1. Demystifying the varying case fatality rates (CFR) of COVID-19 in India: Lessons learned and future directions
- Author
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Melvin Joy, Jeyaseelan Lakshmanan, Charishma Jones Sarman, and Edwin Sam Asirvatham
- Subjects
COVID-19 ,Case Fatality Rate ,CFR ,predictors ,fractional regression ,Coronavirus disease 2019 (COVID-19) ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Pneumonia, Viral ,030231 tropical medicine ,Population ,India ,Comorbidity ,Microbiology ,Betacoronavirus ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Virology ,Case fatality rate ,Pandemic ,Humans ,Medicine ,030212 general & internal medicine ,education ,Pandemics ,Estimation ,education.field_of_study ,SARS-CoV-2 ,business.industry ,General Medicine ,Targeted interventions ,medicine.disease ,Infectious Diseases ,Data Interpretation, Statistical ,Parasitology ,Coronavirus Infections ,business ,Demography - Abstract
Introduction: At the end of the second week of June 2020, the SARS-CoV-2 responsible for COVID-19 infected above 7.5 million people and killed over 400,000 worldwide. Estimation of case fatality rate (CFR) and determining the associated factors are critical for developing targeted interventions. Methodology: The state-level adjusted case fatality rate (aCFR) was estimated by dividing the cumulative number of deaths on a given day by the cumulative number confirmed cases 8 days before, which is the average time-lag between diagnosis and death. We conducted fractional regression analysis to determine the predictors of aCFR. Results: As of 13 June 2020, India reported 225 COVID-19 cases per million population (95% CI:224-226); 6.48 deaths per million population (95% CI:6.34-6.61) and an aCFR of 3.88% (95% CI:3.81-3.97) with wide variation between states. High proportion of urban population and population above 60 years were significantly associated with increased aCFR (p=0.08, p=0.05), whereas, high literacy rate and high proportion of women were associated with reduced aCFR (p
- Published
- 2020
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