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40 results on '"Brandolini, M."'

2. Once-a-day (QD) vs. twice-daily (BID) nevirapine as simplification in PI-treated patients after 2 mos. of BID induction

Author

Maserati, R, Brandolini, M, Cattelan, A, Orani, A, Sighinolfi, L, Andreoni, M, Uglietti, A, Guaraldi, G, Sotgiu, G, Scalzini, A, Manconi, Pe, Nardini, G, Esposito, R, Chiodo, F, Ghinelli, F, Leoncini, F, Maggi, P, Dorigoni, N, D'Arminio Monforte, A, Pellicano', G, Pan, A, Fontana, T, Angioni, G, Francavilla, E, Malena, M, Manfrin, V, Lazzarin, A, Castagna, A, Rusconi, S, Mezzaroma, I, Cerioli, A., Maserati, Renato, Brandolini, Micaela, Cattelan, Annamaria, Orani, Anna, Sighinolfi, Laura, Andreoni, Massimo, Uglietti, Alessia, Guaraldi, Giovanni, Sotgiu, Giovanni, Snodo Study, Group, and Castagna, Antonella

Subjects
Male, nevirapine, HIV Infections, Pharmacology, Gastroenterology, law.invention, BID NVP, Randomized controlled trial, Liver Function Tests, law, Antiretroviral Therapy, Highly Active, Clinical endpoint, HIV Infection, Liver Function Test, virus diseases, Alanine Transaminase, gamma-Glutamyltransferase, Middle Aged, Viral Load, Infectious Diseases, Treatment Outcome, Tolerability, Female, Viral load, medicine.drug, Human, Adult, medicine.medical_specialty, Nevirapine, Settore MED/17 - Malattie Infettive, Adolescent, Anti-HIV Agents, antiretroviral therapy, once-daily, CD4+ T cell, Young Adult, Virology, Multicenter trial, Internal medicine, HIV/AIDS therapy, medicine, Humans, Adverse effect, HIV, antiretroviral therapy, therapy switch, nevirapine, adverse events, once-daily, business.industry, Anti-HIV Agent, HIV, therapy switch, adverse events, hepatitis B, Regimen, business
Abstract

To assess the efficacy and the tolerability of once-daily (QD) versus twice-daily (BID) nevirapine (NVP)-based highly active antiretroviral therapy (HAART) in virologically suppressed, HIV-positive patients switched from protease inhibitor (PI)-based HAART. Eligible patients were enrolled in the multicenter trial if HIV RNA levels were

Published
2011

14. Advanced Model for Truck Transportation Analysis

Author

Bruzzone, Agostino and Brandolini, M.

Subjects
Modlling & simulation, Supply chain, Transportation company, Transportation company, Supply chain, Modlling & simulation
Published
2005

20. Impact d'un message nutritionnel concernant les protéines sur les habitudes alimentaires des personnes âgées et sur leurs attitudes vis à vis de l'alimentation et de la santé

Author

Rousset, S, Lhoutellier, P., Droit-Volet, Sylvie, Grandjean, V., Brandolini, M., Boirie, Yves, Laboratoire de psychologie sociale et de psychologie cognitive (LAPSCO), and Université Blaise Pascal - Clermont-Ferrand 2 (UBP)-Centre National de la Recherche Scientifique (CNRS)

Subjects
[SCCO.PSYC]Cognitive science/Psychology
Published
2003

32. Analisi delle tecniche di anestesia e dei tempi perioperatori in un campione di ospedali del veneto

Author

Sartore, A., Sammartano, S., Preciso, G., Manani, G., DALLA MORA, E., Faccin, G., Alati, G., Brandolini, M., Bonato, A., Garro, G., Valenti, S., Cirillo, F., Didon, M., Gallo, L., Girotto, T., Padovan, L., Dallacqua, G., Pizzolato, F., Vestali, A., Zanovello, G. P., DE ZEN, G. F., Piccinni, P., Civran, E., Zanette, Gastone, Corlian, P., Ongaro, L., Catturani, G., Vitaliani, V., Cucci, L., RIANIMAZIONE DEL VENETO, L. N. A. P. O. L. I. T. A. N. I. COLLEGIO DEI PRIMARI DI ANESTESIA E., and PROBLEMI PERIOPERATORI, GRUPPO DI STUDIO PER I.

Published
1996

36. Fast and real-time electrical transistor assay for quantifying SARS-CoV-2 neutralizing antibodies

Author

Francesco Decataldo, Laura Grumiro, Maria Michela Marino, Francesca Faccin, Catia Giovannini, Martina Brandolini, Giorgio Dirani, Francesca Taddei, Davide Lelli, Marta Tessarolo, Maria Calienni, Carla Cacciotto, Antonio Lavazza, Beatrice Fraboni, Alessandra Scagliarini, Vittorio Sambri, Decataldo F., Grumiro L., Marino M.M., Faccin F., Giovannini C., Brandolini M., Dirani G., Taddei F., Lelli D., Tessarolo M., Calienni M., Cacciotto C., Lavazza A., Fraboni B., Scagliarini A., and Sambri V.

