8 results on '"Bacchin, R"'
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2. Relationship between pain and motor and non-motor symptoms in Parkinson's disease
- Author
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Defazio, G, Antonini, A, Tinazzi, M, Gigante, A F, Pietracupa, S, Pellicciari, R, Bloise, M, Bacchin, R, Marcante, A, Fabbrini, G, Berardelli, A, and Domenicucci, Maurizio
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Adult ,Male ,0301 basic medicine ,medicine.medical_specialty ,Parkinson's disease ,Disease ,motor symptoms ,non-motor symptoms ,pain ,Logistic regression ,03 medical and health sciences ,Cognition ,Sex Factors ,0302 clinical medicine ,Internal medicine ,Humans ,Medicine ,Neurology ,Neurology (clinical) ,Fatigue ,Aged ,Aged, 80 and over ,Movement Disorders ,Depression ,Mood Disorders ,business.industry ,Chronic pain ,Parkinson Disease ,Odds ratio ,Middle Aged ,medicine.disease ,030104 developmental biology ,Mood ,Italy ,Physical therapy ,Non motor ,Female ,Chronic Pain ,business ,030217 neurology & neurosurgery - Abstract
Background and purpose Although female gender, depressive symptoms and medical conditions predisposing to pain are more common in patients with Parkinson's disease (PD) with pain, no study has yet explored the relationship between pain and other non-motor symptoms (NMS). Methods A total of 321 consecutive patients with PD [190 men/131 women aged 68.3 (SD 9.2) years] attending four Italian movement disorder clinics were studied. Demographic/clinical data were obtained by a standardized interview and the NMS scale. The association of pain with motor and NMS was assessed by multivariable logistic regression models. Results At the time of the study, 180 patients with PD (56%) reported chronic pain that, in most cases, was described as being muscular or arthralgic pain. Pain preceded the onset of motor signs in 36/180 patients. In the main-effect model, factors independently associated with pain were female sex [odds ratio (OR), 2.1; P = 0.01], medical conditions predisposing to pain (OR, 2.9; P < 0.001), Hoehn–Yahr staging (OR, 1.9; P = 0.04), motor complications (OR, 4.7; P = 0.04) and NMS belonging to the sleep/fatigue (OR, 1.6; P = 0.04) and mood/cognition (OR, 1.6; P = 0.03) domains. Most explanatory variables in the multivariable analysis were similarly distributed in patients in whom pain may have been related to PD or to a cause other than PD. Conclusions We confirm that pain in PD is more frequent in women and in subjects with medical conditions predisposing to painful symptoms. Moreover, this strengthens the association between pain and motor severity measures and NMS domains, particularly sleep and mood disturbances.
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- 2017
3. Infectious complications in liver transplant recipients in Italy: Logistic and research projects
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Viscoli, C., Dimitri, P., Di Domenico, S., Mannelli, S., Dodi, F., Veroni, L., Amoroso, P., Andorno, E., Avolio, A. W., Bacchin, R., Barbieri, V., Burra, P., Catelan, A. M., Cautero, N., Ceriello, A., Corti, A., De Gasperi, A., Di Florio, E., Faustini, M., Ferretti, G., Gerunda, G., Guaraldi, G., Lupo, L., Militerno, G., Morgagni, R., Pannarale, O., Paone, G., Papa, V., Paterson, D. L., Pellizzari, A., Regalia, E., Ronzoni, G., Rossi, M., Sangiorgi, G., Spada, M., Tebaldi, A., Tisone, G., Toniutto, P., Volpi, A., Valente, U., and Valmasoni, M.
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Liver transplantation ,Infections ,«Program Infections in Liver Transplantation» - Published
- 2001
4. Infectious complications in liver transplant recipients in Italy: Logistic and research projects | Complicanze infettive nel trapianto di fegato in Italia: Stato attuale e prospettive di studio
- Author
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Viscoli, C., Dimitri, P., Di Domenico, S., Mannelli, S., Dodi, F., Veroni, L., Amoroso, P., Andorno, E., Avolio, A. W., Bacchin, R., Barbieri, V., Burra, P., Catelan, A. M., Cautero, N., Ceriello, A., Corti, A., Gasperi, A., Di Florio, E., Faustini, M., Ferretti, G., giorgio gerunda, Guaraldi, G., Lupo, L., Militerno, G., Morgagni, R., Pannarale, O., Paone, G., Papa, V., Paterson, D. L., Pellizzari, A., Regalia, E., Ronzoni, G., Rossi, M., Sangiorgi, G., Spada, M., Tebaldi, A., Tisone, G., Toniutto, P., Volpi, A., Valente, U., and Valmasoni, M.
