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Tree growth, along with soil properties, is greatly affected by forest management. We used a typical sampling to study the impact of four thinning intensities (T1: 0%, 2500 stems ha−1; T2: 20%, 2010 stems ha−1; T3: 30%, 1750 stems ha−1; T4: 40%, 1500 stems ha−1) on the tree growth and soil physicochemical properties and their correlation in Cunninghamia lanceolata plantations. The average annual increments in tree height, diameter at breast height (DBH), and volume increased with thinning intensity, and those of T4 differed significantly (P < 0.05) from those of T1. The average annual stand volume increments of T4 were significantly (P < 0.05) lower than that of T1, while the maximum value presented at T3. However, the effect of thinning in promoting the growth of Chinese fir diminished with time. As the thinning intensity increased, the diameter class distribution of the sample stands moved rightwards. Moreover, thinning improved soil physiochemical properties. The effects of thinning on soil properties in 0–20 cm soil layer were greater than those in 20–40 cm soil layer. There was a positive correlation between available nitrogen, available potassium and tree growth. The results of this study showed that thinning had a potential effect on tree growth and soil properties. The heavy thinning intensity (approximately 1500 stems ha−1) was the optimum for maintaining economic and ecological benefits. However, heavy thinning significantly reduced stand volume. From the perspective of improving stand volume and biomass, a moderate thinning intensity (approximately 1750 stems ha−1) could be considered for adoption.

Figure S1. Knockdown of CCDC106 enhances cell apoptosis in the cells with wtp53 (HeLa, MCF7), but not the cells with mtp53 (C33A). Figure S2. Knockdown of CCDC106 does not affect p53 stability, apoptosis, growth, migration and invasion of C33A cells with mtp53. Figure S3. CX-4945 does not affect the expression of CK2ι and CK2β. Figure S4. Mutation of S130 or S147 of CCDC106 protein suppresses CCDC106-dependent degradation of the p53 protein. Figure S5. Overexpression of CCDC106, but not mutant CCDC106, reduces cell apoptosis in the cells with wtp53 (HBL100, SiHa), but not the cells with mtp53 (MDA-MB-231). Figure S6. Overexpression of CCDC106 does not affect p53 stability, apoptosis, growth, migration and invasion of MDA-MB-231 cells with mtp53. (DOC 18895 kb)

Hiroshiinoueana wuzhishanica Fei & Yu, sp. nov. (Figs. 1, 2, 4) Type. Holotype: &male;, China, Hainan Province, Mt. Wuzhi, 18��86' N, 109��67' E, 700 m, 10 Apr 2013, leg. Yinghui Sun, Wei Guan & Tengteng, Liu, genitalia slide no. LKL13264. Diagnosis. This new species is similar to H. gangweonensis in male genitalia. It can be separated from the latter species by the straight gnathos, the folded valva with the sacculus longer than the cucullus and extending to the median part of the cucullus, and the length of bristle cluster of the sacculus, which is about equal to or longer than the cucullus. In H. gangweonensis the gnathos is curved, the valva is not folded lengthwise, the sacculus is not expanded and is shorter than the cucullus, and the bristle cluster is shorter than the cucullus but longer than the sacculus. Hiroshiinoueana wuzhishanica can be easily distinguished from H. inequivalva and H. stellifera by the relatively narrow tegumen and the identical bristle clusters on the left and right sacculus in the male genitalia. In addition, the cucullus is somewhat crescent-shaped in this new species, whereas the cucullus is broad and rounded in H. inequivalva and triangular in H. stellifera Kawabe; the dorso-basal spiny lobe of the valva is rounded in H. wuzhishanica, whereas it is narrow and elongate in H. inequivalva. Description. Adult (Fig. 1). Head: Vertex rough scaled, brown suffused with pale brown. Antenna brown, with scattered dark brown scales. Labial palpus porrect, brown mixed with pale brown; median segment expanded ventrally. Thorax: Pale brown suffused with yellowish brown, with scattered metallic-blue spots; posterior crest inconspicuous. Hind tibia in male not enlarged, bearing long black scales on inner surface of basal half (Fig. 2). Forewing length 6.5 mm; elongate and triangular, costa slightly arched, apex blunt; upperside ground color dark brown, with metallic blue spots throughout, pattern elements dark brown and inconspicuous; most costal strigulae inconspicuous, covered by metallic spots, striae from strigulae 3���7 indistinct, extending toward to dorsum and tornus; fringe dark brown; underside pale brown, area of overlap with hindwing paler. Hindwing upperside pale grayish brown, costa white, anal roll present and with long white scales inside; fringe pale grey; underside pale tawny. Abdomen: