Search

Purpose: Sparc/osteonectin, cwcv, and kazal-like domains proteoglycan 1 (SPOCK1) has been found in a variety of malignant tumors and is associated with a poor prognosis. We aimed to explore the role of SPOCK1 in ovarian cancer. Methods: Ovarian cancer cell lines SKOV3 and SW626 were transfected with SPOCK1 overexpressing or empty vector using electroporation. Cells were studied by immunostaining and an automated Western blotting system. BrdU uptake and wound healing assays assessed cell proliferation and migration. SPOCK1 expression in human ovarian cancer tissues and in blood samples were studied by immunostaining and ELISA. Survival of patients with tumors exhibiting low and high SPOCK1 expression was analyzed using online tools. Results: Both transfected cell lines synthesized different SPOCK1 variants; SKOV3 cells also secreted the proteoglycan. SPOCK1 overexpression stimulated DNA synthesis and cell migration involving p21CIP1. Ovarian cancer patients had increased SPOCK1 serum levels compared to healthy controls. Tumor cells of tissues also displayed abundant SPOCK1. Moreover, SPOCK1 levels were higher in untreated ovarian cancer serum and tissue samples and lower in recipients of chemotherapy. According to in silico analyses, high SPOCK1 expression was correlated with shorter survival. Conclusion: Our findings suggest SPOCK1 may be a viable anti-tumor therapeutic target and could be used for monitoring ovarian cancer.

A collection of the materials and reports relevant to the development of a Markers of Adulthood Scale model adapted for use in the EAMMi3 project.

Previous research suggested that the more individuals feel pressured not to experience negative emotions, the more they felt loneliness (Bastian, Koval, Erbas, Houben, Pe & Kuppens, 2015) and the higher levels of negative emotions and the lower well-being they reported (Bastian, Kuppens, Hornsey, Park, Koval & Uchida, 2012). These findings suggest that the more individuals perceived that they should not experience negative emotions, the lower levels of well-being or happiness they experience. Even though preceding research findings shed a light on when individuals have a stronger association between their perceived pressure not to experience negative emotions and levels of well-being, a good overview of when and how perceived pressure not to experience negative emotions is related to well-being is still lacking. Especially not enough research has been done in how emotion regulation or view on emotions could play a role in the association between perceived societal norm on disapproval of negative emotions and well-being. Our first aim was to replicate previous finding that the more individuals think that society disapprove negative emotions, the lower levels of well-being they experience. Second, as an extension of our first aim, we investigated whether the association between perceived societal disapproval on negative emotion and well-being varies across different cultures namely Australia, South Korea and Poland. As our third aim, we explored how views on emotion (malleability of emotion) and emotion regulation strategies (reappraisal, suppression, help-seeking) are related with perceived pressure not to experience negative emotion, well-being. In investigating these associations, as our fourth aim, we also explored whether these associations differ across cultures. Overall, multiple series of analyses for these four research aims revealed as follow; First, the more individuals perceived that their society does not approve negative emotions, the lower levels of well-being they experienced. Second, this association between perceived pressure not to experience negative emotions and well-being did not differ across countries. Third, (a) reappraisal, help-seeking and belief on malleability of emotions were positively associated with well-being and (b) negatively associated with perceived pressure not to experience negative emotions. In contrast, (c) suppression was negatively associated with levels of well-being while (d) positively correlated with perceived pressure not to experience negative emotions. Fourth, even though there was no noticeable systematic cultural difference in how views on emotions and emotion regulation strategies were associated with well-being, we found an interesting cultural difference in how suppression is associate with well-being; suppression was negative related with well-being in Australia and Poland but this association was not significant in South Korea. In addition the strength of (negative) association between suppression and well-being was significantly stronger in Australia then in South Korea. This goes in line with previous literature that emotion regulation plays different role across socio-cultural contexts (Kalokerinos, Greenaway, & Casey, 2017). In addition, we conducted an additional research examining whether how views on emotion (malleability of emotion) and emotion regulation strategies (reappraisal, suppression, help-seeking) moderate or mediate the association between perceived social disapproval on negative emotions and depressive symptoms. Our analyses, in line with previous findings, showed that when negative emotions is perceived to be disapproved by the society, individuals experience more severe levels of depressive symptoms. Furthermore, this research revealed individuals, who perceive emotions malleable or who actively deal with their negative emotions by reappraise them or ask help to others to deal with their emotions, not only have lower levels of depressive symptoms but also have less impact of perceived pressure not to experience negative emotions (SEDAS) on depressive symptoms. All in all, this research suggest that it is crucial to face negative emotions and actively find ways to deal with them instead of feeling pressured not to experience them or suppress them.

