175 results on '"Adnan Saithna"'
Search Results
2. Clinical Outcomes After Combined ACL and Anterolateral Ligament Reconstruction Versus Isolated ACL Reconstruction With Bone–Patellar Tendon–Bone Grafts: A Matched-Pair Analysis of 2018 Patients From the SANTI Study Group
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Charles Pioger, Lampros Gousopoulos, Graeme P. Hopper, Thais Dutra Vieira, Joao Pedro Campos, Abdo El Helou, Corentin Philippe, Adnan Saithna, and Bertrand Sonnery-Cottet
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Cohort Studies ,Rupture ,Anterior Cruciate Ligament Reconstruction ,Patellar Ligament ,Anterior Cruciate Ligament Injuries ,Matched-Pair Analysis ,Hamstring Tendons ,Humans ,Physical Therapy, Sports Therapy and Rehabilitation ,Orthopedics and Sports Medicine ,Autografts ,Bone-Patellar Tendon-Bone Grafting ,Bone-Patellar Tendon-Bone Grafts - Abstract
Background: Bone–patellar tendon–bone (BPTB) autografts are widely considered the standard for anterior cruciate ligament reconstruction (ACLR). Purpose/Hypothesis: The aims of this study were to compare the clinical outcomes after ACLR with gold standard BPTB autografts versus combined ACLR + anterolateral ligament reconstruction (ALLR) with hamstring tendon (HT) autografts at medium-term follow-up in a large series of propensity-matched patients. The hypothesis was that combined ACLR + ALLR with HT autografts would result in lower graft rupture rates and non–graft rupture-related reoperation rates. Study Design: Cohort study; Level of evidence, 3. Methods: Patients undergoing combined ACLR + ALLR using HT autografts between January 2003 and December 2019 were propensity matched in a 1:1 ratio to patients undergoing isolated ACLR using BPTB autografts. At the end of the study period, graft ruptures, contralateral knee injuries, and any other reoperations or complications after the index procedure were identified by a search of a prospective database and a review of medical records. Results: A total of 1009 matched pairs were included. The mean duration of follow-up was 101.3 ± 59.9 months. Patients in the isolated group were >3-fold more likely to have graft failure than those in the combined group (hazard ratio, 3.554 [95% CI, 1.744-7.243]; P = .0005). Patients aged 30 years (hazard ratio, 5.650 [95% CI, 1.834-17.241]; P = .0002). Additionally, there was a significantly higher reoperation rate after isolated ACLR than after combined ACLR + ALLR (20.5% vs 8.9%, respectively; P < .0001). The overall rate of subsequent contralateral ruptures was 9.1% after index surgery (isolated: 10.2%; combined: 8.0%; P = .0934), indicating that the risk profiles for both groups were similar. Conclusion: Patients who underwent isolated ACLR with BPTB autografts experienced significantly worse graft survivorship and overall reoperation-free survivorship compared with those who underwent combined ACLR + ALLR with HT autografts. The risk of graft ruptures was >3-fold higher in patients who underwent isolated ACLR using BPTB autografts.
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- 2022
3. Management of the Failed First Revision ACL Reconstruction: Clinical Outcomes of Nonsurgical Management Versus Second Revision ACL Reconstruction From the SANTI Group
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Thomas Fradin, Adnan Saithna, Ibrahim M. Haidar, Johnny Rayes, Abdo El Helou, Cedric Ngbilo, Charles Pioger, Thais Dutra Vieira, Graeme P. Hopper, and Bertrand Sonnery-Cottet
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Cohort Studies ,Reoperation ,Anterior Cruciate Ligament Reconstruction ,Knee Joint ,Anterior Cruciate Ligament Injuries ,Quality of Life ,Humans ,Physical Therapy, Sports Therapy and Rehabilitation ,Orthopedics and Sports Medicine - Abstract
Background: The optimum management strategy after failure of revision anterior cruciate ligament reconstruction (RACLR) is not clearly defined. The literature evaluating differences in outcomes between surgical and nonsurgical management is sparse. Purpose/Hypothesis: The purpose was to evaluate the outcomes of surgical versus nonsurgical management of failed first RACLR. It was hypothesized that the long-term clinical outcomes of second RACLR would be superior with respect to knee stability, return to sport, and patient-reported outcome measures when compared with nonsurgical treatment. Study Design: Cohort study; Level of evidence, 3. Methods: Patients who experienced failure of first RACLR were evaluated. All participants followed the same rehabilitation protocol regardless of whether they underwent nonsurgical treatment or a second RACLR. Follow-up comprised regular clinical review and a standardized telephone interview at the end of the study period. Patient-reported outcome measures were recorded at the final follow-up. Results: A total of 41 patients with a mean follow-up of 104 ± 52.7 months (range, 40-140 months) were evaluated. Of these, 31 underwent a second RACLR, and 10 patients chose nonsurgical treatment. There was a high rate of return to sport in both groups, but patients undergoing second RACLR had significantly better Tegner (6.35 vs 4.8; P = .012), Lysholm (88.5 vs 78.3; P = .0353), Knee injury and Osteoarthritis Outcome Score (KOOS) Quality of Life (72.6 vs 56.3; P = .0490), and KOOS Sport and Recreation scores (81.4 vs 62.5; P = .0033). Significantly more patients undergoing second RACLR achieved the Patient Acceptable Symptom State for KOOS Sport and Recreation than those who underwent nonsurgical management (74.2% vs 30%; P = .015). The most important predictor of failure to achieve a good/excellent Lysholm score in multivariate analysis was nonsurgical management ( P = .0095). Conclusion: Both second RACLR and nonsurgical management of failed first RACLR were associated with high rates of return to sport. However, second RACLR was associated with significantly better functional outcome scores with respect to Tegner, Lysholm, KOOS Quality of Life, and KOOS Sport and Recreation scores compared to nonsurgical management. In addition, nonsurgical treatment was the only significant predictor of failure to achieve a good/excellent Lysholm score at the final follow-up, and this was likely a function of inferior knee stability in that group.
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- 2022
4. Editorial Commentary: Lateral Extra-articular Procedures Concomitant to Anterior Cruciate Ligament Reconstruction Must Balance Clinical Efficacy and the Risk of Kinematic Restraint
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Jean-Romain Delaloye and Adnan Saithna
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Orthopedics and Sports Medicine - Published
- 2022
5. Combined Revision Anterior Cruciate Ligament and Anterolateral Ligament Reconstruction
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Graeme P. Hopper, Corentin Philippe, Abdo El Helou, Lampros Gousopoulos, Thomas Fradin, Thais Dutra Vieira, Adnan Saithna, and Bertrand Sonnery-Cottet
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Orthopedics and Sports Medicine - Abstract
There has been a substantial increase in the number of revision anterior cruciate ligament (ACL) reconstructions performed in the past decade. This Technical Note describes combined revision ACL and anterolateral ligament reconstruction using outside-in drilling, which avoids the need for 2-stage revision ACL reconstruction because it allows unconstrained anatomic placement.
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- 2022
6. The modern-day ACL surgeon's armamentarium should include multiple surgical approaches including primary repair, augmentation, and reconstruction: A letter to the Editor
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Sebastian Rilk, Adnan Saithna, Andrea Achtnich, Andrea Ferretti, Bertrand Sonnery-Cottet, Clemens Kösters, Craig R. Bottoni, Edoardo Monaco, Etienne Cavaignac, Georg Ahlbaeumer, Georg Brandl, Gordon M. Mackay, Harmen D. Vermeijden, Ignacio Dallo, J. Lee Pace, Jelle P. van der List, Jesús Rey Moggia, Jorge Chahla, Jorge Pablo Batista, Karl H. Frosch, Kristian N. Schneider, Patrick A. Smith, Rachel M. Frank, Roy A.G. Hoogeslag, Stefan Eggli, Wiemi A. Douoguih, Wolf Petersen, and Gregory S. DiFelice
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Orthopedics and Sports Medicine ,Surgery - Published
- 2023
7. Podium Presentation Title: Isolated Medial Meniscus Repairs are at Higher Risk of Failure Compared to Lateral Meniscus Tears
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Johnny Rayes, Adnan Saithna, Ibrahim Haidar, Thomas Fradin, Cedric Ngbilo, Thais Dutra Vieira, and Bertrand Sonnery-Cottet
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Orthopedics and Sports Medicine - Published
- 2023
8. Podium Presentation Title: Lateral Extra-Articular Procedures Significantly Reduce ACL Graft Rupture Rates in Elite Alpine Skiers
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Adnan Saithna, Sylvain Guy, Alessandro Carrozzo, Stephane Bulle, Thais Dutra Vieira, Jean-Marie Fayard, and Bertrand Sonnery-Cottet
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Orthopedics and Sports Medicine - Published
- 2023
9. Anterolateral Ligament Reconstruction Does Not Delay Functional Recovery, Rehabilitation, and Return to Sport After Anterior Cruciate Ligament Reconstruction: A Matched-Pair Analysis From the SANTI (Scientific ACL Network International) Study Group
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Marine Coquard, Alessandro Carrozzo, Adnan Saithna, Gregory Vigne, Meven Le Guen, Yann Fournier, Jean-Philippe Hager, Thais Dutra Vieira, and Bertrand Sonnery-Cottet
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recovery ,acl ,anterolateral ligament reconstruction ,all ,santi group ,rehabilitation ,return to sport ,Sports medicine ,Rehabilitation ,Public Health, Environmental and Occupational Health ,Physical Therapy, Sports Therapy and Rehabilitation ,Orthopedics and Sports Medicine ,RC1200-1245 - Abstract
Purpose: To determine whether the addition of an anterolateral ligament reconstruction (ALLR) resulted in delayed functional recovery (based on the Knee Santy Athletic Return to Sport [K-STARTS] score) at 6 months after anterior cruciate ligament reconstruction (ACLR). Methods: A retrospective analysis of prospectively collected data from consecutive patients who underwent an ACLR between September 2017 and December 2020 was conducted. Patients who received an isolated hamstring autograft (isolated ACLR group) were propensity matched in a 1:1 ratio to patients who received a hamstring autograft ACLR combined with an ALLR (ACLR-ALLR group). Outcome measures included the Tegner Activity Scale and the K-STARTS test—a validated composite return-to-sports test (including the Anterior Cruciate Ligament–Return to Sport After Injury scale, Qualitative Assessment of Single-Leg Landing tool, limb symmetry index, and ability to change direction using the Modified Illinois Change of Direction Test). Results: The study included 111 matched pairs. At 6 months postoperatively, there were no significant differences between groups in the overall K-STARTS score (65.4 for isolated ACLR vs 61.2 for ACLR-ALLR, P = .087) or the Tegner Activity Scale score (3.7 for isolated ACLR vs 3.8 for ACLR-ALLR, P = .45). In addition, an evaluation of the subscales of the K-STARTS score revealed no disadvantage across the domains of neuromuscular control, limb symmetry index, agility, or psychological readiness to return to sport when an ALLR was performed. Conclusions: The addition of ALLR at the time of ACLR does not delay functional recovery. Specifically, at 6 months postoperatively, there was no disadvantage in patients undergoing ALLR-ACLR, when compared with those undergoing isolated ACLR, with respect to neuromuscular control, limb symmetry indices (hop tests), agility, or psychological readiness to return to sport. Level of Evidence: Level III, retrospective comparative study.
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- 2022
10. ACL Revision Plus Lateral Extra-articular Procedure Results in Superior Stability and Lower Failure Rates Than Does Isolated ACL Revision But Shows No Difference in Patient-Reported Outcomes or Return to Sports
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Adnan, Saithna, Edoardo, Monaco, Alessandro, Carrozzo, Fabio, Marzilli, Silvia, Cardarelli, Benson, Lagusis, Giorgio, Rossi, Thais, Dutra-Vieira, Andrea, Ferretti, and Bertrand, Sonnery-Cottet
- Abstract
The aim of this systematic review was to determine whether comparative clinical studies demonstrate significant advantages of revision anterior cruciate ligament (ACL) reconstruction combined with a lateral extra-articular procedure (LEAP), with respect to graft rupture rates, knee stability, return to sport rates, and patient reported outcome measures (PROMS) when compared to isolated revision ACL reconstruction (RACLR).Systematic review was conducted in accordance with Preferred Reporting Items for Systematic ReviewsMeta-Analyses Guidelines. A PubMed search was conducted using the keywords "revision anterior cruciate ligament reconstruction" combined with any of the following additional terms, "lateral extra-articular tenodesis" OR "anterolateral ligament reconstruction" OR "Lemaire". All relevant comparative clinical studies were included. Key clinical data was extracted and evaluated.Eight comparative studies (seven level III studies and a one level IV study) were identified and included. Most studies reported more favorable outcomes with combined procedures with respect to failure rates (0% to 13% following RACLR+LEAP, and 4.4% to 21.4% following isolated RACLR), post-operative side-to-side AP laxity difference (1.3mm to 3.9mm following RACLR+LEAP and 1.8mm to 5.9mm following isolated RACLR), and high-grade pivot shift (0% to 11.1% following RACLR+LEAP and 10.2% to 23.8% in patients following isolated RACLR). There were no consistent differences between isolated and combined procedures with respect to return to sport or PROMS.This systematic review demonstrates that the addition of a LEAP to RACLR was associated with an advantage with respect to ACL graft failure rates and avoidance of high grade post-operative knee laxity across almost all included studies.IV, Systematic Review of level III to IV studies.
