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6. Questioning the Potential for Achieving Active Ageing in Bucharest

Author

Camelia Surugiu, Ana - Irina Lequeux - Dinca, Ana-Maria Talos, Mihaela Preda, and Alina Mareci

Subjects
Geography, Planning and Development
Abstract

The continuous growth of elderly population cohorts represents a global phenomenon influencing the design of any country’s economic and social policies. In the present context, an urban development planning challenge is encouraging an active and healthy lifestyle, transforming seniors into an economically and socially active group that further ensures their successful active ageing and respects place attachment values. This study aims to depict an overall image of the possibility to achieve active ageing for Bucharest’s elderly and their perception of this matter. In order to do so, the research appealed to the survey method for a total sample of 402 residents aged 65+ and living in all districts of Bucharest. The research objectives follow the main pillars of the active ageing concept that is assessing: their financial security and reasons motivating them to work after retiring, their capacity and needs for independent living, their access to health services and the enabling environment, which can act both as a facilitator and a barrier. The main results reveal that an active lifestyle depends on socio-economic and psychological characteristics and that the elderly’s contribution to economic life is often a continuation of their previous activities, not necessarily a result of successful policies for achieving active ageing. All these, next to low revenues, low access to health care, and limited usage capacity for ICT tools, define obvious difficulties for designing future urban friendly-ageing policies in Bucharest. This research represents a valuable contribution from the pre-COVID period, which may be complemented by further studies that contrast current perspectives on the topic.

Published
2022

7. LIFE AT MEUDON OBSERVATORY, 1876-1963

Author

Lequeux, James and bibliotheque, la.

Subjects
Bertaud, Muller, History, Trouvelot, Physics and Astronomy (miscellaneous), Deslandres, Rabourdin, Grenat, Dunoyer de Segonzac, [PHYS.PHYS.PHYS-HIST-PH] Physics [physics]/Physics [physics]/History of Physics [physics.hist-ph], Paris-Meudon Observatory, Astronomy and Astrophysics, Danjon, d'Azambuja, Antoniadi, Lyot, Baldet, Dauvillier, Mărăcineanu, Denisse, Esclangon, Perot, [PHYS.ASTR] Physics [physics]/Astrophysics [astro-ph], Mount Blanc Observatory, Janssen
Abstract

Meudon Observatory was created for Janssen in 1876 for physical astronomy, as a reaction to the conservative Paris Observatory. It merged in 1927 with this observatory, while keeping in practice some autonomy. It was very well equipped, with a great equatorial, a 1-m reflecting telescope and several novel solar instruments, but except for the latter they were not very much used due to lack of personnel and because of technical deficiencies. A modern equatorial table was installed in 1931 and became the main non-solar instrument. A physics laboratory had been installed from the beginning, producing data useful for astronomy; it was the responsibility of a 'Physicist of the Observatory'. In this paper, I describe the life at Meudon until the arrival of radio astronomers in 1956 and the nomination in 1963 of a radio astronomer as director, events that produced considerable changes in Meudon Observatory.

Published
2022

11. Swine Breeding in the Villages of Vâlcea County, Oltenia (Romania)—Tradition or Necessity?

Author

Szemkovics, Camelia Teodorescu, Marin Burcea, Ana-Irina Lequeux-Dincă, Florentina-Cristina Merciu, Adrian-Nicolae Jipa, and Laurenţiu-Ştefan

Subjects
animal breeding, economic crisis, local culture, rural economy, cluster analysis
Abstract

Food supply has been a constant source of concern for mankind. In the present context, with food security a priority of European and national policies, an analysis of pig farming in a representative NUTS2 administrative level of Romania that emphasizes the proportion of households raising at least one pig and the main factors influencing farmers to adopt or give up swine breeding could allow a much clearer understanding of this phenomenon that lies at the border between cultural tradition and socio-economic necessity. This study uses mixed methods that complement each another to help reveal this complex phenomenon in the analyzed territory. Cluster analysis shows the concentration of swine breeding and maps its spread in terms of both subsistence and larger farms, and qualitative interviews prove the motivation of farmers to continue in this occupation. As a primary result, the study visualizes the spatial distribution of pig farming in the rural environment of Vâlcea county, Romania, from a diachronic perspective in the post-communist period. It also reveals areas of differing concentrations of both very small-sized farms, which prioritize meeting their own food needs, and larger farms, which prioritize commercial production to supplement their revenue streams. Both categories, but particularly the latter, are of particular interest in a period in which the socio-economic environment after 1990—marked by economic restructuring, unemployment, population migration, the economic crisis of 2008–2010, the pandemic of 2020–2021, and the most recent energy crisis—periodically highlights the importance of rural areas in ensuring food security and sufficiency at both the local and regional levels.

Published
2023
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12. Optimisation of treatments for heart failure with reduced ejection fraction in routine practice: a position statement from a panel of experts

Author

Girerd, Nicolas, Leclercq, Christophe, Hanon, Olivier, Bayés-Genís, Antoni, Januzzi, James, Damy, Thibaut, Lequeux, Benoit, Meune, Christophe, Sabouret, Pierre, Roubille, François, Défaillance Cardiovasculaire Aiguë et Chronique (DCAC), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Centre d'investigation clinique plurithématique Pierre Drouin [Nancy] (CIC-P), Centre d'investigation clinique [Nancy] (CIC), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL)-Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lorraine (UL), Cardiovascular and Renal Clinical Trialists [Vandoeuvre-les-Nancy] (INI-CRCT), Institut Lorrain du Coeur et des Vaisseaux Louis Mathieu [Nancy], French-Clinical Research Infrastructure Network - F-CRIN [Paris] (Cardiovascular & Renal Clinical Trialists - CRCT ), Laboratoire Traitement du Signal et de l'Image (LTSI), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Pontchaillou [Rennes], Hôpitaux Universitaires Paris Centre, Université Paris Cité (UPCité), Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Germans Trias i Pujol University Hospital [Badalona, Barcelona, Spain] (GTPUH), Massachusetts General Hospital [Boston], Harvard Medical School [Boston] (HMS), Baim Institute for Clinical Research Boston MA, CHU Henri Mondor [Créteil], Service de cardiologie [CHU de Poitiers], Centre hospitalier universitaire de Poitiers (CHU Poitiers), Hôpital Avicenne [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Institut de cardiologie [CHU Pitié-Salpêtrière], CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046] (PhyMedExp), and Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM)

Subjects
Titration, Cardiovascular diseases, [SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular system, Practice guidelines treatment algorithm, Heart failure, Treatment optimization, [SDV.IB]Life Sciences [q-bio]/Bioengineering, General Medicine
Abstract

International audience; Major international practice guidelines recommend the use of a combination of 4 medication classes in the treatment of patients with heart failure with reduced ejection fraction (HFrEF) but do not specify how these treatments should be introduced and up-titrated. Consequently, many patients with HFrEF do not receive an optimized treatment regimen. This review proposes a pragmatic algorithm for treatment optimization designed to be easily applied in routine practice. The first goal is to ensure that all 4 recommended medication classes are initiated as early as possible to establish effective therapy, even at a low dose. This is considered preferable to starting fewer medications at a maximum dose. The second goal is to ensure that the intervals between the introduction of different medications and between different titration steps are as short as possible to ensure patient safety. Specific proposals are made for older patients (> 75 years) who are frail, and for those with cardiac rhythm disorders. Application of this algorithm should allow an optimal treatment protocol to be achieved within 2-months in most patients, which should the treatment goal in HFrEF.

Published
2023

13. Quantitative Visualization of Thermally Enhanced Perpendicular Shape Anisotropy STT-MRAM Nanopillars

Author

Trevor P. Almeida, Steven Lequeux, Alvaro Palomino, Ricardo C. Sousa, Olivier Fruchart, Ioan-Lucian Prejbeanu, Bernard Dieny, Aurélien Masseboeuf, David Cooper, Commissariat à l'énergie atomique et aux énergies alternatives - Laboratoire d'Electronique et de Technologie de l'Information (CEA-LETI), Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), SPINtronique et TEchnologie des Composants (SPINTEC), Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA), and European Project: 669204,H2020,ERC-2014-ADG,MAGICAL(2015)

Subjects
thermomagnetic stability, nanomagnetism, Mechanical Engineering, Perpendicular shape anisotropy STT MRAM, off-axis electron holography, [PHYS.COND.CM-MS]Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci], General Materials Science, Bioengineering, General Chemistry, Condensed Matter Physics
Abstract

International audience; Perpendicular shape anisotropy (PSA) offers a practical solution to downscale spin-transfer torque magnetoresistive random-access memory (STT-MRAM) beyond the sub-20 nm technology node while retaining thermal stability. However, our understanding of the thermomagnetic behavior of PSA-STT-MRAM is often indirect, relying on magnetoresistance measurements and micromagnetic modeling. Here, the magnetism of a NiFe PSA-STT-MRAM nanopillar is investigated using off-axis electron holography, providing spatially resolved magnetic information as a function of temperature. Magnetic induction maps reveal the micromagnetic configuration of the NiFe storage layer (∼60 nm high, ≤20 nm diameter), confirming the PSA induced by its 3:1 aspect ratio. In situ heating demonstrates that the PSA of the storage layer is maintained up to at least 250 °C, and direct quantitative measurements reveal a moderate decrease of magnetic induction. Hence, this study shows explicitly that PSA provides significant stability in STT-MRAM applications that require reliable performance over a range of operating temperatures.