본 연구는 부모 학력과 경제 수준이 청소년의 사교육 참여시간과 학업 스트레스를 순차적으로 매개하여 주관적 행복감에 미치는 영향을 직렬다중매개모형으로 분석하였다. 분석에는 한국방정환재단과 연세대학교 사회발전연구소에서 제공하는 한국 어린이 행복지수 데이터(KWCI)의 2019년 중·고등학생 5,094명의 자료를 사용하였다. 분석 결과, 첫째, 부모 학력과 경제 수준이 주관적 행복감에 미치는 영향을 사교육 시간과 학업 스트레스가 각각 유의하게 단순 매개하였다. 둘째, 부모 학력, 경제 수준과 주관적 행복감의 관계에서 사교육 시간과 학업스트레스의 유의한 순차적 매개효과도 확인하였다. 즉, 부모의 교육 수준과 경제적 수준이 높을수록 자녀의 사교육 참여시간이 늘어나고 이는 학업 스트레스에 정적으로 영향을 미치며 청소년의 주관적 행복감에 부적인 영향을 미쳤다. 본 연구에서는 청소년의 행복감과 밀접한 관련이 있는 부모 및 가정 특성, 사교육, 학업 스트레스의 관계를 통합적으로 살펴본 것에 의의가 있다.

The purpose of this study is to analyze how university students" leisure has changed before and after COVID-19, and whether leisure motivation and health belief have influenced leisure change. For this, data were collected from 235 university students in the Seoul and Gyounggi area. The research results analyzed through cross-analysis and hierarchical logistic regression are as follows. First, there were differences in leisure of university students before and after COVID-19. Compared to before, sports participation activities, cultural and arts viewing activities decreased, and recreational activities increased significantly. Based on the research results, the characteristics of leisure change of university students after COVID-19 can be called "game and media". Second, physical leisure motivation and social leisure motivation have been associated with changes in leisure of university students since COVID-19. Third, perceived benefit of health beliefs has influenced the leisure change of university students after COVID-19. Fourth, physical leisure motivation and perceived susceptibility of health belief showed an interaction effect on leisure changes of university students after COVID-19.

The Noah Land Surface Model (Noah LSM) with version 3.4.1 was developed on 18 September 2012. The current version of the off-line Noah LSM is available from the website:https://ral.ucar.edu/solutions/products/unified-noah-lsm. The genetic algorithm (GA) was developed by David L. Carroll and was last updated on 2 April 2001. The exactversion we used is version 1.7aand archiveshere. The current version 1.7.1b of the GA with minor comment updates on 2 December 2020 is available from the website:https://cuaerospace.com/products-services/genetic-algorithm/ga-drive-free-download. The forcing data and output files of Noah LSM and micro-GA-Noah LSM coupled system and the scripts to plot the same figures as the manuscript are alsoincluded.&nbsp

본 연구는 초등학생의 인지적, 정서적 공감과 또래괴롭힘 방어행동 간 관계가 지각된 교사 개입정도에 따라 달라지는지 알아보기 위해 실시되었다. 이를 위해 2017년 6, 7월 초등학교 4학년 아동 229명(남: 89명, 여: 140명)의 자기보고식 설문자료를 수집하여 남녀 집단 별로 위계적 회귀분석을 하였다. 그 결과, 남녀 모두 인지적 공감이 높은 것이 방어행동의 증가와 관련이 있었고, 특히 여학생의 경우, 교사가 또래괴롭힘에 적극적으로 개입하고 그러한 능력이 있다고 지각할 경우에만 인지적 공감과 방어행동의 관계가 유지되었다. 한편 남녀 모두에서 정서적 공감은 방어행동을 예측하지 않았고, 교사 개입정도 역시 그 자체로는 방어행동을 예측하지 않았다. 마지막으로, 이러한 결과에 기초하여 초등학생의 또래괴롭힘 방어행동을 늘리기 위한 효과적 개입방법에 대해 논의하였다.