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- 2022
11. The Minimal Clinically Important Difference, Patient Acceptable Symptom State, and Clinical Outcomes of Anterior Cruciate Ligament Repair Versus Reconstruction: A Matched-Pair Analysis From the SANTI Study Group
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Alexandre Ferreira, Adnan Saithna, Alessandro Carrozzo, Sylvain Guy, Thais Dutra Vieira, Johannes Barth, and Bertrand Sonnery-Cottet
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Cohort Studies ,acl repair ,acl reconstruction ,Anterior Cruciate Ligament Injuries ,Matched-Pair Analysis ,Minimal Clinically Important Difference ,Humans ,Physical Therapy, Sports Therapy and Rehabilitation ,Orthopedics and Sports Medicine ,graft rupture ,return to sport ,Anterior Cruciate Ligament - Abstract
Background: There has been increasing interest in anterior cruciate ligament (ACL) repair because of theoretical advantages over ACL reconstruction; however, the contemporary literature has failed to provide high-quality evidence to demonstrate these advantages. Purpose: To compare the clinical and functional outcomes of ACL repair versus ACL reconstruction at a minimum follow-up of 2 years. Study Design: Cohort study; Level of evidence, 3. Methods: Patients who underwent ACL repair were propensity matched (based on demographics, time between injury and surgery, knee laxity parameters, presence of meniscal lesions, preoperative activity level, and sport participation), in a 1:1 ratio, to those who underwent ACL reconstruction during the same period. Isokinetic testing was used to evaluate strength deficits at 6 months postoperatively. Knee laxity parameters were evaluated at 12 months. Complications, return to sport, and patient-reported outcome scores were recorded at final follow-up. Results: In total, 75 matched pairs (150 patients) were evaluated. The repair group had significantly better mean hamstring muscle strength at 6 months compared with the reconstruction group (1.7% ± 12.2% vs −10.0% ± 12.8%, respectively; P < .0001). At a mean final follow-up of 30.0 ± 4.8 months, the repair group had a significantly better mean Forgotten Joint Score–12 (FJS-12) score compared with the reconstruction group (82.0 ± 15.1 vs 74.2 ± 21.7, respectively; P = .017). Noninferiority criteria were met for ACL repair, compared with ACL reconstruction, with respect to the subjective International Knee Documentation Committee score (86.8 ± 9.0 vs 86.7 ± 10.1, respectively; P < .0001) and side-to-side anteroposterior laxity difference (1.1 ± 1.4 vs 0.6 ± 1.0 mm, respectively; P < .0001). No significant differences were found for other functional outcomes or the pivot-shift grade. There were no significant differences in the rate of return to the preinjury level of sport (repair group: 74.7%; reconstruction group: 60.0%; P = .078). A significant difference was observed regarding the occurrence of ACL reruptures (repair group: 5.3%; reconstruction group: 0.0%; P = .045). Patients who experienced a failure of ACL repair were significantly younger than those who did not (26.8 vs 40.7 years, respectively; P = .013). There was no significant difference in rupture rates between the repair and reconstruction groups when only patients aged >21 years were considered (2.9% vs 0.0%, respectively; P = .157). The minimal clinically important difference and Patient Acceptable Symptom State (PASS) thresholds were defined for the ACL repair group. A significantly greater proportion of patients in the repair group achieved the PASS for the FJS-12 compared with their counterparts in the reconstruction group (77.3% vs 60.0%, respectively; P = .034). Conclusion: ACL repair was associated with some advantages over ACL reconstruction including superior hamstring muscle strength at 6 months and significantly better FJS-12 scores. However, the failure rate was significantly higher after ACL repair, and younger patients were particularly at risk.
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- 2022
12. Isolated ACL Reconstruction Versus ACL Reconstruction Combined With Lateral Extra-articular Tenodesis: A Comparative Study of Clinical Outcomes in Adolescent Patients
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Edoardo Monaco, Alessandro Carrozzo, Adnan Saithna, Fabio Conteduca, Alessandro Annibaldi, Fabio Marzilli, Marta Minucci, Bertrand Sonnery-Cottet, and Andrea Ferretti
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Adult ,Adolescent ,Anterior Cruciate Ligament Reconstruction ,Knee Joint ,acl ,graft failure ,Anterior Cruciate Ligament Injuries ,Tenodesis ,knee ,Physical Therapy, Sports Therapy and Rehabilitation ,ligaments ,Cohort Studies ,pediatric sports medicine ,anterior cruciate ligament reconstruction ,lateral extra-articular tenodesis ,Humans ,Orthopedics and Sports Medicine ,Child ,Retrospective Studies - Abstract
Background: Young patients undergoing anterior cruciate ligament (ACL) reconstruction (ACLR) are at a particularly high risk of graft ruptures compared with adults. Recent studies have demonstrated significant reductions in ACL graft rupture rates in high-risk adult populations when a lateral extra-articular procedure is performed, but comparative studies in pediatric and adolescent populations are currently lacking in the literature. Purpose/Hypothesis: The purpose of this study was to compare the clinical outcomes of isolated ACLR versus combined ACLR and lateral extra-articular tenodesis (LET) when using the Arnold-Coker modification of the MacIntosh procedure in early adolescent patients. The hypothesis was that combined procedures would be associated with a significantly reduced risk of graft ruptures. Study Design: Cohort study; Level of evidence, 3. Methods: A retrospective analysis of consecutive early adolescent patients who underwent ACLR using a hamstring tendon autograft with or without the Arnold-Coker modification of the MacIntosh procedure was conducted. Patients with ≥1 additional risk factors for a graft rupture were offered LET in addition to ACLR (pivot-shift grade 2 or 3, high level of sporting activity defined as Tegner activity score ≥7, participation in pivoting sports, and Segond fractures). Clinical outcomes including graft rupture rates, patient-reported outcome measure scores (Knee injury and Osteoarthritis Outcome Score and subjective International Knee Documentation Committee), knee stability, return-to-sports rates, reoperation rates, and complications were assessed. Comparisons between variables were assessed with the chi-square or Fisher exact test for categorical variables and the Student or Wilcoxon test for quantitative variables. Multivariate analyses were undertaken to evaluate risk factors for a graft rupture. Results: A total of 111 patients with a mean follow-up of 43.8 ± 17.6 months (range, 24-89 months) were included in the study; 40 patients underwent isolated ACLR, and 71 underwent ACLR + LET. The addition of LET to ACLR was associated with a significantly lower graft rupture rate compared with isolated ACLR (0.0% vs 15.0%, respectively; odds ratio, 15.91 [95% CI, 1.81-139.44]; P = .012). It was also associated with significantly better knee stability (pivot-shift grade 3: 0.0% vs 11.4%, respectively; P = .021) (side-to-side anteroposterior laxity difference >5 mm: 0.0% vs 17.1%, respectively; P = .003) and Tegner activity scores (7 vs 6, respectively; P = .010). There were no significant differences between the groups regarding the Patient Acceptable Symptom State for the patient-reported outcome measures, nor for any of the other outcome measures evaluated, and no differences in the rate of non–graft rupture related reoperations or complications. The ACLR + LET group exceeded the minimal clinically important difference with respect to the Tegner activity scale. Conclusion: In a retrospective comparative cohort study of adolescents, combined ACLR and LET was associated with a significantly lower graft rupture rate and no difference in non–graft rupture related reoperations or complications compared with isolated ACLR.
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- 2022
13. Clinical Outcomes of Combined Anterior Cruciate Ligament Reconstruction and Lateral Extra-articular Tenodesis Procedures in Skeletally Immature Patients: A Systematic Review From the SANTI Study Group
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Alessandro Carrozzo, Edoardo Monaco, Adnan Saithna, Alessandro Annibaldi, Sylvain Guy, Alexandre Ferreira, Thais Dutra Vieira, Andrea Ferretti, and Bertrand Sonnery-Cottet
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Pediatrics, Perinatology and Child Health ,Orthopedics and Sports Medicine ,General Medicine - Abstract
The treatment of anterior cruciate ligament (ACL) tears in the pediatric population has changed significantly in the past few decades. Pediatric patients who underwent ACL reconstruction (ACLR) have a high risk of rerupture of up to 32%. The addition of lateral extra-articular procedures [lateral extra-articular tenodesis (LET)], already shown to be effective in reducing the risk of rerupture in adults, may also be effective in pediatric patients. The purpose of this study was to systematically review the clinical outcomes of ACLR+LET tenodesis in pediatric patients.Data were collected from Pubmed, MEDLINE, Cochrane, and Scopus Databases according to the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines. Studies reporting the clinical outcomes of ACLR+LET in the pediatric population using autograft, return to play, growth disturbances, failure rate, and surgical complications were included.A total of 5 studies comprising 381 pediatric patients were included. Three main surgical techniques with common features were used. The mean age of all pediatric patients in the included studies was 11.73 years (range, 5.6 to 16) with a mean follow-up of 50.1 months. The overall graft failure rate of the included studies was 4.65%. The return to play was 95.11%. The mean Lysholm score was 94.51 and the mean Pediatric International Knee Documentation Committee (Pedi-IKDC) was 93.39. In all, 1.9% of the patients had a coronal plane deformity and 0.8% had a limb length discrepancy. 4.6% of the patients had a contralateral ACL tear.A combined ACLR+LET in pediatric patients showed a graft failure ranging from 0% to 13.6% at a mean follow-up of 50.1 months. This low graft failure rate is consistent with ACLR+LET in adults. Further investigations are needed to validate these findings and the potential role of LET in reducing graft rupture rates in this population.Level IV-systematic review of level IV studies.
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- 2022
14. The Anterolateral Ligament Has Limited Intrinsic Healing Potential: A Serial, 3-Dimensional–Magnetic Resonance Imaging Study of Anterior Cruciate Ligament–Injured Knees From the SANTI Study Group
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Adnan Saithna, Camilo Partezani Helito, Bertrand Sonnery-Cottet, Koichi Muramatsu, and Thais Dutra Vieira
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Anterolateral ligament ,030222 orthopedics ,Anterior Cruciate Ligament Reconstruction ,Knee Joint ,medicine.diagnostic_test ,business.industry ,Anterior Cruciate Ligament Injuries ,Anterior cruciate ligament ,Physical Therapy, Sports Therapy and Rehabilitation ,Magnetic resonance imaging ,030229 sport sciences ,Anatomy ,Magnetic Resonance Imaging ,03 medical and health sciences ,0302 clinical medicine ,medicine.anatomical_structure ,medicine ,Humans ,Orthopedics and Sports Medicine ,Anterior Cruciate Ligament ,business - Abstract
Background:Recent imaging studies demonstrate that the anterolateral ligament (ALL) is frequently injured at the time of anterior cruciate ligament (ACL) rupture. The intrinsic healing potential of these injuries after ACL reconstruction (ACLR) has not been defined.Purpose/Hypothesis:The primary objective was to evaluate the rate and duration of the healing process of injured ALLs after ACLR using serial 3-dimensional magnetic resonance imaging (3D-MRI). The secondary objective was to investigate whether any patient, injury, or surgical factors influenced the healing rate. The hypothesis was that serial imaging would demonstrate that the ALL has limited healing potential.Study Design:Case series; Level of evidence, 4.Methods:Patients enrolled in the study underwent 3D-MRI (slice thickness 0.5 mm) preoperatively and at 1, 6, 12, and 24 months after ACLR. Three observers determined the grade of ALL injury according to the Muramatsu classification. Inter- and intraobserver reliabilities were calculated. The rates of injury and time points for healing were determined. Full healing was defined as a change from a preoperative Muramatsu grade of B or C (indicating partial or complete injury) to grade A (normal). Multivariate analysis was used to investigate the association of aforementioned factors with the risk of incomplete healing.Results:A total of 44 patients were enrolled in the study. Of them, 71.2% had an ALL injury on preoperative imaging. Overall, full healing of ALL injuries occurred at a rate of 3.2%, 15.2%, and 30.3% at 1, 6, and 12 months, respectively. There were no changes in the Muramatsu grade in any patient beyond 12 months postoperatively. None of the complete lesions demonstrated full healing, but the proportion of patients with a grade C injury decreased from 13.6% preoperatively to 4.5% at 12 months due to an improvement to grade B in 4 of 6 patients (66%). Inter- and intraobserver reliabilities of the classification system were almost perfect at 0.81-0.94 and 0.95-1.00, respectively. None of the potential risk factors investigated were predictive of an increased risk of nonhealing.Conclusion:ALL injuries occurred in the majority of ACL-injured knees. They had limited intrinsic healing potential, with only 30.3% healing by 12 months after ACLR. The process of healing took >6 months in half of the patients in whom it occurred. No new cases of full healing occurred beyond 12 months postoperatively. No significant risk factors for failure of full healing to occur were identified, but it is likely that this aspect of the study was underpowered.