Male genitalia (Fig. 4) weakly sclerotized. Tegumen broad, rounded posteriorly. Uncus small, somewhat semicircular, hairy distally. Socius laterally plate-like, densely spined. Gnathos simple, represented by two straight, narrow, lateral bands. Valvae symmetrical; basal excavation distinct; each valva folded longitudinally, sacculus covered partly by cucullus and a large densely spiny lobe protruding inward from base of cucullus, somewhat rectangular and rounded, distinctly broader and slightly shorter than cucullus, with ventral edge adjacent to cucullus concave and aciculate, spines on lobe short and strong, pointing towards phallus; cucullus narrow, somewhat crescent-shaped, spiny; sacculus broad and long, apical part reaching about mid-length of cucullus, bearing a cluster of long bristles outside of mid-length of ventral edge, which is equal in length to sacculus and longer than cucullus. Anellus well sclerotized, large, broadly surrounding phallus; phallus simple, moderate, narrowed to distal end, pointed apically, without cornuti. Vinculum simple, slightly broadened. Female unknown. Molecular characterization. Partial mitochondrial gene COI sequence with GenBank accession number MG983839. The DNA barcode sequences for this and the species described below are the first barcode data for the genus Hiroshiinoueana submitted to GenBank. Etymology. The specific name is from the type locality, Mt. Wuzhi, Hainan Province., Published as part of Fei, Yao, Zhao, Jingxia, Liu, Kaili & Yu, Haili, 2018, First record of Hiroshiinoueana Kawabe, 1978 from China (Lepidoptera: Tortricidae: Olethreutinae), with descriptions of two new species, pp. 324-330 in Zootaxa 4429 (2) on pages 325-327, DOI: 10.11646/zootaxa.4429.2.7, http://zenodo.org/record/1284031

Hiroshiinoueana Kawabe, 1978 Hiroshiinoueana Kawabe, 1978: 177. Type species: Hiroshiinoueana stellifera Kawabe, 1978, by original designation. Species of Hiroshiinoueana are medium-sized moths, often characterized by conspicuous metallic spots on the forewing. Similar markings are present in species of Gatesclarkeana Diakonoff and Ukamenia Oku, but the pattern elements often appear as fine metallic streaks across the forewing in these other genera, and it is difficult to separate the latter two genera from each other based on appearance. The absence of scaled ventral pockets near the base of the abdomen also separates Hiroshiinoueana from most species of Gatesclarkeana and Ukamenia. Hiroshiinoueana is characterized by the following genitalia characters: large dorso-basal spiny process or lobe of the valva and bristle cluster on the sacculus in the male genitalia; and the large, sclerotized, tubular sterigma and depressed signum with stellate teeth in the female genitalia. The genitalia of Gatesclarkeana are very similar to those of Hiroshiinoueana, but they can be distinguished by the right valva bearing a cluster of long bristles in the male genitalia, which is absent on left valva; and by the densely aciculate sterigma and the scobinate and concave signum (or signa) with a few teeth medially in the female genitalia. In Hiroshiinoueana there is one long bristle cluster on each valva in the male genitalia, and the sterigma is naked and the signum is a scobinate, rounded patch confluent with a stellate sclerite in the female genitalia. According to Horak (2006), the dorso-basal spiny process on the valva is derived from the sacculus. However, in the present study we found that this spiny process (or lobe) in H. inequivalva is derived from the distal part of the sacculus. whereas in H. wuzhishanica it appears to be derived from the base of cucullus, and is more like the expansion of a pulvinus from the cucullus. The M-stem in the forewing and the basal excavation in the male genitalia are present in the two new species, but neither character was illustrated or referred to in the original description of the two previously described species of the genus. The M-stem terminates between M2 and M3. In H. wuzhishanica there is a cluster of long black scales on inner side of the hind tibia in the male; this modification was not mentioned in the descriptions of the two previously known species, and is also absent in H. inequivalva. Razowski (1989) referred Hiroshiinoueana to Gatesclarkeanina and hypothesized that the structure of the valva, especially the distal portion (the neck and the cucullus), was its autapomorphy. Based on characters of the male genitalia (spiny process of valva), the female genitalia (shape of signa and sterigma), and forewing markings (conspicuous metallic spots), Horak (2006) considered Hiroshiinoueana to be closely related to Gatesclarkeana Diakonoff, Asymmetrarcha Diakonoff, and Ukamenia Oku., Published as part of Fei, Yao, Zhao, Jingxia, Liu, Kaili & Yu, Haili, 2018, First