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2. Testicular transposition in children before scrotal external radiotherapy

Author

Nadège Corradini, Herve Lejeune, Stéphanie Bolle, Laurence Mengue, Frédéric Hameury, Line Claude, Marielle Le Bon, Laetitia Padovani, and Sylvie Helfre

Subjects
Male, endocrine system, medicine.medical_specialty, endocrine system diseases, Adolescent, media_common.quotation_subject, Fertility, Testicle, urologic and male genital diseases, External radiotherapy, Transposition (music), 03 medical and health sciences, 0302 clinical medicine, Testicular Neoplasms, Rare case, Testis, medicine, Humans, Young adult, Child, media_common, Retrospective Studies, urogenital system, business.industry, Cancer, Fertility Preservation, Hematology, medicine.disease, Prognosis, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, Child, Preschool, Pediatrics, Perinatology and Child Health, Scrotum, Radiology, Endocrine functions, business, Organ Sparing Treatments, 030215 immunology, Follow-Up Studies
Abstract

Testicular transposition (TT) before scrotal external radiotherapy (RT) is poorly reported in children with cancer, with only rare case reports published. TT surgical techniques, dosimetric parameters, and testicular functions are retrospectively reported in 12 children, median age 12.8 years, after scrotal RT for sarcomas. TT has low morbidity and allows a dramatic RT dose decrease in the healthy testicle. Endocrine functions seem preserved while more follow-up is needed to assess fertility. Though a rare situation, TT should be discussed in children and young adult cases when a scrotal high-dose RT is needed.

Published
2020

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