Published
2022

15. Virtual approach of the aesthetical fit between hair colours and skin tones in women of different ethnical origin backgrounds

Author

Anthony Galliano, Myriam Guerin, Valerie Lambert, Ioanna Favrot, David Seneca, Fabien Lequeux, Frédéric Flament, Anna Sleurs, Berkly Foster, Edmund Phung, Kyung Moon Lee, and Jeff Houghton

Subjects
Asian People, Artificial Intelligence, Humans, Female, Skin Pigmentation, Dermatology, Hair Color, Genetic Background
Abstract

To determine the aesthetical accordance between a given skin tone and the 11 possible colours of head hairs, covered by a marketed hair colouration product.The photographs of professional top models, representing several ancestries (non-Hispanic European and Euro-American, East Asian, Hispanic Euro-American, and African-American ancestries), were used to virtually modify skin tones (from light, medium to dark) and hair colour by an artificial intelligence (AI)-based algorithm. Hence, 117 modified photographs were then assessed by five local panels of about 60 women each (one in China, one in France and three in US). The same questionnaire was given to the panels, written in their own language, asking which and how both skin tones and hair colours fit preferentially (or not appreciated), asking in addition the reasons of their choices, using fixed wordings.Answers from the five panels differed according to origin or cultural aspects, although some agreements were found among both non-Hispanic European and Euro-American groups. The Hispanic American panel in US globally much appreciated darker hair tones (HTs). Two panels (East Asian in China and African American in US) and part of non-Hispanic European panel in France declared appreciating all HTs, almost irrespective with the skin tone (light, medium and dark). This surprising result is very likely caused by gradings (in %) that differ by too low values, making the establishment of a decisive or significant assessment. By nature highly subjective (culturally and/or fashion driven), the assessments should be more viewed as trends, an unavoidable limit of the present virtual approach. The latter offers nevertheless a full respect of ethical rules as such objective could hardly be conducted in vivo: applying 10 or 11 hair colourations on the same individual is an unthinkable option.The virtual approach developed in the present study that mixes two major facial coloured phenotypes seems at the crossroad of both genetic backgrounds and the secular desire of a modified appearance. Nonetheless, this methodology could afford, at the individual level in total confidentiality, a great help to subjects exposed to some facial skin disorders or afflictions.

Published
2022

16. A HISTORY OF ASTRONOMICAL OPTICS IN FRANCE

Author

Lequeux, James, Georgelin, Yvon, POTHIER, Nathalie, Laboratoire d'Etude du Rayonnement et de la Matière en Astrophysique et Atmosphères = Laboratory for Studies of Radiation and Matter in Astrophysics and Atmospheres (LERMA), École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-CY Cergy Paris Université (CY), Laboratoire d'Astrophysique de Marseille (LAM), and Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)

Subjects
siderostat, History, Physics and Astronomy (miscellaneous), interferometer, polarimeter, Cassegrain telescope, coronagraph, Danjon astrolabe, instruments for astrometry, Astronomy and Astrophysics, 2022JAHHvol25/2022JAHH...25...03L.pdf, quadrant, adaptive optics, speckle interferometry, [SDU] Sciences of the Universe [physics], [SDU]Sciences of the Universe [physics], coelostat, photometer, Richey-Crétien telescope, spectrometer, coudé equatorial, Lyot's polarizing filter
Abstract

International audience; In this paper, we explore the advances made in France in astronomical optics. They were quite important in the seventeenth century thanks to Mersenne, Auzout and Picard. Progress in the eighteenth century was less remarkable and many instruments had to be imported from England, but in the following century the developments were again significant thanks in particular to Arago, Foucault, Fizeau, Loewy and the Henry brothers, working with very competent instrument builders. The French school of optics flourished at the end of the nineteenth century and during the twentieth century, thanks to Fabry, his collaborators and successors, as illustrated by Perot, Chrétien, Lyot, Danjon, Paul, Couder, Courtès, Connes, Labeyrie, Baranne and Lemaitre, among others. However, from time to time there was a trend to build instruments that were too original and with little or no future, at the expense of more conventional but better-adapted instruments.

Published
2022

17. Uptake kinetics of spontaneously emulsified microdroplets at an air–liquid interface

Author

Léa Delance, Charlotte Veillon, Nicolas Passade-Boupat, François Lequeux, Laurence Talini, and Emilie Verneuil

Subjects
General Chemistry, Condensed Matter Physics
Abstract

Understanding the transfers occurring at the interfaces between emulsions and air is required to predict the properties of foamed emulsions, used for example as antifoaming lubricants or for oil extraction. Whereas bubbling oil-in-water emulsions have been studied in details, oil-in-oil emulsions have received less attention. We consider a phase-separating mixture of three oils being Polydimethylsiloxane (PDMS), decane and cyclopentanol. PDMS is dispersed as submicrometer-sized droplets by spontaneous emulsification. In bulk, we show that the time evolution of the emulsion is driven by undelayed coalescence of the Brownian microdroplets. At the freshly created interface of an air bubble created in the emulsion, we use tensiometry measurements to investigate the uptake kinetics of PDMS-rich microdroplets at the air-liquid interface. Specifically, we evidence two mechanisms of uptake: the advection of droplets at the interface during bubble swelling, followed by their diffusion on a longer time scale. We model the growth of the PDMS-rich layer at the interface and, finally, we establish the surface energy of a thin film of PDMS-rich phase squeezed between air and liquid as a function of its thickness.

Published
2022

18. Photon correlations in the collective emission of hybrid gold-(CdSe/CdS/CdZnS) nanocrystal supraparticles

Author

Blondot, V., Gérard, D., Quibeuf, G., Arnold, C., Delteil, A., Bogicevic, A., Pons, T., Lequeux, N., Buil, S., and Hermier, J-P.

Subjects
Condensed Matter - Mesoscale and Nanoscale Physics, Mesoscale and Nanoscale Physics (cond-mat.mes-hall), FOS: Physical sciences
Abstract

We investigate the photon statistics of the light emitted by single self-assembled hybrid gold-CdSe/CdS/CdZnS colloidal nanocrystal supraparticles through the detailed analysis of the intensity autocorrelation function $g^{(2)}(\tau)$. We first reveal that, despite the large number of nanocrystals involved in the supraparticle emission, antibunching can be observed. We then present a model based on non-coherent F\"orster energy transfer and Auger recombination that well captures photon antibunching. Finally, we demonstrate that some supraparticles exhibit a bunching effect at short time scales corresponding to coherent collective emission.

Published
2023

19. Fluid gels’ dual behaviour as granular matter and colloidal glass

Author

Gabriele D'Oria, Deniz Z. Gunes, François Lequeux, Christoph Hartmann, Hans Joerg Limbach, Lilia Ahrné, and d'Oria, Gabriele

Subjects
General Chemical Engineering, General Chemistry, Food Science
Abstract

Fluid gels are jammed suspensions made of deformable particles obtained by applying shear during the sol-gel transition of a hydrocolloid. Their rheological properties have been shown to be subject to large uncertainty and to change over time undergoing an ageing process. In the present fluid gel literature, it is not known whether such ageing is due to physical ageing, formation of new ion bridges, gravitational effects, or a type of ripening. Methodologies were developed to understand and quantify the fluctuations in the rheological properties of the systems investigated, which were shown to be intrinsic to their jammed particulated microstructure and reminiscent of granular matter. In addition, the time dependent evolution of the rheological properties of fluid gels have been investigated in detail. For the first time, our work determined that the time evolution of the relaxation time is not due to the ripening of the particles, to new ion bridges, and not caused by gravity-induced effects. Our results instead suggest that is caused by physical ageing which is a behaviour reminiscent of colloidal glasses. In this regard, the present study aims not only to support future systematic rheological analysis, considering the intrinsic fluctuations and the time dependency of the rheological properties, but also serves as an aid to successfully design and scale-up industrial applications.

Published
2023

20. Marangoni destabilization of bidimensional-confined gas-liquid co-flowing streams in rectangular microfluidic channels

Author

Mattéo Clerget, Alexandra Klimenko, Maurice Bourrel, François Lequeux, Pascal Panizza, Laboratoire Physico-Chimie des Interfaces Complexes (PIC), Sciences et Ingénierie de la Matière Molle (UMR 7615) (SIMM), Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Pôle d'Etude et de Recherche de Lacq [Total] (PERL), Institut de Physique de Rennes (IPR), Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS), and Total

Subjects
Fluid Flow and Transfer Processes, Alcohol molecules, Marangoni destabilization, Microfluidics channels, Mechanical Engineering, Microfluidics, Computational Mechanics, Geometry, Molecules, Condensed Matter Physics, Reynolds number, Geometric confinement, Immiscible fluids, Mechanics of Materials, Channel height, Fluid jet, [PHYS.MECA.MEFL]Physics [physics]/Mechanics [physics]/Fluid mechanics [physics.class-ph], Co-flowing streams, Liquid CO, Stability, Gas liquids
Abstract

International audience; In microchannels, the stability of a fluid jet injected into another immiscible fluid strongly depends on its degree of geometric confinement. When the width of the jet, w, is larger than the channel height, H, the surface tension driven Rayleigh-Plateau instability is suppressed so that the 2D (bidimensional)-confined jet is absolutely stable and never collapses into bubbles (or drops) in contrast to what occurs when w ≤ H [Dollet et al., "Role of the channel geometry on the bubble pinch-off in flow-focusing,"Phys. Rev. Lett. 100(3), 034504 (2008); Guillot et al., "Stability of a jet in confined pressure-driven biphasic flows at low Reynolds number in various geometries,"Phys. Rev. E 78(1), 016307 (2008)]. We here demonstrate both experimentally and theoretically that this picture is, indeed, no longer valid when Marangoni effects are considered. We experimentally show that the addition of small length alcohol molecules into the liquid phase destabilizes a 2D-confined gas-water microfluidic stream (w > H), leading to the generation of steady non-linear waves and further to the production of bubbles. Using a simple hydrodynamic model, we show through a linear analysis that the destabilization of the gas stream may result from a Marangoni instability due to the fast adsorption of the alcohol molecules, which occurs on a timescale comparable to that of the microfluidic flow. © 2023 Author(s).

