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The coronavirus (COVID-19) has challenged healthiness careers and techniques and has induced several rates of reaction and forms of reaction worldwide. The responsibility of dental specialists in inhibiting the transmission of COVID-19 is seriously significant. Dental professionals suffered a proper duty to decrease routine care for fear of increasing COVID-19 among their patients and elsewhere but were understandably concerned about the economic concerns. This paper explores comments raised by orthodontists worldwide about offering safe orthodontic service during the ongoing COVID-19 pandemic, as orthodontic treatment procedures increase the possibility of transmission. As proximity between the orthodontist, dental assistant, and patient is required for treatment, it jeopardizes the health of all the parties involved. In this paper, we will highlight five issues: general principles, communication, dental clinic admission, infection control measures, and applied orthodontic treatment emergency. Upon reviewing these issues, we will then attempt to formulate appropriate orthodontic treatment guidelines applicable in this specific era.