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1. Euclid preparation : XX. The Complete Calibration of the Color-Redshift Relation survey: LBT observations and data release

Author

Euclid Collaboration, Saglia, R., De Nicola, S., Fabricius, M., Guglielmo, V., Snigula, J., Zöller, R., Bender, R., Heidt, J., Masters, D., Stern, D., Paltani, S., Amara, A., Auricchio, N., Baldi, M., Bodendorf, C., Bonino, D., Branchini, E., Brescia, M., Brinchmann, J., Camera, S., Capobianco, V., Carbone, C., Carretero, J., Castellano, M., Cavuoti, S., Cledassou, R., Congedo, G., Conselice, C. J., Conversi, L., Copin, Y., Corcione, L., Courbin, F., Cropper, M., Da Silva, A., Degaudenzi, H., Douspis, M., Dubath, F., Duncan, C. A. J., Dupac, X., Dusini, S., Farrens, S., Frailis, M., Franceschi, E., Galeotta, S., Garilli, B., Gillard, W., Gillis, B., Giocoli, C., Grazian, A., Grupp, F., Haugan, S. V. H., Hoekstra, H., Holmes, W., Hormuth, F., Hornstrup, A., Jahnke, K., Kümmel, M., Kermiche, S., Kiessling, A., Kunz, M., Kurki-Suonio, H., Laureijs, R., Ligori, S., Lilje, P. B., Lloro, I., Maiorano, E., Marggraf, O., Markovic, K., Marulli, F., Massey, R., McCracken, H. J., Melchior, M., Meylan, G., Moresco, M., Moscardini, L., Munari, E., Niemi, S. M., Padilla, C., Pasian, F., Pedersen, K., Percival, W. J., Pettorino, V., Pires, S., Poncet, M., Popa, L., Pozzetti, L., Raison, F., Renzi, A., Rhodes, J., Riccio, G., Romelli, E., Rossetti, E., Sapone, D., Sartoris, B., Schneider, P., Secroun, A., Seidel, G., Sirignano, C., Sirri, G., Stanco, L., Tallada-Crespí, P., Tavagnacco, D., Taylor, A. N., Tereno, I., Toledo-Moreo, R., Torradeflot, F., Tutusaus, I., Valentijn, E. A., Valenziano, L., Vassallo, T., Wang, Y., Zacchei, A., Zamorani, G., Zoubian, J., Andreon, S., Bardelli, S., Graciá-Carpio, J., Maino, D., Mauri, N., Tramacere, A., Zucca, E., Ayllon, A. Alvarez, Aussel, H., Baccigalupi, C., Balaguera-Antolínez, A., Ballardini, M., Biviano, A., Bolzonella, M., Bozzo, E., Burigana, C., Cabanac, R., Cappi, A., Carvalho, C. S., Casas, S., Castignani, G., Cooray, A., Coupon, J., Courtois, H. M., Davini, S., Desprez, G., Dole, H., Escartin, J. A., Escoffier, S., Farina, M., Fotopoulou, S., Ganga, K., Garcia-Bellido, J., George, K., Giacomini, F., Gozaliasl, G., Hildebrandt, H., Hook, I., Ilbert, O., Kansal, V., Kashlinsky, A., Keihanen, E., Kirkpatrick, C. C., Loureiro, A., Macías-Pérez, J., Magliocchetti, M., Mainetti, G., Maoli, R., Martinelli, M., Martinet, N., Metcalf, R. B., Morgante, G., Nadathur, S., Nucita, A. A., Patrizii, L., Popa, V., Porciani, C., Potter, D., Pourtsidou, A., Reimberg, P., Sánchez, A. G., Sakr, Z., Schirmer, M., Sefusatti, E., Sereno, M., Stadel, J., Teyssier, R., Valieri, C., Valiviita, J., Veropalumbo, A., Viel, M., Department of Physics, Research Program in Systems Oncology, Helsinki Institute of Physics, Saglia, R., De Nicola, S., Fabricius, M., Guglielmo, V., Snigula, J., Z??ller, R., Bender, R., Heidt, J., Masters, D., Stern, D., Paltani, S., Amara, A., Auricchio, N., Baldi, M., Bodendorf, C., Bonino, D., Branchini, E., Brescia, M., Brinchmann, J., Camera, S., Capobianco, V., Carbone, C., Carretero, J., Castellano, M., Cavuoti, S., Cledassou, R., Congedo, G., Conselice, C. J., Conversi, L., Copin, Y., Corcione, L., Courbin, F., Cropper, M., Da Silva, A., Degaudenzi, H., Douspis, M., Dubath, F., Duncan, C. A. J., Dupac, X., Dusini, S., Farrens, S., Frailis, M., Franceschi, E., Galeotta, S., Garilli, B., Gillard, W., Gillis, B., Giocoli, C., Grazian, A., Grupp, F., Haugan, S. V. H., Hoekstra, H., Holmes, W., Hormuth, F., Hornstrup, A., Jahnke, K., K??mmel, M., Kermiche, S., Kiessling, A., Kunz, M., Kurki-Suonio, H., Laureijs, R., Ligori, S., Lilje, P. B., Lloro, I., Maiorano, E., Marggraf, O., Markovic, K., Marulli, F., Massey, R., Mccracken, H. J., Melchior, M., Meylan, G., Moresco, M., Moscardini, L., Munari, E., Niemi, S. M., Padilla, C., Pasian, F., Pedersen, K., Percival, W. J., Pettorino, V., Pires, S., Poncet, M., Popa, L., Pozzetti, L., Raison, F., Renzi, A., Rhodes, J., Riccio, G., Romelli, E., Rossetti, E., Sapone, D., Sartoris, B., Schneider, P., Secroun, A., Seidel, G., Sirignano, C., Sirri, G., Stanco, L., Tallada-Cresp??, P., Tavagnacco, D., Taylor, A. N., Tereno, I., Toledo-Moreo, R., Torradeflot, F., Tutusaus, I., Valentijn, E. A., Valenziano, L., Vassallo, T., Wang, Y., Zacchei, A., Zamorani, G., Zoubian, J., Andreon, S., Bardelli, S., Graci??-Carpio, J., Maino, D., Mauri, N., Tramacere, A., Zucca, E., Alvarez Ayllon, A., Aussel, H., Baccigalupi, C., Balaguera-Antol??nez, A., Ballardini, M., Biviano, A., Bolzonella, M., Bozzo, E., Burigana, C., Cabanac, R., Cappi, A., Carvalho, C. S., Casas, S., Castignani, G., Cooray, A., Coupon, J., Courtois, H. M., Davini, S., Desprez, G., Dole, H., Escartin, J. A., Escoffier, S., Farina, M., Fotopoulou, S., Ganga, K., Garcia-Bellido, J., George, K., Giacomini, F., Gozaliasl, G., Hildebrandt, H., Hook, I., Ilbert, O., Kansal, V., Kashlinsky, A., Keihanen, E., Kirkpatrick, C. C., Loureiro, A., Mac??as-P??rez, J., Magliocchetti, M., Mainetti, G., Maoli, R., Martinelli, M., Martinet, N., Metcalf, R. B., Morgante, G., Nadathur, S., Nucita, A. A., Patrizii, L., Popa, V., Porciani, C., Potter, D., Pourtsidou, A., Reimberg, P., S??nchez, A. G., Sakr, Z., Schirmer, M., Sefusatti, E., Sereno, M., Stadel, J., Teyssier, R., Valieri, C., Valiviita, J., Veropalumbo, A., Viel, M., Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Astrophysique de Marseille (LAM), Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS), Euclid, Intelligent Systems, Astronomy, R. Saglia, S. De Nicola, M. Fabriciu, V. Guglielmo, J. Snigula, R. Zöller, R. Bender, J. Heidt, D. Master, D. Stern, S. Paltani, A. Amara, N. Auricchio, M. Baldi, C. Bodendorf, D. Bonino, E. Branchini, M. Brescia, J. Brinchmann, S. Camera, V. Capobianco, C. Carbone, J. Carretero, M. Castellano, S. Cavuoti, R. Cledassou, G. Congedo, C. J. Conselice, L. Conversi, Y. Copin, L. Corcione, F. Courbin, M. Cropper, A. Da Silva, H. Degaudenzi, M. Douspi, F. Dubath, C. A. J. Duncan, X. Dupac, S. Dusini, S. Farren, M. Fraili, E. Franceschi, S. Galeotta, B. Garilli, W. Gillard, B. Gilli, C. Giocoli, A. Grazian, F. Grupp, S. V. H. Haugan, H. Hoekstra, W. Holme, F. Hormuth, A. Hornstrup, K. Jahnke, M. Kümmel, S. Kermiche, A. Kiessling, M. Kunz, H. Kurki-Suonio, R. Laureij, S. Ligori, P. B. Lilje, I. Lloro, E. Maiorano, O. Marggraf, K. Markovic, F. Marulli, R. Massey, H. J. McCracken, M. Melchior, G. Meylan, M. Moresco, L. Moscardini, E. Munari, S. M. Niemi, C. Padilla, F. Pasian, K. Pedersen, W. J. Percival, V. Pettorino, S. Pire, M. Poncet, L. Popa, L. Pozzetti, F. Raison, A. Renzi, J. Rhode, G. Riccio, E. Romelli, E. Rossetti, D. Sapone, B. Sartori, P. Schneider, A. Secroun, G. Seidel, C. Sirignano, G. Sirri, L. Stanco, P. Tallada-Crespí, D. Tavagnacco, A. N. Taylor, I. Tereno, R. Toledo-Moreo, F. Torradeflot, I. Tutusau, E. A. Valentijn, L. Valenziano, T. Vassallo, Y. Wang, A. Zacchei, G. Zamorani, J. Zoubian, S. Andreon, S. Bardelli, J. Graciá-Carpio, D. Maino, N. Mauri, A. Tramacere, E. Zucca, A. Alvarez Ayllon, H. Aussel, C. Baccigalupi, A. Balaguera-Antolínez, M. Ballardini, A. Biviano, M. Bolzonella, E. Bozzo, C. Burigana, R. Cabanac, A. Cappi, C. S. Carvalho, S. Casa, G. Castignani, A. Cooray, J. Coupon, H. M. Courtoi, S. Davini, G. Desprez, H. Dole, J. A. Escartin, S. Escoffier, M. Farina, S. Fotopoulou, K. Ganga, J. Garcia-Bellido, K. George, F. Giacomini, G. Gozaliasl, H. Hildebrandt, I. Hook, O. Ilbert, V. Kansal, A. Kashlinsky, E. Keihanen, C. C. Kirkpatrick, A. Loureiro, J. Macías-Pérez, M. Magliocchetti, G. Mainetti, R. Maoli, M. Martinelli, N. Martinet, R. B. Metcalf, G. Morgante, S. Nadathur, A. A. Nucita, L. Patrizii, V. Popa, C. Porciani, D. Potter, A. Pourtsidou, P. Reimberg, A. G. Sánchez, Z. Sakr, M. Schirmer, E. Sefusatti, M. Sereno, J. Stadel, R. Teyssier, C. Valieri, J. Valiviita, A. Veropalumbo, M. Viel, Zöller, R., Kümmel, M., Tallada-Crespí, P., Graciá-Carpio, J., Balaguera-Antolínez, A., Macías-Pérez, J., and Sánchez, A. G.

