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The test develops the theme of prevention from degradation and maintenance archaeological area of the Roman Villa of Terme Vigliatore, situated in the territory of Messina and protected under cover designed by Franco Minissi. The cover, similar to that achieved by Minissi for the Villa Romana del Casale of Piazza Armerina, ensured the conservation of an archaeological site that has a considerable scientific interest in the studies concerning the mosaics of the period late ancient in Sicily and the Mediterranean. However, the archaeological site of Terme Vigliatore pays, today, in a state of insecurity restorative, invaded by the vegetation that grows uncontrolled, and by an absence of maintenance, too long of the archaeological evidence and of the system of coverage.

Although substantial progress has been made in the therapeutic options currently available for patients with advanced non-small cell lung cancer (NSCLC), the overall survival profile remains poor for most patients. One of the strategies currently under investigation with the aim of prolonging survival in NSCLC patients is maintenance treatment with either a chemotherapeutic agent or a molecularly targeted agent after first-line chemotherapy. Moreover, this can consist of drugs included in the induction regimen or other noncrossresistant agents. With the currently available data, maintenance treatment with a different noncrossresistant agent (i.e., an early second-line treatment) is perhaps the most promising strategy. The drug chosen for the early second-line treatment should be a well-tolerated agent, considering that patients have just completed a particularly toxic platinum-based chemotherapy. Extending treatment with targeted agents rather than chemotherapy can provide longer progression-free and overall survival times without increasing toxicity. However, at the moment, only progression-free survival has been shown to be consistently superior with maintenance approaches; the evaluation of survival benefits is warranted before defining this strategy as a possible treatment option. Further studies are warranted to establish the role of maintenance chemotherapy in patients with advanced NSCLC.