record of Hiroshiinoueana Kawabe, 1978 from China (Lepidoptera: Tortricidae: Olethreutinae), with descriptions of two new species, pp. 324-330 in Zootaxa 4429 (2) on pages 324-325, DOI: 10.11646/zootaxa.4429.2.7, http://zenodo.org/record/1284031, {"references":["Kawabe, A. (1978) Descriptions of three new genera and fourteen new species of the subfamily Olethreutinae from Japan (Lepidoptera, Tortricidae). Tinea, 10, 173 - 189.","Horak, M. (2006) Monograph on Australia Lepidoptera, Volume 10: Olethreutine Moths of Australia (Lepidoptera: Tortricidae). CSIRO Publishing, Collingwood, Victoria, 528 pp.","Razowski, J. (1989) The genera of Tortricidae (Lepidoptera) Part II: Palaearctic Olethreutinae. Acta Zoologica Cracoviensia, 32 (7), 107 - 328."]}

Fei, Yao, Zhao, Jingxia, Liu, Kaili, Yu, Haili (2018): First record of Hiroshiinoueana Kawabe, 1978 from China (Lepidoptera: Tortricidae: Olethreutinae), with descriptions of two new species. Zootaxa 4429 (2): 324-330, DOI: https://doi.org/10.11646/zootaxa.4429.2.7

Hiroshiinoueana wuzhishanica Fei & Yu, sp. nov. (Figs. 1, 2, 4) Type. Holotype: &male;, China, Hainan Province, Mt. Wuzhi, 18°86' N, 109°67' E, 700 m, 10 Apr 2013, leg. Yinghui Sun, Wei Guan & Tengteng, Liu, genitalia slide no. LKL13264. Diagnosis. This new species is similar to H. gangweonensis in male genitalia. It can be separated from the latter species by the straight gnathos, the folded valva with the sacculus longer than the cucullus and extending to the median part of the cucullus, and the length of bristle cluster of the sacculus, which is about equal to or longer than the cucullus. In H. gangweonensis the gnathos is curved, the valva is not folded lengthwise, the sacculus is not expanded and is shorter than the cucullus, and the bristle cluster is shorter than the cucullus but longer than the sacculus. Hiroshiinoueana wuzhishanica can be easily distinguished from H. inequivalva and H. stellifera by the relatively narrow tegumen and the identical bristle clusters on the left and right sacculus in the male genitalia. In addition, the cucullus is somewhat crescent-shaped in this new species, whereas the cucullus is broad and rounded in H. inequivalva and triangular in H. stellifera Kawabe; the dorso-basal spiny lobe of the valva is rounded in H. wuzhishanica, whereas it is narrow and elongate in H. inequivalva. Description. Adult (Fig. 1). Head: Vertex rough scaled, brown suffused with pale brown. Antenna brown, with scattered dark brown scales. Labial palpus porrect, brown mixed with pale brown; median segment expanded ventrally. Thorax: Pale brown suffused with yellowish brown, with scattered metallic-blue spots; posterior crest inconspicuous. Hind tibia in male not enlarged, bearing long black scales on inner surface of basal half (Fig. 2). Forewing length 6.5 mm; elongate and triangular, costa slightly arched, apex blunt; upperside ground color dark brown, with metallic blue spots throughout, pattern elements dark brown and inconspicuous; most costal strigulae inconspicuous, covered by metallic spots, striae from strigulae 3–7 indistinct, extending toward to dorsum and tornus; fringe dark brown; underside pale brown, area of overlap with hindwing paler. Hindwing upperside pale grayish brown, costa white, anal roll present and with long white scales inside; fringe pale grey; underside pale tawny. Abdomen: Male genitalia (Fig. 4) weakly sclerotized. Tegumen broad, rounded posteriorly. Uncus small, somewhat semicircular, hairy distally. Socius laterally plate-like, densely spined. Gnathos simple, represented by two straight, narrow, lateral bands. Valvae symmetrical; basal excavation distinct; each valva folded longitudinally, sacculus covered partly by cucullus and a large densely spiny lobe protruding inward from base of cucullus, somewhat rectangular and rounded, distinctly broader and slightly shorter than cucullus, with ventral edge adjacent to cucullus concave and aciculate, spines on lobe short and strong, pointing towards phallus; cucullus narrow, somewhat crescent-shaped, spiny; sacculus broad and long, apical part reaching about mid-length of cucullus, bearing a cluster of long bristles outside of mid-length of ventral edge, which is equal in length to sacculus and longer than cucullus. Anellus well sclerotized, large, broadly surrounding phallus; phallus simple, moderate, narrowed to distal end, pointed apically, without cornuti. Vinculum simple, slightly broadened. Female unknown. Molecular characterization. Partial mitochondrial gene COI sequence with GenBank accession number MG983839. The DNA barcode sequences for this and the species described below are the first barcode data for the genus Hiroshiinoueana submitted to GenBank. Etymology. The specific name is from the type locality, Mt. Wuzhi, Hainan Province.

