171 results on '"Jian Qiang Li"'
Search Results
2. Heterogeneous graph embedding model for predicting interactions between TF and target gene
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Yu-An Huang, Gui-Qing Pan, Jia Wang, Jian-Qiang Li, Jie Chen, and Yang-Han Wu
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Statistics and Probability ,Computational Mathematics ,Binding Sites ,Computational Theory and Mathematics ,Humans ,Molecular Biology ,Biochemistry ,Software ,Transcription Factors ,Computer Science Applications - Abstract
Motivation Identifying the target genes of transcription factors (TFs) is of great significance for biomedical researches. However, using biological experiments to identify TF–target gene interactions is still time consuming, expensive and limited to small scale. Existing computational methods for predicting underlying genes for TF to target is mainly proposed for their binding sites rather than the direct interaction. To bridge this gap, we in this work proposed a deep learning prediction model, named HGETGI, to identify the new TF–target gene interaction. Specifically, the proposed HGETGI model learns the patterns of the known interaction between TF and target gene complemented with their involvement in different human disease mechanisms. It performs prediction based on random walk for meta-path sampling and node embedding in a skip-gram manner. Results We evaluated the prediction performance of the proposed method on a real dataset and the experimental results show that it can achieve the average area under the curve of 0.8519 ± 0.0731 in fivefold cross validation. Besides, we conducted case studies on the prediction of two important kinds of TF, NFKB1 and TP53. As a result, 33 and 32 in the top-40 ranking lists of NFKB1 and TP53 were successfully confirmed by looking up another public database (hTftarget). It is envisioned that the proposed HGETGI method is feasible and effective for predicting TF–target gene interactions on a large scale. Availability and implementation The source code and dataset are available at https://github.com/PGTSING/HGETGI. Supplementary information Supplementary data are available at Bioinformatics online.
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- 2022
3. A Fundus Image Myopia Diagnosis Model Based on Homogeneous Multimodal Feature Fusion
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Peng- Ceng Wen, Yu Guan, Jian- Qiang Li, Tariq Mahmood, and Yin-Zheng Zhao
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- 2023
4. Capsulated Graph Neural Network for Ubiquitylation Sites Prediction
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Jie Chen, Ting-Bo Chen, Chen-Qiu Zhang, Ling-Yan Gu, Jia Wang, Yao-Xing Wu, and Jian-Qiang Li
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- 2022
5. Simulation Palynologists for Pollinosis Prevention: A Progressive Learning of Pollen Localization and Classification for Whole Slide Images
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Lin-Na Zhao, Jian-Qiang Li, Wen-Xiu Cheng, Su-Qin Liu, Zheng-Kai Gao, Xi Xu, Cai-Hua Ye, and Huan-Ling You
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General Immunology and Microbiology ,pollinosis prevention ,whole slide images ,progressive learning ,deep learning ,pollen localization and classification ,General Agricultural and Biological Sciences ,General Biochemistry, Genetics and Molecular Biology - Abstract
Existing API approaches usually independently leverage detection or classification models to distinguish allergic pollens from Whole Slide Images (WSIs). However, palynologists tend to identify pollen grains in a progressive learning manner instead of the above one-stage straightforward way. They generally focus on two pivotal problems during pollen identification. (1) Localization: where are the pollen grains located? (2) Classification: which categories do these pollen grains belong to? To perfectly mimic the manual observation process of the palynologists, we propose a progressive method integrating pollen localization and classification to achieve allergic pollen identification from WSIs. Specifically, data preprocessing is first used to cut WSIs into specific patches and filter out blank background patches. Subsequently, we present the multi-scale detection model to locate coarse-grained pollen regions (targeting at “pollen localization problem”) and the multi-classifiers combination to determine the fine-grained category of allergic pollens (targeting at “pollen classification problem”). Extensive experimental results have demonstrated the feasibility and effectiveness of our proposed method.
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- 2022
6. [Research advances in the impacts of oil pollutants on birds and the cleaning and repairing techniques]
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Yu-Cheng, Xie, Zi-Qiang, Zhu, Ji-Liang, Xu, Wei-Pan, Lei, De, Chen, Dong-Lai, Li, Jian-Qiang, Li, and Zheng-Wang, Zhang
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Birds ,Animals ,Humans ,Environmental Pollutants ,Petroleum Pollution ,Ecosystem ,Water Pollutants, Chemical - Abstract
Oil and its pollutants, which enter environment through natural oil seepage and many human activities, have considerable impacts on birds. We summarized the research advances in how oil pollutants influence birds and the cleaning technology of polluted birds and their habitats. The toxicity and destruction to feather structure are the major impacts of oil pollution on birds. Oil pollution can lead to birds' death, and also produce many chronic harms, including causing hemolytic anemia, reducing their immunity, disrupting thermal insulation and waterproo-fing performance of feather. It is an important way to reduce the impacts of oil pollution on birds by timely cleaning up the oil in bird habitats as well as carrying out the clean and repair work to the polluted birds. As a big oil-consuming country, China has been left behind by foreign countries in the studies of the effects of oil pollution on birds. More attention should be paid on the short-term and long-term impacts of oil pollution on birds and the cleaning and remediation technologies of the polluted birds and their habitats.石油污染物通过自然泄漏和各种人类活动进入生态环境,对鸟类的生存产生影响。本文综述了国内外有关石油污染物对鸟类所产生的影响、受污染鸟类及其栖息地的清洁修复技术的研究现状以及发展趋势。现有研究发现,石油的毒性和石油对羽毛结构与功能的破坏是石油污染影响鸟类的主要原因。石油污染不仅对鸟类有直接的致死作用,而且能产生许多慢性危害,包括引起鸟类溶血性贫血、使其免疫能力下降、降低羽毛的保温和防水能力等。对鸟类栖息地中的石油污染进行及时清理并开展对受污染鸟类的清洁修复工作,是减轻石油污染对鸟类影响的重要手段。我国作为石油消费大国,关于石油污染对鸟类影响的研究与国外相比滞后,亟需在石油污染对鸟类的短期和长期影响、受污染鸟类及其栖息地的清洁修复技术等方面开展更多的研究。.
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- 2022
7. Programmed cell death protein-1 inhibitor combined with chimeric antigen receptor T cells in the treatment of relapsed refractory non-Hodgkin lymphoma: A case report
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Xuejun Zhang, Shu-Peng Wen, Ying Wang, Jian-Qiang Li, Li Sun, Lina Xing, Zhi-Yun Niu, Zheng-Rong Song, and Fuxu Wang
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Programmed cell death ,business.industry ,Programmed Cell Death Protein 1 Inhibitor ,General Medicine ,medicine.disease ,Chimeric antigen receptor ,Lymphoma ,03 medical and health sciences ,0302 clinical medicine ,Relapsed/refractory non-Hodgkin lymphoma ,Chimeric antigen receptor T cell ,immune system diseases ,hemic and lymphatic diseases ,030220 oncology & carcinogenesis ,Case report ,Relapsed refractory ,medicine ,Cancer research ,Programmed cell death protein 1 inhibitor ,Hodgkin lymphoma ,030211 gastroenterology & hepatology ,business - Abstract
BACKGROUND Chimeric antigen receptor T cell (CART) therapy has benefited many refractory lymphoma patients, but some patients experience poor effects. Previous studies have shown that programmed cell death protein-1 (PD-1) inhibitors can improve and prolong the therapeutic effect of CAR-T cell treatment. CASE SUMMARY A 61-year-old male presented with 15-d history of diarrhea and lower-limb edema. A large mass was detected in the pelvis, and pathology indicated non-Hodgkin diffuse large B-cell lymphoma. After three cycles of the R-CHOP chemotherapeutic regimen, the patient showed three subcutaneous nodules under the left armpit and both sides of the cervical spine. Pathological examination of the nodules indicated DLBCL again. The patient was diagnosed with relapsed and refractory diffuse large B-cell lymphoma. We recommended CAR-T cell treatment. Before treatment, the patient’s T cell function and expression of immune detection points were tested. Expression of PD-1 was obviously increased (52.7%) on cluster of differentiation (CD)3+ T cells. The PD-1 inhibitor (3 mg/kg) was infused prior to lymphodepleting chemotherapy with fludarabine and cyclophosphamide. CAR-CD19 T cells of 3 × 106/kg and CAR-CD22 T cells 1 × 106/kg were infused, respectively. The therapeutic effect was significant, and the deoxyribonucleic acid copy numbers of CAR-CD19 T cells and CAR-CD22 T cells were stable. Presently, the patient has been disease-free for more than 12 mo. CONCLUSION This case suggests that the combination of PD-1 inhibitors and CAR-T cells improved therapeutic efficacy in B-cell lymphoma.