Published
2023

23. Tourismus, Deutschlernen und Neuseeland, oder Wie das Internet einen Deutschkurs veränderte. Ein Projektbericht

Author

Alm-Lequeux, Antonie

Subjects
lcsh:Language and Literature, lcsh:P
Abstract

Neuseeland ist ein beliebtes Reiseziel. Rund 60.000 Deutsche verbringen jährlich ihren Urlaub "am schönsten Ende der Welt". Andererseits ist das Land und das Leben, dem die Touristen für eine Weile im Land der großen weißen Wolke zu entkommen suchen, für viele Neuseeländer eine Reise um die Erdkugel wert. Zielpunkt eines beinahe obligatorischen "OEs" (Overseas Experience) ist oft Europa, wobei ein Abstecher nach Deutschland keine Seltenheit ist.

Published
2023

30. REMINISCENCES OF A RADIO ASTRONOMER

Author

Lequeux, James and bibliotheque, la.

Subjects
Nançay, NOEMA, History, Physics and Astronomy (miscellaneous), SEST, Parkes, Astronomy and Astrophysics, Caltech, IRAM, radio telescopes: Riese Würzburg, radio astronomy, [PHYS.ASTR] Physics [physics]/Astrophysics [astro-ph]
Abstract

The author belongs to the second generation of radio astronomers. He started observing in 1954 with a German Riese-Würzburg radar transformed into a radio telescope, then in 1959-1963 with a two- Würzburg variable-spacing interferometer. He participated in the construction of the Nançay Large Radio Telescope, and used the Owens Valley Observatory interferometer during a stay in Caltech (1968-1969). He was deeply involved in the genesis of the French-German-Spanish Institute of Radio Astronomy at Millimeter waves (IRAM). His contacts with radio astronomers worldwide are described. In recent years, he participated in a series of seven papers devoted to the history of radio astronomy in France, published in this journal.

Published
2021

31. Déstabilisation par effet Marangoni d'un jet de gaz dans un microcanal rectangulaire

Author

Panizza, Pascal, Clerget, Mattéo, Klimenko, Alexandra, Bourrel, Maurice, Lequeux, François, Institut de Physique de Rennes (IPR), and Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS)

Subjects
[PHYS]Physics [physics], [PHYS.COND.CM-SCM]Physics [physics]/Condensed Matter [cond-mat]/Soft Condensed Matter [cond-mat.soft]
Abstract

National audience

Published
2022

32. Stability of particle laden interfaces of drops flowing through a pore

Author

Franz De Soete, Nicolas Passade-Boupat, Laurence Talini, François Lequeux, and Emilie Verneuil

Subjects
Fluid Flow and Transfer Processes, Modeling and Simulation, Computational Mechanics, Soft Condensed Matter (cond-mat.soft), FOS: Physical sciences, Condensed Matter - Soft Condensed Matter
Abstract

When a drop laden with solid particles and suspended in a liquid passes through a narrow pore, its interface experiences strong shear and elongation, and the raft of particles may accumulate toward the back of the drop. Using well controlled formulations of Pickering drops driven at set pressure, we determine the two conditions for which solid particles are expelled from the oil-water interface after a Pickering drop passes a converging-diverging pore: (i) particles accumulation at the rear of the drop is such that surface pressure builds-up at the interface. (ii) Surface pressure relaxation by buckling is impaired by geometrical constraints. These two conditions are rationalized using three non dimensional numbers: the capillary number, the particle to pore size ratio, and the drop to particle size ratio, which allow to account for the viscous shear at the interface, the stability of the lubricating film between the pore wall and the drop, the drag on the raft of particles adsorbed at the interface, and its mechanical behaviour.

Published
2022

33. Synthesis and characterization of colloidal quantum dot superparticles - plasmonic gold nanoshell hybrid nanostructures

Author

Alexandra Bogicevic, Xiangzhen Xu, Stéphanie Buil, Christophe Arnold, Jean-Pierre Hermier, Thomas Pons, and Nicolas Lequeux

Abstract

Coupling an ensemble of fluorescent emitters with a plasmonic resonator opens opportunities to control their emission properties at the nanoscale. However, synthesis of such hybrid colloidal nanostructures is challenging. In this manuscript, we report the synthesis of compact assemblies of semiconductor quantum dots encapsulated into a gold nanoshell. We discuss how the synthesis parameters enable full control of the architecture of the nanostructure. Optical properties are discussed and compared to theoretical models. Coupling of the emitters to the gold layer is evidenced by an acceleration of the photoluminescence decay and results in an improvement of the photostability.

Published
2022

34. Wolbachiagenomics reveals a potential for a nutrition-based symbiosis in blood-sucking Triatomine bugs

Author

Jonathan Filée, Kenny Agésilas-Lequeux, Laurie Lacquehay, Jean Michel Bérenger, Lise Dupont, Vagner Mendonça, João Aristeu da Rosa, and Myriam Harry

Abstract

SummaryThe nutritional symbiosis promoted by bacteria is a key determinant for adaptation and evolution of many insect lineages. A complex form of nutritional mutualism that arose in blood-sucking insects critically depends on diverse bacterial symbionts that supplement the diet of their nutrient-poor hosts with B vitamins. For instance, the triatomine bugRhodnius prolixus, one of the main vectors of the Chagas disease in humans, is known to maintain a nutritional symbiosis with the gut symbiontsRhodococcus rhodnii.In this study, we show thatWolbachiasymbionts are also widely distributed in theRhodniusgenus. We have screened a large set ofRhodniusblood-sucking bugs samples belonging to 17 different species and to the three phylogenetic groups,prolixus, pallescensandpictipes. We assembled 13 genomes ofWolbachiainfecting eightRhodniusspecies fromprolixusandpictipesgroups. We demonstrate that theseWolbachiabelong to supergroup F and are closely related toWolbachiainfecting the bedbugCimex lectularius(wCle). Although bedbugs and triatomines are very distantly related hemipteran bugs, the genomes of their respectiveWolbachiawere highly similar, suggesting recent horizontal host switches. We also show thatRhodnius Wolbachiagenomes infecting theprolixusgroup encode intact biotin operon, the hallmark of nutritional symbiosis in bedbugs. This operon is lacking from all the otherWolbachiainfectingR. pictipes. Finally, host genome analyses provide evidence of massiveWolbachia-to-Rhodniusgene transfers in almost samples, providing footprints of past infections that support a widespread and probably ancient symbiotic association betweenWolbachiaand triatomine bugs.Our results suggest that bothWolbachiaandR. rhodniigut symbionts and theirRhodniushost maintain a highly prevalent symbiotic relationship, in which the vertically-inheritedWolbachiahas the metabolic potantial to ensure or complement, the nutritional mutualism provided by the gut symbionts. Specific loss of the biotin operon in some symbiont genomes suggests that the boundaries between obligatory mutualism, facultative mutualism and parasitism inWolbachiaare transient and fluid, supporting a dynamic process of transition and reversion from one state to another.

Published
2022

35. Sex‐ and age‐related differences in the management and outcomes of chronic heart failure: an analysis of patients from the ESC HFA EORP Heart Failure Long‐Term Registry

