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1. MR Restricted Diffusion in Anterior Ischemic Optic Neuropathy in Giant Cell Arteritis

Author: Pasquale F. Finelli and Amre H. Nouh
Subjects: Ophthalmology, Neurology (clinical)
Published: 2023

2. New Onset Focal Tremor in Patient With Human Immunodeficiency Virus

Author: Pasquale F Finelli
Subjects: Microbiology (medical), Infectious Diseases, Tremor, Humans, HIV, HIV Infections
Published: 2022

3. MR Three-Territory Sign in Cancer-Associated Hypercoagulation Stroke (Trousseau Syndrome)

Author: Pasquale F. Finelli
Subjects: Male, medicine.medical_specialty, Neurology, medicine.diagnostic_test, business.industry, Cancer, Magnetic resonance imaging, medicine.disease, Malignancy, Magnetic Resonance Imaging, Occult, Stroke, Diffusion Magnetic Resonance Imaging, Neoplasms, medicine, Etiology, Humans, Thrombophilia, Adenocarcinoma, Female, Radiology, business, Aged
Abstract: Background Stroke in the setting of three-territory lesion pattern on magnetic resonance-diffusion-weighted imaging "three-territory sign" (TTS) is predominately due to cancer-associated hypercoagulation (CAH). Our goal is to determine the frequency with which "TTS" is overlooked as a diagnostic feature of cancer-associated hypercoagulation stroke. Methods Over a 4-year period (October 2016 to October 2020), stroke admissions with magnetic resonance imaging defined three-territory diffusion-weighted imaging lesions were identified. Patients were prospectively accrued in an observational study from the neurology service at Hartford Hospital, a 938 bed facility with a comprehensive stroke center with 2792 stroke admissions during the study period. Results Twenty-two patients met selection criteria, 4 due to infectious endocarditis, 16 due to stroke from CAH and 2 with no identifiable etiology. Of the 16 CAH patients, 5 were male and 11 female, mean age=72 (range: 47 to 91). Cancer type (biopsy proven unless noted) was cholangiocarcinoma=3, adenocarcinoma of lung=3, adenocarcinoma of breast=1, pancreatic carcinoma=3 (2 biopsy, 1 ultrasound), adenocarcinoma, origin unknown=1, non-small cell carcinoma of lung=2, carcinoid=1, ovarian carcinoma=1, lung mass (not biopsied)=1. Malignancy was known in 7 and occult in 9 at stroke presentation. Consideration of malignancy-related hypercoagulation as the cause of stroke was appreciated in 1 of 16 radiology reports and in 4 of 16 neurology admission notes. Conclusion TTS is a frequently missed diagnostic magnetic resonance feature in cancer-associated hypercoagulation stroke and often heralds occult malignancy.
Published: 2021

4. Impact of Soft Errors on High Performance Autoencoders for Cyberattack Detection

Author: F. Finelli, M. Omana, and C. Metra
Published: 2022

5. Biopsy negative giant cell arteritis-Revised diagnostic criteria: Giant cell arteritis diagnostic criteria

Author: Pasquale F. Finelli
Subjects: Biopsy, Rehabilitation, Giant Cell Arteritis, Humans, Surgery, Neurology (clinical), Cardiology and Cardiovascular Medicine, Temporal Arteries
Abstract: Diagnosis of giant cell arteritis has traditionally relied on demonstration of pathologic changes on temporal artery biopsy.To highlight recent advances in large vessel imaging resulting in revised diagnostic criteria for giant cell arteritis.We call attention to the revised diagnostic criteria imaging evidence of extracranial large vessel thickening as an alternative to temporal artery biopsy in diagnosis of giant cell arteritis in a patient with heralding anterior fornix infarct.
Published: 2022

6. Constraints on Primordial Magnetic Fields from their impact on the ionization history with Planck 2018

Author: D Paoletti, J Chluba, F Finelli, and J A Rubiño-Martín
Subjects: Cosmology and Nongalactic Astrophysics (astro-ph.CO), Space and Planetary Science, FOS: Physical sciences, Astronomy and Astrophysics, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: We update and extend our previous CMB anisotropy constraints on primordial magnetic fields through their dissipation by ambipolar diffusion and MHD decaying turbulence effects on the post-recombination ionization history. We derive the constraints using the latest Planck 2018 data release which improves on the E-mode polarization leading to overall tighter constraints with respect to Planck 2015. We also use the low-multipole E-mode polarization likelihood obtained by the SROLL2 map making algorithm and we note how it is compatible with larger magnetic field amplitudes than the Planck 2018 baseline, especially for positive spectral indices. The 95% CL constraints on the amplitude of the magnetic fields from the combination of the effects is $\sqrt{\langle B^2 \rangle}, 11 pages, 11 figures
Published: 2022

7. Erratum: Energy-momentum tensor and helicity for gauge fields coupled to a pseudoscalar inflaton [Phys. Rev. D 100 , 123542 (2019)]

Author: M. Ballardini, M. Braglia, F. Finelli, G. Marozzi, and A. A. Starobinsky
Published: 2022

8. MR Target Sign in Cerebral Aspergillosis

Author: Pasquale F. Finelli
Subjects: medicine.medical_specialty, medicine.diagnostic_test, business.industry, Magnetic resonance imaging, 030218 nuclear medicine & medical imaging, Brain disease, 03 medical and health sciences, 0302 clinical medicine, Short Reports, Feature (computer vision), Cerebral aspergillosis, medicine, Effective diffusion coefficient, Neurology (clinical), Radiology, business, Modality (semiotics), 030217 neurology & neurosurgery
Abstract: Magnetic resonance (MR) is an effective imaging modality in the evaluation of infectious brain disease, yet findings are often nonspecific. The presence of a diagnostic feature can facilitate early treatment, particularly where mortality is high. We highlight MR apparent diffusion coefficient/T2-weighted target sign in the diagnosis of cerebral aspergillosis.
Published: 2020

9. Optical Characterization of OMT-Coupled TES Bolometers for LiteBIRD

Author: J. Hubmayr, P. A. R. Ade, A. Adler, E. Allys, D. Alonso, K. Arnold, D. Auguste, J. Aumont, R. Aurlien, J. E. Austermann, S. Azzoni, C. Baccigalupi, A. J. Banday, R. Banerji, R. B. Barreiro, N. Bartolo, S. Basak, E. Battistelli, L. Bautista, J. A. Beall, D. Beck, S. Beckman, K. Benabed, J. Bermejo-Ballesteros, M. Bersanelli, J. Bonis, J. Borrill, F. Bouchet, F. Boulanger, S. Bounissou, M. Brilenkov, M. L. Brown, M. Bucher, E. Calabrese, M. Calvo, P. Campeti, A. Carones, F. J. Casas, A. Catalano, A. Challinor, V. Chan, K. Cheung, Y. Chinone, C. Chiocchetta, S. E. Clark, L. Clermont, S. Clesse, J. Cliche, F. Columbro, J. A. Connors, A. Coppolecchia, W. Coulton, J. Cubas, A. Cukierman, D. Curtis, F. Cuttaia, G. D’Alessandro, K. Dachlythra, P. de Bernardis, T. de Haan, E. de la Hoz, M. De Petris, S. Della Torre, J. J. Daz Garca, C. Dickinson, P. Diego-Palazuelos, M. Dobbs, T. Dotani, D. Douillet, E. Doumayrou, L. Duband, A. Ducout, S. M. Duff, J. M. Duval, K. Ebisawa, T. Elleflot, H. K. Eriksen, J. Errard, T. Essinger-Hileman, S. Farrens, F. Finelli, R. Flauger, K. Fleury-Frenette, C. Franceschet, U. Fuskeland, L. Galli, S. Galli, M. Galloway, K. Ganga, J. R. Gao, R. T. Genova-Santos, M. Georges, M. Gerbino, M. Gervasi, T. Ghigna, S. Giardiello, E. Gjerlw, R. Gonzlez Gonzles, M. L. Gradziel, J. Grain, L. Grandsire, F. Grupp, A. Gruppuso, J. E. Gudmundsson, N. W. Halverson, J. Hamilton, P. Hargrave, T. Hasebe, M. Hasegawa, M. Hattori, M. Hazumi, S. Henrot-Versill, B. Hensley, D. Herman, D. Herranz, G. C. Hilton, E. Hivon, R. A. Hlozek, D. Hoang, A. L. Hornsby, Y. Hoshino, K. Ichiki, T. Iida, T. Ikemoto, H. Imada, K. Ishimura, H. Ishino, G. Jaehnig, M. Jones, T. Kaga, S. Kashima, N. Katayama, A. Kato, T. Kawasaki, R. Keskitalo, C. Kintziger, T. Kisner, Y. Kobayashi, N. Kogiso, A. Kogut, K. Kohri, E. Komatsu, K. Komatsu, K. Konishi, N. Krachmalnicoff, I. Kreykenbohm, C. L. Kuo, A. Kushino, L. Lamagna, J. V. Lanen, G. Laquaniello, M. Lattanzi, A. T. Lee, C. Leloup, F. Levrier, E. Linder, M. J. Link, A. I. Lonappan, T. Louis, G. Luzzi, J. Macias-Perez, T. Maciaszek, B. Maffei, D. Maino, M. Maki, S. Mandelli, M. Maris, B. Marquet, E. Martnez-Gonzlez, F. A. Martire, S. Masi, M. Massa, M. Masuzawa, S. Matarrese, F. T. Matsuda, T. Matsumura, L. Mele, A. Mennella, M. Migliaccio, Y. Minami, K. Mitsuda, A. Moggi, M. Monelli, A. Monfardini, J. Montgomery, L. Montier, G. Morgante, B. Mot, Y. Murata, J. A. Murphy, M. Nagai, Y. Nagano, T. Nagasaki, R. Nagata, S. Nakamura, R. Nakano, T. Namikawa, F. Nati, P. Natoli, S. Nerval, N. Neto Godry Farias, T. Nishibori, H. Nishino, F. Noviello, G. C. O’Neil, C. O’Sullivan, K. Odagiri, H. Ochi, H. Ogawa, S. Oguri, H. Ohsaki, I. S. Ohta, N. Okada, L. Pagano, A. Paiella, D. Paoletti, G. Pascual Cisneros, A. Passerini, G. Patanchon, V. Pelgrim, J. Peloton, V. Pettorino, F. Piacentini, M. Piat, G. Piccirilli, F. Pinsard, G. Pisano, J. Plesseria, G. Polenta, D. Poletti, T. Prouv, G. Puglisi, D. Rambaud, C. Raum, S. Realini, M. Reinecke, C. D. Reintsema, M. Remazeilles, A. Ritacco, P. Rosier, G. Roudil, J. Rubino-Martin, M. Russell, H. Sakurai, Y. Sakurai, M. Sandri, M. Sasaki, G. Savini, D. Scott, J. Seibert, Y. Sekimoto, B. Sherwin, K. Shinozaki, M. Shiraishi, P. Shirron, A. Shitvov, G. Signorelli, G. Smecher, F. Spinella, J. Starck, S. Stever, R. Stompor, R. Sudiwala, S. Sugiyama, R. Sullivan, A. Suzuki, J. Suzuki, T. Suzuki, T. L. Svalheim, E. Switzer, R. Takaku, H. Takakura, S. Takakura, Y. Takase, Y. Takeda, A. Tartari, D. Tavagnacco, A. Taylor, E. Taylor, Y. Terao, L. Terenzi, J. Thermeau, H. Thommesen, K. L. Thompson, B. Thorne, T. Toda, M. Tomasi, M. Tominaga, N. Trappe, M. Tristram, M. Tsuji, M. Tsujimoto, C. Tucker, R. Ueki, J. N. Ullom, K. Umemori, L. Vacher, J. Van Lanen, G. Vermeulen, P. Vielva, F. Villa, M. R. Vissers, N. Vittorio, B. Wandelt, W. Wang, I. K. Wehus, J. Weller, B. Westbrook, G. Weymann-Despres, J. Wilms, B. Winter, E. J. Wollack, N. Y. Yamasaki, T. Yoshida, J. Yumoto, K. Watanuki, A. Zacchei, M. Zannoni, A. Zonca, Hubmayr, J, Ade, P, Adler, A, Allys, E, Alonso, D, Arnold, K, Auguste, D, Aumont, J, Aurlien, R, Austermann, J, Azzoni, S, Baccigalupi, C, Banday, A, Banerji, R, Barreiro, R, Bartolo, N, Basak, S, Battistelli, E, Bautista, L, Beall, J, Beck, D, Beckman, S, Benabed, K, Bermejo-Ballesteros, J, Bersanelli, M, Bonis, J, Borrill, J, Bouchet, F, Boulanger, F, Bounissou, S, Brilenkov, M, Brown, M, Bucher, M, Calabrese, E, Calvo, M, Campeti, P, Carones, A, Casas, F, Catalano, A, Challinor, A, Chan, V, Cheung, K, Chinone, Y, Chiocchetta, C, Clark, S, Clermont, L, Clesse, S, Cliche, J, Columbro, F, Connors, J, Coppolecchia, A, Coulton, W, Cubas, J, Cukierman, A, Curtis, D, Cuttaia, F, D’Alessandro, G, Dachlythra, K, de Bernardis, P, de Haan, T, de la Hoz, E, De Petris, M, Della Torre, S, Daz Garca, J, Dickinson, C, Diego-Palazuelos, P, Dobbs, M, Dotani, T, Douillet, D, Doumayrou, E, Duband, L, Ducout, A, Duff, S, Duval, J, Ebisawa, K, Elleflot, T, Eriksen, H, Errard, J, Essinger-Hileman, T, Farrens, S, Finelli, F, Flauger, R, Fleury-Frenette, K, Franceschet, C, Fuskeland, U, Galli, L, Galli, S, Galloway, M, Ganga, K, Gao, J, Genova-Santos, R, Georges, M, Gerbino, M, Gervasi, M, Ghigna, T, Giardiello, S, Gjerlw, E, Gonzles, R, Gradziel, M, Grain, J, Grandsire, L, Grupp, F, Gruppuso, A, Gudmundsson, J, Halverson, N, Hamilton, J, Hargrave, P, Hasebe, T, Hasegawa, M, Hattori, M, Hazumi, M, Henrot-Versill, S, Hensley, B, Herman, D, Herranz, D, Hilton, G, Hivon, E, Hlozek, R, Hoang, D, Hornsby, A, Hoshino, Y, Ichiki, K, Iida, T, Ikemoto, T, Imada, H, Ishimura, K, Ishino, H, Jaehnig, G, Jones, M, Kaga, T, Kashima, S, Katayama, N, Kato, A, Kawasaki, T, Keskitalo, R, Kintziger, C, Kisner, T, Kobayashi, Y, Kogiso, N, Kogut, A, Kohri, K, Komatsu, E, Komatsu, K, Konishi, K, Krachmalnicoff, N, Kreykenbohm, I, Kuo, C, Kushino, A, Lamagna, L, Lanen, J, Laquaniello, G, Lattanzi, M, Lee, A, Leloup, C, Levrier, F, Linder, E, Link, M, Lonappan, A, Louis, T, Luzzi, G, Macias-Perez, J, Maciaszek, T, Maffei, B, Maino, D, Maki, M, Mandelli, S, Maris, M, Marquet, B, Martnez-Gonzlez, E, Martire, F, Masi, S, Massa, M, Masuzawa, M, Matarrese, S, Matsuda, F, Matsumura, T, Mele, L, Mennella, A, Migliaccio, M, Minami, Y, Mitsuda, K, Moggi, A, Monelli, M, Monfardini, A, Montgomery, J, Montier, L, Morgante, G, Mot, B, Murata, Y, Murphy, J, Nagai, M, Nagano, Y, Nagasaki, T, Nagata, R, Nakamura, S, Nakano, R, Namikawa, T, Nati, F, Natoli, P, Nerval, S, Neto Godry Farias, N, Nishibori, T, Nishino, H, Noviello, F, O’Neil, G, O’Sullivan, C, Odagiri, K, Ochi, H, Ogawa, H, Oguri, S, Ohsaki, H, Ohta, I, Okada, N, Pagano, L, Paiella, A, Paoletti, D, Pascual Cisneros, G, Passerini, A, Patanchon, G, Pelgrim, V, Peloton, J, Pettorino, V, Piacentini, F, Piat, M, Piccirilli, G, Pinsard, F, Pisano, G, Plesseria, J, Polenta, G, Poletti, D, Prouv, T, Puglisi, G, Rambaud, D, Raum, C, Realini, S, Reinecke, M, Reintsema, C, Remazeilles, M, Ritacco, A, Rosier, P, Roudil, G, Rubino-Martin, J, Russell, M, Sakurai, H, Sakurai, Y, Sandri, M, Sasaki, M, Savini, G, Scott, D, Seibert, J, Sekimoto, Y, Sherwin, B, Shinozaki, K, Shiraishi, M, Shirron, P, Shitvov, A, Signorelli, G, Smecher, G, Spinella, F, Starck, J, Stever, S, Stompor, R, Sudiwala, R, Sugiyama, S, Sullivan, R, Suzuki, A, Suzuki, J, Suzuki, T, Svalheim, T, Switzer, E, Takaku, R, Takakura, H, Takakura, S, Takase, Y, Takeda, Y, Tartari, A, Tavagnacco, D, Taylor, A, Taylor, E, Terao, Y, Terenzi, L, Thermeau, J, Thommesen, H, Thompson, K, Thorne, B, Toda, T, Tomasi, M, Tominaga, M, Trappe, N, Tristram, M, Tsuji, M, Tsujimoto, M, Tucker, C, Ueki, R, Ullom, J, Umemori, K, Vacher, L, Van Lanen, J, Vermeulen, G, Vielva, P, Villa, F, Vissers, M, Vittorio, N, Wandelt, B, Wang, W, Wehus, I, Weller, J, Westbrook, B, Weymann-Despres, G, Wilms, J, Winter, B, Wollack, E, Yamasaki, N, Yoshida, T, Yumoto, J, Watanuki, K, Zacchei, A, Zannoni, M, Zonca, A, and National Aeronautics and Space Administration (US)
Subjects: CMB, TES, OMT, Low temperature detector, Bolometer, FIS/05 - ASTRONOMIA E ASTROFISICA, Settore FIS/05 - Astronomia e Astrofisica, General Materials Science, Condensed Matter Physics, CMB, TES, OMT, Low temperature detector, Bolometer, Atomic and Molecular Physics, and Optics
Abstract: et al., Feedhorn- and orthomode transducer- (OMT) coupled transition edge sensor (TES) bolometers have been designed and micro-fabricated to meet the optical specifications of the LiteBIRD high frequency telescope (HFT) focal plane. We discuss the design and optical characterization of two LiteBIRD HFT detector types: dual-polarization, dual-frequency-band pixels with 195/280 GHz and 235/337 GHz band centers. Results show well-matched passbands between orthogonal polarization channels and frequency centers within 3% of the design values. The optical efficiency of each frequency channel is conservatively reported to be within the range 0.64−0.72, determined from the response to a cryogenic, temperature-controlled thermal source. These values are in good agreement with expectations and either exceed or are within 10% of the values used in the LiteBIRD sensitivity forecast. Lastly, we report a measurement of loss in Nb/SiNx/Nb microstrip at 100 mK and over the frequency range 200–350 GHz, which is comparable to values previously reported in the literature., This work is supported by NASA under grant no. 80NSSC18K0132.
Published: 2022

