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8,265 results on '"A. Viel"'

1. Payload-XL: A Platform for the In-Orbit Validation of the BRAVE FPGA

Author: Felipe Viel, Kleber R. Gouveia, Edilberto Costa, Márcio Oliveira, Miguel Boing, André Martins Pio de Mattos, Gabriel Mariano Marcelino, David Merodio Codinachs, Laio Oriel Seman, and Eduardo Augusto Bezerra
Subjects: General Computer Science, Control and Systems Engineering
Published: 2023
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2. Euclid preparation : XXIII. Derivation of galaxy physical properties with deep machine learning using mock fluxes and H-band images

Author: Collaboration, Euclid, Bisigello, L, Conselice, C J, Baes, M, Bolzonella, M, Brescia, M, Cavuoti, S, Cucciati, O, Humphrey, A, Hunt, L K, Maraston, C, Pozzetti, L, Tortora, C, van Mierlo, S E, Aghanim, N, Auricchio, N, Baldi, M, Bender, R, Bodendorf, C, Bonino, D, Branchini, E, Brinchmann, J, Camera, S, Capobianco, V, Carbone, C, Carretero, J, Castander, F J, Castellano, M, Cimatti, A, Congedo, G, Conversi, L, Copin, Y, Corcione, L, Courbin, F, Cropper, M, Da Silva, A, Degaudenzi, H, Douspis, M, Dubath, F, Duncan, C A J, Dupac, X, Dusini, S, Farrens, S, Ferriol, S, Frailis, M, Franceschi, E, Franzetti, P, Fumana, M, Garilli, B, Gillard, W, Gillis, B, Giocoli, C, Grazian, A, Grupp, F, Guzzo, L, Haugan, S V H, Holmes, W, Hormuth, F, Hornstrup, A, Jahnke, K, Kümmel, M, Kermiche, S, Kiessling, A, Kilbinger, M, Kohley, R, Kunz, M, Kurki-Suonio, H, Ligori, S, Lilje, P B, Lloro, I, Maiorano, E, Mansutti, O, Marggraf, O, Markovic, K, Marulli, F, Massey, R, Maurogordato, S, Medinaceli, E, Meneghetti, M, Merlin, E, Meylan, G, Moresco, M, Moscardini, L, Munari, E, Niemi, S M, Padilla, C, Paltani, S, Pasian, F, Pedersen, K, Pettorino, V, Polenta, G, Poncet, M, Popa, L, Raison, F, Renzi, A, Rhodes, J, Riccio, G, Rix, H -W, Romelli, E, Roncarelli, M, Rosset, C, Rossetti, E, Saglia, R, Sapone, D, Sartoris, B, Schneider, P, Scodeggio, M, Secroun, A, Seidel, G, Sirignano, C, Sirri, G, Stanco, L, Tallada-Crespí, P, Tavagnacco, D, Taylor, A N, Tereno, I, Toledo-Moreo, R, Torradeflot, F, Tutusaus, I, Valentijn, E A, Valenziano, L, Vassallo, T, Wang, Y, Zacchei, A, Zamorani, G, Zoubian, J, Andreon, S, Bardelli, S, Boucaud, A, Colodro-Conde, C, Ferdinando, D Di, Graciá-Carpio, J, Lindholm, V, Maino, D, Mei, S, Scottez, V, Sureau, F, Tenti, M, Zucca, E, Borlaff, A S, Ballardini, M, Biviano, A, Bozzo, E, Burigana, C, Cabanac, R, Cappi, A, Carvalho, C S, Casas, S, Castignani, G, Cooray, A, Coupon, J, Courtois, H M, Cuby, J, Davini, S, De Lucia, G, Desprez, G, Dole, H, Escartin, J A, Escoffier, S, Farina, M, Fotopoulou, S, Ganga, K, Garcia-Bellido, J, George, K, Giacomini, F, Gozaliasl, G, Hildebrandt, H, Hook, I, Huertas-Company, M, Kansal, V, Keihanen, E, Kirkpatrick, C C, Loureiro, A, Macías-Pérez, J F, Magliocchetti, M, Mainetti, G, Marcin, S, Martinelli, M, Martinet, N, Metcalf, R B, Monaco, P, Morgante, G, Nadathur, S, Nucita, A A, Patrizii, L, Peel, A, Potter, D, Pourtsidou, A, Pöntinen, M, Reimberg, P, Sánchez, A G, Sakr, Z, Schirmer, M, Sefusatti, E, Sereno, M, Stadel, J, Teyssier, R, Valieri, C, Valiviita, J, Viel, M, Astronomy, Euclid Collaboration, L. Bisigello, C. J. Conselice, M. Bae, M. Bolzonella, M. Brescia, S. Cavuoti, O. Cucciati, A. Humphrey, L. K. Hunt, C. Maraston, L. Pozzetti, C. Tortora, S. E. van Mierlo, N. Aghanim, N. Auricchio, M. Baldi, R. Bender, C. Bodendorf, D. Bonino, E. Branchini, J. Brinchmann, S. Camera, V. Capobianco, C. Carbone, J. Carretero, F. J. Castander, M. Castellano, A. Cimatti, G. Congedo, L. Conversi, Y. Copin, L. Corcione, F. Courbin, M. Cropper, A. Da