Author

Lainscak, M., Milinkovic, I., Polovina, M., Crespo-Leiro, M. G., Lund, L. H., Anker, S. D., Laroche, C., Ferrari, R., Coats, A. J. S., Mcdonagh, T., Filippatos, G., Maggioni, A. P., Piepoli, M. F., Rosano, G. M. C., Ruschitzka, F., Simic, D., Asanin, M., Eicher, J. -C., Yilmaz, M. B., Seferovic, P. M., Gale, C. P., Chair, G. B., Branko Beleslin, R. S., Andrzej Budaj, P. L., Ovidiu Chioncel, R. O., Nikolaos Dagres, D. E., Nicolas Danchin, F. R., David Erlinge, S. E., Jonathan Emberson, G. B., Michael Glikson, I. L., Alastair Gray, G. B., Meral Kayikcioglu, T. R., Aldo Maggioni, I. T., Klaudia Vivien Nagy, H. U., Aleksandr Nedoshivin, R. U., Anna-Sonia Petronio, I. T., Jolien Roos-Hesselink, N. L., Lars Wallentin, S. E., Uwe Zeymer, D. E., Crespo-Leiro, M., Anker, S., Mebazaa, A., Coats, A., A. Goda A. L., M. Diez A. R., A. Fernandez A. R., F. Fruhwald A. T., Fazlibegovic, E., P. Gatzov B. G., A. Kurlianskaya B. Y., R. Hullin C. H., T. Christodoulides C. Y., J. Hradec C. Z., O. Wendelboe Nielsen D. K., R. Nedjar D. Z., T. Uuetoa E. E., M. Hassanein E. G., J. F. Delgado Jimenez E. S., P. Harjola F. I., V, D. Logeart F. R., V. Chumburidze G. E., D. Tousoulis G. R., D. Milicic H. R., B. Merkely H. U., O'Donoghue IE, E., O. Amir I. L., A. Shotan I. L., D. Shafie I. R., M. Metra I. T., A. Matsumori J. P., E. Mirrakhimov K. G., A. Kavoliuniene L. T., A. Erglis L. V., Vataman, E., M. Otljanska M. K., E. Srbinovska Kostovska M. K., D. Cassar DeMarco M. T., J. Drozdz P. L., Fonseca, C., O. Chioncel R. O., M. Dekleva R. S., E. Shkolnik R. U., U. Dahlstrom S. E., M. Lainscak S. I., E. Goncalvesova S. K., A. Temizhan T. R., V. Estrago U. Y., G. Bajraktari X. K., Auer, J., Ablasser, K., Fruhwald, F., Dolze, T., Brandner, K., Gstrein, S., Poelzl, G., Moertl, D., Reiter, S., Podczeck-Schweighofer, A., Muslibegovic, A., Vasilj, M., Cesko, M., Zelenika, D., Palic, B., Pravdic, D., Cuk, D., Vitlianova, K., Katova, T., Velikov, T., Kurteva, T., Gatzov, P., Kamenova, D., Antova, M., Sirakova, V., Krejci, J., Mikolaskova, M., Spinar, J., Krupicka, J., Malek, F., Hegarova, M., Lazarova, M., Monhart, Z., Hassanein, M., Sobhy, M., El Messiry, F., El Shazly, A. H., Elrakshy, Y., Youssef, A., Moneim, A. A., Noamany, M., Reda, A., Dayem, T. K. A., Farag, N., Halawa, S. I., Hamid, M. A., Said, K., Saleh, A., Ebeid, H., Hanna, R., Aziz, R., Louis, O., Enen, M. A., Ibrahim, B. S., Nasr, G., Elbahry, A., Sobhy, H., Ashmawy, M., Gouda, M., Aboleineen, W., Bernard, Y., Luporsi, P., Meneveau, N., Pillot, M., Morel, M., Seronde, M. -F., Schiele, F., Briand, F., Delahaye, F., Damy, T., de Groote, P., Fertin, M., Lamblin, N., Isnard, R., Lefol, C., Thevenin, S., Hagege, A., Jondeau, G., Logeart, D., Le Marcis, V., J. -F., Ly, Coisne, D., Lequeux, B., Le Moal, V., Mascle, S., Lotton, P., Behar, N., Donal, E., Thebault, C., Ridard, C., Reynaud, A., Basquin, A., Bauer, F., Codjia, R., Galinier, M., Tourikis, P., Stavroula, M., Tousoulis, D., Stefanadis, C., Chrysohoou, C., Kotrogiannis, I., Matzaraki, V., Dimitroula, T., Karavidas, A., Tsitsinakis, G., Kapelios, C., Nanas, J., Kampouri, H., Nana, E., Kaldara, E., Eugenidou, A., Vardas, P., Saloustros, I., Patrianakos, A., Tsaknakis, T., Evangelou, S., Nikoloulis, N., Tziourganou, H., Tsaroucha, A., Papadopoulou, A., Douras, A., Polgar, L., Merkely, B., Kosztin, A., Nyolczas, N., Nagy, A. C., Halmosi, R., Elber, J., Alony, I., Shotan, A., Fuhrmann, A. V., Amir, O., Romano, S., Marcon, S., Penco, M., Di Mauro, M., Lemme, E., Carubelli, V., Rovetta, R., Metra, M., Bulgari, M., Quinzani, F., Lombardi, C., Bosi, S., Schiavina, G., Squeri, A., Barbieri, A., Di Tano, G., Pirelli, S., Fucili, A., Passero, T., Musio, S., Di Biase, M., Correale, M., Salvemini, G., Brognoli, S., Zanelli, E., Giordano, A., Agostoni, P., Italiano, G., Salvioni, E., Copelli, S., Modena, M. G., Reggianini, L., Valenti, C., Olaru, A., Bandino, S., Deidda, M., Mercuro, G., Dessalvi, C. C., Marino, P. N., Di Ruocco, M. V., Sartori, C., Piccinino, C., Parrinello, G., Licata, G., Torres, D., Giambanco, S., Busalacchi, S., Arrotti, S., Novo, S., Inciardi, R. M., Pieri, P., Chirco, P. R., Galifi, M. A., Teresi, G., Buccheri, D., Minacapelli, A., Veniani, M., Frisinghelli, A., Priori, S. G., Cattaneo, S., Opasich, C., Gualco, A., Pagliaro, M., Mancone, M., Fedele, F., Cinque, A., Vellini, M., Scarfo, I., Romeo, F., Ferraiuolo, F., Sergi, D., Anselmi, M., Melandri, F., Leci, E., Iori, E., Bovolo, V., Pidello, S., Frea, S., Bergerone, S., Botta, M., Canavosio, F. G., Gaita, F., Merlo, M., Cinquetti, M., Sinagra, G., Ramani, F., Fabris, E., Stolfo, D., Artico, J., Miani, D., Fresco, C., Daneluzzi, C., Proclemer, A., Cicoira, M., Zanolla, L., Marchese, G., Torelli, F., Vassanelli, C., Voronina, N., Erglis, A., Tamakauskas, V., Smalinskas, V., Karaliute, R., Petraskiene, I., Kazakauskaite, E., Rumbinaite, E., Kavoliuniene, A., Vysniauskas, V., Brazyte-Ramanauskiene, R., Petraskiene, D., Stankala, S., Switala, P., Juszczyk, Z., Sinkiewicz, W., Gilewski, W., Pietrzak, J., Orzel, T., Kasztelowicz, P., Kardaszewicz, P., Lazorko-Piega, M., Gabryel, J., Mosakowska, K., Bellwon, J., Rynkiewicz, A., Raczak, G., Lewicka, E., Dabrowska-Kugacka, A., Bartkowiak, R., Sosnowska-Pasiarska, B., Wozakowska-Kaplon, B., Krzeminski, A., Zabojszcz, M., Mirek-Bryniarska, E., Grzegorzko, A., Bury, K., Nessler, J., Zalewski, J., Furman, A., Broncel, M., Poliwczak, A., Bala, A., Zycinski, P., Rudzinska, M., Jankowski, L., Kasprzak, J. D., Michalak, L., Soska, K. W., Drozdz, J., Huziuk, I., Retwinski, A., Flis, P., Weglarz, J., Bodys, A., Grajek, S., Kaluzna-Oleksy, M., Straburzynska-Migaj, E., Dankowski, R., Szymanowska, K., Grabia, J., Szyszka, A., Nowicka, A., Samcik, M., Wolniewicz, L., Baczynska, K., Komorowska, K., Poprawa, I., Komorowska, E., Sajnaga, D., Zolbach, A., Dudzik-Plocica, A., Abdulkarim, A. -F., Lauko-Rachocka, A., Kaminski, L., Kostka, A., Cichy, A., Ruszkowski, P., Splawski, M., Fitas, G., Szymczyk, A., Serwicka, A., Fiega, A., Zysko, D., Krysiak, W., Szabowski, S., Skorek, E., Pruszczyk, P., Bienias, P., Ciurzynski, M., Welnicki, M., Mamcarz, A., Folga, A., Zielinski, T., Rywik, T., Leszek, P., Sobieszczanska-Malek, M., Piotrowska, M., Kozar-Kaminska, K., Komuda, K., Wisniewska, J., Tarnowska, A., Balsam, P., Marchel, M., Opolski, G., Kaplon-Cieslicka, A., Gil, R. J., Mozenska, O., Byczkowska, K., Gil, K., Pawlak, A., Michalek, A., Krzesinski, P., Piotrowicz, K., Uzieblo-Zyczkowska, B., Stanczyk, A., Skrobowski, A., Ponikowski, P., Jankowska, E., Rozentryt, P., Polonski, L., Gadula-Gacek, E., Nowalany-Kozielska, E., Kuczaj, A., Kalarus, Z., Szulik, M., Przybylska, K., Klys, J., Prokop-Lewicka, G., Kleinrok, A., Aguiar, C. T., Ventosa, A., Pereira, S., Faria, R., Chin, J., De