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Hypertension is a growing public health issue with serious health consequences worldwide. The association between nutritional factors and hypertension have been reported in the literature. This literature review aims to investigate the association between nutritional factors and hypertension. Studies published from 1999 to 2021 in English were search using Medline, Pubmed, Scopus, Web Science, and Google Scholar databases. Keywords included hypertension, blood pressure, fats, protein, carbohydrates, sodium, fiber, potassium, calcium, magnesium, diet and literature review. The number of references included in this review was 85. This review found a significant association between hypertension and consumption of saturated fats, monounsaturated and omega-3 fatty acids, sodium, potassium, fiber, and protein. However, there are still unclear and inconsistent associations in studies on the association between carbohydrates, calcium, and magnesium with hypertension.

Long An province, Vietnam, is one of the provinces in the Mekong Delta region, with the geographical location and natural conditions of dense rivers and canals, so it is easily affected by extreme weather phenomena, leading to impact on socio-economic issues in general and the field of traffic construction in particular. Especially, bridge works in the downstream area, in which the abutment and pier system is among the hardest impacted categories. This article uses the expert method by consulting experts and road managers in Long An province to identify the influencing factors. Then, the authors use SPSS20 software to build an econometric problem of regression analysis, assessing the influence of this factor on the management and exploitation of bridge abutments in the increasing conditions of climate change in Long An. After that, this study proposes solutions to minimize the impact of climate change on the bridge abutments in the Vam Co lower river, Long An province, Vietnam.

The central hypothesis of the genotype–phenotype relationship is that the phenotype of a developing organism (i.e., its set of observable attributes) depends on its genome and the environment. However, as we learn more about the genetics and biochemistry of living systems, our understanding does not fully extend to the complex multiscale nature of how cells move, interact, and organize; this gap in understanding is referred to as the genotype-to-phenotype problem. The physics of soft matter sets the background on which living organisms evolved, and the cell environment is a strong determinant of cell phenotype. This inevitably leads to challenges as the full function of many genes, and the diversity of cellular behaviors cannot be assessed without wide screens of environmental conditions. Cellular mechanobiology is an emerging field that provides methodologies to understand how cells integrate chemical and physical environmental stress and signals, and how they are transduced to control cell function. Biofilm forming bacteria represent an attractive model because they are fast growing, genetically malleable and can display sophisticated self-organizing developmental behaviors similar to those found in higher organisms. Here, we propose mechanobiology as a new area of study in prokaryotic systems and describe its potential for unveiling new links between an organism's genome and phenome.

Cell polarity is important for controlling cell shape, motility, and cell division processes. Vimentin intermediate filaments are necessary for proper polarization of migrating fibroblasts and assembly of vimentin and microtubule networks is dynamically coordinated, but the precise details of how vimentin mediates cell polarity remain unclear. Here, we characterize the effects of vimentin on the structure and microtubule-nucleating activity of the cell centrosome and the dynamics of the microtubule network in wild-type and vimentin-null mouse embryonic fibroblasts (mEF’s). We find that vimentin mediates the structure of the pericentrosomal material, promotes centrosomemediated microtubule regrowth, and increases the level of stable acetylated microtubules in the cell. Our results suggest that vimentin modulates centrosome structure and function as well as microtubule network stability, which has important implications for how cells establish proper cell polarization and persistent migration.

In Vietnam today, strengthening defense and security education for all classes of people, especially students at universities, is an essential job. In particular, one of the critical factors contributing to improving the quality of defense and security education for university students is the teaching staff of defense and security education. However, the teaching staff of defense and security education in Vietnamese universities needs more quantity and has certain limitations in quality. The article outlines several requirements posed to the teaching staff of national defense and security education and, on that basis, proposes some solutions to build the contingent of defense and security education lecturers in Vietnamese universities to meet the current development requirements of the country. Article visualizations

Vimentin intermediate filaments form part of the cytoskeleton of mesenchymal cells, but under pathological conditions often associated with inflammation, vimentin filaments depolymerize as the result of phosphorylation or citrullination, and vimentin oligomers are secreted or released into the extracellular environment. In the extracellular space, vimentin can bind surfaces of other cells and the extracellular matrix, and the interaction between extracellular vimentin and other cell types can trigger changes in cellular functions, such as activation of fibroblasts to a fibrotic phenotype. The mechanism by which extracellular vimentin binds external cell membranes and whether vimentin alone can act as an adhesive anchor for cells is largely uncharacterized. Here, we show that various cell types (normal and vimentin null fibroblasts, mesenchymal stem cells, A549 lung carcinoma cells) attach to and spread on polyacrylamide hydrogel substrates covalently linked to vimentin. Using traction force microscopy and spheroid expansion assays, we characterize how different cell types respond to extracellular vimentin. Cell attachment to and spreading on vimentin-coated surfaces is inhibited by hyaluronic acid (HA) degrading enzymes, HA synthase inhibitors, soluble heparin, or N-acetyl glucosamine, treatments that have little or no effect on the same cell types binding to collagen-coated hydrogels. These studies highlight the effectiveness of substrate-bound vimentin as a ligand for cells and suggest that carbohydrate structures, including the glycocalyx and glycosylated cell surface proteins that contain N-acetyl glucosamine, form a novel class of adhesion receptors for extracellular vimentin.