Subjects
Cosmology and Nongalactic Astrophysics (astro-ph.CO), catalogs, Galaxies: distances and redshifts, surveys, Astrophysics - cosmology and nongalactic astrophysics, Astrophysics::Instrumentation and Methods for Astrophysics, Euclid, FOS: Physical sciences, Galaxies - distances and redshifts, Astronomy and Astrophysics, cosmos, Astrophysics::Cosmology and Extragalactic Astrophysics, Surveys, 115 Astronomy, Space science, Cosmology, deep imaging survey, Space and Planetary Science, distances and redshifts, catalogs, surveys [galaxies], distances and redshifts [Galaxies], galaxies: distances and redshifts, Catalogs, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], Astrophysics::Galaxy Astrophysics
Abstract

The Complete Calibration of the Color-Redshift Relation survey (C3R2) is a spectroscopic programme designed to empirically calibrate the galaxy color-redshift relation to the Euclid depth (I_E=24.5), a key ingredient for the success of Stage IV dark energy projects based on weak lensing cosmology. A spectroscopic calibration sample as representative as possible of the galaxies in the Euclid weak lensing sample is being collected, selecting galaxies from a self-organizing map (SOM) representation of the galaxy color space. Here, we present the results of a near-infrared H- and K-bands spectroscopic campaign carried out using the LUCI instruments at the LBT. For a total of 251 galaxies, we present new highly-reliable redshifts in the 1.3, A&A language edited version

Published
2022
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3. Euclid preparation, XX. The Complete Calibration of the Color–Redshift Relation survey: LBT observations and data release

Author

Euclid Collaboration, Saglia, R., De Nicola, S., Fabricius, M., Guglielmo, V., Snigula, J., Zöller, R., Bender, R., Heidt, J., Masters, D., Stern, D., Paltani, S., Amara, A., Auricchio, N., Baldi, M., Bodendorf, C., Bonino, D., Branchini, E., Brescia, M., Brinchmann, J., Camera, S., Capobianco, V., Carbone, C., Carretero, J., Castellano, M., Cavuoti, S., Cledassou, R., Congedo, G., Conselice, C. J., Conversi, L., Copin, Y., Corcione, L., Courbin, F., Cropper, M., Da Silva, A., Degaudenzi, H., Douspis, M., Dubath, F., Duncan, C. A. J., Dupac, X., Dusini, S., Farrens, S., Frailis, M., Franceschi, E., Galeotta, S., Garilli, B., Gillard, W., Gillis, B., Giocoli, C., Grazian, A., Grupp, F., Haugan, S. V. H., Hoekstra, H., Holmes, W., Hormuth, F., Hornstrup, A., Jahnke, K., Kümmel, M., Kermiche, S., Kiessling, A., Kunz, M., Kurki-Suonio, H., Laureijs, R., Ligori, S., Lilje, P. B., Lloro, I., Maiorano, E., Marggraf, O., Markovic, K., Marulli, F., Massey, R., McCracken, H. J., Melchior, M., Meylan, G., Moresco, M., Moscardini, L., Munari, E., Niemi, S. M., Padilla, C., Pasian, F., Pedersen, K., Percival, W. J., Pettorino, V., Pires, S., Poncet, M., Popa, L., Pozzetti, L., Raison, F., Renzi, A., Rhodes, J., Riccio, G., Romelli, E., Rossetti, E., Sapone, D., Sartoris, B., Schneider, P., Secroun, A., Seidel, G., Sirignano, C., Sirri, G., Stanco, L., Tallada-Crespí, P., Tavagnacco, D., Taylor, A. N., Tereno, I., Toledo-Moreo, R., Torradeflot, F., Tutusaus, I., Valentijn, E. A., Valenziano, L., Vassallo, T., Wang, Y., Zacchei, A., Zamorani, G., Zoubian, J., Andreon, S., Bardelli, S., Graciá-Carpio, J., Maino, D., Mauri, N., Tramacere, A., Zucca, E., Alvarez Ayllon, A., Aussel, H., Baccigalupi, C., Balaguera-Antolínez, A., Ballardini, M., Biviano, A., Bolzonella, M., Bozzo, E., Burigana, C., Cabanac, R., Cappi, A., Carvalho, C. S., Casas, Santiago, Castignani, G., Cooray, A., Coupon, J., Courtois, H. M., Davini, S., Desprez, G., Dole, H., Escartin, J. A., Escoffier, S., Farina, M., Fotopoulou, S., Ganga, K., Garcia-Bellido, J., George, K., Giacomini, F., Gozaliasl, G., Hildebrandt, H., Hook, I., Ilbert, O., Kansal, V., Kashlinsky, A., Keihanen, E., Kirkpatrick, C. C., Loureiro, A., Macías-Pérez, J., Magliocchetti, M., Mainetti, G., Maoli, R., Martinelli, M., Martinet, N., Metcalf, R. B., Morgante, G., Nadathur, S., Nucita, A. A., Patrizii, L., Popa, V., Porciani, C., Potter, D., Pourtsidou, A., Reimberg, P., Sánchez, A. G., Sakr, Z., Schirmer, M., Sefusatti, E., Sereno, M., Stadel, J., Teyssier, R., Valieri, C., Valiviita, J., Veropalumbo, A., and Viel, M.