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- 2021
8. Preparation of Ce3+∶Y3Al5O12-Al2O3 Nano Ceramics by Aerodynamic Suspension Solidification for LDs-driven Lighting Application
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Jian-qiang Li, Ying Zahng, Yong-chang Guo, and Shao-wei Feng
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Radiation ,Materials science ,Chemical engineering ,visual_art ,Nano ,visual_art.visual_art_medium ,Ceramic ,Condensed Matter Physics ,Suspension (vehicle) ,Electronic, Optical and Magnetic Materials - Published
- 2021
9. Profiles of Cytokinins Metabolic Genes and Endogenous Cytokinins Dynamics during Shoot Multiplication In Vitro of Phalaenopsis
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Yuan-Yuan Li, Zhi-Gang Hao, Shuo Miao, Xiong Zhang, Jian-Qiang Li, Shun-Xing Guo, and Yung-I Lee
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Inorganic Chemistry ,Phalaenopsis ,micropropagation ,cytokinins ,gene expression ,Organic Chemistry ,fungi ,food and beverages ,General Medicine ,Physical and Theoretical Chemistry ,Molecular Biology ,Spectroscopy ,Catalysis ,Computer Science Applications - Abstract
Shoot multiplication induced by exogenous cytokinins (CKs) has been commonly used in Phalaenopsis micropropagation for commercial production. Despite this, mechanisms of CKs action on shoot multiplication remain unclear in Phalaenopsis. In this study, we first identified key CKs metabolic genes, including six isopentenyltransferase (PaIPTs), six cytokinin riboside 5′ monophosphate phosphoribohydrolase (PaLOGs), and six cytokinin dehydrogenase (PaCKXs), from the Phalaenopsis genome. Then, we investigated expression profiles of these CKs metabolic genes and endogenous CKs dynamics in shoot proliferation by thidiazuron (TDZ) treatments (an artificial plant growth regulator with strong cytokinin-like activity). Our data showed that these CKs metabolic genes have organ-specific expression patterns. The shoot proliferation in vitro was effectively promoted with increased TDZ concentrations. Following TDZ treatments, the highly expressed CKs metabolic genes in micropropagated shoots were PaIPT1, PaLOG2, and PaCKX4. By 30 days of culture, TDZ treatments significantly induced CK-ribosides levels in micropropagated shoots, such as tZR and iPR (2000-fold and 200-fold, respectively) as compared to the controls, whereas cZR showed only a 10-fold increase. Overexpression of PaIPT1 and PaLOG2 by agroinfiltration assays resulted in increased CK-ribosides levels in tobacco leaves, while overexpression of PaCKX4 resulted in decreased CK-ribosides levels. These findings suggest de novo biosynthesis of CKs induced by TDZ, primarily in elevation of tZR and iPR levels. Our results provide a better understanding of CKs metabolism in Phalaenopsis micropropagation.
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- 2022
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10. The relationship between the diurnal activity rhythm of Reeves’s pheasant (Syrmaticus reevesii) and human disturbance revealed by camera trapping
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Junqin Hua, Jiangyan Shi, Jian-Qiang Li, Yu-Ze Zhao, Ji-Liang Xu, and Hai Yang
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Disturbance (geology) ,Ecology ,biology ,Behavioral plasticity ,biology.animal ,Activity rhythms ,Syrmaticus reevesii ,Zoology ,biology.organism_classification ,Pheasant ,Ecology, Evolution, Behavior and Systematics ,Nature and Landscape Conservation - Published
- 2020
11. Optimal management of coronary artery disease in cancer patients
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Zulfiia Khannanova, Yue Li, Jian-Qiang Li, and Xue-Jie Han
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Medicine (General) ,medicine.medical_specialty ,Cancer therapy ,Inflammation ,030204 cardiovascular system & hematology ,medicine.disease_cause ,Coronary artery disease ,03 medical and health sciences ,Review article ,R5-920 ,0302 clinical medicine ,Internal medicine ,medicine ,cardiovascular diseases ,Survival rate ,Cancer ,business.industry ,medicine.disease ,Optimal management ,Cardio-oncology ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,Cardiology ,medicine.symptom ,business ,Oxidative stress ,Artery - Abstract
Owing to early diagnosis and rapid development of treatments for cancers, the five-year survival rate of all cancer types has markedly improved worldwide. Over time, however, there has been an increase in the number of cancer patients who develop coronary artery disease (CAD) due to different causes. First, many risk factors are shared between cancer and CAD. Second, inflammation and oxidative stress are common underlying pathogeneses in both disorders. Lastly, cancer therapy can result in endothelial injury, coronary artery spasm, and coagulation, thereby increasing the risk of CAD. As more cancer patients are being diagnosed with CAD, specialized cardiac care should be established to minimize the cardiovascular mortality of cancer survivors. Keywords: Cancer, Coronary artery disease, Cardio-oncology
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- 2019
12. GraphTGI: an attention-based graph embedding model for predicting TF-target gene interactions
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Zhi-Hua Du, Yang-Han Wu, Yu-An Huang, Jie Chen, Gui-Qing Pan, Lun Hu, Zhu-Hong You, and Jian-Qiang Li
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Neural Networks, Computer ,Molecular Biology ,Information Systems - Abstract
MotivationInteraction between transcription factor (TF) and its target genes establishes the knowledge foundation for biological researches in transcriptional regulation, the number of which is, however, still limited by biological techniques. Existing computational methods relevant to the prediction of TF-target interactions are mostly proposed for predicting binding sites, rather than directly predicting the interactions. To this end, we propose here a graph attention-based autoencoder model to predict TF-target gene interactions using the information of the known TF-target gene interaction network combined with two sequential and chemical gene characters, considering that the unobserved interactions between transcription factors and target genes can be predicted by learning the pattern of the known ones. To the best of our knowledge, the proposed model is the first attempt to solve this problem by learning patterns from the known TF-target gene interaction network.ResultsIn this paper, we formulate the prediction task of TF-target gene interactions as a link prediction problem on a complex knowledge graph and propose a deep learning model called GraphTGI, which is composed of a graph attention-based encoder and a bilinear decoder. We evaluated the prediction performance of the proposed method on a real dataset, and the experimental results show that the proposed model yields outstanding performance with an average AUC value of 0.8864 +/- 0.0057 in the 5-fold cross-validation. It is anticipated that the GraphTGI model can effectively and efficiently predict TF-target gene interactions on a large scale.AvailabilityPython code and the datasets used in our studies are made available at https://github.com/YanghanWu/GraphTGI
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- 2021
13. GBDR: a Bayesian model for precise prediction of pathogenic microorganisms using 16S rRNA gene sequences
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Yu-An Huang, Zhi-An Huang, Jian-Qiang Li, Zhu-Hong You, Lei Wang, Hai-Cheng Yi, and Chang-Qing Yu
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Bacteria ,RNA, Ribosomal, 16S ,Genetics ,Computational Biology ,Humans ,Bayes Theorem ,Genes, rRNA ,Algorithms ,Biotechnology - Abstract
Background Recent evidences have suggested that human microorganisms participate in important biological activities in the human body. The dysfunction of host-microbiota interactions could lead to complex human disorders. The knowledge on host-microbiota interactions can provide valuable insights into understanding the pathological mechanism of diseases. However, it is time-consuming and costly to identify the disorder-specific microbes from the biological “haystack” merely by routine wet-lab experiments. With the developments in next-generation sequencing and omics-based trials, it is imperative to develop computational prediction models for predicting microbe-disease associations on a large scale. Results Based on the known microbe-disease associations derived from the Human Microbe-Disease Association Database (HMDAD), the proposed model shows reliable performance with high values of the area under ROC curve (AUC) of 0.9456 and 0.8866 in leave-one-out cross validations and five-fold cross validations, respectively. In case studies of colorectal carcinoma, 80% out of the top-20 predicted microbes have been experimentally confirmed via published literatures. Conclusion Based on the assumption that functionally similar microbes tend to share the similar interaction patterns with human diseases, we here propose a group based computational model of Bayesian disease-oriented ranking to prioritize the most potential microbes associating with various human diseases. Based on the sequence information of genes, two computational approaches (BLAST+ and MEGA 7) are leveraged to measure the microbe-microbe similarity from different perspectives. The disease-disease similarity is calculated by capturing the hierarchy information from the Medical Subject Headings (MeSH) data. The experimental results illustrate the accuracy and effectiveness of the proposed model. This work is expected to facilitate the characterization and identification of promising microbial biomarkers.