본 연구의 목적은 경로당을 이용하는 고령후기 노인들의 생활을 분석하고, 이를 바탕으로 활동적 노년의 실현 방안을 제시하는 것이다. 현상학적 연구방법(심층인터뷰·참여/비참여 관찰·필드노트 작성)을 활용하여 서울의 경로당을 이용하고 있는 80세 이상의 노인 8명을 연구 참여자로 선정했다. 수집된 자료는 Colaizzi의 현상학적 분석방법으로 6가지의 구체적 단계를 거쳤다. 연구결과, 고령후기 노인의 특성으로 총 14개의 주제와 6개의 주제묶음이 도출되었다. 6개의 주제묶음은 , , , , , 이다. 이 결과를 바탕으로 고령후기 노인의 관점에서 실현 가능한 활동적 노년은 ‘경로당’을 이용하는 것으로, 모든 고령후기 노인들로 하여금 ‘가고 싶은’ 곳으로 재정비가 필요하다. 고령후기 노인의 활동적 노년 실현 방안으로 첫째, ‘참여’는 고령후기노인들의 체력적인 한계와 건강관리에 초점을 둔 전통문화 세대교류 프로그램 및 자원봉사 참여로 실천한다. 둘째, ‘건강’은 고령후기 노인에게 적합한 와식·좌식·입식체조와 보다 확장된 건강 체크를 실천한다. 셋째, ‘안전’은 안전한 보행훈련·치매예방관리운동·심리치료 및 안전한 죽음을 위한 준비 교육을 실시한다. 넷째, 경로당의 재정비 및 인력배치를 위한 과감한 투자와 정책 시행이 요구된다.

The goal of this study is to examine whether the genre characteristics of newspaper articles are appropriately reflected in Korean language textbooks. For the purpose of this study, two corpora were built with 17 textbook articles and 60 newspaper articles respectively. The average sentence length and frequency of vocabulary in each corpus were measured. It was found that the sentences of articles in textbooks tended to have longer sentence length and more complicated structures than the articles in newspapers. For instance, sentences in the textbook articles had more verbal endings, such as conjunctive and transforming endings. On the other hand, in case of vocabulary representing `timeliness`, there was a high frequency of adverbs and nouns which were related to year, month, and time in actual articles, while it is found to be very limited in textbooks. Also, typical translative styles such as `-ko itta`, `-e ttareumyun` were more prominent in textbooks than in newspaper articles. In the case of abbreviated and omitted form of particles, this was a characteristic that appeared only in actual articles because of the constraint of space. It is significant that this paper offers suggestions for the development of reading materials for Korean language education by revealing that the genre typology of actual newspaper articles is not adequately reflected in current textbooks. (University of Seoul·Korea University·University of Malaga)

이 연구는 한국어 모어 화자들이 장르를 구별하는 데 사용하는 언어학적 단서를 밝히는 것을 목적으로 한다. 이를 통해 한국어 읽기교육 자료를 개발하는 데 필요한 정보를 제공하고자 한다. 본 연구는 한국어 고급 교재에서 가장 빈번하게 다루어지는 장르인 설명문, 뉴스기사, 칼럼, 비평을 연구 범위로 제한하였다. 연구를 위해 각 장르에 속하는 실제 텍스트와 교재 내 읽기 텍스트 샘플 총 8개를 선정한 뒤 이를 활용하여 질문지를 작성하였다. 한국인 대학생 10명을 대상으로 질문지에 주어진 텍스트의 장르를 판별하고, 자신이 장르를 구별하는 데 활용한 장르 관련 지식이 무엇인지 답해 줄 것을 요청하였다. 조사 결과, 응답자들은 실제 텍스트의 설명문과 뉴스기사(제보적 텍스트)는 정확히 판별했지만 칼럼과 비평(호소적 텍스트)은 구별하는 데 어려움을 겪었다. 또한 한국어 교재에서 추출한 텍스트에 대해서는, 각 교재에서 명시하고 있는 장르와 일치한 응답을 한 응답자가 거의 없어, 교재 텍스트의 장르성을 높여야 함을 시사하였다. 응답자들이 장르 판별에 활용한 언어학적 요소는 글의 제목 형태, 정보 제시 방법, 텍스트 구조, 문체 등이 주를 이루었다. 지금까지 장르 연구는 주로 코퍼스 분석에 의존해 왔다. 그러나 본 연구는 언어 사용자의 장르 판별 과정을 관찰함으로써 화자 내면의 장르인식을 재구성하고자 하였다.

Immigrant children tend to be at higher risk for dissatisfactory peer relationships, often experiencing loneliness and isolation emanating from the frustrations related to struggles with negative socialization. Art Therapy counseling sessions were designed to address these children’s peer interactions and build a reciprocal therapeutic relationship for deep artistic engagements. The brief art therapy interventions with three Korean children from immigrant families outlined in this article, explored issues related to their acculturative social challenges and meaningful interpersonal interactions. The therapeutic value of their deep artistic engagements sustained through reciprocal therapeutic interactions, helped these young people to cope with social isolation and loneliness, and ultimately to form healthy peer relationships for the future. Keywords: Immigrant children, social isolation, loneliness, art therapy, reciprocal therapeutic interaction, Art Therapy Online, Vol 8 No 1 (2017): International Art Therapy Conference Proceedings