Lin, T., Lindner, R., Lisovskyi, V., Litvinov, R., Liu, G., Liu, H., Liu, S., Lobo Salvia, A., Loi, A., Lomba Castro, J., Longstaff, I., Lopes, J. H., Lopez Solino, S., Lovell, G. H., Lu, Y., Lucchesi, D., Luchuk, S., Lucio Martinez, M., Lukashenko, V., Luo, Y., Lupato, A., Luppi, E., Lupton, O., Lusiani, A., Lyu, X., Ma, L., Ma, R., Maccolini, S., Machefert, F., Maciuc, F., Macko, V., Mackowiak, P., Maddrell-Mander, S., Madejczyk, O., Madhan Mohan, L. R., Maev, O., Maevskiy, A., Maisuzenko, D., Majewski, M. W., Malczewski, J. J., Malde, S., Malecki, B., Malinin, A., Maltsev, T., Malygina, H., Manca, G., Mancinelli, G., Manuzzi, D., Marangotto, D., Maratas, J., Marchand, J. F., Marconi, U., Mariani, S., Marin Benito, C., Marinangeli, M., Marks, J., Marshall, A. M., Marshall, P. J., Martellotti, G., Martinazzoli, L., Martinelli, M., Martinez Santos, D., Martinez Vidal, F., Massafferri, A., Materok, M., Matev, R., Mathad, A., Mathe, Z., Matiunin, V., Matteuzzi, C., Mattioli, K. R., Mauri, A., Maurice, E., Mauricio, J., Mazurek, M., Mccann, M., Mcconnell, L., Mcgrath, T. H., Mchugh, N. T., Mcnab, A., Mcnulty, R., Mead, J. V., Meadows, B., Meier, G., Meinert, N., Melnychuk, D., Meloni, S., Merk, M., Merli, A., Meyer Garcia, L., Mikhasenko, M., Milanes, D. A., Millard, E., Milovanovic, M., Minard, M. -N., Minotti, A., Minzoni, L., Mitchell, S. E., Mitreska, B., Mitzel, D. S., Mödden, A., Mohammed, R. A., Moise, R. D., Mombächer, T., Monroy, I. A., Monteil, S., Morandin, M., Morello, G., Morello, M. J., Moron, J., Morris, A. B., Morris, A. G., Mountain, R., Mu, H., Muheim, F., Mulder, M., Müller, D., Müller, K., Murphy, C. 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Particles and field ,Nuclear and High Energy Physics ,B physics, Flavor physics, Hadron-Hadron scattering (experiments), Rare decay ,010308 nuclear & particles physics ,B physic ,01 natural sciences ,HEP ,B physics ,LHCb ,Flavor physics ,Hadron collider ,Rare decay ,Hadron-Hadron scattering (experiments) ,TheoryofComputation_ANALYSISOFALGORITHMSANDPROBLEMCOMPLEXITY ,Flavor physic ,0103 physical sciences ,Physic ,LHC ,010306 general physics - Abstract
The first search for the rare radiative decay $$ {\Xi}_b^{-} $$ Ξ b − → Ξ−γ is performed using data collected by the LHCb experiment in proton-proton collisions at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 5.4 fb−1. The $$ {\Xi}_b^{-} $$ Ξ b − → Ξ−J/ψ channel is used as normalization. No $$ {\Xi}_b^{-} $$ Ξ b − → Ξ−γ signal is found and an upper limit of $$ \mathcal{B} $$ B ($$ {\Xi}_b^{-} $$ Ξ b − → Ξ−γ) < 1.3 × 10−4 at 95% confidence level is obtained.
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- 2022
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21. Analysis of Psychological Symptoms Following Disclosure of Amyloid-Positron Emission Tomography Imaging Results to Adults With Subjective Cognitive Decline
- Author
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Caprioglio, Camilla, Ribaldi, Federica, Visser, Leonie N. C., Minguillon, Carolina, Collij, Lyduine E., Grau-Rivera, Oriol, Zeyen, Philip, Molinuevo, José Luis, Gispert, Juan Domingo, Garibotto, Valentina, Moro, Christian, Walker, Zuzana, Edison, Paul, Demonet, Jean-François, Barkhof, Frederik, Scheltens, Philip, Alves, Isadora Lopes, Gismondi, Rossella, Farrar, Gill, Stephens, Andrew W., Jessen, Frank, Frisoni, Giovanni B., Altomare, Daniele, Abdelnour, Carla, Aguilera, Nuria, Aksman, Leon, Alarcón-Martín, Emilio, Alegret, Montse, Alonso-Lana, Silvia, Andersen, Pia, Arab, Majd, Aspö, Malin, Bader, Ilona, Bader, Ilse, Banton, Nigel, Barnes, Rodrigo, Barrie, Dawn, Battle, Mark, Belén Collado, Ana, Bellet, Julie, Berkhof, Johannes, Biger, Marine, Birck, Cindy, Bischof, Gerard, Boada, Mercè, Boellaard, Ronald, Bogdanovic, Nenad, Bollack, Ariane, Bombois, Stéphanie, Borg, Stefan, Borjesson-Hanson, Anne, Boskov, Vladimir, Boutantin, Justine, Boutoleau-Bretonniere, Claire, Bouwman, Femke, Breuilh, Laetitia, Bringman, Eva, Brunel, Baptiste, Bucci, Marco, Buckley, Chris, Buendía, Mar, Bullich, Santi, Calvet, Anna, Cañada, Laia, Cañada, Marta, Cardoso, Jorge, Carlier, Jasmine, Carre, Elise, Carrie, Isabelle, Cassagnaud, Pascaline, Cassol, Emmanuelle, Castilla-Martí, Miguel, Cazalon, Elodie, Chaarriau, Tiphaine, Chaigeau, Rachel, Chalmers, Taylor, Clerc, Marie-Thérèse, Clerigue, Montserrat, Cognat, Emmanuel, Coll, Nina, Collij, Lyduine E, Connely, Peter, Cordier, Elodie, Costes, Corine, Coulange, Camille, Courtemanche, Hélène, Creisson, Eric, Crinquette, Charlotte, Cuevas, Rosario, Cufi, Marie-Noëlle, Dardenne, Sophie, de Arriba, Maria, de Costa Luis, Casper, de Gier, Yvonne, de Verbizier Lonjon, Delphine, Dekker, Veronique, Dekyndt, Bérengère, Delbeuck, Xavier, Delrieu, Julien, Deramecourt, Vincent, Desclaux, Françoise, Diaz, Carlos, Diego, Susana, Djafar, Mehdi, Dölle, Britta, Doull, Laura, Dricot, Laurence, Drzezga, Alexander, Dubois, Bruno, Dumont, Julien, Dumur, Jean, Dumurgier, Julien, Dvorak, Martin, Ecay, Mirian, Escher, Claus, Estanga, Ainara, Esteban, Ester, Fanjaud, Guy, Fauria, Karine, Felez Sanchez, Marta, Feukam Talla, Patrick, Ford, Lisa, Frisoni, Giovanni B, Fuster, David, Gabelle, Audrey, Gaubert, Sinead, Gauci, Cédric, Geldhof, Christine, Georges, Jean, Ghika, Joseph, González, Elena, Goovaerts, Valerie, Goulart, Denis Mariano, Grasselli, Caroline, Gray, Katherine, Greensmith, Martin, Grozn, Laure, Guillemaud, Céline, Gunn, Fiona, Guntur Ramkumar, Prasad, Hagman, Göran, Hansseuw, Bernard, Heeman, Fiona, Hendriks, Janine, Himmelmann, Jakob, Hitzel, Anne, Hives, Florent, Hoenig, Merle, Hourrègue, Claire, Hudson, Justine, Huguet, Jordi, Ibarria, Marta, Iidow, Ifrah, Indart, Sandrine, Ingala, Silvia, Ivanoiu, Adrian, Jacquemont, Charlotte, Jelic, Vesna, Jiao, Jieqing, Jofresa, Sara, Jonsson, Cathrine, Kaliukhovich, Dzmitry, Kern, Silke, Kivipelto, Miia, Knezevic, Iva, Kuchcinski, Grégory, Laforce, Manon, Lafuente, Asunción, Lala, Françoise, Lammertsma, Adriaan, Lax, Michelle, Lebouvier, Thibaud, Lee, Ho-Yun, Lee, Lean, Leeuwis, Annebet, Lefort, Amandine, Legrand, Jean-François, Leroy, Mélanie, Lesoil Markowski, Constance, Levy, Marcel, Lhommel , Renaud, Lopes, Renaud, Lopes Alves, Isadora, Lorenzini, Luigi, Lorette, Adrien, Luckett, Emma, Lundin, Marie, Mackowiak, Marie-Anne, Malotaux, Vincent, Manber, Richard, Manyakov, Nikolay, Markiewicz, Pawel, Marne, Paula, Marquié, Marta, Martín, Elvira, Martínez, Joan, Martinez Lage, Pablo, Mastenbroek, Sophie E, Maureille, Aurélien, Meersmans, Karen, Mett, Anja, Milne, Joseph, Minguillón, Carolina, Modat, Marc, Montrreal, Laura, Müller, Theresa, Muniz, Graciela, Mutsarts, Henk Jan, Nilsson, Ted, Ninerola, Aida, Nordberg, Agneta, Novaes, Wilse, Nuno Carmelo Pires Silva, Joao, Operto, Greg, Orellana, Adela, Ousset, Pierre-Jean, Outteryck, Olivier, Pallardy, Amandine, Palombit, Alessandro, Pancho, Ana, Pappon, Martin, Paquet, Claire, Pariente, Jérémie, Pasquier, Florence, Payoux, Pierre, Peaker, Harry, Pelejà, Esther, Pennetier, Delphine, Pérez-Cordón, Alba, Perissinotti, Andrés, Perrenoud, Matthieu Paul, Petit, Sandrine, Petyt, Grégory, Pfeil, Julia, Pirotte, Blanche, Pla, Sandra, Plaza Wuthrich, Sonia, Poitrine, Lea, Pollet, Marianne, Poncelet, Jean-Benoit, Prior, John, Pruvo, Jean-Pierre, Putallaz, Pauline, Queneau, Mathieu, Quenon , Lisa, Rădoi, Andreea, Rafiq, Marie, Ramage, Fiona, Ramis, Maribel, Reinwald, Michael, Rios, Gonzalo, Ritchie, Craig, Rodriguez, Elena, Rollin, Adeline, Rouaud, Olivier, Sacuiu, Simona, Saint-Aubert, Laure, Sala, Arianna, Salabert, Anne-Sophie, Saldias, Jon, Salvadó, Gemma, Sanabria, Angela, Sannemann, Lena, Sastre, Nathalie, Savina, Daniela, Savitcheva, Irina, Schaeverbeke, Jolien, Schildermans, Carine, Schmidt, Mark, Schöll, Michael, Schuermans, Jeroen, Semah, Franck, Shekari, Mahnaz, Skoog, Ingmar, Sotolongo-Grau, Oscar, Stephens, Andrew, Stewart, Tiffany, Stutzmann, Jennyfer, Tait, Murray, Tárraga, Lluis, Tartari, Juan Pablo, Tysen-backstrom, Ann-christine, Valero, Sergi, Vallez Garcia, David, van Berckel, Bart N M, van Essen, Martijn, Van Laere, Koen, van Leur, Jeroen, van Maurik, Ingrid S, Vandenberghe, Rik, Vellas, Bruno, Virolinen, Jukka, Visser, Pieter Jelle, Walles, Håkan, Wallin, Emilia, Whitelaw, Grant, Wimberley, Catriona, Win , Zarni, Wink, Alle Meije, Wolz, Robin, Woodside, John, Yaqub, Maqsood, Zettergren, Anna, Medical Psychology, APH - Personalized Medicine, APH - Quality of Care, Radiology and nuclear medicine, Amsterdam Neuroscience - Neurodegeneration, Amsterdam Neuroscience - Brain Imaging, Amsterdam Neuroscience - Neuroinfection & -inflammation, CCA - Cancer Treatment and quality of life, CCA - Imaging and biomarkers, Neurology, Dekyndt, Bérengère, Delbeuck, Xavier, Delrieu, Julien, Demonet, Jean-François, Deramecourt, Vincent, Desclaux, Françoise, Diaz, Carlos, Diego, Susana, Djafar, Mehdi, Dölle, Britta, Doull, Laura, Dricot, Laurence, Drzezga, Alexander, Dubois, Bruno, Dumont, Julien, Dumur, Jean, Dumurgier, Julien, Dvorak, Martin, Ecay, Mirian, Edison, Paul, Escher, Claus, Estanga, Ainara, Esteban, Ester, Fanjaud, Guy, Farrar, Gill, Fauria, Karine, Felez Sanchez, Marta, Feukam Talla, Patrick, Ford, Lisa, Frisoni, Giovanni B, Fuster, David, Gabelle, Audrey, Garibotto, Valentina, Gaubert, Sinead, Gauci, Cédric, Geldhof, Christine, Georges, Jean, Ghika, Joseph, Gismondi, Rossella, Gispert, Juan Domingo, González, Elena, Goovaerts, Valerie, Goulart, Denis