1. Inflammatory bowel disease and its treatment in 2018: Global and Taiwanese status updates
- Author
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Chuan-Tai Chiu, Hau-Jyun Su, Jui-Ying Hsieh, Yen-Chun Lin, Chen-Yu Wang, Shu-Chen Wei, and Yu-Tse Chiu
- Subjects
medicine.medical_specialty ,Databases, Factual ,National Health Programs ,Population ,Taiwan ,Global Health ,Inflammatory bowel disease ,03 medical and health sciences ,0302 clinical medicine ,Epidemiology ,Prevalence ,Humans ,Medicine ,Intensive care medicine ,education ,lcsh:R5-920 ,education.field_of_study ,business.industry ,Incidence ,Incidence (epidemiology) ,Biosimilar ,General Medicine ,Inflammatory Bowel Diseases ,medicine.disease ,Magnetic Resonance Imaging ,digestive system diseases ,Transplantation ,Natural history ,Positron-Emission Tomography ,030220 oncology & carcinogenesis ,030211 gastroenterology & hepatology ,lcsh:Medicine (General) ,business ,Database research - Abstract
The global incidence and prevalence of inflammatory bowel disease (IBD) has increased over the last 2-4 decades, likely because of the adoption of a more “western” lifestyle as well as improved detection and awareness, and Taiwan is no exception. To characterize the increasing burden of IBD, we conducted a comprehensive review of IBD in the existing literature. The following parameters were reviewed: background knowledge and current standard care for IBD, including natural history, epidemiology, pathogenesis, diagnosis, monitoring, and treatment. In addition, new imaging modalities and treatment options such as combined positron emission tomography and magnetic resonance enterography, new biologic agents, small-molecule therapy, biosimilar therapeutics, mesenchymal stem cell transplantation, and fecal microbiota transplantation, all of which have been introduced for IBD management, were reviewed. We also used the hospital-based as well as population-based Taiwan National Health Insurance Research Database to assess Taiwan-specific trends for comparison with global trends. Keywords: Inflammatory bowel disease, 2018, Update
- Published
- 2019
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