Search

Your search keyword '"Duff MO"' showing total 5 results
Start Over Author "Duff MO" Database OpenAIRE
5 results on '"Duff MO"'

1. Author Correction: Perspectives on ENCODE (Nature, (2020), 583, 7818, (693-698), 10.1038/s41586-020-2449-8)

Author

Abascal, FBC, Acosta, R, Addleman, NJ, Adrian, J, Afzal, V, Aken, B, Ai, R, Akiyama, JA, Jammal, OA, Amrhein, H, Anderson, SM, Dileep, V, Ding, B, Djebali, S, Dobin, A, Dominguez, D, Donaldson, S, Drenkow, J, Dreszer, TR, Snyder, MP, Drier, Y, Duff, MO, Dunn, D, Sisu, C, Eastman, C, Ecker, JR, Edwards, MD, El-Ali, N, Andrews, GR, Antoshechkin, I, Ardlie, KG, Armstrong, J, Astley, M, Banerjee, B, Barkal, AA, Barnes, IHA, Barozzi, I, Barrell, D, Barson, G, Bates, D, Baymuradov, UK, Bazile, C, Beer, MA, Beik, S, Bender, MA, Bennett, R, Bouvrette, LPB, Bernstein, BE, Berry, A, Bhaskar, A, Bignell, A, Blue, SM, Bodine, DM, Boix, C, Boley, N, Borrman, T, Borsari, B, Boyle, AP, Brandsmeier, LA, Breschi, A, Bresnick, EH, Brooks, JA, Buckley, M, Burge, CB, Byron, R, Cahill, E, Cai, L, Cao, L, Carty, M, Castanon, RG, Castillo, A, Chaib, H, Chan, ET, Chee, DR, Chee, S, Chen, H, Chen, JY, Chen, S, Cherry, JM, Chhetri, SB, Choudhary, JS, Chrast, J, Chung, D, Clarke, D, Cody, NAL, Coppola, CJ, Coursen, J, D’Ippolito, AM, Dalton, S, Danyko, C, Davidson, C, Davila-Velderrain, J, Davis, CA, Dekker, J, Deran, A, DeSalvo, G, Despacio-Reyes, G, Dewey, CN, Dickel, DE, Diegel, M, Diekhans, M, and The ENCODE Project Consortium

Abstract

The Original Article (https://doi.org/10.1038/s41586-020-2449-8) was published on 29 July 2020. Copyright © The Authors 2022. In this Article, the authors Rizi Ai (Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA, USA) and Shantao Li (Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA) were mistakenly omitted from the ENCODE Project Consortium author list. The original Article has been corrected online.

Published
2022

2. Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes

Author

Moore, JE, Abascal, F, Acosta, R, Addleman, NJ, Adrian, J, Afzal, V, Aken, B, Akiyama, JA, Jammal, OA, Amrhein, H, Anderson, SM, Edwards, MD, El-Ali, N, Elhajjajy, SI, Andrews, GR, Antoshechkin, I, Ardlie, KG, Armstrong, J, Astley, M, Banerjee, B, Barkal, AA, Barnes, IHA, Barozzi, I, Barrell, D, Barson, G, Bates, D, Baymuradov, UK, Bazile, C, Beer, MA, Beik, S, Bender, MA, Bennett, R, Bouvrette, LPB, Bernstein, BE, Berry, A, Bhaskar, A, Bignell, A, Blue, SM, Bodine, DM, Boix, C, Boley, N, Borrman, T, Borsari, B, Boyle, AP, Brandsmeier, LA, Breschi, A, Bresnick, EH, Brooks, JA, Buckley, M, Burge, CB, Byron, R, Cahill, E, Cai, L, Cao, L, Carty, M, Castanon, RG, Castillo, A, Chaib, H, Chan, ET, Chee, DR, Chee, S, Chen, H, Chen, JY, Chen, S, Cherry, JM, Chhetri, SB, Choudhary, JS, Chrast, J, Chung, D, Clarke, D, Cody, NAL, Coppola, CJ, Coursen, J, D’Ippolito, AM, Dalton, S, Danyko, C, Davidson, C, Davila-Velderrain, J, Davis, CA, Dekker, J, Deran, A, DeSalvo, G, Despacio-Reyes, G, Dewey, CN, Dickel, DE, Diegel, M, Diekhans, M, Dileep, V, Ding, B, Djebali, S, Dobin, A, Dominguez, D, Donaldson, S, Drenkow, J, Dreszer, TR, Drier, Y, Duff, MO, Dunn, D, Eastman, C, Ecker, JR, and The ENCODE Project Consortium