Jesus, I., Santos, R., Silva, P., Moreno, N., Queiros, C., Lourenco, C., Pereira, A., Castro, A., Andrade, A., Guimaraes, T. O., Martins, S., Placido, R., Lima, G., Brito, D., Francisco, A. R., Cardiga, R., Proenca, M., Araujo, I., Marques, F., Moura, B., Leite, S., Campelo, M., Silva-Cardoso, J., Rodrigues, J., Rangel, I., Martins, E., Correia, A. S., Peres, M., Marta, L., da Silva, G. F., Severino, D., Durao, D., Leao, S., Magalhaes, P., Moreira, I., Cordeiro, A. F., Ferreira, C., Araujo, C., Ferreira, A., Baptista, A., Radoi, M., Bicescu, G., Vinereanu, D., Sinescu, C. -J., Macarie, C., Popescu, R., Daha, I., Dan, G. -A., Stanescu, C., Dan, A., Craiu, E., Nechita, E., Aursulesei, V., Christodorescu, R., Otasevic, P., Simeunovic, D., Ristic, A. D., Celic, V., Pavlovic-Kleut, M., Lazic, J. S., Stojcevski, B., Pencic, B., Stevanovic, A., Andric, A., Iric-Cupic, V., Jovic, M., Davidovic, G., Milanov, S., Mitic, V., Atanaskovic, V., Antic, S., Pavlovic, M., Stanojevic, D., Stoickov, V., Ilic, S., Ilic, M. D., Petrovic, D., Stojsic, S., Kecojevic, S., Dodic, S., Adic, N. C., Cankovic, M., Stojiljkovic, J., Mihajlovic, B., Radin, A., Radovanovic, S., Krotin, M., Klabnik, A., Goncalvesova, E., Pernicky, M., Murin, J., Kovar, F., Kmec, J., Semjanova, H., Strasek, M., Iskra, M. S., Ravnikar, T., Suligoj, N. C., Komel, J., Fras, Z., Jug, B., Glavic, T., Losic, R., Bombek, M., Krajnc, I., Krunic, B., Horvat, S., Kovac, D., Rajtman, D., Cencic, V., Letonja, M., Winkler, R., Valentincic, M., Melihen-Bartolic, C., Bartolic, A., Vrckovnik, M. P., Kladnik, M., Pusnik, C. S., Marolt, A., Klen, J., Drnovsek, B., Leskovar, B., Anguita, M. J. F., Page, J. C. G., Martinez, F. M. S., Andres, J., Genis, A. B., Mirabet, S., Mendez, A., Garcia-Cosio, L., Roig, E., Leon, V., Gonzalez-Costello, J., Muntane, G., Garay, A., Alcade-Martinez, V., Fernandez, S. L., Rivera-Lopez, R., Puga-Martinez, M., Fernandez-Alvarez, M., Serrano-Martinez, J. L., Grille-Cancela, Z., Marzoa-Rivas, R., Blanco-Canosa, P., Paniagua-Martin, M. J., Barge-Caballero, E., Cerdena, I. L., Baldomero, I. F. H., Padron, A. L., Rosillo, S. O., Gonzalez-Gallarza, R. D., Montanes, O. S., Manjavacas, A. M. I., Conde, A. C., Araujo, A., Soria, T., Garcia-Pavia, P., Gomez-Bueno, M., Cobo-Marcos, M., Alonso-Pulpon, L., Cubero, J. S., Sayago, I., Gonzalez-Segovia, A., Briceno, A., Subias, P. E., Hernandez, M. V., Cano, M. J. R., Sanchez, M. A. G., Jimenez, J. F. D., Garrido-Lestache, E. B., Pinilla, J. M. G., de la Villa, B. G., Sahuquillo, A., Marques, R. B., Calvo, F. T., Perez-Martinez, M. T., Gracia-Rodenas, M. R., Garrido-Bravo, I. P., Pastor-Perez, F., Pascual-Figal, D. A., Molina, B. D., Orus, J., Gonzalo, F. E., Bertomeu, V., Valero, R., Martinez-Abellan, R., Quiles, J., Rodrigez-Ortega, J. A., Mateo, I., Elamrani, A., Fernandez-Vivancos, C., Valero, D. B., Almenar-Bonet, L., Sanchez-Lazaro, I. J., Marques-Sule, E., Facila-Rubio, L., Perez-Silvestre, J., Garcia-Gonzalez, P., Ridocci-Soriano, F., Garcia-Escriva, D., Pellicer-Cabo, A., de la Fuente Galan, L., Diaz, J. L., Platero, A. R., Arias, J. C., Blasco-Peiro, T., Julve, M. S., Sanchez-Insa, E., Aured-Guallar, C., Portoles-Ocampo, A., Melin, M., Hagglund, E., Stenberg, A., Lindahl, I. -M., Asserlund, B., Olsson, L., Dahlstrom, U., Afzelius, M., Karlstrom, P., Tengvall, L., Wiklund, P. -A., Olsson, B., Kalayci, S., Temizhan, A., Cavusoglu, Y., Gencer, E., Gunes, H., Lainscak, M., Milinkovic, I., Polovina, M., Crespo-Leiro, M. G., Lund, L. H., Anker, S. D., Laroche, C., Ferrari, R., Coats, A. J. S., Mcdonagh, T., Filippatos, G., Maggioni, A. P., Piepoli, M. F., Rosano, G. M. C., Ruschitzka, F., Simic, D., Asanin, M., Eicher, J. -C., Yilmaz, M. B., Seferovic, P. M., Gale, C. P., Chair, G. B., Branko Beleslin, R. S., Andrzej Budaj, P. L., Ovidiu Chioncel, R. O., Nikolaos Dagres, D. E., Nicolas Danchin, F. R., David Erlinge, S. E., Jonathan Emberson, G. B., Michael Glikson, I. L., Alastair Gray, G. B., Meral Kayikcioglu, T. R., Aldo Maggioni, I. T., Klaudia Vivien Nagy, H. U., Aleksandr Nedoshivin, R. U., Anna-Sonia Petronio, I. T., Jolien Roos-Hesselink, N. L., Lars Wallentin, S. E., Uwe Zeymer, D. E., Crespo-Leiro, M., Anker, S., Mebazaa, A., Coats, A., A. Goda A., L., M. Diez A., R., A. Fernandez A., R., F. Fruhwald A., T., Fazlibegovic, E., P. Gatzov B., G., A. Kurlianskaya B., Y., R. Hullin C., H., T. Christodoulides C., Y., J. Hradec C., Z., O. Wendelboe Nielsen D., K., R. Nedjar D., Z., T. Uuetoa E., E., M. Hassanein E., G., J. F. Delgado Jimenez E., S., V-, P. Harjola F. I., D. Logeart F., R., V. Chumburidze G., E., D. Tousoulis G., R., D. Milicic H., R., B. Merkely H., U., O'Donoghue IE, E., O. Amir I., L., A. Shotan I., L., D. Shafie I., R., M. Metra I., T., A. Matsumori J., P., E. Mirrakhimov K., G., A. Kavoliuniene L., T., A. Erglis L., V., Vataman, E., M. Otljanska M., K., E. Srbinovska Kostovska M., K., D. Cassar DeMarco M., T., J. Drozdz P., L., Fonseca, C., O. Chioncel R., O., M. Dekleva R., S., E. Shkolnik R., U., U. Dahlstrom S., E., M. Lainscak S., I., E. Goncalvesova S., K., A. Temizhan T., R., V. Estrago U., Y., G. Bajraktari X., K., Auer, J., Ablasser, K., Fruhwald, F., Dolze, T., Brandner, K., Gstrein, S., Poelzl, G., Moertl, D., Reiter, S., Podczeck-Schweighofer, A., Muslibegovic, A., Vasilj, M., Cesko, M., Zelenika, D., Palic, B., Pravdic, D., Cuk, D., Vitlianova, K., Katova, T., Velikov, T., Kurteva, T., Gatzov, P., Kamenova, D., Antova, M., Sirakova, V., Krejci, J., Mikolaskova, M., Spinar, J., Krupicka, J., Malek, F., Hegarova, M., Lazarova, M., Monhart, Z., Hassanein, M., Sobhy, M., El Messiry, F., El Shazly, A. H., Elrakshy, Y., Youssef, A., Moneim, A. A., Noamany, M., Reda, A., Dayem, T. K. A., Farag, N., Halawa, S. I., Hamid, M. A., Said, K., Saleh, A., Ebeid, H., Hanna, R., Aziz, R., Louis, O., Enen, M. A., Ibrahim, B. S., Nasr, G., Elbahry, A., Sobhy, H., Ashmawy, M., Gouda, M., Aboleineen, W., Bernard, Y., Luporsi, P., Meneveau, N., Pillot, M., Morel, M., Seronde, M. -F., Schiele, F., Briand, F., Delahaye, F., Damy, T., de Groote, P., Fertin, M., Lamblin, N., Isnard, R., Lefol, C., Thevenin, S., Hagege, A., Jondeau, G., Logeart, D., Le Marcis, V., Ly, J. -F., Coisne, D., Lequeux, B., Le Moal, V., Mascle, S., Lotton, P., Behar, N., Donal, E., Thebault, C., Ridard, C., Reynaud, A., Basquin, A., Bauer, F., Codjia, R., Galinier, M., Tourikis, P., Stavroula, M., Tousoulis, D., Stefanadis, C., Chrysohoou, C., Kotrogiannis, I., Matzaraki, V., Dimitroula, T., Karavidas, A., Tsitsinakis, G., Kapelios, C., Nanas, J., Kampouri, H., Nana, E., Kaldara, E., Eugenidou, A., Vardas, P., Saloustros, I., Patrianakos, A., Tsaknakis, T., Evangelou, S., Nikoloulis, N., Tziourganou, H., Tsaroucha, A., Papadopoulou, A., Douras, A., Polgar, L., Merkely, B., Kosztin, A., Nyolczas, N., Nagy, A. C., Halmosi, R., Elber, J., Alony, I., Shotan, A., Fuhrmann, A. V., Amir, O., Romano, S., Marcon, S., Penco, M., Di