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- 2021
14. Profiles of Cytokinins Metabolic Genes and Endogenous Cytokinins Dynamics during Shoot Multiplication In Vitro of
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Yuan-Yuan, Li, Zhi-Gang, Hao, Shuo, Miao, Xiong, Zhang, Jian-Qiang, Li, Shun-Xing, Guo, and Yung-I, Lee
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Cytokinins ,Plant Growth Regulators ,Orchidaceae - Abstract
Shoot multiplication induced by exogenous cytokinins (CKs) has been commonly used in
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- 2021
15. ANLN and Lung Adenocarcinoma Prognosis and Immune Infiltration Research
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Jian-Qiang Li, Meihua Ru, Ying-Bo Liu, Zhi-Hui Tian, and Ivan Steve Godje Godje
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ANLN ,Lung ,medicine.anatomical_structure ,Immune infiltration ,business.industry ,Cancer research ,medicine ,Adenocarcinoma ,medicine.disease ,business - Abstract
Objective: This study aims to explore the role of aniline-actin binding protein (ANLN) in the prognosis of lung adenocarcinoma (LUAD) and its role in immune infiltration, and to provide new ideas for clinical diagnosis and treatment.Methods: In this study, we applied bioinformatics methods to analyze the expression pattern and prognostic value of ANLN in LUAD ,and confirmed its independent prognostic value through Cox analysis. TIMER was used to evaluate the correlation between ANLN and tumor infiltrating immunity. LinkedOmics was used to study the co-expressed genes and functional networks related to ANLN.The TIMER database was used to analyze the correlation between ANLN co-expressed genes and tumor infiltrating immune cells. Results: ANLN is highly expressed in most cancers. In the TCGA-LUAD cohort, ANLN was highly expressed in LUAD. ANLN was significantly related to the grade , T stage and N stage of patients with LUAD. It was verified in multiple independent queues. The high expression and highly mutation of ANLN predicts poor survival .Multivariate COX analysis showed that ANLN was an independent risk factor for survival . GSEA analysis shows that ANLN regulates cell cycle, and other pathways. The expression of ANLN was significantly correlated with the level of B cell infiltration.Conclusions: ANLN is closely related to the prognosis of patients with LUAD and tumor immune cell infiltration suggesting that ANLN is a key factor regulating the recruitment of immune cells to LUAD and may play an important role in immune.
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- 2021
16. Ultralow-Content Palladium Dispersed in Covalent Organic Framework for Highly Efficient and Selective Semihydrogenation of Alkynes
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Yuan Tao, Li Jun Sun, Jian Qiang Li, Chao Jiang, Ya Ling Fan, Zhi Gao, Wen Hui Yin, Jian Hong Li, Yu Xin Xiao, Zhiwu Yu, and Feng Luo
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010405 organic chemistry ,Composite number ,chemistry.chemical_element ,010402 general chemistry ,01 natural sciences ,0104 chemical sciences ,Catalysis ,Styrene ,Inorganic Chemistry ,chemistry.chemical_compound ,Phenylacetylene ,chemistry ,Chemical engineering ,Physical and Theoretical Chemistry ,Selectivity ,Dispersion (chemistry) ,Palladium ,Covalent organic framework - Abstract
Developing noble-metal-based catalysts with ultralow loading to achieve excellent performance for selective hydrogenation of alkynes under mild reaction conditions is highly desirable but still faces huge challenges. To this end, a SO3H-anchored covalent organic framework (COF-SO3H) as the support was deliberately designed, and then ultralow-content Pd (0.38 wt %) was loaded by a wet-chemistry immersion dispersion method. The resulting Pd0.38/COF-SO3H composite exhibits outstanding performance for the selective hydrogenation of phenylacetylene with 97.06% conversion and 93.15% selectivity to styrene under mild reaction conditions (1 bar of H2, 25 °C). Noticeably, the turnover frequency value reaches as high as 3888 h-1, which outperforms most of reported catalysts for such use. Moreover, such a catalyst also exhibits excellent activity for a series of other alkynes and high stability without obvious loss of catalytic performance after five consecutive cycles.
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- 2019
17. Fermentative production of the unnatural amino acid l-2-aminobutyric acid based on metabolic engineering
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Zhiqiang Liu, Jian-Qiang Li, Yu-Guo Zheng, Jian-Miao Xu, and Bo Zhang
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Threonine ,l-Threonine deaminase ,lcsh:QR1-502 ,Metabolic network ,Bioengineering ,medicine.disease_cause ,Leucine dehydrogenase ,Applied Microbiology and Biotechnology ,lcsh:Microbiology ,Metabolic engineering ,Fed-batch fermentation ,chemistry.chemical_compound ,Bioreactors ,Biosynthesis ,Escherichia coli ,medicine ,Gene ,chemistry.chemical_classification ,l-Leucine dehydrogenase ,Chemistry ,Aminobutyrates ,Research ,food and beverages ,Amino acid ,Biochemistry ,Fermentation ,l-2-Aminobutyric acid ,Metabolic Networks and Pathways ,Biotechnology - Abstract
Background l-2-aminobutyric acid (l-ABA) is an unnatural amino acid that is a key intermediate for the synthesis of several important pharmaceuticals. To make the biosynthesis of l-ABA environmental friendly and more suitable for the industrial-scale production. We expand the nature metabolic network of Escherichia coli using metabolic engineering approach for the production of l-ABA. Results In this study, Escherichia coli THR strain with a modified pathway for threonine-hyperproduction was engineered via deletion of the rhtA gene from the chromosome. To redirect carbon flux from 2-ketobutyrate (2-KB) to l-ABA, the ilvIH gene was deleted to block the l-isoleucine pathway. Furthermore, the ilvA gene from Escherichia coli W3110 and the leuDH gene from Thermoactinomyces intermedius were amplified and co-overexpressed. The promoter was altered to regulate the expression strength of ilvA* and leuDH. The final engineered strain E. coli THR ΔrhtAΔilvIH/Gap-ilvA*-Pbs-leuDH was able to produce 9.33 g/L of l-ABA with a yield of 0.19 g/L/h by fed-batch fermentation in a 5 L bioreactor. Conclusions This novel metabolically tailored strain offers a promising approach to fulfill industrial requirements for production of l-ABA. Electronic supplementary material The online version of this article (10.1186/s12934-019-1095-z) contains supplementary material, which is available to authorized users.
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- 2019
18. Anchoring nZVI on metal-organic framework for removal of uranium(Ⅵ) from aqueous solution
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Feng Luo, Li Xiao Yang, Yuan Tao, Hui Qiong Wu, Jian Hong Li, Jian Qiang Li, and Wen Hui Yin
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Aqueous solution ,Chemistry ,chemistry.chemical_element ,02 engineering and technology ,Uranium ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,01 natural sciences ,0104 chemical sciences ,Electronic, Optical and Magnetic Materials ,Inorganic Chemistry ,Human health ,Adsorption ,X-ray photoelectron spectroscopy ,Chemical engineering ,Nuclear industry ,Materials Chemistry ,Ceramics and Composites ,Metal-organic framework ,Physical and Theoretical Chemistry ,0210 nano-technology - Abstract
Uranium is the most radioactive element using in the nuclear industry and nuclear technology application. However, it is harmful for environment and human health due to its high toxicity and mobility. Thus designing effective material for uranium removal is highly desirable. In this paper, a novel adsorbent of nZVI@Zn-MOF-74 prepared by anchoring nZVI on Zn-MOF-74 was investigated for the removal of uranium from aqueous solutions. Impressively, nZVI was synthesized for the first time by a spraying approach in a simple and convenient manner. The experimental results indicated that nZVI@Zn-MOF-74 can significantly enhance the removal of U(VI) than both Zn-MOF-74 material and nZVI, leading to high adsorption capacity up to 348 mg/g at pH = 3 and 298 K. The origin, as unveiled by XPS, is due to both U(VI) adsorption from Zn-MOF-74 and U(VI)-to-U(IV) reduction by nZVI.