Mariano, Grasselli, Caroline, Grau-Rivera, Oriol, Gray, Katherine, Greensmith, Martin, Grozn, Laure, Guillemaud, Céline, Gunn, Fiona, Guntur Ramkumar, Prasad, Hagman, Göran, Hansseuw, Bernard, Heeman, Fiona, Hendriks, Janine, Himmelmann, Jakob, Hitzel, Anne, Hives, Florent, Hoenig, Merle, Hourrègue, Claire, Hudson, Justine, Huguet, Jordi, Ibarria, Marta, Iidow, Ifrah, Indart, Sandrine, Ingala, Silvia, Ivanoiu, Adrian, Jacquemont, Charlotte, Jelic, Vesna, Jessen, Frank, Jiao, Jieqing, Jofresa, Sara, Jonsson, Cathrine, Kaliukhovich, Dzmitry, Kern, Silke, Kivipelto, Miia, Knezevic, Iva, Kuchcinski, Grégory, Laforce, Manon, Lafuente, Asunción, Lala, Françoise, Lammertsma, Adriaan, Lax, Michelle, Lebouvier, Thibaud, Lee, Ho-Yun, Lee, Lean, Leeuwis, Annebet, Lefort, Amandine, Legrand, Jean-François, Leroy, Mélanie, Lesoil Markowski, Constance, Levy, Marcel, Lhommel, Renaud, Lopes, Renaud, Lopes Alves, Isadora, Lorenzini, Luigi, Lorette, Adrien, Luckett, Emma, Lundin, Marie, Mackowiak, Marie-Anne, Malotaux, Vincent, Manber, Richard, Manyakov, Nikolay, Markiewicz, Pawel, Marne, Paula, Marquié, Marta, Martín, Elvira, Martínez, Joan, Martinez Lage, Pablo, Mastenbroek, Sophie E, Maureille, Aurélien, Meersmans, Karen, Mett, Anja, Milne, Joseph, Minguillón, Carolina, Modat, Marc, Molinuevo, José Luis, Montrreal, Laura, Moro, Christian, Müller, Theresa, Muniz, Graciela, Mutsarts, Henk Jan, Nilsson, Ted, Ninerola, Aida, Nordberg, Agneta, Novaes, Wilse, Nuno Carmelo Pires Silva, Joao, Operto, Greg, Orellana, Adela, Ousset, Pierre-Jean, Outteryck, Olivier, Pallardy, Amandine, Palombit, Alessandro, Pancho, Ana, Pappon, Martin, Paquet, Claire, Pariente, Jérémie, Pasquier, Florence, Payoux, Pierre, Peaker, Harry, Abdelnour, Carla, Pelejà, Esther, Pennetier, Delphine, Pérez-Cordón, Alba, Perissinotti, Andrés, Perrenoud, Matthieu Paul, Petit, Sandrine, Petyt, Grégory, Pfeil, Julia, Pirotte, Blanche, Pla, Sandra, Aguilera, Nuria, Plaza Wuthrich, Sonia, Poitrine, Lea, Pollet, Marianne, Poncelet, Jean-Benoit, Prior, John, Pruvo, Jean-Pierre, Putallaz, Pauline, Queneau, Mathieu, Quenon, Lisa, Rădoi, Andreea, Aksman, Leon, Rafiq, Marie, Ramage, Fiona, Ramis, Maribel, Reinwald, Michael, Rios, Gonzalo, Ritchie, Craig, Rodriguez, Elena, Rollin, Adeline, Rouaud, Olivier, Sacuiu, Simona, Alarcón-Martín, Emilio, Saint-Aubert, Laure, Sala, Arianna, Salabert, Anne-Sophie, Saldias, Jon, Salvadó, Gemma, Sanabria, Angela, Sannemann, Lena, Sastre, Nathalie, Savina, Daniela, Savitcheva, Irina, Alegret, Montse, Schaeverbeke, Jolien, Scheltens, Philip, Schildermans, Carine, Schmidt, Mark, Schöll, Michael, Schuermans, Jeroen, Semah, Franck, Shekari, Mahnaz, Skoog, Ingmar, Sotolongo-Grau, Oscar, Alonso-Lana, Silvia, Stephens, Andrew, Stewart, Tiffany, Stutzmann, Jennyfer, Tait, Murray, Tárraga, Lluis, Tartari, Juan Pablo, Tysen-Backstrom, Ann-Christine, Valero, Sergi, Vallez Garcia, David, van Berckel, Bart N M, Altomare, Daniele, van Essen, Martijn, Van Laere, Koen, van Leur, Jeroen, van Maurik, Ingrid S, Vandenberghe, Rik, Vellas, Bruno, Virolinen, Jukka, Visser, Pieter Jelle, Walker, Zuzana, Walles, Håkan, Andersen, Pia, Wallin, Emilia, Whitelaw, Grant, Wimberley, Catriona, Win, Zarni, Wink, Alle Meije, Wolz, Robin, Woodside, John, Yaqub, Maqsood, Zettergren, Anna, Zeyen, Philip, Arab, Majd, Aspö, Malin, Bader, Ilona, Bader, Ilse, Banton, Nigel, Barkhof, Frederik, Barnes, Rodrigo, Barrie, Dawn, Battle, Mark, Belén Collado, Ana, Bellet, Julie, Berkhof, Johannes, Biger, Marine, Birck, Cindy, Bischof, Gerard, Boada, Mercè, Boellaard, Ronald, Bogdanovic, Nenad, Bollack, Ariane, Bombois, Stéphanie, Borg, Stefan, Borjesson-Hanson, Anne, Boskov, Vladimir, Boutantin, Justine, Boutoleau-Bretonniere, Claire, Bouwman, Femke, Breuilh, Laetitia, Bringman, Eva, Brunel, Baptiste, Bucci, Marco, Buckley, Chris, Buendía, Mar, Bullich, Santi, Calvet, Anna, Cañada, Laia, Cañada, Marta, Caprioglio, Camilla, Cardoso, Jorge, Carlier, Jasmine, Carre, Elise, Carrie, Isabelle, Cassagnaud, Pascaline, Cassol, Emmanuelle, Castilla-Martí, Miguel, Cazalon, Elodie, Chaarriau, Tiphaine, Chaigeau, Rachel, Chalmers, Taylor, Clerc, Marie-Thérèse, Clerigue, Montserrat, Cognat, Emmanuel, Coll, Nina, Collij, Lyduine E, Connely, Peter, Cordier, Elodie, Costes, Corine, Coulange, Camille, Courtemanche, Hélène, Creisson, Eric, Crinquette, Charlotte, Cuevas, Rosario, Cufi, Marie-Noëlle, Dardenne, Sophie, de Arriba, Maria, de Costa Luis, Casper, de Gier, Yvonne, de Verbizier Lonjon, Delphine, and Dekker, Veronique
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Male ,Adult ,metabolism [Brain] ,Positron-Emission Tomography ,diagnosis [Alzheimer Disease] ,diagnostic imaging [Cognitive Dysfunction] ,Humans ,metabolism [Amyloid beta-Peptides] ,ddc:610 ,Prospective Studies ,Disclosure ,General Medicine ,Aged - Abstract
ImportanceIndividuals who are amyloid-positive with subjective cognitive decline and clinical features increasing the likelihood of preclinical Alzheimer disease (SCD+) are at higher risk of developing dementia. Some individuals with SCD+ undergo amyloid-positron emission tomography (PET) as part of research studies and frequently wish to know their amyloid status; however, the disclosure of a positive amyloid-PET result might have psychological risks.ObjectiveTo assess the psychological outcomes of the amyloid-PET result disclosure in individuals with SCD+ and explore which variables are associated with a safer disclosure in individuals who are amyloid positive.Design, Setting, and ParticipantsThis prospective, multicenter study was conducted as part of The Amyloid Imaging to Prevent Alzheimer Disease Diagnostic and Patient Management Study (AMYPAD-DPMS) (recruitment period: from April 2018 to October 2020). The setting was 5 European memory clinics, and participants included patients with SCD+ who underwent amyloid-PET. Statistical analysis was performed from July to October 2022.ExposuresDisclosure of amyloid-PET result.Main Outcomes and MeasuresPsychological outcomes were defined as (1) disclosure related distress, assessed using the Impact of Event Scale–Revised (IES-R; scores of at least 33 indicate probable presence of posttraumatic stress disorder [PTSD]); and (2) anxiety and depression, assessed using the Hospital Anxiety and Depression scale (HADS; scores of at least 15 indicate probable presence of severe mood disorder symptoms).ResultsAfter disclosure, 27 patients with amyloid-positive SCD+ (median [IQR] age, 70 [66-74] years; gender: 14 men [52%]; median [IQR] education: 15 [13 to 17] years, median [IQR] Mini-Mental State Examination [MMSE] score, 29 [28 to 30]) had higher median (IQR) IES-R total score (10 [2 to 14] vs 0 [0 to 2]; P P P P P = .06) and Depression (–1.0 [–2.0 to 0.0] vs –1.0 [–3.0 to 0.0]; P = .46) deltas (score after disclosure – scores at baseline). In patients with amyloid-positive SCD+, despite the small sample size, higher education was associated with lower disclosure-related distress (ρ = –0.43; P = .02) whereas the presence of study partner was associated with higher disclosure-related distress (W = 7.5; P = .03). No participants with amyloid-positive SCD+ showed probable presence of PTSD or severe anxiety or depression symptoms at follow-up.Conclusions and RelevanceThe disclosure of a positive amyloid-PET result to patients with SCD+ was associated with a bigger psychological change, yet such change did not reach the threshold for clinical concern.
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- 2023
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22. Crosstalk between cilia and autophagy: implication for human diseases
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Manuela Morleo, Helena L.A. Vieira, Petra Pennekamp, Alessandro Palma, Liliana Bento-Lopes, Heymut Omran, Susana S. Lopes, Duarte C. Barral, Brunella Franco, Morleo, Manuela, Vieira, Helena L A, Pennekamp, Petra, Palma, Alessandro, Bento-Lopes, Liliana, Omran, Heymut, Lopes, Susana S, Barral, Duarte C, and Franco, Brunella
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Autophagy ,cilia ,human diseases ,lysosome ,macroautophagy ,mitochondria ,human disease ,Cell Biology ,Microtubules ,Ciliopathies ,Mitochondrial Proteins ,Humans ,Molecular Biology - Abstract
Macroautophagy/autophagy is a self-degradative process necessary for cells to maintain their energy balance during development and in response to nutrient deprivation. Autophagic processes are tightly regulated and have been found to be dysfunctional in several pathologies. Increasing experimental evidence points to the existence of an interplay between autophagy and cilia. Cilia are microtubule-based organelles protruding from the cell surface of mammalian cells that perform a variety of motile and sensory functions and, when dysfunctional, result in disorders known as ciliopathies. Indeed, selective autophagic degradation of ciliary proteins has been shown to control ciliogenesis and, conversely, cilia have been reported to control autophagy. Moreover, a growing number of players such as lysosomal and mitochondrial proteins are emerging as actors of the cilia-autophagy interplay. However, some of the published data on the cilia-autophagy axis are contradictory and indicate that we are just starting to understand the underlying molecular mechanisms. In this review, the current knowledge about this axis and challenges are discussed, as well as the implication for ciliopathies and autophagy-associated disorders.