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- 2021
15. Aucune différence dans les résultats cliniques et radiologiques après la fixation de fractures transversales de la rotule avec une fixation par une bandelette ou un cerclage métallique : une étude comparative rétrospective
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Adnan Saithna, Alessandro Annibaldi, Silvia Cardarelli, Andrea Ferretti, Andrea Del Duca, Edoardo Monaco, Alessandro Carrozzo, Giorgio Bruni, and Matthew Daggett
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medicine.medical_specialty ,business.industry ,Radiography ,Significant difference ,Outcome measures ,medicine.disease ,Surgery ,Suture (anatomy) ,medicine ,Orthopedics and Sports Medicine ,Malunion ,Clinical efficacy ,Complication ,business ,Fixation (histology) - Abstract
Introduction Several surgical techniques have been proposed for the treatment of patellar fractures. The aim of this study is to compare the clinical efficacy and complication rates of treatment using suture tape circumferential cerclage (STCC) and metallic wire circumferential cerclage (MWCC) for the surgical treatment of displaced transverse patellar fractures (TPFs). Hypothesis The hypothesis is that the use of the suture tape would be associated with a significantly lower rate of re-peration than metallic cerclage but no differences in other clinical outcomes. Patients and methods A retrospective comparative analysis of the clinical outcomes of consecutive patients undergoing fixation of TPFs with either MWCC or STCC between January 2017 and December 2018 was undertaken. All patients underwent evaluation with standardised radiographs at one, three, and six months after surgery to determine rates of union, non-union, loss of fixation and malunion. All patients underwent a final clinical evaluation at 18 months post-operatively to evaluate clinical scores and complications. Results A total of 26 patients were included in the study. Thirteen patients underwent STCC and 13 underwent MWCC. There were no complications in the STCC group. In the MWCC group, one patient underwent hardware removal at two months post-operatively due to painful prominence. There was no significant difference in reoperation rates between the STCC and MWCC groups (p = 1). There were no cases of non-union, malunion or loss of reduction throughout the series. At the final clinical follow-up of 18 months, there were no significant differences in KSS, KOOS or Bostman scores between the groups. Conclusion No significant differences were identified when comparing the clinical outcomes of fixation of AO/OTA 34C1/2 fractures with suture tape or metallic cerclage fixation concerning re-operation rates, union rates, loss of fixation and functional outcome measures. These results cannot be extrapolated to more complex injury patterns or surgical techniques in which prominence of implanted material is more likely. Level of evidence III.
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- 2022
16. Current Trends in Blood Flow Restriction
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Molly, Cuffe, Joel, Novak, Adnan, Saithna, H Scott, Strohmeyer, and Emily, Slaven
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Physiology ,Physiology (medical) - Abstract
Purpose: The purpose of the study was to explore how individuals in the United States of America applied BFR/KAATSU devices and administered BFR/KAATSU training. In addition, the study sought to examine safety topics related to BFR/KAATSU training.Methods: The study was completed using survey research. Subjects were recruited through Facebook, email, and word of mouth. The survey was developed, piloted, and finally deployed March 22, 2021-April 21, 2021.Results: In total, 148 consented to the research; 108 completed the survey, and of those 108, 70 indicated current use with BFR/KAATSU equipment. Professions represented included athletic training, personal training, physical therapy, and strength and conditioning. Among those currently using BFR/KAATSU training (n = 70), the following results were found. The most common devices used were inflatable devices (n = 43, 61.4%). Education completed prior to device administration was formal (n = 39, 55.7%) and/or self-directed (n = 37, 52.9%). Barriers were faced by 29 (41.4%) when trying to enact training. Techniques and parameters varied during application. Screening processes were used (n = 50, 71.4%) prior to training. The devices were used to determine restrictive pressure (n = 31, 44.3%), and a supine position was used most when determining initial restrictive pressure (n = 33, 47.1%). For subsequent restrictive pressure measurements, respondents repeated the same method used initially (n = 38, 54.3%). Workload was often defined as the length of time under tension/load (n = 22, 31.4%) and exercise was directly supervised (n = 52, 74.3%). Adverse effects included bruising, lightheadedness, and cramping (n = 15, 21.4%). The devices have also been applied on those with pathology (n = 16, 22.9%).Conclusion: Those using blood flow restriction/KAATSU devices came from several professions and used an assortment of devices for BFR/KAATSU training. Individuals applied devices using a variety of parameters on populations for which efficacy has and has not been well defined.
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- 2022
17. Suture Hook Versus All-Inside Repair for Longitudinal Tears of the Posterior Horn of the Medial Meniscus Concomitant to Anterior Cruciate Ligament Reconstruction: A Matched-Pair Analysis From the SANTI Study Group
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Lampros Gousopoulos, Graeme P. Hopper, Adnan Saithna, Charles Grob, Yoann Levy, Ibrahim Haidar, Jean-Marie Fayard, Mathieu Thaunat, Thais Dutra Vieira, and Bertrand Sonnery-Cottet
- Subjects
Cohort Studies ,Anterior Cruciate Ligament Reconstruction ,Sutures ,Anterior Cruciate Ligament Injuries ,Matched-Pair Analysis ,Humans ,Physical Therapy, Sports Therapy and Rehabilitation ,Orthopedics and Sports Medicine ,Menisci, Tibial ,Tibial Meniscus Injuries - Abstract
Background: Secondary meniscectomy rates after repair of longitudinal tears of the posterior horn of the medial meniscus (PHMM) performed concomitantly with anterior cruciate ligament reconstruction (ACLR) are reported to be as high as 25% with an all inside repair technique. Posteromedial portal suture hook repair is an emerging technique; however, it is unknown whether it confers a significantly reduced secondary meniscectomy rate compared with the current gold standard. Purpose/Hypothesis: The primary objective of this study was to compare the secondary meniscectomy rates of suture hook repair and all inside repair for longitudinal tears of the PHMM performed concomitant to ACLR. The secondary outcome was to determine the risk factors associated with the failure of the repair. It was hypothesized that repair with an all inside device would be associated with higher secondary meniscectomy rates when compared with suture hook repair and that concomitant anterolateral ligament reconstruction (ALLR) would confer improved meniscal repair survivorship. Study Design: Cohort study; Level of evidence, 3. Methods: Patients with longitudinal tears of the PHMM who underwent meniscal repair during primary ACLR between January 2011 and December 2015 at our institution were eligible for the study. Patients undergoing suture hook repair were propensity matched in a 1:1 ratio to patients who underwent all inside repair. At the end of the study period, secondary meniscectomy rates were determined. Results: The study population comprised 237 matched pairs. The mean follow up was 97.7 ± 17.3 months. Patients who underwent an all inside repair had a >2-fold higher failure rate compared with patients who underwent suture hook repair through a posteromedial portal (31.2% vs 15.6%; P = .0003). Patients in the suture hook repair group undergoing additional ALLR demonstrated a >3-fold higher meniscal repair survival rate compared with all other subgroups ( P = .0014). This association was not seen in the all inside repair group. The only statistically significant risk factor for meniscal repair failure was the suture repair technique (hazard ratio, 2.133 [95% CI, 1.383-3.292]; P = .0008). Conclusion: Suture hook repair through a posteromedial portal is associated with a significantly lower secondary meniscectomy rate when compared with the all inside meniscal repair of longitudinal tears of the PHMM performed at the time of ACLR. Furthermore, patients in the suture hook repair group who underwent an additional ALLR had a significantly better meniscal repair survivorship compared with all other subgroups.
- Published
- 2022
18. Editorial Commentary: Nonanatomic Lateral Extra-Articular Procedures Performed at the Time of Anterior Cruciate Ligament Reconstruction Risk Overconstraint: Anatomic Anterolateral Ligament Reconstruction Does Not
- Author
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Adnan Saithna
- Subjects
Joint Instability ,Ligaments ,Anterior Cruciate Ligament Reconstruction ,Knee Joint ,Anterior Cruciate Ligament Injuries ,Cadaver ,Humans ,Orthopedics and Sports Medicine ,Range of Motion, Articular ,Biomechanical Phenomena - Abstract
Isolated anterior cruciate ligament reconstruction is associated with a risk of graft rupture that is more than 5-fold higher than that of combined anterior cruciate ligament-anterolateral ligament (ALL) reconstruction at a mean follow-up of greater than 100 months. However, biomechanical and clinical studies report that overconstraint is a concern with nonanatomic lateral-sided reconstruction. In fact, the normal biomechanics of the native ALL are anisometric. The ligament is tight in extension (providing rotational control) and slack in flexion (allowing physiological internal rotation). The ALL femoral attachment is proximal and posterior to the lateral epicondyle. The tibial tunnel or tunnels are located anterior to the fibular head and posterior to the Gerdy tubercle. An ALL graft must lie deep to the iliotibial band and superficial to the lateral collateral ligament. Fixation is performed in extension and neutral rotation. A single- or double-strand technique may be used. Surgeons performing lateral extra-articular procedures must understand the technical pitfalls that can lead to overconstraint and must seek to avoid them. Overconstraint can occur for a number of reasons, including the use of nonanatomic reconstruction and technical errors in tensioning, fixation angle, and tunnel positioning.
- Published
- 2022
19. Outside-In Drilling Allows Avoidance of Two-Stage Surgery in Revision Anterior Cruciate Ligament Reconstruction
- Author
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Etienne Cavaignac, Adnan Saithna, Thomas Fradin, Ibrahim Haidar, Thais Dutra Vieira, Bertrand Sonnery-Cottet, Cedric Ngbilo, Johnny Rayes, and Julien Billières
- Subjects
Orthopedic surgery ,Two stage surgery ,030222 orthopedics ,medicine.medical_specialty ,Anterior cruciate ligament reconstruction ,business.industry ,medicine.medical_treatment ,Technical note ,030229 sport sciences ,Surgery ,03 medical and health sciences ,0302 clinical medicine ,Technical Note ,Medicine ,Orthopedics and Sports Medicine ,business ,RD701-811 - Abstract
The presence of preoperative tunnel widening and/or malposition can pose technical challenges for revision anterior cruciate ligament reconstruction. This Technical Note describes the use of outside-in drilling to avoid the need for 2-stage reconstruction in the presence of tunnel widening or semi-anatomic tunnels., Technique Video Video 1 This video presents a reproducible one-stage technique for the revision of anterior cruciate ligament reconstruction. It highlights the use of outside-in drilling to avoid the need for 2-stage reconstruction in the presence of tunnel widening or semi-anatomic tunnels.
- Published
- 2021
20. Return to Sport Composite Test After Anterior Cruciate Ligament Reconstruction (K-STARTS): Factors Affecting Return to Sport Test Score in a Retrospective Analysis of 676 Patients
- Author
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Florent Franck, Grégory Vigne, Charles Pioger, Bertrand Sonnery-Cottet, Isabelle Rogowski, Mathieu Thaunat, Adnan Saithna, Thais Dutra Vieira, Jean-Marie Fayard, and Meven Le Guen
- Subjects
Adult ,Male ,Adolescent ,Anterior cruciate ligament reconstruction ,medicine.medical_treatment ,Anterior cruciate ligament ,Physical Therapy, Sports Therapy and Rehabilitation ,Return to sport ,Young Adult ,03 medical and health sciences ,Sex Factors ,0302 clinical medicine ,medicine ,Retrospective analysis ,Humans ,Orthopedics and Sports Medicine ,Retrospective Studies ,Orthodontics ,Psychological Tests ,030222 orthopedics ,Anterior Cruciate Ligament Reconstruction ,business.industry ,Anterior Cruciate Ligament Injuries ,Hamstring Tendons ,Age Factors ,030229 sport sciences ,Acl rehabilitation ,Middle Aged ,Current Research ,Return to Sport ,Test (assessment) ,Treatment Outcome ,medicine.anatomical_structure ,Case-Control Studies ,Test score ,Athletic Injuries ,Exercise Test ,Female ,business ,Bone-Patellar Tendon-Bone Grafts - Abstract
Background: Return to sport (RTS) to the preinjury level is the main purpose after anterior cruciate ligament (ACL) reconstruction but the factors affecting the RTS are not completely known. Knee Santy Athletic Return to Sport (K-STARTS) is a composite test designed to assess readiness for RTS after ACL reconstruction. Purpose: To determine the key factors that influence K-STARTS scores in a large cohort of patients after ACL reconstruction. Study Design: Case-control study. Level of Evidence: Level 3. Methods: A retrospective analysis of prospectively collected data was undertaken. All patients who underwent ACL reconstruction surgery between March 2016 and May 2017 and also had a K-STARTS assessment at 6 months postoperatively were included. To identify factors influencing the K-STARTS score, an analysis of variance was performed. Age, sex, sports level, delay between injury and surgery, concomitant lesions, graft type, additional lateral tenodesis procedure, and participation in the RTS program were analyzed to identify factors influencing the K-STARTS score. Results: A total of 676 patients were included in the study. The K-STARTS score was significantly higher in male patients than in female patients (13.9 vs 12.4; P < 0.001), in younger patients (those aged Conclusion: Completion of a specific RTS program, in addition to standard rehabilitation, was the most important factor influencing the K-STARTS composite functional and psychological RTS test score at 6 months after ACL reconstruction. Clinical Relevance: This study shows that the completion of a specific RTS program affects positively the RTS test score at 6 months after ACL reconstruction.
