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KLOCEK, Konrad, KOSTECKI, Bartosz, HAJDUK, Aleksandra, MROZEK, Łukasz, JUREK, Aleksander, ZWOLSKI, Maciej, SZUMLAS, Zuzanna & PUCHALSKI, Krzysztof. Treatment of lumbar intervertebral disc herniation - a review of the latest therapeutic methods.Journal of Education, Health and Sport. 2023;25(1):16-26. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2023.25.01.002 https://apcz.umk.pl/JEHS/article/view/43551 https://zenodo.org/record/7884396 The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 21, 2021. No. 32343. Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences). Punkty Ministerialne z 2019 - aktualny rok 40 punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 21 grudnia 2021 r. Lp. 32343. Posiada Unikatowy Identyfikator Czasopisma: 201159. Przypisane dyscypliny naukowe: Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu); Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu). © The Authors 2023; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 12.04.2023. Revised: 12.04.2023. Accepted: 01.05.2023. Published: 01.05.2023. Treatment of lumbar intervertebral disc herniation - a review of the latest therapeutic methods. Konrad Klocek 1, Bartosz Kostecki 2, Aleksandra Hajduk 3, Łukasz Mrozek 4, Aleksander Jurek 5, Maciej Zwolski 6, Zuzanna Szumlas 7, Krzysztof Puchalski 8 1 Górnośląskie Centrum Medyczne im. prof. Leszka Gieca Śląskiego Uniwersytetu Medycznego w Katowicach, Ziołowa 45-47, 40-635 Katowice 2 SP ZOZ Szpital Wielospecjalistyczny w Jaworznie, Józefa Chełmońskiego 28, 43-600 Jaworzno 3 Warszawski Uniwersytet Medyczny, Żwirki i Wigury 61, 02-091 Warszawa 4 Samodzielny Publiczny Specjalistyczny Szpital Zachodni im. Św. Jana Pawła II, ul. Daleka 11, 05-825 Grodzisk Mazowiecki, Poland 5UCK WUM Szpital Kliniczny Dzieciątka Jezus, ul. Lindleya 4, 02-005 Warszawa 6 Szpital św. Elżbieta w Katowicach ul. Warszawska 52, 40-008 Katowice 7 LUX MED Sp. z o.o., ul. Postępu 21C, 02-676 Warszawa 8 Samodzielny Publiczny Zespół Zakładów Opieki Zdrowotnej im. Marszałka Józefa Piłsudskiego w Płońsku, 09-100 Płońsk, ul. Henryka Sienkiewicza 7 Abstract Introduction and purpose:The aim of this study is to provide a comprehensive description of intervertebral disc herniation, with a focus on the lumbar spine, including the current conservative and modern surgical treatment options such as minimally invasive procedures. State of Knowledge: Spinal pain is a prevalent cause of disability in developed countries, with an increasing number of people affected by this condition. Intervertebral disc herniation resulting from degenerative changes is a common pathology, particularly in the lumbar and cervical spine. This condition involves the protrusion of the nucleus pulposus, which exerts pressure on the spinal roots, causing irritation. While the prognosis for herniated nucleus pulposus is usually positive and many patients can undergo conservative treatment, some may require a surgery. Due to advancements in technology, the current goal is to minimize tissue trauma during hernia repair procedures. Conclusions:Due to advances in treatment of lumbar intervertebral disc herniation, patients can achieve better clinical outcomes and improved quality of life. Conservative treatment should be considered as the first line treatment in a majority of cases. Surgery is usually a last resort when conservative treatment proves insufficient. No surgical method seems to be unequivocally superior to the others, so its choice is tailored to the individual patient's needs and depends on the surgeon's preferences and experience. Recent advances in endoscopic spine surgery are providing new insights into disc surgery and pain management strategies. Key words:intervertebral disc herniation; spondylodesis; discectomy; sciatica