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- 2023
23. Measurement of CP asymmetries in D(s)+→ηπ+ and D(s)+→η′π+ decays
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Aaij R., Abdelmotteleb A. S. W., Abellan Beteta C., Abudinen F., Ackernley T., Adeva B., Adinolfi M., Afsharnia H., Agapopoulou C., Aidala C. A., Aiola S., Ajaltouni Z., Akar S., Akiba K., Albrecht J., Alessio F., Alexander M., Alfonso Albero A., Aliouche Z., Alvarez Cartelle P., Amato S., Amey J. L., Amhis Y., An L., Anderlini L., Andersson M., Andreianov A., Andreotti M., Ao D., Archilli F., Artamonov A., Artuso M., Arzymatov K., Aslanides E., Atzeni M., Audurier B., Bachmann S., Bachmayer M., Back J. J., Bailly-reyre A., Baladron Rodriguez P., Balagura V., Baldini W., Baptista de Souza Leite J., Barbetti M., Barlow R. J., Barsuk S., Barter W., Bartolini M., Baryshnikov F., Basels J. M., Bassi G., Batsukh B., Battig A., Bay A., Beck A., Becker M., Bedeschi F., Bediaga I. B., Beiter A., Belavin V., Belin S., Bellee V., Belous K., Belov I., Belyaev I., Bencivenni G., Ben-Haim E., Berezhnoy A., Bernet R., Berninghoff D., Bernstein H. 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- Subjects
CP Violation ,Hadron-Hadron Scattering ,Charm Physic ,Flavour Physic - Abstract
Searches for CP violation in the decays D(s)+→ηπ+ and D(s)+→η′π+ are performed using pp collision data corresponding to 6 fb−1 of integrated luminosity collected by the LHCb experiment. The calibration channels D(s)+→ϕπ+ are used to remove production and detection asymmetries. The resulting CP-violating asymmetries areACP=(D+→ηπ+)=(0.34±0.66±0.16±0.05)%,ACP=(Ds+→ηπ+)=(0.32±0.51±0.12)%,ACP=(D+→η′π+)=(0.49±0.18±0.06±0.05)%,ACP=(Ds+→η′π+)=(0.01±0.12±0.08)%, where the first uncertainty is statistical, the second is systematic and the third, relevant for the D+ channels, is due to the uncertainty on ACP= (D+→ ϕπ+). These measurements, currently the most precise for three of the four channels considered, are consistent with the absence of CP violation. A combination of these results with previous LHCb measurements is presented. [Figure not available: see fulltext.].
- Published
- 2023
24. Geographic patterns of tree dispersal modes in Amazonia and their ecological correlates
- Author
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A., Vos, Vincent Antoine, Zent, Stanford, Zent, Egleé L., Noronha, Janaína Costa, Albuquerque, Bianca Weiss, Cano, Angela, Carrero Márquez, Yrma Andreina, Costa, Janaina Barbosa Pedrosa, Flores, Bernardo Monteiro, Galbraith, David, Holmgren, Milena, Kalamandeen, Michelle, Nascimento, Marcelo Trindade, Oliveira, Alexandre A., Ramirez-Angulo, Hirma, Rocha, Maira, Scudeller, Veridiana Vizoni, Sierra, Rodrigo, Tirado, Milton, van der Heijden, Geertje, Vilanova Torre, Emilio, Vriesendorp, Corine, Pombo, Maihyra Marina, Ahuite Reategui, Manuel Augusto, Baider, Cláudia, Balslev, Henrik, Cárdenas, Sasha, Casas, Luisa Fernanda, Farfan-Rios, William, Ferreira, Cid, Linares-Palomino, Reynaldo, Mendoza, Casimiro, Mesones, Italo, Torres-Lezama, Armando, Urrego Giraldo, Ligia Estela, Villarroel, Daniel, Zagt, Roderick, Parada, Germaine Alexander, Alexiades, Miguel N., de Oliveira, Edmar Almeida, Garcia-Cabrera, Karina, Hernandez, Lionel, Palacios Cuenca, Walter, Pansini, Susamar, Pauletto, Daniela, Ramirez Arevalo, Freddy, Sampaio, Adeilza Felipe, Valderrama Sandoval, Elvis H., Valenzuela Gamarra, Luis, ter Steege, Hans, DIEGO F. CORREA, UNIVERSIDAD DE LOS ANDES, PABLO R. STEVENSON, UNIVERSIDAD DE LOS ANDES, MARIA NATALIA UMAÑA, UNIVERSITY OF MICHIGAN, LUIZ DE SOUZA COELHO, INSTITUTO NACIONAL DE PESQUISAS DA AMAZÔNIA, DIÓGENES DE ANDRADE LIMA FILHO, INSTITUTO NACIONAL DE PESQUISAS DA AMAZÔNIA, RAFAEL P. SALOMÃO, UNIVERSIDADE FEDERAL RURAL DA AMAZÔNIA, IÊDA LEÃO DO AMARAL, INSTITUTO NACIONAL DE PESQUISAS DA AMAZÔNIA, FLORIAN WITTMANN, KARLSRUHE INSTITUTE OF TECHNOLOGY, FRANCISCA DIONÍZIA DE ALMEIDA MATOS, INSTITUTO NACIONAL DE PESQUISAS DA AMAZÔNIA, CAROLINA VOLKMER DE CASTILHO, CPAF-RR, OLIVER L. PHILLIPS, UNIVERSITY OF LEEDS, JUAN ERNESTO GUEVARA, UNIVERSIDAD DE LAS AMÉRICAS, MARCELO DE JESUS VEIGA CARIM, INSTITUTO DE PESQUISAS CIENTÍFICAS E TECNOLÓGICAS DO AMAPÁ, WILLIAM E. 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PITMAN, THE FIELD MUSEUM, ABEL MONTEAGUDO MENDOZA, UNIVERSIDAD NACIONAL DE SAN ANTONIO ABAD DEL CUSCO, JOSÉ FERREIRA RAMOS, INSTITUTO NACIONAL DE PESQUISAS DA AMAZÔNIA, BRUNO GARCIA LUIZE, UNIVERSIDADE ESTADUAL DE CAMPINAS, EVLYN MÁRCIA MORAES DE LEÃO NOVO, INSTITUTO NACIONAL DE PESQUISAS ESPACIAIS, PERCY NÚÑEZ VARGAS, UNIVERSIDAD NACIONAL DE SAN ANTONIO ABAD DEL CUSCO, THIAGO SANNA FREIRE SILVA, UNIVERSITY OF STIRLING, EDUARDO MARTINS VENTICINQUE, UNIVERSIDADE FEDERAL DO RIO GRANDE DO NORTE, ANGELO GILBERTO MANZATTO, UNIVERSIDADE FEDERAL DE RONDÔNIA, NEIDIANE FARIAS COSTA REIS, UNIVERSIDADE FEDERAL DE RONDÔNIA, JOHN W. TERBORGH, UNIVERSITY OF FLORIDA, KATIA REGINA CASULA, UNIVERSIDADE FEDERAL DE RONDÔNIA, EURIDICE N. HONORIO CORONADO, INSTITUTO DE INVESTIGACIONES DE LA AMAZONÍA PERUANA, JUAN CARLOS MONTERO, INSTITUTO NACIONAL DE PESQUISAS DA AMAZÔNIA, JOCHEN SCHÖNGART, INSTITUTO NACIONAL DE PESQUISAS DA AMAZÔNIA, DAIRON CÁRDENAS LÓPEZ, INSTITUTO SINCHI, FLÁVIA R. C. COSTA, INSTITUTO NACIONAL DE PESQUISAS DA AMAZÔNIA, ADRIANO COSTA QUARESMA, INSTITUTO NACIONAL DE PESQUISAS DA AMAZÔNIA, CHARLES EUGENE ZARTMAN, INSTITUTO NACIONAL DE PESQUISAS DA AMAZÔNIA, TIMOTHY J. KILLEEN, AGTECA-AMAZONICA, BEATRIZ S. MARIMON, UNIVERSIDADE DO ESTADO DE MATO GROSSO, BEN HUR MARIMON-JUNIOR, UNIVERSIDADE DO ESTADO DE MATO GROSSO, RODOLFO VASQUEZ, JARDÍN BOTÁNICO DE MISSOURI, BONIFACIO MOSTACEDO, UNIVERSIDAD AUTÓNOMA GABRIEL RENÉ MORENO, LAYON O. DEMARCHI, INSTITUTO NACIONAL DE PESQUISAS DA AMAZÔNIA, TED R. FELDPAUSCH, UNIVERSITY OF LEEDS, RAFAEL L. ASSIS, UNIVERSITY OF OSLO, CHRISTOPHER BARALOTO, FLORIDA INTERNATIONAL UNIVERSITY, JULIEN ENGEL, UNIVERSITÉ DE MONTPELLIER, PASCAL PETRONELLI, CENTRE DE COOPÉRATION INTERNATIONALE EN RECHERCHE AGRONOMIQUE POUR LE DÉVELOPPEMENT, HERNÁN CASTELLANOS, UNIVERSIDAD NACIONAL EXPERIMENTAL DE GUAYANA, MARCELO BRILHANTE DE MEDEIROS, Cenargen, MARCELO FRAGOMENI SIMON, Cenargen, ANA ANDRADE, INSTITUTO NACIONAL DE PESQUISAS DA AMAZÔNIA, JOSÉ LUÍS CAMARGO, INSTITUTO NACIONAL DE PESQUISAS DA AMAZÔNIA, SUSAN G. W. LAURANCE, JAMES COOK UNIVERSITY, WILLIAM F. LAURANCE, JAMES COOK UNIVERSITY, LORENA MANIGUAJE RINCÓN, INSTITUTO NACIONAL DE PESQUISAS DA AMAZÔNIA, JULIANA SCHIETTI, INSTITUTO NACIONAL DE PESQUISAS DA AMAZÔNIA, THAIANE R. 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MOGOLLÓN, ENDANGERED SPECIES COALITION, ALEJANDRO ARAUJO-MURAKAMI, UNIVERSIDAD AUTÓNOMA GABRIEL RENE MORENO, LEANDRO VALLE FERREIRA, MUSEU PARAENSE EMÍLIO GOELDI, JOSÉ RAFAEL LOZADA, UNIVERSIDAD DE LOS ANDES, JAMES A. COMISKEY, NATIONAL PARK SERVICE, JOSÉ JULIO DE TOLEDO, UNIVERSIDADE FEDERAL DO AMAPÁ, GABRIEL DAMASCO, UNIVERSITY OF GOTHENBURG, NÁLLARETT DÁVILA, UNIVERSIDADE ESTADUAL DE CAMPINAS, ROOSEVELT GARCÍA-VILLACORTA, CENTRO DE INNOVACIÓN CIENTÍFICA AMAZÓNICA, ALINE LOPES, UNIVERSIDADE DE BRASILIA, ALBERTO VICENTINI, INSTITUTO NACIONAL DE PESQUISAS DA AMAZÔNIA, FREDDIE C. DRAPER, UNIVERSITY OF LIVERPOOL, NICOLÁS CASTAÑO ARBOLEDA, INSTITUTO SINCHI, FERNANDO CORNEJO VALVERDE, ANDES TO AMAZON BIODIVERSITY PROGRAM, ALFONSO ALONSO, SMITHSONIAN CONSERVATION BIOLOGY INSTITUTE, FRANCISCO DALLMEIER, SMITHSONIAN CONSERVATION BIOLOGY INSTITUTE, VITOR H. F. GOMES, CENTRO UNIVERSITÁRIO DO PARÁ, DAVID NEILL, UNIVERSIDAD ESTATAL AMAZÓNICA, DANIEL P. P. 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BAKER, UNIVERSITY OF LEEDS, DOUG DALY, NEW YORK BOTANICAL GARDEN, ISAU HUAMANTUPA-CHUQUIMACO, UNIVERSIDAD NACIONAL AMAZÓNICA DE MADRE DE DIOS, WILLIAM MILLIKEN, ROYAL BOTANIC GARDENS, TOBY PENNINGTON, UNIVERSITY OF EXETER, MARCOS RÍOS PAREDES, SERVICIOS DE BIODIVERSIDAD EIRL, PARDO MOLINA, UNIVERSIDAD AUTÓNOMA DEL BENI JOSÉ BALLIVIÁN, ALFREDO FUENTES, UNIVERSIDAD MAYOR DE SAN ANDRÉS, BENTE KLITGAARD, ROYAL BOTANIC GARDENS, JOSÉ LUIS MARCELO PEÑA, UNIVERSIDAD NACIONAL DE JAÉN, CARLOS A. PERES, UNIVERSITY OF EAST ANGLIA, MILES R. SILMAN, WAKE FOREST UNIVERSITY, J. SEBASTIÁN TELLO, MISSOURI BOTANICAL GARDEN, WEGLIANE CAMPELO, UNIVERSIDADE FEDERAL DO AMAPÁ, JEROME CHAVE, UNIVERSITÉ PAUL SABATIER, ANTHONY DI FIORE, UNIVERSITY OF TEXAS AT AUSTIN, RENATO RICHARD HILÁRIO, UNIVERSIDADE FEDERAL DO AMAPÁ, JUAN FERNANDO PHILLIPS, FUNDACIÓN PUERTO RASTROJO, GONZALO RIVAS-TORRES, UNIVERSIDAD SAN FRANCISCO DE QUITO, TINDE R. VAN ANDEL, NATURALIS BIODIVERSITY CENTER, PATRICIO VON HILDEBRAND, FUNDACIÓN ESTACIÓN DE BIOLOGÍA, LUCIANA DE OLIVEIRA PEREIRA, UNIVERSITY OF EXETER, EDELCILIO MARQUES BARBOSA, INSTITUTO NACIONAL DE PESQUISAS DA AMAZÔNIA, FLÁVIA RODRIGUES BARBOSA, UNIVERSIDADE FEDERAL DO MATO GROSSO, LUIZ CARLOS DE MATOS BONATES, INSTITUTO NACIONAL DE PESQUISAS DA AMAZÔNIA, RAINIELLEN DE SÁ CARPANEDO, UNIVERSIDADE FEDERAL DO MATO GROSSO, HILDA PAULETTE DÁVILA DOZA, SERVICIOS DE BIODIVERSIDAD EIRL, RICARDO ZÁRATE GÓMEZ, INSTITUTO DE INVESTIGACIONES DE LA