- Published
- 2021
21. Editorial Commentary: Human Dermal Allograft Is Preferable to Fascia Lata Autograft Based on Similar Outcomes Without Donor-Site Morbidity
- Author
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Adnan Saithna
- Subjects
medicine.medical_specialty ,Shoulder Joint ,business.industry ,Allografts ,Rotator Cuff Injuries ,Surgery ,medicine.anatomical_structure ,Fascia lata ,Fascia Lata ,medicine ,Humans ,Tears ,Orthopedics and Sports Medicine ,Shoulder joint ,Rotator cuff ,Morbidity ,Autografts ,business ,Graft Type - Abstract
Superior capsular reconstruction (SCR) is increasingly considered a "game-changer" for young patients with irreparable rotator cuff tears. Popular graft choices include fascia lata autograft (FLA) and human dermal allograft (HDA), with the latter strongly preferred in North America and Europe. Despite that, there seems to be a general perception that FLAs are associated with better healing rates due to better biology. However, critical analysis of the literature demonstrates abundant limitations that preclude strong conclusions about whether one graft type is optimal. Furthermore, recent studies have demonstrated that HDAs used for SCR have good healing potential and are also associated with generally good short-term clinical outcomes. A clinical pearl is that humeral sided repair failures are not uncommon, and double-row repair techniques should be thoughtfully considered. The main downside of FLAs is the associated donor site morbidity. Given the lack of proven advantage of FLAs, the impetus to move away from the current trend to use HDAs is low.
- Published
- 2021
22. Combined Reconstruction of the Medial Patellofemoral Ligament and Medial Quadriceps Tendon–Femoral Ligament
- Author
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Luiz Fernando Machado Soares, Rafael Baroni Carvalho, Eduardo Frois Temponi, Lúcio Honório de Carvalho Júnior, Adnan Saithna, and Matheus Braga Jacques Gonçalves
- Subjects
Orthopedic surgery ,musculoskeletal diseases ,030222 orthopedics ,medicine.medical_specialty ,business.industry ,Patellar Dislocations ,030229 sport sciences ,Recurrent dislocation ,Anatomy ,Medial patellofemoral ligament ,musculoskeletal system ,Surgery ,03 medical and health sciences ,0302 clinical medicine ,medicine.anatomical_structure ,Technical Note ,Ligament ,medicine ,Orthopedics and Sports Medicine ,Displacement (orthopedic surgery) ,Quadriceps tendon ,Full extension ,business ,RD701-811 - Abstract
Most patellar dislocations are associated with disruption of the proximal medial patellar restraints (PMPRs). The PMPRs comprise the medial patellofemoral ligament (MPFL) and medial quadriceps tendon-femoral ligament (MQTFL). Although isolated MPFL reconstruction is the most frequently performed procedure for the surgical management of recurrent dislocation, recent studies have shown that the MQTFL has a synergistic role with the MPFL in resisting lateral patellar displacement close to full extension. It has therefore been suggested that surgical techniques that gain the benefits of both proximal and distal PMPR biomechanical behavior may be best. This article describes an established technique for combined MPFL and MQTFL reconstruction using semitendinosus autograft.
- Published
- 2021
23. Wit, Wisdom, and Whitewater: A Journey With the 2021 AANA Traveling Fellows
- Author
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Lucas S. McDonald, Robert W. Westermann, Kostas J. Economopoulos, Brian F. Grogan, Benjamin R. Graves, Adnan Saithna, and Richard L. Angelo
- Subjects
Travel ,Alanine ,Humans ,Orthopedics and Sports Medicine ,Societies, Medical - Published
- 2022
24. Risk Factors for Grade 3 Pivot Shift in Knees With Acute Anterior Cruciate Ligament Injuries: A Comprehensive Evaluation of the Importance of Osseous and Soft Tissue Parameters From the SANTI Study Group
- Author
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Andrea Ferretti, Bertrand Sonnery-Cottet, Edoardo Gaj, Thais Dutra Vieira, Valerio Andreozzi, Alessandro Annibaldi, Alessandro Carrozzo, Adnan Saithna, and Edoardo Monaco
- Subjects
Adult ,Joint Instability ,Male ,Knee Joint ,Anterior cruciate ligament ,Pivot shift ,ACL ,ALS ,pivot shift ,tibial slope ,Physical Therapy, Sports Therapy and Rehabilitation ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Humans ,Medicine ,Orthopedics and Sports Medicine ,Prospective Studies ,Orthodontics ,030222 orthopedics ,business.industry ,Anterior Cruciate Ligament Injuries ,Soft tissue ,030229 sport sciences ,Cross-Sectional Studies ,medicine.anatomical_structure ,Female ,business - Abstract
Background:Preoperative grade 3 pivot shift has been reported to be associated with higher rates of anterior cruciate ligament (ACL) failure, persistent instability, and inferior patient-reported outcomes. The etiology of a high-grade pivot shift is multifactorial, and numerous factors have been suggested to be responsible. More attention has recently been focused on injury to the anterolateral structures (ALS) as a risk factor for a grade 3 pivot shift.Purpose:To determine risk factors for grade 3 pivot shift, including soft tissue and osseous parameters.Study Design:Cross-sectional study; Level of evidence, 3.Methods:A prospective evaluation was undertaken of 200 consecutive patients undergoing acute ACL reconstruction (within 10 days of injury). An open exploration of the lateral side of the injured knee was performed at the time of the index procedure. Details regarding patient and injury characteristics were recorded, as were details of soft tissue injuries, including meniscal tears, ALS lesions, medial collateral ligament tears, and chondral injuries. Osseous parameters (tibial slope and condylar ratios) were determined per established magnetic resonance imaging protocols. A multivariate logistic regression with penalized maximum likelihood was used to identify risk factors associated with International Knee Documentation Committee (IKDC) grade 3 pivot shift.Results:The mean ± SD age of the population was 28.3 ± 9.8 years; 67.5% of patients were male. Among patients, 35 (17.5%) had a high-grade pivot shift (IKDC grade 3), and 165 (82.5%) had a low-grade pivot shift (IKDC grades 1 and 2). Univariate and multivariate logistic regression analysis demonstrated that injury to the ALS was the only significant risk factor for grade 3 pivot shift (odds ratio, 13.49; 95% CI, 1.80-1725.53).Conclusion:This comprehensive evaluation of soft tissue and osseous factors has identified that injury to the ALS is the most important risk factor for grade 3 pivot shift in acute ACL-injured knees.
- Published
- 2020
25. Editorial Commentary: Let’s ALL Agree—Anterior Cruciate Ligament Reconstruction Outcomes Need to Be Improved and Extra-Articular Procedures Have an Essential Role
- Author
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Adnan Saithna and Bertrand Sonnery-Cottet
- Subjects
Anterolateral ligament ,medicine.medical_specialty ,Knee Joint ,Anterior cruciate ligament reconstruction ,medicine.medical_treatment ,Anterior cruciate ligament ,Tenodesis ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Humans ,Orthopedics and Sports Medicine ,Extra-Articular ,Clinical efficacy ,Adverse effect ,Rupture ,030222 orthopedics ,Anterior Cruciate Ligament Reconstruction ,biology ,Athletes ,business.industry ,Anterior Cruciate Ligament Injuries ,030229 sport sciences ,musculoskeletal system ,biology.organism_classification ,Surgery ,surgical procedures, operative ,medicine.anatomical_structure ,Acl graft ,business ,human activities - Abstract
We are united as an orthopaedic community in trying to improve the outcomes of anterior cruciate ligament (ACL) reconstruction. Graft rupture rates of 10% to 28% are reported in high-risk populations, reoperation for non-graft rupture-related indications are reported in 18% to 26%, and only 50% to 65% of recreational athletes return to their preinjury level of sports. Numerous groups across the world have published studies providing evidence demonstrating significant clinical efficacy of lateral extra-articular tenodesis in improving the outcomes of ACL surgery. Finally, the reductions in ACL graft rupture rates augmented with anterolateral ligament or a modified Lemaire reconstruction appear to be broadly comparable. In our hands, anterolateral ligament may result in fewer adverse events.
- Published
- 2020
26. Partial Medial Meniscectomy Using Needle Arthroscopy and a Standardized Local Anesthetic Protocol
- Author
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Adnan Saithna, Giorgio Bruni, Matthew Daggett, Andrea Redler, Johnathan Pettegrew, Edoardo Monaco, and Tyler Tucker
- Subjects
Orthopedic surgery ,Protocol (science) ,030222 orthopedics ,medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,Local anesthetic ,medicine.drug_class ,Sedation ,Arthroscopy ,030229 sport sciences ,Surgery ,03 medical and health sciences ,Standardized technique ,0302 clinical medicine ,Suture (anatomy) ,Technical Note ,medicine ,acl ,acl injury ,needle arthroscopic ,knee ,nanoscope ,Orthopedics and Sports Medicine ,Local anesthesia ,medicine.symptom ,business ,RD701-811 ,Arthroscopic partial medial meniscectomy - Abstract
Needle arthroscopic procedures of the knee offer potential advantages over standard arthroscopic procedures. The small size of the instruments allows for surgery without the use of a scalpel or suture, potentially decreased recovery times, and potentially reduced complication rates compared with traditional arthroscopy. In some patients, the procedure can be performed without the use of either general anesthesia or sedation. The purpose of this article is to provide a standardized technique guide for needle arthroscopic partial medial meniscectomy under local anesthesia.
- Published
- 2020
27. Non-invasive computer navigation can quantify the pivot shift maneuver with good to excellent reliability in healthy volunteers
- Author
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Alessandro Carrozzo, Adnan Saithna, Alessandro Annibaldi, Edoardo Monaco, Giorgio Bruni, Andrea Ferretti, Matthew Daggett, and Sara Lo Torto
- Subjects
medicine.medical_specialty ,Rotatory laxity ,Pivot shift ,Population ,Physical examination ,Inter- and intra-observer reliability ,03 medical and health sciences ,0302 clinical medicine ,Physical medicine and rehabilitation ,lcsh:Orthopedic surgery ,medicine ,Orthopedics and Sports Medicine ,Computer navigation ,Knee ,Navigation system ,education ,Reliability (statistics) ,030222 orthopedics ,education.field_of_study ,Ligaments ,medicine.diagnostic_test ,business.industry ,Research ,030229 sport sciences ,Pivot-shift test ,navigation system ,surface marker ,rotatory laxity ,pivot shift ,knee ,ligaments ,lcsh:RD701-811 ,Orthopedic surgery ,Surface marker ,business - Abstract
Purpose The aim of this study was to determine the inter- and intra-observer reliability of knee laxity assessment using a non-invasive navigation system in a population of healthy young athletes. It was hypothesized that knee laxity parameters recorded using non-invasive computer navigation would demonstrate good inter- and intra-observer reliability. Methods Healthy volunteers aged between 18 to 30 years were recruited to the study. Static and dynamic knee laxity parameters including anterior tibial translation and tibial rotation during the pivot shift test were recorded on awake patients using non-invasive computer navigation by two independent observers: at the first visit each athlete was evaluated by the consultant and resident surgeons independently; 6 weeks after the first visit all the participants were re-tested only by the resident surgeon. Inter- and intra-observer reliability was calculated and then interpreted according to Cicchetti’s criteria. Results One hundred healthy volunteers were recruited to the study, of these 38 were women (38%), and the average age was 25.5 ± 2.4 years. According to Cicchetti’s criteria the intra- and inter-observer reliability for static measurements were fair for anterior tibial translation (0.572 and 0.529, respectively) and excellent for total passive tibial rotation (0.859 and 0.883, respectively). For the dynamic measurements of translation and rotation during the pivot shift maneuver both measurements demonstrated good to excellent reliability with intra and inter observer reliability ranging from 0.684 to 0.936. Conclusion Non-invasive navigation for the assessment of knee laxity is associated with fair to excellent inter- and intra-observer reliability in a population of healthy volunteers.