10. Reply to Koster et al. letter to editor

Author: Pasquale F. Finelli
Subjects: Rehabilitation, Surgery, Neurology (clinical), Cardiology and Cardiovascular Medicine
Published: 2022

11. Three Territory Sign

Author: Ilene Staff, Pasquale F. Finelli, and Amre Nouh
Subjects: medicine.medical_specialty, business.industry, Research, Radiography, Atrial fibrillation, 030204 cardiovascular system & hematology, Malignancy, medicine.disease, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Ischemic stroke, Cohort, Cardiology, medicine, Etiology, In patient, cardiovascular diseases, Neurology (clinical), business, Stroke, 030217 neurology & neurosurgery
Abstract: BackgroundMultiple acute cerebral territory infarcts of undetermined origin are typically attributed to cardioembolism, most frequently atrial fibrillation. However, the importance of 3-territory involvement in association with malignancy is under-recognized. We sought to highlight the “Three Territory Sign” (TTS) (bilateral anterior and posterior circulation acute ischemic diffusion-weighted imaging [DWI] lesions), as a radiographic marker of stroke due to malignancy.MethodsWe conducted a single-center retrospective analysis of patients from January 2014 to January 2016, who suffered an acute ischemic stroke with MRI-DWI at our institution, yielding 64 patients with a known malignancy and 167 patients with atrial fibrillation, excluding patients with both to eliminate bias. All DWI images were reviewed for 3-, 2-, and 1-territory lesions. Chi-square test of proportion was used to test significance between the 2 groups.ResultsWe found an association between the groups (malignancy vs atrial fibrillation) and the number of territory infarcts (p < 0.0001). Pairwise comparisons using the Holm p value adjustment showed no difference between 1- and 2-territory patterns (p = 0.465). However, the TTS was 6 times more likely observed within the malignancy cohort as compared to patients with atrial fibrillation (23.4% [n = 15] vs 3.5% [n = 6]) and was different from both 1-territory (p < 0.0001) and 2-territory patterns (p = 0.0032).ConclusionThe TTS is a highly specific marker and 6 times more frequently observed in malignancy-related ischemic stroke than atrial fibrillation-related ischemic stroke. Evaluation for underlying malignancy in patients with the TTS is reasonable in patients with undetermined etiology.
Published: 2019

12. Bridging hybrid- and full-kinetic models with Landau-fluid electrons

Author: F. Finelli, S. S. Cerri, F. Califano, F. Pucci, D. Laveder, G. Lapenta, T. Passot
Published: 2021
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13. Updated design of the CMB polarization experiment satellite LiteBIRD

Author: H. Sugai, P. A. R. Ade, Y. Akiba, D. Alonso, K. Arnold, J. Aumont, J. Austermann, C. Baccigalupi, A. J. Banday, R. Banerji, R. B. Barreiro, S. Basak, J. Beall, S. Beckman, M. Bersanelli, J. Borrill, F. Boulanger, M. L. Brown, M. Bucher, A. Buzzelli, E. Calabrese, F. J. Casas, A. Challinor, V. Chan, Y. Chinone, J.-F. Cliche, F. Columbro, A. Cukierman, D. Curtis, P. Danto, P. de Bernardis, T. de Haan, M. De Petris, C. Dickinson, M. Dobbs, T. Dotani, L. Duband, A. Ducout, S. Duff, A. Duivenvoorden, J.-M. Duval, K. Ebisawa, T. Elleflot, H. Enokida, H. K. Eriksen, J. Errard, T. Essinger-Hileman, F. Finelli, R. Flauger, C. Franceschet, U. Fuskeland, K. Ganga, J.-R. Gao, R. Génova-Santos, T. Ghigna, A. Gomez, M. L. Gradziel, J. Grain, F. Grupp, A. Gruppuso, J. E. Gudmundsson, N. W. Halverson, P. Hargrave, T. Hasebe, M. Hasegawa, M. Hattori, M. Hazumi, S. Henrot-Versille, D. Herranz, C. Hill, G. Hilton, Y. Hirota, E. Hivon, R. Hlozek, D.-T. Hoang, J. Hubmayr, K. Ichiki, T. Iida, H. Imada, K. Ishimura, H. Ishino, G. C. Jaehnig, M. Jones, T. Kaga, S. Kashima, Y. Kataoka, N. Katayama, T. Kawasaki, R. Keskitalo, A. Kibayashi, T. Kikuchi, K. Kimura, T. Kisner, Y. Kobayashi, N. Kogiso, A. Kogut, K. Kohri, E. Komatsu, K. Komatsu, K. Konishi, N. Krachmalnicoff, C. L. Kuo, N. Kurinsky, A. Kushino, M. Kuwata-Gonokami, L. Lamagna, M. Lattanzi, A. T. Lee, E. Linder, B. Maffei, D. Maino, M. Maki, A. Mangilli, E. Martínez-González, S. Masi, R. Mathon, T. Matsumura, A. Mennella, M. Migliaccio, Y. Minami, K. Mistuda, D. Molinari, L. Montier, G. Morgante, B. Mot, Y. Murata, J. A. Murphy, M. Nagai, R. Nagata, S. Nakamura, T. Namikawa, P. Natoli, S. Nerval, T. Nishibori, H. Nishino, Y. Nomura, F. Noviello, C. O’Sullivan, H. Ochi, H. Ogawa, H. Ohsaki, I. Ohta, N. Okada, L. Pagano, A. Paiella, D. Paoletti, G. Patanchon, F. Piacentini, G. Pisano, G. Polenta, D. Poletti, T. Prouvé, G. Puglisi, D. Rambaud, C. Raum, S. Realini, M. Remazeilles, G. Roudil, J. A. Rubiño-Martín, M. Russell, H. Sakurai, Y. Sakurai, M. Sandri, G. Savini, D. Scott, Y. Sekimoto, B. D. Sherwin, K. Shinozaki, M. Shiraishi, P. Shirron, G. Signorelli, G. Smecher, P. Spizzi, S. L. Stever, R. Stompor, S. Sugiyama, A. Suzuki, J. Suzuki, E. Switzer, R. Takaku, H. Takakura, S. Takakura, Y. Takeda, A. Taylor, E. Taylor, Y. Terao, K. L. Thompson, B. Thorne, M. Tomasi, H. Tomida, N. Trappe, M. Tristram, M. Tsuji, M. Tsujimoto, C. Tucker, J. Ullom, S. Uozumi, S. Utsunomiya, J. Van Lanen, G. Vermeulen, P. Vielva, F. Villa, M. Vissers, N. Vittorio, F. Voisin, I. Walker, N. Watanabe, I. Wehus, J. Weller, B. Westbrook, B. Winter, E. Wollack, R. Yamamoto, N. Y. Yamasaki, M. Yanagisawa, T. Yoshida, J. Yumoto, M. Zannoni, A. Zonca, Sugai, H, Ade, P, Akiba, Y, Alonso, D, Arnold, K, Aumont, J, Austermann, J, Baccigalupi, C, Banday, A, Banerji, R, Barreiro, R, Basak, S, Beall, J, Beckman, S, Bersanelli, M, Borrill, J, Boulanger, F, Brown, M, Bucher, M, Buzzelli, A, Calabrese, E, Casas, F, Challinor, A, Chan, V, Chinone, Y, Cliche, J, Columbro, F, Cukierman, A, Curtis, D, Danto, P, de Bernardis, P, de Haan, T, De Petris, M, Dickinson, C, Dobbs, M, Dotani, T, Duband, L, Ducout, A, Duff, S, Duivenvoorden, A, Duval, J, Ebisawa, K, Elleflot, T, Enokida, H, Eriksen, H, Errard, J, Essinger-Hileman, T, Finelli, F, Flauger, R, Franceschet, C, Fuskeland, U, Ganga, K, Gao, J, Génova-Santos, R, Ghigna, T, Gomez, A, Gradziel, M, Grain, J, Grupp, F, Gruppuso, A, Gudmundsson, J, Halverson, N, Hargrave, P, Hasebe, T, Hasegawa, M, Hattori, M, Hazumi, M, Henrot-Versille, S, Herranz, D, Hill, C, Hilton, G, Hirota, Y, Hivon, E, Hlozek, R, Hoang, D, Hubmayr, J, Ichiki, K, Iida, T, Imada, H, Ishimura, K, Ishino, H, Jaehnig, G, Jones, M, Kaga, T, Kashima, S, Kataoka, Y, Katayama, N, Kawasaki, T, Keskitalo, R, Kibayashi, A, Kikuchi, T, Kimura, K, Kisner, T, Kobayashi, Y, Kogiso, N, Kogut, A, Kohri, K, Komatsu, E, Komatsu, K, Konishi, K, Krachmalnicoff, N, Kuo, C, Kurinsky, N, Kushino, A, Kuwata-Gonokami, M, Lamagna, L, Lattanzi, M, Lee, A, Linder, E, Maffei, B, Maino, D, Maki, M, Mangilli, A, Martínez-González, E, Masi, S, Mathon, R, Matsumura, T, Mennella, A, Migliaccio, M, Minami, Y, Mistuda, K, Molinari, D, Montier, L, Morgante, G, Mot, B, Murata, Y, Murphy, J, Nagai, M, Nagata, R, Nakamura, S, Namikawa, T, Natoli, P, Nerval, S, Nishibori, T, Nishino, H, Nomura, Y, Noviello, F, O’Sullivan, C, Ochi, H, Ogawa, H, Ohsaki, H, Ohta, I, Okada, N, Pagano, L, Paiella, A, Paoletti, D, Patanchon, G, Piacentini, F, Pisano, G, Polenta, G, Poletti, D, Prouvé, T, Puglisi, G, Rambaud, D, Raum, C, Realini, S, Remazeilles, M, Roudil, G, Rubiño-Martín, J, Russell, M, Sakurai, H, Sakurai, Y, Sandri, M, Savini, G, Scott, D, Sekimoto, Y, Sherwin, B, Shinozaki, K, Shiraishi, M, Shirron, P, Signorelli, G, Smecher, G, Spizzi, P, Stever, S, Stompor, R, Sugiyama, S, Suzuki, A, Suzuki, J, Switzer, E, Takaku, R, Takakura, H, Takakura, S, Takeda, Y, Taylor, A, Taylor, E, Terao, Y, Thompson, K, Thorne, B, Tomasi, M, Tomida, H, Trappe, N, Tristram, M, Tsuji, M, Tsujimoto, M, Tucker, C, Ullom, J, Uozumi, S, Utsunomiya, S, Van Lanen, J, Vermeulen, G, Vielva, P, Villa, F, Vissers, M, Vittorio, N, Voisin, F, Walker, I, Watanabe, N, Wehus, I, Weller, J, Westbrook, B, Winter, B, Wollack, E, Yamamoto, R, Yamasaki, N, Yanagisawa, M, Yoshida, T, Yumoto, J, Zannoni, M, Zonca, A, World Premier International Research Center (Japan), Japan Society for the Promotion of Science, Ministry of Education, Culture, Sports, Science and Technology (Japan), Agenzia Spaziale Italiana, Istituto Nazionale di Fisica Nucleare, Centre National D'Etudes Spatiales (France), Centre National de la Recherche Scientifique (France), Commissariat à l'Ènergie Atomique et aux Ènergies Alternatives (France), European Space Agency, Canadian Space Agency, National Aeronautics and Space Administration (US), Institut de recherche en astrophysique et planétologie (IRAP), Institut national des sciences de l'Univers (INSU - CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Observatoire Midi-Pyrénées (OMP), Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Centre National de la Recherche Scientifique (CNRS), Institut d'astrophysique spatiale (IAS), Université Paris-Sud - Paris 11 (UP11)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Centre National d’Études Spatiales [Paris] (CNES), Commissariat à l'énergie atomique et aux énergies alternatives - Laboratoire d'Electronique et de Technologie de l'Information (CEA-LETI), Direction de Recherche Technologique (CEA) (DRT (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Laboratoire de l'Accélérateur Linéaire (LAL), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), Institut d'Astrophysique de Paris (IAP), Institut national des sciences de l'Univers (INSU - CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Institut Néel (NEEL), Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud - Paris 11 (UP11)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Centre National d’Études Spatiales [Paris] (CNES), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Hélium : du fondamental aux applications (NEEL - HELFA), Université Grenoble Alpes (UGA)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Sugai, H. [0000-0001-6501-3871], and Apollo - University of Cambridge Repository
Subjects: Passive cooling, Cosmic Microwave Background, Cosmology, Polarimetry, Instrumentation, Inflation, Cosmic microwave background, cosmic background radiation: polarization, 7. Clean energy, 01 natural sciences, Polarization, General Materials Science, 010303 astronomy & astrophysics, media_common, Physics, Settore FIS/01, Settore FIS/05, Astrophysics::Instrumentation and Methods for Astrophysics, suppression, Condensed Matter Physics, Polarization (waves), Atomic and Molecular Physics, and Optics, Infation, adiabatic, Astrophysics - Instrumentation and Methods for Astrophysics, signature, Astrophysics and Astronomy, media_common.quotation_subject, Lagrangian point, Inflation, Primordial gravitational wave, Satellite, FOS: Physical sciences, Astrophysics::Cosmology and Extragalactic Astrophysics, Noise (electronics), Article, NO, FIS/05 - ASTRONOMIA E ASTROFISICA, Settore FIS/05 - Astronomia e Astrofisica, 0103 physical sciences, noise: thermal, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Instrumentation and Methods for Astrophysics (astro-ph.IM), 010308 nuclear & particles physics, Gravitational wave, PE9_14, beam: width, gravitational radiation: primordial, Astronomy, 13. Climate action, Sky, spectral, galaxy, astro-ph.IM
Abstract: H. Sugai, et al., Recent developments of transition-edge sensors (TESs), based on extensive experience in ground-based experiments, have been making the sensor techniques mature enough for their application on future satellite cosmic microwave background (CMB) polarization experiments. LiteBIRD is in the most advanced phase among such future satellites, targeting its launch in Japanese Fiscal Year 2027 (2027FY) with JAXA’s H3 rocket. It will accommodate more than 4000 TESs in focal planes of reflective low-frequency and refractive medium-and-high-frequency telescopes in order to detect a signature imprinted on the CMB by the primordial gravitational waves predicted in cosmic inflation. The total wide frequency coverage between 34 and 448 GHz enables us to extract such weak spiral polarization patterns through the precise subtraction of our Galaxy’s foreground emission by using spectral differences among CMB and foreground signals. Telescopes are cooled down to 5 K for suppressing thermal noise and contain polarization modulators with transmissive half-wave plates at individual apertures for separating sky polarization signals from artificial polarization and for mitigating from instrumental 1/f noise. Passive cooling by using V-grooves supports active cooling with mechanical coolers as well as adiabatic demagnetization refrigerators. Sky observations from the second Sun–Earth Lagrangian point, L2, are planned for 3 years. An international collaboration between Japan, the USA, Canada, and Europe is sharing various roles. In May 2019, the Institute of Space and Astronautical Science, JAXA, selected LiteBIRD as the strategic large mission No. 2., This work was supported by World Premier International Research Center Initiative (WPI), MEXT, Japan, by JSPS Core-to-Core Program, A. Advanced Research Networks, and by JSPS KAKENHI Grant Numbers JP15H05891, JP17H01115, and JP17H01125. The Italian contribution to the LiteBIRD phase A is supported by the Italian Space Agency (ASI Grant No. 2016-24- H.1-2018) and the National Institute for Nuclear Physics (INFN). The French contribution to the LiteBIRD phase A is supported by the Centre National d’Etudes Spatiale (CNES), by the Centre National de la Recherche Scientifque (CNRS), and by the Commissariat à l’Energie Atomique (CEA). A Concurrent Design Facility study focused on the MHFT and Sub-Kelvin coolers has been led by the European Space Agency (ESA). The Canadian contribution to LiteBIRD is supported by the Canadian Space Agency. The US contribution is supported by NASA Grant no. 80NSSC18K0132
Published: 2020
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14. Optic Nerve Enhancement and Restricted Diffusion in Postoperative Visual Loss