AMAZONÍA PERUANA, THERANY GONZALES, ACEER FOUNDATION, GEORGE PEPE GALLARDO GONZALES, SERVICIOS DE BIODIVERSIDAD EIRL, BRUCE HOFFMAN, AMAZON CONSERVATION TEAM, ANDRÉ BRAGA JUNQUEIRA, UNIVERSITAT AUTÒNOMA DE BARCELONA, YADVINDER MALHI, UNIVERSITY OF OXFORD, IRES PAULA DE ANDRADE MIRANDA, INSTITUTO NACIONAL DE PESQUISAS DA AMAZÔNIA, LINDER FELIPE MOZOMBITE PINTO, SERVICIOS DE BIODIVERSIDAD EIRL, ADRIANA PRIETO, UNIVERSIDAD NACIONAL DE COLOMBIA, DOMINGOS DE JESUS RODRIGUES, UNIVERSIDADE FEDERAL DO MATO GROSSO, AGUSTÍN RUDAS, UNIVERSIDAD NACIONAL DE COLOMBIA, ADEMIR ROBERTO RUSCHEL, CPATU, NATALINO SILVA, UNIVERSIDADE FEDERAL RURAL DA AMAZÔNIA, CÉSAR I. A. VELA, UNIVERSIDAD NACIONAL DE SAN ANTONIO ABAD DEL CUSCO, VINCENT ANTOINE VOS, UNIVERSIDAD AUTÓNOMA DEL BENI JOSÉ BALLIVIÁN, STANFORD ZENT, INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTÍFICAS, EGLEÉ L. ZENT, INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTÍFICAS, JANAÍNA COSTA NORONHA, UNIVERSIDADE FEDERAL DO MATO GROSSO, BIANCA WEISS ALBUQUERQUE, INSTITUTO NACIONAL DE PESQUISAS DA AMAZÔNIA, ANGELA CANO, UNIVERSIDAD DE LOS ANDES, YRMA ANDREINA CARRERO MÁRQUEZ, UNIVERSIDAD DE LOS ANDES, JANAINA BARBOSA PEDROSA COSTA, BERNARDO MONTEIRO FLORES, UNIVERSIDADE FEDERAL DE SANTA CATARINA, DAVID GALBRAITH, UNIVERSITY OF LEEDS, MILENA HOLMGREN, WAGENINGEN UNIVERSITY & RESEARCH, MICHELLE KALAMANDEEN, MCMASTER UNIVERSITY, MARCELO TRINDADE NASCIMENTO, UNIVERSIDADE ESTADUAL DO NORTE FLUMINENSE, ALEXANDRE A. OLIVEIRA, UNIVERSIDADE DE SAO PAULO, HIRMA RAMIREZ-ANGULO, UNIVERSIDAD DE LOS ANDES, MAIRA ROCHA, INSTITUTO NACIONAL DE PESQUISAS DA AMAZÔNIA, VERIDIANA VIZONI SCUDELLER, UNIVERSIDADE FEDERAL DO AMAZONAS, RODRIGO SIERRA, GEOIS, MILTON TIRADO, GEOIS, GEERTJE VAN DER HEIJDEN, UNIVERSITY OF NOTTINGHAM, EMILIO VILANOVA TORRE, UNIVERSIDAD DE LOS ANDES, CORINE VRIESENDORP, THE FIELD MUSEUM, MAIHYRA MARINA POMBO, INSTITUTO NACIONAL DE PESQUISAS DA AMAZÔNIA, MANUEL AUGUSTO AHUITE REATEGUI, PLUSPRETOL, CLÁUDIA BAIDER, UNIVERSIDADE DE SAO PAULO, HENRIK BALSLEV, AARHUS UNIVERSITY, SASHA CÁRDENAS, UNIVERSIDAD DE LOS ANDES, LUISA FERNANDA CASAS, UNIVERSIDAD DE LOS ANDES, WILLIAM FARFAN-RIOS, UNIVERSIDAD NACIONAL DE SAN ANTONIO ABAD DEL CUSCO, CID FERREIRA, INSTITUTO NACIONAL DE PESQUISAS DA AMAZÔNIA, REYNALDO LINARES-PALOMINO, SMITHSONIAN CONSERVATION BIOLOGY INSTITUTE, CASIMIRO MENDOZA, UNIVERSIDAD MAYOR DE SAN SIMON, ITALO MESONES, UNIVERSITY OF CALIFORNIA, ARMANDO TORRES-LEZAMA, UNIVERSIDAD DE LOS ANDES, LIGIA ESTELA URREGO GIRALDO, UNIVERSIDAD NACIONAL DE COLOMBIA, DANIEL VILLARROEL, UNIVERSIDAD AUTÓNOMA GABRIEL RENE MORENO, RODERICK ZAGT, TROPENBOS INTERNATIONAL, GERMAINE ALEXANDER PARADA, UNIVERSIDAD AUTÓNOMA GABRIEL RENE MORENO, MIGUEL N. ALEXIADES, UNIVERSITY OF KENT, EDMAR ALMEIDA DE OLIVEIRA, UNIVERSIDADE DO ESTADO DE MATO GROSSO, KARINA GARCIA-CABRERA, WAKE FOREST UNIVERSITY, LIONEL HERNANDEZ, UNIVERSIDAD NACIONAL EXPERIMENTAL DE GUAYANA, WALTER PALACIOS CUENCA, UNIVERSIDAD TÉCNICA DEL NORTE, SUSAMAR PANSINI, UNIVERSIDADE FEDERAL DE RONDÔNIA, DANIELA PAULETTO, UNIVERSIDADE FEDERAL DO OESTE DO PARÁ, FREDDY RAMIREZ AREVALO, UNIVERSIDAD NACIONAL DE LA AMAZONIA PERUANA, ADEILZA FELIPE SAMPAIO, UNIVERSIDADE FEDERAL DE RONDÔNIA, ELVIS H. VALDERRAMA SANDOVAL, UNIVERSIDAD NACIONAL DE LA AMAZONIA PERUANA, LUIS VALENZUELA GAMARRA, JARDÍN BOTÁNICO DE MISSOURI, HANS TER STEEGE, NATURALIS BIODIVERSITY CENTER., University of St Andrews. Geography & Sustainable Development, University of St Andrews. School of Geography & Sustainable Development, Universidad de los Andes [Bogota] (UNIANDES), University of Michigan [Ann Arbor], University of Michigan System, Instituto Nacional de Pesquisas da Amazônia (INPA), Universidade Federal Rural da Amazônia (UFRA), Botanique et Modélisation de l'Architecture des Plantes et des Végétations (UMR AMAP), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université de Montpellier (UM), Missouri Botanical Garden, and Naturalis Biodiversity Center [Leiden]
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Geography & travel ,[SDV.BID.SPT]Life Sciences [q-bio]/Biodiversity/Systematics, Phylogenetics and taxonomy ,[SDV.EE.ECO]Life Sciences [q-bio]/Ecology, environment/Ecosystems ,Florestas inundadas ,flooded forests ,terra-firme forests ,Ecology, Evolution, Behavior and Systematics ,ddc:910 ,Disperser‐availability hypothesis ,Global and Planetary Change ,Resource‐availability hypothesis ,Ecology ,anemochory ,Terra‐firme forests ,resource-availability hypothesis ,DAS ,[SDV.BV.BOT]Life Sciences [q-bio]/Vegetal Biology/Botanics ,PE&RC ,dispersal agents ,Biosystematiek ,endozoochory ,Floresta de terra firme ,MCP ,Floresta Pluvial Tropical ,Wildlife Ecology and Conservation ,synzoochory ,Biosystematics ,hydrochory ,ARBORIZAÇÃO ,Rain forests ,[SDE.BE]Environmental Sciences/Biodiversity and Ecology ,disperser-availability hypothesis ,Amazonian rain forests - Abstract
DFC acknowledges financial support from the Colombian institution Departamento Administrativo de Ciencia, Tecnología e Innovación COLCIENCIAS (Convocatoria 529 para estudios de doctorado en el exterior). PRS acknowledges the Faculty of Sciences, Universidad de los Andes, for financial support (INV-2021-128-2268). Aim : To investigate the geographic patterns and ecological correlates in the geographic distribution of the most common tree dispersal modes in Amazonia (endozoochory, synzoochory, anemochory and hydrochory). We examined if the proportional abundance of these dispersal modes could be explained by the availability of dispersal agents (disperser‐availability hypothesis) and/or the availability of resources for constructing zoochorous fruits (resource‐availability hypothesis). Time period : Tree‐inventory plots established between 1934 and 2019. Major taxa studied : Trees with a diameter at breast height (DBH) ≥ 9.55 cm. Location : Amazonia, here defined as the lowland rain forests of the Amazon River basin and the Guiana Shield. Methods : We assigned dispersal modes to a total of 5433 species and morphospecies within 1877 tree‐inventory plots across terra‐firme, seasonally flooded, and permanently flooded forests. We investigated geographic patterns in the proportional abundance of dispersal modes. We performed an abundance‐weighted mean pairwise distance (MPD) test and fit generalized linear models (GLMs) to explain the geographic distribution of dispersal modes. Results : Anemochory was significantly, positively associated with mean annual wind speed, and hydrochory was significantly higher in flooded forests. Dispersal modes did not consistently show significant associations with the availability of resources for constructing zoochorous fruits. A lower dissimilarity in dispersal modes, resulting from a higher dominance of endozoochory, occurred in terra‐firme forests (excluding podzols) compared to flooded forests. Main conclusions : The disperser‐availability hypothesis was well supported for abiotic dispersal modes (anemochory and hydrochory). The availability of resources for constructing zoochorous fruits seems an unlikely explanation for the distribution of dispersal modes in Amazonia. The association between frugivores and the proportional abundance of zoochory requires further research, as tree recruitment not only depends on dispersal vectors but also on conditions that favour or limit seedling recruitment across forest types. Publisher PDF
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25. A Revision of Polymeric Nanoparticles as a Strategy to Improve the Biological Activity of Melatonin
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Pablo Igor Ribeiro, Franco, José Rodrigues, do Carmo Neto, Viviane Lopes, Rocha, Juliana Reis, Machado, Andre Correa, Amaral, and Marina Pacheco, Miguel
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Pharmacology ,Drug Discovery ,Organic Chemistry ,Molecular Medicine ,Biochemistry - Abstract
Abstract: Drug delivery systems based on nanotechnology exhibit a number of advantages over traditional pharmacological formulations. Polymeric nanoparticles are commonly used as delivery systems and consist of synthetic or natural polymers that protect drugs from degradation in physiological environments. In this context, indolamine melatonin has been associated with several biological functions, including antioxidant, antitumor, immunoregulatory, neuroprotective, and cardioprotective effects. However, its availability, half-life, and absorption depend upon the route of administration, and this can limit its therapeutic potential. An alternative is the use of polymeric nanoparticle formulations associated with melatonin to increase its bioavailability and therapeutic dose at sites of interest. Thus, the objective of this review is to provide a general and concise approach to the therapeutic association between melatonin and polymeric nanoparticles applied to different biological disorders and to also highlight its advantages and potential applications compared to those of the typical drug formulations that are available.
