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Aiming at the high dimensional problem of pathological image morphometric features and the small amount of applied samples in medical field, this paper presents the ReliefF-HEPSO head and neck cancer pathological image feature selection algorithm. The algorithm constructs a framework of multi-level dimensionality reduction. Firstly, according to the correlation of features and categories, the ReliefF algorithm is used to determine different feature weights to achieve initial dimensionality reduction. Secondly, the evolutionary neural strategy (ENS) is used to enrich the particle populations diversity of the binary particle swarm optimization (BPSO). A hybrid binary evolutionary particle swarm optimization (HEPSO) algorithm is proposed to automatically search for the best feature subsets of candidate feature subsets. Compared with 7 feature selection algorithms, the experiment proves that the algorithm can effectively screen out the morphological features of high correlation pathology images, achieve rapid dimensionality reduction, and obtain higher classification performance with fewer features.

With the acceleration of urban modernization, the use of prefabricated buildings on construction sites is increasing year by year. However, the following problems arise: the environmental quality of construction sites in our country is poor, the living comfort of prefabricated buildings is low, the recycling rate is low, and the indoor air is dirty, affecting the health and comfort of indoor personnel. Therefore, it is of great significance to complete the new wall for indoor air purification. Through the design of the three-layer interlayer, the heat exchange between the inside and outside air and the purification of the indoor air are realized, and a new type of movable plank house wall with low price and simple and ingenious structure is designed, which not only can improve the living comfort inside the plank house, but also can ensure the maximum embodiment of the energy-saving benefits of materials. The experimental results show that the indoor air quality of the air purification wall based on the heat exchange principle is improved by 21.6%, and the indoor temperature change in the air purification process can be effectively avoided.

The current study was designed to explore the role of signal transducer and activator of transcription 1 (Stat1) during tumor promotion using the mouse skin multistage carcinogenesis model. Topical treatment with both 12-O-tetradecanoylphorbol-13-acetate (TPA) and 3-methyl-1,8-dihydroxy-9-anthrone (chrysarobin or CHRY) led to rapid phosphorylation of Stat1 on both tyrosine (Y701) and serine (S727) residues in epidermis. CHRY treatment also led to upregulation of unphosphorylated Stat1 (uStat1) at later time points. CHRY treatment also led to upregulation of interferon regulatory factor 1 (IRF-1) mRNA and protein, which was dependent on Stat1. Further analyses demonstrated that topical treatment with CHRY but not TPA upregulated interferon-gamma (IFNγ) mRNA in the epidermis and that the induction of both IRF-1 and uStat1 was dependent on IFNγ signaling. Stat1 deficient (Stat1(-/-) ) mice were highly resistant to skin tumor promotion by CHRY. In contrast, the tumor response (in terms of both papillomas and squamous cell carcinomas) was similar in Stat1(-/-) mice and wild-type littermates with TPA as the promoter. Maximal induction of both cyclooxygenase-2 and inducible nitric oxide synthase in epidermis following treatment with CHRY was also dependent on the presence of functional Stat1. These studies define a novel mechanism associated with skin tumor promotion by the anthrone class of tumor promoters involving upregulation of IFNγ signaling in the epidermis and downstream signaling through activated (phosphorylated) Stat1, IRF-1 and uStat1.

In this paper, we investigated the morphology of IQC solidified at different cooling rates in an RS Al-8.2 at% manganese alloy and we analysed the formation of the unique morphology of IQC based on the stability of the solid-liquid interface and the symmetry of the microstructures

Etude de l'influence de la vitesse de refroidissement sur la microstructure de l'alliage Ni-27,5 % at. Al solidifie rapidement par le filage a l'etat liquide

The relation between the solidified morphology of icosahedral quasicrystals in Al-Mn binary alloys, and the constitution of alloys and the cooling rate during the solidification is investigated on the basis of reported results. A comparison in solidified morphology between crystalline and icosahedral quasicrystalline grains is also made. The experimental results and theoretical analysis indicate that morphological stability theory in crystalline solidification can also be applied in solidification of icosahedral quasicrystals.