5. Infectious complications in liver transplant recipients in Italy: Logistic and research projects,Complicanze infettive nel trapianto di fegato in Italia: Stato attuale e prospettive di studio
- Author
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Viscoli, C., Dimitri, P., Di Domenico, S., Mannelli, S., Dodi, F., Veroni, L., Amoroso, P., Andorno, E., Avolio, A. W., Bacchin, R., Barbieri, V., Burra, P., Catelan, A. M., Cautero, N., Ceriello, A., Corti, A., Gasperi, A., Di Florio, E., Faustini, M., Ferretti, G., Gerunda, G., Guaraldi, G., Lupo, L., Militerno, G., Morgagni, R., Pannarale, O., Paone, G., Papa, V., Paterson, D. L., Pellizzari, A., Regalia, E., Ronzoni, G., Rossi, M., Gabriela Sangiorgi, Spada, M., Tebaldi, A., Tisone, G., Toniutto, P., Volpi, A., Valente, U., and Valmasoni, M.
6. Incremental value of amyloid-PET versus CSF in the diagnosis of Alzheimer’s disease
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Giordano Savelli, Marco Salvatore, Carlo Cavaliere, Davide V. Moretti, Valentina Garibotto, Matteo Cotta Ramusino, Matteo Bauckneht, Anna Tarallo, Maura Parapini, Giovanni B. Frisoni, Flavio Nobili, Alessandra Dodich, Nicola Salvadori, Aline Mendes, Daniele Altomare, Elena Salvatore, Agnese Picco, Silvia Morbelli, Ruggero Bacchin, Massimo E. Dottorini, Marina Boccardi, Frédéric Assal, Cristina Tranfaglia, Michele Tinazzi, Lucia Farotti, Alfredo Costa, Ramusino, M. C., Garibotto, V., Bacchin, R., Altomare, D., Dodich, A., Assal, F., Mendes, A., Costa, A., Tinazzi, M., Morbelli, S. D., Bauckneht, M., Picco, A., Dottorini, M. E., Tranfaglia, C., Farotti, L., Salvadori, N., Moretti, D., Savelli, G., Tarallo, A., Nobili, F., Parapini, M., Cavaliere, C., Salvatore, E., Salvatore, M., Boccardi, M., and Frisoni, G. B.
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Oncology ,medicine.medical_specialty ,Positron emission tomography ,Amyloid pet ,tau Proteins ,Disease ,ddc:616.0757 ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Cerebrospinal fluid ,Incremental diagnostic value ,Alzheimer Disease ,Internal medicine ,mental disorders ,medicine ,Dementia ,Humans ,Radiology, Nuclear Medicine and imaging ,Cognitive Dysfunction ,Amyloid beta-Peptides ,medicine.diagnostic_test ,business.industry ,Alzheimer’s disease ,Mild cognitive impairment ,Neuropsychology ,General Medicine ,Alzheimer's disease ,medicine.disease ,Peptide Fragments ,ddc:616.8 ,030220 oncology & carcinogenesis ,Positron-Emission Tomography ,ddc:618.97 ,Etiology ,Biomarker (medicine) ,business ,Biomarkers - Abstract
Purpose: To compare the incremental diagnostic value of amyloid-PET and CSF (Aβ42, tau, and phospho-tau) in AD diagnosis in patients with mild cognitive impairment (MCI) or mild dementia, in order to improve the definition of diagnostic algorithm. Methods: Two independent dementia experts provided etiological diagnosis and relative diagnostic confidence in 71 patients on 3 rounds, based on (1) clinical, neuropsychological, and structural MRI information alone; (2) adding one biomarker (CSF amyloid and tau levels or amyloid-PET with a balanced randomized design); and (3) adding the other biomarker. Results: Among patients with a pre-biomarker diagnosis of AD, negative PET induced significantly more diagnostic changes than amyloid-negative CSF at both rounds 2 (CSF 67%, PET 100%, P = 0.028) and 3 (CSF 0%; PET 78%, P < 0.001); PET induced a diagnostic confidence increase significantly higher than CSF on both rounds 2 and 3. Conclusions: Amyloid-PET should be prioritized over CSF biomarkers in the diagnostic workup of patients investigated for suspected AD, as it provides greater changes in diagnosis and diagnostic confidence. Trial registration: EudraCT no.: 2014-005389-31.