Abstract

22 Seiten (2022).

Published
2022
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4. High rates of sustained virological response despite premature discontinuation of directly acting antivirals in HCV-infected patients treated in a real-life setting

Author

Fabbiani M., Lombardi A., Colaneri M., Del Poggio P., Perini P., D'Ambrosio R., Degasperi E., Dibenedetto C., Giorgini A., Pasulo L., Maggiolo F., Castelli F., Brambilla P., Spinelli O., Re T., Lleo A., Rumi M., Uberti-Foppa C., Soria A., Aghemo A., Lampertico P., Baiguera C., Schiavini M., Fagiuoli S., Bruno R., Borghi M., Soffredini R., Perbellini R., Gori A., Ferroni V., Colpani M., Manini M., Cologni G., Lazzaroni S., Vinci M., De Nicola S., Mazzarelli C., Angelini Zucchetti T., Picciotto V., Puoti M., Rossotti R., Landonio S., Magni C. F., Rizzardini G., Colella E., Columpsi P., Gambaro A., Spolti A., Magnani C., Vigano P., Mena M., Villa M., Caramma I., Basilico C., Capelli F., Biagiotti S., Mazzone A., Saladino V., Baldacci M. P., Gatti F., Varalli L., Morini L., Menzaghi B., Farinazzo M., Meli R., Plaz Torres M. C., Fanetti I., Orellana D., Zermiani P., Zuin M., De Bona A., D'Arminio Monforte A., Capretti A., Taddei M. T., Soncini M., Spinetti A., Zaltron S., Pigozzi M. G., Rossini A., Pan A., Dal Zoppo S., Zoncada A., Memoli M., Salpietro S., Hamid H., Messina E., Colombo A. E., Giglio O., Bonfanti P., Molteni C., Terreni N., Spinzi G., Conforti S., Clerici E., Menozzi F., Buscarini E., Centenaro R., Corbellini A., Noventa F., Gritti S., Giani P., Fabbiani, Massimiliano, Lombardi, Andrea, Colaneri, Marta, Del Poggio, Paolo, Perini, Paolo, D'Ambrosio, Roberta, Degasperi, Elisabetta, Dibenedetto, Clara, Giorgini, Alessia, Pasulo, Luisa, Maggiolo, Franco, Castelli, Francesco, Brambilla, Paola, Spinelli, Ombretta, Tiziana, Re, Lleo, Ana, Rumi, Mariagrazia, Uberti-Foppa, Caterina, Soria, Alessandro, Aghemo, Alessio, Lampertico, Pietro, Baiguera, Chiara, Schiavini, Monica, Fagiuoli, Stefano, Bruno, Raffaele, Fabbiani, M, Lombardi, A, Colaneri, M, Del Poggio, P, Perini, P, D'Ambrosio, R, Degasperi, E, Dibenedetto, C, Giorgini, A, Pasulo, L, Maggiolo, F, Castelli, F, Brambilla, P, Spinelli, O, Re, T, Lleo, A, Rumi, M, Uberti-Foppa, C, Soria, A, Aghemo, A, Lampertico, P, Baiguera, C, Schiavini, M, Fagiuoli, S, Bruno, R, Borghi, M, Soffredini, R, Perbellini, R, Gori, A, Ferroni, V, Colpani, M, Manini, M, Cologni, G, Lazzaroni, S, Vinci, M, De Nicola, S, Mazzarelli, C, Angelini Zucchetti, T, Picciotto, V, Puoti, M, Rossotti, R, Landonio, S, Magni, C, Rizzardini, G, Colella, E, Columpsi, P, Gambaro, A, Spolti, A, Magnani, C, Vigano, P, Mena, M, Villa, M, Caramma, I, Basilico, C, Capelli, F, Biagiotti, S, Mazzone, A, Saladino, V, Baldacci, M, Gatti, F, Varalli, L, Morini, L, Menzaghi, B, Farinazzo, M, Meli, R, Plaz Torres, M, Fanetti, I, Orellana, D, Zermiani, P, Zuin, M, De Bona, A, D'Arminio Monforte, A, Capretti, A, Taddei, M, Soncini, M, Spinetti, A, Zaltron, S, Pigozzi, M, Rossini, A, Pan, A, Dal Zoppo, S, Zoncada, A, Memoli, M, Salpietro, S, Hamid, H, Messina, E, Colombo, A, Giglio, O, Bonfanti, P, Molteni, C, Terreni, N, Spinzi, G, Conforti, S, Clerici, E, Menozzi, F, Buscarini, E, Centenaro, R, Corbellini, A, Noventa, F, Gritti, S, and Giani, P

Subjects
Simeprevir, Male, medicine.medical_specialty, Cirrhosis, SVR, Sofosbuvir, Sustained Virologic Response, liver cirrhosis, antiviral treatment, Hepacivirus, Antiviral Agents, law.invention, Randomized controlled trial, law, Virology, Internal medicine, Medicine, Humans, chronic hepatitis C, Prospective cohort study, DAA, Retrospective Studies, Hepatology, liver cirrhosi, business.industry, Hepatitis C, Hepatitis C, Chronic, Middle Aged, medicine.disease, Discontinuation, Regimen, Infectious Diseases, Treatment Outcome, business, medicine.drug
Abstract

In routine clinical practice, hepatitis C virus-infected patients can prematurely discontinue the prescribed regimen for several reasons. The aim of our study was to investigate sustained virological response (SVR12) rates in patients who prematurely discontinued directly acting antiviral (DAA) regimens and to assess the shortest effective duration of DAA able to lead to SVR12. We retrospectively collected the SVR rates of patients, registered in the NAVIGATORE-Lombardia Network database from January 2015, who discontinued DAAs before the predefined end of treatment. Overall, we included 365 patients, males were the majority (213, 58.4%), mean age was 60.5years, and 53 (14.5%) patients were HIV-co-infected. Liver cirrhosis was observed in 251 (68.8%) subjects, and the most represented genotypes were 1b (n=168, 46%) and 3 (n=59, 16.2%). DAA was discontinued a median of 1 (IQR 1–4) weeks before the predefined EOT, with 164 (44.9%) patients stopping DAAs at least 2weeks before the planned schedule. In patients with F0–F3 liver fibrosis, lower rates of SVR12 were observed in patients treated for

Published
2021

5. Erratum to: EuPRAXIA Conceptual Design Report (The European Physical Journal Special Topics, (2020), 229, 24, (3675-4284), 10.1140/epjst/e2020-000127-8)

