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Aim of the study: To determine the efficacy of Hyaluronic acid gel in management of postoperative complications after impacted mandibular third molar surgery. Materials and Method: This prospective, single-centeredstudy follow a split mouth-design, where the patients were act as their own control. A total of 40 patients were included in study.The study subjects were assigned into two groups: Control Group and Study Group (0.8 % Hyaluronic acid gel). Once selected, each patient will be assigned a serial number. According to their respective serial numbers, patients with odd serial number will be administered 2ml 0.8% hyaluronic acid gel (Gengigel ) in the postextraction socket of impacted mandibular third molar of the left side, and the right side will act as control, an interval of 4 weeksis kept between the 2 surgeries. In even numbered patients, the right side extraction socket will be administered 2 ml 0.8 % hyaluronic acid gel (Gengigel)and the left side acted as the control. . Post-operative pain, trismus, swelling & soft tissue healing were evaluated on 1st, 3rd and 7th postoperative days . Results:0.8 % Hyaluronic acid gelhas shown a beneficial results in the reduction of postoperative pain on 7thday and soft tissue healing on 3rdand 7thdays , the results were statistically significant, although the results for trismus and swellingwas not statistically significant. Conclusion :The efficacy of Hyaluronic acid gel has proven to be an important therapeutic adjuvant for reducing postoperative pain & improve soft tissue healingfollowing mandibular third molar surgery and thus improving patients quality of life. &nbsp

Rapid growth of population and resulting urbanization is gaining momentum where urban areas are developed in significant proportion in India leading to changes in existing landscape, buildings, roads, and other supporting infrastructure. Such a change replaces open land and vegetation in the form of permeable surfaces with concrete surfaces which are impermeable and dry in nature which leads to the formation of urban heat islands whereby urban regions experience warmer temperatures than their adjacent rural surroundings. Such heat island effect increases energy consumption in urban areas along with other negative impacts. The authors of the present paper focus on reduction of heat island effect in urban areas along with compatible strategies in Indian conditions partly to address higher energy consumptions and partly to reduce other negative impacts being caused on account of such heat island effects. The authors have carried out a case study of Jaipur a pink city of India.

School of Studies in Chemistry & Biochemistry, Vikram University, Ujjain-456 010, Madhya Pradesh. India E-mail: neelkamalchem@gmail.com Prashanti College of Engineering, Ujjain, Madhya Pradesh. India E-mail: inf_vw@rediffmail.com Manuscript received 12 October 2010, accepted 27 October 2010 The paper describe modeling of log IC50 representing in vivo antitumor activity using chemical as well as topological descriptors. The results hove shown that the chemical descriptors ore no useful for modeling of the antitumor activity. However, topological indices In multiparametric regression yielded excellent models. The \(HO-NH_\rangle-\sqsubset\sqsupset[CH_2]-\)N R1 R2 results are discussed using a variety of statistical parameters. &nbsp