Sharing economy is a term that has been discussed a lot on e-commerce forums in Vietnam recently. This is a new business model that can bring super profits along with general benefits to society on the digital economy platform. The sharing economy is a new opportunity to change the way of doing business from owning assets to using assets without owning. In the past, the possession of physical-production materials or consumption materials was the most important factor in assessing the efficiency of enterprises or the quality of life, but the trend nowadays has changed. Throughout the industrial revolutions from the first to the fourth ones, the production force has had a remarkable development from mechanics, electrification, electronics, computers, artificial intelligence, and cloud computing... The influence of the fourth industrial revolution and the emergence of the sharing economy leads to the appearance of a new generation who prefer the consuming experience of possessing material. Along with that trend, the production relationship, including the ownership, also has certain changes such as the subjects and objects of the ownership, the new perception of ownership... Changes in ownership, when the sharing economy is formed and developed in Vietnam, has raised many problems such as changes in ownership objects in sharing economies require a complete institutional foundation of management; property rights, especially intellectual property; means and ways to evaluate and measure the efficiency and profitability of enterprises pursuing the form of "sharing economy". Henceforth, the article proposes several implications for solving problems that arise in ownership when developing the sharing economy in Vietnam, that is: completing the institution; providing a full and flexible legal environment; creating conditions for the effective development and management of subjects participating in the sharing economic model, consistent with the rapid change of science and technology platform; renewing the intellectual property regime in the direction of encouraging creativity and protecting property rights in all fields; building a system of means and methods for economic accounting and information transparency in the sharing economy; enhancing understanding of subjects when participating in the sharing economy; having a management mechanism to protect legal rights and interests as well as personal property.

O6-Methylguanine-DNA-methyltransferase (MGMT) promoter methylation was shown in many studies to be an important predictive biomarker for temozolomide (TMZ) resistance and poor progression-free survival in glioblastoma multiforme (GBM) patients. However, identifying the MGMT methylation status using molecular techniques remains challenging due to technical limitations, such as the inability to obtain tumor specimens, high prices for detection, and the high complexity of intralesional heterogeneity. To overcome these difficulties, we aimed to test the feasibility of using a novel radiomics-based machine learning (ML) model to preoperatively and noninvasively predict the MGMT methylation status. In this study, radiomics features extracted from multimodal images of GBM patients with annotated MGMT methylation status were downloaded from The Cancer Imaging Archive (TCIA) public database for retrospective analysis. The radiomics features extracted from multimodal images from magnetic resonance imaging (MRI) had undergone a two-stage feature selection method, including an eXtreme Gradient Boosting (XGBoost) feature selection model followed by a genetic algorithm (GA)-based wrapper model for extracting the most meaningful radiomics features for predictive purposes. The cross-validation results suggested that the GA-based wrapper model achieved the high performance with a sensitivity of 0.894, specificity of 0.966, and accuracy of 0.925 for predicting the MGMT methylation status in GBM. Application of the extracted GBM radiomics features on a low-grade glioma (LGG) dataset also achieved a sensitivity 0.780, specificity 0.620, and accuracy 0.750, indicating the potential of the selected radiomics features to be applied more widely on both low- and high-grade gliomas. The performance indicated that our model may potentially confer significant improvements in prognosis and treatment responses in GBM patients.

In 2016, the World Health Organization (WHO) updated the glioma classification by incorporating molecular biology parameters, including low-grade glioma (LGG). In the new scheme, LGGs have three molecular subtypes: isocitrate dehydrogenase (IDH)-mutated 1p/19q-codeleted, IDH-mutated 1p/19q-noncodeleted, and IDH-wild type 1p/19q-noncodeleted entities. This work proposes a model prediction of LGG molecular subtypes using magnetic resonance imaging (MRI). MR images were segmented and converted into radiomics features, thereby providing predictive information about the brain tumor classification. With 726 raw features obtained from the feature extraction procedure, we developed a hybrid machine learning-based radiomics by incorporating a genetic algorithm and eXtreme Gradient Boosting (XGBoost) classifier, to ascertain 12 optimal features for tumor classification. To resolve imbalanced data, the synthetic minority oversampling technique (SMOTE) was applied in our study. The XGBoost algorithm outperformed the other algorithms on the training dataset by an accuracy value of 0.885. We continued evaluating the XGBoost model, then achieved an overall accuracy of 0.6905 for the three-subtype classification of LGGs on an external validation dataset. Our model is among just a few to have resolved the three-subtype LGG classification challenge with high accuracy compared with previous studies performing similar work.