Hiroshiinoueana inequivalva Fei & Yu, sp. nov. (Figs. 3, 5���8) Types. Holotype: &male;, China, Shaanxi Province, Langao, 32��22' N, 108��81' E, 877 m, 15 Aug 2016, leg. Weixing Feng & Wentao Shi, genitalia slide no. ZJX16346. Paratypes: 1 &male;, CHINA: Shaanxi Province: Langao, 32��23' N, 108��42' E, 1127 m, 29 Jul 2016, leg. Jingxia Zhao & Peng Liu; 1 &female;, Langao, 32��29' N, 108��87' E, 577 m, 18 Aug 2016, leg. Jingxia Zhao & Peng Liu; 1 &male;, Pingli, 32��03' N, 109��33' E, 772 m, 2 Aug 2016, leg. Jingxia Zhao & Peng Liu. Diagnosis. Hiroshiinoueana inequivalva differs from the two previously described species by the narrow and elongate dorso-basal spiny lobe of valva in the male genitalia, which is broad and rounded in the other two species. The new species also can be separated easily from H. gangweonensis by the bristle clusters of the valvae of different size and the cucullus with a rounded dorsal margin; in H. gangweonensis the bristle clusters of the valvae are identical on the right and left sides, and the cucullus is half-moon shaped and its dorsal margin is almost straight. Two additional characters of the male genitalia can be used to distinguish this new species from H. stellifera: the median portion of the gnathos is bilobed in H. inequivalva, whereas the gnathos is a transverse band with a pending process in H. stellifera; and the cucullus is rounded in this new species, whereas it is triangular in H. stellifera. Differences between this new species and H. wuzhishanica are provided above. Description. Adult (Fig. 3). Head: Vertex rough scaled, pale brown. Antenna pale brown, dusted with black scales. Labial palpus porrect, pale yellowish brown; median segment expanded ventrally, terminal segment pointed. Thorax: Yellowish brown with pale metallic spots. Hind tibia in male not enlarged. Forewing length 7.0��� 7.5 mm; long triangular, costa slightly arched apically, apex blunt; costa with distal 1/4 white; costal strigulae dingy white to pale brown; upperside ground color pale brown with light-blue metallic spots throughout, markings dark brown suffused with pale ochreous, with edges ill-defined; basal and subbasal fascia occupying basal 1/4 of wing; median fascia broad and oblique, proximal edge extending from 2/5 length of costa to mid-dorsum, distal edge reaching tornus; postmedian fascia connected with preterminal and terminal fascia, somewhat crescent shaped, lower part reaching termen between M2 and CuA1; termen white between apex and M2; white scales scattered over area between median fascia and postmedian fascia, forming several small pale dots inside tornus, indistinct in some specimens; fringe dark brown; underside pale brown. Hindwing pale brown except costa white, fringe pale brown, anal fold absent; underside pale brown. Abdomen: Male genitalia (Fig. 5) with tegumen strongly sclerotized. Uncus and socius weakly sclerotized; uncus reduced; socius drooping, finger-like, with basal part broad, sparsely spined. Gnathos strongly sclerotized, with lateral part very narrow, median portion protruding to two large rounded petal-shaped lobes, naked. Valvae with basal parts strongly sclerotized and distal parts weakly sclerotized; asymmetrical, left valva larger; basal excavation distinct; cucullus with basal part expanding inward to a large rounded lobe bearing rows of spines, most spines directed towards phallus, diminishing in size backward; sacculi asymmetrical; left sacculus larger, with basal part expanded and densely spined, apical part forming a rounded prominence and bearing a thick cluster of long bristles, length of bristles about equal to sacculus; right sacculus smaller, basal part same as left sacculus, distal part small and not expanded, apical bristle cluster adjacent to spined basal part, slender, length about 3/5 times that of left sheaf; cucullus weakly sclerotized, broad, folded longitudinally, with sparse spines, rounded distally. Anellus well