Silva, H. Degaudenzi, M. Douspi, F. Dubath, C. A. J. Duncan, X. Dupac, S. Dusini, S. Farren, S. Ferriol, M. Fraili, E. Franceschi, P. Franzetti, M. Fumana, B. Garilli, W. Gillard, B. Gilli, C. Giocoli, A. Grazian, F. Grupp, L. Guzzo, S. V. H. Haugan, W. Holme, F. Hormuth, A. Hornstrup, K. Jahnke, M. Kümmel, S. Kermiche, A. Kiessling, M. Kilbinger, R. Kohley, M. Kunz, H. Kurki-Suonio, S. Ligori, P. B. Lilje, I. Lloro, E. Maiorano, O. Mansutti, O. Marggraf, K. Markovic, F. Marulli, R. Massey, S. Maurogordato, E. Medinaceli, M. Meneghetti, E. Merlin, G. Meylan, M. Moresco, L. Moscardini, E. Munari, S. M. Niemi, C. Padilla, S. Paltani, F. Pasian, K. Pedersen, V. Pettorino, G. Polenta, M. Poncet, L. Popa, F. Raison, A. Renzi, J. Rhode, G. Riccio, H. -W. Rix, E. Romelli, M. Roncarelli, C. Rosset, E. Rossetti, R. Saglia, D. Sapone, B. Sartori, P. Schneider, M. Scodeggio, A. Secroun, G. Seidel, C. Sirignano, G. Sirri, L. Stanco, P. Tallada-Crespí, D. Tavagnacco, A. N. Taylor, I. Tereno, R. Toledo-Moreo, F. Torradeflot, I. Tutusau, E. A. Valentijn, L. Valenziano, T. Vassallo, Y. Wang, A. Zacchei, G. Zamorani, J. Zoubian, S. Andreon, S. Bardelli A. Boucaud, C. Colodro-Conde, D. Di Ferdinando, J. Graciá-Carpio, V. Lindholm, D. Maino, S. Mei, V. Scottez, F. Sureau, M. Tenti, E. Zucca, A. S. Borlaff, M. Ballardini, A. Biviano, E. Bozzo, C. Burigana, R. Cabanac, A. Cappi, C. S. Carvalho, S. Casa, G. Castignani, A. Cooray, J. Coupon, H. M. Courtoi, J. Cuby, S. Davini, G. De Lucia, G. Desprez, H. Dole, J. A. Escartin, S. Escoffier, M. Farina, S. Fotopoulou, K. Ganga, J. Garcia-Bellido, K. George, F. Giacomini, G. Gozaliasl, H. Hildebrandt, I. Hook, M. Huertas-Company, V. Kansal, E. Keihanen, C. C. Kirkpatrick, A. Loureiro, J. F. Macías-Pérez, M. Magliocchetti, G. Mainetti, S. Marcin, M. Martinelli, N. Martinet, R. B. Metcalf, P. Monaco, G. Morgante, S. Nadathur, A. A. Nucita, L. Patrizii, A. Peel, D. Potter, A. Pourtsidou, M. Pöntinen, P. Reimberg, A. G. Sánchez, Z. Sakr, M. Schirmer, E. Sefusatti, M. Sereno, J. Stadel, R. Teyssier, C. Valieri, J. Valiviita, M. Viel, Bisigello, L., Conselice, C. J., Baes, M., Bolzonella, M., Brescia, M., Cavuoti, S., Cucciati, O., Humphrey, A., Hunt, L. K., Maraston11, C., Pozzetti, L., Tortora, C., van Mierlo, S. E., Aghanim, N., Auricchio, N., Baldi, M., Bender, R., Bodendorf, C., Bonino, D., Branchini, E., Brinchmann, J., Camera, S., Capobianco, V., Carbone, C., Carretero, J., Castander, F. J., Castellano, M., Cimatti, A., Congedo, G., Conversi, L., Copin, Y., Corcione, L., Courbin, F., Cropper, M., Da Silva, A., Degaudenzi, H., Douspis, M., Dubath, F., Duncan, C. A. J., Dupac, X., Dusini, S., Farrens, S., Ferriol, S., Frailis, M., Franceschi, E., Franzetti, P., Fumana, M., Garilli, B., Gillard, W., Gillis, B., Giocoli, C., Grazian, A., Grupp, F., Guzzo, L., Haugan, S. V. H., Holmes, W., Hormuth, F., Hornstrup, A., Jahnke, K., Kümmel, M., Kermiche, S., Kiessling, A., Kilbinger, M., Kohley, R., Kunz, M., Kurki-Suonio, H., Ligori, S., Lilje, P. B., Lloro, I., Maiorano, E., Mansutti, O., Marggraf, O., Markovic, K., Marulli, F., Massey, R., Maurogordato, S., Medinaceli, E., Meneghetti, M., Merlin, E., Meylan, G., Moresco, M., Moscardini, L., Munari, E., Niemi, S. M., Padilla, C., Paltani, S., Pasian, F., Pedersen, K., Pettorino, V., Polenta, G., Poncet, M., Popa, L., Raison, F., Renzi, A., Rhodes, J., Riccio, G., Rix, H. -W., Romelli, E., Roncarelli, M., Rosset, C., Rossetti, E., Saglia, R., Sapone, D., Sartoris, B., Schneider, P., Scodeggio, M., Secroun, A., Seidel, G., Sirignano, C., Sirri, G., Stanco, L., Tallada-Crespí, P., Tavagnacco, D., Taylor, A. N., Tereno, I., Toledo-Moreo, R., Torradeflot, F., Tutusaus, I., Valentijn, E. A., Valenziano, L., Vassallo, T., Wang, Y., Zacchei, A., Zamorani, G., Zoubian, J., Andreon, S., Boucaud, S. Bardelli