Author

Assmann R. W., Weikum M. K., Akhter T., Alesini D., Alexandrova A. S., Anania M. P., Andreev N. E., Andriyash I., Artioli M., Aschikhin A., Audet T., Bacci A., Barna I. F., Bartocci S., Bayramian A., Beaton A., Beck A., Bellaveglia M., Beluze A., Bernhard A., Biagioni A., Bielawski S., Bisesto F. G., Bonatto A., Boulton L., Brandi F., Brinkmann R., Briquez F., Brottier F., Brundermann E., Buscher M., Buonomo B., Bussmann M. H., Bussolino G., Campana P., Cantarella S., Cassou K., Chance A., Chen M., Chiadroni E., Cianchi A., Cioeta F., Clarke J. A., Cole J. M., Costa G., Couprie M. -E., Cowley J., Croia M., Cros B., Crump P. A., D'Arcy R., Dattoli G., Del Dotto A., Delerue N., Del Franco M., Delinikolas P., De Nicola S., Dias J. M., Di Giovenale D., Diomede M., Di Pasquale E., Di Pirro G., Di Raddo G., Dorda U., Erlandson A. C., Ertel K., Esposito A., Falcoz F., Falone A., Fedele R., Ferran Pousa A., Ferrario M., Filippi F., Fils J., Fiore G., Fiorito R., Fonseca R. A., Franzini G., Galimberti M., Gallo A., Galvin T. C., Ghaith A., Ghigo A., Giove D., Giribono A., Gizzi L. A., Gruner F. J., Habib A. F., Haefner C., Heinemann T., Helm A., Hidding B., Holzer B. J., Hooker S. M., Hosokai T., Hubner M., Ibison M., Incremona S., Irman A., Iungo F., Jafarinia F. J., Jakobsson O., Jaroszynski D. A., Jaster-Merz S., Joshi C., Kaluza M., Kando M., Karger O. S., Karsch S., Khazanov E., Khikhlukha D., Kirchen M., Kirwan G., Kitegi C., Knetsch A., Kocon D., Koester P., Kononenko O. S., Korn G., Kostyukov I., Kruchinin K. O., Labate L., Le Blanc C., Lechner C., Lee P., Leemans W., Lehrach A., Li X., Li Y., Libov V., Lifschitz A., Lindstrom C. A., Litvinenko V., Lu W., Lundh O., Maier A. R., Malka V., Manahan G. G., Mangles S. P. D., Marcelli A., Marchetti B., Marcouille O., Marocchino A., Marteau F., Martinez de la Ossa A., Martins J. L., Mason P. D., Massimo F., Mathieu F., Maynard G., Mazzotta Z., Mironov S., Molodozhentsev A. Y., Morante S., Mosnier A., Mostacci A., Muller A. -S., Murphy C. D., Najmudin Z., Nghiem P. A. P., Nguyen F., Niknejadi P., Nutter A., Osterhoff J., Oumbarek Espinos D., Paillard J. -L., Papadopoulos D. N., Patrizi B., Pattathil R., Pellegrino L., Petralia A., Petrillo V., Piersanti L., Pocsai M. A., Poder K., Pompili R., Pribyl L., Pugacheva D., Reagan B. A., Resta-Lopez J., Ricci R., Romeo S., Rossetti Conti M., Rossi A. R., Rossmanith R., Rotundo U., Roussel E., Sabbatini L., Santangelo P., Sarri G., Schaper L., Scherkl P., Schramm U., Schroeder C. B., Scifo J., Serafini L., Sharma G., Sheng Z. M., Shpakov V., Siders C. W., Silva L. O., Silva T., Simon C., Simon-Boisson C., Sinha U., Sistrunk E., Specka A., Spinka T. M., Stecchi A., Stella A., Stellato F., Streeter M. J. V., Sutherland A., Svystun E. N., Symes D., Szwaj C., Tauscher G. E., Terzani D., Toci G., Tomassini P., Torres R., Ullmann D., Vaccarezza C., Valleau M., Vannini M., Vannozzi A., Vescovi S., Vieira J. M., Villa F., Wahlstrom C. -G., Walczak R., Walker P. A., Wang K., Welsch A., Welsch C. P., Weng S. M., Wiggins S. M., Wolfenden J., Xia G., Yabashi M., Zhang H., Zhao Y., Zhu J., Zigler A., Assmann, R. W., Weikum, M. K., Akhter, T., Alesini, D., Alexandrova, A. S., Anania, M. P., Andreev, N. E., Andriyash, I., Artioli, M., Aschikhin, A., Audet, T., Bacci, A., Barna, I. F., Bartocci, S., Bayramian, A., Beaton, A., Beck, A., Bellaveglia, M., Beluze, A., Bernhard, A., Biagioni, A., Bielawski, S., Bisesto, F. G., Bonatto, A., Boulton, L., Brandi, F., Brinkmann, R., Briquez, F., Brottier, F., Brundermann, E., Buscher, M., Buonomo, B., Bussmann, M. H., Bussolino, G., Campana, P., Cantarella, S., Cassou, K., Chance, A., Chen, M., Chiadroni, E., Cianchi, A., Cioeta, F., Clarke, J. A., Cole, J. M., Costa, G., Couprie, M. -E., Cowley, J., Croia, M., Cros, B., Crump, P. A., D'Arcy, R., Dattoli, G., Del Dotto, A., Delerue, N., Del Franco, M., Delinikolas, P., De Nicola, S., Dias, J. M., Di Giovenale, D., Diomede, M., Di Pasquale, E., Di Pirro, G., Di Raddo, G., Dorda, U., Erlandson, A. C., Ertel, K., Esposito, A., Falcoz, F., Falone, A., Fedele, R., Ferran Pousa, A., Ferrario, M., Filippi, F., Fils, J., Fiore, G., Fiorito, R., Fonseca, R. A., Franzini, G., Galimberti, M., Gallo, A., Galvin, T. C., Ghaith, A., Ghigo, A., Giove, D., Giribono, A., Gizzi, L. A., Gruner, F. J., Habib, A. F., Haefner, C., Heinemann, T., Helm, A., Hidding, B., Holzer, B. J., Hooker, S. M., Hosokai, T., Hubner, M., Ibison, M., Incremona, S., Irman, A., Iungo, F., Jafarinia, F. J., Jakobsson, O., Jaroszynski, D. A., Jaster-Merz, S., Joshi, C., Kaluza, M., Kando, M., Karger, O. S., Karsch, S., Khazanov, E., Khikhlukha, D., Kirchen, M., Kirwan, G., Kitegi, C., Knetsch, A., Kocon, D., Koester, P., Kononenko, O. S., Korn, G., Kostyukov, I., Kruchinin, K. O., Labate, L., Le Blanc, C., Lechner, C., Lee, P., Leemans, W., Lehrach, A., Li, X., Li, Y., Libov, V., Lifschitz, A., Lindstrom, C. A., Litvinenko, V., Lu, W., Lundh, O., Maier, A. R., Malka, V., Manahan, G. G., Mangles, S. P. D., Marcelli, A., Marchetti, B., Marcouille, O., Marocchino, A., Marteau, F., Martinez de la Ossa, A., Martins, J. L., Mason, P. D., Massimo, F., Mathieu, F., Maynard, G., Mazzotta, Z., Mironov, S., Molodozhentsev, A. Y., Morante, S., Mosnier, A., Mostacci, A., Muller, A. -S., Murphy, C. D., Najmudin, Z., Nghiem, P. A. P., Nguyen, F., Niknejadi, P., Nutter, A., Osterhoff, J., Oumbarek Espinos, D., Paillard, J. -L., Papadopoulos, D. N., Patrizi, B., Pattathil, R., Pellegrino, L., Petralia, A., Petrillo, V., Piersanti, L., Pocsai, M. A., Poder, K., Pompili, R., Pribyl, L., Pugacheva, D., Reagan, B. A., Resta-Lopez, J., Ricci, R., Romeo, S., Rossetti Conti, M., Rossi, A. R., Rossmanith, R., Rotundo, U., Roussel, E., Sabbatini, L., Santangelo, P., Sarri, G., Schaper, L., Scherkl, P., Schramm, U., Schroeder, C. B., Scifo, J., Serafini, L., Sharma, G., Sheng, Z. M., Shpakov, V., Siders, C. W., Silva, L. O., Silva, T., Simon, C., Simon-Boisson, C., Sinha, U., Sistrunk, E., Specka, A., Spinka, T. M., Stecchi, A., Stella, A., Stellato, F., Streeter, M. J. V., Sutherland, A., Svystun, E. N., Symes, D., Szwaj, C., Tauscher, G. E., Terzani, D., Toci, G., Tomassini, P., Torres, R., Ullmann, D., Vaccarezza, C., Valleau, M., Vannini, M., Vannozzi, A., Vescovi, S., Vieira, J. M., Villa, F., Wahlstrom, C. -G., Walczak, R., Walker, P. A., Wang, K., Welsch, A., Welsch, C. P., Weng, S. M., Wiggins, S. M., Wolfenden, J., Xia, G., Yabashi, M., Zhang, H., Zhao, Y., Zhu, J., and Zigler, A.

Abstract

Figure 20.1 was not correct in the published article. The original article has been corrected. The published apologizes for the inconvenience.