Author: Pasquale F. Finelli
Subjects: medicine.medical_specialty, MRI diffusion, genetic structures, business.industry, medicine.disease, Mr imaging, eye diseases, Photo Essay, 03 medical and health sciences, Ophthalmology, Aortic aneurysm, 0302 clinical medicine, Feature (computer vision), Restricted Diffusion, 030221 ophthalmology & optometry, medicine, Optic nerve, Posterior ischemic optic neuropathy, sense organs, Neurology (clinical), Radiology, business, 030217 neurology & neurosurgery
Abstract: Postoperative visual loss is rare and most often due to posterior ischemic optic neuropathy. We describe optic nerve MR imaging of a 37-year-old man with postoperative visual loss due to posterior ischemic optic neuropathy after complicated aortic aneurysm surgery. MR demonstrated restricted diffusion and focal enhancement of both optic nerves. Combined restricted diffusion and focal enhancement is a unique MR imaging feature with postoperative vision loss.
Published: 2018

15. A Fatal Case of Undiagnosed Candida Meningitis

Author: Pasquale F. Finelli
Subjects: Male, Fungal meningitis, medicine.medical_specialty, MEDLINE, Autopsy, Diagnostic system, 03 medical and health sciences, Fatal Outcome, 0302 clinical medicine, Chronic meningitis, Health care, Humans, Medicine, Diagnosis, Computer-Assisted, 030212 general & internal medicine, Diagnostic Errors, Intensive care medicine, Candida, Intravenous drug, business.industry, General Medicine, Middle Aged, medicine.disease, Meningitis, Fungal, Neurology (clinical), business, Meningitis, 030217 neurology & neurosurgery
Abstract: Diagnostic error is an increasing health care concern. An intravenous drug abuser with chronic meningitis died after a prolonged hospitalization from fungal meningitis diagnosed at autopsy. We examine the diagnostic pitfalls and consider how a computer-assisted diagnostic system may influence the outcome of an otherwise fatal condition.
Published: 2018

16. Diagnostic approach to restricted-diffusion patterns on MR imaging

Author: Pasquale F. Finelli
Subjects: Text mining, business.industry, Feature (computer vision), Restricted Diffusion, Association (object-oriented programming), Etiology, MEDLINE, Medicine, Neurology (clinical), Disease, business, Bioinformatics, Mr imaging
Abstract: The vast majority of restricted-diffusion abnormalities result from acute stroke, and as such, the diagnosis may be problematic when this MRI feature results from other causes. Distinct patterns of restricted diffusion seen with various disease conditions can play an important diagnostic role. The association of certain diseases with a given restricted-diffusion pattern allows for a focused assessment to determine a specific etiology.
Published: 2018

17. Abstract WMP72: The 'Three Territory Sign': An Under-Recognized Radiographic Marker of Malignancy-Related Ischemic Stroke

Author: Ilene Staff, Pasquale F. Finelli, and Amre Nouh
Subjects: Advanced and Specialized Nursing, medicine.medical_specialty, medicine.diagnostic_test, business.industry, Radiography, Magnetic resonance imaging, Atrial fibrillation, medicine.disease, Malignancy, Internal medicine, Ischemic stroke, medicine, Cardiology, cardiovascular diseases, Neurology (clinical), Cardiology and Cardiovascular Medicine, business, Stroke, Sign (mathematics)
Abstract: Background: Multiple cerebral territory infarcts of undetermined origin are typically attributed to cardioembolism; and most frequently atrial fibrillation. However the significance of three territory involvement in association with malignancy is under-recognized. Objective: To highlight the “Three Territory Sign” (bilateral anterior and the posterior circulation DWI lesions), as a radiographic marker of stroke due to malignancy. Methods: We conducted a retrospective analysis of patients at our institution from Jan 2014-Jan 2016 who suffered an acute ischemic stroke with MRI-DWI. We identified all ischemic strokes of undetermined etiology in patients with known malignancy (60 patients) and patients with stroke, atrial fibrillation and no malignancy (167 patients). Patients with both atrial fibrillation and malignancy were excluded. All DWI images were reviewed for 3, 2, and 1 territory lesions. Fisher Exact tests were used to identify statistical significance between the two groups. Statistical significance was set at 0.05. Results: There was a significant association between both cohorts (malignancy vs. atrial fibrillation) and the number of territory infarcts found. While the number of 1 {71.6% (n=43) vs. 79% (n=132)} and 2 territory infarcts {10.0% (n=6) vs. 17. 4% (n=29)} were similar between the two groups, 3 territory infarcts were > 5 times more frequent in malignancy as compared to atrial fibrillation {18.3% (n=11) vs. 3.5% (n=6)} ( p < 0.002 ). Post-hoc pairwise comparisons using the Bonferroni correction for multiple tests support that the 3 territory pattern differs from both 1 territory ( p=0.0033 ) and 2 territory ( p =0.0037 ) patterns. Conclusion: Cerebral territory infarctions involving the bilateral anterior and posterior circulation are 5 times more frequent in malignancy-related ischemic stroke than atrial fibrillation. The “Three territory sign” is a robust marker of malignancy-related stroke and should prompt evaluation for malignancy after exclusion of other known causes.
Published: 2018

18. Exploring cosmic origins with CORE: Inflation

Author: F. Finelli, M. Bucher, A. Achúcarro, M. Ballardini, N. Bartolo, D. Baumann, S. Clesse, J. Errard, W. Handley, M. Hindmarsh, K. Kiiveri, M. Kunz, A. Lasenby, M. Liguori, D. Paoletti, C. Ringeval, J. Väliviita, B. van Tent, V. Vennin, P. Ade, R. Allison, F. Arroja, M. Ashdown, A.J. Banday, R. Banerji, J.G. Bartlett, S. Basak, P. de Bernardis, M. Bersanelli, A. Bonaldi, J. Borril, F.R. Bouchet, F. Boulanger, T. Brinckmann, C. Burigana, A. Buzzelli, Z.-Y. Cai, M. Calvo, C.S. Carvalho, G. Castellano, A. Challinor, J. Chluba, I. Colantoni, A. Coppolecchia, M. Crook, G. D'Alessandro, G. D'Amico, J. Delabrouille, V. Desjacques, G. De Zotti, J.M. Diego, E. Di Valentino, S. Feeney, J.R. Fergusson, R. Fernandez-Cobos, S. Ferraro, F. Forastieri, S. Galli, J. García-Bellido, G. de Gasperis, R.T. Génova-Santos, M. Gerbino, J. González-Nuevo, S. Grandis, J. Greenslade, S. Hagstotz, S. Hanany, D.K. Hazra, C. Hernández-Monteagudo, C. Hervias-Caimapo, M. Hills, E. Hivon, B. Hu, T. Kisner, T. Kitching, E.D. Kovetz, H. Kurki-Suonio, L. Lamagna, M. Lattanzi, J. Lesgourgues, A. Lewis, V. Lindholm, J. Lizarraga, M. López-Caniego, G. Luzzi, B. Maffei, N. Mandolesi, E. Martínez-González, C.J.A.P. Martins, S. Masi, D. McCarthy, S. Matarrese, A. Melchiorri, J.-B. Melin, D. Molinari, A. Monfardini, P. Natoli, M. Negrello, A. Notari, F. Oppizzi, A. Paiella, E. Pajer, G. Patanchon, S.P. Patil, M. Piat, G. Pisano, L. Polastri, G. Polenta, A. Pollo, V. Poulin, M. Quartin, A. Ravenni, M. Remazeilles, A. Renzi, D. Roest, M. Roman, J.A. Rubiño-Martin, L. Salvati, A.A. Starobinsky, A. Tartari, G. Tasinato, M. Tomasi, J. Torrado, N. Trappe, T. Trombetti, M. Tucci, C. Tucker, J. Urrestilla, R. van de Weygaert, P. Vielva, N. Vittorio, K. Young, M. Zannoni, ITA, AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Institut Lagrange de Paris, Sorbonne Université (SU), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Théorique d'Orsay [Orsay] (LPT), Centre National de la Recherche Scientifique (CNRS)-Université Paris-Sud - Paris 11 (UP11), Institut de recherche en astrophysique et planétologie (IRAP), Institut national des sciences de l'Univers (INSU - CNRS)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Observatoire Midi-Pyrénées (OMP), Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Centre National de la Recherche Scientifique (CNRS), Institut d'Astrophysique de Paris (IAP), Institut national des sciences de l'Univers (INSU - CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Institut d'astrophysique spatiale (IAS), Université Paris-Sud - Paris 11 (UP11)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Institut Nanosciences et Cryogénie (INAC), Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Département de Physique des Particules (ex SPP) (DPP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Institut Néel (NEEL), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Université Pierre et Marie Curie - Paris 6 (UPMC), Laboratoire d'Annecy-le-Vieux de Physique Théorique (LAPTH), Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), CORE, Department of Physics, Helsinki Institute of Physics, Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), Sorbonne Universités, Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), Université Grenoble Alpes (UGA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Université Joseph Fourier - Grenoble 1 (UJF)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes (UGA), Université Grenoble Alpes (UGA)-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF), Finelli, F, Bucher, M, Achúcarro, A, Ballardini, M, Bartolo, N, Baumann, D, Clesse, S, Errard, J, Handley, W, Hindmarsh, M, Kiiveri, K, Kunz, M, Lasenby, A, Liguori, M, Paoletti, D, Ringeval, C, Väliviita, J, Tent, B, Vennin, V, Ade, P, Allison, R, Arroja, F, Ashdown, M, Banday, A, Banerji, R, Bartlett, J, Basak, S, de Bernardis, P, Bersanelli, M, Bonaldi, A, Borril, J, Bouchet, F, Boulanger, F, Brinckmann, T, Burigana, C, Buzzelli, A, Cai, Z, Calvo, M, Carvalho, C, Castellano, G, Challinor, A, Chluba, J, Colantoni, I, Coppolecchia, A, Crook, M, D'Alessandro, G, D'Amico, G, Delabrouille, J, Desjacques, V, Zotti, G, Diego, J, Valentino, E, Feeney, S, Fergusson, J, Fernandez-Cobos, R, Ferraro, S, Forastieri, F, Galli, S, García-Bellido, J, de Gasperis, G, Génova-Santos, R, Gerbino, M, González-Nuevo, J, Grandis, S, Greenslade, J, Hagstotz, S, Hanany, S, Hazra, D, Hernández-Monteagudo, C, Hervias-Caimapo, C, Hills, M, Hivon, E, Hu, B, Kisner, T, Kitching, T, Kovetz, E, Kurki-Suonio, H, Lamagna, L, Lattanzi, M, Lesgourgues, J, Lewis, A, Lindholm, V, Lizarraga, J, López-Caniego, M, Luzzi, G, Maffei, B, Mandolesi, N, Martínez-González, E, Martins, C, Masi, S, Mccarthy, D, Matarrese, S, Melchiorri, A, Melin, J, Molinari, D, Monfardini, A, Natoli, P, Negrello, M, Notari, A, Oppizzi, F, Paiella, A, Pajer, E, Patanchon, G, Patil, S, Piat, M, Pisano, G, Polastri, L, Polenta, G, Pollo, A, Poulin, V, Quartin, M, Ravenni, A, Remazeilles, M, Renzi, A, Roest, D, Roman, M, Rubiño-Martin, J, Salvati, L, Starobinsky, A, Tartari, A, Tasinato, G, Tomasi, M, Torrado, J, Trappe, N, Trombetti, T, Tucci, M, Tucker, C, Urrestilla, J, de Weygaert, R, Vielva, P, Vittorio, N, Young, K, Zannoni, M, Finelli F., Bucher M., Achucarro A., Ballardini M., Bartolo N., Baumann D., Clesse S., Errard J., Handley W., Hindmarsh M., Kiiveri K., Kunz M., Lasenby A., Liguori M., Paoletti D., Ringeval C., Valiviita J., Tent B.V., Vennin V., Ade P., Allison R., Arroja F., Ashdown M., Banday A.J., Banerji R., Bartlett J.G., Basak S., De Bernardis P., Bersanelli M., Bonaldi A., Borril J., Bouchet F.R., Boulanger F., Brinckmann T., Burigana C., Buzzelli A., Cai Z.-Y., Calvo M., Carvalho C.S., Castellano G., Challinor A., Chluba J., Colantoni I., Coppolecchia A., Crook M., D'Alessandro G., D'Amico G., Delabrouille J., Desjacques V., Zotti G.D., Diego J.M., Valentino E.D., Feeney S., Fergusson J.R., Fernandez-Cobos R., Ferraro S., Forastieri F., Galli S., Garcia-Bellido J., De Gasperis G., Genova-Santos R.T., Gerbino M., Gonzalez-Nuevo J., Grandis S., Greenslade J., Hagstotz S., Hanany S., Hazra D.K., Hernandez-Monteagudo C., Hervias-Caimapo C., Hills M., Hivon E., Hu B., Kisner T., Kitching T., Kovetz E.D., Kurki-Suonio H., Lamagna L., Lattanzi M., Lesgourgues J., Lewis A., Lindholm V., Lizarraga J., Lopez-Caniego M., Luzzi G., Maffei B., Mandolesi N., Martinez-Gonzalez E., Martins C.J.A.P., Masi S., McCarthy D., Matarrese S., Melchiorri A., Melin J.-B., Molinari D., Monfardini A., Natoli P., Negrello M., Notari A., Oppizzi F., Paiella A., Pajer E., Patanchon G., Patil S.P., Piat M., Pisano G., Polastri L., Polenta G., Pollo A., Poulin V., Quartin M., Ravenni A., Remazeilles M., Renzi A., Roest D., Roman M., Rubino-Martin J.A., Salvati L., Starobinsky A.A., Tartari A., Tasinato G., Tomasi M., Torrado J., Trappe N., Trombetti T., Tucci M., Tucker C., Urrestilla J., De Weygaert R.V., Vielva P., Vittorio N., Young K., Zannoni M., String Theory (ITFA, IoP, FNWI), High-Energy Frontier, Astronomy, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud - Paris 11 (UP11)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Centre National d’Études Spatiales [Paris] (CNES), Cryogénie (NEEL - Cryo), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Département de Physique des Particules (ex SPP) (DPhP), and Hélium : du fondamental aux applications (NEEL - HELFA)
Subjects: cosmological model, reheating, Cosmic microwave background, cosmic background radiation: polarization, SPECTRAL DISTORTIONS, astro-ph.CO, Astrophysics, cosmic background radiation, 7. Clean energy, 01 natural sciences, GRAVITATIONAL-WAVES, law.invention, law, 010303 astronomy & astrophysics, CMBR theory, ination, Astronomy and Astrophysics, CMBR theory, inflation, QC, QB, Physics, COSMIC cancer database, ST/J005673/1, ST/H008586/1, inflation: model, MICROWAVE BACKGROUND ANISOTROPY, Core inflation, Astrophysics - Cosmology and Nongalactic Astrophysics, Big Bang, scale: grand unified theory, Astrophysics and Astronomy, noise, Cosmology and Nongalactic Astrophysics (astro-ph.CO), STANDARD MODEL, satellite, FOS: Physical sciences, Astrophysics::Cosmology and Extragalactic Astrophysics, isocurvature: perturbation, frequency: high, PRIMORDIAL NON-GAUSSIANITY, NO, Telescope, power spectrum: primordial, FIS/05 - ASTRONOMIA E ASTROFISICA, Settore FIS/05 - Astronomia e Astrofisica, LARGE-SCALE STRUCTURE, 0103 physical sciences, inflation, cosmic string, STFC, MODEL SELECTION, Inflation (cosmology), non-Gaussianity: primordial, ST/K00333X/1, ISOCURVATURE PERTURBATIONS, 010308 nuclear & particles physics, string tension, big bang, inflation: slow-roll approximation, RCUK, Spectral density, 115 Astronomy, Space science, cosmic background radiation: temperature, Cosmic string, detector: sensitivity, angular resolution, 13. Climate action, PRE-BIG-BANG, BAYESIAN-INFERENCE, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], cosmic background radiation: anisotropy
Abstract: We forecast the scientific capabilities to improve our understanding of cosmic inflation of CORE, a proposed CMB space satellite submitted in response to the ESA fifth call for a medium-size mission opportunity. The CORE satellite will map the CMB anisotropies in temperature and polarization in 19 frequency channels spanning the range 60-600 GHz. CORE will have an aggregate noise sensitivity of $1.7 ��$K$\cdot \,$arcmin and an angular resolution of 5' at 200 GHz. We explore the impact of telescope size and noise sensitivity on the inflation science return by making forecasts for several instrumental configurations. This study assumes that the lower and higher frequency channels suffice to remove foreground contaminations and complements other related studies of component separation and systematic effects, which will be reported in other papers of the series "Exploring Cosmic Origins with CORE." We forecast the capability to determine key inflationary parameters, to lower the detection limit for the tensor-to-scalar ratio down to the $10^{-3}$ level, to chart the landscape of single field slow-roll inflationary models, to constrain the epoch of reheating, thus connecting inflation to the standard radiation-matter dominated Big Bang era, to reconstruct the primordial power spectrum, to constrain the contribution from isocurvature perturbations to the $10^{-3}$ level, to improve constraints on the cosmic string tension to a level below the presumptive GUT scale, and to improve the current measurements of primordial non-Gaussianities down to the $f_{NL}^{\rm local} < 1$ level. For all the models explored, CORE alone will improve significantly on the present constraints on the physics of inflation. Its capabilities will be further enhanced by combining with complementary future cosmological observations., Latex 107 pages, revised with updated author list and minor modifications
Published: 2018