The field study was carried out in the grey degraded soil of Tri Ton town during Winter-Spring and Summer-Autumn crop of 2019- 2020. The field experiment was carried out by four treatments and four replications. Four treatments of Winter-Spring crop: The control treatment applied NPK (100 kgUrea + 556 kgP2O5 + 100kg KCl); (NT2): application of NPK, lime with Rhizobium inoculation; (NT3): NPK, cow manure and Rhizobium inoculation; (NT4):NPK, cow manure and lime with Rhizobium. Four treatments of Summer-Autumn cropwere carried on the prior experiment (Winter-Spring crop).However, treatments did not apply to cow manure, lime and Rhizobium(only NPK).The maximum plant biomass (168 g), number of nodule (92.1), fresh and dry weight of fill pods (61.4 and 37.6 g, respectively), fresh and dry weight of empty pods (2.07 and 1.19 g ), weight of dry nodules (0.83 g ) per plant, yield (6.12 ton ha-1), protein and oil in seeds (26.1 and 50.1%, respectively) were observed in cow manure and lime applied with Rhizobium inoculated treatments. All the parameters of growth and yield showed best result for application of lime and cow manure with synthetic Rhizobium inoculation of seeds. Cow manure has significantlyincreased the yield of peanut in the next crops. The results from our two crops of study showed that co-application of NPK, cow manure, lime and Rhizobium inoculation always increased field capacity in both crops.

It is important to provide high school students with the necessary information for them to consult and make a decision to choose a university. The study aims to identify and evaluate the influence of factors in the decision to choose a university for high school students. The questionnaire survey method was used to collect data from 393 students from eight high schools in An Giang Province, Vietnam. Exploratory factor analysis and linear regression were used to analyze the data. The research results show that students are quite satisfied and quite certain with their decision to choose a university, while there are six important factors affecting the decision to choose a university. Influential factors with decreasing order of magnitude are: i) Factors consulted by teachers, family, friends, and relatives; ii) Factors of future job opportunities; iii) Factors of media activities; iv) Factors of learning conditions; v) Factors of university reputation; vi) Factors belong to the students themselves. The findings of the study show that there is no statistically significant difference between the group of males and females, between grades 10, 11, and 12. Besides, there is a statistically significant difference between students in high schools. The findings of this study have theoretical and practical implications for university admissions in Vietnam. Proposals made to university administrators were discussed. From the research results, we want to help students find the right university, and support universities to improve the efficiency of admissions.

The ability of tissues to sustain and withstand mechanical stress is critical to tissue development and healthy tissue maintenance. The mechanical properties of tissues are typically considered to be dominated by the fibrous extracellular matrix (ECM) component of tissues. Fiber network mechanics can capture certain mechanical features of tissues, such as shear strain stiffening, but is insufficient in describing the compressive response of certain tissues and blood clots that are rich in extracellular matrix. To understand the mechanical response of tissues, we employ a contemporary mechanical model, a fibrous network of fibrin embedded with inert bead inclusions that preserve the volume-conserving constraints of cells in tissues. Combining bulk mechanical rheology and a custom imaging device, we show that the presence of inclusions alters the local dynamic remodeling of the networks undergoing uniaxial compressive strains and demonstrate non-affine correlated motion within a fiber-bead network, predicted to stretch fibers in the network and lead to the ability of the network to stiffen under compression, a key feature of real tissues. These findings have important implications for understanding how local structural properties of cells and ECM fibers impact the bulk mechanical response of real tissues. STATEMENT OF SIGNIFICANCE: To understand why real tissue stiffens under compression, we study a model tissue system which also stiffens: a fibrin network embedded with stiff beads. We design a device that images compression of both fiber and fiber-bead networks. Distinct from previous imaging studies, this setup can dynamically capture network deformation on scales larger than single fibers. From the videos, we see fluid flow and network remodeling are both critical to compression behavior. The fiber-bead network has faster fluid flow, reduced network recovery, and correlated motion during network relaxation. We hypothesize that the beads hinder network relaxation of stretched fibers, thus retaining the applied stress and exhibiting stiffening. Our findings reveal important details for modeling tissue mechanics towards optimizing healthcare.