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- 2023
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26. The center and invariants of standard filiform Lie algebras
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de Jesus, Vanderlei Lopes and Schneider, Csaba
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Algebra and Number Theory ,Rings and Algebras (math.RA) ,FOS: Mathematics ,17B35, 17B30, 16U70, 16W22, 17-08 ,Mathematics - Rings and Algebras ,Commutative Algebra (math.AC) ,Mathematics - Commutative Algebra - Abstract
This paper describes the centers of the universal enveloping algebras and the invariant rings of the standard filiform Lie algebras over fields of characteristic zero and also over large enough prime characteristic. We determine explicit generators for the quotient fields and also a compact form for the generators for the invariants rings. We prove several combinatorial results concerning the Hilbert series of these algebras.
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- 2023
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27. Body composition, lipid profile and clinical parameters are predictors of prognosis in patients with heart failure: Two-year follow-up
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Eduardo Paixão da Silva, Regina Ranielly dos Santos Avelino, Rosiane Viana Zuza Diniz, Niethia Regina Dantas de Lira, Salomão Israel Monteiro Lourenço Queiroz, Márcia Marília Gomes Dantas Lopes, and Karine Cavalcanti Maurício Sena-Evangelista
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Nutrition and Dietetics ,Endocrinology, Diabetes and Metabolism - Published
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28. Selection of lima bean accessions for fresh and dry production
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Loren R. Damas, Priscila A. Barroso, Wilson V. de Assunção Neto, Angela C. de A. Lopes, José V. da Silva Junior, Regina L. F. Gomes, and Artur M. Medeiros
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Environmental Engineering ,breeding programs ,variedades crioulas ,Phaseolus lunatus L ,Agricultural and Biological Sciences (miscellaneous) ,Agronomy and Crop Science ,heirloom varieties ,programas de melhoramento - Abstract
The selection of lima bean accessions in the fresh and dry stages is an excellent tool to increase crop yield in Brazil and ensure a source of vegetable protein for the population. Principal component analysis and nonparametric indices can be used to identify promising accessions based on the desired agronomic variables. The aim of the present study was to select accessions from traditional lima bean varieties in the fresh and dry stages using principal component analysis and nonparametric selection indices. The experiment consisted of a randomized block design, evaluating 13 treatments in four replicates. The experimental plot contained 20 plants in its study area. The first two principal components for the two stages explained more than 80% of the variation found among the accessions. The Mulamba & Mock and Genotype-Ideotype selection indices were efficient in classifying promising varieties for breeding programs. The UFPI 1111 accession can be used in fresh lima bean production, and its UFPI 1248 and 1294 counterparts in lima bean breeding programs. RESUMO A seleção de acessos de feijão-fava nos estádios verde e seco é uma excelente ferramenta para aumentar a produtividade da cultura no país e garantir uma fonte de proteína vegetal para a população. O uso de componentes principais e índices de seleção não-paramétricos podem ser utilizados para identificar acessos promissores com base em características agronômicas desejáveis. O objetivo do presente estudo foi selecionar acessos de variedades crioulas de feijão-fava nos estádios frescos e secos utilizando componentes principais e índices de seleção não paramétricos. O experimento foi disposto em delineamento em blocos casualizados, sendo avaliados 13 tratamentos em quatro repetições. A parcela experimental conteve 20 plantas em sua área útil. Os dois primeiros componentes principais, para os dois estádios, explicaram mais de 80% da variação encontrada entre os acessos. Os índices de seleção de Mulamba & Mock e Genótipo-Ideótipo foram eficientes na classificação de variedades promissoras para programas de melhoramento. O acesso UFPI 1111 pode ser direcionado para a produção de fava verde, e os acessos UFPI 1248 e UFPI 1294 podem ser utilizados para programas de melhoramento de fava seca.
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29. The C-terminal mutation beyond the catalytic site of brown spider phospholipase D significantly impacts its biological activities
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Laís Cardoso Cunha, Lucas Passos Barreto, Veronica Silva Valadares, Camila Franco Batista Oliveira, Larissa Vuitika, Maura Páscoa Vilela, Elio A. Cino, Adolfo Henrique de Moraes Silva, Ronaldo A.P. Nagem, Carlos Chávez-Olórtegui, Camila Dias-Lopes, Franck Molina, and Liza Felicori
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General Medicine ,Biochemistry - Published
- 2023
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30. Outlining the Molecules Tested In Vivo for Chagas Disease, Malaria, and Schistosomiasis Over the Last Six Years - A Literature Review Focused on New Synthetic Drug Identities and Repurposing Strategies
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Ana Cristina Lima Leite, Vanessa Gouveia de Melo Silva, Juliana Maria da Conceição, Carla Cauanny Vieira Costa Silva, Amanda Calazans Leal, Daniel Lopes Araújo, Janine Siqueira Nunes, Elineide Tayse Noberto da Silva, Anderson José Firmino Santos da Silva, and Mabilly Cox Holanda de Barros Dias
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Pharmacology ,Drug Discovery ,Organic Chemistry ,Molecular Medicine ,Biochemistry - Abstract
Background: COVID-19 disrupted NTD programs in 60% of countries, impairing public health goals. Thus, boosting NTD's research knowledge is demanding, and in vivo screening of candidates allows for the prospect of promising options based on their overall profile. Objective: In this work, we highlighted the relevant research done between 2015-2021 in the fields of synthetic and repurposed drugs that were tested in vivo for Chagas disease, malaria, and schistosomiasis. Methods: MEDLINE, PUBMED, CAPES PERIODIC, and ELSEVIER databases were used for a comprehensive literature review of the last 6 years of research on each area/disease. Results: Overall, research focused on nitro heterocyclic, aromatic nitro, nucleoside, and metal-based scaffolds for analogue-based drug generation. Repurposing was widely assessed, mainly with heterocyclic drugs, their analogues, and in combinations with current treatments. Several drug targets were aimed for Chagas treatment, specific ones such as iron superoxide dismutase, and more general ones, such as mitochondrial dysfunction. For malaria, hemozoin is still popular, and for schistosomiasis, more general structural damage and/or reproduction impairment were aimed at in vitro analysis of the mechanism of action. Conclusion: Latest in vivo results outlined trends for each disease - for Chagas Disease, heterocyclics as thiazoles were successfully explored; for Malaria, quinoline derivatives are still relevant, and for schistosomiasis, repurposed drugs from different classes outstood in comparison to synthetic compounds. This study uprises the continuous development of Chagas disease, malaria, and schistosomiasis drugs, providing researchers with tools and information to address such unmet therapeutic needs.
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- 2023
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31. Assessment of functional mobility and gait during a timed up and go test in adults with total blindness
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Rodolfo Borges Parreira, Jamile Benite Palma Lopes, Lorraine Barbosa Cordeiro, Manuela Galli, and Claudia Santos Oliveira
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Complementary and Manual Therapy ,Complementary and alternative medicine ,Rehabilitation ,Physical Therapy, Sports Therapy and Rehabilitation - Published
- 2023
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32. Optimized Artificial Intelligence for Enhanced Ectasia Detection Using Scheimpflug-Based Corneal Tomography and Biomechanical Data
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Renato Ambrósio, Aydano P. Machado, Edileuza Leão, João Marcelo G. Lyra, Marcella Q. Salomão, Louise G. Pellegrino Esporcatte, João B.R. da Fonseca Filho, Erica Ferreira-Meneses, Nelson B. Sena, Jorge S. Haddad, Alexandre Costa Neto, Gildasio Castelo de Almeida, Cynthia J. Roberts, Ahmed Elsheikh, Riccardo Vinciguerra, Paolo Vinciguerra, Jens Bühren, Thomas Kohnen, Guy M. Kezirian, Farhad Hafezi, Nikki L. Hafezi, Emilio A. Torres-Netto, Nanji Lu, David Sung Yong Kang, Omid Kermani, Shizuka Koh, Prema Padmanabhan, Suphi Taneri, William Trattler, Luca Gualdi, José Salgado-Borges, Fernando Faria-Correia, Elias Flockerzi, Berthold Seitz, Vishal Jhanji, Tommy C.Y. Chan, Pedro Manuel Baptista, Dan Z. Reinstein, Timothy J. Archer, Karolinne M. Rocha, George O. Waring, Ronald R. Krueger, William J. Dupps, Ramin Khoramnia, Hassan Hashemi, Soheila Asgari, Hamed Momeni-Moghaddam, Siamak Zarei-Ghanavati, Rohit Shetty, Pooja Khamar, Michael W. Belin, and Bernardo T. Lopes
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Ophthalmology ,Human medicine - Abstract
center dot PURPOSE: To optimize artificial intelligence (AI) algo-rithms to integrate Scheimpflug-based corneal tomogra-phy and biomechanics to enhance ectasia detection.center dot DESIGN: Multicenter cross-sectional case-control ret-rospective study.center dot METHODS: A total of 3886 unoperated eyes from 3412 patients had Pentacam and Corvis ST (Oculus Op-tikgerate GmbH) examinations. The database included 1 eye randomly selected from 1680 normal patients (N) and from 1181 "bilateral" keratoconus (KC) patients, along with 551 normal topography eyes from patients with very asymmetric ectasia (VAE-NT), and their 474 unoperated ectatic (VAE-E) eyes. The current TBIv1 (tomographic-biomechanical index) was tested, and an optimized AI algorithm was developed for augmenting accuracy.center dot RESULTS: The area under the receiver operating char-acteristic curve (AUC) of the TBIv1 for discriminating clinical ectasia (KC and VAE-E) was 0.999 (98.5% sen-sitivity; 98.6% specificity [cutoff: 0.5]), and for VAE-NT, 0.899 (76% sensitivity; 89.1% specificity [cutoff: 0.29]). A novel random forest algorithm (TBIv2), devel-oped with 18 features in 156 trees using 10-fold cross -validation, had a significantly higher AUC (0.945; De -Long, P < .0001) for detecting VAE-NT (84.4% sen-sitivity and 90.1% specificity; cutoff: 0.43; DeLong, P < .0001) and a similar AUC for clinical ectasia (0.999; DeLong, P = .818; 98.7% sensitivity; 99.2% specificity [cutoff: 0.8]). Considering all cases, the TBIv2 had a higher AUC (0.985) than TBIv1 (0.974; DeLong, P < .0001).center dot CONCLUSIONS: AI optimization to integrate Scheimpflug-based corneal tomography and biome-chanical assessments augments accuracy for ectasia detection, characterizing ectasia susceptibility in the diverse VAE-NT group. Some patients with VAE may have true unilateral ectasia. Machine learning consider-ing additional data, including epithelial thickness or other parameters from multimodal refractive imaging, will con-tinuously enhance accuracy. NOTE: Publication of this article is sponsored by the American Ophthalmological Society. (Am J Ophthalmol 2023;251: 126-142. (c) 2023 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license ( http://creativecommons.org/licenses/by/4.0/ ))
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33. Neuroimaging findings in paediatric patients with sickle cell disease
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V. Sousa Abreu, S. Xavier, M. Santos, R. Lopes da Silva, P. Kjöllerström, and C. Conceição
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Radiology, Nuclear Medicine and imaging ,General Medicine - Published
- 2023
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34. Validity and reliability of the short form brief pain inventory in older adults with nociceptive, neuropathic and nociplastic pain
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Ana Carolina Lopes Ferreira, Daniele Sirineu Pereira, Silvia Lanziotti Azevedo da Silva, Guilherme Almeida Carvalho, and Leani Souza Máximo Pereira
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Gerontology - Published
- 2023
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35. Behavioral, Sociodemographic, and Sleep Correlates of Symptoms of Depression amongst Older Brazilian Females According to Age: A Cross- Sectional Network Analysis
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Lucimere Bohn, Pedro Pugliesi Abdalla, Sitong Chen, Elzier Sampaio de Queiroz Neto, Dalmo Roberto Lopes Machado, Jorge Mota, and Clarice Martins Lucena
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Pulmonary and Respiratory Medicine ,Pediatrics, Perinatology and Child Health - Abstract
Background: Examining the interrelationships between symptoms of depression and sociodemographic and behavioral correlates is challengeful using traditional regression analysis. Objective: to identify the sociodemographic, movement behaviors, and sleep correlates that contribute the most to symptoms of depression in Brazilian older females, using a network analysis approach. Methods: This cross-sectional study analyzed 1019 older females from Brazil. Data (sociodemographic, height (meters), weight (kilograms), symptoms of depression, physical activity, sleep) were self-reported via phone calls. The relationships between symptoms of depression and their correlates were assessed using the Network Analysis (qgraph package of the Rstudio) for entire sample and age groups (60-69; 70-79 and 80+ years old). Results: 60-69 and 70-79 groups have more weekly home exits, with aging “single, widowed or divorced” was progressively higher, and “married or stable union” and Overweight/obesity were progressively fewer (p < 0.05). 60-69 have more education years and fewest medicaments use. Sleep compliance (for the entire sample), body mass index (for the 60-69), compliance with moderate to vigorous physical activity (for the 70-79), and educational level (for 80+) were the variables with the highest expected influence values (p < 0.05) on symptoms of depression (1.370; 1.388; 1.129; and 1.354, respectively). Conclusion: Symptoms of depression vary throughout the aging process and thus determine that intervention strategies encompass these specific factors according to each age group. Poor sleep behavior has a strong positive association with symptoms of depression. This result highlights that health professionals must be aware of the importance of sleep to mitigate the worsening of depression among older Brazilian females.
