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1. Valutazione della variazione temporale del rischio di mesotelioma e di tumore del polmone nelle coorti di esposti ad amianto per lavoro in Italia

Author

Magnani, Corrado, Ancona, Laura, Baldassarre, Antonio, Bressan, Vittoria, Cena, Tiziana, Chellini, Elisabetta, Cuccaro, Francesco, Ferrante, Daniela, Legittimo, Patrizia, Luberto, Ferdinando, Marinaccio, Alessandro, Mattioli, Stefano, Menegozzo, Simona, Merler, Enzo, Miligi, Lucia, Mirabelli, Dario, Musti, Marina, Oddone, Enrico, Pavone, Venere, Perticaroli, Patrizia, Pettinari, Aldo, Pirastu, Roberta, Ranucci, Alessandra, Romeo, Elisa, Sala, Orietta, Scarnato, Corrado, Silvestri, Stefano, Curti, Stefania, Magnani, Corrado, Ancona, Laura, Baldassarre, Antonio, Bressan, Vittoria, Cena, Tiziana, Chellini, Elisabetta, Cuccaro, Francesco, Ferrante, Daniela, Legittimo, Patrizia, Luberto, Ferdinando, Marinaccio, Alessandro, Mattioli, Stefano, Menegozzo, Simona, Merler, Enzo, Miligi, Lucia, Mirabelli, Dario, Musti, Marina, Oddone, Enrico, Pavone, Venere, Perticaroli, Patrizia, Pettinari, Aldo, Pirastu, Roberta, Ranucci, Alessandra, Romeo, Elisa, Sala, Orietta, Scarnato, Corrado, Silvestri, Stefano, [.., Curti, Stefania, and ]

Subjects
Male, Mesothelioma, Lung Neoplasms, Epidemiology, Environmental and Occupational Health, Asbestosi, Public Health, Environmental and Occupational Health, Socio-culturale, Ambientale, Asbesto, Asbestos, Occupational Disease, Lung Neoplasm, Occupational Diseases, Economica, Italy, Occupational Exposure, Asbestosis, Humans, Female, Public Health, Human
Abstract

This study aims at investigating, in asbestos exposed workers, the time trend of their risk of mesothelioma and of other neoplasm after very long latency and after the cessation of asbestos exposure. We pooled a large number of Italian cohorts of asbestos workers and updated mortality follow-up. The pool of data for statistical analyses includes 51,988 workers, of which 6,058 women: 54.2% was alive at follow-up, 42.6% was dead, and 2.8%was lost. Cause of death is known for 94.3%: 2,548 deaths from lung cancer, 748 frompleural cancer, 173 fromperitoneal cancer, and 434 from asbestosis. An exposure index is being developed to compare the different cohorts. Data analysis is in progress. This study will have the size for analysing not only time trends in mesothelioma, but also the occurrence of rarer diseases and cancer specific mortality in women.

Published
2016

2. Airports and air quality: A critical synthesis of the literature | Aeroporti e qualità dell'aria: Una sintesi critica della letteratura scientifica

Author

Cattani, Giorgio, Di Menno Di Bucchianico, Alessandro, Gaeta, Alessandra, Romano, Daniela, Fontana, Luca, Iavicoli, Ivo, Ancona, Carla, Ancona, Laura, Badaloni, Chiara, Cesaroni, Giulia, Bucci, Simone, Golini, Martina N., Mataloni, Francesca, Morciano, Claudio, Salatino, Chelo G., Zirro, Eleonora, Forastiere, Francesco, Barberini, Silvia, Bignardi, Gianmario, Bolignano, Andrea, Briotti, Valerio, Caleprico, Roberta, Damizia, Sesto, Fabozzi, Tina, Piatti, Raffaele, Troiano, Francesco, Sozzi, Roberto, Caricchia, Anna Maria, De Lauretis, Riccardo, Angelini, Francesco, Barnaba, Francesca, Costabile, Francesca, Gobbi, Gian Paolo, Inglessis, Marco, Tancredi, Francesco, Amadasi, Claudia, Cestari, Laura, Dorio, Roberta, Palazzi, Barbara, Zangrando, Dorelia, Simonato, Lorenzo, Sepulcri, Daniele, Arcadi, Celestina, Bandroco, Luisa, Barra, Graziella, Bellone, Fulvia, Carnà, Paolo, Casu, Pierina, Conchedda, Maria, De Fano, Carmela, Di Gilio, Piera, Macario, Antonella, Peritore, Maria, Sapetti, Stefania, Signorile, Luisa, Tempia, Vilma, Ottino, Marina, Chiusolo, Monica, Fogola, Jacopo, Cadum, Ennio, Camerino, Donatella, Consonni, Dario, Pesatori, Angela, Bertazzi, Pier Alberto, Ferri, Caterina, Minniti, Caterina, Nanni, Maddalena, Petri, Davide, Vigotti, Maria Angela, Licitra, Gaetano, Ascari., Elena, Antoniotti, Maria Chiara, Balconi, Lorena, Bonarrigo, Domenico, Stefani, Cristina Degli, Esposito, Aniello, Gambino, Maria, Speziali, Sabina, Pisani, Salvatore, Angius, Silvana, Galbusera, Emanuele, Maggi, Paola, and Pollini, Roberta

