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Introduction: There is a widespread prevalence of obesity and growing evidence suggests its possible adverse effect on cognitive functions. Hence, it is important to study the relationship between Body Mass Index (BMI) and Cognitive Functions. Aim: The aim of this study was to find out the association between BMI and cognitive functions in medical students. The present study also determined whether there are any gender based difference of association of BMI and cognitive functions. Materials and Methods: A cross-sectional study was done at Cognitive function test Laboratory of Dr. Vasantrao Pawar Medical College, Hospital and Research Centre, Nashik between July and December 2016. Study was done on randomly selected medical undergraduate students (50 male and 50 females) of 18-25 years age group. Height and weight were recorded and subjects were divided into 3 groups based on BMI (in kg/m2) as: Underweight (BMI 25 kg/m2). In all the above BMI groups, four domains of cognitive functions were assessed i.e., attention, perception, executive functions and working memory using Visual and Auditory Reaction Time (VRT and ART) and Go/No-Go VRT and ART; Fast Counting (FC); Eriksen Flanker Test (EFT) and Stroop Test (ST) and Visual Forward (VFDS) and Backward Digit Span (VBDS) test, respectively. The data was statistically analysed and different cognitive function tests were compared in various categories of BMI (viz., underweight, normal and overweight) using ANOVA and Tukey HSD tests. Gender based association of BMI and cognitive functions were also assessed. The data was analysed statistically using SPSS version 16.0 and p-value