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It has been known for about sixty years that proton and heavy ion therapy is a very powerful radiation procedure for treating tumours. It has an innate ability to irradiate tumours with greater doses and spatial selectivity compared with electron and photon therapy and hence is a tissue sparing procedure. For more than twenty years powerful lasers have generated high energy beams of protons and heavy ions and hence it has been frequently speculated that lasers could be used as an alternative to RF accelerators to produce the particle beams necessary for cancer therapy. The present paper reviews the progress made towards laser driven hadron cancer therapy and what has still to be accomplished to realise its inherent enormous potential., Comment: 40 pages, 24 figures

Suitable instrumentation for laser-accelerated proton (ion) beams is critical for development of integrated, laser-driven ion accelerator systems. Instrumentation aimed at beam diagnostics and control must be applied to the driving laser pulse, the laser-plasma that forms at the target and the emergent proton (ion) bunch in a correlated way to develop these novel accelerators. This report is a brief overview of established diagnostic techniques and new developments based on material presented at the first workshop on 'Instrumentation for Diagnostics and Control of Laser-accelerated Proton (Ion) Beams' in Abingdon, UK. It includes radiochromic film (RCF), image plates (IP), micro-channel plates (MCP), Thomson spectrometers, prompt inline scintillators, time and space-resolved interferometry (TASRI) and nuclear activation schemes. Repetition-rated instrumentation requirements for target metrology are also addressed. © 2013 Associazione Italiana di Fisica Medica.

We demonstrate generation of 10-20 MeV/u ions with a compact 4 TW laser using a gas target mixed with submicron clusters, corresponding to tenfold increase in the ion energies compared to previous experiments with solid targets. It is inferred that the high energy ions are generated due to formation of a strong dipole vortex structure. The demonstrated method has a potential to construct compact and high repetition rate ion sources for hadron therapy and other applications., Comment: 7 pages, 4 figures

Proposed fourth generation light sources using SASE FELs to generate short pulse, coherent, X-rays require demonstration of high brightness electron sources. The Gun Test Facility (GTF) at SLAC was built to test high brightness sources for the proposed Linac Coherent Light Source at SLAC. The transverse emittance measurements are made at nearly 30 MeV by measuring the spot size on a YAG screen using the quadrupole scan technique. The emittance was measured to vary from 1 to 3.5 mm-mrad as the charge is increased from 50 to 350 pC using a laser pulse width of 2 ps FWHM. The measurements are in good agreement with simulation results using the LANL version of PARMELA., 12 pages, 4 figures, contributed to The 23rd Int. FEL Conf., Darmstadt, 20-24 Aug. 2001

We report the results of a recent beam dynamics study, motivated by the need to redesign the LCLS photoinjector, that lead to the discovery of a new effective working point for a split RF photoinjector. We consider the emittance compensation regime of a space charge beam: by increasing the solenoid strength, the emittance evolution shows a double minimum behavior in the drifting region. If the booster is located where the relative emittance maximum and the envelope waist occur, the second emittance minimum can be shifted to the booster exit and frozen at a very low level (0.3 mm-mrad for a 1 nC flat top bunch), to the extent that the invariant envelope matching conditions are satisfied. Standing Wave Structures or alternatively Traveling Wave Structures embedded in a Long Solenoid are both candidates as booster linac. A careful measurement of the emittance evolution as a function of position in the drifting region is necessary to verify the computation and to determine experimentally the proper position of the booster cavities. The new design study and supporting experimental program under way at the SLAC Gun Test Facility are discussed., Comment: 4 pages, 7 figures, contributed to EPAC00

We have measured the ion yields for helium ionized by 120 fs, 614 nm laser pulses for intensities near 1016 W/cm2. We have found that for these ultrashort pulses the He+2 data exhibit a feature which saturates in parallel with the He+ signal indicating that the ionization may proceed nonsequentially. We propose a new mechanism, which can exist only in the tunneling regime, for such nonsequential ionization.

Our final results of measurements at SLAC of the spin dependent asymmetry in the deep inelastic scattering of longitudinally polarized electrons by longitudinally polarized protons are presented. Data were obtained at a scattering angle of 10° and for incident energies of 16.2 and 22.7 GeV, which cover the kinematic range 0.18