Subjects
Electrical Plaque Reduction Neutralization Test, Organic Electrochemical Transistor, Mechanics of Materials, SARS-CoV-2, viruses, Viral Neutralization, TA401-492, General Materials Science, SARS-CoV-2 neutralization CPE OECT, Materials of engineering and construction. Mechanics of materials
Abstract

Due to the SARS-CoV-2 pandemic renewed attention has been directed towards viral neutralization assays and neutralizing antibodies quantification, for vaccine pre-clinical trials and determining vaccine efficacy over time. The gold standard to assess antibody titer is the plaque reduction neutralization test, an end-point assay which evaluates the highest serum antibody dilution that neutralizes viral replication, by inspecting the cytopathic effect induced on cell cultures. Here, we use planar, PEDOT:PSS-based organic electrochemical transistors for real-time, remote-controlled, reliable and fast electrical monitoring of the cytopathic effect induced by SARS29 CoV-2 on Vero E6 cell lines, allowing the quantification of serum neutralizing titer. Our low-cost and scalable device has the potential to speed-up large-scale viral neutralization screening without the need for cancerous staining or highly specialized operators. Finally, the technology could be easily transferred to assess neutralizing antibody response towards different viruses in their permissive cell substrates.

Published
2021
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37. Correlating qRT-PCR, dPCR and Viral Titration for the Identification and Quantification of SARS-CoV-2: A New Approach for Infection Management

Author

Fabio Gentilini, Maria Michela Marino, Vittorio Sambri, Giorgio Dirani, Laura Grumiro, Martina Brandolini, Francesca Taddei, Michela Fantini, Maria Elena Turba, Agata Scalcione, Silvia Zannoli, Brandolini M., Taddei F., Marino M.M., Grumiro L., Scalcione A., Turba M.E., Gentilini F., Fantini M., Zannoli S., Dirani G., and Sambri V.

Subjects
0301 basic medicine, viral titration, Virus Cultivation, 030106 microbiology, TCID50/mL, Biology, Chlorocebus aethiop, Polymerase Chain Reaction, Microbiology, Article, law.invention, 03 medical and health sciences, law, Virology, Chlorocebus aethiops, Animals, Humans, RNA copies, Digital polymerase chain reaction, Vero Cells, Polymerase chain reaction, Cells, Cultured, Ct, Digital Technology, Animal, Reverse Transcriptase Polymerase Chain Reaction, SARS-CoV-2, dPCR, RNA, COVID-19, qRT-PCR, Gold standard (test), Viral Load, RNA copie, QR1-502, 030104 developmental biology, Infectious Diseases, Real-time polymerase chain reaction, Vero Cell, Vero cell, RNA, Viral, RNA extraction, Viral load, Human
Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first identified in Wuhan, China, in late 2019 and is the causative agent of the coronavirus disease 2019 (COVID-19) pandemic. Quantitative reverse-transcription polymerase chain reaction (qRT-PCR) represents the gold standard for diagnostic assays even if it cannot precisely quantify viral RNA copies. Thus, we decided to compare qRT-PCR with digital polymerase chain reaction (dPCR), which is able to give an accurate number of RNA copies that can be found in a specimen. However, the aforementioned methods are not capable to discriminate if the detected RNA is infectious or not. For this purpose, it is necessary to perform an endpoint titration on cell cultures, which is largely used in the research field and provides a tissue culture infecting dose per mL (TCID50/mL) value. Both research and diagnostics call for a model that allows the comparison between the results obtained employing different analytical methods. The aim of this study is to define a comparison among two qRT-PCR protocols (one with preliminary RNA extraction and purification and an extraction-free qRT-PCR), a dPCR and a titration on cell cultures. The resulting correlations yield a faithful estimation of the total number of RNA copies and of the infectious viral burden from a Ct value obtained with diagnostic routine tests. All these estimations take into consideration methodological errors linked to the qRT-PCR, dPCR and titration assays.

Published
2021

39. I poligoni: dai mosaici dell’Alhambra alle incisioni di Escher

Author

Brandolini B, Tricarico M, B. Brandolini, M. Lapegna, Brandolini, B., Tricarico, M., Brandolini, B, Lapegna, M., Brandolini B, and Tricarico M

Subjects
Escher, Settore MAT/05 - Analisi Matematica, Poligoni
Abstract

Descrizione delle attività svolte durante l'omonimo laboratorio tenuto per il PLS matematica nell'anno 2018

Published
2019

40. Una introduzione all'aritmetica modulare

Author

M. R. Celentani, G. Cutolo, B. Brandolini, M. Lapegna, Celentani, M. R., and Cutolo, G.

Subjects
Aritmetica modulare
Abstract

Questo articolo è pensato per studenti non universitari che abbiano qualche curiosità nei confronti di un argomento non abitualmente incontrato nei corsi scolastici. La trattazione è elementare e di tono informale quanto possibile, anche se non rinuncia del tutto a dare qualche indicazione di cosa si possa incontrare oltre questo primo approccio, e non ha alcuna pretesa di completezza.

Published
2019

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