Published
2020

6. Status of the Horizon 2020 EuPRAXIA conceptual design study

Author

Weikum, MK, Akhter, T, Alesini, D, Alexandrova, AS, Anania, MP, Andreev, NE, Andriyash, IA, Aschikhin, A, Assmann, RW, Audet, T, Bacci, A, Barna, IF, Beaton, A, Beck, A, Beluze, A, Bernhard, A, Bielawski, S, Bisesto, FG, Brandi, F, Brinkmann, R, Bruendermann, E, Buescher, M, Bussmann, MH, Bussolino, G, Chance, A, Chen, M, Chiadroni, E, Cianchi, A, Clarke, JA, Cole, J, Couprie, ME, Croia, M, Cros, B, Crump, PA, Dattoli, G, Del Dotto, A, Delerue, N, De Nicola, S, Dias, JM, Dorda, U, Fedele, R, Pousa, A Ferran, Ferrario, M, Filippi, F, Fiore, G, Fonseca, RA, Galimberti, M, Gallo, A, Ghaith, A, Giove, D, Giribono, A, Gizzi, LA, Gruener, FJ, Habib, AF, Haefner, C, Heinemann, T, Hidding, B, Holzer, BJ, Hooker, SM, Hosokai, T, Huebner, M, Irman, A, Jafarinia, FJ, Jaroszynski, DA, Joshi, C, Kaluza, M, Kando, M, Karger, OS, Karsch, S, Khazanov, E, Khikhlukha, D, Knetsch, A, Kocon, D, Koester, P, Kononenko, OS, Korn, G, Kostyukov, I, Kruchinin, KO, Labate, L, Le Blanc, C, Lechner, C, Leemans, W, Lehrach, A, Li, X, Libov, V, Lifschitz, A, Litvinenko, V, Lu, W, Lundh, O, Maier, AR, Malka, V, Manahan, GG, Mangles, SPD, Marchetti, B, de la Ossa, A Martinez, Martins, JL, Mason, PD, Massimo, F, Mathieu, F, Maynard, G, Mazzotta, Z, Molodozhentsev, AY, Mostacci, A, Mueller, A-S, Murphy, CD, Najmudin, Z, Nghiem, PAP, Nguyen, F, Niknejadi, P, Osterhoff, J, Espinos, D Oumbarek, Papadopoulos, DN, Patrizi, B, Petrillo, V, Pocsai, MA, Poder, K, Pompili, R, Pribyl, L, Pugacheva, D, Rajeev, PP, Romeo, S, Conti, M Rossetti, Rossi, AR, Rossmanith, R, Roussel, E, Sahai, AA, Sarri, G, Schaper, L, Scherkl, P, Schramm, U, Schroeder, CB, Scifo, J, Serafini, L, Sheng, ZM, Siders, C, Silva, LO, Silva, T, Simon, C, Sinha, U, Specka, A, Streeter, MJV, Svystun, EN, Symes, D, Szwaj, C, Tauscher, GE, Terzani, D, Thompson, N, Toci, G, Tomassini, P, Torres, R, Ullmann, D, Vaccarezza, C, Vannini, M, Vieira, JM, Villa, F, Wahlstrom, C-G, Walczak, R, Walker, PA, Wang, K, Welsch, CP, Wiggins, SM, Wolfenden, J, Xia, G, Yabashi, M, Zhu, J, Zigler, A, IOP, Synchrotron SOLEIL (SSOLEIL), Centre National de la Recherche Scientifique (CNRS), Laboratoire de physique des gaz et des plasmas (LPGP), Université Paris-Sud - Paris 11 (UP11)-Centre National de la Recherche Scientifique (CNRS), Laboratoire Leprince-Ringuet (LLR), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Laboratoire pour l'utilisation des lasers intenses (LULI), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-École polytechnique (X)-Sorbonne Université (SU)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique des Lasers, Atomes et Molécules - UMR 8523 (PhLAM), Université de Lille-Centre National de la Recherche Scientifique (CNRS), Institut de Recherches sur les lois Fondamentales de l'Univers (IRFU), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Laboratoire de l'Accélérateur Linéaire (LAL), Université Paris-Sud - Paris 11 (UP11)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'optique appliquée (LOA), Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X)-École Nationale Supérieure de Techniques Avancées (ENSTA Paris), École polytechnique (X), Centre National de la Recherche Scientifique (CNRS)-École polytechnique (X)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-École polytechnique (X)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Paris-Sud - Paris 11 (UP11), École Nationale Supérieure de Techniques Avancées (ENSTA Paris)-École polytechnique (X)-Centre National de la Recherche Scientifique (CNRS), Weikum, M. K., Akhter, T., Alesini, D., Alexandrova, A. S., Anania, M. P., Andreev, N. E., Andriyash, I. A., Aschikhin, A., Assmann, R. W., Audet, T., Bacci, A., Barna, I. F., Beaton, A., Beck, A., Beluze, A., Bernhard, A., Bielawski, S., Bisesto, F. G., Brandi, F., Brinkmann, R., Bruendermann, E., Buscher, M., Bussmann, M. H., Bussolino, G., Chance, A., Chen, M., Chiadroni, E., Cianchi, A., Clarke, J. A., Cole, J., Couprie, M. E., Croia, M., Cros, B., Crump, P. A., Dattoli, G., Del Dotto, A., Delerue, N., De Nicola, S., Dias, J. M., Dorda, U., Fedele, R., Ferran Pousa, A., Ferrario, M., Filippi, F., Fiore, G., Fonseca, R. A., Galimberti, M., Gallo, A., Ghaith, A., Giove, D., Giribono, A., Gizzi, L. A., Gruner, F. J., Habib, A. F., Haefner, C., Heinemann, T., Hidding, B., Holzer, B. J., Hooker, S. M., Hosokai, T., Huebner, M., Irman, A., Jafarinia, F. J., Jaroszynski, D. A., Joshi, C., Kaluza, M., Kando, M., Karger, O. S., Karsch, S., Khazanov, E., Khikhlukha, D., Knetsch, A., Kocon, D., Koester, P., Kononenko, O. S., Korn, G., Kostyukov, I., Kruchinin, K. O., Labate, L., Blanc, C. L., Lechner, C., Leemans, W., Lehrach, A., Li, X., Libov, V., Lifschitz, A., Litvinenko, V., Lu, W., Lundh, O., Maier, A. R., Malka, V., Manahan, G. G., Mangles, S. P. D., Marchetti, B., Martinez De La Ossa, A., Martins, J. L., Mason, P. D., Massimo, F., Mathieu, F., Maynard, G., Mazzotta, Z., Molodozhentsev, A. Y., Mostacci, A., Mueller, A. -S., Murphy, C. D., Najmudin, Z., Nghiem, P. A. P., Nguyen, F., Niknejadi, P., Osterhoff, J., Oumbarek Espinos, D., Papadopoulos, D. N., Patrizi, B., Petrillo, V., Pocsai, M. A., Poder, K., Pompili, R., Pribyl, L., Pugacheva, D., Rajeev, P. P., Romeo, S., Rossetti Conti, M., Rossi, A. R., Rossmanith, R., Roussel, E., Sahai, A. A., Sarri, G., Schaper, L., Scherkl, P., Schramm, U., Schroeder, C. B., Scifo, J., Serafini, L., Sheng, Z. M., Siders, C., Silva, L. O., Silva, T., Simon, C., Sinha, U., Specka, A., Streeter, M. J. V., Svystun, E. N., Symes, D., Szwaj, C., Tauscher, G. E., Terzani, D., Thompson, N., Toci, G., Tomassini, P., Torres, R., Ullmann, D., Vaccarezza, C., Vannini, M., Vieira, J. M., Villa, F., Wahlstrom, C. -G., Walczak, R., Walker, P. A., Wang, K., Welsch, C. P., Wiggins, S. M., Wolfenden, J., Xia, G., Yabashi, M., Zhu, J., Zigler, A., Weikum, M K, Akhter, T, Alesini, D, Alexandrova, A S, Anania, M P, Andreev, N E, Andriyash, I A, Aschikhin, A, Assmann, R W, Audet, T, Bacci, A, Barna, I F, Beaton, A, Beck, A, Beluze, A, Bernhard, A, Bielawski, S, Bisesto, F G, Brandi, F, Brinkmann, R, Bruendermann, E, Büscher, M, Bussmann, M H, Bussolino, G, Chance, A, Chen, M, Chiadroni, E, Cianchi, A, Clarke, J A, Cole, J, Couprie, M E, Croia, M, Cros, B, Crump, P A, Dattoli, G, Del Dotto, A, Delerue, N, De Nicola, S, Dias, J M, Dorda, U, Fedele, R, Ferran Pousa, A, Ferrario, M, Filippi, F, Fiore, G, Fonseca, R A, Galimberti, M, Gallo, A, Ghaith, A, Giove, D, Giribono, A, Gizzi, L A, Grüner, F J, Habib, A F, Haefner, C, Heinemann, T, Hidding, B, Holzer, B J, Hooker, S M, Hosokai, T, Huebner, M, Irman, A, Jafarinia, F J, Jaroszynski, D A, Joshi, C, Kaluza, M, Kando, M, Karger, O S, Karsch, S, Khazanov, E, Khikhlukha, D, Knetsch, A, Kocon, D, Koester, P, Kononenko, O S, Korn, G, Kostyukov, I, Kruchinin, K O, Labate, L, Blanc, C Le, Lechner, C, Leemans, W, Lehrach, A, Li, X, Libov, V, Lifschitz, A, Litvinenko, V, Lu, W, Lundh, O, Maier, A R, Malka, V, Manahan, G G, Mangles, S P D, Marchetti, B, Martinez de la Ossa, A, Martins, J L, Mason, P D, Massimo, F, Mathieu, F, Maynard, G, Mazzotta, Z, Molodozhentsev, A Y, Mostacci, A, Mueller, A - S, Murphy, C D, Najmudin, Z, Nghiem, P A P, Nguyen, F, Niknejadi, P, Osterhoff, J, Oumbarek Espinos, D, Papadopoulos, D N, Patrizi, B, Petrillo, V, Pocsai, M A, Poder, K, Pompili, R, Pribyl, L, Pugacheva, D, Rajeev, P P, Romeo, S, Rossetti Conti, M, Rossi, A R, Rossmanith, R, Roussel, E, Sahai, A A, Sarri, G, Schaper, L, Scherkl, P, Schramm, U, Schroeder, C B, Scifo, J, Serafini, L, Sheng, Z M, Siders, C, Silva, L O, Silva, T, Simon, C, Sinha, U, Specka, A, Streeter, M J V, Svystun, E N, Symes, D, Szwaj, C, Tauscher, G E, Terzani, Davide, Thompson, N, Toci, G, Tomassini, P, Torres, R, Ullmann, D, Vaccarezza, C, Vannini, M, Vieira, J M, Villa, F, Wahlstrom, C - G, Walczak, R, Walker, P A, Wang, K, Welsch, C P, Wiggins, S M, Wolfenden, J, Xia, G, Yabashi, M, Zhu, J, and Zigler, A