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- 2019
19. A novel treatment of refractory coronary embolism: thrombus aspiration catheter-assisted twisting wire technique
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Yi-Lun, Zou, Jian-Qiang, Li, Yong-Tai, Gong, Dang-Hui, Sun, and Yue, Li
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Refractory thrombus embolism ,Complication ,Letter To The Editor ,Percutaneous coronary intervention ,Thrombectomy - Published
- 2020
20. Pd@Zn-MOF-74: Restricting a Guest Molecule by the Open-Metal Site in a Metal–Organic Framework for Selective Semihydrogenation
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Hui Qiong Wu, Anmin Zheng, Li Xiao Yang, Ling Huang, Wen Hui Yin, Yuan Tao, Feng Luo, and Jian Qiang Li
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02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Combinatorial chemistry ,0104 chemical sciences ,Catalysis ,Styrene ,Inorganic Chemistry ,Metal ,chemistry.chemical_compound ,Phenylacetylene ,chemistry ,visual_art ,visual_art.visual_art_medium ,Molecule ,Density functional theory ,Physical and Theoretical Chemistry ,0210 nano-technology ,Selectivity - Abstract
In this work, we found that the open-metal site in a metal-organic framework (MOF) can be used to enhance such selectivity. Hydrogenation of phenylacetylene over such a catalyst enables ultrahigh styrene selectivity of 92% at full conversion with a turnover frequency of 98.1 h-1. The origin of ultrahigh selectivity, as unveiled by density functional theory calculation, is due to a coordination interaction between the open Zn(II) site and the C≡C bond of phenylacetylene.
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- 2018
21. A new azo metal-organic framework showing polycatenated 3D array and ultrahigh U(VI) removal
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Hui Qiong Wu, Li Xiao Yang, Jian Hong Li, Jian Qiang Li, Xue Feng Feng, Wen Hui Yin, Feng Luo, and Yuan Tao
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chemistry.chemical_classification ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,01 natural sciences ,Electronic equipment ,0104 chemical sciences ,Electronic, Optical and Magnetic Materials ,Ion ,Inorganic Chemistry ,chemistry.chemical_compound ,Dicarboxylic acid ,Adsorption ,chemistry ,Amide ,Polymer chemistry ,Materials Chemistry ,Ceramics and Composites ,Metal-organic framework ,Physical and Theoretical Chemistry ,0210 nano-technology ,Group 2 organometallic chemistry - Abstract
Herein we report a novel azo metal-organic framework (MOF), namely Zn2(DMF)(ADC)2(L)0.5 (ECUT-100, H2ADC=azobenzene-4,4'-dicarboxylic acid, L=N, N'-di(pyridin-4-yl)naphthalene-1,4-dicarboxamide), showing a polycatenated 3D array of interlaced 2D bilayers. Without any pre-treatment the as-synthesized ECUT-100 samples effectively adsorb U(VI), leading to the ultrahigh adsorption capacity up to 381 mg/g. This value is greatly higher than that observed in most established porous adsorbents. The origin is primarily due to the free standing azo and amide groups from ADC2- and L ligands that may provide special interactions with U(VI) ions.
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- 2018
22. Hybrid Catalyst of a Metal–Organic Framework, Metal Nanoparticles, and Oxide That Enables Strong Steric Constraint and Metal–Support Interaction for the Highly Effective and Selective Hydrogenation of Cinnamaldehyde
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Jian Qiang Li, Hui-Qiong Wu, Li-Xiao Yang, Heng-Ya Gao, Feng Luo, Wen-Hui Yin, and Yuan Tao
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Steric effects ,Cinnamyl alcohol ,Chemistry ,Oxide ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Cinnamaldehyde ,0104 chemical sciences ,Catalysis ,Inorganic Chemistry ,Metal ,chemistry.chemical_compound ,Adsorption ,Chemical engineering ,visual_art ,visual_art.visual_art_medium ,Physical and Theoretical Chemistry ,0210 nano-technology ,Selectivity - Abstract
In this work, we designed a hybrid catalyst composed of a metal–organic framework (MOF), Pt nanoparticles (NPs), and ferric oxide, namely, Co-MOF-74@(Pt@Fe2O3), which enables not only high turnover frequencies of up to 245.7 h–1 but also ultrahigh 100% selectivity toward cinnamyl alcohol in the hydrogenation of cinnamaldehyde under mild conditions. This excellent performance is attributed to the fact that such a hybrid catalyst enables not only strong steric constraint to provide the favored C═O adsorption of cinnamaldehyde but also strong metal–support interaction to lower the electron density of Pt NPs.
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- 2018
23. Metal-organic framework containing both azo and amide groups for effective U(VI) removal
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Lu-Fang Ma, Xue Feng Feng, Jian Qiang Li, Yuan Tao, Li Xiao Yang, Wen Hui Yin, Feng Luo, and Hui Qiong Wu
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Inorganic chemistry ,chemistry.chemical_element ,Sorption ,02 engineering and technology ,Uranium ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,01 natural sciences ,0104 chemical sciences ,Electronic, Optical and Magnetic Materials ,Ion ,Inorganic Chemistry ,chemistry.chemical_compound ,Adsorption ,chemistry ,Amide ,Materials Chemistry ,Ceramics and Composites ,Metal-organic framework ,Physical and Theoretical Chemistry ,0210 nano-technology ,Chemical adsorption ,Group 2 organometallic chemistry - Abstract
Uranium is not only a radioactive element but also an important nuclear-energy source. Thus the design of material for effective uranium adsorption is highly desirable from both environmental and energy considerations. In this work, a new azo-MOF was explored such use. It shows excellent U(VI) removal performance with the adsorption capacity up to 200 mg/g. The adsorption, as disclosed by the adsorption kinetics, is dominated by chemical adsorption, mainly due to coordination interaction between azo/amide and U(VI) ions. The results suggest that design of material with free-standing azo or amide groups benefits to U(VI) removal.
- Published
- 2018
24. Functionalizing a Metal–Organic Framework by a Photoassisted Multicomponent Postsynthetic Modification Approach Showing Highly Effective Hg(II) Removal
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Yang Yang Xiong, Xiao Lan Tong, Jian Qiang Li, Li Xiao Yang, Hui Qiong Wu, Wen Hui Yin, Feng Luo, and Yuan Tao
- Subjects
Inorganic Chemistry ,Adsorption ,Chemistry ,Inorganic chemistry ,02 engineering and technology ,Physical and Theoretical Chemistry ,010402 general chemistry ,021001 nanoscience & nanotechnology ,0210 nano-technology ,01 natural sciences ,0104 chemical sciences - Abstract
We present here the first use of a photoassisted multicomponent postsynthetic modification method to anchor a ZIF-90 scaffold with a pyrimidinethione fragment. The resultant materials, namely, ZIF-90-THP and ZIF-90-THF, show ultrahigh Hg(II) adsorption capacity values of up to 596 and 403 mg/g, respectively, relative to the pristine ZIF-90, which just affords a corresponding value of 47 mg/g, suggesting a 12.7- and 8.6-fold enhancement in the Hg(II) adsorption capacity.
- Published
- 2018
25. Applying MOF+ technique for in situ preparation of a hybrid material for hydrogenation reaction
- Author
-
Ming Biao Luo, Jian Qiang Li, Hui Qiong Wu, Li Xiao Yang, Feng Luo, Wen Hui Yin, and Yuan Tao
- Subjects
In situ ,chemistry.chemical_classification ,Materials science ,Alkene ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,0104 chemical sciences ,Catalysis ,Inorganic Chemistry ,chemistry.chemical_compound ,Chemical engineering ,Phenylacetylene ,chemistry ,Hydrogenation reaction ,0210 nano-technology ,Porosity ,Hybrid material - Abstract
In this study, we present the first case of applying the MOF+ technique for in situ preparation of a hybrid material, namely, Zn-MOF-74@ (Pd@Fe2O3). This as-synthesized material can well maintain both the integrity of the framework and porosity. Notably, Zn-MOF-74@(Pd@Fe2O3) exhibits outstanding catalytic performance in the hydrogenation reaction of alkene and semihydrogenation reaction of phenylacetylene, thus providing a new guideline for the design of MOF-based hybrid materials for catalytic purpose.