19. Exploring cosmic origins with CORE: Gravitational lensing of the CMB

Author: A. Challinor, R. Allison, J. Carron, J. Errard, S. Feeney, T. Kitching, J. Lesgourgues, A. Lewis, Í. Zubeldía, A. Achucarro, P. Ade, M. Ashdown, M. Ballardini, A.J. Banday, R. Banerji, J. Bartlett, N. Bartolo, S. Basak, D. Baumann, M. Bersanelli, A. Bonaldi, M. Bonato, J. Borrill, F. Bouchet, F. Boulanger, T. Brinckmann, M. Bucher, C. Burigana, A. Buzzelli, Z.-Y. Cai, M. Calvo, C.-S. Carvalho, G. Castellano, J. Chluba, S. Clesse, I. Colantoni, A. Coppolecchia, M. Crook, G. d'Alessandro, P. de Bernardis, G. de Gasperis, G. De Zotti, J. Delabrouille, E. Di Valentino, J.-M. Diego, R. Fernandez-Cobos, S. Ferraro, F. Finelli, F. Forastieri, S. Galli, R. Genova-Santos, M. Gerbino, J. González-Nuevo, S. Grandis, J. Greenslade, S. Hagstotz, S. Hanany, W. Handley, C. Hernandez-Monteagudo, C. Hervías-Caimapo, M. Hills, E. Hivon, K. Kiiveri, T. Kisner, M. Kunz, H. Kurki-Suonio, L. Lamagna, A. Lasenby, M. Lattanzi, M. Liguori, V. Lindholm, M. López-Caniego, G. Luzzi, B. Maffei, E. Martinez-González, C.J.A.P. Martins, S. Masi, S. Matarrese, D. McCarthy, A. Melchiorri, J.-B. Melin, D. Molinari, A. Monfardini, P. Natoli, M. Negrello, A. Notari, A. Paiella, D. Paoletti, G. Patanchon, M. Piat, G. Pisano, L. Polastri, G. Polenta, A. Pollo, V. Poulin, M. Quartin, M. Remazeilles, M. Roman, J.-A. Rubino-Martin, L. Salvati, A. Tartari, M. Tomasi, D. Tramonte, N. Trappe, T. Trombetti, C. Tucker, J. Valiviita, R. Van de Weijgaert, B. van Tent, V. Vennin, P. Vielva, N. Vittorio, K. Young, M. Zannoni, Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris Diderot - Paris 7 (UPD7)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Institut Lagrange de Paris, Sorbonne Universités, AstroParticule et Cosmologie (APC (UMR_7164)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), Institut de recherche en astrophysique et planétologie (IRAP), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Observatoire Midi-Pyrénées (OMP), Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS), Institut d'Astrophysique de Paris (IAP), Institut national des sciences de l'Univers (INSU - CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Institut d'astrophysique spatiale (IAS), Université Paris-Sud - Paris 11 (UP11)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Institut Néel (NEEL), Université Grenoble Alpes (UGA)-Centre National de la Recherche Scientifique (CNRS)-Université Joseph Fourier - Grenoble 1 (UJF), Département de Physique des Particules (ex SPP) (DPP), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire d'Annecy-le-Vieux de Physique Théorique (LAPTH), Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Théorique d'Orsay [Orsay] (LPT), Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS), CORE, Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Sorbonne Université (SU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Institut national des sciences de l'Univers (INSU - CNRS)-Université Toulouse III - Paul Sabatier (UT3), Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Université Fédérale Toulouse Midi-Pyrénées-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Météo France-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD)-Centre National de la Recherche Scientifique (CNRS), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Centre National de la Recherche Scientifique (CNRS)-Université Paris-Sud - Paris 11 (UP11), Challinor, A, Allison, R, Carron, J, Errard, J, Feeney, S, Kitching, T, Lesgourgues, J, Lewis, A, Zubeldía, Í, Achucarro, A, Ade, P, Ashdown, M, Ballardini, M, Banday, A, Banerji, R, Bartlett, J, Bartolo, N, Basak, S, Baumann, D, Bersanelli, M, Bonaldi, A, Bonato, M, Borrill, J, Bouchet, F, Boulanger, F, Brinckmann, T, Bucher, M, Burigana, C, Buzzelli, A, Cai, Z, Calvo, M, Carvalho, C, Castellano, G, Chluba, J, Clesse, S, Colantoni, I, Coppolecchia, A, Crook, M, D'Alessandro, G, de Bernardis, P, de Gasperis, G, Zotti, G, Delabrouille, J, Valentino, E, Diego, J, Fernandez-Cobos, R, Ferraro, S, Finelli, F, Forastieri, F, Galli, S, Genova-Santos, R, Gerbino, M, González-Nuevo, J, Grandis, S, Greenslade, J, Hagstotz, S, Hanany, S, Handley, W, Hernandez-Monteagudo, C, Hervías-Caimapo, C, Hills, M, Hivon, E, Kiiveri, K, Kisner, T, Kunz, M, Kurki-Suonio, H, Lamagna, L, Lasenby, A, Lattanzi, M, Liguori, M, Lindholm, V, López-Caniego, M, Luzzi, G, Maffei, B, Martinez-González, E, Martins, C, Masi, S, Matarrese, S, Mccarthy, D, Melchiorri, A, Melin, J, Molinari, D, Monfardini, A, Natoli, P, Negrello, M, Notari, A, Paiella, A, Paoletti, D, Patanchon, G, Piat, M, Pisano, G, Polastri, L, Polenta, G, Pollo, A, Poulin, V, Quartin, M, Remazeilles, M, Roman, M, Rubino-Martin, J, Salvati, L, Tartari, A, Tomasi, M, Tramonte, D, Trappe, N, Trombetti, T, Tucker, C, Valiviita, J, de Weijgaert, R, Tent, B, Vennin, V, Vielva, P, Vittorio, N, Young, K, Zannoni, M, Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Helsinki Institute of Physics, Department of Physics, String Theory (ITFA, IoP, FNWI), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud - Paris 11 (UP11)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Centre National d’Études Spatiales [Paris] (CNES), Cryogénie (NEEL - Cryo), Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP )-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Département de Physique des Particules (ex SPP) (DPhP), and Hélium : du fondamental aux applications (NEEL - HELFA)
Subjects: deflection, Cosmic microwave background, cosmic background radiation: polarization, astro-ph.CO, Astrophysics, ST/N000927/1, ST/L000652/1, 7. Clean energy, 01 natural sciences, CMBR polarisation, gravitational lensing, inflation, neutrino masses from cosmology, ART. NO. 023003, estimator, neutrino: mass, 010303 astronomy & astrophysics, Physics, FLUCTUATIONS, GRAVITY-WAVES, Amplitude, non-Gaussianity, galaxy: cluster, Halo, gravitational radiation: power spectrum, Neutrino, CMBR polarization, gravitational lensing, ination, neutrino masses from cosmology, Astronomy and Astrophysics, Astrophysics - Cosmology and Nongalactic Astrophysics, CMBR polarisation, noise, Cosmology and Nongalactic Astrophysics (astro-ph.CO), B-mode: lens, FOS: Physical sciences, Astrophysics::Cosmology and Extragalactic Astrophysics, MASS, NO, FIS/05 - ASTRONOMIA E ASTROFISICA, Settore FIS/05 - Astronomia e Astrofisica, gravitation: lens, 0103 physical sciences, ddc:530, RECONSTRUCTION, inflation, Galaxy cluster, STFC, halo: mass, 010308 nuclear & particles physics, Gravitational wave, gravitational radiation: primordial, RCUK, 115 Astronomy, Space science, redshift, calibration, Redshift, Gravitational lens, CROSS-CORRELATION, RADIATION, neutrino: oscillation, GALAXY CLUSTERS, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], MICROWAVE BACKGROUND POLARIZATION, MATTER
Abstract: Lensing of the CMB is now a well-developed probe of large-scale clustering over a broad range of redshifts. By exploiting the non-Gaussian imprints of lensing in the polarization of the CMB, the CORE mission can produce a clean map of the lensing deflections over nearly the full-sky. The number of high-S/N modes in this map will exceed current CMB lensing maps by a factor of 40, and the measurement will be sample-variance limited on all scales where linear theory is valid. Here, we summarise this mission product and discuss the science that it will enable. For example, the summed mass of neutrinos will be determined to an accuracy of 17 meV combining CORE lensing and CMB two-point information with contemporaneous BAO measurements, three times smaller than the minimum total mass allowed by neutrino oscillations. In the search for B-mode polarization from primordial gravitational waves with CORE, lens-induced B-modes will dominate over instrument noise, limiting constraints on the gravitational wave power spectrum amplitude. With lensing reconstructed by CORE, one can "delens" the observed polarization internally, reducing the lensing B-mode power by 60%. This improves to 70% by combining lensing and CIB measurements from CORE, reducing the error on the gravitational wave amplitude by 2.5 compared to no delensing (in the null hypothesis). Lensing measurements from CORE will allow calibration of the halo masses of the 40000 galaxy clusters that it will find, with constraints dominated by the clean polarization-based estimators. CORE can accurately remove Galactic emission from CMB maps with its 19 frequency channels. We present initial findings that show that residual Galactic foreground contamination will not be a significant source of bias for lensing power spectrum measurements with CORE. [abridged], 44 pages, 12 figures
Published: 2018