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- 2020
7. The Italian Dystonia Registry: rationale, design and preliminary findings
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Giovanni Defazio, Roberto Ceravolo, Maria Concetta Altavista, Giovanni Fabbrini, Alberto Albanese, Marcello Esposito, Marco Aguggia, Ruggero Bacchin, Maurizio Zibetti, L. Polidori, Maria Rosaria Mazza, Nicola Tambasco, Giovanni Cossu, Antonio Pisani, E Unti, Roberta Arca, Marcello Romano, Paolo Girlanda, Martina Petracca, Maria Cotelli, Michele Tinazzi, Giovanni Abbruzzese, Anna Rita Bentivoglio, Francesca Morgante, Gina Ferrazzano, Roberta Pellicciari, Roberto Eleopra, Laura Bertolasi, Cesa Scaglione, Luca Magistrelli, Angelo Fabio Gigante, Rocco Liguori, Nicola Modugno, Christian Lettieri, Salvatore Misceo, M. Coletti Moja, Alfredo Berardelli, Francesco Bono, Giovanna Squintani, Laura Avanzino, Silvio Peluso, Defazio, Giovanni, Esposito, M., Abbruzzese, G., Scaglione, C.L., Fabbrini, G., Ferrazzano, G., Peluso, S., Pellicciari, R., Gigante, A.F., Cossu, G., Arca, R., Avanzino, L., Bono, F., Mazza, M.R., Bertolasi, L., Bacchin, R., Eleopra, R., Lettieri, C., Morgante, F., Altavista, M.C., Polidori, L., Liguori, R., Misceo, S., Squintani, G., Tinazzi, M., Ceravolo, R., Unti, E., Magistrelli, L., Coletti Moja, M., Modugno, N., Petracca, M., Tambasco, N., Cotelli, M.S., Aguggia, M., Pisani, A., Romano, M., Zibetti, M., Bentivoglio, A.R., Albanese, A., Girlanda, P., Berardelli, A., Defazio, G., Scaglione, C. L., Gigante, A. F., Mazza, M. R., Altavista, M. C., Cotelli, M. S., and Bentivoglio, A. R.
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0301 basic medicine ,Male ,Pediatrics ,Movement disorders ,Epidemiology ,Severity of Illness Index ,0302 clinical medicine ,Retrospective Studie ,80 and over ,Cervical dystonia ,Registries ,Age of Onset ,Dystonia ,Aged, 80 and over ,education.field_of_study ,General Medicine ,Middle Aged ,Natural history ,Risk factors ,2708 ,Neurology (clinical) ,Psychiatry and Mental Health ,Italy ,Cohort ,Disease Progression ,Female ,Settore MED/26 - Neurologia ,medicine.symptom ,Human ,Adult ,medicine.medical_specialty ,congenital, hereditary, and neonatal diseases and abnormalities ,Blepharospasm ,Population ,Aged ,Humans ,Retrospective Studies ,Risk Factors ,Young Adult ,Dermatology ,03 medical and health sciences ,medicine ,otorhinolaryngologic diseases ,education ,business.industry ,medicine.disease ,nervous system diseases ,030104 developmental biology ,Physical therapy ,Etiology ,Risk factor ,business ,030217 neurology & neurosurgery - Abstract
The Italian Dystonia Registry is a multicenter data collection system that will prospectively assess the phenomenology and natural history of adult-onset dystonia and will serve as a basis for future etiological, pathophysiological and therapeutic studies. In the first 6 months of activity, 20 movement disorders Italian centres have adhered to the registry and 664 patients have been recruited. Baseline historical information from this cohort provides the first general overview of adult-onset dystonia in Italy. The cohort was characterized by a lower education level than the Italian population, and most patients were employed as artisans, builders, farmers, or unskilled workers. The clinical features of our sample confirmed the peculiar characteristics of adult-onset dystonia, i.e. gender preference, peak age at onset in the sixth decade, predominance of cervical dystonia and blepharospasm over the other focal dystonias, and a tendency to spread to adjacent body parts, The sample also confirmed the association between eye symptoms and blepharospasm, whereas no clear association emerged between extracranial injury and dystonia in a body site. Adult-onset dystonia patients and the Italian population shared similar burden of arterial hypertension, type 2 diabetes, coronary heart disease, dyslipidemia, and hypothyroidism, while hyperthyroidism was more frequent in the dystonia population. Geographic stratification of the study population yielded no major difference in the most clinical and phenomenological features of dystonia. Analysis of baseline information from recruited patients indicates that the Italian Dystonia Registry may be a useful tool to capture the real world clinical practice of physicians that visit dystonia patients.