- Published
- 2018
26. The MOF+Technique: A Significant Synergic Effect Enables High Performance Chromate Removal
- Author
-
Ming Biao Luo, Feng Luo, Jian Qiang Li, Yang Yang Xiong, Hui Qiong Wu, and Xue Feng Feng
- Subjects
Materials science ,Aqueous solution ,Chromate conversion coating ,Chemistry ,Scanning electron microscope ,Inorganic chemistry ,General Chemistry ,02 engineering and technology ,General Medicine ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Catalysis ,0104 chemical sciences ,Adsorption ,Chemical engineering ,X-ray photoelectron spectroscopy ,Transmission electron microscopy ,0210 nano-technology ,Porosity - Abstract
Significant synergic effect from metal-organic framework (MOF) and Fe2SO4, so-called MOF+ technique, is for the first time exploited to remove toxic chromate from aqueous solution. The results show that relative to the pristine MOF samples without detectable chromate removal, MOF+ method enables super-performance, giving a 796 Cr mg/g adsorption capacity. The value is almost eight-fold bigger than the best value established in MOF adsorbents, and presents the highest one among all repored porous adsorbents for such use until now. The adsorption mechanism, unlike an anion-exchange process that dominates the chromate removal in all reported MOF adsorbents, as unveiled by X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), and transmission electron microscopy (TEM), is due to the surface enrichment of abundant Fe0.75Cr0.25(OH)3 nanospheres on MOF samples. This study outlines a new guideline for designing MOFs with ultrahigh removal capacity toward chromate.
- Published
- 2017
27. U=O activation in uranyl-organic framework through solid-liquid reaction: A powerful tool to modulate electronic and magnetic structure
- Author
-
Jian Hong Li, Sheng Dong Zhang, Feng Luo, and Jian Qiang Li
- Subjects
Work (thermodynamics) ,Materials science ,Magnetic structure ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,Uranyl ,01 natural sciences ,0104 chemical sciences ,Electronic, Optical and Magnetic Materials ,Inorganic Chemistry ,chemistry.chemical_compound ,chemistry ,Homogeneous ,Materials Chemistry ,Ceramics and Composites ,Photocatalysis ,Physical chemistry ,Molecule ,Physical and Theoretical Chemistry ,0210 nano-technology ,Solid liquid ,Diborane - Abstract
Activation of the extremely inert U O bond of uranyl group is presents not only a high scientific challenge, but also a powerful tool to modify the physical and chemical properties of materials with unique electronic and magnetic features. Distinct from all homogeneous methods of U O activation reported in the literature, this work presents, for the first time, a solid-liquid reaction through post-modification approach on uranyl-organic framework to generate stable U–O activated metal-organic framework. Two different molecules such as B-chlorocatecholborane (Cl-BCat) and diborane pinacolate ((Bpin)2, pin = pinacolate) were used to carry out this task, giving activating efficiency of 37% for Cl-BCat and 50% for (Bpin)2, respectively. Impressively, this U O activation directly leads to significant change in the physical and chemical properties, for example, a diamagnetic-to-paramagnetic transformation and significant reduction in photocatalytic oxidation efficiency, as compared to the properties of pristine MOF.
- Published
- 2021
28. Direct extraction of U(VI) from alkaline solution and seawater via anion exchange by metal-organic framework
- Author
-
Le Zhang, Chang Sheng Yan, Jian Qiang Li, Le Le Gong, Heng Ya Gao, Yang Yang Xiong, Hui Qiong Wu, Xue Feng Feng, and Feng Luo
- Subjects
Ion exchange ,Chemistry ,General Chemical Engineering ,Inorganic chemistry ,Extraction (chemistry) ,Cationic polymerization ,chemistry.chemical_element ,02 engineering and technology ,General Chemistry ,Uranium ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Industrial and Manufacturing Engineering ,0104 chemical sciences ,Adsorption ,Environmental Chemistry ,Seawater ,Metal-organic framework ,0210 nano-technology ,Selectivity - Abstract
Directly extracting uranium from alkaline solution and seawater through an effective and economical method is still a challenging task. In this work, we for the first time propose a method of anionic exchange, based on a cationic MOF (metal-organic framework) adsorbent, namely Co-SLUG-35, to directly extract U(VI) from alkaline solution and seawater (South China Sea). The U(VI) adsorption experiments indicates that the EDS2− anions in Co-SLUG-35 can be completely replaced by U(VI) ions in an anionic manner, leading to an adsorption capability of 118 mg/g from alkaline U(VI) solution and excellent extraction efficiency of 1.05 mg/g from 1 L actual seawater in the concentration of 5.35 ppb. Most importantly, unlike other MOFs where degassing is primarily needed, however the use of present MOF need not any pretreatment. Moreover, ultrahigh selectivity towards U(VI) ions even over CrO42− and Cl− ions is also observed in Co-SLUG-35, suggesting its superior potential in extraction of uranium from seawater.
- Published
- 2017
29. Using MOF-74 for Hg2+ removal from ultra-low concentration aqueous solution
- Author
-
Yang Yang Xiong, Le Zhang, Pan Pan Meng, Xue Feng Feng, Li Na Meng, Ming Biao Luo, Le Le Gong, Feng Luo, and Jian Qiang Li
- Subjects
Chemical substance ,Inorganic chemistry ,chemistry.chemical_element ,Nanotechnology ,02 engineering and technology ,010402 general chemistry ,01 natural sciences ,law.invention ,Ion ,Inorganic Chemistry ,Adsorption ,Magazine ,law ,Materials Chemistry ,Physical and Theoretical Chemistry ,Volume concentration ,Pollutant ,Aqueous solution ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,0104 chemical sciences ,Electronic, Optical and Magnetic Materials ,Mercury (element) ,chemistry ,Ceramics and Composites ,0210 nano-technology - Abstract
Mercury (Hg2+) ions have very high toxicity and widely spread as environmental pollutants. At present, many efforts have been taken to remove the hazardous materials of mercury(II) by adsorption, and it is highly desirable to develop a novel adsorbent with high adsorptive capacities. However it is still a big challenge to remove the ultra-low-concentration mercury ions from water. In this paper, MOF-74-Zn is explored for such function, showing high removal rate of Hg(II) from water without any pretreatment, especially for the ultra-trace Hg(II) ions in the ppb magnitude with the removal rate reaching to 54.48%, 69.71%, 72.26% when the initial concentration of Hg(II) is 20ppb, 40ppb, 50ppb, respectively.
- Published
- 2017
30. Synthesis, crystal structure, DFT analysis and fungicidal activity of a novel series O-substituted trifluoroatrolactamide derivatives
- Author
-
Hui-Hui Yang, Cong Zhu, Lei Tian, Can Cui, Jian-Qiang Li, Rui Wu, and Wei-Guang Zhao
- Subjects
0301 basic medicine ,Pyricularia ,biology ,010405 organic chemistry ,Stereochemistry ,Chemistry ,Organic Chemistry ,Fluorine-19 NMR ,Crystal structure ,Carbon-13 NMR ,biology.organism_classification ,01 natural sciences ,0104 chemical sciences ,Analytical Chemistry ,Inorganic Chemistry ,Fungicide ,03 medical and health sciences ,030104 developmental biology ,Proton NMR ,Density functional theory ,Spectroscopy ,Monoclinic crystal system - Abstract
A series of O-substituted trifluoroatrolactamide derivatives has been synthesized and fully characterized by 1H NMR, 13C NMR, 19F NMR, HRMS and X-ray diffraction analyses. The fungicidal activity of these compounds was evaluated and the results showed that some of them exhibited potent in vitro fungicidal activity against Erysiphe graminis and Pyricularia oryzae. Their structure-property relationships were investigated using density functional theory calculations. The X-ray crystal structure of one of these compounds adopted a monoclinic space group with the following unit cell parameters: a = 24.285 (13) A, b = 9.006 (5) A, c = 9.794 (5) A, β = 92.110 (9)o, V = 2140.6 (19) A3 and Z = 4. A comparison of these experimental results with the theoretical values revealed that there was good agreement between the two sets of data. The subsequent biological evaluation of these compounds showed that some of them exhibited potent in vitro fungicidal activity against Erysiphe graminis and Pyricularia oryzae.
