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Background: Selenium (Se) is an essential micronutrient that performs physiological functions in the metabolism of thyroid hormone and may have an association with anthropometric variables relevant to cardiovascular disease. Aim: To study the associations between Se status, thyroid hormones and anthropometric variables in dyslipidemic patients. Methods: Eighty-three patients were assessed in a cross-sectional study. Blood samples were analyzed for Se and thyroid hormones. Anthropometric measurements were taken, and dietary Se intake was investigated. Results: Mean plasma Se concentrations were low in the patients, at 88.7 ± 16.7 μg/L. Patients with plasma Se ≥ 95 μg/L were found to have a higher body mass index (BMI) (30.74 �± 4.31 vs 27.68 �± 5.63 kg/m², P = 0.02) and waist-to-height ratio (0.65 �± 0.05 vs 0.59 �± 0.07, P = 0.003) when compared to those with concentrations between 80 and 94 μg/L. Se intake associated positively with T3L/T4L ratio (r = 0.273; P= 0.03), BMI (r= 0.257, P= 0.04) and WC (r= 0.299, P= 0.02). Conclusion: The patients with the highest normal plasma Se concentrations were found to have increases in the anthropometric variables we investigated. There is a need for further study in order to elucidate these findings. Furthermore, we found a positive association between Se intake and the most metabolically active form of the thyroid hormones. Contexto: El selenio (Se) es un micronutriente esencial que realiza las funciones fisiologicas en el metabolismo de la hormona tiroidea y pueden tener una asociacion con las variables antropometricas pertinentes a la enfermedad cardiovascular. Objetivo: Estudiar la asociacion entre el estado de Se, hormonas tiroideas y las variables antropometricas en pacientes con dislipidemia. Metodos: Ochenta y tres pacientes fueron evaluados en un estudio transversal. Se analizaron muestras de sangre para Se y hormonas tiroideas. Las medidas antropometricas fueron tomadas, y la ingesta de la dieta Se fue investigado. Resultados: La media de las concentraciones de Se en plasma fueron bajas en los pacientes, a 88,7 �± 16,7 mg / l. Se encontro que los pacientes con niveles plasmaticos de Se ≥ 95 mg / L de tener un indice de masa corporal (IMC) (30.74 �± 4.31 vs 27.68 �± 5.63 kg / m², P = 0,02) y la relacion cintura-estatura (0,65 ± 0,05 vs 0,59 �± 0,07, P = 0,003) en comparacion con aquellos con concentraciones entre 80 y 94 g / l. Ingesta de Se asocio positivamente con relacion T3L / T4L (r = 0,273, p = 0,03), indice de masa corporal (r = 0,257, P = 0,04) y WC (r = 0,299, P = 0,02). Conclusion: Se encontro que los pacientes con las mas altas concentraciones de Se en plasma normal tener incrementos en las variables antropometricas que investigamos. Hay una necesidad de un mayor estudio para dilucidar estos hallazgos. Ademas, se encontro una asociacion positiva entre el consumo de Se y la forma mas metabolicamente activa de las hormonas tiroideas.

Background: Selenium (Se) is an essential micronutrient that performs physiological functions in the metabolism of thyroid hormone and may have an association with anthropometric variables relevant to cardiovascular disease. Aim: To study the associations between Se status, thyroid hormones and anthropometric variables in dyslipidemic patients. Methods: Eighty-three patients were assessed in a cross-sectional study. Blood samples were analyzed for Se and thyroid hormones. Anthropometric measurements were taken, and dietary Se intake was investigated. Results: Mean plasma Se concentrations were low in the patients, at 88.7 ± 16.7 μg/L. Patients with plasma Se ≥ 95 μg/L were found to have a higher body mass index (BMI) (30.74 ± 4.31 vs 27.68 ± 5.63 kg/m², P = 0.02) and waist-to-height ratio (0.65 ± 0.05 vs 0.59 ± 0.07, P = 0.003) when compared to those with concentrations between 80 and 94 μg/L. Se intake associated positively with T3L/T4L ratio (r = 0.273; P= 0.03), BMI (r= 0.257, P= 0.04) and WC (r= 0.299, P= 0.02). Conclusion: The patients with the highest normal plasma Se concentrations were found to have increases in the anthropometric variables we investigated. There is a need for further study in order to elucidate these findings. Furthermore, we found a positive association between Se intake and the most metabolically active form of the thyroid hormones.