Search

Your search keyword '"Henderson, Gemma"' showing total 13 results
Start Over Author "Henderson, Gemma" Database OpenAIRE
13 results on '"Henderson, Gemma"'

1. Cultivation and sequencing of rumen microbiome members from the Hungate1000 Collection

Author

Seshadri, Rekha, Leahy, Sinead C, Attwood, Graeme T, Teh, Koon Hoong, Lambie, Suzanne C, Cookson, Adrian L, Eloe-Fadrosh, Emiley A, Pavlopoulos, Georgios A, Hadjithomas, Michalis, Varghese, Neha J, Paez-Espino, David, Hungate1000 project collaborators, Perry, Rechelle, Henderson, Gemma, Creevey, Christopher J, Terrapon, Nicolas, Lapebie, Pascal, Drula, Elodie, Lombard, Vincent, Rubin, Edward, Kyrpides, Nikos C, Henrissat, Bernard, Woyke, Tanja, Ivanova, Natalia N, and Kelly, William J

Subjects
animal structures, Rumen, Bacteria, Biofuels, Microbiota, Hungate1000 project collaborators, food and beverages, Animals, Humans, Archaea, Lignin, Gastrointestinal Microbiome
Abstract

Productivity of ruminant livestock depends on the rumen microbiota, which ferment indigestible plant polysaccharides into nutrients used for growth. Understanding the functions carried out by the rumen microbiota is important for reducing greenhouse gas production by ruminants and for developing biofuels from lignocellulose. We present 410 cultured bacteria and archaea, together with their reference genomes, representing every cultivated rumen-associated archaeal and bacterial family. We evaluate polysaccharide degradation, short-chain fatty acid production and methanogenesis pathways, and assign specific taxa to functions. A total of 336 organisms were present in available rumen metagenomic data sets, and 134 were present in human gut microbiome data sets. Comparison with the human microbiome revealed rumen-specific enrichment for genes encoding de novo synthesis of vitamin B12, ongoing evolution by gene loss and potential vertical inheritance of the rumen microbiome based on underrepresentation of markers of environmental stress. We estimate that our Hungate genome resource represents ∼75% of the genus-level bacterial and archaeal taxa present in the rumen.

Published
2018

2. Cultivation and sequencing of rumen microbiome members from the Hungate1000 Collection

Author

Seshadri, Rekha, Leahy, Sinead, Attwood, Graeme, Teh, Koon Hoong, Lambie, Suzanne, Cookson, Adrian, Eloe-Fadrosh, Emiley, Pavlopoulos, Georgios, Hadjithomas, Michalis, Varghese, Neha, Páez-Espino, David, Perry, Rechelle, Henderson, Gemma, Creevey, Christopher, Terrapon, Nicolas, Lapébie, Pascal, Drula, Elodie, Lombard, Vincent, Rubin, Edward, Kyrpides, Nikos, Henrissat, Bernard, Woyke, Tanja, Ivanova, Natalia, Kelly, William, Palevich, Nikola, Janssen, Peter, Ronimus, Ron, Noel, Samantha, Soni, Priya, Reilly, Kerri, Atherly, Todd, Ziemer, Cherie, Wright, Andre-Denis, Ishaq, Suzanne, Cotta, Michael, Thompson, Stephanie, Crosley, Katie, McKain, Nest, Wallace, R John, Flint, Harry, Martin, Jennifer, Forster, Robert, Gruninger, Robert, McAllister, Tim, Gilbert, Rosalind, Ouwerkerk, Diane, Klieve, Athol, Jassim, Rafat Al, Denman, Stuart, McSweeney, Chris, Rosewarne, Carly, Koike, Satoshi, Kobayashi, Yasuo, Mitsumori, Makoto, Shinkai, Takumi, Cravero, Silvio, Cucchi, María Cerón, Creevey, Chris, Seshadri, Rekha, Leahy, Sinead C, Attwood, Graeme T, Teh, Koon Hoong, Rosewarne, Carly, Cerón Cucchi, María, Hungate1000 Project Collaborators, US Department of Energy Joint Genome Institute, Walnut Creek CA, USA, DOE Joint Genome Institute [Walnut Creek], Grasslands Research Centre, AgResearch Ltd, AgResearch Limited, Grasslands Res Ctr, AgResearch, Department of Biology [JHU Baltimore], Johns Hopkins University (JHU), Animal & Grassland Research and Innovation Centre, Teagasc - The Agriculture and Food Development Authority (Teagasc), Aberystwyth University, Architecture et fonction des macromolécules biologiques (AFMB), Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Centre d'océanologie de Marseille (COM), Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Université de la Méditerranée - Aix-Marseille 2, Biodiversité et Biotechnologie Fongiques (BBF), École Centrale de Marseille (ECM)-Aix Marseille Université (AMU)-Institut National de la Recherche Agronomique (INRA), Department of Energy / Joint Genome Institute (DOE), Los Alamos National Laboratory (LANL), Rowett Inst Nutr & Hlth, Microbial Ecol Grp, University of Aberdeen, Laboratoire de Psycholinguistique Expérimentale (FAPSE), University of Geneva [Switzerland], Tohoku University [Sendai], Animal Bioscience Centre, European Project: 322820,EC:FP7:ERC,ERC-2012-ADG_20120314,HUMAN MICROBIOTA(2013), Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU)-Institut National de la Recherche Agronomique (INRA), Institut National de la Recherche Agronomique (INRA)-Aix Marseille Université (AMU)-École Centrale de Marseille (ECM), New Zealand Government - Livestock Research Group of the Global Research Alliance on Agricultural Greenhouse Gases, US Department of Energy Joint Genome Institute (JGI) through their Community Science Program [CSP 612, DE-AC02-05CH11231], Office of Science of the US Department of Energy, Leahy, Sinead C., Université de la Méditerranée - Aix-Marseille 2-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), and Université de Genève = University of Geneva (UNIGE)