- Published
- 2017
31. Nest survival rate of Reeves's pheasant(Syrmaticus reevesii) based on artificial nest experiments
- Author
-
Xu Luo, Yu-Ze Zhao, Jing Ma, Jian-Qiang Li, and Ji-Liang Xu
- Subjects
Syrmaticus reevesii ,Reeves's pheasant ,lcsh:Zoology ,Artificial nest experiments ,lcsh:QL1-991 ,Nest survival rate - Abstract
To explore the nest survival rate of Reeves's pheasant(Syrmaticus reevesii) and the nest-site factors that affect it, we conducted artificial nest experiments with reference to natural nests at Dongzhai National Nature Reserve(DNNR), Henan Province and Pingjingguan, Hubei Province from April to June 2014 simulating the situation in its early and later breeding season. We also determined distance characteristics of the nest sites using ArcGIS 10.0. Nest survival models were constructed in Program MARK for data analysis. Results indicated that in the early breeding season, the apparent survival rate(ASR) in DNNR(52.4%) was significantly greater than that in Pingjingguan(13.5%), and the ASR in the later breeding season in DNNR(26.7%) was not indistinctively correlated with Pingjingguan(3.2%). The daily survival rate(DSR) in the later breeding season was 93.8% in DNNR and 92.0% in Pingjingguan, respectively. The DSRs were both negatively correlated with nest distance to forest edges and settlements. The DSR in Pingjingguan was positively correlated with nest distance to paths and negatively correlated with nest distance to water sources. However, the DSR in DNNR was negatively correlated with nest distance to paths but positively correlated with nest distance to water sources.
- Published
- 2017
32. Photoswitching storage of guest molecules in metal–organic framework for photoswitchable catalysis: exceptional product, ultrahigh photocontrol, and photomodulated size selectivity
- Author
-
Feng Luo, Jian Qiang Li, Chang Sheng Yan, Zhiqiang Liu, Xue Feng Feng, Ming Biao Luo, Anmin Zheng, Le Le Gong, Lu-Fang Ma, and Wan Ting Yao
- Subjects
chemistry.chemical_classification ,Renewable Energy, Sustainability and the Environment ,Nanotechnology ,02 engineering and technology ,General Chemistry ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Aldehyde ,0104 chemical sciences ,Catalysis ,Adsorption ,chemistry ,Size selectivity ,Molecule ,General Materials Science ,Density functional theory ,Metal-organic framework ,0210 nano-technology - Abstract
MOF materials, as new catalysts, show high catalytic activity and size-, regio-, and stereo-selectivity. However, artificially controlling their catalytic process by convenient external stimulus such as light is still unexploited. Such photocontrol over an organic reaction may enable switchable catalytic activities and/or selectivities, consequently producing desired products from a pool of building blocks according to the order and type of stimuli applied. In this study, we present a novel MOF catalyst, which not only offers ultrahigh photocontrol with the on/off ratio as high as 407, but also displays disparate photomodulation in reaction kinetics towards various aldehyde substrates in light of their sizes, thus creating the first example of MOFs showing photoswitchable catalysis. The origin, as unveiled by photoswitching adsorption experiments and density functional theory calculations, is due to photoswitching storage of guest molecules in the metal–organic framework (MOF).
- Published
- 2017
33. Intravascular ultrasound-guided 'extended' reverse controlled antegrade and retrograde subintimal tracking technique using a cutting balloon for recanalizing chronic coronary total occlusion with a side branch
- Author
-
Yong-Tai, Gong, Jian-Qiang, Li, Li, Sheng, Dang-Hui, Sun, and Yue, Li
- Subjects
Chronic total occlusion ,Reverse controlled antegrade and retrograde tracking technique ,Cutting balloon ,Intravascular ultrasound ,Letter To The Editor ,Percutaneous coronary intervention - Published
- 2019
34. Dual specific CD19/CD22-targeted chimeric antigen receptor T-cell therapy for refractory diffuse large B-cell lymphoma: A case report
- Author
-
Rui‑Xia Liu, Jin‑Yuan Ho, Mei‑Rong Zheng, Lihong Liu, Lin Wang, Jian‑Qiang Li, Na Kuang, Chen Huang, and Hui‑Chao Zhang
- Subjects
0301 basic medicine ,Oncology ,Cancer Research ,medicine.medical_specialty ,diffuse large B-cell lymphoma ,03 medical and health sciences ,0302 clinical medicine ,Refractory ,immune system diseases ,hemic and lymphatic diseases ,Internal medicine ,medicine ,Refractory Diffuse Large B-Cell Lymphoma ,CD22 ,therapy ,CD19 ,business.industry ,Cancer ,cytokine release syndrome ,Articles ,chimeric antigen receptor T cell ,medicine.disease ,Chimeric antigen receptor ,Lymphoma ,Cytokine release syndrome ,030104 developmental biology ,030220 oncology & carcinogenesis ,Chimeric Antigen Receptor T-Cell Therapy ,business ,human activities ,Diffuse large B-cell lymphoma - Abstract
Clinical trials of chimeric antigen receptors (CARs) targeting CD19 have produced impressive results in hematological malignancies, including diffuse large B-cell lymphoma (DLBCL). However, a notable number of patients with DLBCL fail to achieve remission after CD19 CAR T-cell therapy and may therefore require a dual targeted CAR T-cell therapy. A 31-year-old man with refractory DLBCL was assessed in the present case report. The patient was treated with sequential infusion of single CD19 CAR T cells followed by dual CD19/CD22-targeted CAR T cells. The outcome was that the patient achieved partial remission after the first single CD19 CAR T-cell infusion and complete remission after the dual CD19/CD22-targeted CAR T-cell infusion. Grade 1 cytokine release syndrome (CRS) was observed after the single CD19 CAR T-cell infusion, while grade 3 CRS and hemophagocytic syndrome were observed after the dual targeted CAR T-cell infusion, but these adverse effects alleviated after the treatments. To the best of our knowledge, the present case report is the first to describe the successful application of dual CD19/CD22-targeted CAR T-cell therapy for the treatment of refractory DLBCL. The report suggests that dual CD19/CD22-targeted CAR T-cell therapy may represent a promising option for the treatment of refractory DLBCL; however, caution should be taken due to potential CRS development.
- Published
- 2019
35. Long Noncoding RNA MALAT1 Reduces Chemosensitivity of Non-Small Cell Lung Cancer Cells via Stimulation of the Autophagy Pathway
- Author
-
Xiao-Ling Gao, Dong-Dong An, Zhi-Mei Jia, Fang-Fang Zhao, Jian-Qiang Li, Bei Wang, Hui Zhao, Er-Jing Cheng, Ya-Qiong Huang, Jiao-Jiao Yang, and Shu-Juan Wang
- Published
- 2019
36. Facile synthesis, crystal structure and antifungal activity of dimethylated trifluoroatrolactamide derivatives
- Author
-
Hui-Hui Yang, Jian-Qiang Li, Cong Zhu, Can Cui, Xing-Hai Liu, and Wei-Guang Zhao
- Subjects
Antifungal ,010405 organic chemistry ,medicine.drug_class ,Chemistry ,General Chemistry ,Fluorine-19 NMR ,Crystal structure ,Carbon-13 NMR ,010402 general chemistry ,01 natural sciences ,Combinatorial chemistry ,0104 chemical sciences ,Methylating Agent ,medicine ,Proton NMR - Abstract
A series of novel substituted 3,3,3-trifluoro-2-methoxy-N-methyl-N,2-diphenylpropanamides were synthesized from α-hydroxyacetamide using CH3I as the methylating agent. Their chemical structures were characterized by 1H NMR, 13C NMR, 19F NMR, and HRMS X-ray analysis. The dimethylated trifluoroatrolactamide exhibited moderate antifungal activity.