- Published
- 2020
28. Clinical Outcomes of Arthroscopic Primary Anterior Cruciate Ligament Repair: A Systematic Review from the Scientific Anterior Cruciate Ligament Network International Study Group
- Author
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Bertrand Sonnery-Cottet, Hervé Ouanezar, Charles Pioger, Nikolaus Rosenstiel, Adnan Saithna, Florent Franck, Vikram Kandhari, Cesar Praz, and Thais Dutra Vieira
- Subjects
medicine.medical_specialty ,Time Factors ,Anterior cruciate ligament ,Population ,MEDLINE ,Physical examination ,law.invention ,Arthroscopy ,03 medical and health sciences ,0302 clinical medicine ,Randomized controlled trial ,law ,medicine ,Humans ,Orthopedics and Sports Medicine ,Anterior Cruciate Ligament ,education ,Rupture ,030222 orthopedics ,education.field_of_study ,Anterior Cruciate Ligament Reconstruction ,medicine.diagnostic_test ,business.industry ,Anterior Cruciate Ligament Injuries ,030229 sport sciences ,Evidence-based medicine ,Lysholm Knee Score ,Critical appraisal ,Treatment Outcome ,medicine.anatomical_structure ,Systematic review ,Physical therapy ,business - Abstract
Purpose To perform a systematic review of contemporary studies reporting clinical outcomes of primary anterior cruciate ligament (ACL) repair to determine whether these studies demonstrate any significant benefit of ACL repair and whether there is evidence of a deterioration of mid-term outcomes as seen in historical data. Methods A systematic review was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-analyses guidelines. A PubMed search using the keywords “repair” AND “Anterior Cruciate Ligament” was performed (limits: English language, publication date between January 1, 2014, and January 13, 2019). All identified studies reporting clinical outcomes of arthroscopic ACL repair were included. Critical appraisal was conducted using the Cochrane Risk of Bias Tool for Randomized Clinical Trials and the Methodological Index for Non-Randomized Studies. Basic parameters of each study including population characteristics, repair technique, physical examination findings, and clinical outcome scores were recorded and evaluated. Results Nineteen eligible studies were identified (including 5 comparative studies). None of the comparative studies showed any significant difference between repair and reconstruction groups with respect to International Knee Documentation Committee (IKDC), Lysholm, Tegner, side-to-side laxity difference, Lachman, pivot shift tests, or graft rupture rates. Four non-comparative studies reported outcomes at medium- to long-term follow up (range of mean follow up 43.3-79 months) with a mean Lysholm score between 85.3 and 100, mean IKDC subjective score between 87.3 and 100, and mean Tegner activity score between 5 and 7. Conclusions Comparative studies identified no significant differences between ACL repair and reconstruction with respect to Lysholm, IKDC, side-to-side laxity difference, pivot shift grade, or graft rupture rates. However, these studies had major limitations including small numbers and short durations of follow up. Case series demonstrated that excellent outcomes can be achieved at medium- to long-term follow up with the SAR technique. Level of Evidence IV; Systematic review of Level II to IV investigations.
- Published
- 2020
29. Ramp Lesions
- Author
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Raphael Serra Cruz, Bertrand Sonnery-Cottet, Adnan Saithna, Rodrigo A Goes, and Thais Dutra Vieira
- Subjects
High rate ,030222 orthopedics ,medicine.medical_specialty ,business.industry ,Biomechanics ,Physical Therapy, Sports Therapy and Rehabilitation ,Posteromedial corner ,030229 sport sciences ,Meniscus (anatomy) ,Meniscotibial ligament ,Surgery ,03 medical and health sciences ,0302 clinical medicine ,medicine.anatomical_structure ,Orthopedic surgery ,medicine ,Orthopedics and Sports Medicine ,Ramp lesion ,business ,human activities - Abstract
Meniscal ramp lesions occur much more frequently than was previously considered, and particularly so in ACL-injured knees. The historically high rate of missed diagnoses is a result of unfamiliarity with this injury pattern within the orthopedic community, and also the difficulty in diagnosis. A systematic exploration of the posteromedial compartment of the knee is mandatory to reliably identify ramp lesions. Failure to recognize and repair these injuries is associated with persistent anterior and posteromedial instability. Understanding their nature, biomechanics, and epidemiology is essential in allowing orthopedic surgeons to suspect their presence and adequately treat these lesions.
- Published
- 2020
30. Presoaking ACL grafts in vancomycin decreases the frequency of postoperative septic arthritis. A cohort study of 29,659 patients, systematic review, and meta-analysis from the SANTI Study Group
- Author
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Alessandro Carrozzo, Adnan Saithna, Alexandre Ferreira, Sylvain Guy, Lamine Chadli, Edoardo Monaco, Daniel Pérez-Prieto, Yoann Bohu, Thais Dutra Vieira, and Bertrand Sonnery-Cottet
- Subjects
ligaments ,acl ,anterior cruciate ligament reconstruction ,vancomycin ,knee ,Orthopedics and Sports Medicine ,septic arthritis - Abstract
Background: Presoaking anterior cruciate ligament (ACL) grafts in vancomycin has been reported to reduce the occurrence of septic arthritis (SA). However, strong recommendations for its universal use have been precluded by concerns regarding the fragility of previous meta-analyses. Purpose: The primary objective was to investigate whether presoaking ACL grafts in vancomycin was associated with a reduction in the rate of SA in a large series of patients. The secondary objective was to perform an updated systematic review and meta-analysis to determine the efficacy of vancomycin in reducing the rate of SA. Study Design: Cohort study and systematic review; Level of evidence, 3. Methods: A retrospective analysis of patients who underwent primary ACL reconstruction (ACLR) at our institution was undertaken. Rates of postoperative SA were determined and analyzed according to whether patients had received grafts presoaked in vancomycin. A systematic review of the literature and meta-analysis was performed. Odds ratios (ORs) for the risk of SA were calculated according to the inverse variance approach. Results were presented using forest plots, funnel plots, and the fragility index. Results: A total of 5300 patients underwent primary ACLR during the study period. The rate of SA was 0.34% (11/3228) in the control group and 0.05% (1/2072) in the presoaked group. There was a 5-fold greater risk of SA in patients who did not receive grafts presoaked in vancomycin (OR, 5.13 [95% CI, 1.16-48.30]; P = .04). Overall, 11 studies were included in the systematic review (29,659 ACLR procedures). The meta-analysis demonstrated a significantly greater risk of SA in those patients who did not receive grafts presoaked in vancomycin (OR, 14.39 [95% CI, 5.90-35.10]; fragility index = 23). This finding held true for the subpopulation receiving hamstring tendon grafts (fragility index = 16), but only a trend was demonstrated for bone–patellar tendon–bone grafts. Conclusion: The meta-analysis demonstrated that presoaking ACL grafts in vancomycin was associated with significant reductions in the rates of SA when all graft types were analyzed together. This finding held true specifically for hamstring tendon autografts. The fragility index of these findings allows for a strong recommendation for the universal use of vancomycin presoaking. However, it should be noted that only a trend toward reduced SA rates was demonstrated with presoaking bone–patellar tendon–bone autografts in vancomycin.
- Published
- 2022
31. Risk of graft rupture after adding a lateral extra-articular procedure at the time of acl reconstruction. A retrospective comparative study of elite alpine skiers from the french national team
- Author
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Sylvain Guy, Jean-Marie Fayard, Adnan Saithna, Sami Bahroun, Alexandre Ferreira, Alessandro Carrozzo, Stephane De Jesus, Stephane Bulle, Thais Dutra Vieira, and Bertrand Sonnery-Cottet
- Subjects
Knee Joint ,anterolateral ligament reconstruction ,Anterior Cruciate Ligament Injuries ,acl reconstruction ,Tenodesis ,lateral extra-articular procedures ,Physical Therapy, Sports Therapy and Rehabilitation ,acl reconstruction failure ,ski ,ski federation ,Cohort Studies ,Humans ,Orthopedics and Sports Medicine ,human activities ,Retrospective Studies - Abstract
Background: Elite alpine skiing is associated with a particularly high risk of anterior cruciate ligament (ACL) injuries, including graft ruptures. Despite a considerable focus on prevention, a reduction in injury rates has not been observed since the 1980s. Purpose: To determine whether elite alpine skiers undergoing ACL reconstruction (ACLR) with a lateral extra–articular procedure (LEAP) had a lower rate of ACL graft rupture when compared with those who underwent isolated ACLR. Study Design: Cohort study; Level of evidence, 3. Methods: Elite skiers from the French ski team who had undergone ACLR, with or without a LEAP, and had a minimum follow–up of 2 years were identified from the national ski team database. Rates of secondary ACL injury were determined via interrogation of the database, review of medical notes, and a final telemedicine interview. A multivariable analysis using the penalized Cox model was performed to explore the relationship among graft rupture, surgical procedure type, and any potential explanatory variables. Results: Among 81 ACLR procedures analyzed, 50 were isolated and 31 were combined with a LEAP, which was performed using modified Lemaire or anterolateral ligament reconstruction. Graft rupture rates were 34.0% in the isolated ACLR group and 6.5% in the ACLR + LEAP group. Multivariable analysis demonstrated that adding a LEAP was associated with a significant reduction in risk of ACL graft rupture when compared with isolated ACLR (hazard ratio [HR], 5.286 [95% CI, 1.068-26.149]; P = .0412). Age (HR, 1.114; P = .1157), sex (HR, 1.573; P = .3743), and ACL graft type (HR, 1.417; P = .5394) were not significant risk factors. Conclusion: Combined ACLR and LEAP were associated with a significant reduction in the rate of ACL graft rupture in elite alpine ski athletes. Those treated with isolated ACLR remain at extremely high risk of a second ACL injury.
- Published
- 2022
32. Anterolateral Ligament and the Anterolateral Corner
- Author
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Bertrand Sonnery-Cottet, Thais Dutra Vieira, Florent Franck, Jean Romain Delaloye, Adnan Saithna, and Charles Pioger
- Subjects
Anterolateral ligament ,surgical procedures, operative ,medicine.anatomical_structure ,business.industry ,Anterior cruciate ligament ,Internal rotation ,Biomechanics ,medicine ,Anatomy ,musculoskeletal system ,business ,human activities - Abstract
The anterolateral ligament (ALL) has an important role as a knee stabiliser of coupled anterior translation and internal rotation. Significant and clinically important advantages of combined anterior cruciate ligament (ACL) and ALL reconstruction compared with isolated ACL reconstruction have been demonstrated. This chapter provides an overview of the relevant anatomy and biomechanics, surgical technique and clinical outcomes of ALL reconstruction.
- Published
- 2022
33. List of Contributors
- Author
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Ferran Abat, Michelle E. Arakgi, Elizabeth A. Arendt, Erin C. Argentieri, Douglas W. Bartels, Charles A. Baumann, Alexander Beletsky, Sanjeev Bhatia, Tatum W. Braun, Charles H. Brown, Alissa J. Burge, Robert A. Burnett, Jourdan M. Cancienne, Jorge Chahla, Brian Chilelli, Melissa A. Christino, Brian J. Cole, Andrew J. Cosgarea, Eric J. Cotter, William M. Cregar, Iswadi Damasena, Robert S. Dean, David DeJour, Jean Romain Delaloye, Nicholas N. DePhillipo, Theresa Diermeier, Gregory S. DiFelice, Michael B. Ellman, Andrew K. Ence, Lars Engebretsen, Jack Farr, Florent Franck, Rachel M. Frank, Brett A. Fritsch, Freddie H. Fu, John P. Fulkerson, Nathan R. Graden, Andrew G. Geeslin, Pablo Eduardo Gelber, Alan Getgood, Ron Gilat, Matthew D. Giordanelli, Andreas Gomoll, Simon Görtz, Betina B. Hinckel, Hailey P. Huddleston, David H. Kahat, Patrick Kane, Nicholas I. Kennedy, Mininder S. Kocher, Kyle N. Kunze, Aaron J. Krych, Jaren LaGreca, Robert F. LaPrade, Christian Lattermann, George LeBus, Bruce A. Levy, Martin Lind, James P. Linklater, Alexander E. Loeb, Jeffrey A. Macalena, Bert Mandelbaum, R. Kyle Martin, Sean J. Meredith, Justin J. Mitchell, Gilbert Moatshe, Farrah A. Monibi, Brett Mueller, Volker Musahl, Stefano Muzzi, Luke T. O’Brien, Crystal A. Perkins, Charles Pioger, Hollis G. Potter, Nicolas Pujol, Sven E. Putnis, Martin Brett Raynor, Scott A. Rodeo, Adnan Saithna, Michael Scheidt, Henry D. Scholz, Breana Siljander, Harris S. Slone, Robert Smigielski, Bertrand Sonnery-Cottet, Tim Spalding, Marc Strauss, Suzanne M. Tabbaa, Adam J. Tagliero, Miho J. Tanaka, Tracy Tauro, Robert A. Teitge, Raúl Torres-Claramunt, Jelle P. van der List, Peter Verdonk, Harmen D. Vermeijden, Thais Dutra Vieira, Brady T. Williams, S. Clifton Willimon, Kelsey L. Wise, John W. Xerogeanes, Adam B. Yanke, and Kelly C. Zochowski
- Published
- 2022
34. The role of Superior Capsule Reconstruction in the irreparable rotator cuff tear — A systematic review
- Author
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Robert W. Jordan, Matthew Daggett, Adnan Saithna, and Nikhil Sharma
- Subjects
Reoperation ,medicine.medical_specialty ,MEDLINE ,Transplantation, Autologous ,Rotator Cuff Injuries ,03 medical and health sciences ,0302 clinical medicine ,Fascia lata ,Humans ,Transplantation, Homologous ,Medicine ,Orthopedic Procedures ,Orthopedics and Sports Medicine ,Rotator cuff ,030222 orthopedics ,Shoulder Joint ,business.industry ,Graft Survival ,Gold standard ,Capsule ,Recovery of Function ,030229 sport sciences ,Evidence-based medicine ,Surgery ,Treatment Outcome ,medicine.anatomical_structure ,Radiological weapon ,Tears ,Shoulder Injuries ,business ,Joint Capsule - Abstract
Background Irreparable rotator cuff tears in active patients provide a significant challenge and a consensus on the gold standard treatment is currently lacking. Superior capsule reconstruction (SCR) has recently been advocated and functions by providing a passive biological constraint to superior humeral head migration. The aim of this study is to systematically review the literature to evaluate the role of SCR in terms of functional outcome scores and failure rates. Patients and methods A review of the online databases Medline and EMBASE was conducted in accordance with the PRISMA guidelines on the 28th January 2019. Clinical studies reporting SCR using any type of graft or surgical technique were included if reporting either functional outcome scores or rate of secondary surgery. The studies were appraised using the Methodological index for non-randomised studies tool. Results The search strategy identified nine studies eligible for inclusion; five reported on fascia lata autografts and four studies reported on dermal allografts. All nine studies reported significant improvement in functional scores after SCR. Rates of secondary surgery were only provided in the dermal allograft studies at short-term follow-up (mean 10.9 to 32.4 months) and ranged from 0 to 18.6%. Radiological assessment revealed graft failure in 5.5 to 55% of dermal allografts and 4.2 to 36.1% of fascia lata autografts. Conclusion This review demonstrates that SCR is a useful treatment modality for patients with irreparable rotator cuff tears. SCR was associated with significantly improved functional outcome scores in all studies. All studies reported a preserved or increased mean AHD. The radiological graft failure rate ranged from 4.2 to 55% and the short duration of follow-up in most studies means that this remains an important concern that requires longer-term evaluation. Level of evidence IV, systematic review.