Subjects
Multidisciplinary, epigenomics, data integration, functional genomics
Abstract

Online Correction for: https://doi.org/10.1038/s41586-020-2493-4 | Erratum for https://bura.brunel.ac.uk/handle/2438/21299 In the version of this article initially published, two members of the ENCODE Project Consortium were missing from the author list. Rizi Ai (Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA, USA) and Shantao Li (Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA) are now included in the author list. These errors have been corrected in the online version of the article : 'Expanded encyclopaedias of DNA elements in the human and mouse genomes'. https://www.nature.com/articles/s41586-021-04226-3 https://www.nature.com/articles/s41586-021-04226-3

Published
2022
Full Text
View/download PDF

3. Perspectives on ENCODE

Author

Snyder, MP, Gingeras, TR, Abascal, F, Acosta, R, Addleman, NJ, Adrian, J, Afzal, V, Aken, B, Akiyama, JA, Jammal, OA, Amrhein, H, Dileep, V, Ding, B, Djebali, S, Dobin, A, Dominguez, D, Sisu, C, Donaldson, S, Drenkow, J, Dreszer, TR, Drier, Y, Duff, MO, Dunn, D, Anderson, SM, Andrews, GR, Eastman, C, Ecker, JR, Edwards, MD, El-Ali, N, Elhajjajy, SI, Antoshechkin, I, Ardlie, KG, Armstrong, J, Astley, M, Banerjee, B, Barkal, AA, Barnes, IHA, Barozzi, I, Barrell, D, Barson, G, Bates, D, Baymuradov, UK, Bazile, C, Beer, MA, Beik, S, Bender, MA, Bennett, R, Bouvrette, LPB, Bernstein, BE, Berry, A, Bhaskar, A, Bignell, A, Blue, SM, Bodine, DM, Boix, C, Boley, N, Borrman, T, Borsari, B, Boyle, AP, Brandsmeier, LA, Breschi, A, Bresnick, EH, Brooks, JA, Buckley, M, Burge, CB, Byron, R, Cahill, E, Cai, L, Cao, L, Carty, M, Castanon, RG, Castillo, A, Chaib, H, Chan, ET, Chee, DR, Chee, S, Chen, H, Chen, JY, Chen, S, Cherry, JM, Chhetri, SB, Choudhary, JS, Chrast, J, Chung, D, Clarke, D, Cody, NAL, Coppola, CJ, Coursen, J, D’Ippolito, AM, Dalton, S, Danyko, C, Davidson, C, Davila-Velderrain, J, Davis, CA, Dekker, J, Deran, A, DeSalvo, G, Despacio-Reyes, G, Dewey, CN, Dickel, DE, Diegel, M, Diekhans, M, and The ENCODE Project Consortium

Subjects
Epigenomics, Quality Control, 610 Medicine & health, Computational biology, Biology, Regulatory Sequences, Nucleic Acid, ENCODE, Genome, Histones, 03 medical and health sciences, transcriptomics, Mice, 0302 clinical medicine, Databases, Genetic, Animals, Humans, Transcriptomics, Gene, genome, 030304 developmental biology, Regulation of gene expression, 0303 health sciences, Multidisciplinary, Binding Sites, Genome, Human, Molecular Sequence Annotation, Genomics, DNA Methylation, Chromatin, DNA binding site, Gene Expression Regulation, 030220 oncology & carcinogenesis, Perspective, epigenomics, Human genome, Epigenetics, epigenetic, Transcription Factors
Abstract

The Encylopedia of DNA Elements (ENCODE) Project launched in 2003 with the long-term goal of developing a comprehensive map of functional elements in the human genome. These included genes, biochemical regions associated with gene regulation (for example, transcription factor binding sites, open chromatin, and histone marks) and transcript isoforms. The marks serve as sites for candidate cis-regulatory elements (cCREs) that may serve functional roles in regulating gene expression1. The project has been extended to model organisms, particularly the mouse. In the third phase of ENCODE, nearly a million and more than 300,000 cCRE annotations have been generated for human and mouse, respectively, and these have provided a valuable resource for the scientific community., The authors summarize the history of the ENCODE Project, the achievements of ENCODE 1 and ENCODE 2, and how the new data generated and analysed in ENCODE 3 complement the previous phases.