- Published
- 2016
37. Structured Analysis on the Group Decision-Making Hierarchy of the Optimal Mechanism Construction of Top Racing Management
- Author
-
Jia-Peng Xu, Jun Pu, Jian-Qiang Li, and Rui-Yang Ma
- Subjects
Computational Mathematics ,Hierarchy ,Structured analysis ,Operations research ,Computer science ,Optimal mechanism ,General Materials Science ,General Chemistry ,Electrical and Electronic Engineering ,Condensed Matter Physics ,Simulation ,Group decision-making - Published
- 2016
38. Diurnal brooding behavior of long-tailed tits (Aegithalos caudatus glaucogularis)
- Author
-
Jin YU, Peng-Cheng WANG, Lei LÜ, Zheng-Wang ZHANG, Yong WANG, Ji-Liang XU, Jian-Qiang LI, Bo XI, Jia-Gui ZHU, and Zhi-Yong DU
- Subjects
Long-tailed tit ,lcsh:Zoology ,lcsh:QL1-991 ,Aegithalos caudatus glaucogularis ,Brooding ,Early nestling stage ,Daytime - Abstract
Brooding is a major breeding investment of parental birds during the early nestling stage, and has important effects on the development and survival of nestlings. Investigating brooding behavior can help to understand avian breeding investment strategies. From January to June in 2013 and 2014, we studied the brooding behaviors of long-tailed tits (Aegithalos caudatus glaucogularis) in Dongzhai National Nature Reserve, Henan Province, China. We analyzed the relationships between parental diurnal brooding duration and nestling age, brood size, temperature, relative breeding season, time of day and nestling frequencies during brooding duration. Results showed that female and male long-tailed tit parents had different breeding investment strategies during the early nestling stage. Female parents bore most of the brooding investment, while male parents performed most of the nestling feedings. In addition, helpers were not found to brood nestlings at the two cooperative breeding nests. Parental brooding duration was significantly associated with the food delivered to nestlings (F=86.10, df=1, 193.94, P
- Published
- 2016
39. In situ identification and absolute separation of small molecules by single crystal X-ray diffraction in metal–organic frameworks
- Author
-
Feng Luo, Chang Sheng Yan, Jian Qiang Li, Le Le Gong, Pan Pan Meng, Heng Ya Gao, Li Na Meng, and Le Zhang
- Subjects
In situ ,integumentary system ,Analytical chemistry ,Absolute (perfumery) ,02 engineering and technology ,General Chemistry ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,01 natural sciences ,Small molecule ,0104 chemical sciences ,Propanol ,chemistry.chemical_compound ,Crystallography ,chemistry ,X-ray crystallography ,General Materials Science ,Metal-organic framework ,Methanol ,0210 nano-technology ,Single crystal - Abstract
This work presents an in situ method, similar to the ‘crystalline sponge’ method, to accurately identify and absolutely separate small volatile organic molecules (such as methanol, ethanol, propanol and DMF).
- Published
- 2016
40. Design, synthesis and effect of the introduction of a propargyloxy group on the fungicidal activities of 1-substituted phenoxypropan-2-amino valinamide carbamate derivatives
- Author
-
Jian-Qiang Li, Zhi-Peng Wang, Wei-Guang Zhao, and Yang Gao
- Subjects
0301 basic medicine ,chemistry.chemical_classification ,Carbamate ,010405 organic chemistry ,General Chemical Engineering ,medicine.medical_treatment ,Carboxylic acid ,General Chemistry ,01 natural sciences ,0104 chemical sciences ,Amino acid ,Cell wall ,Fungicide ,03 medical and health sciences ,chemistry.chemical_compound ,030104 developmental biology ,chemistry ,Amide ,medicine ,Bioassay ,Organic chemistry ,Cellulose - Abstract
The cell walls of oomycetes are composed of cellulose, making cellulose synthase enzymes good targets for carboxylic acid amide fungicides. Valinamide carbamates are amino acid fungicides that represent excellent alternatives to conventional synthetic pesticides in terms of their ability to reduce the negative impacts of these compounds on human health and the environment. In a continuation of our research towards the development of new cellulose synthase inhibitors, we have developed a series of “stretched” analogues of iprovalicarb by the introduction of an additional OCH2 linker. The bioassay results indicated that compounds containing a small group at the para-position of phenyl gave excellent fungicidal activities with EC50 values ranging from 0.59 to 2.06 μmol L−1. Most notably, the introduction of a propargyloxy group led to a pronounced increase in the fungicidal activity. Furthermore, compound 7o bearing a propargyloxy group was identified as the most promising candidate because of its excellent fungicidal potency against oomycete diseases and good fungicidal activity against non-oomycete diseases.
- Published
- 2016
41. Lanthanide separation using size-selective crystallization of Ln-MOFs
- Author
-
Jian Qiang Li, Feng Luo, Pan Pan Meng, Hui Qiong Wu, Heng Ya Gao, Xue Feng Feng, Yang Yang Xiong, Wen Li Peng, and Chang Sheng Yan
- Subjects
Lanthanide ,Chemistry ,Inorganic chemistry ,Metals and Alloys ,02 engineering and technology ,General Chemistry ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Highly selective ,01 natural sciences ,Catalysis ,0104 chemical sciences ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,law.invention ,Ion ,law ,Materials Chemistry ,Ceramics and Composites ,Size selective ,Crystallization ,0210 nano-technology - Abstract
Herein, we report an elaborate method, size-selective crystallization of Ln-MOFs, to isolate lanthanide (Ln) ions. Herein, 13 lanthanide ions, except for the radioactive Pm(iii) ion, were separated by four types of Ln-MOFs: type I (La-Pr), type II (Nd-Eu), type III (Gd-Ho), and type IV (Er-Lu). Further systemic investigation also suggested the highly selective separation of lanthanide ions by this method.
- Published
- 2017
42. Constructing PtI@COF for semi-hydrogenation reactions of phenylacetylene
- Author
-
Li Wang, Ya Ling Fan, Feng Luo, Yu Xin Xiao, Jian Qiang Li, Jian Hong Li, Zhi Gao, Li Xiao Yang, Yuan Tao, Jian Bo Xiong, and Zhiwu Yu
- Subjects
Reaction conditions ,Materials science ,Metal ions in aqueous solution ,Composite number ,02 engineering and technology ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,01 natural sciences ,0104 chemical sciences ,Electronic, Optical and Magnetic Materials ,Catalysis ,Styrene ,Inorganic Chemistry ,chemistry.chemical_compound ,Chemical engineering ,chemistry ,Phenylacetylene ,Materials Chemistry ,Ceramics and Composites ,Physical and Theoretical Chemistry ,0210 nano-technology ,Selectivity - Abstract
The great efforts have been devoted to fabricate excellent hydrogenation catalysts owing to the broad applications in industrial fields. However, the preparation processes of traditional hydrogenation catalysts are often complicated. Herein, mono-valence PtI@COF was synthesized as a catalyst for semi-hydrogenation of phenylacetylene for the first time. The easily prepared SO3H-linked COF possesses a two-dimensional eclipsed layered-sheet structure, making its incorporation with metal ions feasible. The as-prepared PtI@COF composite exhibits excellent performance for semi-hydrogenation phenylacetylene with 93.5% conversion and 90.2% selectivity to styrene under mild reaction conditions (1 bar H2, 25 °C) within 20 min. It’s worth noting that the turnover frequency (TOF) value reaches at 3965 h-1, which outperforms most of recently reported excellent Pt-based catalysts for this reaction.
- Published
- 2020
43. Effect of Heat Treatment on the Microstructure and Fracture Behaviors of a Ni–Cr–Fe Superalloy
- Author
-
Jia-Huan Chen, Jian-Qiang Li, Yang Shen, Yuan-fei Cai, and Zhiyuan Zhu
- Subjects
Superalloy ,Materials science ,Metallurgy ,Fracture (geology) ,General Materials Science ,Condensed Matter Physics ,Microstructure - Published
- 2020
44. Applying MOF
- Author
-
Yuan, Tao, Hui Qiong, Wu, Jian Qiang, Li, Li Xiao, Yang, Wen Hui, Yin, Ming Biao, Luo, and Feng, Luo
- Abstract
In this study, we present the first case of applying the MOF+ technique for in situ preparation of a hybrid material, namely, Zn-MOF-74@ (Pd@Fe2O3). This as-synthesized material can well maintain both the integrity of the framework and porosity. Notably, Zn-MOF-74@(Pd@Fe2O3) exhibits outstanding catalytic performance in the hydrogenation reaction of alkene and semihydrogenation reaction of phenylacetylene, thus providing a new guideline for the design of MOF-based hybrid materials for catalytic purpose.