Subjects
electron, History, [PHYS.PHYS.PHYS-ACC-PH]Physics [physics]/Physics [physics]/Accelerator Physics [physics.acc-ph], Physics and Astronomy(all), 01 natural sciences, 7. Clean energy, Plasmas, accelerators, 010305 fluids & plasmas, Education, Accelerator Physics, Acceleration, accelerators, Conceptual design, 0103 physical sciences, site, ddc:530, 010306 general physics, plasma, QC, Open innovation, Focus (computing), Detector, acceleration, Plasma acceleration, Accelerators and Storage Rings, Computer Science Applications, laser, MC3: Novel Particle Sources and Acceleration Techniques, Plasmas, Systems engineering, Physics::Accelerator Physics, Plasmas (physics) | Lasers | Laser wakefield
Abstract

The Horizon 2020 Project EuPRAXIA (European Plasma Research Accelerator with eXcellence In Applications) is producing a conceptual design report for a highly compact and cost-effective European facility with multi-GeV electron beams accelerated using plasmas. EuPRAXIA will be set up as a distributed Open Innovation platform with two construction sites, one with a focus on beam-driven plasma acceleration (PWFA) and another site with a focus on laser-driven plasma acceleration (LWFA). User areas at both sites will provide access to FEL pilot experiments, positron generation and acceleration, compact radiation sources, and test beams for HEP detector development. Support centres in four different countries will complement the pan-European implementation of this infrastructure., Proceedings of the 10th Int. Particle Accelerator Conf., IPAC2019, Melbourne, Australia

Published
2019
Full Text
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7. Erratum to: EuPRAXIA Conceptual Design Report

Author

Assmann, RW, Weikum, MK, Akhter, T, Alesini, D, Alexandrova, AS, Anania, MP, Andreev, NE, Andriyash, I, Artioli, M, Aschikhin, A, Audet, T, Bacci, A, Barna, IF, Bartocci, S, Bayramian, A, Beaton, A, Beck, A, Bellaveglia, M, Beluze, A, Bernhard, A, Biagioni, A, Bielawski, S, Bisesto, FG, Bonatto, A, Boulton, L, Brandi, F, Brinkmann, R, Briquez, F, Brottier, F, Bruendermann, E, Buescher, M, Buonomo, B, Bussmann, MH, Bussolino, G, Campana, P, Cantarella, S, Cassou, K, Chance, A, Chen, M, Chiadroni, E, Cianchi, A, Cioeta, F, Clarke, JA, Cole, JM, Costa, G, Couprie, M-E, Cowley, J, Croia, M, Cros, B, Crump, PA, D'Arcy, R, Dattoli, G, Del Dotto, A, Delerue, N, Del Franco, M, Delinikolas, P, De Nicola, S, Dias, JM, Di Giovenale, D, Diomede, M, Di Pasquale, E, Di Pirro, G, Di Raddo, G, Dorda, U, Erlandson, AC, Ertel, K, Esposito, A, Falcoz, F, Falone, A, Fedele, R, Ferran Pousa, A, Ferrario, M, Filippi, F, Fils, J, Fiore, G, Fiorito, R, Fonseca, RA, Franzini, G, Galimberti, M, Gallo, A, Galvin, TC, Ghaith, A, Ghigo, A, Giove, D, Giribono, A, Gizzi, LA, Gruener, FJ, Habib, AF, Haefner, C, Heinemann, T, Helm, A, Hidding, B, Holzer, BJ, Hooker, SM, Hosokai, T, Huebner, M, Ibison, M, Incremona, S, Irman, A, Iungo, F, Jafarinia, FJ, Jakobsson, O, Jaroszynski, DA, Jaster-Merz, S, Joshi, C, Kaluza, M, Kando, M, Karger, OS, Karsch, S, Khazanov, E, Khikhlukha, D, Kirchen, M, Kirwan, G, Kitegi, C, Knetsch, A, Kocon, D, Koester, P, Kononenko, OS, Korn, G, Kostyukov, I, Kruchinin, KO, Labate, L, Le Blanc, C, Lechner, C, Lee, P, Leemans, W, Lehrach, A, Li, X, Li, Y, Libov, V, Lifschitz, A, Lindstrom, CA, Litvinenko, V, Lu, W, Lundh, O, Maier, AR, Malka, V, Manahan, GG, Mangles, SPD, Marcelli, A, Marchetti, B, Marcouille, O, Marocchino, A, Marteau, F, Martinez de la Ossa, A, Martins, JL, Mason, PD, Massimo, F, Mathieu, F, Maynard, G, Mazzotta, Z, Mironov, S, Molodozhentsev, AY, Morante, S, Mosnier, A, Mostacci, A, Mueller, A-S, Murphy, CD, Najmudin, Z, Nghiem, PAP, Nguyen, F, Niknejadi, P, Nutter, A, Osterhoff, J, Oumbarek Espinos, D, Paillard, J-L, Papadopoulos, DN, Patrizi, B, Pattathil, R, Pellegrino, L, Petralia, A, Petrillo, V, Piersanti, L, Pocsai, MA, Poder, K, Pompili, R, Pribyl, L, Pugacheva, D, Reagan, BA, Resta-Lopez, J, Ricci, R, Romeo, S, Rossetti Conti, M, Rossi, AR, Rossmanith, R, Rotundo, U, Roussel, E, Sabbatini, L, Santangelo, P, Sarri, G, Schaper, L, Scherkl, P, Schramm, U, Schroeder, CB, Scifo, J, Serafini, L, Sharma, G, Sheng, ZM, Shpakov, V, Siders, CW, Silva, LO, Silva, T, Simon, C, Simon-Boisson, C, Sinha, U, Sistrunk, E, Specka, A, Spinka, TM, Stecchi, A, Stella, A, Stellato, F, Streeter, MJV, Sutherland, A, Svystun, EN, Symes, D, Szwaj, C, Tauscher, GE, Terzani, D, Toci, G, Tomassini, P, Torres, R, Ullmann, D, Vaccarezza, C, Valleau, M, Vannini, M, Vannozzi, A, Vescovi, S, Vieira, JM, Villa, F, Wahlstrom, C-G, Walczak, R, Walker, PA, Wang, K, Welsch, A, Welsch, CP, Weng, SM, Wiggins, SM, Wolfenden, J, Xia, G, Yabashi, M, Zhang, H, Zhao, Y, Zhu, J, Zigler, A, Engineering & Physical Science Research Council (EPSRC), Commission of the European Communities, and Science and Technology Facilities Council (STFC)

Subjects
Science & Technology, 02 Physical Sciences, Physics, Fluids & Plasmas, Physical Sciences, Physics, Multidisciplinary, ddc:530, 01 Mathematical Sciences, Applied Physics
Abstract

Figure 20.1 was not correct in the published article. The original article has been corrected. The published apologizes for the inconvenience.

Published
2020
Full Text
View/download PDF

8. Fabrication and characterizations of films made of Te/TeO 2 nanopowder consolidated by poly(methyl methacrylate)

Author

Palomba, M., Coscia, U., Carotenuto, G., De Nicola, S., Ambrosone, G., Palomba, M, Coscia, Ubaldo, Carotenuto, Gianfranco, Nicola, S. De, and Ambrosone, Giuseppina

Subjects
Poly(methyl methacrylate), Materials science, Photoconductivity, Scanning electron microscope, chemistry.chemical_element, Vibration milling, Condensed Matter Physics, chemistry.chemical_compound, chemistry, Chemical engineering, visual_art, X-ray crystallography, visual_art.visual_art_medium, Tellurium, Methyl methacrylate, Thin film, Power density
Abstract

Tellurium based material was obtained by binding nanosized tellurium grains, produced by dry vibration milling technique, with poly(methyl methacrylate) (PMMA). The morphology, structural and electrical properties of Te/PMMA films were investigated. The photoelectrical properties of the films were studied under white light illumination varying the optical power density from 2 to 170mW/cm2 and turning on and off the light cyclically. In order to determine the effects of milling technique two sets of Te/PMMA samples were produced by binding the “as received” and milled Te powders with PMMA. A quite prompt and evident photoresponse was observed for the material prepared with Te nanopowder, while not significant variations of the conductivity were detected in a reference sample fabricated with the as received coarse Te powder and illuminated in the same optical power density range. The origin of the photoconduction can be attributed to the enhancement of the ratio between TeO2 and Te phases in the nanopowder occurring during the milling stage. (© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)

Published
2015
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9. Imidazole-stabilized gold nanoparticles induce neuronal apoptosis: An in vitro and in vivo study

Author

Imperatore, R, Carotenuto, G, Di Grazia MA, Ferrandino, I, Palomba, Letizia, Mariotti, R, Vitale, E, De Nicola, S, Longo, A, Cristino, L., Imperatore, R., Carotenuto, G., Di Grazia, Ma, Ferrandino, I., Palomba, L, Mariotti, R., Vitale, E., De Nicola, S., Longo, A., and Cristino, L.