Mauro, M., Lemme, E., Carubelli, V., Rovetta, R., Metra, M., Bulgari, M., Quinzani, F., Lombardi, C., Bosi, S., Schiavina, G., Squeri, A., Barbieri, A., Di Tano, G., Pirelli, S., Fucili, A., Passero, T., Musio, S., Di Biase, M., Correale, M., Salvemini, G., Brognoli, S., Zanelli, E., Giordano, A., Agostoni, P., Italiano, G., Salvioni, E., Copelli, S., Modena, M. G., Reggianini, L., Valenti, C., Olaru, A., Bandino, S., Deidda, M., Mercuro, G., Dessalvi, C. C., Marino, P. N., Di Ruocco, M. V., Sartori, C., Piccinino, C., Parrinello, G., Licata, G., Torres, D., Giambanco, S., Busalacchi, S., Arrotti, S., Novo, S., Inciardi, R. M., Pieri, P., Chirco, P. R., Galifi, M. A., Teresi, G., Buccheri, D., Minacapelli, A., Veniani, M., Frisinghelli, A., Priori, S. G., Cattaneo, S., Opasich, C., Gualco, A., Pagliaro, M., Mancone, M., Fedele, F., Cinque, A., Vellini, M., Scarfo, I., Romeo, F., Ferraiuolo, F., Sergi, D., Anselmi, M., Melandri, F., Leci, E., Iori, E., Bovolo, V., Pidello, S., Frea, S., Bergerone, S., Botta, M., Canavosio, F. G., Gaita, F., Merlo, M., Cinquetti, M., Sinagra, G., Ramani, F., Fabris, E., Stolfo, D., Artico, J., Miani, D., Fresco, C., Daneluzzi, C., Proclemer, A., Cicoira, M., Zanolla, L., Marchese, G., Torelli, F., Vassanelli, C., Voronina, N., Erglis, A., Tamakauskas, V., Smalinskas, V., Karaliute, R., Petraskiene, I., Kazakauskaite, E., Rumbinaite, E., Kavoliuniene, A., Vysniauskas, V., Brazyte-Ramanauskiene, R., Petraskiene, D., Stankala, S., Switala, P., Juszczyk, Z., Sinkiewicz, W., Gilewski, W., Pietrzak, J., Orzel, T., Kasztelowicz, P., Kardaszewicz, P., Lazorko-Piega, M., Gabryel, J., Mosakowska, K., Bellwon, J., Rynkiewicz, A., Raczak, G., Lewicka, E., Dabrowska-Kugacka, A., Bartkowiak, R., Sosnowska-Pasiarska, B., Wozakowska-Kaplon, B., Krzeminski, A., Zabojszcz, M., Mirek-Bryniarska, E., Grzegorzko, A., Bury, K., Nessler, J., Zalewski, J., Furman, A., Broncel, M., Poliwczak, A., Bala, A., Zycinski, P., Rudzinska, M., Jankowski, L., Kasprzak, J. D., Michalak, L., Soska, K. W., Drozdz, J., Huziuk, I., Retwinski, A., Flis, P., Weglarz, J., Bodys, A., Grajek, S., Kaluzna-Oleksy, M., Straburzynska-Migaj, E., Dankowski, R., Szymanowska, K., Grabia, J., Szyszka, A., Nowicka, A., Samcik, M., Wolniewicz, L., Baczynska, K., Komorowska, K., Poprawa, I., Komorowska, E., Sajnaga, D., Zolbach, A., Dudzik-Plocica, A., Abdulkarim, A. -F., Lauko-Rachocka, A., Kaminski, L., Kostka, A., Cichy, A., Ruszkowski, P., Splawski, M., Fitas, G., Szymczyk, A., Serwicka, A., Fiega, A., Zysko, D., Krysiak, W., Szabowski, S., Skorek, E., Pruszczyk, P., Bienias, P., Ciurzynski, M., Welnicki, M., Mamcarz, A., Folga, A., Zielinski, T., Rywik, T., Leszek, P., Sobieszczanska-Malek, M., Piotrowska, M., Kozar-Kaminska, K., Komuda, K., Wisniewska, J., Tarnowska, A., Balsam, P., Marchel, M., Opolski, G., Kaplon-Cieslicka, A., Gil, R. J., Mozenska, O., Byczkowska, K., Gil, K., Pawlak, A., Michalek, A., Krzesinski, P., Piotrowicz, K., Uzieblo-Zyczkowska, B., Stanczyk, A., Skrobowski, A., Ponikowski, P., Jankowska, E., Rozentryt, P., Polonski, L., Gadula-Gacek, E., Nowalany-Kozielska, E., Kuczaj, A., Kalarus, Z., Szulik, M., Przybylska, K., Klys, J., Prokop-Lewicka, G., Kleinrok, A., Aguiar, C. T., Ventosa, A., Pereira, S., Faria, R., Chin, J., De Jesus, I., Santos, R., Silva, P., Moreno, N., Queiros, C., Lourenco, C., Pereira, A., Castro, A., Andrade, A., Guimaraes, T. O., Martins, S., Placido, R., Lima, G., Brito, D., Francisco, A. R., Cardiga, R., Proenca, M., Araujo, I., Marques, F., Moura, B., Leite, S., Campelo, M., Silva-Cardoso, J., Rodrigues, J., Rangel, I., Martins, E., Correia, A. S., Peres, M., Marta, L., da Silva, G. F., Severino, D., Durao, D., Leao, S., Magalhaes, P., Moreira, I., Cordeiro, A. F., Ferreira, C., Araujo, C., Ferreira, A., Baptista, A., Radoi, M., Bicescu, G., Vinereanu, D., Sinescu, C. -J., Macarie, C., Popescu, R., Daha, I., Dan, G. -A., Stanescu, C., Dan, A., Craiu, E., Nechita, E., Aursulesei, V., Christodorescu, R., Otasevic, P., Simeunovic, D., Ristic, A. D., Celic, V., Pavlovic-Kleut, M., Lazic, J. S., Stojcevski, B., Pencic, B., Stevanovic, A., Andric, A., Iric-Cupic, V., Jovic, M., Davidovic, G., Milanov, S., Mitic, V., Atanaskovic, V., Antic, S., Pavlovic, M., Stanojevic, D., Stoickov, V., Ilic, S., Ilic, M. D., Petrovic, D., Stojsic, S., Kecojevic, S., Dodic, S., Adic, N. C., Cankovic, M., Stojiljkovic, J., Mihajlovic, B., Radin, A., Radovanovic, S., Krotin, M., Klabnik, A., Goncalvesova, E., Pernicky, M., Murin, J., Kovar, F., Kmec, J., Semjanova, H., Strasek, M., Iskra, M. S., Ravnikar, T., Suligoj, N. C., Komel, J., Fras, Z., Jug, B., Glavic, T., Losic, R., Bombek, M., Krajnc, I., Krunic, B., Horvat, S., Kovac, D., Rajtman, D., Cencic, V., Letonja, M., Winkler, R., Valentincic, M., Melihen-Bartolic, C., Bartolic, A., Vrckovnik, M. P., Kladnik, M., Pusnik, C. S., Marolt, A., Klen, J., Drnovsek, B., Leskovar, B., Anguita, M. J. F., Page, J. C. G., Martinez, F. M. S., Andres, J., Genis, A. B., Mirabet, S., Mendez, A., Garcia-Cosio, L., Roig, E., Leon, V., Gonzalez-Costello, J., Muntane, G., Garay, A., Alcade-Martinez, V., Fernandez, S. L., Rivera-Lopez, R., Puga-Martinez, M., Fernandez-Alvarez, M., Serrano-Martinez, J. L., Grille-Cancela, Z., Marzoa-Rivas, R., Blanco-Canosa, P., Paniagua-Martin, M. J., Barge-Caballero, E., Cerdena, I. L., Baldomero, I. F. H., Padron, A. L., Rosillo, S. O., Gonzalez-Gallarza, R. D., Montanes, O. S., Manjavacas, A. M. I., Conde, A. C., Araujo, A., Soria, T., Garcia-Pavia, P., Gomez-Bueno, M., Cobo-Marcos, M., Alonso-Pulpon, L., Cubero, J. S., Sayago, I., Gonzalez-Segovia, A., Briceno, A., Subias, P. E., Hernandez, M. V., Cano, M. J. R., Sanchez, M. A. G., Jimenez, J. F. D., Garrido-Lestache, E. B., Pinilla, J. M. G., de la Villa, B. G., Sahuquillo, A., Marques, R. B., Calvo, F. T., Perez-Martinez, M. T., Gracia-Rodenas, M. R., Garrido-Bravo, I. P., Pastor-Perez, F., Pascual-Figal, D. A., Molina, B. D., Orus, J., Gonzalo, F. E., Bertomeu, V., Valero, R., Martinez-Abellan, R., Quiles, J., Rodrigez-Ortega, J. A., Mateo, I., Elamrani, A., Fernandez-Vivancos, C., Valero, D. B., Almenar-Bonet, L., Sanchez-Lazaro, I. J., Marques-Sule, E., Facila-Rubio, L., Perez-Silvestre, J., Garcia-Gonzalez, P., Ridocci-Soriano, F., Garcia-Escriva, D., Pellicer-Cabo, A., de la Fuente Galan, L., Diaz, J. L., Platero, A. R., Arias, J. C., Blasco-Peiro, T., Julve, M. S., Sanchez-Insa, E., Aured-Guallar, C., Portoles-Ocampo, A., Melin, M., Hagglund, E., Stenberg, A., Lindahl, I. -M., Asserlund, B., Olsson, L., Dahlstrom, U., Afzelius, M., Karlstrom, P., Tengvall, L., Wiklund, P. -A., Olsson, B., Kalayci, S., Temizhan, A., Cavusoglu, Y., Gencer, E., Gunes, H., University of Zurich, and Seferović, Petar M

