1. Clustered cases of infections due to an uncommon methicillin-resistant Staphylococcus aureus originating in a maternity ward
- Author
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P. Martins-Simões, Pierre-Yves Donnio, L.A. King, H. Isly, K. Le Neindre, A. Tristan, Guillaume Menard, G. Auger, A. Morin-Le Bihan, ARN régulateurs bactériens et médecine (BRM), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), CHU Pontchaillou [Rennes], Santé publique France - French National Public Health Agency [Saint-Maurice, France], Hospices Civils de Lyon, Departement de Neurologie (HCL), Institut des Agents Infectieux [Lyon] (IAI), Hospices Civils de Lyon (HCL), This work did not receive any grant from funding agencies in the public, commercial, or not-for-profit sectors., Jonchère, Laurent, and Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )
- Subjects
Methicillin-Resistant Staphylococcus aureus ,medicine.medical_specialty ,media_common.quotation_subject ,[SDV]Life Sciences [q-bio] ,MRSA ,medicine.disease_cause ,community-acquired infections ,Phenotypic analysis ,Hygiene ,Pregnancy ,[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,Internal medicine ,Epidemiology ,medicine ,Humans ,media_common ,outbreak ,Transmission (medicine) ,business.industry ,Public health ,Soft Tissue Infections ,Infant, Newborn ,Outbreak ,Staphylococcal Infections ,maternity ,Methicillin-resistant Staphylococcus aureus ,Hospitals ,3. Good health ,[SDV] Life Sciences [q-bio] ,Infectious Diseases ,Staphylococcus aureus ,[SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases ,Female ,Panton-Valentin leukocidin ,business - Abstract
International audience; OBJECTIVE: We aimed to report a community outbreak of an uncommon methicillin-resistant Staphylococcus aureus (MRSA) originating in a maternity ward. PATIENTS AND METHODS: Cases were defined by epidemiological, clinical, and microbiological investigations. Microbiological investigations included phenotypic analysis, molecular typing, and whole genome sequencing. To control the outbreak, we applied both national recommendations to prevent in-hospital transmission and the French High Council for Public Health guidelines on the management of community-acquired MRSA infections. RESULTS: Between March and July 2016, seven patients with MRSA infections were identified: six skin and soft tissue infections and one pulmonary infection, including six microbiologically confirmed infections. Infections occurred in community settings, but a link with the same maternity ward was found for all patients. All MRSA strains had a t690 spa type, were tetracycline-resistant, and produced Panton-Valentine leukocidin. All isolates belonged to the sequence type 88 (ST88). CONCLUSION: This outbreak highlights the largely underestimated risk of healthcare-associated infections in maternity wards. Healthcare workers should be aware of the importance of standard hygiene precautions and use of alcohol-based hand sanitizers for neonates and mothers.
- Published
- 2021
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