Published
2019
Full Text
View/download PDF

4. Regulation of alternative splicing in Drosophila by 56 RNA binding proteins

Author

Brooks, AN, Duff, MO, May, G, Yang, L, Bolisetty, M, Landolin, J, Wan, K, Sandler, J, Booth, BW, Celniker, SE, Graveley, BR, and Brenner, SE

Subjects
TATA-Binding Protein Associated Factors, Bioinformatics, 1.1 Normal biological development and functioning, Human Genome, RNA-Binding Proteins, Exons, Biological Sciences, Medical and Health Sciences, Heterogeneous-Nuclear Ribonucleoproteins, Alternative Splicing, Underpinning research, RNA Precursors, Genetics, Animals, Drosophila Proteins, RNA, Drosophila, RNA Interference, Generic health relevance, Sequence Analysis
Abstract

© 2015 Brooks et al. Alternative splicing is regulated by RNA binding proteins (RBPs) that recognize pre-mRNA sequence elements and activate or repress adjacent exons. Here, we used RNA interference and RNA-seq to identify splicing events regulated by 56 Drosophila proteins, some previously unknown to regulate splicing. Nearly all proteins affected alternative first exons, suggesting that RBPs play important roles in first exon choice. Half of the splicing events were regulated by multiple proteins, demonstrating extensive combinatorial regulation. We observed that SR and hnRNP proteins tend to act coordinately with each other, not antagonistically. We also identified a cross-regulatory network where splicing regulators affected the splicing of pre-mRNAs encoding other splicing regulators. This large-scale study substantially enhances our understanding of recent models of splicing regulation and provides a resource of thousands of exons that are regulated by 56 diverse RBPs.

Published
2015
Full Text
View/download PDF

5. Comparative analysis of the transcriptome across distant species

Author

Gerstein, MB, Rozowsky, J, Yan, KK, Wang, D, Cheng, C, Brown, JB, Davis, CA, Hillier, L, Sisu, C, Li, JJ, Pei, B, Harmanci, AO, Duff, MO, Djebali, S, Alexander, RP, Alver, BH, Auerbach, R, Bell, K, Bickel, PJ, Boeck, ME, Boley, NP, Booth, BW, Cherbas, L, Cherbas, P, Di, C, Dobin, A, Drenkow, J, Ewing, B, Fang, G, Fastuca, M, Feingold, EA, Frankish, A, Gao, G, Good, PJ, Guigó, R, Hammonds, A, Harrow, J, Hoskins, RA, Howald, C, Hu, L, Huang, H, Hubbard, TJP, Huynh, C, Jha, S, Kasper, D, Kato, M, Kaufman, TC, Kitchen, RR, Ladewig, E, Lagarde, J, Lai, E, Leng, J, Lu, Z, MacCoss, M, May, G, McWhirter, R, Merrihew, G, Miller, DM, Mortazavi, A, Murad, R, Oliver, B, Olson, S, Park, PJ, Pazin, MJ, Perrimon, N, Pervouchine, D, Reinke, V, Reymond, A, and Robinson, G

Subjects
animal structures, fungi
Abstract

The transcriptome is the readout of the genome. Identifying common features in it across distant species can reveal fundamental principles. To this end, the ENCODE and modENCODE consortia have generated large amounts of matched RNA-sequencing data for human, worm and fly. Uniform processing and comprehensive annotation of these data allow comparison across metazoan phyla, extending beyond earlier within-phylum transcriptome comparisons and revealing ancient, conserved features. Specifically, we discover co-expression modules shared across animals, many of which are enriched in developmental genes. Moreover, we use expression patterns to align the stages in worm and fly development and find a novel pairing between worm embryo and fly pupae, in addition to the embryo-to-embryo and larvae-to-larvae pairings. Furthermore, we find that the extent of non-canonical, non-coding transcription is similar in each organism, per base pair. Finally, we find in all three organisms that the gene-expression levels, both coding and non-coding, can be quantitatively predicted from chromatin features at the promoter using a â universal model' based on a single set of organism-independent parameters. © 2014 Macmillan Publishers Limited.

Published
2014
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results