Subjects
Models, Air quality, Ground measurements, Airport
Abstract

This work reviewed existing literature on airport related activities that could worsen surrounding air quality; its aim is to underline the progress coming from recent-year studies, the knowledge emerging from new approaches, the development of semi-empiric analytical methods as well as the questions still needing to be clarified. To estimate pollution levels, spatial and temporal variability, and the sources relative contributions integrated assessment, using both fixed point measurement and model outputs, are needed. The general picture emerging from the studies was a non-negligible and highly spatially variable (within 2-3 km from the fence line) airport contribution; even if it is often not dominant compared to other concomitant pollution sources. Results were highly airport-specific. Traffic volumes, landscape and meteorology were the key variables that drove the impacts. Results were thus hardly exportable to other contexts. Airport related pollutant sources were found to be characterized by unusual emission patterns (particularly ultrafine particles, black carbon and nitrogen oxides during take-off); high time-resolution measurements allow to depict the rapidly changing take-off effect on air quality that could not be adequately observed otherwise. Few studies used high time resolution data in a successful way as statistical models inputs to estimate the aircraft take-off contribution to the observed average levels. These findings should not be neglected when exposure of people living near airports is to be assessed.

Published
2014

3. Health Impact Assessment of airport noise on people living nearby six Italian airports

Author

Ancona, Carla, Golini, Martina Nicole, Mataloni, Francesca, Camerino, Donatella, Chiusolo, Monica, Licitra, Gaetano, Ottino, Marina, Pisani, Salvatore, Cestari, Laura, Vigotti, Maria Angela, Davoli, Marina, Forastiere, Francesco, Ancona, Laura, Badaloni, Chiara, Cesaroni, Giulia, Bucci, Simone, Morciano, Claudio, Salatino, Chelo G., Zirro, Eleonora, Barberini, Silvia, Bignardi, Gianmario, Bolignano, Andrea, Briotti, Valerio, Caleprico, Roberta, Damizia, Sesto, Fabozzi, Tina, Piatti, Raffaele, Troiano, Francesco, Sozzi, Roberto, Caricchia, Anna Maria, De Lauretis, Riccardo, Di Menno Di Bucchianico, Alessandro, Gaeta, Alessandra, Romano, Daniela, Cattani, Giorgio, Angelini, Francesco, Barnaba, Francesca, Costabile, Francesca, Gobbi, Gian Paolo, Fontana, Luca, Iavicoli, Ivo, Inglessis, Marco, Tancredi, Francesco, Amadasi, Claudia, Dorio, Roberta, Palazzi, Barbara, Zangrando, Dorelia, Simonato, Lorenzo, Sepulcri, Daniele, Arcadi, Celestina, Bandroco, Luisa, Barra, Graziella, Bellone, Fulvia, Carnà, Paolo, Casu, Pierina, Conchedda, Maria, De Fano, Carmela, Di Gilio, Piera, Macario, Antonella, Peritore, Maria, Sapetti, Stefania, Signorile, Luisa, Tempia, Vilma, Fogola, Jacopo, Cadum, Ennio, Consonni, Dario, Pesatori, Angela, Bertazzi, Pier Alberto, Ferri, Caterina, Minniti, Caterina, Nanni, Maddalena, Petri, Davide, Ascari, Elena, Antoniotti, Maria Chiara, Balconi, Lorena, Bonarrigo, Domenico, Stefani, Cristina Degli, Esposito, Aniello, Gambino, Maria, Speziali, Sabina, Angius, Silvana, Galbusera, Emanuele, Maggi, Paola, Pollini, Roberta, Ancona, C., Golini, M. N., Mataloni, F., Camerino, D., Chiusolo, M., Licitra, G., Ottino, M., Pisani, S., Cestari, L., Vigotti, M. A., Davoli, M., Forastiere, F., Ancona, L., Badaloni, C., Cesaroni, G., Bucci, S., Morciano, C., Salatino, C. G., Zirro, E., Barberini, S., Bignardi, G., Bolignano, A., Briotti, V., Caleprico, R., Damizia, S., Fabozzi, T., Piatti, R., Troiano, F., Sozzi, R., Caricchia, A. M., De Lauretis, R., Di Menno Di Bucchianico, A., Gaeta, A., Romano, D., Cattani, G., Angelini, F., Barnaba, F., Costabile, F., Gobbi, G. P., Fontana, L., Iavicoli, Ivo, Inglessis, M., Tancredi, F., Amadasi, C., Dorio, R., Palazzi, B., Zangrando, D., Simonato, L., Sepulcri, D., Arcadi, C., Bandroco, L., Barra, G., Bellone, F., Carna, P., Casu, P., Conchedda, M., De Fano, C., Di Gilio, P., Macario, A., Peritore, M., Sapetti, S., Signorile, L., Tempia, V., Fogola, J., Cadum, E., Consonni, D., Pesatori, A., Bertazzi, P. A., Ferri, C., Minniti, C., Nanni, M., Petri, D., Ascari, E., Antoniotti, M. C., Balconi, L., Bonarrigo, D., Stefani, C. D., Esposito, A., Gambino, M., Speziali, S., Angius, S., Galbusera, E., Maggi, P., and Pollini, R.