A., Colodro-Conde, C., Di Ferdinando, D., Graciá-Carpio, J., Lindholm, V., Maino, D., Mei, S., Scottez, V., Sureau, F., Tenti, M., Zucca, E., Borlaff, A. S., Ballardini, M., Biviano, A., Bozzo, E., Burigana, C., Cabanac, R., Cappi, A., Carvalho, C. S., Casas, S., Castignani, G., Cooray, A., Coupon, J., Courtois, H. M., Cuby, J., Davini, S., De Lucia, G., Desprez, G., Dole, H., Escartin, J. A., Escoffier, S., Farina, M., Fotopoulou, S., Ganga, K., Garcia-Bellido, J., George, K., Giacomini, F., Gozaliasl, G., Hildebrandt, H., Hook, I., Huertas-Company, M., Kansal, V., Keihanen, E., Kirkpatrick, C. C., Loureiro, A., Macías-Pérez, J. F., Magliocchetti, M., Mainetti, G., Marcin, S., Martinelli, M., Martinet, N., Metcalf, R. B., Monaco, P., Morgante, G., Nadathur, S., Nucita, A. A., Patrizii, L., Peel, A., Potter, D., Pourtsidou, A., Pöntinen, M., Reimberg, P., Sánchez, A. G., Sakr, Z., Schirmer, M., Sefusatti, E., Sereno, M., Stadel, J., Teyssier, R., Valieri, C., Valiviita111, J., Viel, M., Institut de Physique des 2 Infinis de Lyon (IP2I Lyon), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Astrophysique Interprétation Modélisation (AIM (UMR_7158 / UMR_E_9005 / UM_112)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Observatoire de la Côte d'Azur (OCA), Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Centre National d'Études Spatiales [Toulouse] (CNES), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Institut d'Astrophysique de Paris (IAP), Institut national des sciences de l'Univers (INSU - CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Institut de recherche en astrophysique et planétologie (IRAP), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Astrophysique de Marseille (LAM), Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Etude du Rayonnement et de la Matière en Astrophysique (LERMA), École normale supérieure - Paris (ENS-PSL), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université de Cergy Pontoise (UCP), Université Paris-Seine-Université Paris-Seine-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Subatomique et de Cosmologie (LPSC), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA)-Institut polytechnique de Grenoble - Grenoble Institute of Technology (Grenoble INP ), Université Grenoble Alpes (UGA), Centre de Calcul de l'IN2P3 (CC-IN2P3), and Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)
Subjects: FOS: Physical sciences, Euclid, Astronomy and Astrophysics, Astrophysics::Cosmology and Extragalactic Astrophysics, galaxies: general, galaxies: general, galaxies: photometry, galaxies: star formation, galaxies: evolution, Astrophysics - Astrophysics of Galaxies, Cosmology, galaxies: photometry, Physics and Astronomy, [SDU]Sciences of the Universe [physics], Space and Planetary Science, Astrophysics of Galaxies (astro-ph.GA), galaxies: star formation, photometry [galaxies], star formation [galaxies], galaxies: evolution, Astrophysics::Galaxy Astrophysics, evolution [galaxies], general [galaxies]