Subjects
Male, Registry, medicine.medical_specialty, Adverse outcomes, 610 Medicine & health, Angiotensin-Converting Enzyme Inhibitors, 030204 cardiovascular system & hematology, Independent predictor, 2705 Cardiology and Cardiovascular Medicine, Ventricular Function, Left, 03 medical and health sciences, Age, 0302 clinical medicine, Internal medicine, Age related, Hospitalization, Mortality, Sex, medicine, Humans, Registries, Medical prescription, Aged, Heart Failure, Ejection fraction, business.industry, Stroke Volume, medicine.disease, Ageing, Heart failure, 10209 Clinic for Cardiology, Female, Angiotensin Receptor Blockers, Cardiology and Cardiovascular Medicine, business
Abstract

[Abstract] Aims. This study aimed to assess age‐ and sex‐related differences in management and 1‐year risk for all‐cause mortality and hospitalization in chronic heart failure (HF) patients. Methods and results. Of 16 354 patients included in the European Society of Cardiology Heart Failure Long‐Term Registry, 9428 chronic HF patients were analysed [median age: 66 years; 28.5% women; mean left ventricular ejection fraction (LVEF) 37%]. Rates of use of guideline‐directed medical therapy (GDMT) were high (angiotensin‐converting enzyme inhibitors/angiotensin receptor blockers, beta‐blockers and mineralocorticoid receptor antagonists: 85.7%, 88.7% and 58.8%, respectively). Crude GDMT utilization rates were lower in women than in men (all differences: P ≤ 0.001), and GDMT use became lower with ageing in both sexes, at baseline and at 1‐year follow‐up. Sex was not an independent predictor of GDMT prescription; however, age >75 years was a significant predictor of GDMT underutilization. Rates of all‐cause mortality were lower in women than in men (7.1% vs. 8.7%; P = 0.015), as were rates of all‐cause hospitalization (21.9% vs. 27.3%; P < 0.001) and there were no differences in causes of death. All‐cause mortality and all‐cause hospitalization increased with greater age in both sexes. Sex was not an independent predictor of 1‐year all‐cause mortality (restricted to patients with LVEF ≤45%). Mortality risk was significantly lower in patients of younger age, compared to patients aged >75 years. Conclusions. There was a decline in GDMT use with advanced age in both sexes. Sex was not an independent predictor of GDMT or adverse outcomes. However, age >75 years independently predicted lower GDMT use and higher all‐cause mortality in patients with LVEF ≤45%.

Published
2019

36. First symptoms and health care pathways in hospitalized patients with acute heart failure: <scp>ICPS2</scp> survey. A report from the Heart Failure Working Group (GICC) of the French Society of Cardiology

Author

Barnabas Gellen, Florence Beauvais, Guillaume Baudry, Delphine Mika, Florian Zores, Théo Pezel, Damien Legallois, Chloé Motet, Charles Taieb, Lamia Tartière, Emmanuelle Berthelot, Julien Guihaire, Thibaud Damy, Frédéric Mouquet, Marie-Claude Aumont, Benoit Lequeux, Muriel Salvat, Jean-Christophe Eicher, and Michel Galinier

Subjects
Male, medicine.medical_specialty, Lower limb edema, Referral, Hospitalized patients, Clinical Investigations, Cardiology, 030204 cardiovascular system & hematology, comorbidities, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Health care, medicine, risk factors, Humans, 030212 general & internal medicine, healthcare pathway, Aged, Heart Failure, business.industry, Retrospective cohort study, Mean age, General Medicine, medicine.disease, Hospitalization, Heart failure, Acute Disease, symptoms, Cardiology and Cardiovascular Medicine, business, Delivery of Health Care, Sudden onset
Abstract

Background Acute heart failure (AHF) is a common serious condition that contributes to about 5% of all emergency hospital admissions in Europe. Hypothesis To assess the type and chronology of the first AHF symptoms before hospitalization and to examine the French healthcare system pathways before, during and after hospitalization. Material and Methods A retrospective observational study including patients hospitalized for AHF Results 793 patients were included, 59.0% were men, 45.6% identified heart failure (HF) as the main cause of hospitalization; 36.0% were unaware of their HF. Mean age was 72.9 ± 14.5 years. The symptoms occurring the most before hospitalization were dyspnea (64.7%) and lower limb edema (27.7%). Prior to hospitalization, 47% had already experienced symptoms for 15 days; 32% of them for 2 months. Referral to hospital was made by the emergency medical assistance service (SAMU, 41.6%), a general practitioner (GP, 22.3%), a cardiologist (19.5%), or the patient (16.6%). The modality of referral depended more on symptom acuteness than on type of symptoms. A sudden onset of AHF symptoms led to making an emergency call or to spontaneously attending an emergency room (ER), whereas cardiologists were consulted when symptoms had already been present for over 15 days. Cardiologists referred more patients to cardiology departments and fewer patients to the ER than general practitioners or the SAMU. Conclusion This study described the French healthcare system pathways before, during and after hospitalization AHF. AHF clinic network should be developed to provide adequate care for all HF patients and create awareness regarding AHF symptoms.

Published
2021

38. Zwitterionic Polymers towards the Development of Orientation-Sensitive Bioprobes

Author

Zijun Wang, Fanny Delille, Sophie Bartier, Thomas Pons, Nicolas Lequeux, Bruno Louis, Jongwook Kim, Thierry Gacoin, Laboratoire de physique de la matière condensée (LPMC), École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique et d'Etude des Matériaux (UMR 8213) (LPEM), Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), IMRB - 'Biomechanics and Respiratory Apparatus' [Créteil] (U955 Inserm - UPEC), Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), and Louis, Bruno

Subjects
polarization, lanthanide, Polymers, [SDV]Life Sciences [q-bio], zwitterion, Surfaces and Interfaces, Biosensing Techniques, Condensed Matter Physics, Lanthanoid Series Elements, nanorod, [SDV] Life Sciences [q-bio], bioapplication, Quantum Dots, Electrochemistry, functionalization, General Materials Science, Salts, Spectroscopy
Abstract

International audience; Dynamics with an orientational degree of freedom are fundamental in biological events. Probes with polarized luminescence enable a determination of the orientation. Lanthanide-doped nanocrystals can provide more precise analysis than quantum dots due to the non-photoblinking/bleaching nature and the multiple line-shaped emission. However, the intrinsic polarization property of the original nanocrystals often deteriorates in complex physiological environments, because the colloidal stability easily breaks and the probes aggregate in the media with abundant salts and macromolecules. Engineering the surface chemistry of the probes is thus essential to be compatible with biosystems, which has remained a challenging task that should be exclusively addressed for each specific probe. Here, we demonstrate a facile and efficient surface functionalization of lanthanide-doped nanorods by zwitterionic block copolymers. Due to the steric interaction and the intrinsic zwitterionic nature of the polymers, high colloidal stability of the zwitterionic nanorod suspension is achieved over wide ranges of pH and concentration of salts, even giving rise to the lyotropic liquid crystalline behavior of the nanorods in physiological media. The shear-aligned ability is shown to be unaltered by the coated polymers and thus the strongly polarized emission of Eu 3+ is preserved. Besides, biological experiments reveal good biocompatibility of the zwitterionic nanorods with negligible non-specific binding. This study is a stepping stone for the use of the nanorods as orientation probes in biofluids and validates the strategy of coupling zwitterions to lanthanide-doped nanocrystals for various bio-applications.

Published
2022

39. Understanding of clogging mechanisms in porous media by Pickering emulsion droplets

Author

Le Beulze, Aurélie, Santos, Nathalie, Levaché, Bertrand, Questel, Mathias, Levant, Michael, Panizza, Pascal, Lequeux, François, Passade-Boupat, Nicolas, TotalEnergies, Institut de Physique de Rennes (IPR), Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS), Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL), and Panizza, Pascal

Subjects
[PHYS.COND.CM-SCM]Physics [physics]/Condensed Matter [cond-mat]/Soft Condensed Matter [cond-mat.soft], [PHYS.COND.CM-SCM] Physics [physics]/Condensed Matter [cond-mat]/Soft Condensed Matter [cond-mat.soft]
Abstract

International audience

Published
2022

40. The role of auto-emulsification of water in oil to change the surface wettability

Author

Puentes Rivas, Duala, Klimenko, Alexandra, Santanach-Carreras, Enric, Passade-Boupat, Nicolas, Panizza, Pascal, Lequeux, François, Institut de Physique de Rennes (IPR), and Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS)

Subjects
[PHYS]Physics [physics], [PHYS.COND.CM-SCM]Physics [physics]/Condensed Matter [cond-mat]/Soft Condensed Matter [cond-mat.soft]
Abstract

National audience

Published
2022

41. Perfluoroalkylated Biomolecules for Medicinal Chemistry and Biological Studies

Author

T. Brigaud, B. Crousse, and T. Lequeux

Abstract

For many years, it has been well established that the presence of a fluorine atom and/or a fluorinated group in molecules leads to active and selective drugs for certain diseases. With developments in this field, polyfluoroalkylated compounds for nuclear magnetic resonance (19F NMR) spectroscopy and magnetic resonance imaging (19F MRI) have been intensively studied in chemical biological investigations, imaging and diagnostics.