Subjects
Annoyance, Health impact assessment, Hypertension, Sleep disturbances, Aircraft noise
Abstract

BACKGROUND: aircraft noise has been associated with several health effects. Because of the great success of low-cost flights, small airports have been turned into international airports thus exposing nearby residents to an increase in noise levels and potential disturbances and health disorders. OBJECTIVE: to estimate the exposure levels and evaluate the health impact of aircraft noise on residents nearby six airports in Italy (Rome: Ciampino; Milan: Linate and Malpensa; Pisa; Turin; Venice) focusing on hypertension, acute myocardial infarction (AMI), annoyance and sleep disturbances. METHODS: residents in the local Municipalities considered at 31.12.2010 were included in the study and their addresses were geocoded. Aircraft noise exposure in 2011 was defined using the Integrated Noise Model linked to each participant s address. Lden (55dB were considered: 55,915 (76.3%) were exposed to 55-60 dB; 16,562 (22.6%) to 60-65 dB; 795 (1.2%) to 65-70 dB. Exposure to aircraft noise levels above 55 dB was estimated to be responsible each year of 4,607 (95%CI 0-9,923) additional cases of hypertension; 3.4 (95%CI 0-10.7) cases of AMI; 9,789 (95%CI 6,895-11,962) cases of annoyance; 5,084 (95%CI 1,894-10,509) cases of sleep disturbances. CONCLUSIONS: a significant impact of airport noise on the health of residents nearby six Italian airports was estimated. Epidemiological evaluation and noise mitigation measures should be introduced to protect the health of residents.

Published
2014

4. Inquinamento atmosferico in un'area urbana limitrofa all'aeroporto di Roma-Ciampino

Author

Di Menno di Bucchianico, Alessandro, Cattani, Giorgio, Gaeta, Alessandra, Caricchia, Anna Maria, Troiano, Francesco, Sozzi, Roberto, Bolignano, Andrea, Sacco, Fabrizio, Damizia, Sesto, Barberini, Silvia, Caleprico, Roberta, Fabozzi, Tina, Ancona, Carla, Ancona, Laura, Cesaroni, Giulia, Forastiere, Francesco, Gobbi, Gian Paolo, Costabile, Francesca, Angelini, Federico, Barnaba, Francesca, Inglessis, Marco, Tancredi, Francesco, Palumbo, Lorenzo, Fontana, Luca, Bergamaschi, Antonio, and Iavicoli, Ivo

Published
2014

5. Time trend in mesothelioma and lung cancer risk in asbestos workers in Italy

Author

Magnani, Corrado, Ancona, Laura, Baldassarre, Antonio, Bressan, Vittoria, Cena, Tiziana, Chellini, Elisabetta, Cuccaro, Francesco, Ferrante, Daniela, Legittimo, Patrizia, Ferdinando Luberto, Marinaccio, Alessandro, Mattioli, Stefano, Menegozzo, Simona, Merler, Enzo, Miligi, Lucia, Mirabelli, Dario, Musti, Marina, Oddone, Enrico, Pavone, Venere, Perticaroli, Patrizia, Pettinari, Aldo, Pirastu, Roberta, Ranucci, Alessandra, Romeo, Elisa, Sala, Orietta, Scarnato, Corrado, and Silvestri, Stefano