Subjects
0301 basic medicine, BACTERIAL, Rumen, animal structures, Methanogenesis, DATABASE, Microbial metabolism, DIVERSITY, Biomedical Engineering, Bioengineering, Biology, Lignin, ANNOTATION, Applied Microbiology and Biotechnology, REFERENCE GENOMES, 03 medical and health sciences, Microbial ecology, [SDV.BBM.GTP]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Genomics [q-bio.GN], REVEALS, rumen microbiota, Animals, Humans, Microbiome, REDUCING EMISSIONS, 2. Zero hunger, Genetics, Bacteria, Microbiota, Human microbiome, food and beverages, biology.organism_classification, Archaea, EVOLUTION, Gastrointestinal Microbiome, 030104 developmental biology, Metagenomics, greenhouse gas, Biofuels, Molecular Medicine, RUMINANT NUTRITION, DAIRY-CATTLE, Biotechnology
Abstract

Hungate1000 project collaborators: Nikola Palevich, Peter H. Janssen, Ron S. Ronimus, Samantha Noel, Priya Soni, Kerri Reilly, Todd Atherly, Cherie Ziemer, Andre-Denis Wright, Suzanne Ishaq, Michael Cotta, Stephanie Thompson, Katie Crosley, Nest McKain, R. John Wallace, Harry J. Flint, Jennifer C. Martin, Robert J. Forster, Robert J. Gruninger, Tim McAllister, Rosalind Gilbert, Diane Ouwerkerk, Athol Klieve, Rafat Al Jassim, Stuart Denman, Chris McSweeney, Carly Rosewarne, Satoshi Koike, Yasuo Kobayashi, Makoto Mitsumori, Takumi Shinkai, Silvio Cravero & María Cerón Cucchi; International audience; Productivity of ruminant livestock depends on the rumen microbiota, which ferment indigestible plant polysaccharides into nutrients used for growth. Understanding the functions carried out by the rumen microbiota is important for reducing greenhouse gas production by ruminants and for developing biofuels from lignocellulose. We present 410 cultured bacteria and archaea, together with their reference genomes, representing every cultivated rumen-associated archaeal and bacterial family. We evaluate polysaccharide degradation, short-chain fatty acid production and methanogenesis pathways, and assign specific taxa to functions. A total of 336 organisms were present in available rumen metagenomic data sets, and 134 were present in human gut microbiome data sets. Comparison with the human microbiome revealed rumen-specific enrichment for genes encoding de novo synthesis of vitamin B12, ongoing evolution by gene loss and potential vertical inheritance of the rumen microbiome based on underrepresentation of markers of environmental stress. We estimate that our Hungate genome resource represents ∼75% of the genus-level bacterial and archaeal taxa present in the rumen.