20. Bilateral pallidal hemorrhage in toxoplasmosis update of acute symmetric lesions of deep nuclei

Author: Pasquale F. Finelli and Gregory L Wrubel
Subjects: Adult, Male, Pathology, medicine.medical_specialty, Antiprotozoal Agents, Infarction, Pallidal hemorrhage, Diagnosis, Differential, Level of consciousness, Neuroimaging, medicine, Humans, Radiology, Nuclear Medicine and imaging, AIDS-Related Opportunistic Infections, medicine.diagnostic_test, business.industry, Brain, Magnetic resonance imaging, General Medicine, medicine.disease, Magnetic Resonance Imaging, Toxoplasmosis, Toxoplasmosis, Cerebral, Etiology, Drug Therapy, Combination, Neurology (clinical), Differential diagnosis, Tomography, X-Ray Computed, business
Abstract: As acute symmetric lesions of deep gray nuclei are often associated with an impaired level of consciousness and neuroimaging by itself cannot distinguish between etiologies, diagnosis may be problematic. Appreciation of the cause of the various neuroimaging patterns in conjunction with the history, examination and laboratory investigations allows for accurate diagnosis in the vast majority of cases. Given the metabolic vulnerability of deep gray nuclei, other than bi-thalamic infarction, it follows that toxic-metabolic and hypoxic-ischemic events account for the majority of cases. Nevertheless, the differential diagnosis is broad and diverse. We here describe two cases of bilateral pallidal hemorrhage in AIDS-associated toxoplasmosis, and review conditions recently described with acute symmetric deep gray nuclei lesions on neuroimaging.
Published: 2015

21. Abstract WP54: Early MRI Facilitates Stroke Evaluation and Decreases Length of Stay for Ischemic Stroke Patients

Author: Ilene Staff, Nora Lee, Bharti Manwani, Pasquale F. Finelli, Subhendu Rath, Gilbert Fortunato, Matthew R. Woodward, Christopher Stretz, and Jahanavi Modak
Subjects: Advanced and Specialized Nursing, medicine.medical_specialty, medicine.diagnostic_test, business.industry, medicine.medical_treatment, Magnetic resonance imaging, medicine.disease, Internal medicine, Ischemic stroke, medicine, Cardiology, Neurology (clinical), Cardiology and Cardiovascular Medicine, business, Stroke recovery, Stroke, Acute hemorrhage
Abstract: Background: Imaging studies are an integral part of stroke evaluation and non-contrast head CT is the initial imaging modality. Although critical for assessing acute hemorrhage, ischemic changes may not be visible on CT for up to 24 hours. MRI brain detects ischemic changes within 20 minutes of symptom onset. It is an invaluable tool to confirm an ischemic stroke and determine its etiology. A focused workup for stroke etiology or evaluation for stroke mimics accelerates management strategies and reduces length of stay in the hospital. Early discharge facilitates early rehabilitation and better functional recovery of stroke patients. Current guidelines for management of acute stroke recommend head CT within 25 minutes of presentation. However, to date, a recommendation regarding timeline for MRI brain in stroke evaluation is lacking. Objective of this study was to investigate the correlation between time to MRI & length of hospital stay to functional outcome in stroke patients. Methods: 648 patients (mean age 69±0.5 years; 50.4% women) admitted to Hartford Hospital (Comprehensive Stroke Center) with a focal neurological deficit in the year 2014 and got a CT head and MRI brain were enrolled in the study. Data collection was done via stroke database and retrospective chart review. Patients with any hemorrhage or age Results: There was a significant effect of time from arrival to MRI on length of hospital stay (r=0.27, p Conclusions: Our study indicates that delay in MRI for a suspected stroke increases hospital length of stay. It suggests MRI within 12 hours of admission to be the new standard of care for stroke patients. Ongoing work will assess the correlation of timing to MRI to functional outcomes in stroke patients.
Published: 2017

22. Diffusion-Weighted Imaging in Acute Hyperammonemic Encephalopathy

Author: Michael Rosario, Pasquale F. Finelli, and Kevin McMahon
Subjects: Cerebral atrophy, Pathology, medicine.medical_specialty, medicine.diagnostic_test, business.industry, Thalamus, Magnetic resonance imaging, medicine.disease, Hyperintensity, Liver disease, Globus pallidus, Short Reports, nervous system, medicine, Neurology (clinical), business, Hepatic encephalopathy, Diffusion MRI
Abstract: Magnetic resonance imaging (MRI) findings associated with chronic liver disease are characterized by cerebral atrophy and bilateral, symmetric hyperintensities of the globus pallidus on T1-weighted images without corresponding signal intensities in T2-weighted images. Recently, distinct MRI changes of acute hepatic encephalopathy have been described which may be misinterpreted given their resemblance to hypoxic-ischemic injury imaging changes as well as their limited description in the neurologic literature. We describe 3 cases of acute hyperammonemic encephalopathy primarily characterized by restricted diffusion involving the insular and cingulate cortices and thalamus bilaterally.
Published: 2013

23. Herpes simplex encephalitis in an immunocompromised adult with novel MRI and pathology findings

Author: Janhavi Modak, Avinash Prasad, Pasquale F. Finelli, and Xianyuan Song
Subjects: Adult, Male, Pathology, medicine.medical_specialty, Neurology, MEDLINE, Acyclovir, Antiviral Agents, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, Immunocompromised Host, 0302 clinical medicine, medicine, Humans, Radiology, Nuclear Medicine and imaging, Neuroradiology, Cerebral Cortex, medicine.diagnostic_test, business.industry, Magnetic resonance imaging, Middle Aged, medicine.disease, Magnetic Resonance Imaging, Encephalitis, Neurology (clinical), Neurosurgery, Encephalitis, Herpes Simplex, business, 030217 neurology & neurosurgery
Published: 2016

24. Computer-assisted Diagnostic Checklist in Clinical Neurology

Author: Pasquale F. Finelli and Andrew L. McCabe
Subjects: Male, Process (engineering), 03 medical and health sciences, 0302 clinical medicine, Key terms, Internet based, Human–computer interaction, Anemia, Pernicious, Medicine, Humans, 030212 general & internal medicine, Diagnosis, Computer-Assisted, Computer device, business.industry, Brain Neoplasms, Infant, General Medicine, Middle Aged, Checklist, Clinical neurology, Term (time), Leukodystrophy, Globoid Cell, Neurology, Key (cryptography), Female, Neurology (clinical), business, 030217 neurology & neurosurgery, Algorithms
Abstract: Considering computers are more efficient at processing large amounts of information than the human brain, speaks to the need to explore more intelligent computer-assisted diagnostic approaches. Two diagnostic checklist programs, one for single key term entry (NeurologyINDEX), and another, with more advanced algorithms to process multiple key terms and perform additional functions (NeurologicDx) are discussed. Both programs are internet based, access the same database, and are designed to generate diagnostic checklists and disease profiles accessible with hand-held or other computer device. The development of systems that use "smart algorithms" to generate valid diagnostic checklists is the goal.
Published: 2016

25. Posters * Fertility Preservation

Author: R. Talevi, V. Barbato, V. Mollo, C. De Stefano, F. Finelli, R. Ferraro, R. Gualtieri, P. Zhou, A. H. Liu, Y. X. Cao, H. Roman, I. Pura, O. Tarta, N. Bourdel, L. Marpeau, J. C. Sabourin, M. Portmann, Z. P. Nagy, B. Behr, B. Alvaro Mercadal, I. Demeestere, R. Imbert, Y. Englert, A. Delbaere, S. Lueke, N. Buendgen, F. Koester, K. Diedrich, G. Griesinger, A. Kim, J. E. Han, C. Eunmi, Y. S. Kim, J. H. Cho, T. K. Yoon, P. Piomboni, A. Stendardi, D. Palumberi, G. Morgante, V. De Leo, F. Serafini, R. Focarelli, C. Tatone, G. Di Emidio, M. C. Carbone, M. Vento, R. Ciriminna, P. G. Artini, K. Kyono, T. Ishikawa, K. Usui, M. Hatori, L. Yasmin, E. Sato, M. Iwasaka, K. Fujii, N. Owada, T. Sankai, M. McLaughlin, P. Fineron, R. A. Anderson, W. H. B. Wallace, E. E. Telfer, S. Labied, A. Beliard, C. Munaut, J. M. Foidart, I. Turkcuoglu, K. Oktay, K. Rodriguez-Wallberg, M. Kuwayama, Y. Takayama, C. Mori, N. Kagawa, N. Akakubo, Y. Takehara, K. Kato, S. P. Leibo, O. Kato, H. Yoon, Y. Shin, J. cha, H. Kim, W. Lee, S. Yoon, J. Lim, M. G. Larman, D. K. Gardner, D. Zander-Fox, M. Lane, H. Hamilton, S. Lee, S. Ozkavukcu, E. Heytens, R. M. Alappat, M. Sole, M. Boada, M. Biadiu, J. Santalo, B. Coroleu, P. N. Barri, A. Veiga, L. Rossi, R. Bartoletti, M. Mengarelli, G. Boccia Artieri, L. Gemini, L. Mazzoli, L. Giannini, G. Scaravelli, S. J. Silber, S. Yamanguchi, Y. Nagumo, Y. Takai, S. Ishihara, R. Soleimani, I. Rottiers, A. Gojayev, A. C. Cuvelier, P. De Sutter, M. Salama, K. Winkler, K. F. Murach, S. Hofer, L. Wildt, S. C. Friess, N. Okumura, N. Kuji, A. Kishimi, H. Nishio, Y. Mochimaru, K. Minegishi, K. Miyakoshi, T. Fujii, M. Tanaka, D. Aoki, Y. Yoshimura, K. Hasegawa, S. Juanzi, W. Zhao, S. Zhang, X. Xue, S. Silber, J. Zhang, D. Meirow, R. Gosden, J. R. Westphal, R. Gerritse, C. C. M. Beerendonk, D. D. M. Braat, R. Peek, G. Coticchio, M. Dal Canto, F. Brambillasca, M. Mignini Renzini, M. Merola, M. Lain, R. Fadini, S. A. Nottola, E. Albani, C. Lorenzo, T. Carlini, M. Maione, A. Borini, G. Macchiarelli, P. E. Levi-Setti, L. Rienzi, S. Romano, A. Capalbo, B. Iussig, L. Albricci, S. Colamaria, E. Baroni, F. Sapienza, M. Giuliani, R. Anniballo, F. M. Ubaldi, D. A. Beyer, A. Schultze-Mosgau, F. Amari, S. Al-Hasani, S. Resta, M. C. Magli, A. Ruberti, M. Lappi, A. P. Ferraretti, L. Gianaroli, N. Prisant, S. Belloc, M. Cohen-Bacrie, A. Hazout, F. Olivennes, F. X. Aubriot, S. Alvarez, J. De Mouzon, C. Thieulin, P. Cohen-Bacrie, S. Wozniak, P. Szkodziak, E. Wozniakowska, M. Paszkowski, T. Paszkowski, D. Diaz, S. Dragnic, B. Hayward, R. Bennett, A. Al-Sabbagh, E. Novella-Maestre, J. Teruel, L. Carmona, E. Rosello, A. Pellicer, M. Sanchez-Serrano, J. R. Lee, J. Y. Lee, C. H. Kim, Y. Lee, B. C. Jee, C. S. Suh, S. H. Kim, S. Y. Moon, V. Mirabet, J. Crespo, M. Schiewe, N. Nugent, S. Zozula, R. Anderson, J. F. Zulategui, M. Meseguer, J. Remohi, D. Castello, J. L. L. Romero, M. J. De los Santos, A. C. Cobo, M. von Wolff, J. Jauckus, M. Kupka, T. Strowitzki, B. Lawrenz, H. Raanani, B. Kaufman, E. Maman, M. M. Mendel, J. Dor, N. K. Buendgen, C. Combelles, H. Y. Wang, C. Racowsky, L. Kuleshova, M. Tucker, J. Graham, K. Richter, J. Carter, and M. Levy
Subjects: Gynecology, Pathology, medicine.medical_specialty, Ideal (set theory), Reproductive Medicine, business.industry, Ovarian tissue, Rehabilitation, medicine, Obstetrics and Gynecology, business
Published: 2010

26. Cerebral Amyloid Angiopathy as Cause of Convexity SAH in Elderly

Author: Pasquale F. Finelli
Subjects: Male, medicine.medical_specialty, Subarachnoid hemorrhage, Hemosiderosis, Convexity, mental disorders, medicine, Humans, cardiovascular diseases, Aged, Aged, 80 and over, medicine.diagnostic_test, business.industry, Brain, nutritional and metabolic diseases, Magnetic resonance imaging, General Medicine, Subarachnoid Hemorrhage, medicine.disease, Magnetic Resonance Imaging, Mr imaging, nervous system diseases, body regions, Cerebral Amyloid Angiopathy, Etiology, Female, Neurology (clinical), Cerebral amyloid angiopathy, Radiology, business
Abstract: Background Spontaneous convexity SAH in the elderly has heretofore been of uncertain origin until several recent case reports have suggested cerebral amyloid angiopathy (CAA) as the etiology. Objective To better appreciate the relationship of convexity SAH in the elderly to CAA. Method The case histories and MR imaging findings of 4 patients with spontaneous convexity SAH were examined. Results T2*-weighted imaging at the time of symptomatic SAH demonstrated features of prior lobar hemorrhage, microbleeds, and/or superficial hemosiderosis fulfilling diagnostic criteria of CAA in all patients. Conclusions CAA may be the foremost cause of convexity SAH in the elderly.
Published: 2010

27. Magnetic Resonance Correlate of Hemiparesis in Posterior Cerebral Artery Infarction

Author: Pasquale F. Finelli
Subjects: Male, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, Tegmentum Mesencephali, Pyramidal Tracts, Infarction, Posterior cerebral artery, Fluid-attenuated inversion recovery, Efferent Pathways, Magnetic resonance angiography, Infarction, Posterior Cerebral Artery, Predictive Value of Tests, medicine.artery, Posterior Choroidal Artery, medicine, Humans, Aged, Aged, 80 and over, Posterior Cerebral Artery, medicine.diagnostic_test, Thalamogeniculate artery, Cerebral infarction, business.industry, Cerebral peduncle, Rehabilitation, medicine.disease, Paresis, Circle of Willis, Female, Surgery, Neurology (clinical), Radiology, Cardiology and Cardiovascular Medicine, business, Magnetic Resonance Angiography
Abstract: Background Magnetic resonance (MR) imaging of posterior cerebral artery infarction with hemiparesis (PCAH) is limited to case reports with T2-weighted lesions involving the cerebral peduncle. Objective We sought to extend the MR imaging correlate of PCAH. Methods The case histories and MR/MR angiography findings of 4 patients with PCAH were examined. Results Distinct from previously described MR imaging findings with PCAH, diffusion-weighted imaging and/or FLAIR changes were noted in the thalamogeniculate artery (TGA) territory in one patient; in the distribution of the TGA and lateral posterior choroidal artery (PChA) in two patients; and in the TGA and lateral PChA combined with the peduncular perforating arteries of the cerebral peduncle in one patient. Conclusion Diffusion-weighted imaging changes of infarction in the distribution of the TGA alone or combined with lateral PChA involvement with or without cerebral peduncle infarction correlate with PCAH.
Published: 2008