- Published
- 2019
35. Management of the failed first revision ACL reconstruction: Clinical outcomes of non-surgical management versus second revision ACL reconstruction
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Thomas Fradin, Adnan Saithna, Ibrahim M. Haidar, Johnny El Rayes, Abdo El Helou, Cédric Ngbilo, Charles Pioger, Thais Dutra Vieira, Graeme Hopper, and Bertrand Sonnery-Cottet
- Subjects
Orthopedics and Sports Medicine ,Surgery - Published
- 2022
36. Clinical outcomes following combined ACL and anterolateral ligament reconstruction versus isolated ACL reconstruction with bone-patellar tendon-bone autograft as a gold standard: A matched-pair analysis of 2018 patients
- Author
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Charles Pioger, Lampros Gousopoulos, Graeme Hopper, Thais Dutra Vieira, Joao Pedro Campos, Abdo El Helou, Corentin Philippe, and Adnan Saithna
- Subjects
Orthopedics and Sports Medicine ,Surgery - Published
- 2022
37. Significant Increase in the Rate of Meniscal and Chondral Injuries Between Primary and Revision Anterior Cruciate Ligament Reconstruction. (188)
- Author
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Adnan Saithna, Bertrand Sonnery-Cottet, Charles Pioger, Thomas Fradin, Johnny Rayes, Thais Dutra Vieira, Ibrahim Haidar, and Ngbilo Cédric
- Subjects
medicine.medical_specialty ,Anterior cruciate ligament reconstruction ,business.industry ,Anterior cruciate ligament ,medicine.medical_treatment ,musculoskeletal system ,Article ,Surgery ,medicine.anatomical_structure ,medicine ,Orthopedics and Sports Medicine ,business ,human activities ,Meniscal lesions - Abstract
Objectives: Anterior cruciate ligament (ACL) injuries are often associated with meniscal and chondral lesions. Meniscal lesions are present in up to 50% of ACL injured knees, and chondral lesions occur with an incidence of 20% to 40% in acute ACL-injured knees. The major importance of this lies in the fact that menisectomy and severe chondral damage are important predictors of poor outcomes including the subsequent development of knee osteoarthritis. Furthermore, patient reported outcomes following revision ACL reconstruction remain inferior to primary ACL reconstruction and this may, at least in part, be due to an increased incidence and severity of meniscal and chondral injuries. Although multiple studies have demonstrated that meniscal and chondral lesions are generally present at a higher rate at the time of revision ACL reconstruction when compared to primary ACL reconstruction, large studies following individual patients through primary and revision ACL reconstruction and tracking the change in the occurence of these injuries are scarce. The primary objective of this study was to determine the proportion of patients with meniscal and chondral injuries at the time of primary ACL reconstruction and determine how this rate changed by the time they underwent revision ACL reconstruction. The hypothesis was that the proportion of patients with meniscal and/or chondral lesions would be significantly greater at revision ACL reconstruction when compared to the primary procedures. Methods: Consecutive patients who underwent primary and then revision ACL reconstruction between March 1999 and February 2018 were identified using a single center registry. Patient characteristics, and intraoperative data from each procedure were collected and analyzed. This specifically included the occurrence and type of meniscal and chondral pathology. Descriptive statistics were used to evaluate the study sample using medians, descriptive data analysis was conducted depending on the nature of the criteria. Comparison between variables were assessed with student’s t test for quantitative variables and Mcnemar test for categorical variables. Statistical significance was set a t pResults: 213 consecutive patients underwent both primary ACL reconstruction and then revision surgery during the study period. The average time from primary ACLR to Revision was 46.8 ± 36.6 months (range 5-181).The mean age of patients at primary ACLR was 22.21±7.21 years. The mean age of patients at revision ACLR 26.1 ± 8.3 years. The mean IKDC for the entire population was 85.53 ± 11.59, The mean ACL-RSI score was 71.89 ± 23.95. The mean Lysholm score was 91.77±10.24. The proportion of patients with chondral lesions significantly increased from 7% at primary ACL to 15.5% at revision ACL (p < 0.05). Meniscal lesions also significantly increased from 44.6 % at primary ACLR to 70% at revision ACLR (p < 0.05). There was no significant difference in the rate of lateral meniscal lesions (11.7 vs 13.1, p > 0.05). However, the proportion of patients with a medial meniscus lesion (25.4 vs 36.2, p < 0.05) and bimeniscal lesions (7.5 vs 20.7, p < 0.05) increased significantly at revision ACL reconstruction. Conclusions: The proportion of patients with meniscal and//or chondral injuries at the time of revision ACL reconstruction is significantly higher than at the time of primary ACL reconstruction. Specifically, the rate of medial meniscus and bimeniscal injuries is significantly higher in patients undergoing revision ACL reconstruction
- Published
- 2021
38. Regarding 'Augmentation of Anterolateral Structures of the Knee Causes Undesirable Tibiofemoral Cartilage Contact in Double-Bundle Anterior Cruciate Ligament Reconstruction-A Randomized In-Vivo Biomechanics Study'
- Author
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From The Scientific Anterior Cruciate Ligament Network International Santi Study Group, Alessandro, Carrozzo, Adnan, Saithna, Graeme, Hopper, Charles, Grob, Yoann, Levy, Lampros, Gousopoulos, Etienne, Cavaignac, Thais Dutra, Vieira, and Bertrand, Sonnery-Cottet
- Subjects
Cartilage ,Anterior Cruciate Ligament Reconstruction ,Knee Joint ,Humans ,Biomechanical Phenomena - Published
- 2021
39. Arthroscopic Dissection of the Distal Semimembranosus Tendon: An Anatomical Perspective on Posteromedial Instability and Ramp Lesions
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Etienne Cavaignac, Charles Pioger, Adnan Saithna, Florent Frank, Thais Dutra Vieira, Bertrand Sonnery-Cottet, and Mathieu Thaunat
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Orthopedic surgery ,030222 orthopedics ,medicine.medical_specialty ,business.industry ,030229 sport sciences ,Semimembranosus tendon ,musculoskeletal system ,Instability ,Surgery ,03 medical and health sciences ,0302 clinical medicine ,medicine.anatomical_structure ,medicine ,Ligament ,Orthopedics and Sports Medicine ,Ramp lesion ,business ,Medial meniscus ,RD701-811 ,Knee instability - Abstract
Ramp lesions are increasingly recognized as a hallmark of posteromedial knee instability. Although the precise mechanisms through which these lesions occur is not completely understood, the distal semimembranosus complex has been implicated in their pathogenesis due to its attachment to the posterior horn of the medial meniscus (PHMM). Arthroscopic dissection of the distal semimembranosus tendon, and the application of traction to it, results in posterior translation of the PHMM and stretching of the meniscocapsular region. This demonstrates a mechanism through which ramp lesions can occur. Furthermore, the subsequent open dissection highlights the complex anatomical relationships of the distal semimembranosus tendon complex, particularly its tensioning effect on the posterior oblique ligament. The clinical relevance of this is that when a ramp lesion occurs, it is likely to be part of a spectrum of posteromedial injury and it should be considered a hallmark of posteromedial instability rather than an isolated meniscocapsular injury.
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- 2019
40. Professional Athletes Are at Higher Risk of Septic Arthritis After Anterior Cruciate Ligament Reconstruction: An Analysis of 4421 Consecutive Patients Including 265 Elite Athletes From the SANTI Study Group
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Felipe Galvão Abreu, Bertrand Sonnery-Cottet, Adnan Saithna, Matthew Daggett, Thais Dutra Vieira, Florent Franck, Guilherme Venturi de Abreu, and Charles Pioger
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Adult ,Male ,medicine.medical_specialty ,Adolescent ,Anterior cruciate ligament reconstruction ,medicine.medical_treatment ,Anterior cruciate ligament ,Population ,Physical Therapy, Sports Therapy and Rehabilitation ,Young Adult ,03 medical and health sciences ,Postoperative Complications ,0302 clinical medicine ,Risk Factors ,Odds Ratio ,Humans ,Medicine ,Orthopedics and Sports Medicine ,Elite athletes ,education ,Retrospective Studies ,Arthritis, Infectious ,030222 orthopedics ,education.field_of_study ,Anterior Cruciate Ligament Reconstruction ,biology ,business.industry ,Athletes ,Anterior Cruciate Ligament Injuries ,030229 sport sciences ,biology.organism_classification ,medicine.disease ,Pooled analysis ,medicine.anatomical_structure ,Case-Control Studies ,Athletic Injuries ,Physical therapy ,Female ,Septic arthritis ,business - Abstract
Background: Professional athletes are reported to be at greater risk of septic arthritis (SA) after anterior cruciate ligament reconstruction (ACLR) than the nonprofessional population. However, this finding has been controversial, and confusion has arisen in the literature owing to the underpowering of previous studies. Purpose/Hypothesis: The purpose was to report the differences in the rate of SA after ACLR in a large series of patients and to perform pooled data analysis including previously published studies. The hypothesis was that professional athletes have a significantly higher risk of SA than nonprofessional athletes. Study Design: Case-control study; Level of evidence, 3. Methods: A retrospective analysis of prospectively collected data was performed. Patients who underwent ACLR between January 2009 and July 2017 (with a minimum follow-up of 12 months) were considered for study eligibility. The rate of SA was determined, and multivariate analysis was used to evaluate potentially important risk factors, including participation in professional sport. Furthermore, a literature search was performed, and data were extracted from all identified relevant studies. A pooled data analysis was performed to determine differences in the risk of SA between professional and nonprofessional populations. Results: The current series comprised 4421 anterior cruciate ligament surgical procedures with 265 professional athletes. There were 15 cases of SA diagnosed over the study period (0.34%; 95% CI, 0.19%-0.56%). Ten cases occurred in professional athletes (3.8%; 95% CI, 1.82%-6.83%). The percentage of SA was 0.12% (95% CI, 0.04%-0.28%) in the nonprofessional population. Being a professional athlete was associated with a significantly increased risk of SA after ACLR (odds ratio, 21.038; 95% CI, 6.585-75.789; P < .0001). This finding was confirmed in the pooled data analysis comprising 11,416 patients including 1118 professional athletes (odds ratio, 5.03; 95% CI, 1.17-21.61). Conclusion: Professional athletes are at greater risk of SA after ACLR than nonprofessional athletes. The results of previous studies may have been conflicting owing to underpowering. The current study confirms the elevated risk by using a large clinical series and pooled data analysis to avoid the limitations of previous studies.
