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1. 7,8-dimethoxy-n-methylflindersine and 7,8-dimethoxy-3-(3-methylbut-2-enyl)-2-quinoline: antimalarial constituents of Araliopsis tabouensis

Author

Ezugwu, CO, Erdal, B, Chuck, D, Ikhlas, AK, Okunji, CO, Brian, MS, and Iwu, MM

Subjects
Araliopsis tabouensis, structural determination, antimalarial properties
Abstract

7,8-dimethoxy-N-methylflindersine and 7,8-dimethoxy-3-(3-methylbut-2-enyl)-2-quinoline were isolated from the stem bark of Araliopsis tabouensis and their structures were assigned base on their 1H and 13C-NMR, DEPT 135, Gradient HMBC, G-HMQC and G-DQF-Cosy characteristics. The IC50 value in antimalarial bioassays vary from 1.8 to 4.7 μg/ml. Key words: Araliopsis tabouensis, structural determination, antimalarial properties. Journal of Pharmaceutical and Allied Sciences Vol.2(2) 2005: 214-218

Published
2005

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