28. SPACE: the spectroscopic all-sky cosmic explorer

Author: A. Cimatti, M. Robberto, C. Baugh, S. V. W. Beckwith, R. Content, E. Daddi, G. De Lucia, B. Garilli, L. Guzzo, G. Kauffmann, M. Lehnert, D. Maccagni, A. Martínez-Sansigre, F. Pasian, I. N. Reid, P. Rosati, R. Salvaterra, M. Stiavelli, Y. Wang, M. Zapatero Osorio, M. Balcells, M. Bersanelli, F. Bertoldi, J. Blaizot, D. Bottini, R. Bower, A. Bulgarelli, A. Burgasser, C. Burigana, R. C. Butler, S. Casertano, B. Ciardi, M. Cirasuolo, M. Clampin, S. Cole, A. Comastri, S. Cristiani, J.-G. Cuby, F. Cuttaia, A. De Rosa, A. Diaz Sanchez, M. Di Capua, J. Dunlop, X. Fan, A. Ferrara, F. Finelli, A. Franceschini, M. Franx, P. Franzetti, C. Frenk, Jonathan P. Gardner, F. Gianotti, R. Grange, C. Gruppioni, A. Gruppuso, F. Hammer, L. Hillenbrand, A. Jacobsen, M. Jarvis, R. Kennicutt, R. Kimble, M. Kriek, J. Kurk, J.-P. Kneib, O. Le Fevre, D. Macchetto, J. MacKenty, P. Madau, M. Magliocchetti, D. Maino, N. Mandolesi, N. Masetti, R. McLure, A. Mennella, M. Meyer, M. Mignoli, B. Mobasher, E. Molinari, G. Morgante, S. Morris, L. Nicastro, E. Oliva, P. Padovani, E. Palazzi, F. Paresce, A. Perez Garrido, E. Pian, L. Popa, M. Postman, L. Pozzetti, J. Rayner, R. Rebolo, A. Renzini, H. Röttgering, E. Schinnerer, M. Scodeggio, M. Saisse, T. Shanks, A. Shapley, R. Sharples, H. Shea, J. Silk, I. Smail, P. Spanó, J. Steinacker, L. Stringhetti, A. Szalay, L. Tresse, M. Trifoglio, M. Urry, L. Valenziano, F. Villa, I. Villo Perez, F. Walter, M. Ward, R. White, S. White, E. Wright, R. Wyse, G. Zamorani, A. Zacchei, W. W. Zeilinger, F. Zerbi, Alma Mater Studiorum Università di Bologna [Bologna] (UNIBO), Space Telescope Science Institute (STScI), Institute for Computational Cosmology, Department of Physics, Durham University, Durham (ICC), Centre for Advanced Instrumentation, Department of Physics, Durham University (CfAI), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Max-Planck-Institut für Astrophysik (MPA), Istituto di Astrofisica Spaziale e Fisica Cosmica - Milano (IASF-MI), Istituto Nazionale di Astrofisica (INAF), Brera, Galaxies, Etoiles, Physique, Instrumentation (GEPI), Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Physique des Galaxies et Cosmologie, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS), Max-Planck-Institut für Astronomie (MPIA), INAF-Osservatorio Astronomico di Trieste (INAF-OATs), European Southern Observatory (ESO), Università di Milano, University of Oklahoma, Instituto de Astrofísica de Canarias (IAC), Rheinische Friedrich-Wilhelms-Universität Bonn, Istituto di Astrofisica Spaziale e Fisica Cosmica (IASF-Bologna), Department of Earth Atmospheric and Planetary Sciences, MIT, The Royal Observatory (ROE), Goddard Space Flight Center, NASA, Astrophysics Science Division, INAF-Osservatorio Astronomico di Bologna (OABO), Laboratoire d'Astrophysique de Marseille (LAM), Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS), Universidad Politecnica de Cartagena (UPCT), University of Maryland, University of Arizona, Scuola Internazionale Superiore di Studi Avanzati (SISSA), Università degli Studi di Padova = University of Padua (Unipd), University of Leiden, California Institute of Technology, Department of Astronomy (CALTECH), OpSys Project Consulting, University of Hertfordshire [Hatfield] (UH), Institute of Astronomy, University of Cambridge (IoA), Research and Scientific Support Department, ESA-ESTEC (RSSD), University of California, Santa Cruz (UCSC), Steward Observatory, University of Arizona, UC Riverside, INAF-Osservatorio Astrofisico di Arcetri (INAF-OAA), University of Bucharest, Institute for Astronomy, University of Hawaii, INAF-Osservatorio Astronomico di Padova, Princeton, Ecole Polytechnique Fédérale de Lausanne (EPFL), University of Oxford, Johns Hopkins University (JHU), Yale University, University of California, Los Angeles (UCLA), University of Vienna, Cimatti A., Robberto M., Baugh C., Beckwith S. V. W., Content R., Daddi E., De Lucia G., Garilli B., Guzzo L., Kauffmann G., Lehnert M., Maccagni D., Martínez-Sansigre A., Pasian F., Reid I. N., Rosati P., Salvaterra R., Stiavelli M., Wang Y., Osorio M. Zapatero, Balcells M., Bersanelli M., Bertoldi F., Blaizot J., Bottini D., Bower R., Bulgarelli A., Burgasser A., Burigana C., Butler R. C., Casertano S., Ciardi B., Cirasuolo M., Clampin M., Cole S., Comastri A., Cristiani S., Cuby J.-G., Cuttaia F., de Rosa A., Sanchez A. Diaz, di Capua M., Dunlop J., Fan X., Ferrara A., Finelli F., Franceschini A., Franx M., Franzetti P., Frenk C., Gardner Jonathan P., Gianotti F., Grange R., Gruppioni C., Gruppuso A., Hammer F., Hillenbrand L., Jacobsen A., Jarvis M., Kennicutt R., Kimble R., Kriek M., Kurk J., Kneib J.-P., Le Fevre O., Macchetto D., MacKenty J., Madau P., Magliocchetti M., Maino D., Mandolesi N., Masetti N., McLure R., Mennella A., Meyer M., Mignoli M., Mobasher B., Molinari E., Morgante G., Morris S., Nicastro L., Oliva E., Padovani P., Palazzi E., Paresce F., Garrido A. Perez, Pian E., Popa L., Postman M., Pozzetti L., Rayner J., Rebolo R., Renzini A., Röttgering H., Schinnerer E., Scodeggio M., Saisse M., Shanks T., Shapley A., Sharples R., Shea H., Silk J., Smail I., Spanó P., Steinacker J., Stringhetti L., Szalay A., Tresse L., Trifoglio M., Urry M., Valenziano L., Villa F., Perez I. Villo, Walter F., Ward M., White R., White S., Wright E., Wyse R., Zamorani G., Zacchei A., Zeilinger W., Zerbi F., Cimatti, A., Robberto, M., Baugh, C., Beckwith, S. V. W., Content, R., Daddi, E., De, Lucia, G., Garilli, B., Guzzo, L., Kauffmann, Ferrara, Andrea, and 113, Coauthors
Subjects: Observational cosmology, media_common.quotation_subject, FOS: Physical sciences, Astrophysics::Cosmology and Extragalactic Astrophysics, Astrophysics, Space (mathematics), law.invention, Telescope, law, Dark energy, Spectral resolution, media_common, Physics, COSMIC cancer database, Astronomical and space-research instrumentation, Astrophysics (astro-ph), Astrophysics::Instrumentation and Methods for Astrophysics, Astronomy and Astrophysics, Billion years, Galaxy, Redshift, Space and Planetary Science, Sky, Astrophysics::Earth and Planetary Astrophysics, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]
Abstract: We describe the scientific motivations, the mission concept and the instrumentation of SPACE, a class-M mission proposed for concept study at the first call of the ESA Cosmic-Vision 2015-2025 planning cycle. SPACE aims to produce the largest three-dimensional evolutionary map of the Universe over the past 10 billion years by taking near-IR spectra and measuring redshifts for more than half a billion galaxies at 0, Comment: 27 pages, Experimental Astronomy, in press. The SPACE team complete list is available at http://urania.bo.astro.it/cimatti/space . The article with full resolution figures is available at http://urania.bo.astro.it/cimatti/space/publications.htm
Published: 2008

29. Planck Intermediate Results. IV. The XMM-Newton validation programme for new Planck clusters

Author: P. A. R. Ade, N. Aghanim, M. Arnaud, M. Ashdown, J. Aumont, C. Baccigalupi, A. Balbi, A. J. Banday, R. B. Barreiro, J. G. Bartlett, E. Battaner, K. Benabed, A. Benoît, J. P. Bernard, M. Bersanelli, I. Bikmaev, H. Böhringer, A. Bonaldi, J. R. Bond, J. Borrill, F. R. Bouchet, M. L. Brown, C. Burigana, R. C. Butler, P. Cabella, P. Carvalho, A. Catalano, L. Cayón, A. Chamballu, R. R. Chary, L. Y. Chiang, G. Chon, P. R. Christensen, D. L. Clements, S. Colafrancesco, S. Colombi, A. Coulais, B. P. Crill, F. Cuttaia, A. Da Silva, H. Dahle, R. J. Davis, P. de Bernardis, G. de Gasperis, G. de Zotti, J. Delabrouille, J. Démoclès, F. X. Désert, J. M. Diego, K. Dolag, H. Dole, S. Donzelli, O. Doré, M. Douspis, X. Dupac, T. A. Enßlin, H. K. Eriksen, F. Finelli, I. Flores Cacho, O. Forni, M. Frailis, E. Franceschi, M. Frommert, S. Galeotta, K. Ganga, R. T. Génova Santos, Y. Giraud Héraud, J. González Nuevo, R. González Riestra, K. M. Górski, A. Gruppuso, F. K. Hansen, D. Harrison, A. Hempel, S. Henrot Versillé, C. Hernández Monteagudo, D. Herranz, S. R. Hildebrandt, E. Hivon, M. Hobson, W. A. Holmes, A. Hornstrup, W. Hovest, K. M. Huffenberger, G. Hurier, A. H. Jaffe, T. Jagemann, W. C. Jones, M. Juvela, R. Kneissl, J. Knoche, L. Knox, M. Kunz, H. Kurki Suonio, G. Lagache, J. M. Lamarre, A. Lasenby, C. R. Lawrence, M. Le Jeune, S. Leach, R. Leonardi, A. Liddle, P. B. Lilje, M. Linden Vørnle, M. López Caniego, G. Luzzi, J. F. Macías Pérez, D. Maino, N. Mandolesi, R. Mann, M. Maris, F. Marleau, D. J. Marshall, E. Martínez González, S. Masi, M. Massardi, S. Matarrese, P. Mazzotta, S. Mei, P. R. Meinhold, A. Melchiorri, J. B. Melin, L. Mendes, A. Mennella, S. Mitra, M. A. Miville Deschênes, A. Moneti, G. Morgante, D. Mortlock, D. Munshi, P. Naselsky, F. Nati, P. Natoli, H. U. Nørgaard Nielsen, F. Noviello, S. Osborne, F. Pajot, D. Paoletti, O. Perdereau, F. Perrotta, F. Piacentini, M. Piat, E. Pierpaoli, R. Piffaretti, S. Plaszczynski, P. Platania, E. Pointecouteau, G. Polenta, L. Popa, T. Poutanen, G. W. Pratt, S. Prunet, J. L. Puget, M. Reinecke, M. Remazeilles, C. Renault, S. Ricciardi, G. Rocha, C. Rosset, M. Rossetti, J. A. Rubiño Martín, B. Rusholme, M. Sandri, G. Savini, D. Scott, G. F. Smoot, A. Stanford, F. Stivoli, R. Sudiwala, R. Sunyaev, D. Sutton, A. S. Suur Uski, J. F. Sygnet, J. A. Tauber, L. Terenzi, L. Toffolatti, M. Tomasi, M. Tristram, L. Valenziano, B. Van Tent, P. Vielva, F. Villa, N. Vittorio, L. A. Wade, B. D. Wandelt, N. Welikala, J. Weller, S. D. M. White, D. Yvon, A. Zacchei, A. Zonca, BORGANI, STEFANO, GREGORIO, ANNA, P. A. R., Ade, N., Aghanim, M., Arnaud, M., Ashdown, J., Aumont, C., Baccigalupi, A., Balbi, A. J., Banday, R. B., Barreiro, J. G., Bartlett, E., Battaner, K., Benabed, A., Benoît, J. P., Bernard, M., Bersanelli, I., Bikmaev, H., Böhringer, A., Bonaldi, J. R., Bond, Borgani, Stefano, J., Borrill, F. R., Bouchet, M. L., Brown, C., Burigana, R. C., Butler, P., Cabella, P., Carvalho, A., Catalano, L., Cayón, A., Chamballu, R. R., Chary, L. Y., Chiang, G., Chon, P. R., Christensen, D. L., Clement, S., Colafrancesco, S., Colombi, A., Coulai, B. P., Crill, F., Cuttaia, A., Da Silva, H., Dahle, R. J., Davi, P., de Bernardi, G., de Gasperi, G., de Zotti, J., Delabrouille, J., Démoclè, F. X., Désert, J. M., Diego, K., Dolag, H., Dole, S., Donzelli, O., Doré, M., Douspi, X., Dupac, T. A., Enßlin, H. K., Eriksen, F., Finelli, I., Flores Cacho, O., Forni, M., Fraili, E., Franceschi, M., Frommert, S., Galeotta, K., Ganga, R. T., Génova Santo, Y., Giraud Héraud, J., González Nuevo, R., González Riestra, K. M., Górski, Gregorio, Anna, A., Gruppuso, F. K., Hansen, D., Harrison, A., Hempel, S., Henrot Versillé, C., Hernández Monteagudo, D., Herranz, S. R., Hildebrandt, E., Hivon, M., Hobson, W. A., Holme, A., Hornstrup, W., Hovest, K. M., Huffenberger, G., Hurier, A. H., Jaffe, T., Jagemann, W. C., Jone, M., Juvela, R., Kneissl, J., Knoche, L., Knox, M., Kunz, H., Kurki Suonio, G., Lagache, J. M., Lamarre, A., Lasenby, C. R., Lawrence, M., Le Jeune, S., Leach, R., Leonardi, A., Liddle, P. B., Lilje, M., Linden Vørnle, M., López Caniego, G., Luzzi, J. F., Macías Pérez, D., Maino, N., Mandolesi, R., Mann, M., Mari, F., Marleau, D. J., Marshall, E., Martínez González, S., Masi, M., Massardi, S., Matarrese, P., Mazzotta, S., Mei, P. R., Meinhold, A., Melchiorri, J. B., Melin, L., Mende, A., Mennella, S., Mitra, M. A., Miville Deschêne, A., Moneti, G., Morgante, D., Mortlock, D., Munshi, P., Naselsky, F., Nati, P., Natoli, H. U., Nørgaard Nielsen, F., Noviello, S., Osborne, F., Pajot, D., Paoletti, O., Perdereau, F., Perrotta, F., Piacentini, M., Piat, E., Pierpaoli, R., Piffaretti, S., Plaszczynski, P., Platania, E., Pointecouteau, G., Polenta, L., Popa, T., Poutanen, G. W., Pratt, S., Prunet, J. L., Puget, M., Reinecke, M., Remazeille, C., Renault, S., Ricciardi, G., Rocha, C., Rosset, M., Rossetti, J. A., Rubiño Martín, B., Rusholme, M., Sandri, G., Savini, D., Scott, G. F., Smoot, A., Stanford, F., Stivoli, R., Sudiwala, R., Sunyaev, D., Sutton, A. S., Suur Uski, J. F., Sygnet, J. A., Tauber, L., Terenzi, L., Toffolatti, M., Tomasi, M., Tristram, L., Valenziano, B., Van Tent, P., Vielva, F., Villa, N., Vittorio, L. A., Wade, B. D., Wandelt, N., Welikala, J., Weller, S. D. M., White, D., Yvon, A., Zacchei, and A., Zonca
Subjects: galaxies: clusters: intracluster medium, clusters: intracluster medium [galaxies], galaxies: clusters: general, cosmology: observations, X-rays: galaxies: clusters, clusters: general [galaxies], galaxies: clusters [X-rays], cosmic background radiation, observation [cosmology]
Abstract: We present the final results from the XMM-Newton validation follow-up of new Planck galaxy cluster candidates. We observed 15 new candidates, detected with signal-to-noise ratios between 4.0 and 6.1 in the 15.5-month nominal Planck survey. The candidates were selected using ancillary data flags derived from the ROSAT All Sky Survey (RASS) and Digitized Sky Survey all-sky maps, with the aim of pushing into the low SZ flux, high-z regime and testing RASS flags as indicators of candidate reliability. Fourteen new clusters were detected by XMM-Newton, ten single clusters and two double systems. Redshifts from X-ray spectroscopy lie in the range 0.2 to 0.9, with six clusters at z > 0.5. Estimated masses (M500) range from 2.5 × 1014 to 8 × 1014 M⊙. We discuss our results in the context of the full XMM-Newton validation programme, in which 51 new clusters have been detected. This includes four double and two triple systems, some of which are chance projections on the sky of clusters at different redshifts. We find thatassociation with a source from the RASS-Bright Source Catalogue is a robust indicator of the reliability of a candidate, whereas association with a source from the RASS-Faint Source Catalogue does not guarantee that the SZ candidate is a bona fide cluster. Nevertheless, most Planck clusters appear in RASS maps, with a significance greater than 2σ being a good indication that the candidate is a real cluster. Candidate validation from association with SDSS galaxy overdensity at z > 0.5 is also discussed. The full sample gives a Planck sensitivity threshold of Y500 ~ 4 × 10-4 arcmin2, with indication for Malmquist bias in the YX-Y500 relation below this threshold. The corresponding mass threshold depends on redshift. Systems with M500 > 5 × 1014 M⊙ at z > 0.5 are easily detectable with Planck. The newly-detected clusters follow the YX-Y500 relation derived from X-ray selected samples. Compared to X-ray selected clusters, the new SZ clusters have a lower X-ray luminosity on average for their mass. There is no indication of departure from standard self-similar evolution in the X-ray versus SZ scaling properties. In particular, there is no significant evolution of the YX / Y500 ratio.
Published: 2013