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- 2019
41. Is shortening of displaced midshaft clavicle fractures associated with inferior clinical outcomes following nonoperative management? A systematic review
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Adnan Saithna, Shahbaz S. Malik, Muaaz Tahir, Robert W. Jordan, and Sheraz S. Malik
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musculoskeletal diseases ,medicine.medical_specialty ,Nonunion ,MEDLINE ,law.invention ,Fractures, Bone ,03 medical and health sciences ,0302 clinical medicine ,Randomized controlled trial ,Fracture Fixation ,law ,Shoulder function ,Humans ,Medicine ,Orthopedics and Sports Medicine ,Nonoperative management ,Retrospective Studies ,030222 orthopedics ,business.industry ,030229 sport sciences ,General Medicine ,musculoskeletal system ,medicine.disease ,Clavicle ,Nonoperative treatment ,Surgery ,Radiography ,medicine.anatomical_structure ,Systematic review ,business - Abstract
Background Management of displaced midshaft clavicle fractures is controversial. Nonoperative treatment can lead to shortening, a risk factor for nonunion and poor functional outcomes. These inferior results have resulted in authors recommending surgical fixation for fractures with significant shortening. The aim of this systematic review was to analyze the effect of fracture shortening on shoulder function and nonunion rates in nonoperatively managed displaced midshaft clavicle fractures. Methods A review of the online databases MEDLINE and Embase was conducted on February 16, 2018, in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. The review was registered prospectively in the PROSPERO database. Clinical studies with midshaft clavicle fractures treated nonoperatively reporting an evaluation of the degree of clavicle shortening and either shoulder function or nonunion were included. The studies were appraised using the Methodological Index for Non-Randomized Studies (MINORS) tool. Results The search strategy identified 16 studies eligible for inclusion, comprising 4 randomized controlled trials and 12 nonrandomized retrospective comparative studies. Of the 12 case series, 11 failed to demonstrate any correlation between shortening and shoulder outcome scores. Of the 4 randomized controlled trials, 3 reported no significant association between fracture shortening and shoulder outcome scores. The studies also failed to demonstrate a significant association between nonunion and the presence of clavicle shortening. Conclusion There is no significant association between fracture shortening and nonunion rates or shoulder outcome scores in displaced midshaft clavicle fractures managed nonoperatively.
- Published
- 2019
42. Arthroscopic Repair of Proximal Posterior Cruciate Ligament Injuries in Pediatric Patients
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Gabriele Pisanu, Bertrand Sonnery-Cottet, Adnan Saithna, and João Luís Moura
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Orthopedic surgery ,Surgical repair ,030222 orthopedics ,medicine.medical_specialty ,education.field_of_study ,business.industry ,Population ,Technical note ,030229 sport sciences ,musculoskeletal system ,Surgical morbidity ,Surgery ,Avulsion ,03 medical and health sciences ,Fixation (surgical) ,0302 clinical medicine ,medicine.anatomical_structure ,Posterior cruciate ligament ,Technical Note ,medicine ,Ligament ,Orthopedics and Sports Medicine ,business ,education ,RD701-811 - Abstract
A renewed interest in arthroscopic knee ligament repair is emerging as a result of diagnostic and technical improvements. In pediatric patients with posterior cruciate ligament (PCL) injury, surgical reconstruction is rarely considered as an option because of the risk of iatrogenic physeal injury. In this Technical Note, we describe an arthroscopic surgical repair technique of PCL proximal avulsions in pediatric patients. The main reasons to consider arthroscopic PCL repair in this population include minimal surgical morbidity, preservation of the complex biomechanical properties of the native ligament, the small diameter of the bone tunnels, the physeal respecting nature of the procedure, the absence of graft harvesting, and the absence of fixation devices. The indications for this technique are limited to patients with an acute proximal PCL avulsion. Investigation performed from at Centre Orthopedique Santy, FIFA Medical Center of Excellence, Lyon, France.
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- 2019
43. Lateral extra-articular reconstruction length changes during weightbearing knee flexion and pivot shift: A simulation study
- Author
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Mathieu Thaunat, Jacques A. de Guise, Adnan Saithna, Yoann Blache, Biova Kouevidjin, Raphaël Dumas, Bertrand Sonnery-Cottet, Laboratoire Interuniversitaire de Biologie de la Motricité (LIBM ), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet [Saint-Étienne] (UJM)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry]), Group Ramsay-générale de santé, Centre orthopédique Santy , hôpital privé Jean-Mermoz, Laboratoire de recherche en imagerie et orthopédie [Montréal] (LIO), Ecole de Technologie Supérieure [Montréal] (ETS)-Centre Hospitalier de l'Université de Montréal (CHUM), Université de Montréal (UdeM)-Université de Montréal (UdeM), Laboratoire de Biomécanique et Mécanique des Chocs (LBMC UMR T9406), Université de Lyon-Université de Lyon-Institut Français des Sciences et Technologies des Transports, de l'Aménagement et des Réseaux (IFSTTAR), Southport and Ormskirk Hospitals, Centre orthopédique Santy, hôpital privé Jean-Mermoz, and this workwas performed within the framework of the LABEX PRIMES (ANR-11-LABX-0063) of Université de Lyon, within the 'Investissementsd'Avenir' program (ANR-11-IDEX-0007) operated by the FrenchNational Research Agency (ANR). The study was supported by the'Ramsay-Générale de Santé' group in Paris, France (COS-RGDS-2017-06-014-P-THAUNAT-M).
- Subjects
Adult ,Male ,musculoskeletal diseases ,Anterolateral ligament ,medicine.medical_specialty ,Knee Joint ,Anterior cruciate ligament ,Pivot shift ,Knee flexion ,Knee kinematics ,Weight-Bearing ,BIOMECANIQUE ,[SPI]Engineering Sciences [physics] ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Humans ,Computer Simulation ,Orthopedics and Sports Medicine ,Femur ,GENOU ,Range of Motion, Articular ,Physical Examination ,Orthodontics ,030222 orthopedics ,ANTEROLATERAL LIGAMENT ,Anterior Cruciate Ligament Reconstruction ,Tibia ,business.industry ,Biomechanics ,[SPI.MECA.BIOM]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Biomechanics [physics.med-ph] ,food and beverages ,030229 sport sciences ,COMPUTER MODELING ,musculoskeletal system ,Biomechanical Phenomena ,Surgery ,medicine.anatomical_structure ,Ligaments, Articular ,Squatting position ,KNEE ,business ,Epicondyle ,ANTERIOR CRUCIATE LIGAMENT - Abstract
Introduction Variations in the length of lateral extra-articular reconstruction (LER) have been widely investigated during knee flexion but there is no information about length changes during pivot shift. This study sought to assess the changes in LER tension during weightbearing knee flexion in a normal knee and in a computer-simulated pivot-shift scenario. Hypothesis Placing the femoral tunnel posterior and proximal to the lateral femoral epicondyle allows the LER to tighten early in the flexion range during weightbearing (squatting motion) and simulated pivot-shift. Material and methods A computer model was used to simulate weightbearing knee flexion and pivot shift scenarios. Changes in LER tension were calculated in both scenarios by estimating the distance between six femoral attachment sites (posterior and proximal to the lateral femoral epicondyle) and two tibial tunnel locations: Gerdy's tubercle (GT) and the anterolateral ligament (ALL) anatomic attachment site. Results Independent of the location of the femoral and tibial tunnels, the LER tightened by up to 22% of its resting length during the early portion of weightbearing knee flexion and then relaxed from 40° to 60° of knee flexion. The ALL tibial tunnel position allowed complete LER relaxation at 60° flexion whereas LER using the GT tibial tunnel position remained tighter. In the simulated pivot-shift test, and for all femoral tunnel locations, the LER tightened by 20% to 34% of its resting value for the GT tibial tunnel position and by 11% to 26% for the ALL tibial tunnel position. Discussion During weightbearing knee flexion, placing the femoral tunnel proximal and posterior to the femoral epicondyle was associated with LER tightening in the early degrees of flexion and LER relaxation between 40 and 60° flexion. LER tightening occurred during a simulated pivot-shift test supporting the concept that a posterior and proximal femoral LER tunnel position is most effective during weightbearing knee flexion and altered knee kinematics.
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- 2019
44. Correlation Between Magnetic Resonance Imaging and Surgical Exploration of the Anterolateral Structures of the Acute Anterior Cruciate Ligament–Injured Knee
- Author
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Adnan Saithna, Camilo Partezani Helito, Andrea Ferretti, Paulo Victor Partezani Helito, Edoardo Monaco, Angelo De Carli, Giuseppe Argento, and Andrea Redler
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Adult ,Male ,Anterolateral ligament ,Adolescent ,Knee Joint ,Anterior cruciate ligament ,Physical Therapy, Sports Therapy and Rehabilitation ,anterior cruciate ligament ,anterolateral ligament ,iliotibial band ,magnetic resonance imaging ,Cohort Studies ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Humans ,Orthopedics and Sports Medicine ,030222 orthopedics ,Anterior Cruciate Ligament Reconstruction ,medicine.diagnostic_test ,business.industry ,Anterior Cruciate Ligament Injuries ,Magnetic resonance imaging ,030229 sport sciences ,Anatomy ,Middle Aged ,medicine.anatomical_structure ,Female ,business - Abstract
Background: Combined anterior cruciate ligament (ACL) and anterolateral ligament (ALL) reconstruction is associated with improved clinical outcomes as compared with isolated intra-articular reconstruction, but the indications are not precisely defined. It may be the case that patients with proven anterolateral injury on preoperative imaging are most likely to benefit, but the accuracy of magnetic resonance imaging (MRI) is not known. Purpose/Hypothesis: To evaluate the correlation between MRI and surgical exploration in acute ACL-injured knees. The hypothesis was that a positive correlation would be identified between imaging and surgical findings for ALL/capsule and iliotibial band (ITB) injuries and that MRI would be highly sensitive, specific, and accurate. Study Design: Cohort study (diagnosis); Level of evidence, 2. Methods: Between January and May 2016, patients presenting with acute ACL injuries were considered for study eligibility. Included patients underwent 1.5-T MRI, which was evaluated by 3 investigators who attributed a Ferretti grade of injury to the anterolateral structures. At the time of ACL reconstruction, a lateral exploration was undertaken, and macroscopic injuries were identified. An evaluation of correlation between MRI and surgical exploration findings was performed. Results: Twenty-six patients participated in the study, and 96% had an ALL/capsule injury. The sensitivity, specificity, and accuracy of MRI and the correlation ( K) with surgical exploration findings were as follows, respectively: any ALL/capsule abnormality—88%, 100%, 88.5%, and 0.47; differentiating partial or complete ALL/capsule tears—78.6%, 41.7%, 61.5%, and 0.23; ITB injuries—62.5%, 40%, 50%, and 0.27. The percentage agreement between MRI and surgical findings was 88% for ALL/capsule injury, 65% for ITB injury, and 53% for Ferretti grading. Conclusion: Surgical exploration demonstrates that injuries occur to the anterolateral structures in almost all acute ACL-injured knees. MRI is highly sensitive, specific, and accurate for detection of abnormalities of the ALL/capsule and shows a high percentage of agreement with surgical findings. MRI has low sensitivity, specificity, and accuracy for the diagnosis of ITB injury. The Ferretti grade could not be reliably established from MRI, and there was only fair agreement between MRI and surgical findings with respect to ITB abnormalities and determination of whether ALL/capsular tears were partial or complete.
- Published
- 2019
45. Les résultats cliniques de la réparation du LCA ne sont pas inférieurs à ceux de la reconstruction : analyse appariée de 75 patients du SANTI Study Group
- Author
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Adnan Saithna, Alexandre Ferreira, Alessandro Carrozzo, Bertrand Sonnery-Cottet, Sylvain Guy, Thais Dutra Vieira, and Johannes Barth
- Subjects
medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,musculoskeletal, neural, and ocular physiology ,Gold standard ,Pivot shift ,Outcome measures ,Physical examination ,musculoskeletal system ,Surgery ,Return to sport ,surgical procedures, operative ,Early results ,Propensity score matching ,medicine ,Orthopedics and Sports Medicine ,business ,human activities ,Hamstring - Abstract
Introduction ACL reconstruction is the gold standard of surgical treatment for ACL tears. Recently, there has been a renewed interest in ACL repair, and early results are promising. The purpose of this study was to compare outcomes following ACL repair versus ACL reconstruction at a minimum follow-up of two years. Materiel et methode A retrospective analysis of prospectively collected data was undertaken. Patients who underwent ACL repair were matched 1 :1 to those who underwent ACL reconstruction using a propensity score. All patients underwent a return to sports evaluation (isokinetic test, K-START and ACL-RSI) at 6 months post-operatively. At final face-to-face follow-up, physical examination findings (including side to side laxity difference & pivot shift) were recorded. At final overall follow-up return to sport, complications, re-operations and outcome measures, including Lysholm, Tegner, International Knee Documentation Committee (IKDC), ACL-RSI, Forgotten Joint Score-12 (FJS) were recorded. Resultats Eighty-two patients with ACL repair were matched with 82 patients who underwent isolated ACL reconstruction. 7 matched pairs were lost to follow-up, leaving 75 patients in each group. At 6 months postoperatively, the ACL repair group had a lower mean hamstring muscle deficit (1.7 % ± 12.8) (p Conclusions The outcomes of ACL repair were non-inferior to ACL reconstruction with respect to IKDC subjective scores and anteroposterior laxity. ACL repair was associated with better forgotten joint score and superior hamstring strength, without increase in graft rupture rates. ACL repair can be considered a useful option in carefully selected patients.