Published
2018

3. Erratum: Rumen microbial community composition varies with diet and host, but a core microbiome is found across a wide geographical range

Author

Henderson, Gemma, Cox, Faith, Ganesh, Siva, Jonker, Arjan, Young, Wayne, Abecia, Leticia, Angarita, Erika, Aravena, Paula, Nora Arenas, Graciela, Ariza, Claudia, Attwood, Graeme T., Mauricio Avila, Jose, Avila-stagno, Jorge, Bannink, André, Barahona, Rolando, Batistotti, Mariano, Bertelsen, Mads F., Brown-Kav, Aya, Carvajal, Andres M., Cersosimo, Laura, Vieira Chaves, Alexandre, Church, John, Clipson, Nicholas, Cobos-peralta, Mario A., Cookson, Adrian L., Cravero, Silvio, Cristobal Carballo, Omar, Crosley, Katie, Cruz, Gustavo, Cerón Cucchi, María, de la Barra, Rodrigo, de Menezes, Alexandre B., Detmann, Edenio, Dieho, Kasper, Dijkstra, Jan, Dos Reis, William L.S., Dugan, Mike E.R., Hadi Ebrahimi, Seyed, Eythórsdóttir, Emma, Nde Fon, Fabian, Fraga, Martín, Franco, Francisco, Friedeman, Chris, Fukuma, Naoki, Gagić, Dragana, Gangnat, Isabelle, Javier Grilli, Diego, Guan, Le Luo, Heidarian Miri, Vahideh, Hernandez-Sanabria, Emma, Gomez, Alma Ximena Ibarra, Isah, Olubukola A., Ishaq, Suzanne, Jami, Elie, Jelincic, Juan, Kantanen, Juha, Kelly, William J., Kim, Seon-Ho, Klieve, Athol, Kobayashi, Yasuo, Koike, Satoshi, Kopecny, Jan, Nygaard Kristensen, Torsten, Julie Krizsan, Sophie, Lachance, Hannah, Lachman, Medora, Lamberson, William R., Lambie, Suzanne, Lassen, Jan, Leahy, Sinead C., Lee, Sang-Suk, Leiber, Florian, Lewis, Eva, Lin, Bo, Lira, Raúl, Lund, Peter, Macipe, Edgar, Mamuad, Lovelia L., Cuquetto Mantovani, Hilário, Marcoppido, Gisela Ariana, Márquez, Cristian, Martin, Cécile, Martinez, Gonzalo, Eugenia Martinez, Maria, Lucía Mayorga, Olga, McAllister, Tim A., McSweeney, Chris, Mestre, Lorena, Minnee, Elena, Mitsumori, Makoto, Mizrahi, Itzhak, Molina, Isabel, Muenger, Andreas, Muñoz, Camila, Murovec, Bostjan, Newbold, John, Nsereko, Victor, O’donovan, Michael, Okunade, Sunday, O’neill, Brendan, Ospina, Sonia, Ouwerkerk, Diane, Parra, Diana, Pereira, Luiz Gustavo Ribeiro, Pinares-patiño, Cesar, Pope, Phil B., Poulsen, Morten, Rodehutscord, Markus, Rodriguez, Tatiana, Saito, Kunihiko, Sales, Francisco, Sauer, Catherine, Shingfield, Kevin, Shoji, Noriaki, Simunek, Jiri, Stojanović-Radić, Zorica, Stres, Blaz, Sun, Xuezhao, Swartz, Jeffery, Liang Tan, Zhi, Tapio, Ilma, Taxis, Tasia M., Tomkins, Nigel, Ungerfeld, Emilio, Valizadeh, Reza, van Adrichem, Peter, van Hamme, Jonathan, van Hoven, Woulter, Waghorn, Garry, Wallace, John R., Wang, Min, Waters, Sinéad M., Keogh, Kate, Witzig, Maren, Wright, Andre-Denis G., Yamano, Hidehisa, Yan, Tianhai, Yáñez-ruiz, David R., Yeoman, Carl J., Zambrano, Ricardo, Zeitz, Johanna, Zhou, Mi, Wei Zhou, Hua, Xia Zou, Cai, Zunino, Pablo, and Janssen, Peter H.