6. Italian pool of asbestos workers cohorts: Mortality trends of asbestos-related neoplasms after long time since first exposure

Author

Simona Menegozzo, Dario Mirabelli, Francesco Cuccaro, Orietta Sala, Francesco Barone-Adesi, Daniela Ferrante, Vittoria Bressan, Lucia Miligi, Alessandro Marinaccio, Aldo Pettinari, Corrado Magnani, Paolo Girardi, Enzo Merler, Elisabetta Chellini, Venere Pavone, Alessandra Ranucci, Enrico Oddone, Patrizia Legittimo, Stefano Mattioli, Corrado Scarnato, Stefano Silvestri, Sara Tunesi, Laura Ancona, Patrizia Perticaroli, Roberta Pirastu, Marina Musti, Antonio Baldassarre, Tiziana Cena, Giuseppe Gorini, Elisa Romeo, Ferdinando Luberto, Ferrante, Daniela, Chellini, Elisabetta, Merler, Enzo, Pavone, Venere, Silvestri, Stefano, Miligi, Lucia, Gorini, Giuseppe, Bressan, Vittoria, Girardi, Paolo, Ancona, Laura, Romeo, Elisa, Luberto, Ferdinando, Sala, Orietta, Scarnato, Corrado, Menegozzo, Simona, Oddone, Enrico, Tunesi, Sara, Perticaroli, Patrizia, Pettinari, Aldo, Cuccaro, Francesco, Mattioli, Stefano, Baldassarre, Antonio, Barone-Adesi, Francesco, Cena, Tiziana, Legittimo, Patrizia, Marinaccio, Alessandro, Mirabelli, Dario, Musti, Marina, Pirastu, Roberta, Ranucci, Alessandra, Magnani, Corrado, [.., Curti, Stefania, and ]

Subjects
Male, Mesothelioma, Occupational cancer, Lung Neoplasms, Asbestosis, medicine.disease_cause, Cohort Studies, Economica, 0302 clinical medicine, Cause of Death, PLEURAL MESOTHELIOMA, TEXTILE WORKERS, Pleural Neoplasm, Lung, Peritoneal Neoplasms, Cause of death, LARYNGEAL-CANCER-MORTALITY, RISK, Ovarian Neoplasms, Asbestosi, Middle Aged, peritoneum, 030210 environmental & occupational health, Asbestos cement, Occupational Diseases, pleura, Italy, 030220 oncology & carcinogenesis, malignant mesothelioma, Female, Public Health, Peritoneal Neoplasm, FIBERS, Carcinogen, Cohort study, Human, Adult, medicine.medical_specialty, Pleural Neoplasms, MODELS, Socio-culturale, Asbesto, Asbestos, Settore MED/01 - Statistica Medica, CEMENT WORKERS, 03 medical and health sciences, LUNG-CANCER, asbestos, occupational cancer, ovary, Internal medicine, Occupational Exposure, medicine, Humans, METAANALYSIS, Aged, LARYNGEAL-CANCER-MORTALITY, PLEURAL MESOTHELIOMA, TEXTILE WORKERS, LUNG-CANCER, FOLLOW-UP, CEMENT WORKERS,MODELS, RISK, METAANALYSIS, FIBERS, business.industry, Construction Materials, Ovarian Neoplasm, Environmental and Occupational Health, Mesothelioma, Malignant, Ovary, Public Health, Environmental and Occupational Health, Ambientale, medicine.disease, Surgery, Construction Material, Lung Neoplasm, Occupational Disease, Carcinogens, Cohort Studie, FOLLOW-UP, Ovarian cancer, business
Abstract