- Published
- 2018
45. Prediction of Potential Small Molecule-Associated MicroRNAs Using Graphlet Interaction
- Author
-
Na-Na Guan, Ya-Zhou Sun, Zhong Ming, Jian-Qiang Li, and Xing Chen
- Subjects
0301 basic medicine ,Association score ,Pharmacology ,similarity calculation ,microRNA ,Computer science ,lcsh:RM1-950 ,small molecule ,Computational biology ,association prediction ,graphlet interaction ,Small molecule ,Cross-validation ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,lcsh:Therapeutics. Pharmacology ,Similarity (network science) ,030220 oncology & carcinogenesis ,Pharmacology (medical) ,Original Research - Abstract
MicroRNAs (miRNAs) have been proved to be targeted by the small molecules recently, which made using small molecules to target miRNAs become a possible therapy for human diseases. Therefore, it is very meaningful to investigate the relationships between small molecules and miRNAs, which is still yet in the newly-developing stage. In this paper, we presented a prediction model of Graphlet Interaction based inference for Small Molecule-MiRNA Association prediction (GISMMA) by combining small molecule similarity network, miRNA similarity network and known small molecule-miRNA association network. This model described the complex relationship between two small molecules or between two miRNAs using graphlet interaction which consists of 28 isomers. The association score between a small molecule and a miRNA was calculated based on counting the numbers of graphlet interaction throughout the small molecule similarity network and the miRNA similarity network, respectively. Global and two types of local leave-one-out cross validation (LOOCV) as well as five-fold cross validation were implemented in two datasets to evaluate GISMMA. For Dataset 1, the AUCs are 0.9291 for global LOOCV, 0.9505, and 0.7702 for two local LOOCVs, 0.9263 ± 0.0026 for five-fold cross validation; for Dataset 2, the AUCs are 0.8203, 0.8640, 0.6591, and 0.8554 ± 0.0063, in turn. In case study for small molecules, 5-Fluorouracil, 17β-Estradiol and 5-Aza-2'-deoxycytidine, the numbers of top 50 miRNAs predicted by GISMMA and validated to be related to these three small molecules by experimental literatures are in turn 30, 29, and 25. Based on the results from cross validations and case studies, it is easy to realize the excellent performance of GISMMA.
- Published
- 2018
46. HIGH-TEMPERATURE FRICTION AND WEAR BEHAVIOR OF A NI-BASED VALVE ALLOY
- Author
-
Jian-Qiang Li, Yuan-fei Cai, Jia-Huan Chen, and Zhiyuan Zhu
- Subjects
010302 applied physics ,Friction coefficient ,Materials science ,Metallurgy ,Alloy ,chemistry.chemical_element ,02 engineering and technology ,Surfaces and Interfaces ,engineering.material ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,01 natural sciences ,Surfaces, Coatings and Films ,Superalloy ,Nickel ,chemistry ,Exhaust valve ,0103 physical sciences ,Materials Chemistry ,engineering ,0210 nano-technology - Abstract
This study explored the friction and wear behavior of a Ni-based exhaust valve at high temperatures. Nickel-based superalloy was used with two types of processing states: the original forged sample and the sample under the standard T1 heat treatment. At room temperature and a loading force of 10[Formula: see text]N, the average friction coefficient of the T1 heat-treated specimen is 0.61, which was lower than that of the forged sample (0.78). The wear rate of this specimen was also lower than that of the forged sample at the same temperature and loading force. Thus, T1 heat treatment can significantly improve the wear resistance of the alloy because of [Formula: see text] phase and carbides. The wear rate was the minimum at 550∘C and increased again at 750∘C dominated by the formation and flake-off of the oxide film.
- Published
- 2019
47. Quantum state representation based on combinatorial Laplacian matrix of star-relevant graph
- Author
-
Xiu-Bo Chen, Yixian Yang, and Jian-Qiang Li
- Subjects
FOS: Physical sciences ,Astrophysics::Cosmology and Extragalactic Astrophysics ,Strength of a graph ,Distance-regular graph ,Theoretical Computer Science ,law.invention ,Combinatorics ,law ,Line graph ,Astrophysics::Solar and Stellar Astrophysics ,Electrical and Electronic Engineering ,Mathematical Physics ,Astrophysics::Galaxy Astrophysics ,Complement graph ,Mathematics ,Quantum Physics ,Voltage graph ,Statistical and Nonlinear Physics ,Mathematical Physics (math-ph) ,Butterfly graph ,Electronic, Optical and Magnetic Materials ,Modeling and Simulation ,Signal Processing ,Cubic graph ,Astrophysics::Earth and Planetary Astrophysics ,Quantum Physics (quant-ph) ,Null graph ,MathematicsofComputing_DISCRETEMATHEMATICS - Abstract
In this paper the density matrices derived from combinatorial Laplacian matrix of graphs is considered. More specifically, the paper places emphasis on the star-relevant graph, which means adding certain edges on peripheral vertices of star graph. Initially, we provide the spectrum of the density matrices corresponding to star-like graph (i.e., adding an edge on star graph) and present that the Von Neumann entropy increases under the graph operation (adding an edge on star graph) and the graph operation cannot be simulated by local operation and classical communication (LOCC). Subsequently, we illustrate the spectrum of density matrices corresponding to star-alike graph (i.e., adding one edge on star-like graph) and exhibit that the Von Neumann entropy increases under the graph operation (adding an edge on star-like graph) and the graph operation cannot be simulated by LOCC. Finally, the spectrum of density matrices corresponding to star-mlike graph (i.e., adding m nonadjacent edges on the peripheral vertices of star graph) is demonstrated and the relation between the graph operation and Von Neumann entropy, LOCC is revealed in this paper.
- Published
- 2015
48. Adsorption Isotherm and Kinetics Studies of Chemical Modified Waste Corn Stalk by Urea and Microwave for Removal of Lead(II)
- Author
-
Bo Zhou, Dushu Huang, Heping Yan, Yunhui Long, Qingshan Pan, Xianlan Chen, Shijuan Xu, Wei Liu, Na Wu, Jing Wang, Ling Shi, Gao-Zhang Gou, Meigui Ma, and Jian Qiang Li
- Subjects
chemistry.chemical_compound ,Chromatography ,chemistry ,Stalk ,Kinetics ,Urea ,General Chemistry ,Sorption isotherm ,Microwave ,Nuclear chemistry - Published
- 2015
49. Ultrafast high-performance extraction of uranium from seawater without pretreatment using an acylamide- and carboxyl-functionalized metal–organic framework
- Author
-
Li Long Dang, Jian Qiang Li, Shu Juan Liu, Feng Luo, Ling Ling Wang, Ming Biao Luo, and Xiao Liu Wu
- Subjects
chemistry ,Renewable Energy, Sustainability and the Environment ,Environmental chemistry ,Inorganic chemistry ,Extraction (chemistry) ,chemistry.chemical_element ,Artificial seawater ,General Materials Science ,Seawater ,Metal-organic framework ,General Chemistry ,Uranium - Abstract
Extraction of uranium from seawater is very important to overcome the growing crisis in the sustainable development of energy, and consequently has attracted an enormous amount of attention. Herein, we report the application of MOF materials in the extraction of uranium from seawater. Without any pre-treatment and within one minute, this MOF material shows a one-off extraction efficiency of 0.53 mg g−1 from 1 L artificial seawater in the concentration of 6 ppb, suggesting its significant potential for the extraction of uranium from seawater. This significant ability is mainly dependent on free standing carboxyl groups in the MOF channel that coordinate to UO2+ ions via the U–O coordination bond.
- Published
- 2015
50. High-performance Hg2+ removal from ultra-low-concentration aqueous solution using both acylamide- and hydroxyl-functionalized metal–organic framework
- Author
-
Jian Qiang Li, Ming Biao Luo, Feng Luo, Wei Na Zhou, Jing Li Chen, Hai Lu Lin, Shu Juan Liu, and Li Long Dang
- Subjects
Aqueous solution ,Adsorption ,chemistry ,Renewable Energy, Sustainability and the Environment ,Inorganic chemistry ,chemistry.chemical_element ,General Materials Science ,Metal-organic framework ,General Chemistry ,Volume concentration ,Mercury (element) - Abstract
Mercury (Hg2+), even an ultra-low-concentration amount in water, presents a serious environmental concern. Thus, the removal, especially Hg(II) content at the ultratrace levels (ppb), from water is still challenging. In this work, without any pretreatment, anovel MOF material can act as a high-capacity and collectable adsorbent for the removal of Hg(II) from water, especially for ultratrace Hg2+ ions in the ppb magnitude, mainly due to a combined effect from the pore walls functionalized by free-standing, accessible acylamide and hydroxyl units.
- Published
- 2015
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