30. Planckintermediate results(Corrigendum)

Author: P. A. R. Ade, N. Aghanim, M. Arnaud, M. Ashdown, F. Atrio Barandela, J. Aumont, C. Baccigalupi, A. Balbi, A. J. Banday, R. B. Barreiro, J. G. Bartlett, E. Battaner, K. Benabed, A. Benoît, J. P. Bernard, M. Bersanelli, R. Bhatia, I. Bikmaev, J. Bobin, H. Böhringer, A. Bonaldi, J. R. Bond, J. Borrill, F. R. Bouchet, H. Bourdin, M. L. Brown, R. Burenin, C. Burigana, P. Cabella, J. F. Cardoso, P. Carvalho, G. Castex, A. Catalano, L. Cayón, A. Chamballu, L. Y. Chiang, G. Chon, P. R. Christensen, E. Churazov, D. L. Clements, S. Colafrancesco, S. Colombi, L. P. L. Colombo, B. Comis, A. Coulais, B. P. Crill, F. Cuttaia, A. Da Silva, H. Dahle, L. Danese, R. J. Davis, P. de Bernardis, G. de Gasperis, G. de Zotti, J. Delabrouille, J. Démoclès, F. X. Désert, J. M. Diego, K. Dolag, H. Dole, S. Donzelli, O. Doré, U. Dörl, M. Douspis, X. Dupac, G. Efstathiou, T. A. Enßlin, H. K. Eriksen, F. Finelli, I. Flores Cacho, O. Forni, P. Fosalba, M. Frailis, E. Franceschi, M. Frommert, S. Galeotta, K. Ganga, R. T. Génova Santos, M. Giard, Y. Giraud Héraud, J. González Nuevo, K. M. Górski, GREGORIO, ANNA, A. Gruppuso, F. K. Hansen, D. Harrison, A. Hempel, S. Henrot Versillé, C. Hernández Monteagudo, D. Herranz, S. R. Hildebrandt, E. Hivon, M. Hobson, W. A. Holmes, G. Hurier, T. R. Jaffe, A. H. Jaffe, T. Jagemann, W. C. Jones, M. Juvela, E. Keihänen, I. Khamitov, T. S. Kisner, R. Kneissl, J. Knoche, L. Knox, M. Kunz, H. Kurki Suonio, G. Lagache, A. Lähteenmäki, J. M. Lamarre, A. Lasenby, C. R. Lawrence, M. Le Jeune, R. Leonardi, A. Liddle, P. B. Lilje, M. López Caniego, G. Luzzi, J. F. Macías Pérez, D. Maino, N. Mandolesi, M. Maris, F. Marleau, D. J. Marshall, E. Martínez González, S. Masi, M. Massardi, S. Matarrese, P. Mazzotta, S. Mei, A. Melchiorri, J. B. Melin, L. Mendes, A. Mennella, S. Mitra, M. A. Miville Deschênes, A. Moneti, L. Montier, G. Morgante, D. Mortlock, D. Munshi, J. A. Murphy, P. Naselsky, F. Nati, P. Natoli, H. U. Nørgaard Nielsen, F. Noviello, D. Novikov, I. Novikov, S. Osborne, F. Pajot, D. Paoletti, F. Pasian, G. Patanchon, O. Perdereau, L. Perotto, F. Perrotta, F. Piacentini, M. Piat, E. Pierpaoli, R. Piffaretti, S. Plaszczynski, E. Pointecouteau, G. Polenta, N. Ponthieu, L. Popa, T. Poutanen, G. W. Pratt, S. Prunet, J. L. Puget, J. P. Rachen, W. T. Reach, R. Rebolo, M. Reinecke, M. Remazeilles, C. Renault, S. Ricciardi, T. Riller, I. Ristorcelli, G. Rocha, M. Roman, C. Rosset, M. Rossetti, J. A. Rubiño Martín, B. Rusholme, M. Sandri, G. Savini, D. Scott, G. F. Smoot, J. L. Starck, R. Sudiwala, R. Sunyaev, D. Sutton, A. S. Suur Uski, J. F. Sygnet, J. A. Tauber, L. Terenzi, L. Toffolatti, M. Tomasi, M. Tristram, J. Tuovinen, L. Valenziano, B. Van Tent, J. Varis, P. Vielva, F. Villa, N. Vittorio, L. A. Wade, B. D. Wandelt, N. Welikala, S. D. M. White, M. White, D. Yvon, A. Zacchei, A. Zonca, BORGANI, STEFANO, P. A. R., Ade, N., Aghanim, M., Arnaud, M., Ashdown, F., Atrio Barandela, J., Aumont, C., Baccigalupi, A., Balbi, A. J., Banday, R. B., Barreiro, J. G., Bartlett, E., Battaner, K., Benabed, A., Benoît, J. P., Bernard, M., Bersanelli, R., Bhatia, I., Bikmaev, J., Bobin, H., Böhringer, A., Bonaldi, J. R., Bond, Borgani, Stefano, J., Borrill, F. R., Bouchet, H., Bourdin, M. L., Brown, R., Burenin, C., Burigana, P., Cabella, J. F., Cardoso, P., Carvalho, G., Castex, A., Catalano, L., Cayón, A., Chamballu, L. Y., Chiang, G., Chon, P. R., Christensen, E., Churazov, D. L., Clement, S., Colafrancesco, S., Colombi, L. P. L., Colombo, B., Comi, A., Coulai, B. P., Crill, F., Cuttaia, A., Da Silva, H., Dahle, L., Danese, R. J., Davi, P., de Bernardi, G., de Gasperi, G., de Zotti, J., Delabrouille, J., Démoclè, F. X., Désert, J. M., Diego, K., Dolag, H., Dole, S., Donzelli, O., Doré, U., Dörl, M., Douspi, X., Dupac, G., Efstathiou, T. A., Enßlin, H. K., Eriksen, F., Finelli, I., Flores Cacho, O., Forni, P., Fosalba, M., Fraili, E., Franceschi, M., Frommert, S., Galeotta, K., Ganga, R. T., Génova Santo, M., Giard, Y., Giraud Héraud, J., González Nuevo, K. M., Górski, Gregorio, Anna, A., Gruppuso, F. K., Hansen, D., Harrison, A., Hempel, S., Henrot Versillé, C., Hernández Monteagudo, D., Herranz, S. R., Hildebrandt, E., Hivon, M., Hobson, W. A., Holme, G., Hurier, T. R., Jaffe, A. H., Jaffe, T., Jagemann, W. C., Jone, M., Juvela, E., Keihänen, I., Khamitov, T. S., Kisner, R., Kneissl, J., Knoche, L., Knox, M., Kunz, H., Kurki Suonio, G., Lagache, A., Lähteenmäki, J. M., Lamarre, A., Lasenby, C. R., Lawrence, M., Le Jeune, R., Leonardi, A., Liddle, P. B., Lilje, M., López Caniego, G., Luzzi, J. F., Macías Pérez, D., Maino, N., Mandolesi, M., Mari, F., Marleau, D. J., Marshall, E., Martínez González, S., Masi, M., Massardi, S., Matarrese, P., Mazzotta, S., Mei, A., Melchiorri, J. B., Melin, L., Mende, A., Mennella, S., Mitra, M. A., Miville Deschêne, A., Moneti, L., Montier, G., Morgante, D., Mortlock, D., Munshi, J. A., Murphy, P., Naselsky, F., Nati, P., Natoli, H. U., Nørgaard Nielsen, F., Noviello, D., Novikov, I., Novikov, S., Osborne, F., Pajot, D., Paoletti, F., Pasian, G., Patanchon, O., Perdereau, L., Perotto, F., Perrotta, F., Piacentini, M., Piat, E., Pierpaoli, R., Piffaretti, S., Plaszczynski, E., Pointecouteau, G., Polenta, N., Ponthieu, L., Popa, T., Poutanen, G. W., Pratt, S., Prunet, J. L., Puget, J. P., Rachen, W. T., Reach, R., Rebolo, M., Reinecke, M., Remazeille, C., Renault, S., Ricciardi, T., Riller, I., Ristorcelli, G., Rocha, M., Roman, C., Rosset, M., Rossetti, J. A., Rubiño Martín, B., Rusholme, M., Sandri, G., Savini, D., Scott, G. F., Smoot, J. L., Starck, R., Sudiwala, R., Sunyaev, D., Sutton, A. S., Suur Uski, J. F., Sygnet, J. A., Tauber, L., Terenzi, L., Toffolatti, M., Tomasi, M., Tristram, J., Tuovinen, L., Valenziano, B., Van Tent, J., Vari, P., Vielva, F., Villa, N., Vittorio, L. A., Wade, B. D., Wandelt, N., Welikala, S. D. M., White, M., White, D., Yvon, A., Zacchei, and A., Zonca
Subjects: galaxies: clusters: intracluster medium, clusters: intracluster medium [galaxies], galaxies: clusters: general, general [X-rays], cosmology: observations, clusters: general [galaxies], submillimeter: general, general [submillimeter], X-rays: general, errata, addenda, observation [cosmology]
Published: 2013

31. Symmetric Basal Ganglia lesion in a diabetic dialysis patient: recurrence and pathogenesis

Author: Pasquale F. Finelli
Subjects: Pathology, medicine.medical_specialty, medicine.medical_treatment, Case Reports, Pathogenesis, Lesion, Basal Ganglia Diseases, Recurrence, Renal Dialysis, Diabetes mellitus, Basal ganglia, medicine, Humans, Radiology, Nuclear Medicine and imaging, Basal ganglia disease, Dialysis, business.industry, General Medicine, Middle Aged, medicine.disease, Mr imaging, Diffusion Magnetic Resonance Imaging, Diabetes Mellitus, Type 2, Kidney Failure, Chronic, Female, Neurology (clinical), Hemodialysis, medicine.symptom, business
Abstract: Summary This paper describes a diabetic dialysis patient presenting two episodes of symmetric basal ganglia lesions occurring 18 months apart, and discusses the MR imaging findings and the pathogenesis of this condition.
Published: 2015

32. Nonaneurysmal Convexity Subarachnoid Hemorrhage

Author: Kalpesh C Patel and Pasquale F. Finelli
Subjects: Adult, Diagnostic Imaging, medicine.medical_specialty, Subarachnoid hemorrhage, Neurology, Radiography, Critical Care and Intensive Care Medicine, Magnetic resonance angiography, Aneurysm, Mesencephalon, Medical imaging, Humans, Medicine, cardiovascular diseases, Aged, Aged, 80 and over, medicine.diagnostic_test, business.industry, Middle Aged, Subarachnoid Hemorrhage, medicine.disease, nervous system diseases, body regions, Angiography, Etiology, Female, Neurology (clinical), Radiology, business
Abstract: Catheter angiography is performed to exclude aneurysm as the cause of subarachnoid hemorrhage (SAH). Certain categories of SAH however are for the most part nonaneurysmal and the risk of catheter angiography not justified. Primary convexity SAH may be nonaneurysmal and adequately investigated noninvasively. Determine if primary convexity SAH is nonaneurysmal in origin. Five new cases with primary convexity SAH and seven from the literature are reviewed for etiology, diagnostic studies, and outcome. Diagnostic investigations included catheter angiography in 6 patients, MR in 11 patients, computed tomography (CT) in 10 patients, magnetic resonance angiography/magnetic resonance venography in 7 patients, CT angiography in 1 patient, and outcome of the 12 patients was benign without subsequent hemorrhage. No case of primary convexity SAH was caused by aneurysm and outcome was benign in all patients, suggesting a noninvasive evaluation is adequate to investigate this condition.
Published: 2006

33. MR Imaging and Prognosis of Hypoxic-Ischemic Leukoencephalopathy

Author: Pasquale F. Finelli and Francis J. DiMario
Subjects: Adult, Male, medicine.medical_specialty, Pathology, Neurology, Adolescent, Critical Care and Intensive Care Medicine, Leukoencephalopathy, medicine, Humans, Dementia, Child, Hypoxic ischemic, medicine.diagnostic_test, business.industry, Dementia, Vascular, Magnetic resonance imaging, Prognosis, medicine.disease, Mr imaging, Diffusion Magnetic Resonance Imaging, Child, Preschool, Hypoxia-Ischemia, Brain, Female, Neurology (clinical), Radiology, Abnormality, business, Diffusion MRI
Abstract: To correlate prognosis of hypoxic-ischemic white-matter injury with magnetic resonance imaging (MRI). In a retrospective review at an urban medical center, three adult and three pediatric patients with predominant white-matter involvement caused by hypoxic-ischemic injury were evaluated over a 15-month period. Five patients with MRI-defined hypoxic-ischemic leukoencephalopathy had a favorable outcome, and one with associated diffusion-weighted abnormality of deep gray structures died. The prognosis of hypoxic-ischemic leukoencephalopathy is more favorable than previously reported, and diffusion-weighted imaging abnormality of deep gray structures was associated with a poor outcome.
Published: 2006

34. Fireblight in the Po valley (Italy): the monitoring programmes of Emilia-Romagna and Veneto regions1

Author: M. Vettorazzo, A. Saccardi, G. Zecchin, A. Calzolari, F. Finelli, and A. Contessi
Subjects: Geography, Environmental protection, law, Quarantine, Epidemic spread, Outbreak, Host plants, Plant Science, Horticulture, Socioeconomics, Agronomy and Crop Science, law.invention
Abstract: Erwinia amylovora, causing fireblight, is a very important quarantine pest for Italy. Since the beginning of the 1980s, import of host plants from countries where the disease occurs has been limited and subjected to laboratory analyses. Fireblight was found for the first time in Puglia (southern Italy) in 1990. Following this finding, a national monitoring network was set up in order to find new cases as rapidly as possible. In 1994, the first outbreaks of fireblight were found in Emilia-Romagna. In 1997, a severe epidemic spread throughout this region and the first cases were reported in the bordering regions Veneto and Lombardia. To face this new situation, additional specific local monitoring was set up. This article describes the operational and legislative measures taken in Emilia-Romagna and Veneto to contain the disease in orchards, to allow marketing of healthy plants for planting and to regulate the movement of beehives.
Published: 2004