Recollecting details from lifelog data involves a higher level of granularity and reasoning than a conventional lifelog retrieval task. Investigating the task of Question Answering (QA) in lifelog data could help in human memory recollection, as well as improve traditional lifelog retrieval systems. However, there has not yet been a standardised benchmark dataset for the lifelog-based QA. In order to provide a first dataset and baseline benchmark for QA on lifelog data, we present a novel dataset, LLQA, which is an augmented 85-day lifelog collection and includes over 15,000 multiple-choice questions. We also provide different baselines for the evaluation of future works. The results showed that lifelog QA is a challenging task that requires more exploration. The dataset is publicly available at https://github.com/allie-tran/LLQA.

The ability of bacteria to colonize and grow on different surfaces is an essential process for biofilm development. Here, we report the use of synthetic hydrogels with tunable stiffness and porosity to assess physical effects of the substrate on biofilm development. Using time-lapse microscopy to track the growth of expanding Serratia marcescens colonies, we find that biofilm colony growth can increase with increasing substrate stiffness, unlike what is found on traditional agar substrates. Using traction force microscopy-based techniques, we find that biofilms exert transient stresses correlated over length scales much larger than a single bacterium, and that the magnitude of these forces also increases with increasing substrate stiffness. Our results are consistent with a model of biofilm development in which the interplay between osmotic pressure arising from the biofilm and the poroelastic response of the underlying substrate controls biofilm growth and morphology.

Miniaturization and integration of optical tweezers are attractive. Optical fiber-based trapping systems allow optical traps to be realized in miniature systems, but the optical traps in these systems lack reliability or mobility. Here, we present the all-fiber modular optical tweezers (AFMOTs), in which an optical trap can be reliably created and freely moved on a sample substrate. Two inclined optical fibers are permanently fixed to a common board, rendering a modular system where fiber alignments are maintained over months. The freely movable optical trap allows particles to be trapped in their native locations. As a demonstration, we applied AFMOTs to trap and deform freely floating individual cells. By the cell mechanical responses, we differentiated the nontumorigenic breast epithelial cell line (MCF10A) from its cancerous PTEN mutants (MCF10 PTEN-/-). To further expand the functionalities, three modalities of AFMOTs are demonstrated by changing the types of fibers for both the optical trap creation and particle position detection. As a miniature and modular system that creates a reliable and mobile optical trap, AFMOTs can find potential applications ranging from point-of-care diagnostics to education, as well as helping transition the optical trapping technology from the research lab to the field.

This study explores and examines the factors that affect the composition of the quality relationship between manufacturers and distributors in the context of plastic industry in Vietnam. Qualitative research on single and group discussions with 23 manufacturers and distributors in the plastics industry. Quantitative research directly interviews 560 plastic product distributors in Ho Chi Minh City area and Southern provinces. The results of the study determine the composition of the relationship quality including three factors of trust, commitment and satisfaction; Six factors of product quality, delivery quality, market information, communication, personal interaction and visits affect the quality of the relationship between manufacturer and distributor.

The XIIIth National Congress of the Communist Party of Vietnam was held from January 25, 2021, to January 1, 2021, in Hanoi. The documents adopted at the Congress were built based on a profound summary of theory and practice; crystallizes the wisdom, will, and aspirations of the entire Party, people, and army. The article outlines the subject program and contents of the Resolution of the XIIIth Party Congress that need to be applied to teaching and researching the subject of national defense and security education at universities today. On that basis, proposing some issue that needs attention in the process of applying the Resolution of the XVIIIth Congress in teaching and research in the coming time.

In recent years, Vietnam has experienced urbanization and industrialization, leading to potential air pollution and climate change risks. To reduce these negative consequences of economic development, Vietnam has promoted a low-carbon economy (LCE) by setting many goals for green growth, air pollution reduction, and increasing the absorption capacity of greenhouse gases (GHGs) in many industrial sectors. However, there is still a lack of a specified policy to promote these goals systematically. This study proposes a set of criteria that could be used to evaluate and certify low-carbon industrial parks (LCIPs). The criteria were developed using Analytical Hierarchy Process (AHP), expert opinion, data normalization, and carbon emission calculation. The set of criteria includes five groups of indicators with eighteen criteria for evaluating LCIPs, which can be applied in Vietnam’s contexts. Using such an index system to Trang Bang IP in the period 2016–2020 as a case study, the results show that the Trang Bang has yet to meet the criteria of LCIPs, particularly in terms of energy consumption and GHGs emission.

For Λ the category of free opetopic algebras, we construct a model structure à la Cisinski on the category of presheaves over Λ, and show that is is equivalent to opetopic complete Segal spaces. This generalizes the results of Joyal and Tierney in the simplicial case, and of Cisinski and Moerdijk in the planar dendroidal case.