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36. Neurocysticercosis: a contemporary presentation of the neuroimaging main stages
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Mariana Lopes, Mafalda Ferreira, Isabel Ramos, and Pedro Melo Freitas
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Humans ,Neuroimaging ,General Medicine ,Neurocysticercosis - Published
- 2024
37. Eficiência técnica em propriedades leiteiras familiares no Estado de Minas Gerais em 2021
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Leandro Carvalho Bassotto, Gideon Carvalho de Benedicto, André Luis Ribeiro Lima, Marcos Aurélio Lopes, and Fernanda Albuquerque Merlo
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dairy farming ,Economics and Econometrics ,Data Envelopment Analysis (DEA) ,benchmark ,production scale ,escala de produção ,pecuária leiteira ,mão de obra familiar ,Análise por Envoltória de Dados (DEA) ,General Social Sciences ,family labor ,Forestry ,Agronomy and Crop Science - Abstract
Resumo: A pecuária leiteira familiar é relevante para a agropecuária nacional que, embora contribua com a geração de riqueza e renda, enfrenta baixas eficiência, produtividade e custos de produção elevados. Objetivou-se analisar a eficiência técnica de propriedades leiteiras familiares no Estado de Minas Gerais. Utilizou-se a Análise por Envoltória de Dados (DEA) com modelo BCC orientado a inputs. Quanto maior foi o nível de eficiência das DMU’s, menos recursos foram utilizados em excesso. Foi identificada, ainda, a inexistência de DMU’s que realizaram manutenção preventiva de máquinas, implementos e benfeitorias, justificando o aumento da utilização, principalmente, do insumo MIB (manutenção de máquinas, implementos e benfeitorias). Com esta pesquisa, sugeriu-se o Índice de Comprometimento de Insumos em Leite (ICIL), que evidencia o percentual da produção que está comprometida para comprar um determinado insumo. Quanto maior foi o nível de eficiência das DMU’s, menor foi o ICIL, que passou de 49,36% (eficientes) para 67,47% (com eficiência baixa). Este se mostrou um importante indicador de eficiência de propriedades leiteiras, responsável por evidenciar a quantidade de leite produzido que está comprometida com o pagamento dos insumos utilizados na atividade leiteira. Também se mostrou valioso instrumento a ser utilizado como benchmark em propriedades leiteiras. Abstract: Family dairy farming is relevant for national agriculture which, although it contributes to the generation of wealth and income, faces low efficiency, productivity and high production costs. The objective was to analyze the technical efficiency of family dairy farms in the State of Minas Gerais. Data Envelopment Analysis (DEA) with input-oriented BCC model was used. The higher the efficiency level of the DMUs, the fewer resources were used in excess. It was also identified the lack of DMUs that performed preventive maintenance of machines, implements and improvements, justifying the increase in the use, mainly, of the MIB input (maintenance of machines, implements and improvements). With this research, the Milk Input Commitment Index (ICIL) was suggested, which shows the percentage of production that is committed to purchase a given input. The higher the efficiency level of the DMUs, the lower the ICIL, which went from 49.36% (efficient) to 67.47% (low efficiency). This proved to be an important indicator of efficiency of dairy properties, responsible for showing the amount of milk produced that is committed to the payment of inputs used in the dairy activity. It also proved to be a valuable instrument to be used as a benchmark in dairy farms.
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- 2024
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38. Rates of Bootstrap Approximation for Eigenvalues in High-Dimensional PCA
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Junwen Yao and Miles Lopes
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Statistics and Probability ,Statistics, Probability and Uncertainty - Published
- 2024
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39. Iceberg lettuce cultivated in different systems of planting and sources of fertilizer
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R. Santos-Naressi, L. Santos-Pimentel-Oliveira, E. H. Santos, J. P. Francisco, and A. D. Lopes
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Plant Leaves ,Minerals ,Lactuca sativa ,fertilization ,fungi ,food and beverages ,Lettuce ,Plants ,General Agricultural and Biological Sciences ,Fertilizers ,vegetal cover - Abstract
Organic fertilization is a cheaper and highly effective option for profitability and consequent improvement of the soil's physical, chemical, and biological structure. Thus, the objective of this work was to evaluate different types of fertilization: organic (poultry shed litter), mineral, and leaf path on yield parameters of lettuce grown in various types of planting. The treatments consisted of using two planting systems (P1 - Line and P2 - quincunxes) and mineral and organic fertilizers (A1 - mineral fertilization; A2 - mineral fertilization + leaf fertilization; A3 - organic fertilization with poultry shed litter and A4 - fertilization organic + mineral). The experimental units consisted of 36 and 52 plants, respectively, for treatments P1 and P2, and all central plants of the experimental unit were evaluated. Heart height, fresh mass, and leaf number were observed. The mineral and mineral + leaf treatments did not differentiate, either in line or in quincunxes. The treatment that stood out about the analyzed variables was the organic fertilization and quincunxes planting system, reflecting a more significant number of lettuce plants and better use of the area.
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- 2024
40. Validação de instrumento para o risco clínico a criança hospitalizada
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Thalys Maynnard da Costa Ferreira, Ronny Anderson de Oliveira Cruz, Wellyson Souza do Nascimento, Josefa Danielma Lopes Ferreira, Marta Miriam Lopes Miriam Lopes Costa, and Kenya de Lima Silva
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General Medicine - Abstract
Objetivo: Averiguar a validade clínica de um instrumento para coleta de dados quanto à capacidade de mensurar as necessidades humanas básicas através do risco clínico de crianças entre 0 e 5 anos hospitalizadas. Métodos: Estudo metodológico, com abordagem quantitativa, realizado com 150 crianças em uma clínica pediátrica de um hospital escola. Resultados: Confirmou-se a existência dos grupos de baixo, médio e alto risco clínico. Quanto à diferenciação das crianças inseridas nos respectivos grupos, apresentou-se um Tukey test com escore total médio de 114,13 para alto risco. Como produto da aplicação do modelo descritivo de classificação binária Weight of Evidence, verificou-se alteração prioritária das necessidades de eliminação e nutrição. Após análise de agrupamento hierárquico, consolidou-se a informação de que houve grande similaridade entre as necessidades nutrição e hidratação, segurança e crescimento. Conclusão: Clinicamente, o instrumento mostrou-se válido quanto à capacidade de mensurar as alterações a partir do risco clínico.
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- 2023
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41. Ética e recursos humanos: o novo conceito de empresa
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Gabriel César Dias Lopes and Pollyanna Carvalho Pereira Lopes
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Este artigo discute o conceito de ética e aborda como ela é conceitualizada no modelo de empresa atual. Parte do pressuposto que dentro da questão das mudanças no paradigma conceitual de empresa, dois aspectos hoje se manifestam como de fundamental importância para o desenvolvimento da empresa, seja ela governamental, estatal ou privada. São a questão dos recursos humanos e a questão da ética. Para tanto se observa que os novos modelos e configurações da economia não substituirão os antigos por inteiro, mas conviverão com eles, transformando-os por meio de uma profunda interação das empresas, por meio da disseminação do conhecimento.
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- 2023
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42. Relationship between Ischemic Stroke and Atrial Fibrillation, Systematic Review
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Youssef Elias Ammar, Cristianne Confessor Castilho Lopes, Eduardo Barbosa Lopes, Lucas Castilho Lopes, Maria Eduarda Castilho Lopes, Carolina Alves Quintanilha, Eduardo Santanna Nubile, Isabella Cunha Barbosa, Guilherme Carrijo Olanda, Samara Maia Silva, Wendy Rodrigues Porto, Marilda Morais Da Costa, Tulio Gamio Dias, Kyra Esteves Ururahy Rodrigues, Lucas Sena Dos Santos Borges, Joacir Ferreira Junior, Heliude De Quadros E Silva, Fabio Herget Pitanga, Marivane Lemos, Daniela dos Santos, and Marcus Vinicius Vasconcelos Goncalves
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Ocean Engineering - Abstract
Introduction: Atrial Fibrillation (AF) is not only one of the main causes of stroke, but it is also the most common sustained cardiac arrhythmia. As a result of population aging, an increase in the prevalence of AF and other associated chronic cardiovascular diseases, such as Systemic Arterial Hypertension (SAH) and Diabetes Mellitus (DM), is expected, contributing to a higher incidence of stroke. The magnitude of this fact reflects the reason why stroke is considered the second cause of death in the world, and the first cause of death in Brazil, in addition to being the second cause of cognitive losses. The main causes that favor the occurrence of ischemic stroke determine the situation of risk groups. Such factors can be classified as modifiable, non-modifiable and potential risk group. Objective: The aim of this study was to systematically review the public health literature on the relationship between ischemic stroke and atrial Fibrillation. Methods: Systematized literature review performed by searching the Web of Science database (Clarivates), Science Direct (Scopus), Wiley Online Library (John Wiley and Sons), Taylor and Francis (Taylor & Francis Group) and PubMed (NIH), using the descriptors Relationship between Ischemic Stroke and Atrial Fibrillation and other cardiovascular diseases in primary care, both in English and Portuguese. A total of 3860 articles were found, of which 64 were selected for the review by six evaluators independently. The articles surveyed are from the period 2015 to 2022. Results: In addition to the epidemiological magnitude, AF is important for its clinical consequences, including thromboembolic occurrences, with an increase, on average, of 4 times the probability of a stroke, in addition to being correlated with the high risk of all-cause mortality and other circumstantial determinants, such as heart failure. Conclusion: The analyzed studies demonstrated that there may be an adjusted incidence of ischemic stroke associated with AF and other cardiovascular diseases by stroke age, being age dependent in men. Social factors may contribute to the late discovery of the association between stroke, AF and other cardiovascular diseases.