35. Diagnostic Approach in Patients with Symmetric Imaging Lesions of the Deep Gray Nuclei

Author: Pasquale F. Finelli and Francis J. DiMario
Subjects: Adult, Male, Pathology, medicine.medical_specialty, Adolescent, Gray (unit), Lesion, Prosencephalon, Text mining, Humans, Medicine, In patient, Child, Aged, Brain Diseases, business.industry, Infant, Newborn, General Medicine, Middle Aged, Radiography, Etiology, Female, Neurology (clinical), Presentation (obstetrics), medicine.symptom, business
Abstract: Selective insult to brain deep gray matter nuclei is uncommon, may be congenital or acquired, acute or chronic, and varied in etiology. Determining the etiology relies on history, clinical presentation, laboratory investigations, and lesion pattern on Neuroimaging.We review the differential diagnosis and clinical, laboratory and neuroimaging pattern of conditions that manifest with lesions of deep gray matter nuclei in the context of representative case studies.While presentations may vary in individual patients, the essentials of history, clinical examination, laboratory evaluation,and neuroimaging lesion pattern can be efficiently directed to differentiate the various etiologies of deep gray matter nuclei lesions. In this review we focus on the etiologic classification and diagnostic approach to acute and chronic conditions that manifest on neuroimaging with bilateral symmetric lesions of deep gray matter nuclei.
Published: 2003

36. FIRE BLIGHT IN EMILIA-ROMAGNA (ITALY): SEARCHING POSSIBLE RELATIONSHIPS BETWEEN EPIDEMIC SPREAD, CLIMATE AND TERRITORY USING THE REGIONAL GEOGRAPHIC DATABASE AND GIS TECHNOLOGY

Author: A. Calzolari, G. Benedettini, G.L. Mazzoli, F. Finelli, R. Bugiani, M. Gherardi, and P. Govoni
Subjects: Geographic database, Geography, biology, business.industry, Fire blight, Epidemic spread, Environmental resource management, Forestry, Horticulture, biology.organism_classification, business
Published: 2002

37. The Etiology of Ring Lesions on Diffusion-Weighted Imaging

Author: Ethan B Foxman and Pasquale F. Finelli
Subjects: Adult, Male, Pathology, medicine.medical_specialty, Diagnosis, Differential, Immunocompromised Host, Young Adult, medicine, Demyelinating disease, Humans, Radiology, Nuclear Medicine and imaging, Brain abscess, Aged, Aged, 80 and over, business.industry, Multiple sclerosis, Progressive multifocal leukoencephalopathy, Brain, General Medicine, Original Articles, Middle Aged, medicine.disease, Diffusion Magnetic Resonance Imaging, Acute disseminated encephalomyelitis, Etiology, Encephalitis, Female, Neurology (clinical), Differential diagnosis, business, Demyelinating Diseases
Abstract: This study describes a series of cases and reviews the literature on cases of ring lesion on diffusion-weighted imaging to better appreciate the spectrum of disease associated with this neuroimaging finding. We retrospectively reviewed the MR studies of 15 patients with ring pattern lesions on diffusion-weighted imaging from an inpatient Neurology service of a tertiary care center seen over a ten-year period, and reviewed cases in the literature. Thirty-one cases, including 15 new patients, comprise the study group. Immunocompromised patients accounted for 38% of patients with ring lesions on diffusion-weighted imaging with cerebral aspergillosis in five patients, progressive multifocal leukoencephalopathy in three, primary CNS lymphoma in two, cerebral toxoplasmosis in one, and resolving cerebral hematoma in one. In the immunocompetent group demyelinating lesions including multiple sclerosis, acute disseminated encephalomyelitis, Balo's concentric sclerosis and acute necrotizing encephalitis, were seen in 11 patients, vascular etiology in four and neoplastic in three patients, two primary and one metastatic and pyogenic brain abscess in one. Ring lesions on diffusion-weighted imaging are associated with a spectrum of disease not previously considered. Immunocompromised patients accounted for almost one-half while demyelinating conditions in the immunocompetent patients were most common overall.
Published: 2014

38. Opinionspecial articles: Electronic media in neurology education: progress, promise, and pitfalls

Author: Pasquale F, Finelli
Subjects: Internet, Neurology, Teaching, Computer-Assisted Instruction, Forecasting
Published: 2014

39. Neurologic Manifestations of AIDS in Older Adults

Author: P. F. Finelli, J. W. Ross, and J. A. De Marcaida
Subjects: Microbiology (medical), Pediatrics, medicine.medical_specialty, Infectious Diseases, Acquired immunodeficiency syndrome (AIDS), business.industry, medicine, medicine.disease, business
Published: 1999

40. Neurological complications with acute sphenoid sinusitis a surgical emergency?

Author: Markos Poulopoulos and Pasquale F. Finelli
Subjects: Adult, Male, Emergency Medical Services, medicine.medical_specialty, Severe headache, Neurology, Critical Care and Intensive Care Medicine, Diagnosis, Differential, Pregnancy, otorhinolaryngologic diseases, medicine, Emergency medical services, Humans, Surgical emergency, Pregnancy Complications, Infectious, Sinus (anatomy), Headache diagnosis, Sphenoid Sinusitis, business.industry, Headache, Middle Aged, Surgery, medicine.anatomical_structure, Acute Disease, Drainage, Female, Neurology (clinical), Differential diagnosis, business
Abstract: Isolated acute sphenoid sinusitis is an uncommon sinus infection, frequently misdiagnosed and not usually considered in the differential diagnosis of acute severe headache, with the potential of serious neurologic complications.To describe two patients with acute sphenoid sinusitis who presented with acute onset of severe headache and consider the role of surgical management.Case report.Tertiary care hospital.Patient 1 developed right cavernous sinus thrombosis and permanent visual loss in one eye, requiring sphenoidotomy following failure of medical treatment. Patient 2 experienced failure of the medical treatment. However, sphenoidotomy abated all his symptoms without any neurologic sequelae.It is important to be aware of acute sphenoid sinusitis in the setting of new onset severe headache, when imaging studies are unrevealing for intracranial pathology. Considering the serious consequences of failed medical treatment vis-à-vis the safety and efficacy of sphenoidotomy we propose surgical intervention at the time of diagnosis.
Published: 2007

41. Swiss Cheese Striatum

Author: Pasquale F. Finelli
Subjects: medicine.medical_specialty, business.industry, MEDLINE, Virchow robin spaces, Striatum, Bioinformatics, Mr imaging, 03 medical and health sciences, 0302 clinical medicine, Text mining, medicine, Swiss cheese, Images in Clinical Neurology (E-Only), Medical physics, 030212 general & internal medicine, Neurology (clinical), Ct imaging, business, 030217 neurology & neurosurgery
Published: 2015

42. 166 TARGETED SEQUENCING ANALYSIS OF COMMONLY MUTATED GENES IN CHRONIC MYELOMONOCYTIC LEUKEMIA USING NGS: IMPACT AND CLINICAL IMPLICATIONS

Author: F. Torricelli, Erico Masala, A. Levis, M.E. Figueroa, A. Polloni, F. Finelli, A. Gozzini, Ana Valencia, Daniela Gioia, Emanuele Angelucci, Monia Lunghi, Bernardino Allione, Francesca Buchi, Alberto Bosi, Valeria Santini, E. Contini, Alessandro Sanna, Francesco Onida, and Omar Abdel-Wahab
Subjects: Genetics, Cancer Research, Oncology, medicine, Chronic myelomonocytic leukemia, Hematology, Biology, medicine.disease, Gene
Published: 2015

43. Differential Diagnosis of Restricted Diffusion of the Thalamus—Focus on Viral Encephalitis

Author: Pasquale F. Finelli and Christoph Stretz
Subjects: Focus (computing), business.industry, Viral encephalitis, Thalamus, medicine.disease, Bioinformatics, Text mining, Restricted Diffusion, medicine, Images in Clinical Neurology (E-Only), Neurology (clinical), Differential diagnosis, business, Neuroscience, Encephalitis, Diffusion MRI
Published: 2015

44. Primary lymphoma of CNS, mycophenolate mofetil and lupus

Author: A Prasad, J A DiGiuseppe, P F Finelli, and K Naik
Subjects: Adult, medicine.medical_specialty, Fatal outcome, Lymphoma, Lymphoproliferative disorders, 030204 cardiovascular system & hematology, Mycophenolate, Nephropathy, Central Nervous System Neoplasms, 03 medical and health sciences, Fatal Outcome, 0302 clinical medicine, Rheumatology, hemic and lymphatic diseases, medicine, Humans, Lupus Erythematosus, Systemic, Immunosuppression Therapy, 030203 arthritis & rheumatology, Lupus erythematosus, Systemic lupus erythematosus, business.industry, Mycophenolic Acid, medicine.disease, Dermatology, Diffusion Magnetic Resonance Imaging, Primary lymphoma, Female, business, Immunosuppressive Agents
Abstract: Lymphoproliferative disorders are known to complicate immunosuppressive therapy and two cases of primary lymphoma of CNS (PCNSL) have previously been described in association with mycophenolate mofetil (MMF) treatment. We report the third case of PCNSL in a patient with lupus nephropathy while on MMF treatment. PCNSL may be seen more frequently considering the increased use of MMF in immunosuppressant responsive conditions.
Published: 2006

45. Idiopathic granulomatous angiitis of the CNS manifesting as diffuse white matter disease

Author: Hilary Onyiuke, Dean F. Uphoff, and Pasquale F. Finelli
Subjects: Male, Vasculitis, Systemic disease, Pathology, medicine.medical_specialty, Biopsy, Neurological disorder, Diagnosis, Differential, White matter, medicine, Demyelinating disease, Humans, Granuloma, medicine.diagnostic_test, Vascular disease, business.industry, Leptomeninges, Brain biopsy, Brain, Middle Aged, medicine.disease, Magnetic Resonance Imaging, Cerebrovascular Disorders, medicine.anatomical_structure, Neurology (clinical), Tomography, X-Ray Computed, business
Abstract: A 48-year-old man presented with progressive spastic paraparesis and diffuse white matter involvement on neuroimaging that suggested a primary demyelinating disease. Brain biopsy 3 years after onset of symptoms demonstrated idiopathic granulomatous angiitis. In patients with MRI features of diffuse white matter disease of uncertain etiology, open brain biopsy of leptomeninges and parenchyma should be considered to exclude idiopathic granulomatous angiitis of the CNS.
Published: 1997

46. Target sign on enhanced MR imaging in toxoplasmosis

Author: Pasquale F, Finelli and Fatmah, Al Zahmi
Subjects: Acquired Immunodeficiency Syndrome, Toxoplasmosis, Cerebral, Humans, Tomography, X-Ray Computed, Magnetic Resonance Imaging
Published: 2013

47. Misdiagnosis of Treatable Stroke Mimic: The Case for HIV Screening in Practice Guidelines

Author: Pasquale F. Finelli
Subjects: Pediatrics, medicine.medical_specialty, education.field_of_study, Neurology, business.industry, Progressive multifocal leukoencephalopathy, Population, Stroke mimics, HIV screening, medicine.disease, Short Reports, Medicine, Neurology (clinical), Neurologic disease, business, Cost of care, education, Stroke
Abstract: Notably absent from current practice guidelines for common neurologic diseases as stroke and seizure is the revised Centers for Disease Control (CDC) recommendation for human immunodeficiency virus (HIV) testing of all clinical encounters. During a 9-month period 2 patients with treatable stroke mimics related to HIV type 1 infection were misdiagnosed resulting in delay in beginning antiretroviral therapy and increased cost and morbidity. This study was conducted to determine the frequency of HIV-1 screening in our stroke center population and consider the implications of such testing on neurologic disease. We surveyed our stroke center database to determine the frequency of HIV screening in ischemic strokes from January 2005 through May 2011. Of 2806 ischemic strokes, 27 (0.96%) patients were HIV-tested during the 6.5-year study period. We suggest that incorporating the CDC recommendations for HIV screening into neurology practice guidelines can impact diagnosis and treatment of unsuspected HIV-related neurologic disease with reduction in cost of care and morbidity.
Published: 2013

48. Autoimmune Limbic Encephalitis With GAD Antibodies

Author: Pasquale F. Finelli
Subjects: Pathology, medicine.medical_specialty, medicine.diagnostic_test, business.industry, Glutamate decarboxylase, Limbic encephalitis, Autoimmune limbic encephalitis, Magnetic resonance imaging, medicine.disease, Epilepsy, Neuroimmunology, nervous system, Short Reports, mental disorders, medicine, Neurology (clinical), business, Antibody screening, Neuroradiology
Abstract: The neurologic presentation of limbic encephalitis is variable and when it occurs due to a rare cause the diagnosis may be problematic. We present a case of autoimmune limbic encephalitis due to glutamic acid decarboxylase antibody and consider the magnetic resonance imaging and antineural antibody screening aspects in the diagnosis of this entity.
Published: 2013

49. A syndrome of bilateral symmetrical basal ganglia lesions in diabetic dialysis patients

Author: Pasquale F. Finelli and Joseph U. Singh
Subjects: medicine.medical_specialty, Pediatrics, medicine.medical_treatment, Context (language use), Basal Ganglia, Dysarthria, Renal Dialysis, Diabetes mellitus, Basal ganglia, medicine, Humans, Dialysis, medicine.diagnostic_test, business.industry, Magnetic resonance imaging, Syndrome, Middle Aged, medicine.disease, Gait, Pathophysiology, Surgery, Diabetes Mellitus, Type 2, Nephrology, Female, medicine.symptom, business
Abstract: A rare syndrome of acute symmetrical bilateral basal ganglia lesions in diabetic dialysis patients that manifests clinically with headache, dysarthria, and gait and movement disorder has been described almost exclusively in patients of Asian descent. The pathophysiology of this condition has not been established. Of the 28 cases reported, 3 patients have been from North America. In the context of magnetic resonance imaging showing dramatic resolution of lesions of the basal ganglia, this report describes a fourth case from North America of a 47-year-old Hispanic woman with diabetes on dialysis therapy who presented with headache, unsteady gait, and slurred speech. We also consider presymptomatic metabolic abnormalities in the pathogenesis of this disease.
Published: 2013

50. Limbic encephalitis as the presenting feature of Sjögren syndrome

Author: Pasquale F. Finelli and Violiza Inoa
Subjects: medicine.medical_specialty, Tonic pupil, Tandem gait, business.industry, Fluid-attenuated inversion recovery, Gait, Temporal lobe, Dysarthria, Physical medicine and rehabilitation, Cases, Gait Ataxia, Medicine, Intention tremor, Neurology (clinical), medicine.symptom, business
Abstract: A 27-year-old woman was transferred to our hospital for further evaluation of progressive gait difficulty, slurred speech, right hand tremor, and temporal lobe lesion. She was in her usual state of good health until 1 year earlier when she developed right hand weakness and tremor and slurred speech. Her symptoms gradually worsened over the next 6 months and significant dysarthria and right hand weakness and intention tremor was noted. Her penmanship was illegible, tandem gait was impaired, and rapid alternating movements with the right hand were slow compared to the left. A dilated left pupil was diagnosed as an Adie tonic pupil. MRI showed a small area of increased signal on fluid-attenuated inversion recovery (FLAIR) sequence in the right temporal lobe. She was readmitted because of falls, progressive cognitive impairment, gait ataxia, dysarthria, and right hand tremor. On gait testing, she could only walk with the assistance of 2 aides. Because of increased size of the right temporal lobe lesion on repeat MRI, she was transferred to our hospital for consideration of brain biopsy.
Published: 2013

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