Abstract: Next generation telescopes, like Euclid, Rubin/LSST, and Roman, will open new windows on the Universe, allowing us to infer physical properties for tens of millions of galaxies. Machine learning methods are increasingly becoming the most efficient tools to handle this enormous amount of data, because they are often faster and more accurate than traditional methods. We investigate how well redshifts, stellar masses, and star-formation rates (SFR) can be measured with deep learning algorithms for observed galaxies within data mimicking the Euclid and Rubin/LSST surveys. We find that Deep Learning Neural Networks and Convolutional Neutral Networks (CNN), which are dependent on the parameter space of the training sample, perform well in measuring the properties of these galaxies and have a better accuracy than methods based on spectral energy distribution fitting. CNNs allow the processing of multi-band magnitudes together with $H_{\scriptscriptstyle\rm E}$-band images. We find that the estimates of stellar masses improve with the use of an image, but those of redshift and SFR do not. Our best results are deriving i) the redshift within a normalised error of less than 0.15 for 99.9$\%$ of the galaxies with S/N>3 in the $H_{\scriptscriptstyle\rm E}$-band; ii) the stellar mass within a factor of two ($\sim0.3 \rm dex$) for 99.5$\%$ of the considered galaxies; iii) the SFR within a factor of two ($\sim0.3 \rm dex$) for $\sim$70$\%$ of the sample. We discuss the implications of our work for application to surveys as well as how measurements of these galaxy parameters can be improved with deep learning., accepted for publication in MNRAS, 21 pages, 22 figures, 6 tables
Published: 2023
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3. PBPK Model To Predict Marbofloxacin Distribution in Edible Tissues and Intestinal Exposure in Pigs

Author: Alexis Viel, Anis Nouichi, Mélanie Le Van Suu, Jean-Guy Rolland, Pascal Sanders, Michel Laurentie, Jacqueline Manceau, and Jérôme Henri
Subjects: General Chemistry, General Agricultural and Biological Sciences
Published: 2023
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4. Possible evidence for a large-scale enhancement in the Lyman-α forest power spectrum at redshiftz≥ 4

Author: Margherita Molaro, Vid Iršič, James S Bolton, Maggie Lieu, Laura C Keating, Ewald Puchwein, Martin G Haehnelt, and Matteo Viel
Subjects: quasars: absorption lines, Settore FIS/05 - Astronomia e Astrofisica, Space and Planetary Science, Astronomy and Astrophysics, intergalactic medium, large-scale structure of Universe, methods: numerical
Abstract: Inhomogeneous reionization enhances the 1D Ly α forest power spectrum on large scales at redshifts z ≥ 4. This is due to coherent fluctuations in the ionized hydrogen fraction that arise from large-scale variations in the post-reionization gas temperature, which fade as the gas cools. It is therefore possible to use these relic fluctuations to constrain inhomogeneous reionization with the power spectrum at wavenumbers $\log _{10}(k/{\rm km^{-1}\, s})\lesssim -1.5$. We use the Sherwood-Relics suite of hybrid radiation hydrodynamical simulations to perform a first analysis of new Ly α forest power spectrum measurements at 4.0 ≤ z ≤ 4.6. These data extend to wavenumbers $\log _{10}(k/{\rm km^{-1}\, s})\simeq -3$, with a relative uncertainty of 10–20 per cent in each wavenumber bin. Our analysis returns a 2.7σ preference for an enhancement in the Ly α forest power spectrum at large scales, in excess of that expected for a spatially uniform ultraviolet background. This large-scale enhancement could be a signature of inhomogeneous reionization, although the statistical precision of these data is not yet sufficient for obtaining a robust detection of the relic post-reionization fluctuations. We show that future power spectrum measurements with relative uncertainties of ≲ 2.5 per cent should provide unambiguous evidence for an enhancement in the power spectrum on large scales.