sclerotized, broadly surrounding phallus; phallus simple, narrow, without cornuti. Vinculum simple, narrow. Female genitalia (Fig. 6) with papillae anales elongate. Anterior and posterior apophyses slender, about equal in length. Sterigma (Fig. 7) strongly sclerotized, smooth, deeply invaginated to form a thick tube and expanded medially. Ductus bursae with posterior 1/3 surrounded by sterigma, posterior half sclerotized, and anterior portion membranous; slender, except expanded at middle. Corpus bursae ovoid, granulated; signum (Fig. 8) a large, rounded, scobinate patch with seven elongate teeth radiating from a small central circle and pointing outward. Molecular characterization. Partial mitochondrial COI gene sequence with GenBank accession number MG983837 for one female paratype, MG983838 for one male paratype. Etymology. The specific name is derived from the Latin prefix in -, equi - (= equal) and valva, referring to the asymmetrical valvae in the male genitalia., Published as part of Fei, Yao, Zhao, Jingxia, Liu, Kaili & Yu, Haili, 2018, First record of Hiroshiinoueana Kawabe, 1978 from China (Lepidoptera: Tortricidae: Olethreutinae), with descriptions of two new species, pp. 324-330 in Zootaxa 4429 (2) on pages 327-330, DOI: 10.11646/zootaxa.4429.2.7, http://zenodo.org/record/1284031

Hiroshiinoueana inequivalva Fei & Yu, sp. nov. (Figs. 3, 5–8) Types. Holotype: &male;, China, Shaanxi Province, Langao, 32°22' N, 108°81' E, 877 m, 15 Aug 2016, leg. Weixing Feng & Wentao Shi, genitalia slide no. ZJX16346. Paratypes: 1 &male;, CHINA: Shaanxi Province: Langao, 32°23' N, 108°42' E, 1127 m, 29 Jul 2016, leg. Jingxia Zhao & Peng Liu; 1 &female;, Langao, 32°29' N, 108°87' E, 577 m, 18 Aug 2016, leg. Jingxia Zhao & Peng Liu; 1 &male;, Pingli, 32°03' N, 109°33' E, 772 m, 2 Aug 2016, leg. Jingxia Zhao & Peng Liu. Diagnosis. Hiroshiinoueana inequivalva differs from the two previously described species by the narrow and elongate dorso-basal spiny lobe of valva in the male genitalia, which is broad and rounded in the other two species. The new species also can be separated easily from H. gangweonensis by the bristle clusters of the valvae of different size and the cucullus with a rounded dorsal margin; in H. gangweonensis the bristle clusters of the valvae are identical on the right and left sides, and the cucullus is half-moon shaped and its dorsal margin is almost straight. Two additional characters of the male genitalia can be used to distinguish this new species from H. stellifera: the median portion of the gnathos is bilobed in H. inequivalva, whereas the gnathos is a transverse band with a pending process in H. stellifera; and the cucullus is rounded in this new species, whereas it is triangular in H. stellifera. Differences between this new species and H. wuzhishanica are provided above. Description. Adult (Fig. 3). Head: Vertex rough scaled, pale brown. Antenna pale brown, dusted with black scales. Labial palpus porrect, pale yellowish brown; median segment expanded ventrally, terminal segment pointed. Thorax: Yellowish brown with pale metallic spots. Hind tibia in male not enlarged. Forewing length 7.0– 7.5 mm; long triangular, costa slightly arched apically, apex blunt; costa with distal 1/4 white; costal strigulae dingy white to pale brown; upperside ground color pale brown with light-blue metallic spots throughout, markings dark brown suffused with pale ochreous, with edges ill-defined; basal and subbasal fascia occupying basal 1/4 of wing; median fascia broad and oblique, proximal edge extending from 2/5 length of costa to mid-dorsum, distal edge reaching tornus; postmedian fascia connected with preterminal and terminal fascia, somewhat crescent shaped, lower part reaching termen between M2 and CuA1; termen white between apex and M2; white scales scattered over area between median fascia and postmedian fascia, forming several small pale dots inside tornus, indistinct in some specimens; fringe