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- 2023
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43. Exosome membrane-coated nanosystems: Exploring biomedical applications in cancer diagnosis and therapy
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Shao, Minmin, Lopes, Daniela, Lopes, Joana, Yousefiasl, Satar, Macário-Soares, Ana, Peixoto, Diana, Ferreira-Faria, Inês, Veiga, Francisco, Conde, João, Huang, Yi, Chen, Xianfeng, Paiva-Santos, Ana Cláudia, and Makvandi, Pooyan
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General Materials Science - Published
- 2023
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44. Direct visualization of transcription-replication conflicts reveals post-replicative DNA:RNA hybrids
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Stoy, Henriette, Zwicky, Katharina, Kuster, Danina, Lang, Kevin S, Krietsch, Jana, Crossley, Magdalena P, Schmid, Jonas A, Cimprich, Karlene A, Merrikh, Houra, Lopes, Massimo, University of Zurich, and Lopes, Massimo
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1315 Structural Biology ,Structural Biology ,10061 Institute of Molecular Cancer Research ,1312 Molecular Biology ,570 Life sciences ,biology ,610 Medicine & health ,Molecular Biology - Abstract
Transcription-replication collisions (TRCs) are crucial determinants of genome instability. R-loops were linked to head-on TRCs and proposed to obstruct replication fork progression. The underlying mechanisms, however, remained elusive due to the lack of direct visualization and of non-ambiguous research tools. Here, we ascertained the stability of estrogen-induced R-loops on the human genome, visualized them directly by electron microscopy (EM), and measured R-loop frequency and size at the single-molecule level. Combining EM and immuno-labeling on locus-specific head-on TRCs in bacteria, we observed the frequent accumulation of DNA:RNA hybrids behind replication forks. These post-replicative structures are linked to fork slowing and reversal across conflict regions and are distinct from physiological DNA:RNA hybrids at Okazaki fragments. Comet assays on nascent DNA revealed a marked delay in nascent DNA maturation in multiple conditions previously linked to R-loop accumulation. Altogether, our findings suggest that TRC-associated replication interference entails transactions that follow initial R-loop bypass by the replication fork.
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- 2023
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45. Ischemic Stroke of Cardioembolic Origin Systematic Review
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Youssef Elias Ammar, Cristianne Confessor Castilho Lopes, Eduardo Barbosa Lopes, Lucas Castilho Lopes, Maria Eduarda Castilho Lopes, Carolina Alves Quintanilha, Eduardo Santanna Nubile, Isabella Cunha Barbosa, Guilherme Carrijo Olanda, Samara Maia Silva, Wendy Rodrigues Porto, Marilda Morais da Costa, Tulio Gamio Dias, Kyra Esteves Ururahy Rodrigues, Lucas Sena dos Santos Borges, Joacir Ferreira Junior, Heliude de Quadros e Silva, Fabio Herget Pitanga, Marivane Lemos, Daniela dos Santos, and Marcus Vinicius Vasconcelos Goncalves
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Ocean Engineering - Abstract
Ischemic stroke corresponds to 80% of cases in Brazil, which demonstrates the epidemiological importance in Brazil. The magnitude of this fact reflects the reason why stroke is considered the second cause of death in the world, and the first cause of death in Brazil, in addition to being the second cause of cognitive losses. The main causes that favor the occurrence of ischemic stroke determine the situation of risk groups. Such factors can be classified as modifiable, non-modifiable and potential risk group.
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- 2023
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46. Congenital syphilis evaluated for syphilitic hepatitis - case series
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Izailza Matos Dantas Lopes, Gabriel Dantas Lopes, Jefferson Felipe Calazans Batista, José Rodrigo Santos Silva, Francisco Prado Reis, and Sonia Oliveira Lima
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General Medicine - Abstract
Objective: To report case series evaluated for congenital syphilitic hepatitis. Method: Study conducted at Maternity Santa Isabel from December 2021 to May 2022. We evaluated newborns with congenital syphilis using data taken from the pregnant woman’s card, the child’s card, the anamnesis and exams performed in the follow-up consultations of these families. Complete medical records of infants who presented the criteria for the diagnosis of congenital syphilis of the Ministry of Health and the Center for Disease Transmission Control were included. Results: The review was 15 of which were selected that fit all the inclusion criteria. The babies were born with good vitality, term, one had low birth weight, six hepatomegaly, all treated with penicillin, nine had altered liver biochemical tests. At ultrasonography, Doppler was normal for all, one case of hepatosplenomegaly and one with splenomegaly. Two mothers who were diagnosed at the time of delivery had fewer than six consultations, their babies had neurosyphilis and presented developmental alertness. The child who had microcephaly and low birth weight also presented altered neurodevelopment. Of the pregnant women, three were over 30 years old, one was white, five had studied less than 8 years, thirteen were not working, family income of 1 minimum wage or less in twelve families. Eight were inadequately treated. Of the parents, eleven had studied less than 8 years and eleven were inadequately treated. Conclusion: The children with syphilis were born vigorous and had adequate treatment. Nine had altered hepatic biochemical exams, two had ultrasonographic alterations, however, without alterations in the Doppler. The children of untreated mothers had neurosyphilis and neurodevelopmental changes.
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- 2023
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47. Surf-zone fish assemblage structure and its diel variability in an ocean beach of Espírito Santo (Central Brazilian coast)
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Riguel Feltrin Contente, Camila Marion, João Victor Silva, Marcelo Soeth, Mario Vinicius Lopes Condini, Lorena Lopes Almeida, Henry Louis Spach, and Mauricio Hostim-Silva
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Aquatic Science ,Oceanography - Abstract
We characterized the surf-zone fish assemblage structure of an ocean beach on the central coast of Brazil (Guriri Beach, Espírito Santo) and assessed its diel variability. Like the entire Espírito Santo coast, Guriri Beach was also affected by ore tailings from the Fundão dam, which collapsed on November 5, 2015. Monthly samplings were carried out before the dam collapse along a year cycle (May 2013-April 2014), during the day and night in the neap tide, using a beach seine. A total of 2217 specimens were caught (1017 during the day and 1200 at night), distributed in 36 fish species and 20 families. Juveniles of the kingcroaker Menticirrhus spp., great pompano Trachinotus goodei, Florida pompano Trachinotus carolinus, littlescale threadfin Polydactylus oligodon, and Atlantic sabretooth anchovy Lycengraulis grossidens dominated the fish fauna, accounting for 84% of the total capture. The fish assemblage structure changed irregularly between day and night throughout the year. P. oligodon and Menticirrhus spp. were more abundant at night, whereas T. carolinus and L. grossidens were more abundant during the day. In most cases, no significant change was detected in fish abundance and richness between the day and night; when significant differences were detected, abundance and richness were higher at night. Our findings could support a monitoring program of the local surf-zone fish fauna and serve as before-impact data, allowing more accurate quantification of the ore tailings' impacts on the local fish biodiversity.
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- 2023
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48. Os principais tipos e manifestações da Cirrose Hepática: uma atualização clínica
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Maria Sílvia Prestes Pedrosa, Levi Lopes Bragança, Luísa Costa Menezes, Rogério Marques Guimarães, Fernando Henrique Sampaio De Souza, Maria Eduarda Renaud De Oliveira, Nayara Vellano Pinheiro Sampaio, Karolina Cristina Gonçalves, Leandro Jaime Barreto Costa, José Ricardo Baracho Dos Santos Júnior, Gabriel Ferrari Alves, Vitoria Schütt Zizemer, Thales Fernando Canabarro Araujo, Beatriz Rêgo Lobato, Renato Palmeira Lopes Pereira, Taynara Pinheiro Carvalho Catarina, Francisco Airton Veras De Araújo Júnior, Jéssica de Vasconcelos Oliveira Viégas, Kelly Ribeiro Moura Barboza, Gean Carlos Costa, Augusto Cesar Fracaro, Daniel Kendi Hirokawa De Lima, Humberto Lora Formigheri, Vitória Ribeiro Farinha, Caio Henrique Freitas Fernandes, Karina Alves Magalhães, Stephanie Figueiredo de Barros Moreira, Matheus Mendes Maranhão, Ana Luiza Ribeiro Barroso Maia, José Joceilson Cruz De Assis, Caio César Ferreira, Maria Eduarda de Quadros Batistello, Deyse Caldas Santos, Carolina Neuenfeld Pegoraro, Karina Marques Milhomem De Sousa, Leonardo Wilner Barros Silva, Ariane Gomes Duvale, Chabely Sanchez Morera, Marília Mendes De Oliveira, Erika Leite Moitinho Magalhães De Almeida, Letizia Di Mango Feitoza Dos Santos, Taissa Ellen Ferrari Santos, Raíssa Corrêa Torres, Dayane Porto Silva, and Ingra Dalcin Pereira
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General Medicine - Abstract
Introdução: A cirrose hepática é um processo patológica crônico, considerado a hepatopatia mais comum, definido como a conversão difusa morfoestrutural por nódulos de arquitetura anômalo envoltos por fibrose. Objetivou-se descrever os tipos mais relevantes de cirrose e suas devidas manifestações. Metodologia: Trata-se de uma revisão bibliográfica, fundamentada nas plataformas do SciELO, PubMed, Scopus, utilizando os termos “hepatical cirrhosis”, “liver disease” e “hepatocellular insufficiency” a qual através da revisão narrativa, abordou amplamente a respeito da contextualização da cirrose e as principais etiologias. Resultados e Discussão: Foi analisado que tal condição afeta qualquer faixa etária, sexo, etnia e independe da classe socioeconômica, mas as diversas etiologias impõem um perfil epidemiológico específico conforme a aparição. As principais origens abordam o tipo alcoólico, hepatite, aplicação crônica de alguns fármacos e esteatose gordurosa ou não. Ademais, estima-se que estas afetam a anatomofuncionalidade do órgão responsável por grande parte da homeostase, culminando em diversas manifestações clínicas. Conclusão: A cirrose é uma consequência grave de fatores de base em estágio avançado, a qual devido ao seu curso geralmente silencioso culmina no desenvolvimento e progressão clínica. Neste contexto, a atenção aos fatores predisponentes como alimentação rica em lipídios, estilismo, negligência a exames de rotina, sedentarismo e obesidade contribuem constituem medidas eficazes de prevenção primária.