Opetopes are shapes (akin to globules, cubes, simplices, dendrices, etc.) introduced by Baez and Dolan to describe laws and coherence cells in higher-dimensional categories. In a nutshell, they are trees of trees of trees of trees of... These shapes are attractive because of their simple nature and easy to find ``in nature'', but their highly inductive definition makes them difficult to manipulate efficiently.This thesis develops the theory of opetopes along three main axes. First, we give it clean and robust foundations by carefully detailing the approach of Kock-Joyal-Batanin-Mascari, based on polynomial monads and trees. Starting with the identity functor on sets, and repeatedly applying the Baez-Dolan construction, we obtain a sequence of polynomial monads whose operations are trees over previous monads. This process generates opetopes and captures their recursive nature. We then introduce the important formalism of higher addresses, which allows to ``walk'' through opetopes and all their lower-dimensional faces simultaneously, in order to reach a given node or edge. This allows a more thorough investigation of the structure of the generating polynomial monads, and gives us important insights on the tree calculi they encode, in this case the natural operations on opetopes, such as grafting and substitution.The second part of this thesis deals with computerized manipulation of opetopes. We introduce two syntactical approaches to opetopes and opetopic sets. In each, opetopes are represented as syntactical constructs whose well-formation conditions are enforced by corresponding sequent calculi. In the first one, called the named approach, we express the compositional nature of opetopes using a specifically crafted kind of term. In the second, called unnamed approach, we just give a syntactical account of the tree structure of opetopes using higher addresses. This latter approach is closer to the definition of the first part of this thesis, whereas the former is more human-friendly.Lastly, in the third part of this thesis, we focus on the algebraic structures that can naturally be described by opetopes. So-called opetopic algebras include categories, planar operads, and Loday's combinads over planar trees. We start by extending the generating polynomial monads to categories of truncated opetopic sets, and let opetopic algebras be simply algebras over these extensions. Later, we introduce the category of opetopic shapes, and using the theory of parametric right adjoint monads of Weber, we show that opetopic algebras can also be understood as presheaves over opetopic shapes having the unique lifting property against a certain set of maps. We then turn our attention to the notion of weak opetopic algebras and their homotopy theory. Following the literature in the simplicial and dendroidal cases, we introduce three models: ∞-opetopic algebras, complete Segal spaces, and homotopy-coherent opetopic algebras. We show that classical results of Rezk, Joyal-Tierney, and Horel (for ∞-categories), and Cisinski-Moerdijk (for ∞-operads) can be reformulated and generalized in our setting. In particular, these models are equivalent., Les opétopes sont des formes (tout comme les globes, les cubes, les simplex, les dendrex, etc.) inventées par Baez et Dolan afin de pouvoir décrire les cellules de cohérence des catégories supérieures faibles. Informellement, ce sont des arbres d'arbres d'arbres d'arbres... Ces formes sont séduisantes car elles sont intrinsèquement simples et apparaissent fréquemment en pratique. Cependant, leur nature inductive les rend difficile à manipuler efficacement.Cette thèse développe la théorie des opétopes selon trois axes. Premièrement, nous formulons une définition propre et robuste, en suivant minutieusement l'approche de Kock-Joyal-Batanin-Mascari, basée sur la théorie des monades et des arbres polynomiaux. En itérant la construction de Baez-Dolan sur le foncteur identité sur la catégorie des ensembles, nous obtenons une suite de monades polynomiales, et leurs opérations sont des arbres sur des monades précédentes. Ce processus génère les opétopes et cerne leur structure récursive. Ensuite, nous présentons la notion d'adresse supérieure, qui nous permettent de « naviguer » dans les opétopes et leurs faces afin d'atteindre un noeud ou une arrête donné. Ce formalisme permet une étude plus poussée de la structure des monades polynomiales et des opérations sur les arbres qu'elles encapsulent. Dans notre cas, il s'agit des opérations naturelles sur les opétopes, par exemple les greffes et les substitutions.Ensuite, nous introduisons deux systèmes syntaxiques pour décrire les opétopes et les ensembles opétopiques, avec pour objectif leur implémentation informatique. Dans chacune de ces deux approches, les opétopes sont encodés par des expressions dont la validité est assurée par des calculs des séquents correspondants. Dans la première, appelée approche nommée, nous décrivons la structure compositionnelle des opétopes en utilisant un certain type de terme. La seconde, appelée approche anonyme, se concentre sur une représentation syntaxique simple des arbres sous jacents aux opétopes. Bien que plus proche de la définition polynomiale, sa syntaxe est moins facile à lire que celle de l'approche nommée.Enfin, dans la dernière partie de cette thèse, nous étudions les structures algébriques que les opétopes décrivent. Ces structures, que nous appelons algèbres opétopiques, généralisent les catégories, les opérades planaires, et les combinades des arbres planaires de Loday. Nous commençons pas étendre les monades génératrices à des catégories d'ensemble opétopiques tronqués, de sorte à ce que les algèbres opétopiques ne soient simplement que des algèbres sur ces extensions. Nous introduisons la catégories des formes opétopiques, et en mettant à contribution la théorie des adjoints à droite paramétriques de Weber, nous montrons que les algèbres opétopiques peuvent se comprendre comme des préfaisceaux satisfaisant certaines conditions de relèvement unique. Nous nous intéressons ensuite à la notion l'algèbre faible. En se basant sur les théories existantes dans le cas simplicial et dendroïdal, nous en donnons trois interprétations: les ∞-algèbres opétopiques, les espaces de Segal complets, et les algèbres opétopiques à homotopies cohérentes près. Nous montrons que certains résultats classiques de Rezk, Joyal-Tierney, et Horel (pour les ∞-catégories), et de Cisinski-Moerdijk (pour les ∞-opérades) peuvent être reformulés et généralisés dans ce cadre. En particulier, ces trois modèles sont équivalents.

