1. Skin grafting prevents recurrence in Dupuytren's disease and extension correlates with fibrosis diathesis score
- Author
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I. Couck, Marieke Torrekens, Ilse Degreef, M. Van Nuffel, and L. De Smet
- Subjects
medicine.medical_specialty ,medicine.medical_treatment ,Disease ,030230 surgery ,Cohort Studies ,03 medical and health sciences ,0302 clinical medicine ,Disease severity ,Fibrosis ,Humans ,Medicine ,Orthopedics and Sports Medicine ,Family history ,Dupuytren's contracture ,030222 orthopedics ,integumentary system ,business.industry ,Rehabilitation ,Skin Transplantation ,Diathesis ,medicine.disease ,Surgery ,Dupuytren Contracture ,Skin grafting ,Disease Susceptibility ,Neoplasm Recurrence, Local ,medicine.symptom ,business ,Cohort study - Abstract
Full thickness grafting can be considered after fasciectomy for Dupuytren contracture in severe cases with skin shortage or in radical dermofasciectomy. It is a common dogma that these skin grafts may prevent disease recurrence. We reviewed 47 patients after fasciectomy and full-thickness skin grafting for Dupuytren contracture at 3-16 years' follow-up. Recurrence beneath the skin graft and extension of the disease in the rest of the hand were recorded. Age at onset, gender and factors considered to influence the outcome due to fibrosis diathesis, such as bilateral disease, family history and ectopic lesions, were noted. The Tubiana classification was used to grade disease severity at surgery and at follow-up. None of the patients manifested recurrence underneath the skin graft, but the disease did show extension in 83% of cases. Disease extension was more likely in patients with higher fibrosis diathesis scores. We conclude that skin grafting may prevent disease recurrence underneath the grafts, but extension of the disease correlates with fibrosis diathesis. LEVEL OF EVIDENCE: IV, therapeutic cohort study.
- Published
- 2021