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3 results on '"Bachmann, Maie"'

2. Chronic kidney disease and neurological disorders: are uraemic toxins the missing piece of the puzzle?

Author

Liabeuf, Sophie, Pepin, Marion, Franssen, Casper, Viggiano, Davide, Carriazo, Sol, Gansevoort, Ron, Gesualdo, Loreto, Hafez, Gaye, Malyszko, Jolanta, Mayer, Christopher, Nitsch, Dorothea, Ortiz, Alberto, Pešić, Vesna, Wiecek, Andrzej, Massy, Ziad, Capasso, Giovambattista, Andrade, Alexandre, Bachmann, Maie, Bumblyte, Inga, Covic, Adrian Constantin, Delgado, Pilar, Endlich, Nicole, Engvig, Andreas, Fouque, Denis, Frische, Sebastian, Garneata, Liliana, Giannakou, Konstantinos, Goumenos, Dimitrios, Kartal, Ayşe Tuğba, Mani, Laila-Yasmin, Marti, Hans-Peter, Nielsen, Rikke, Rroji, Merita, Sakkas, Giorgos, Spasovski, Goce, Stevens, Kate, Vazelov, Evgueniy, Zacharia, Lefteris, Ferreira, Ana Carina, Hoorn, Ewout, Figurek, Andreja, Unwin, Robert, Wagner, Carsten, Wanner, Christoph, BRUCHFELD, Annette, Fridolin, Ivo, Romeo, Maria José Soler, Barbieri, Michelangela, Batinić, Bojan, Carrasco, Laura, Martino, Gianvito, Raso, Francesco Mattace, Nistor, Ionut, Paolisso, Giuseppe, Rastenytė, Daiva, Stefan, Gabriel, Tedeschi, Gioacchino, Bikbov, Boris, Endlich, Karl Hans, Godefroy, Olivier, Chillon, Jean-Marc, Kossioni, Anastassia, Kurganaite, Justina, Perico, Norberto, Remuzzi, Giuseppe, Grodzicki, Tomasz, Trepiccione, Francesco, Zoccali, Carmine, Arici, Mustafa, Blankestijn, Peter, Eckardt, Kai-Uwe, Fliser, Danilo, Jiménez, Eugenio Gutiérrez, Konig, Maximilian, Rychlik, Ivan, Deleidi, Michela, REUSZ, George, Mécanismes physiopathologiques et conséquences des calcifications vasculaires - UR UPJV 7517 (MP3CV), Université de Picardie Jules Verne (UPJV)-CHU Amiens-Picardie, Hôpital Ambroise Paré [AP-HP], Groningen University Medical Centre, Department of Nephrology [Groningue, Pays-Bas], University Medical Center Groningen [Groningen] (UMCG), CeRTA, Liabeuf, S., Pepin, M., Franssen, C. F. M., Viggiano, D., Carriazo, S., Gansevoort, R. T., Gesualdo, L., Hafez, G., Malyszko, J., Mayer, C., Nitsch, D., Ortiz, A., Pesic, V., Wiecek, A., and Massy, Z. A.

Subjects
medicine.medical_specialty, CLINICAL-OUTCOMES, HEMODIALYSIS, Movement disorders, 030232 urology & nephrology, RENAL DYSFUNCTION, URIC-ACID, Review, 03 medical and health sciences, 0302 clinical medicine, PARKINSONS-DISEASE, Diabetes mellitus, Internal medicine, Epidemiology, medicine, CKD, INDOXYL SULFATE, AcademicSubjects/MED00340, Stroke, Depression (differential diagnoses), RISK, Transplantation, Kidney, COMPLICATIONS, business.industry, cardiovascular, medicine.disease, COGNITIVE FUNCTION, indoxyl sulphate, stroke, 3. Good health, medicine.anatomical_structure, Clinical research, Nephrology, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, medicine.symptom, business, 030217 neurology & neurosurgery, Kidney disease, uraemic toxins
Abstract

Chronic kidney disease (CKD) perturbs the crosstalk with others organs, with the interaction between the kidneys and the heart having been studied most intensively. However, a growing body of data indicates that there is an association between kidney dysfunction and disorders of the central nervous system. In epidemiological studies, CKD is associated with a high prevalence of neurological complications, such as cerebrovascular disorders, movement disorders, cognitive impairment and depression. Along with traditional cardiovascular risk factors (such as diabetes, inflammation, hypertension and dyslipidaemia), non-traditional risk factors related to kidney damage (such as uraemic toxins) may predispose patients with CKD to neurological disorders. There is increasing evidence to show that uraemic toxins, for example indoxyl sulphate, have a neurotoxic effect. A better understanding of factors responsible for the elevated prevalence of neurological disorders among patients with CKD might facilitate the development of novel treatments. Here, we review (i) the potential clinical impact of CKD on cerebrovascular and neurological complications, (ii) the mechanisms underlying the uraemic toxins’ putative action (based on pre-clinical and clinical research) and (iii) the potential impact of these findings on patient care., Graphical Abstract Graphical Abstract

Published
2021
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3. Cognitive disorders in patients with chronic kidney disease: specificities of clinical assessment

Author

Pépin, Marion, Ferreira, Ana Carina, Arici, Mustafa, Bachmann, Maie, Barbieri, Michelangela, Bumblyte, Inga Arune, Carriazo, Sol, Delgado, Pilar, Garneata, Liliana, Giannakou, Konstantinos, Godefroy, Olivier, Grodzicki, Tomasz, Klimkowicz-Mrowiec, Aleksandra, Kurganaite, Justina, Liabeuf, Sophie, Mocanu, Carmen Antonia, Paolisso, Giuseppe, Spasovski, Goce, Vazelov, Evgueniy Stefanov, Viggiano, Davide, Zoccali, Carmine, Massy, Ziad A, Więcek, Andrzej, and NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)

Abstract

publishersversion published

Published
2022

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