Subjects
Neurons, Time Factors, Imidazoles, apoptosis, Brain, Metal Nanoparticles, blood brain barrier, cytotoxicity, neuroblastoma, thiolato ligands, Blood-brain barrier, Endocytosis, nanoparticelle, barriera emato encefalica, apoptosi, Mice, Inbred C57BL, tumore, Injections, Intravenous, In Situ Nick-End Labeling, Animals, Humans, Tissue Distribution, Gold, Cell Shape
Abstract

Gold nanoparticles are increasingly being employed in innovative biological applications thanks to their advantages of material- and size-dependent physics and chemical interactions with the cellular systems. On the other hand, growing concern has emerged on the toxicity which would render gold-based nanoparticles harmful to cell cultures, animals, and humans. Emerging attention is focused on the interaction of gold nanoparticles with nervous system, especially regarding the ability to overcome the blood-brain barrier (BBB) which represents the major impediment to the delivery of therapeutics into the brain. We synthesized highly stable 2-mercapto-1-methylimidazole-stabilized gold-nanoparticles (AuNPs)-mmi to investigate their entry, accumulation, and toxicity in vitro (SH-SY5Y human neuroblastoma cells) and in vivo (brain of C57BL/6 mice) through optical and electron microscopy. After incubation in the cell culture medium at the lowest dose of 0.1 mg/mL the (AuNPs)-mmi nanoparticles were found compacted and recruited into endosome/lysosomes (1 h) before their fusion (2 h) and the onset of neuronal death by apoptosis (4 h) as proved by terminal-transferase-mediated dUTP nick end labeling assay and caspase-3 immunoreactivity. The ability of (AuNPs)-mmi to cross the BBB was assessed by injection in the caudal vein of C57BL/6 mice. Among different brain regions, the nanoparticles were found in the CaudatoPutamen area, mainly in the striatal neurons 4 h after injection. These neurons showed the typical hallmarks of apoptosis. Our findings provide, for the first time, the dynamic of 2-mercapto-1-methylimidazole nanogold uptake. The molecular mechanism which underlies the nanogold-driven apoptotic event is analyzed and discussed in order to take into account when designing nanomaterials to interface with biological structures. © 2014 Wiley Periodicals, Inc.

Published
2015
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10. Gold nanoparticles (AuNPs) in vivo and in vitro neuronal interaction

Author

Imperatore R., FERRANDINO, IDA, Longo A., Carotenuto G., De Nicola S., Vitale E., Cristino L., Daniela Parolaro - Tiziana Rubino - Roberto C. Melcangi, Imperatore, R., Ferrandino, Ida, Longo, A., Carotenuto, G., De Nicola, S., Vitale, E., and Cristino, L.

Abstract

Drugs delivery into the brain across the blood brain barrier has always remained a challenging task for neuroscientists. Nanotechnology is now providing new prospective in the treatment of neurological cancer, neurovascular disorders and neurodegenerative diseases. This study aims to explore whether gold nanoparticles (AuNPs) are able to cross the blood brain barrier (BBB) and more importantly whether they have cytotoxic effects after in vivo and in vitro uptake. We selected AuNPs for their stability, size controlled synthesis, relatively easy surface modification with amine and thiol groups and capability to be studied at ultrastructural level with electron microscopy. Alkanethiol pyrazol was used to stabilize AuNPs. Thiol ligands strongly bind gold molecules due to soft character of both Au and S. Nanoparticles with a mean particle size < 2 nm were obtained. These nanoparticles had an absorption spectrum at 350 nm and showed a broad emission ranging from 400 to 600 nm depending on their quantum size since their emission shift from green to red when they form clusters of ~200 nm of diameter. In order to explore in vivo uptake of gold nanoparticles, 0.2 ml of saline suspension containing AuNPs (1x105) or physiological solution (as control) were injected into the carotid artery respectively of n=3 anesthetized mice. After 90 min from administration, the animals were sacrificed and the hindbrain slices were studied with an epifluorescence microscope. A strong particleassociated florescence was observed in the Caudato Putamen region (CPu) for AuNPs treated and not for untreated control. The fluorescence shows a more evenly spread distribution in the neuronal but not in glial cells, as shown by GFAP, Iba1 and NeuN immunoistochemistry. In order to explore in vitro cellular uptake the human neuroblastoma cells SH-SY5Y were incubated with 1 ml of saline suspension containing AuNPs (1x105) at 20 min, 1, 2 and 4 hrs. AuNPs internalization was observed through Leica microscope workstation B6000 equipped for in vivo time lapse analysis and, furthermore, confirmed by transmission electron microscopy observations. The effect of AuNPs was investigated both in vivo and in vitro using caspase-3 immunoreactivity and TUNEL test which showed apoptosis. In vivo many CPu neurons loaded with AuNPs were both caspase- 3 and TUNEL labelled as in vitro neuroblastoma cells whereas glial cells were AuNPs unloaded and caspase-3 or TUNEL negatives. Our data suggest that AuNPs cross the BBB and have particular imaging properties since they cluster into the cells changing the emission spectrum from green to red. Noteworthy AuNPs are cytotoxic so they are an attractive platform for neurological diseases if specifically addressed toward target cells.

Published
2010

11. Synthesis of nanographite by laser induced thermal expansion of H2SO4 intercalated graphite lattice

Author

Carotenuto G., Longo A., Nicolais L., De Nicola S., Pugliese E., Ciofini M., Locatelli M., Lapucci A., and Meucci R.

Subjects
graphite intercalation compounds, infrared image, laser heating, thermal expansion
Abstract

We have experimentally investigated the expansion mechanism induced by laser irradiation of H2SO4 intercalated graphite. Intercalated graphite materials irradiated by laser allows to study reactions occurring in confined chemical conditions. We find that the laser-assisted reaction process is characterized by a threshold temperature of about 140{\deg}C followed by a fast rate of heating which produces a large amount of overheated gases and causes a violent expansion of the graphite crystal. We investigate the morphological changes undergone by irradiated graphite filaments using a combination of thermal and visible imaging technique which allows for the quantitative determination of temporal evolution of the thermal field during the heating stage and exfoliation of the grain.

Published
2014

12. Synthesis of nanographite by laser induced thermal expansion of H2SO4 intercalated graphite lattice

Author

Carotenuto, G., Longo, A., Nicolais, L., De Nicola, S., Pugliese, E., Ciofini, M., Locatelli, M., Lapucci, A., and Meucci, R.

Subjects
Condensed Matter - Materials Science, Materials Science (cond-mat.mtrl-sci), FOS: Physical sciences
Abstract

We have experimentally investigated the expansion mechanism induced by laser irradiation of H2SO4 intercalated graphite. Intercalated graphite materials irradiated by laser allows to study reactions occurring in confined chemical conditions. We find that the laser-assisted reaction process is characterized by a threshold temperature of about 140{\deg}C followed by a fast rate of heating which produces a large amount of overheated gases and causes a violent expansion of the graphite crystal. We investigate the morphological changes undergone by irradiated graphite filaments using a combination of thermal and visible imaging technique which allows for the quantitative determination of temporal evolution of the thermal field during the heating stage and exfoliation of the grain., Comment: pag 12 figure 7

Published
2014
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15. pi states in all-pnictide Josephson junctions

Author

Nappi, C., De Nicola, S., Adamo, M., and Sarnelli, E.

Subjects
Condensed Matter - Materials Science, Condensed Matter::Superconductivity, Condensed Matter - Superconductivity
Abstract

We study the Josephson effect in $s_{\pm}/I/s_{\pm}$ junctions made by two bands reversed sign s-wave ($s_{\pm}$) superconductive materials. We derive an equation providing the bound Andreev energy states parameterized by the band ratio $\alpha$, a parameter accounting for the weight of the second band with respect to the first one at the interface. For selected values of the band ratio and tunnel barrier amplitude, we predict various features of the Josephson current, among which a possible high temperature $\pi$ state of the junction (a doubly degenerate junction ground state) and a $\pi \rightarrow 0$ crossover with decreasing temperature.

Published
2012

24. Polarization spatial dynamics in a transverse multimode CO2 laser with optical feedback

Author

Meucci R., De Nicola S., Naimee K.A., Abdalah S.F., and Arecchi F.T.

