1. Role of glucocorticoids in the regulation of bone marrow hemopoiesis in stress reaction
- Author
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Dygai Am, A. V. Mikhlenko, ED Goldberg, and Shakhov Vp
- Subjects
Male ,medicine.medical_specialty ,T-Lymphocytes ,medicine.medical_treatment ,Biology ,Mice ,Bone Marrow ,Precursor cell ,Internal medicine ,medicine ,Animals ,Antigens, Ly ,Glucocorticoids ,Pharmacology ,General Medicine ,Hematopoiesis ,Cell biology ,Mice, Inbred C57BL ,Steroid hormone ,Haematopoiesis ,medicine.anatomical_structure ,Endocrinology ,Lymphatic system ,Mice, Inbred CBA ,Bone marrow ,Myelopoiesis ,Stress, Psychological ,Glucocorticoid ,Homing (hematopoietic) ,medicine.drug - Abstract
We have studied the role played by glucocorticoids in the regulation of bone marrow hemopoiesis in stress reaction. The effector influence of the adrenal cortex hormones on the committed precursor cells of erythro-granulo-monocytopoiesis mediated through the T-cell system has been confirmed. Glucocorticosteroids initiate homing of the T-cell regulators of myelopoiesis of the Lyt-1+ phenotype from the lymphoid organs into the bone marrow.
- Published
- 1991
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