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- 2017
8. Spinal infection multidisciplinary management project (SIMP): from diagnosis to treatment guideline
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F. Facchini, Giovanni Barbanti-Brodano, Fabio Tumietto, R. Bacchin, Cristina Nanni, Luca Boriani, Eugenio Rimondi, Pierluigi Viale, Ugo Albisinni, S Bonarelli, Stefano Fanti, Stefano Bandiera, Simone Colangeli, Alessandro Gasbarrini, Eleonora Zamparini, Rosanna Ciminari, Riccardo Ghermandi, L. Babbi, Alessandro Corghi, Vincenzo Allegri, A. Morigi, M. Difiore, Francesco Cristini, Maria Cristina Malaguti, Stefano Boriani, J. Frugiuele, Giada Rorato, G. Marinacci, Luca Amendola, Silvia Terzi, Caterina Salvadori, Gasbarrini A, Boriani L, Nanni C, Zamparini E, Rorato G, Ghermandi R, Salvadori C, Allegri V, Bandiera S, Barbanti-Brodano G, Colangeli S, Corghi A, Terzi S, Babbi L, Amendola L, Cristini F, Marinacci G, Tumietto F, Ciminari R, Malaguti MC, Rimondi E, Difiore M, Bacchin R, Facchini F, Frugiuele J, Morigi A, Albisinni U, Bonarelli S, Fanti S, Viale P, and Boriani S
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Spondylodiscitis ,Adult ,Male ,medicine.medical_specialty ,Discitis ,Immunology ,Guidelines as Topic ,Young Adult ,Multidisciplinary approach ,Fluorodeoxyglucose F18 ,Antibiotic therapy ,Immunology and Allergy ,Medicine ,Vertebral osteomyelitis ,Humans ,Medical physics ,Prospective Studies ,Prospective cohort study ,Aged ,Pharmacology ,Aged, 80 and over ,business.industry ,Osteomyelitis ,Extremely Helpful ,Guideline ,Middle Aged ,medicine.disease ,Bone Diseases, Infectious ,Magnetic Resonance Imaging ,Spine ,Surgery ,Anti-Bacterial Agents ,Positron-Emission Tomography ,Female ,Spinal Diseases ,spondylodiscitis ,Radiopharmaceuticals ,business ,Tomography, X-Ray Computed - Abstract
Spine infections require a multidisciplinary approach to be treated and solved. A guide line to drive physicians in the deep complexity of such a disease is extremely helpful. SIMP suggests a flow-chart built up on clear concepts such as right and well managed antibiotic therapy, sound stability of the spine, correct and smart use of the standard and functional imaging techniques, such as f18 FDG PET/CT. In 16 months a total of 41 patients have been treated for spondylodiscitis, discitis and vertebral osteomyelitis by our team of physicians and 25 patients have been enrolled in a prospective study whose target is the assessment of the SIMP flow-chart and of every single aspect that characterize it.
- Published
- 2011
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