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Objective Eikenella corrodens is a slow-growing, fastidious, non-motile, facultative anaerobic, Gram-negative bacillus that is commonly found in the human oropharynx. Although many cases have been reported in the adult population, only few cases of brain abscesses caused by E.corrodens have been reported in children so far. Methods Here, we reported the case of a 29-month-old female with complaints of weakness in the right leg twice in the past 3 weeks. Imaging studies revealed a brain abscess in the left parietofrontal lobe. The patient underwent surgery for abscess drainage, microbiological samples were obtained and empirical antibiotic treatment was started. Abscess culture showed the growth of E.corrodens. The bacteria were found to be sensitive to ceftriaxone; hence, the therapy was continued for 46 days with ceftriaxone. A final computed tomography showed the resolution of the abscess. The patient's clinical condition improved and she was discharged without any sequelae. Conclusion Brain abscess should be considered when patients present with neurological deficits. As far as we know, there are only six reported cases of brain abscesses only due to E.corrodens in the pediatric population. Since it is a slow-growing pathogen, early diagnosis and treatment are crucial for patient survival. This case supports the combination of surgical drainage and antibiotics for treatment.

Tuberculosis is a common problem in Turkey, and cutaneous tuberculosis is a rare form of extrapulmonary tuberculosis. Herein, the authors describe a case of cutaneous tuberculosis (lupus vulgaris) occurring after contact with a sheep.A 15-year-old boy was admitted to Marmara University School of Medicine Pendik Training and Research Hospital (Istanbul, Turkey) with delayed wound healing on the left index finger and left axillary lymphadenopathy. His medical history was unremarkable except for a wound incurred when he slaughtered a sheep 3 months before. One month after this injury, the patient developed enlargement of the left axillary lymph node on the side of the wounded extremity, and the wound turned a dark black color. The biopsy specimens obtained from the wounded skin and lymph nodes showed granulomatous reaction, but acid-fast bacilli (AFB) could not be shown with Ehrlich-Ziehl Neelsen staining. The patient tested positive in an interferon-gamma release assay. Computerized tomography scans of the thorax were normal, and early morning gastric lavage specimen was negative for AFB. The wound and axillary lymphadenopathy disappeared after institution of anti-tuberculosis therapy.Tuberculosis infection must be considered in chronic skin lesions with granulomatous reaction occurring in countries with high prevalence of tuberculosis.

Purpose: Human bocavirus (HBoV) is a recently discovered virus which is a member of Parvoviridae family. It is mostly detected in respiratory tract and stool specimens in pediatric patients with the diagnosis of acute respiratory tract infections and gastroenteritis, respectively. Material and Methods: Hospitalized children aged 1-56 months with the diagnosis of lower respiratory tract infection (LRTI) were included in this prospective study between February 1st 2009 and May 21st 2009. HBoV DNA was investigated by PCR method. A questionarrie form was applied for all of the patients. Written informed consent of a parent or legal guardian was requiredResults: Among the total of 120 hospitalized children who were investigated for HBoV the mean age was 9.9 months (1-56 months). HBoV DNA PCR in nasopharyngeal swabs was positive in 8 (6.7%) of 120 patients. In HBoV (+) lower respiratory tract infection group, to have an ill subling with similar symptoms and number of sublings (≥3 or more) were found to be risk factors. In HBoV (+) group serum level of C-reactive protein was significantly lower than HBoV (-) group. Conclusion: The clinical spectrum of HBoV infection ranges from no symptoms or mild respiratory symptoms to severe acute respiratory disease. Since there is lack of data investigating the frequency of HBoV respiratory tract infections in our region, our study has importance for providing new data., Amaç: İnsan Bocavirüsü (HBoV) Parvoviridae ailesinden yeni keşfedilmişbir virüstür. Çoğunlukla çocuk hastalarda solunum yolu ve dışkı örneklerindetespit edilir ve sırasıyla solunum yolu enfeksiyonlarına ve gastroenterittablosuna neden olur.Gereç veYöntem: 1 Şubat 2009- 21 Mayıs 2009 tarihleriarasında alt solunum yolu enfeksiyonu (ASYE) nedeniyle hastaneye yatırılan,yaşları 1-59 ay arasında değişen 120 çocuk bu prospektif çalışmaya dahiledildi. Hastaların solunum örneklerindenPCR yöntemi ile HBoV DNA’sı araştırıldı. Tüm hastalara risk faktörlerinibelirlemek amacıyla anket uygulandı. Çocukların ailelerinden ya da yasalbakıcılarından yazılı onam formu alındı.Bulgular: Çalışmaya alınan hastaların yaş ortalaması 9.9 ay(1-56 ay) idi. 120 hastanın 8 (%6.7)’inde nazofarengeal aspirat örneğinde PCRyöntemiyle bakılan HBoV DNA pozitif olarak bulundu. HBoV (+) alt solunum yoluenfeksiyonu grubunda, benzer semptomlara sahip kardeşe sahip olmak ve kardeş sayısının³3 ya da fazlaolması risk faktörleri olarakbelirlendi. HBoV (+) alt solunum yolu enfeksiyonu grubunda HBoV (-) alt solunumyolu enfeksiyonu grubuna göre serum C-reaktif protein (CRP) değerleri anlamlıolarak düşük bulundu. Sonuç: HBoVile enfeksiyon bulguları, hiçbir klinik semptomun olmamasından ciddi akutsolunum yolu enfeksiyonlarına kadar değişiklik gösterebilmektedir. Yenikeşfedilmiş bir virüs olması nedeniyle patojenitesi ve enfeksiyon için riskfaktörlerini araştıran daha çok çalışmaya ihtiyaç vardır. Bölgemizde bu konuile ilgili çok veri olmaması nedeniyle, çalışmamızın önemli bir kaynak olduğunudüşünmekteyiz

The rate of infection after a human bite is 10%-30%. Streptococcus spp. are the most common pathogens that may cause serious infections, such as necrotizing fasciitis. The authors describe a 5-year-old girl admitted to the emergency room with cellulitis due to S. pyogenes after human bites. She presented with fever and pain in her left arm, and her medical history revealed a human bite by her cousin on the arm 3 days prior. The wound culture yielded S. pyogenes. She was successfully treated with intravenous ampicillin-sulbactam regimen. S. pyogenes may cause serious wound infections following human bites. In such cases, the patient should be closely followed. Chemoprophylaxis should be initiated in an appropriate clinical setting to prevent secondary bacterial infections. This case was first reported as cellulitis due to S. pyogenes after a human bite.