Subjects
chaotic dynamics, polarization, Laser
Abstract

We experimentally study the polarization dynamics in a quasi isotropic CO2 laser emitting on the *01 TEM mode subjected to an optical feedback. We observe a complex dynamics in which spatial mode and polarization competition are involved. The observed dynamic is well reproduced by means of a model that provides a quantitative discrimination between the intrinsic asymmetry due to the kinetic coupling of molecules with different angular momenta and the anisotropy induced by the polarization feedback. Possible applications to polarization coding and synchronization will be presented.

Published
2012

30. Periodic and solitary wave solutions of generalized nonlinear Schrödinger equation using a Madelung fluid description

Author

Grecu D., Fedele R., De Nicola S., Grecu A.T., Visinescu A., D., Grecu, Fedele, Renato, S., de Nicola, A. T., Grecu, and A., Visinescu

Subjects
Nonlinear evolution, solitons, Madelung fluid, periodic solutions, periodic and solitary wave solutions of NLS equation
Abstract

The hydrodynamic fluid description, proposed many years ago by E. Madelung (1927) for quantum mechanics, is used to discuss the class of nonlinear Schr̈odinger equations. In the case of stationary profile solutions the equation satisfied by the fluid density ρ = {pipe}Ψ{pipe}2 is integrated and periodic solutions expressed through Jacobi elliptic functions are derived for cubic and cubic + quintic nonlinearities. In the limit case k2 = 1 the solitary wave solution found for the cubic + quintic nonlinearity proves to be much steeper and narrower than the one-soliton solution of the cubic NLS equation.

Published
2010

31. Fresnel tomography and interferometric technique for characterizing Laguerre-Gaussian beams

Author

De Nicola S., Fedele R., Manko M.A., Manko V.I., Meucci R., and Zito G.

Subjects
phase space, holographic interferometry, image reconstruction techniques, tomographic map
Abstract

Fresnel tomograms of Laguerre-Gaussian beams are found and the relation of the two-point spatial correlation function with the tomographic map is discussed. The spatial distribution and signature of vorticity of Laguerre-Gaussian modes is analyzed by measuring the two-point spatial correlation function of the one-dimensional projection of the vortex field. An interferometric approach, based on a Fourier projection algorithm, for the experimental determination of the two-point correlation function of the full complex vortex field at the cross-section plane of the recorded interference pattern is also described; this approach allows one to characterize the vortex structure and spatial coherence along the direction of propagation

Published
2010

32. Crossing of BBB using gold nanoparticles (AuNPS)

Author

Vitale E., Imperatore R., Ferrandino I., Luongo A., Carotenuto G., De Nicola S., Cristino L., E., Vitale, R., Imperatore, Ferrandino, Ida, A., Luongo, G., Carotenuto, S., DE NICOLA, and L. C. R. I. S. T. I. N., O.

Subjects
gold nanoparticles, blood brain barrier
Abstract

Delivery of pharmacologic agents to neurons in the brain across the blood brain barrier (BBB) remains a challenging task for neuroscientists. Because of their unique properties, nanoparticles have generated a great deal of interest for their potential use in therapeutics drug delivery. We investigated the use of colloidal gold (AuNP) in this context based on its characteristic stability as a metal nanoparticle. We explored the neuronal uptake of AuNPs both in vitro using SH-SY5Y human neuroblastoma cells and in vivo using direct brain injection in mice. AuNPs have a diameter of approximately 2 nm and an absorption spectrum with a peak at 350 nm. Due to their characteristic quantum size effect, the nanogold emission shifts from green to red upon forming clusters of approximately 200 nm in diameter. The clustered particles have a broad emission ranging from 400 to 600 nm. For the in vitro studies, we incubated SH-SY5Y cells with 1x105 AuNPs for 20 min, 1, 2 and 4 hrs. AuNP internalization was observed using a Leica microscope workstation B6000 equipped with an in vivo timelapse analysis capability. We confirmed our results using transmission electron microscopy (TEM). For in vivo, studies we injected a physiological solution containing 1x106 AuNPs into the carotid arteries of anesthetized mice (n=3). The physiological solution alone was injected into control mice for comparison. Our in vitro data demonstrated that gold-particles passed the cell membrane, clustered in the cytoplasm and induced apoptosis after 4 hrs of treatment. In vivo, a strong particle-associated florescence was observed in the cauda putamen region (CPu) 90 min after injection. Fluorescence was evenly distributed in the neuronal cells but was not observed in glial cells, as demonstrated by GFAP, Iba1 and NeuN immunoistochemistry. The cytotoxic effects of AuNPs were investigated both in vitro and in vivo using caspase-3 immunoreactivity and TUNEL assays for apoptosis. Our data suggest that AuNPs cross the BBB and have useful imaging properties that rely on clustering in cells, which changes their emission spectrum from green to red. Specific properties of these nanoparticles may offer new advantages as potential pharmaco-delivery tools in treatment of neurological diseases that may benefit from specific neuronal cell targeting.

Published
2010

36. Full characterization of the photorefractive bright soliton formation process using a digital holographic technique

Author

Merola F., Miccio L., Paturzo M., De Nicola S., and Ferraro P.

Subjects
photorefractive solitons, lithium niobate, Physics::Optics, Nonlinear Sciences::Pattern Formation and Solitons, digital holography
Abstract

An extensive characterization of the photorefractive bright soliton writing process in a lithium niobate crystal is presented. An interferometric approach based on a digital holographic technique has been used to reconstruct the complex wave field at the exit face of the crystal. Temporal evolution of both intensity and phase profile of the writing beam has been analysed. The effective changes of the refractive index of the medium during the writing process and after the soliton formation are determined from the optical phase distribution. This method provides a reliable way to observe the process of soliton formation, whereas the determination of the intensity distribution of the output beam does not show clearly whether the soliton regime has been achieved or not. Furthermore, a detailed analysis of the soliton in a steady-state situation and with different writing conditions is presented and discussed.

Published
2009

38. Special Solutions of Some Generalized NLS Equations

Author

Visinescu A., Grecu D., Fedele R., De Nicola S., M. Bunoiu, I. Malaescu, A., Visinescu, D., Grecu, Fedele, Renato, and S., De Nicola

Subjects
NLS equation, KdV equation, Madelung's fluid description, nonlinear partial differential equation, soliton
Abstract

Using a Madelung fluid description a discussion is given for some generalized NLS equations. Solitary wave and periodic solutions are obtained for constant and stationary profile current velocity.

Published
2009

46. Super-resolution in digital holography by a twodimensional dynamic phase grating

Author

Paturzo M., Merola F., Grilli S., De Nicola S., Finizio A., and Ferraro P.

Subjects
microscopy, diffraction, Physics::Optics, resolution, inteferometry
Abstract

An approach that uses an electro-optically tunable two dimensional phase grating to enhance the resolution in digital holographic microscopy is proposed. We show that, by means of a flexible hexagonal phase grating, it is possible to increase the numerical aperture of the imaging system, thus improving the spatial resolution of the images in two dimensions. The augment of the numerical aperture of the optical system is obtained by recording spatially multiplexed digital holograms. The grating tuneability allows one to adjust the intensity among the spatially multiplexed holograms maximizing the grating diffraction efficiency. Furthermore we demonstrate that the flexibility of the numerical reconstruction allows one to use selectively the diffraction orders carryinguseful information for increasing the spatial resolution. The proposedapproach can improve the capabilities of digital holography in three-dimensionalimaging and microscopy.

Published
2008

48. Infrared digital holographic imaging

Author

Ferraro P., Miccio L., Grilli S., Meucci R., De Nicola S., and Buah-Bassuah P.

Subjects
termoelectric, optical imaging, Physics::Physics Education, Physics::Optics, Astrophysics::Cosmology and Extragalactic Astrophysics, interferometry, infrared technology, Astrophysics::Galaxy Astrophysics
Abstract

A digital holographic technique has an extended measurement range and improved resolution at infrared wavelengths.

Published
2008
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49. Infrared digital reflective-holographic 3D shape measurements

Author

De Nicola S., Ferraro P., Grilli S., Miccio L., R. Meucci R., Buah-Bassuahc P. K., and Arecchi F. T.

Subjects
Infrared Holography, infrared, holography, optical metrology, interferometry, laser
Abstract

We present a series of experiments to demonstrate digital holography on reflective objects at wavelength 10.6 lm of a CO2 laser using a pyrocam array. Fresnel holograms of reflective objects are recorded by a Mach–Zehnder interferometer. We describe a method for improving the accuracy of the numerical reconstructions and for compensating the loss of resolution at longer wavelength by Fresnel reconstruction of digitally recorded infrared holograms.

Published
2008

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