- Published
- 2021
46. Arthrogenic Muscle Inhibition Following Knee Injury or Surgery: Pathophysiology, Classification, and Treatment
- Author
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Bertrand Sonnery-Cottet, Graeme P. Hopper, Lampros Gousopoulos, Thais Dutra Vieira, Mathieu Thaunat, Jean-Marie Fayard, Benjamin Freychet, Hervé Ouanezar, Etienne Cavaignac, and Adnan Saithna
- Abstract
Background: Arthrogenic muscle inhibition (AMI), a process in which quadriceps activation failure is caused by neural inhibition, is common following knee injury or surgery. No classifications exist to describe the variable presentations of AMI following knee injury. Indications: AMI can result in significant morbidity following knee injury, and it is essential to recognize and treat. It is crucial to identify patients at higher risk of postoperative complications as surgery should be delayed for specific rehabilitation programs. Understanding the pathophysiology of AMI is vital as this can guide therapeutic interventions. Technique Description: AMI following knee injury can present in a variety of ways including inhibition of the vastus medialis obliquus (VMO) muscle, extension deficits due to hamstring contracture, as well as chronic extension deficits. They also respond differently to conventional treatment modalities and often require longer and specific rehabilitation programs. Therefore, we propose a classification to define these different presentations. Results: Grade 0 is a normal VMO contraction. Grade 1a is when VMO contraction is inhibited but activation failure is reversible with simple exercises while Grade 1b requires longer and specific rehabilitation programs. Grade 2a is when VMO contraction is inhibited with an associated extension deficit due to hamstring contracture, but activation failure and loss of range of motion is reversible with simple exercises. However, Grade 2b is refractory to simple exercises, and longer and specific rehabilitation programs are required. Grade 3 is a chronic extension deficit that is irreducible without extensive posterior arthrolysis. Conclusion: In conclusion, AMI is a process in which quadriceps activation failure is caused by neural inhibition and is common following knee injury or surgery. Not taking AMI into account preoperatively can result in a very high risk of stiffness postoperatively. We propose a classification for AMI following knee injury or surgery, which describes different presentations and can be used to guide management.
- Published
- 2022
47. Rate of Tibial Tunnel Malposition Is Not Changed by Drilling Entirely Within the Stump of Preserved Remnants During ACL Reconstruction: A Prospective Comparative 3D-CT Study
- Author
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Tereza Lais Menegucci Zutin, Eduardo Federighi Baisi Chagas, Paulo Jose de Lorenzetti Gelas, Vitor Barion Castro de Padua, Adnan Saithna, Luis Fernando Patriarcha, Camilo Partezani Helito, and Lucas Fernandes Piazzalunga
- Subjects
medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,Tibial tunnel ,Anterior cruciate ligament ,Computed tomography ,computed tomography ,remnant preservation ,Article ,Surgery ,ACL reconstruction ,medicine.anatomical_structure ,surgical procedures, operative ,Remnant preservation ,medicine ,Orthopedics and Sports Medicine ,business ,anatomic ACL reconstruction ,ACL tunnel position - Abstract
Background: Remnant preservation during anterior cruciate ligament (ACL) reconstruction (ACLR) is controversial, and it is unclear whether the stump aids or obscures tibial tunnel positioning. Purpose/Hypothesis: The aim of this study was to determine whether the rate of tibial tunnel malposition is influenced by remnant preservation. The hypothesis was that using a remnant-preserving technique to drill entirely within the tibial stump would result in a significant reduction in tibial tunnel malposition as determined by postoperative 3-dimensional computed tomography (3D-CT). Study Design: Cohort study; Level of evidence, 2. Methods: Patients undergoing ACLR between October 2018 and December 2019 underwent surgery with a remnant-preserving technique (RP group) if they had a large stump present (>50% of the native ACL length) or if there was no remnant or if it was Results: Overall, 52 patients were included in the study (26 in each group). The mean tunnel positions were 36.8% ± 5.5% AP and 46.7% ± 2.9% ML in the RP group and 35.6% ± 4.8% AP and 47.3% ± 2.3% ML in the RA group. There were no significant differences in the mean AP ( P = .134) and ML ( P = .098) tunnel positions between the groups. Inter- and intraobserver reliability varied between fair to excellent and good to excellent, respectively. There was no significant difference in the rate of malposition between groups (RP group, 7.7%; RA group, 11.5%; P ≥ .999). Conclusion: Drilling entirely within the ACL tibial stump using a remnant-preserving reconstruction technique did not significantly change the rate of tunnel malposition when compared with stump ablation and utilization of standard landmarks.
- Published
- 2021
48. Indication d’une butée arthroscopique en cas de perte de substance glénoïdienne antérieure: revue systématique et résultats radiologiques
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Muaaz Tahir, Peter D'Alessandro, Shahbaz S. Malik, Adnan Saithna, Madara Kronberga, and Robert Jordan
- Subjects
High rate ,education.field_of_study ,medicine.medical_specialty ,business.industry ,Minimal clinically important difference ,Population ,Iliac crest ,Resorption ,Surgery ,Critical appraisal ,medicine.anatomical_structure ,Radiological weapon ,medicine ,Shoulder instability ,Orthopedics and Sports Medicine ,business ,education - Abstract
Introduction Recurrent shoulder instability is frequently associated with glenohumeral bone loss. Recently there has been a surge of interest in arthroscopically performed bone block procedures. The aim of this systematic review was to determine the clinical and radiological outcomes of arthroscopic glenoid bone block stabilisation for recurrent anterior dislocation. Methods This systematic review was performed in accordance with PRISMA guidelines. The search strategy was applied to MEDLINE and Embase databases on 20th July 2020. Studies reporting either clinical or radiological outcomes following arthroscopic bone block stabilisation for recurrent anterior dislocation were included. Primary outcomes were function and instability scores. Secondary outcomes included recurrent instability, graft union and resorption rates, return to activity/sports, and complications. Pooled analysis was performed when an outcome was uniformly reported by more than one study. Critical appraisal of studies was conducted using the Methodological Index for Non-Randomized Studies (MINORS) tool. Results Application of the search strategy resulted in the inclusion of 15 eligible studies; 12 used iliac crest bone graft while 3 used distal tibial allograft. The overall population comprised 265 patients (mean age range, 25.5–37.5 years; 79% of participants were men). All post-operative outcome scores were significantly improved, and the overall rate of recurrent instability was low (weighted mean 6.6%, range 0–18.2%) at mean follow up of 30.4 months. The Rowe score was the most frequently reported outcome measure, improving on average by 53.9 points at final follow-up, exceeding the minimal clinically important difference (MCID) threshold. Graft union rates ranged between 92–100% in 8 out of 10 studies at mean follow up range 6–78.7 months but two reported lower rates ranging from 58.3–84% for autografts and 37.5% for allografts. Graft resorption rates averaged between 10–16% for autografts and 32% for allografts. Hardware-related complications occurred in 2% with the most frequent being screw breakage or symptomatic mechanical irritation. Conclusion Arthroscopic bone block stabilisation is associated with high rates of graft union, significant improvements in the WOSI, Rowe, Constant and SSV scores (exceeding MCID thresholds where known), and a low rate of complications, including re-dislocation in the short to mid-term. Graft union rates were high, but the long-term implications of graft resorption (which occurs more frequently with allograft) are unknown. Longer follow-up of these patients and future experimental studies are required to further examine the effects of graft type and fixation methods. Level of Evidence IV; systematic review.
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- 2021
49. Regarding 'the effect of combined anterolateral and anterior cruciate ligament reconstruction on reducing pivot shift rate and clinical outcomes. A meta-analysis'
- Author
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Adnan Saithna, Bertrand Sonnery-Cottet, Camilo Partezani Helito, Jin Goo Kim, and Alessandro Carrozzo
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Orthodontics ,cruciate ligament ,reducing pivot ,meta analisys ,Anterior Cruciate Ligament Reconstruction ,Anterior cruciate ligament reconstruction ,business.industry ,Anterior Cruciate Ligament Injuries ,medicine.medical_treatment ,Pivot shift ,MEDLINE ,Text mining ,Meta-analysis ,Humans ,Medicine ,Orthopedics and Sports Medicine ,business - Published
- 2021
50. Management of adults with primary frozen shoulder in secondary care (UK FROST): a multicentre, pragmatic, three-arm, superiority randomised clinical trial
- Author
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Chris Peach Peach, Colin Senior, Lucksy Kottam, Kanthan Theivendran, Christopher Little, Charalambos Charalambous, Saleema Rex, Jamie Candal-Couto, Sally Spencer, Prabhakar Motkur, Matthew Northgraves, Catherine Hewitt, David J. Torgerson, A S C Bidwai, Joseph J. Dias, Sara Rodgers, Iain Macleod, R. Nanda, Harish Shanker, A. J. Brooksbank, Adam Ruman, Damian McClelland, Cormac Kelly, Iona Donnelly, Asim Butt, Jayanti Rai, Barnaby Sheridan, Douglas S. Robinson, Belen Corbacho, Emma Sharp, Philip Rosell, Sunil Garg, Francine Toye, Alison Armstrong, Lorna Goodchild, Cheryl Baldwick, Andrew Carr, Catriona McDaid, Ada Keding, Philip Ahrens, Simon H. L. Thomas, Ravi Ray, Amar Rangan, Richard Hawken, Tim Peckham, Balachandran Venateswaran, Gerry Richardson, Stephen Brealey, Neal Millar, Matthew Kent, Cushla Cooper, Cynthia Srikesavan, Nigel Hanchard, Adnan Saithna, Sarah E Lamb, Charalambos Panayiotou Charalambous, Mark Crowther, Steve Drew, Kapil Kumar, Jodi George Malal, Tim Matthews, and Tom Lawrence
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Adult ,Male ,medicine.medical_specialty ,030204 cardiovascular system & hematology ,Secondary Care ,Injections, Intra-Articular ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Randomized controlled trial ,Bursitis ,law ,Clinical endpoint ,Humans ,Medicine ,General anaesthesia ,030212 general & internal medicine ,Range of Motion, Articular ,Adverse effect ,Glucocorticoids ,Physical Therapy Modalities ,business.industry ,Frozen shoulder ,General Medicine ,Middle Aged ,A300 ,medicine.disease ,United Kingdom ,Joint Capsule Release ,Clinical trial ,Treatment Outcome ,Orthopedic surgery ,Physical therapy ,Manipulation, Orthopedic ,Female ,Range of motion ,business - Abstract
Manipulation under anaesthesia and arthroscopic capsular release are costly and invasive treatments for frozen shoulder, but their effectiveness remains uncertain. We compared these two surgical interventions with early structured physiotherapy plus steroid injection. In this multicentre, pragmatic, three-arm, superiority randomised trial, patients referred to secondary care for treatment of primary frozen shoulder were recruited from 35 hospital sites in the UK. Participants were adults (≥18 years) with unilateral frozen shoulder, characterised by restriction of passive external rotation (≥50%) in the affected shoulder. Participants were randomly assigned (2:2:1) to receive manipulation under anaesthesia, arthroscopic capsular release, or early structured physiotherapy. In manipulation under anaesthesia, the surgeon manipulated the affected shoulder to stretch and tear the tight capsule while the participant was under general anaesthesia, supplemented by a steroid injection. Arthroscopic capsular release, also done under general anaesthesia, involved surgically dividing the contracted anterior capsule in the rotator interval, followed by manipulation, with optional steroid injection. Both forms of surgery were followed by postprocedural physiotherapy. Early structured physiotherapy involved mobilisation techniques and a graduated home exercise programme supplemented by a steroid injection. Both early structured physiotherapy and postprocedural physiotherapy involved 12 sessions during up to 12 weeks. The primary outcome was the Oxford Shoulder Score (OSS; 0-48) at 12 months after randomisation, analysed by initial randomisation group. We sought a target difference of 5 OSS points between physiotherapy and either form of surgery, or 4 points between manipulation and capsular release. The trial registration is ISRCTN48804508. Between April 1, 2015, and Dec 31, 2017, we screened 914 patients, of whom 503 (55%) were randomly assigned. At 12 months, OSS data were available for 189 (94%) of 201 participants assigned to manipulation (mean estimate 38·3 points, 95% CI 36·9 to 39·7), 191 (94%) of 203 participants assigned to capsular release (40·3 points, 38·9 to 41·7), and 93 (94%) of 99 participants assigned to physiotherapy (37·2 points, 35·3 to 39·2). The mean group differences were 2·01 points (0·10 to 3·91) between the capsular release and manipulation groups, 3·06 points (0·71 to 5·41) between capsular release and physiotherapy, and 1·05 points (-1·28 to 3·39) between manipulation and physiotherapy. Eight serious adverse events were reported with capsular release and two with manipulation. At a willingness-to-pay threshold of £20 000 per quality-adjusted life-year, manipulation under anaesthesia had the highest probability of being cost-effective (0·8632, compared with 0·1366 for physiotherapy and 0·0002 for capsular release). All mean differences on the assessment of shoulder pain and function (OSS) at the primary endpoint of 12 months were less than the target differences. Therefore, none of the three interventions were clinically superior. Arthoscopic capsular release carried higher risks, and manipulation under anaesthesia was the most cost-effective. The National Institute for Health Research Health Technology Assessment programme. [Abstract copyright: Copyright © 2020 The Author(s). Publishedx by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license. Published by Elsevier Ltd.. All rights reserved.]
- Published
- 2020
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