1. Osteomyelitis of the jaw: time to rethink the bone sampling strategy?
- Author
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Taieb, Guillaume, Duran-Peña, Alberto, Moulignier, Antoine, Thouvenot, Eric, Allou, Thibaut, Lacour, Arnaud, Hoang-Xuan, Khê, Pelletier, Jean, Labauge, Pierre, Bertrand, Kevin, Lamy, Brigitte, de Boutray, Marie, Yachouh, Jacques, Galmiche, Sophie, Leprêtre, Pierre, Menjot De Champfleur, Nicolas, Reynes, Jacques, Le Moing, Vincent, Morquin, David, Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Service d'ORL et chirurgie cervico-faciale, Université Montpellier 1 (UM1)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Département de Neuroradiologie[Montpellier], Université Montpellier 1 (UM1)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Hôpital Gui de Chauliac [Montpellier]-Université de Montpellier (UM), Laboratoire Charles Coulomb (L2C), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Recherches Translationnelles sur le VIH et les maladies infectieuses endémiques er émergentes (TransVIHMI), Université Cheikh Anta Diop [Dakar, Sénégal] (UCAD)-Institut de Recherche pour le Développement (IRD)-Université de Yaoundé I-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Université Montpellier 1 (UM1), Département d'anesthésie-réanimation[Montpellier], Université Montpellier 1 (UM1)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Hôpital Gui de Chauliac [Montpellier], Département de neurologie [Montpellier], Service de Neurologie [CHU Pitié-Salpêtrière], IFR70-CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Fondation Rothschild, Centre Hospitalier Universitaire de Nîmes (CHU Nîmes), Hôpital Roger Salengro [Lille], Biologie des Interactions Neurones / Glie, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de résonance magnétique biologique et médicale (CRMBM), Assistance Publique - Hôpitaux de Marseille (APHM)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), GHU Garemeau-Nîmes, Service de neurologie 1 [CHU Pitié-Salpétrière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Pitié-Salpêtrière [AP-HP], and Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU)
- Subjects
0301 basic medicine ,Male ,Biopsy ,Dentistry ,Standard procedure ,0302 clinical medicine ,Medical microbiology ,Risk Factors ,Neoplasms ,CLIPPERS ,Medicine ,Sampling (medicine) ,Child ,Blood-brain barrier ,Aged, 80 and over ,Osteomyelitis ,General Medicine ,Bacterial Infections ,Middle Aged ,3. Good health ,Stratified sampling ,Infectious Diseases ,Female ,Microbiology (medical) ,Adult ,medicine.medical_specialty ,Adolescent ,Sample (material) ,030106 microbiology ,Sampling strategy ,Bone and Bones ,Curvilinear enhancement ,03 medical and health sciences ,Young Adult ,Surgical site ,Oral and maxillofacial pathology ,Humans ,Saliva ,Aged ,Retrospective Studies ,Bacteria ,business.industry ,[SCCO.NEUR]Cognitive science/Neuroscience ,Linear enhancement ,Bacteriological diagnosis ,030206 dentistry ,medicine.disease ,Jaw ,Punctate enhancement ,business ,Tomography, X-Ray Computed - Abstract
International audience; This work aims at describing the diversity of osteomyelitis of the jaw (OJ) and at assessing the relevance of a new method designed to avoid salivary contamination during bone sampling in order to improve microbiological analysis and clinical decision-making. We reviewed medical and microbiological data of patients with a suspected OJ based on clinical and/or CT-scan signs and at least one bone sample made for microbiological analysis. During the study period, a new procedure for intraoral bone sampling was elaborated by surgeons and infectious diseases specialists authoring this article (based on stratified samples, cleaning of the surgical site and change of instruments between each sample). A comparison of the microbiological analyses between the two procedures was performed. From 2012 to 2017, 56 patients were included. Median age was 58 years (11-90), sex ratio: 1.24. Main risk factors were having a dental disease (n = 24) or cancer (n = 21). Nineteen patients with the new sample procedure were compared to 37 patients with standard procedure, especially non-cancer patients (n = 16 and 19, respectively). With the new procedure, a median of 3 (1-7) microorganisms per sample was recovered, vs. 7 (1-14) with the former (p
- Published
- 2017