Cultural belief is a unique feature that has an important value in the spiritual life of the Khmer people in the Mekong Delta. It is a bold combination of indigenous and religious colors, most of the Khmer in the Mekong Delta believe in Theravada Buddhists, taking it as one of their ways of life, as solid spiritual support to adjust behavior, and handling interpersonal, and social relationships. Cultural beliefs have created for the Khmer in the Mekong Delta to have a rich, unique spiritual life, bringing their own identity, contributing to diversity in the culture of Vietnam. This book highlights the manifestations of cultural belief and points out the values of cultural belief in the spiritual life of Khmer people in the Mekong Delta, and contributes to preserving, preserving the cultural belief of the Khmer people. Thereby, to preserve and promote cultural beliefs in the spiritual life of the Khmer people in the Mekong Delta in the sustainable development of the Khmer people in the Mekong Delta, Vietnam.

Purpose: Cranial magnetic resonance imaging (MRI) is recommended to identify intracranial lesions in girls with central precocious puberty (CPP). Yet, the use of routine MRI scans in girls with CPP is still debatable, as pathological findings in girls 6 years of age or older with CPP are limited. Therefore, we aimed to identify the prevalence of brain lessons in CPP patients stratified by age group (0–2, 2–6, and 6–8 years).Methods: This retrospective cross-sectional study recruited 257 girls diagnosed with CPP for 6 years (2010–2016). MRI was used to detect brain abnormalities. Levels of luteinizing hormone, follicle-stimulating hormone, and sex hormones in blood samples were measured.Results: Most girls had no brain lesions (82.9%, n=213), and of the minor proportion of girls with CPP that exhibited brain lesions (17.1%, n=44), 32 girls had organic CPP. Pathological findings were detected in 33.3% (2 of 6) of girls aged 0–2 years, 15.6% (5 of 32) of girls aged 2–6 years, and 3.6% (8 of 219) of girls aged 6–8 years. Hypothalamic hamartoma and tumors in the pituitary stalk were the most common pathological findings. The likelihood of brain lesions decreased with age. Girls with organic CPP were more likely to be younger (6.1±2.4 vs. 7.3±1.3 years, p

In the context that the fundamental and comprehensive reform of higher education in Vietnam is being promoted, it is becoming increasingly urgent to set requirements for innovation and to develop the team of lecturers, especially when the goal of education is the formation of personality and the development of personal capabilities for learners. With the identification of the teaching staff as the decisive factor for the success of the educational innovation process, the article summarizes and analyzes the current situation of the team of lecturers in higher education institutions in Vietnam today. On that basis, some basic solutions are proposed to develop the teaching staff to meet the tasks in the coming time. Article visualizations

Website quality of luxury hotels (from 4-star to 5-star ranking) is a vital role to attract customer’s first impression, satisfaction, engagement behaviors, and loyalty intentions. the study aims t...