HAJDUK, Aleksandra, MROZEK, Łukasz, KLOCEK, Konrad, KOSTECKI, Bartosz, JUREK, Aleksander, ZWOLSKI, Maciej, SZUMLAS, Zuzanna & PUCHALSKI, Krzysztof. When Common Medications Trigger a Rare Reaction: A Review of Clinical Features, Diagnosis, and Treatment Options of DRESS Syndrome.Journal of Education, Health and Sport. 2023;29(1):11-21. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2023.29.01.001 https://apcz.umk.pl/JEHS/article/view/43623 https://zenodo.org/record/7927094 The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to the announcement of the Minister of Education and Science of December 21, 2021. No. 32343. Has a Journal's Unique Identifier: 201159. Scientific disciplines assigned: Physical Culture Sciences (Field of Medical sciences and health sciences); Health Sciences (Field of Medical Sciences and Health Sciences). Punkty Ministerialne z 2019 - aktualny rok 40 punktów. Załącznik do komunikatu Ministra Edukacji i Nauki z dnia 21 grudnia 2021 r. Lp. 32343. Posiada Unikatowy Identyfikator Czasopisma: 201159. Przypisane dyscypliny naukowe: Nauki o kulturze fizycznej (Dziedzina nauk medycznych i nauk o zdrowiu); Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu). © The Authors 2023; This article is published with open access at Licensee Open Journal Systems of Nicolaus Copernicus University in Torun, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author (s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non commercial license Share alike. (http://creativecommons.org/licenses/by-nc-sa/4.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 18.04.2023. Revised: 20.04.2023. Accepted: 15.05.2023. Published: 15.05.2023. When Common Medications Trigger a Rare Reaction: A Review of Clinical Features, Diagnosis, and Treatment Options of DRESS Syndrome Aleksandra Hajduk 1, Łukasz Mrozek 2,Konrad Klocek 3, Bartosz Kostecki 4, Aleksander Jurek 5, MaciejZwolski 6, Zuzanna Szumlas 7, Krzysztof Puchalski 8 1 Warszawski Uniwersytet Medyczny, Żwirki i Wigury 61, 02-091 Warszawa, Poland https://orcid.org/0009-0005-4648-376X 2 Samodzielny Publiczny Specjalistyczny Szpital Zachodni im. Św. Jana Pawła II, ul. Daleka 11, 05-825 Grodzisk Mazowiecki, Poland https://orcid.org/0009-0009-3262-8576 3 Górnośląskie Centrum Medyczne im. prof. Leszka Gieca Śląskiego Uniwersytetu Medycznego w Katowicach, Ziołowa 45-47, 40-635 Katowice, Poland https://orcid.org/0000-0002-3628-4223 4 SP ZOZ Szpital Wielospecjalistyczny w Jaworznie, Józefa Chełmońskiego 28, 43-600 Jaworzno, Poland https://orcid.org/0009-0002-6305-1764 5UCK WUM Szpital Kliniczny Dzieciątka Jezus, ul. Lindleya 4, 02-005 Warszawa, Poland https://orcid.org/0009-0000-4858-5595 6 Szpital św. Elżbieta w Katowicach ul. Warszawska 52, 40-008 Katowice, Poland https://orcid.org/0000-0001-7255-4668 7 LUX MED Sp. z o.o., ul. Postępu 21C, 02-676 Warszawa, Poland https://orcid.org/0009-0007-4154-2796 8 Samodzielny Publiczny Zespół Zakładów Opieki Zdrowotnej im. Marszałka Józefa Piłsudskiego w Płońsku, 09-100 Płońsk, ul. Henryka Sienkiewicza 7, Poland https://orcid.org/0009-0005-2366-4971 ABSTRACT Introduction and purpose: Drug-induced reaction with eosinophilia and systemic symptoms (DRESS) is a severe, life-threatening systemic drug reaction. The challenges in identifying DRESS syndrome result from its symptoms being variable, diverse, and unspecific. Due to the potentially lethal consequence, any clinician should be aware of the symptomatology and be prepared to initiate the appropriate steps. This review summarizes the clinical manifestations and provides essential information on the management of the illness. State of knowledge:DRESS appears to be a rare reaction that frequently remains undetected due to its atypical clinical presentation. Fever, skin rash, lymphadenopathy, eosinophilia, and organ involvement as well as other manifestations, may occur. The onset may be delayed by weeks after exposure to the offending drug. DRESS syndrome is classified as a type IV hypersensitivity. It is thought to be triggered by antiepileptic drugs and antibiotics although many other medications can cause the condition. Certain genetic factors may also predispose some individuals to develop DRESS. Combining clinical and laboratory findings can help confirm the diagnosis. Discontinuation of the offending drug is the fundamental component of treatment such as supportive care including the use of antihistamines and corticosteroids, but recent research has discovered additional promising therapy options. Conclusions: Detecting DRESS syndrome early is crucial to ensure prompt treatment, prevent serious complications, and improve patient outcomes. Healthcare providers should be aware of the signs and symptoms of DRESS syndrome, especially in patients taking particular medications, and be prepared to investigate further if it is suspected. Keywords DRESS, drug reaction, eosinophilia, cutaneous reaction, hypersensitivity

Background: Recent studies have changed the perception of rhythm control in the treatment of atrial fibrillation (AF). Functional mitral regurgitation (fMR) can be both a cause and a consequence of AF and may influence rhythm restoration procedures. Materials and methods: A retrospective analysis included 182 consecutive patients with AF on optimal medical therapy (OMT) undergoing electrical cardioversion (CVE). Based on transthoracic echocardiography, the study group was divided into 20 (11%) patients without mitral regurgitation (MR) and 132 (82%) with fMR 77 (58%) with atrial fMR (afMR; left ventricle ejection fraction (LVEF) ≥ 50%, left atrial (LA) dilatation) and 55 (42%) and with ventricular fMR (vfMR; LVEF < 50%). Patients with severe and organic MR were excluded from the study. Results: vfMR patients had a greater incidence of kidney failure (p = 0.01) and coronary heart disease (p = 0.02); more frequent use of diuretics during hospitalization (p < 0.01); greater LA diameter and area (p < 0.01; p < 0.01) than afMR patients. CVE efficiency was high in all four groups (84–95%). The presence and type of fMR did not affect the efficacy of CVE (p = 0.2; p = 0.9) and did not require the use of more energy (p = 0.4; p = 0.8). The independent predictor of successful CVE was the amount of white blood cells (OR 0.74, p < 0.05). Conclusions: Efficacy of CVE is high among AF patients on OMT regardless of the incidence and type of fMR. Subclinical inflammation should be excluded before elective CVE because it may decrease its efficacy.

We sought to compare the safety and efficiency of Tiger-2 in the right radial and Judkins catheter in the left radial access. We retrospectively collected data of 487 patients, involving 172 patients after coronary angiography with Judkins on the left radial artery and 315 patients with Tiger-2 on the right radial artery access. There were no differences in baseline characteristics, except for hypertension ratio and mean age. There was a difference in pulse absence on the radial artery. The volume of contrast used was higher in the Judkins group. Both groups differed in the amount of drugs administered (NTG and heparin). Fluorescence times were comparable between groups. Radiation dosage and AK was significantly greater in the Tiger-2 group. The Tiger-2 catheters were significantly more often changed to another type of catheter (100 changes) than the Judkins (12 changes). However, there was no statistical difference in access site change. Judkins with left radial access seems to be a safer option because of the lower radiation exposure and less incidence of complications than Tiger-2 with right radial access, however, it requires a higher volume of contrast.