Subjects
Multidisciplinary, Animal Nutrition, WIAS, Life Science, Laboratorium voor Plantenfysiologie, Diervoeding, Laboratory of Plant Physiology
Abstract

Ruminant livestock are important sources of human food and global greenhouse gas emissions. Feed degradation and methane formation by ruminants rely on metabolic interactions between rumen microbes and affect ruminant productivity. Rumen and camelid foregut microbial community composition was determined in 742 samples from 32 animal species and 35 countries, to estimate if this was influenced by diet, host species, or geography. Similar bacteria and archaea dominated in nearly all samples, while protozoal communities were more variable. The dominant bacteria are poorly characterised, but the methanogenic archaea are better known and highly conserved across the world. This universality and limited diversity could make it possible to mitigate methane emissions by developing strategies that target the few dominant methanogens. Differences in microbial community compositions were predominantly attributable to diet, with the host being less influential. There were few strong co-occurrence patterns between microbes, suggesting that major metabolic interactions are non-selective rather than specific.

Published
2016

8. The Changing Face of Domestic Abuse Service Provision

Author

Henderson, Gemma

Subjects
education, humanities, health care economics and organizations
Abstract

This article aims to explore the changing reality of domestic abuse service provision to victims of domestic abuse in the South West of England. By interviewing the professionals who work with the victims, it explores how cuts to funding is altering provisions for victims and multi-agency working and the realities of the move to tendering via the commissioning process. Results illustrate that austerity measures and government reforms have negatively affected domestic abuse service provision over recent years. Not only are there fewer services available but also changes in social policy are forcing the specialist domestic abuse charities to be replaced by large, generic organisations.

Published
2016

12. Phylogeny of human intestinal bacteria that activate the dietary lignan secoisolariciresinol diglucoside

Author

Clavel, Thomas, Henderson, Gemma, Engst, Wolfram, Doré, Joël, Blaut, Michael, Unité de recherche d'Écologie et Physiologie du Système Digestif (UEPSD), Institut National de la Recherche Agronomique (INRA), Department of Gastrointestinal Microbiology, German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE), Department of Nutritional Toxicology, and German Institute of Human Nutrition

Subjects
[SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, PHYLOGENY, INTESTINAL MICROBIOTA, GLUCOSIDE, ENTEROLACTONE
Abstract

International audience; The human intestinal microbiota is essential for the conversion of the dietary lignan secoisolariciresinol diglucoside (SDG) via secoisolariciresinol (SECO) to the enterolignans enterodiol (ED) and enterolactone (EL). However, knowledge of the species that catalyse the underlying reactions is scant. Therefore, we focused our attention on the identification of intestinal bacteria involved in the conversion of SDG. Strains of Bacteroides distasonis, Bacteroides fragilis, Bacteroides ovatus and Clostridium cocleatum, as well as the newly isolated strain Clostridium sp. SDG-Mt85-3Db, deglycosylated SDG. Demethylation of SECO was catalysed by strains of Butyribacterium methylotrophicum, Eubacterium callanderi, Eubacterium limosum and Peptostreptococcus productus. Dehydroxylation of SECO was catalysed by strains of Clostridium scindens and Eggerthella lenta. Finally, the newly isolated strain ED-Mt61/PYG-s6 catalysed the dehydrogenation of ED to EL. The results indicate that the activation of SDG involves phylogenetically diverse bacteria, most of which are members of the dominant human intestinal microbiota.

Published
2006

13. Rumen microbial community composition varies with diet and host, but a core microbiome is found across a wide geographical range

Author

Henderson, Gemma, Cox, Faith, Ganesh, Siva, Jonker, Arjan, Young, Wayne, Global Rumen Census Collaborators, and Janssen, Peter H.

Subjects
2. Zero hunger, animal structures, 13. Climate action, 15. Life on land
Abstract

Ruminant livestock are important sources of human food and global greenhouse gas emissions. Feed degradation and methane formation by ruminants rely on metabolic interactions between rumen microbes and affect ruminant productivity. Rumen and camelid foregut microbial community composition was determined in 742 samples from 32 animal species and 35 countries, to estimate if this was influenced by diet, host species, or geography. Similar bacteria and archaea dominated in nearly all samples, while protozoal communities were more variable. The dominant bacteria are poorly characterised, but the methanogenic archaea are better known and highly conserved across the world. This universality and limited diversity could make it possible to mitigate methane emissions by developing strategies that target the few dominant methanogens. Differences in microbial community compositions were predominantly attributable to diet, with the host being less influential. There were few strong co-occurrence patterns between microbes, suggesting that major metabolic interactions are non-selective rather than specific., Scientific Reports, 5, ISSN:2045-2322

Catalog

Books, media, physical & digital resources
See catalog results