Published
2022

42. Raw Materials strategy

Author

Veera Padmanbhan, Bijan Zakeri, Sudheer Sami, Stefan Minning, Michael DiFore, Jessica Mondia, Nathaniel Fair, Doug Berry, Chris Lyman, Laura McFadden, Veronique Deparis, Janmeet Anant, Wade Nudson, Laura Bentley, Vesna Stergar, Xiaoya Hu, Chris Wiedel, Tzu Chiang Han, Eric Shierly, Stefan Paschen, Divya Vasudevan, Elham Biouet, Sara Dorman, Fan Gao, Catherien Buchere, Benjamin Jequier, Michelle Ferreri, Nicola Coles, Lesley Holt, Jannika Kremer, and Isabelle Lequeux

Published
2022

43. Effect of the pore geometry on the foam formation at pore scale

Author

Clerget, Mattéo, Klimenko, Alexandra, Chandrasekhar, Vivaswan, Bourrel, Maurice, Panizza, Pascal, Lequeux, François, TotalEnergies SE, Laboratoire Physico-Chimie des Interfaces Complexes (PIC), Sciences et Ingénierie de la Matière Molle (UMR 7615) (SIMM), Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Ecole Superieure de Physique et de Chimie Industrielles de la Ville de Paris (ESPCI Paris), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut de Chimie du CNRS (INC)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Institut de Physique de Rennes (IPR), Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS), Gordon Research Conference, and Panizza, Pascal

Subjects
[PHYS]Physics [physics], [PHYS] Physics [physics]
Abstract

International audience

Published
2022

44. Mechanisms ruling the lifetimes of films of liquid mixtures

Author

H.-P. Tran, N. Passade-Boupat, F. Lequeux, and L. Talini

Subjects
Mechanics of Materials, Mechanical Engineering, Applied Mathematics, Condensed Matter Physics
Abstract

Foams and bubbles formed in liquid mixtures have lifetimes longer by several orders of magnitude than in pure liquids of similar viscosities. We have shown recently that this effect results from slight differences in molecular concentrations between bulk and surfaces, which give rise to a thickness-dependent surface tension of liquid films. We present a quantitative description of the enhanced stability of liquid films in binary mixtures, based on experimental data and theoretical analysis. Experiments were performed with mixtures of different natures and compositions: foams of stationary heights were obtained by continuous injection of gas, on one hand, and single bubbles were swollen under the surface of a liquid bath, on the other hand. Remarkably, the lifetimes measured in both experiments exhibit the same variations with mixture composition, and follow a power law with the microscopic length that characterises the amplitude of the thickness-dependent surface tension. In addition, the lifetimes vary with the squared film thicknesses at the onset of bursting. We suggest that two stages occur between the birth of liquid films and their rupture. We show how the thickness-dependent surface tension allows an equilibrium shape to be reached at the end of a first stretching stage. We give an analytical description of this shape, which is fully consistent with experimental findings. We suggest a possible mechanism for final rupture of the film, and discuss it in light of existing theoretical predictions. Finally, we compare the properties of liquid mixtures and surfactant solutions, and in particular their surface rheology.

Published
2022

46. Off-axis electron holography for the direct visualization of perpendicular shape anisotropy in nano-scale 3D magnetic random-access-memory devices

Author

Trevor P. Almeida, Alvaro Palomino, Steven Lequeux, Victor Boureau, Olivier Fruchart, Ioan Lucian Prejbeanu, Bernard Dieny, David Cooper, Commissariat à l'énergie atomique et aux énergies alternatives - Laboratoire d'Electronique et de Technologie de l'Information (CEA-LETI), Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), SUPA School of Physics and Astronomy [Glasgow], University of Glasgow, SPINtronique et TEchnologie des Composants (SPINTEC), Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA), Interdisciplinary Center for Electron Microscopy (CIME) Ecole Polytechnique Fédérale de Lausanne, Ecole Polytechnique Fédérale de Lausanne (EPFL), Institut Carnot, and European Project: 669204,H2020,ERC-2014-ADG,MAGICAL(2015)

Subjects
spintronics, Condensed Matter - Mesoscale and Nanoscale Physics, summation, Mesoscale and Nanoscale Physics (cond-mat.mes-hall), General Engineering, [PHYS.COND.CM-MS]Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci], FOS: Physical sciences, tunnel-junctions, General Materials Science, stability
Abstract

Perpendicular shape anisotropy (PSA) and double magnetic tunnel junctions (DMTJ) offer practical solutions to downscale spin-transfer-torque Magnetic Random-Access Memory (STT-MRAM) beyond 20 nm technology nodes, whilst retaining their thermal stability and reducing critical currents applied. However, as these modern devices become smaller and three-dimensionally (3D) complex, our understanding of their functional magnetic behavior is often indirect, relying on magnetoresistance measurements and micromagnetic modelling. In this paper, we review recent work that was performed on these structures using a range of advanced electron microscopy techniques, focusing on aspects specific to the 3D and nanoscale nature of such elements. We present the methodology for the systematic transfer of individual SST-MRAM nano-pillars from large-scale arrays to image their magnetic configurations directly using off-axis electron holography. We show that improved phase sensitivity through stacking of electron holograms can be used to image subtle variations in DMTJs and the thermal stability of < 20 nm PSA-STT-MRAM nano-pillars during in-situ heating. The experimental practicalities, benefits and limits of using electron holography for analysis of MRAM devices are discussed, unlocking practical pathways for direct imaging of the functional magnetic performance of these systems with high spatial resolution and sensitivity., 22 pages, 7 figures

Published
2022

47. Swine Breeding in the Villages of Vâlcea County, Oltenia (Romania)—Tradition or Necessity?

Author

Camelia Teodorescu, Marin Burcea, Ana-Irina Lequeux-Dincă, Florentina-Cristina Merciu, Adrian-Nicolae Jipa, and Laurenţiu-Ştefan Szemkovics

Subjects
Plant Science, Agronomy and Crop Science, Food Science
Abstract

Food supply has been a constant source of concern for mankind. In the present context, with food security a priority of European and national policies, an analysis of pig farming in a representative NUTS2 administrative level of Romania that emphasizes the proportion of households raising at least one pig and the main factors influencing farmers to adopt or give up swine breeding could allow a much clearer understanding of this phenomenon that lies at the border between cultural tradition and socio-economic necessity. This study uses mixed methods that complement each another to help reveal this complex phenomenon in the analyzed territory. Cluster analysis shows the concentration of swine breeding and maps its spread in terms of both subsistence and larger farms, and qualitative interviews prove the motivation of farmers to continue in this occupation. As a primary result, the study visualizes the spatial distribution of pig farming in the rural environment of Vâlcea county, Romania, from a diachronic perspective in the post-communist period. It also reveals areas of differing concentrations of both very small-sized farms, which prioritize meeting their own food needs, and larger farms, which prioritize commercial production to supplement their revenue streams. Both categories, but particularly the latter, are of particular interest in a period in which the socio-economic environment after 1990—marked by economic restructuring, unemployment, population migration, the economic crisis of 2008–2010, the pandemic of 2020–2021, and the most recent energy crisis—periodically highlights the importance of rural areas in ensuring food security and sufficiency at both the local and regional levels.

Published
2023

48. Le dépistage visuel chez l’enfant : les recommandations de l’Association Francophone de Strabologie et d’Ophtalmologie Pédiatrique (AFSOP)

Author

M.-A. Espinasse Berrod, S. Defoordt-Dhellemmes, F. Audren, D. Thouvenin, V. Daien, Pascal Dureau, C. Couret, Pierre Lebranchu, S. Leruez, C. Speeg-Schatz, D. Denis, L. Lequeux, Camille Costet, E. Bui-Quoc, and S. Arsene

Subjects
03 medical and health sciences, Ophthalmology, 0302 clinical medicine, 030221 ophthalmology & optometry
Abstract

Resume A l’ere du photo depistage, une actualisation des recommandations sur les methodes de depistage visuel chez l’enfant devenait necessaire. Nous exposons dans cet article les recommandations etablies suite au travail d’un groupe d’experts de l’AFSOP en fevrier 2019. Les enfants a risque de developper une amblyopie organique precoce doivent beneficier d’un examen ophtalmologique au cours du premier mois de vie. Les enfants a risque de developper une amblyopie fonctionnelle doivent beneficier d’un examen ophtalmologique avec mesure de la refraction sous cycloplegie entre l’âge de 12 et 15 mois. A tout âge, un enfant presentant des signes d’appel de pathologie oculaire ou des signes fonctionnels doit beneficier d’un examen ophtalmologique dans un delai rapide. Pour les enfants ne presentant ni facteur de risque ni signe d’appel, un examen de depistage systematique doit etre realise par un orthoptiste entre l’âge de 3 et 4 ans. Cet examen doit comprendre une mesure de l’acuite visuelle, un test a l’ecran et une mesure de la refraction par appareil de photo depistage. L’enfant est adresse a l’ophtalmologiste uniquement en cas d’anomalie a l’examen de depistage, selon les criteres suivants : acuite visuelle +2,5 D pour la sphere, > 1,5 D pour l’astigmatisme et > 1 D d’anisometropie. Enfin, une mise au point sur les normes refractives de l’enfant en fonction de l’âge et les conditions d’utilisation des appareils de photo depistage est egalement realisee.

Published
2021

49. Direct observation of the perpendicular shape anisotropy and thermal stability of STT-MRAM nano-pillars examined by off-axis electron holography

Author

David Cooper, Aurélien Massebouef, Olivier Fruchart, Ioan Lucian Prejbeanu, Richard Sousa, Steven Lequeux, Bernard Dieny, Alvaro Palomino, Trevor Almeida, N. Caçoilo, Commissariat à l'énergie atomique et aux énergies alternatives - Laboratoire d'Electronique et de Technologie de l'Information (CEA-LETI), Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), SPINtronique et TEchnologie des Composants (SPINTEC), Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA)

Subjects
[PHYS]Physics [physics], Magnetoresistive random-access memory, Materials science, Condensed matter physics, Nano, Direct observation, Perpendicular, Thermal stability, Anisotropy, Instrumentation, Electron holography
Published
2021

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