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A general framework for future genomic data libraries, where individual details are protected while remaining open to investigators, is grounded on two new concepts: i) the genomic data is split into parts whose information content is low enough not to put at stake confidentiality and integrity. Data does not need to be encrypted.ii) management of the bank is organized along a blockchain scheme that would permit free access and permanent control on the traffic of information between the bank and the investigators.

A correlation function that compares each base in a DNA sequence to its various neighbours and which is subsequently processed by Fourier and wavelet transforms has been developed. The procedure has been applied to sequences from the human chromosome 22, to nef genes from various HIV clones and to myosin heavy chain DNA. It permits to readily visualize regular features in DNA which are related to the stability of heteroduplexes formed upon strand slippage.