Gold is a precious metal which is highly appreciated because of its prominent role in the world of investments, savings, and consumption. Although gold is no longer used as a primary form of currency in some countries, it continues to have a strong influence on the value of the currencies of those countries. Compared to all the other precious metals used for investment and trade, throughout history gold has always been preferred. The value of gold is a factor mentioned in the commodities and futures market. Vietnam does not produce/mine enough gold to meet its domestic requirements. As the country has to import over sixty percent of its gold, Vietnam's gold price is mostly influenced by the world price movements, in turn increasing or decreasing domestically. Therefore, understanding and addressing the factors resulting in gold price disparities is essential in policy adjustments to stabilize the price of gold and prevent speculation, which may cause economic destabilization as well as a loss of competitiveness in Vietnamese market for gold and other precious metals. The study includes monthly data collected between January 2006 and December 2015. Exchange rates, import tax, and seasonal factor data are included in the model as independent variables. According to the empirical findings, the foreign exchange rate had a negative impact on the disparity between Vietnamese gold price and the world price. The import tax has a positive effect on the discrepancies among gold prices, while the seasonal factor variable was not statistically significant at 5 percent and negative concerning the disparity of the gold price., Internal Grant Agency of FaME; TBU [IGA/FaME/2018/019]

This study focuses on the impact of empowering leadership and challenges work environment on both sale employee’s creativity and innovative work behavior in the Vietnamese banking industry. An empirical test, a structural equation model comprising a sample of 319 sale employees in 15 banks, indicates a strong relationship between sales staff creativity and innovative work behavior. Moreover, the findings indicate that both an empowering leadership and a challenging work environment can trigger sale employees’ creativity. Finally, innovative work behavior has a positive impact on innovative output. In general, this study contributes with some suggestions for bank managers to identify appropriate methods in order to stimulate the creativity and innovative work behavior of employees with the objective of achieving strong and sustainable business performance. © 2019, Sciendo. All rights reserved., Internal Grant Agency of FaME [IGA/FaME/2018/019]

One of the biggest environmental challenges of Vietnam is plastic wastes without recycling such as bottle, cans, plastic bag. The Vietnamese government have recognized these problems and called the reforming campaign to develop the sustainable technology to re-producing the wasted plastic. Thus, this research aims to contribute to deal with the issue by designing a plastic recycling machine. To satisfy domestic market of over 120 units at the first time, this research attempted to make a small machine at a low cost, but its throughput still reaches about 8kg plastic/hour and it can run within 16 consecutive hours a day. Hence, most of components is expected to be supplied by local vendors. As the result, the product price as well as maintenance cost is anticipated to be reduced. With the aim to produce the automated machine can incorporate continuous raw materials flow and at the same time move melted plastic in screw conveyor as defined by the regulation of the Programmable Logic Controllers (PLC) with timer to detect a velocity of melted plastic which come out from a nozzle of the screw conveyor and go to a mold. The hydraulic pressure, then, applies force to compressing and forming products. There are potential risks that can happen in fact, to deal with them. That is a reason Computer aid engineering and Finite element method modeling were conducted to make sure the force pressed in mold sufficiently and controlled the thickness of production as customer requirements.

The study aims to enhance the customer experience on hotel websites in the context of venue's booking channels to others. The online filed survey is conducted with 321 internet bookers. The exploratory factor analysis is adopted to analyze the data. The progression of customer satisfaction proceeds in a linear fashion on luxury (ranking from 4-star to 5-star hotels) websites. Moreover, the study reveals how hotel website performance would affect the levels of customer attitude and its sustainable development in the context of perceived e-service quality. The exploratory results show that customer satisfaction in online environment has identical processes in the context of up-scale hotel industry. The female group compared to male group, has more sensitive to perceive the impact of functionality of lodging website in developing customer satisfaction. Caution is advised in generalizing findings of this study due to stratified sampling even though the study confirms results of previously conducted studies. This study provides practical tips for website sustainable progress especially for hotel management to pay more attention to the e-service formation process. Therefore, the appropriate marketing strategy can be established to fill gender specific expectations towards individual degree of customer satisfaction., Internal Grant Agency of Faculty of Management and Economics, Tomas Bata University in Zlin [IGA/FaME/2018/009]

Saponin compounds released by Panax vietnamensis into the rhizosphere play critical roles in drug discovery. This study investigated the growth and saponin accumulation of P. vietnamensis adventitious root. Results showed the root growth and productivity of three-saponins (MR2, Rb1, and Rg1) were increased highest on the modified MS medium containing 7 mg/L IBA and 0.5 mg/L BA at 56 days. The root culture divided into three phases: (1) Growth phase 14–56 culture-days; (2) Stationary phase 56–70 days; and (3) Decline phase after 70 days. Saponin accumulation was significantly increased in the treatments of three plant-hormone-elicitors (JA, ABA, and SA), and two cell-wall elicitors (YE and CHN), but five elicitors inhibited formation lateral roots. Although contents of Rg1 (0.32%), Rb1 (0.85%), and MR2 (2.83%) were highest in JA treatment at 0.48 mM, 0.24 mM, and 0.96 mM JA respectively, maximum biomass as well as saponins productivity was observed in 150 mg/L YE. In addition, combination of YE and SA showed effective lower than the solitary YE treatment. The results suggest that adventitious root biomass of P. vietnamensis developed effectively in the modified MS medium after 56 days, and the culture could be scale-up in bioreactor 20 L.