dark brown; underside pale brown. Hindwing pale brown except costa white, fringe pale brown, anal fold absent; underside pale brown. Abdomen: Male genitalia (Fig. 5) with tegumen strongly sclerotized. Uncus and socius weakly sclerotized; uncus reduced; socius drooping, finger-like, with basal part broad, sparsely spined. Gnathos strongly sclerotized, with lateral part very narrow, median portion protruding to two large rounded petal-shaped lobes, naked. Valvae with basal parts strongly sclerotized and distal parts weakly sclerotized; asymmetrical, left valva larger; basal excavation distinct; cucullus with basal part expanding inward to a large rounded lobe bearing rows of spines, most spines directed towards phallus, diminishing in size backward; sacculi asymmetrical; left sacculus larger, with basal part expanded and densely spined, apical part forming a rounded prominence and bearing a thick cluster of long bristles, length of bristles about equal to sacculus; right sacculus smaller, basal part same as left sacculus, distal part small and not expanded, apical bristle cluster adjacent to spined basal part, slender, length about 3/5 times that of left sheaf; cucullus weakly sclerotized, broad, folded longitudinally, with sparse spines, rounded distally. Anellus well sclerotized, broadly surrounding phallus; phallus simple, narrow, without cornuti. Vinculum simple, narrow. Female genitalia (Fig. 6) with papillae anales elongate. Anterior and posterior apophyses slender, about equal in length. Sterigma (Fig. 7) strongly sclerotized, smooth, deeply invaginated to form a thick tube and expanded medially. Ductus bursae with posterior 1/3 surrounded by sterigma, posterior half sclerotized, and anterior portion membranous; slender, except expanded at middle. Corpus bursae ovoid, granulated; signum (Fig. 8) a large, rounded, scobinate patch with seven elongate teeth radiating from a small central circle and pointing outward. Molecular characterization. Partial mitochondrial COI gene sequence with GenBank accession number MG983837 for one female paratype, MG983838 for one male paratype. Etymology. The specific name is derived from the Latin prefix in -, equi - (= equal) and valva, referring to the asymmetrical valvae in the male genitalia.

Colorectal cancer (CRC) accounts for over 600 000 deaths annually worldwide. The current study aims to evaluate the value of proto‐oncogene PIM1 as a therapeutic target in CRC and investigate the anticancer activity of hispidulin, a naturally occurring phenolic flavonoid compound, against CRC. Immunohistochemistry analysis showed that PIM1 was upregulated in CRC tissue. The role of PIM1 as an oncogene was evidenced by the fact that PIM1 knockdown inhibits cell growth, induces apoptosis, and suppresses invasion. Our results showed that hispidulin exerts antitumor activity in CRC through inhibiting the expression of PIM1. Moreover, our findings revealed that hispidulin downregulated the expression of PIM1 by inhibiting JAK2/STAT3 signaling by generating reactive oxygen species. Furthermore, our in vivo studies showed that hispidulin can significantly inhibit tumor growth and metastasis in CRC. Collectively, our results provide an experimental basis for trialing hispidulin in CRC treatment. PIM1 can be considered a potential therapeutic target in CRC.

Context adaptive binary arithmetic coding (CABAC) is the entropy coding tool applied in the latest video coding standard, High Efficiency Video Coding (H.265/HEVC). CABAC achieves high coding efficiency but involves the bin-to-bin data dependency of Binary Arithmetic Encoder (BAE). This paper proposes a range updating structure with pre-bitwise-NOT (PBN) operation to shorten the critical paths in the range updating stage of the BAE, and also proposes a BAE architecture with optimized Lookahead rLPS. Synthesized results in SMIC 40nm show that the proposed architecture can operate at 436.7MHz and the throughput is 1777Mbin/s.