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- 2023
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49. Ecologia Política, Agroecologia e Comunidades Tradicionais
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Keila Cássia Santos Araújo Lopes, null Gabriel Romagnose Fortunato de Freitas Monteiro, and null Paulo Rogério Lopes
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Ecologia Política, Agroecologia e Comunidades Tradicionais (DOSSIÊ) Ecologia Política, Agroecologia e Comunidades Tradicionais (DOSSIÊ) Um novo alvorecer desponta após tempos nebulosos marcados pelo desgoverno, num período marcado por ações antidemocráticas, anti-educadoras, anticientíficas e anticulturais (2019-2022), que culminou no descaso, descompromisso e violência com os Povos e as Comunidades Tradicionais, flexibilização na legislação e fiscalização ambiental, desmonte de políticas públicas; incoerência, negacionismos, incompetência e irresponsabilidade nas mais diversas esferas e áreas, a exemplo da desastrosa atuação durante a pandemia no Brasil (vírus SARS-CoV- 2/COVID-19), abandono do povo Yanomami, avanço da liberação de novos agrotóxicos, apoio ao garimpo e desmatamento ilegal das florestas brasileiras e insegurança alimentar em todas regiões (volta do Brasil ao mapa da fome). Como consequência dessas medidas, assistimos a um massacre dos povos originários ocasionada pela depredação dos bens naturais (solo, água, matas, fauna) e socioagrobioiversidade que traz consequências no tocante à soberania e segurança alimentar, bem como à saúde socioambiental. Crianças, homens, mulheres, jovens e idosos têm sido vítimas da mineração em terras já demarcadas, sendo acometidas por enfermidades, contaminação por mercúrio, fome, desnutrição, miséria e morte. Como se não bastasse, a agricultura familiar camponesa e as políticas públicas, ministérios, institutos e secretarias vinculadas a essa categoria foram sucateadas, fragilizados e/ou paralisadas, a exemplo do Programa Nacional de Educação para a Reforma Agrária (PRONERA), Programa Nacional de Alimentação Escolar (PNAE), Programa de Aquisição de Alimentos (PAA), Política Nacional de Assistência Técnica e Extensão Rural (PNATER), Política Nacional de Agroecologia e Produção Orgânica (PNAPO), Ministério do Desenvolvimento Agrário (MDA), Instituto Nacional de Colonização e Reforma Agrária (INCRA), espaços consultivos, etc. A depredação das florestas e perda da sociobiodiversidade tem como principal agente promotor a política destrutiva empreendida nos últimos anos, pautada no avanço do agronegócio, mineração, pesca predatória, garimpo, dentre outros. Esse viés produtivista e economicista, desconsidera os valores biológicos (serviços ecossistêmicos), monetários (uso sustentável) e simbólicos (materiais e imateriais) das florestas “em pé”. Nesta racionalidade, de uma modernidade-colonial, a Natureza é vista meramente como recurso econômico a ser explorado pelo capital. A perda das áreas florestadas e biodiversidade ocasionam desequilíbrios ecológicos, climáticos, sociais, energéticos e produtivos. O desmatamento, além de levar à extinção de espécies, contribui com as alterações climáticas (veranicos e secas mais prolongadas, chuvas de granizo, aumento da temperatura, etc.) percebidas cada vez mais em todo planeta Terra. Os gases de efeito estufa contribuem com o aquecimento da Terra, desencadeando desequilíbrios e impactos socioambientais com consequências avassaladoras, tais como: calor e frio intensos, desertificação, chuvas com índices pluviométricos elevadíssimos e incomuns, desabamento de encostas e inundações, afetando principalmente as populações de baixa renda que habitam as áreas de risco, em situações precárias, fato desencadeado pela intensa desigualdade social que, por sua vez, culmina em injustiças ambientais. A Ecologia Política apresenta um compromisso voltado para a denúncia das injustiças ambientais, bem como, o campo de estudo dos conflitos socioambientais oriundos do uso, apropriação e acesso aos bens naturais. O modelo econômico vigente é altamente excludente, predatório e desencadeia tais conflitos. Nesse sentido, torna-se importante destacar o relevante papel de proteção e conservação dos bens naturais que as comunidades tradicionais, representadas pelos Povos originários, Quilombolas, Quebradeiras de coco, Marisqueiras, Seringueiros, Caiçaras, Ribeirinhos, dentre tantas outras experiências situacionais tipificadas , exercem e são explicitadas em sua relação direta e respeitosa com a natureza, seja por meio de suas práticas seculares de manejo, espiritualidades e simbologias, bem como pela reprodução sócio cultural e biológica existente. Outrossim, nesta perspectiva, as racionalidades cosmogônicas operam no e pelo espaço, no campo das horizontalidades contra-hegemônicas, cuja relação Sociedade(s)-Natureza se afirma nos territórios e territorialidades insurgentes e confluentes. A Agroecologia enquanto ciência, prática e movimento dialoga com a Ecologia Política, pois ambas valorizam os saberes populares, as comunidades tradicionais e suas organizações (movimentos sociais, redes, articulações, etc.), valores e práticas. Como ciência, a Agroecologia possui princípios, práticas e métodos para avaliação, construção e transição para sistemas, territórios e sociedades sustentáveis. Enquanto movimento social, a Agroecologia se concretiza com a valorização e articulação política dos povos dos campos, das águas, das florestas e cidades, engajados na construção de territórios sustentáveis, soberanos, livres de agrotóxicos e transgênicos, do racismo ambiental, do patriarcado e outros tipos de preconceitos. A agenda da reforma agrária popular e, portanto, da justiça socioambiental, é construída diariamente, a partir da base, das redes políticas de resistência e das políticas de escalas. Esse dossiê intitulado “Ecologia Política, Agroecologia e Comunidades Tradicionais” apresentará ao leitor contribuições científicas, práticas, políticas, técnicas e experiências educadoras inerentes ao campo teórico da Agroecologia, Geografia Agrária, Geografia Socioambiental, Geografia Política e Educação do Campo. Os textos apresentados, certamente, trarão aproximações teóricas, inquietações, conhecimentos, reflexões e aplicações que possam contribuir com empoderamento, governança territorial e processos de transição agroecológica para territórios, sistemas e sociedades sustentáveis, justas e igualitárias. O texto “Conservação Ambiental e Soberania Territorial na Baía de Todos os Santos”, da autoria de Paula Regina de Oliveira Cordeiro, reflete a existência de inúmeras comunidades tradicionais que compõem a diversidade da Baía de Todos os Santos (BTS), com destaque para as comunidades pesqueiras e quilombolas. O texto aborda como tais comunidades atuam como guardiãs da sociobiodiversidade, a partir das práticas espaciais ancestrais, ao construírem seus territórios e territorialidades. A cosmopercepção africana da natureza é enfatizada ao discutir a gestão do território por essas comunidades. Além disso, são discutidas as relações conflituosas atravessadas nesses territórios com os empreendimentos industriais ou do turismo, bem como os processos de resistência. O ensaio “Cosmologia e Kilombus: território ancestral e a Retomada originária”, da autoria de Makota Kidoiale e Jair da Costa Junior, produz uma crítica aos modos de vida das sociedades ocidentais ou ocidentalizadas contemporâneas, às quais exploram, incessantemente, os recursos da natureza e produzem uma relação hierárquica com esta. Em contrapartida, são apresentadas as epistemologias e cosmologias do povo negro, sobretudo dos Povos de Santo, transmitidos por meio das tradições orais, herança ontológica e cosmológica das sociedades africanas. A perspectiva da filosofia Ubuntu é discutida na raiz dos povos africanos e afro-brasileiros. No que tange à Retomada como processo contra-colonial, é enfatizado seu sentido cosmológico, uma cosmopercepção radical, ou seja, a construção de uma outra relação sociedade(s) e natureza que deverá alterar a organização das relações sociais, ambientais, institucionais, políticas etc. “O debate sobre a Agroecologia no MST: as práticas de produção no campo e a relação socioambiental”, da autoria de Custódio Jovêncio Barbosa Filho e Elizete Oliveira de Andrade apresenta os resultados da pesquisa “Educação do Campo e Agroecologia: interfaces entre o saber científico e o saber popular”. O texto aborda a metodologia do círculo de cultura de Paulo Freire para compreender e analisar a atuação dos trabalhadores e trabalhadoras do Assentamento Olga Benário, situado em Visconde do Rio Branco, em seus processos organizativos para a produção voltada aos princípios da Agroecologia. A leitura do texto “Conflitos socioambientais no território do Extremo Sul da Bahia e a Escola Popular de Agroecologia e Agrofloresta Egídio Brunetto: a luta popular e as estratégias pedagógicas libertadoras na construção da Agroecologia”, da autoria de Felipe Otávio Campelo e Silva, Fábio Frattini Marchetti, Meriely Oliveira de Jesus, Dionara Soares Ribeiro e Valdete Oliveira Santos enfatiza a importante atuação do Movimento dos Trabalhadores Rurais Sem Terra (MST) na construção da Reforma Agrária Popular, a partir da análise histórica dos conflitos socioambientais das últimas décadas no território do Extremo Sul da Bahia. Enfatiza, portanto, o potencial de ferramentas pedagógicas e espaços educadores, cujos resultados apontam para novas possibilidades na construção popular da Agroecologia, bem como, na elaboração de parâmetros para a formulação de políticas públicas. O artigo “Trajetórias em Projetos de Extensão Universitária: tecendo saberes geográficos e agroecológicos”, da autoria de Keila Cássia Santos Araújo Lopes, Izabela Obolari Protasio, Samara de Matos Silva, Mariana Soares Domingues, Gabriel Romagnose Fortunato de Freitas Monteiro e Paulo Rogério Lopes traz o percurso de construção do projeto de extensão “Tecendo saberes e cultivando alimentos: a Geografia na construção de processos educadores e territórios sustentáveis”, bem como, das ações, parcerias e criação do Núcleo de Estudos em Agroecologia (NEA) Jequitibá Rosa na Universidade do Estado de Minas Gerais - unidade Carangola. Por fim, temos um texto relacionado às experiências práticas no campo da Agroecologia. O artigo “Uso da farinha de caranguejo-uçá no cultivo agroecológico de alface americana: uma experiência conjunta de uma Reserva Extrativista (Resex) com uma Escola Popular de Agroecologia”, da autoria de Iara Maria Lopes Rangel, Victoria Santos Souza e Rafael Passos Rangel apresenta uma alternativa de uso sustentável ao resíduo do caranguejo-uçá utilizada pela comunidade de povos extrativistas no Extremo Sul da Bahia, como fonte nutritiva à olerícola. Os textos do dossiê “Ecologia Política, Agroecologia e Comunidades Tradicionais” trazem diferentes abordagens temáticas no campo dos conflitos socioambientais, movimentos sociais do campo, da educação em Agroecologia, de práticas de manejo sustentáveis em comunidades, bem como, de suas cosmovisões. Frente à amplitude de assuntos pertinentes, contemporâneos e contextualizadores, esperamos que todas, todes e todos desfrutem de boa leitura! Organizadores Keila Cássia Santos Araújo Lopes - Geografia - UEMG/Carangola Gabriel Romagnose Fortunato de Freitas Monteiro - Geografia - UEMG/Carangola Paulo Rogério Lopes - Agroecologia - UFPR Litoral/Matinhos
- Published
- 2023
- Full Text
- View/download PDF
50. Geografia e Agroecologia: trajetória, vivências e experiências construídas
- Author
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Keila Cássia Santos Araújo Lopes, Izabela Obolari Protasio, Samara Matos Silva, Mariana Soares Domingues, Gabriel Romagnose Fortunato de Freitas Monteiro, and Paulo Rogério Lopes
- Abstract
O presente artigo tem como objetivo apresentar a trajetória, vivências e experiências oriundas do projeto de extensão “Tecendo saberes e cultivando alimentos – a Geografia na construção de processos educadores e territórios sustentáveis”. O referido projeto possui como objetivo suleador, a promoção de diálogos e práticas que promovam vivências, experiências com a Geografia Socioambiental e sua interface com Agroecologia, no intuito de possibilitar, sobretudo, reflexões sobre o modelo de produção agrícola capitalista e suas consequências para os seres humanos e o ambiente, bem como, elucidar o necessário e urgente processo transformador visando sociedades sustentáveis. O projeto vem sendo desenvolvido com atividades de formação dos estudantes bolsistas, voluntários, construção de materiais que dialogam com as temáticas centrais e práticas em escolas públicas. Portanto, o projeto tem contribuído, para além da formação pedagógica, conceitual e prática dos estudantes, mas também na relação e aproximação com o espaço escolar, essencial para a docência.
- Published
- 2023
- Full Text
- View/download PDF
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