Glioma is a Center Nervous System (CNS) neoplasm that arises from the glial cells. In a new scheme category of the World Health Organization 2016, lower-grade gliomas (LGGs) are grade II and III gliomas. Following the discovery of suppression of negative immune regulation, immunotherapy is a promising effective treatment method for lower-grade glioma patients. However, the therapy is not effective for all types of LGGs, and tumor mutational burden (TMB) has been shown to be a potential biomarker for the susceptibility and prognosis of immunotherapy in lower-grade glioma patients. Hence, predicting TMB benefits brain cancer patients. In this study, we investigated the correlation between MRI (magnetic resonance imaging)-based radiomic features and TMB in LGG by applying machine learning methods. Six machine learning classifiers were examined on the features extracted from the genetic algorithm. Subsequently, a light gradient boosting machine (LightGBM) succeeded in selecting 11 radiomics signatures for TMB classification. Our LightGBM model resulted in high accuracy of 0.7936, and reached a balance between sensitivity and specificity, achieving 0.76 and 0.8107, respectively. To our knowledge, our study represents the best model for classification of TMB in LGG patients at present.

Frenetic is a genetic approach that leverages a curvature-based road representation. Given an autonomous driving agent, the goal of Frenetic is to generate roads where the agent fails to stay within its lane. In other words, Frenetic tries to minimize the “out of bound distance”, which is the distance between the car and either edge of the lane if the car is within the lane, and proceeds to negative values once the car drives off. This work resembles classic aspects of genetic algorithms such as mutations and crossover, but introduces some nuances aiming at improving diversity of the generated roads.

The ability of cells to sense and respond to the mechanical stiffness of the surrounding matrix is important to support normal cell function, wound healing, and development. Central to the process of durosensing is the cytoskeleton composed of three classes of filaments: F-actin, microtubules, and intermediate filaments (IFs). Vimentin is an IF protein that contributes significantly to cell mechanics and cell traction force, which is required to probe extracellular matrix. The role of vimentin in how cells sense and respond to the mechanical rigidity of extracellular matrix is largely unclear. To investigate the role of vimentin in durosensing, we knocked down the vimentin expression level in 3T3 fibroblasts using shRNA transfection and measured cellular responses as functions of substrate stiffness. We quantified durosensitivity by the rates at which cell area and traction force change with substrate stiffness. Our results show that that vimentin plays a role in durosensing by modulating traction force and knocking out vimentin did not significantly affect durosensitivity. These results indicate that vimentin may be a redundant component of the machinery that cells use to sense substrate stiffness. This article is protected by copyright. All rights reserved.

In the development process of Japanese history, the Meiji period was of great significance. Thanks to the achievements of this reform, Japan can advance quickly on the path of industrialization and modernization and become the first capitalist power in Asia. The Meiji reform with its historical role and meaning has become an essential element in promoting the development of Japanese history in modern times. On the Asian level, the achievements of reform have much influence on regional countries. Many Asian countries have turned to the island nation and want to follow the development path of Japan. Over 150 years have passed, but the lessons learned from the Meiji reform are still valid, especially for Vietnam in the period of industrialization and modernization. The general article of Japan's Meiji reform (1868) is carried out in the fields of economy, politics, military, culture, and education. On that basis, give some useful lessons for Vietnam in the process of industrialization and modernization of the country today. Article visualizations

The use of rice straw for biochar production has been widely proved as a great alternative energy source, which not only is cheaper than other commercial coals but also helps mitigation of climate change. In this study, the rice straw–derived biochar was assessed as a sorption material used for livestock wastewater treatment, which has not much been studied so far. The biochar derived from rice straw had moisture content of 4.9 ± 0.5 %, bulk density of 0.38 ± 0.03 g/cm3, iodine number of 958.0 ± 37.0 mg/g, and pH was determined at 7.6 ± 0.1. The optimal contact time, biochar mass concentration, and pH were determined as 3.0 h, 4.0 g/L, and 9.0, respectively. The COD and BOD5 removal efficiencies were up to 40.0% via the batch experiment. However, the column test results showed the higher removal efficiencies which were 79.0 ± 6.1% for COD and 84.0 ± 2.5% for BOD5 with the influent COD concentration of 373.0 ± 8.0 mg/L and BOD5 concentration of 240.0 ± 3.0 mg/L. The effluent all met the current livestock wastewater discharge standard of Vietnam (QCVN 62-MT:2016/BTNMT). These findings indicate the potential of using straw-derived biochar as a good material for removing organic pollutants from livestock wastewater.