Objective Asbestos is a known human carcinogen, with evidence for malignant mesothelioma (MM), cancers of lung, ovary, larynx and possibly other organs. MM rates are predicted to increase with a power of time since first exposure (TSFE), but the possible long-term attenuation of the trend is debated. The asbestos ban enforced in Italy in 1992 gives an opportunity to measure long-term cancer risk in formerly exposed workers. Methods Pool of 43 previously studied Italian asbestos cohorts (asbestos cement, rolling stock, shipbuilding), with mortality follow-up updated to 2010. SMRs were computed for the 1970–2010 period, for the major causes, with consideration of duration and TSFE, using reference rates by age, sex, region and calendar period. Results The study included 51 801 subjects (5741 women): 55.9% alive, 42.6% died (cause known for 95%) and 1.5% lost to follow-up. Mortality was significantly increased for all deaths (SMR: men: 1.05, 95% CI 1.03 to 1.06; women: 1.17, 95% CI to 1.12 to 1.22), all malignancies combined (SMR: men: 1.17, 95% CI to 1.14 to 1.20; women: 1.33, 95% CI 1.24 to 1.43), pleural and peritoneal malignancies (SMR: men: 13.28 and 4.77, 95% CI 12.24 to 14.37 and 4.00 to 5.64; women: 28.44 and 6.75, 95% CI 23.83 to 33.69 and 4.70 to 9.39), lung (SMR: men: 1.26, 95% CI 1.21 to 1.31; women: 1.43, 95% CI 1.13 to 1.78) and ovarian cancer (SMR=1.38, 95% CI 1.00 to 1.87) and asbestosis (SMR: men: 300.7, 95% CI 270.7 to 333.2; women: 389.6, 95% CI 290.1 to 512.3). Pleural cancer rate increased during the first 40 years of TSFE and reached a plateau after. Discussion The study confirmed the increased risk for cancer of the lung, ovary, pleura and peritoneum but not of the larynx and the digestive tract. Pleural cancer mortality reached a plateau at long TSFE, coherently with recent reports.

Published
2017

7. Air pollution in an urban area nearby the Rome-Ciampino city airport

Author

Di Menno di Bucchianico A, Giorgio Cattani, Gaeta A, Am, Caricchia, Troiano F, Sozzi R, Bolignano A, Sacco F, Damizia S, Barberini S, Caleprico R, Fabozzi T, Ancona C, Ancona L, Cesaroni G, Forastiere F, Gp, Gobbi, Costabile F, Angelini F, Barnaba F, Inglessis M, Tancredi F, Palumbo L, Fontana L, Bergamaschi A, Iavicoli I, Di Menno di Bucchianico, Alessandro, Cattani, Giorgio, Gaeta, Alessandra, Caricchia, Anna Maria, Troiano, Francesco, Sozzi, Roberto, Bolignano, Andrea, Sacco, Fabrizio, Damizia, Sesto, Barberini, Silvia, Caleprico, Roberta, Fabozzi, Tina, Ancona, Carla, Ancona, Laura, Cesaroni, Giulia, Forastiere, Francesco, Gobbi, Gian Paolo, Costabile, Francesca, Angelini, Federico, Barnaba, Francesca, Inglessis, Marco, Tancredi, Francesco, Palumbo, Lorenzo, Fontana, Luca, Bergamaschi, Antonio, and Iavicoli, Ivo

Subjects
Air Pollutants, models, Settore MED/44 - MEDICINA DEL LAVORO, Airports, airport, Air Pollution, Rome, Urban Health, Aiport, air quality, ground measurements
Abstract

OBJECTIVES: to assess air pollution spatial and temporal variability in the urban area nearby the Ciampino International Airport (Rome) and to investigate the airport-related emissions contribute. DESIGN AND SETTING: the study domain was a 64 km2 area around the airport. Two fifteen-day monitoring campaigns (late spring, winter) were carried out. Results were evaluated using several runs outputs of an airport-related sources Lagrangian particle model and a photochemical model (the Flexible Air quality Regional Model, FARM). MAIN OUTCOME MEASURES: both standard and high time resolution air pollutant concentrations measurements: CO, NO, NO2, C6H6, mass and number concentration of several PM fractions. 46 fixed points (spread over the study area) of NO2 and volatile organic compounds concentrations (fifteen days averages); deterministic models outputs. RESULTS: standard time resolution measurements, as well as model outputs, showed the airport contribution to air pollution levels being little compared to the main source in the area (i.e. vehicular traffic). However, using high time resolution measurements, peaks of particles associated with aircraft takeoff (total number concentration and soot mass concentration), and landing (coarse mass concentration) were observed, when the site measurement was downwind to the runway. CONCLUSIONS: the frequently observed transient spikes associated with aircraft movements could lead to a not negligible contribute to ultrafine, soot and coarse particles exposure of people living around the airport. Such contribute and its spatial and temporal variability should be investigated when assessing the airports air quality impact.

Published
2014

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