Published: 2023
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5. HLA-DR expression on monocytes and outcome of anti-CD19 CAR T-cell therapy for large B-cell lymphoma

Author: Estelle Bourbon, Pierre Sesques, Morgane Gossez, Jérémie Tordo, Emmanuelle Ferrant, Violaine Safar, Florent Wallet, Guillaume Aussedat, Alizée Maarek, Fadhela Bouafia, Lionel Karlin, Dana Ghergus, Camille Golfier, Hélène Lequeu, Anne Lazareth, Vérane Schwiertz, Sébastien Viel, Maryam Idlhaj, Hervé Ghesquières, Guillaume Monneret, Emmanuel Bachy, Fabienne Venet, Centre Hospitalier Lyon Sud [CHU - HCL] (CHLS), Hospices Civils de Lyon (HCL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon, Centre International de Recherche en Infectiologie (CIRI), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Hôpital Edouard Herriot [CHU - HCL], Laboratoire Interuniversitaire de Biologie de la Motricité (LIBM ), and Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])
Subjects: [SDV]Life Sciences [q-bio], Hematology
Abstract: Despite their unprecedented success in relapsed/refractory (R/R) large B-cell lymphoma (LBCL), anti-CD19 CAR T cells are associated with significant toxicity, and more than half of patients relapse. As monocytes emerged as key players in CAR therapy, we sought to evaluate the evolution of HLA-DR expression on monocytes (mHLA-DR) before and after commercial anti-CD19 CAR T-cell infusion in a large cohort (n = 103) of patients with R/R LBCL and its association with adverse events and treatment response. Cy-Flu-based lymphodepletion (LD) upregulated mHLA-DR in 79% of the cases, whereas in 2l% of cases (15 patients), the mHLA-DR level decreased after LD, and this decrease was associated with poorer outcome. Low mHLA-DR at day minus 7 (D−7) (
Published: 2023
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6. Le DSA (règlement européen sur les services numériques), une étape majeure dans la régulation des plateformes numériques

Author: Laure Durand-Viel
Published: 2023
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7. The European Physical Journal C

Author: Aaron, E., Agnes, P., Ahmad, I., Albergo, S., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Amaudruz, P., Atzori Corona, M., Ave, M., Avetisov, I. Ch., Azzolini, O., Back, H. O., Balmforth, Z., Barrado, A., Barrillon, P., Basco, A., Batignani, G., Bocci, V., Bonivento, W. M., Bottino, B., Boulay, M. G., Busto, J., Cadeddu, M., Caminata, A., Canci, N., Capra, A., Caprioli, S., Caravati, M., Cargioli, N., Carlini, M., Castello, P., Cavalcante, P., Cavuoti, S., Cebrian, S., Cela Ruiz, J. M., Chashin, S., Chepurnov, A., Chyhyrynets, E., Cifarelli, L., Cintas, D., Citterio, M., Cleveland, B., Cocco, V., Conde Vilda, E., Consiglio, L., Copello, S., Covone, G., Czubak, M., D’Aniello, M., D’Auria, S., Da Rocha Rolo, M. D., Davini, S., De Cecco, S., De Guido, G., De Gruttola, D., De Pasquale, S., De Rosa, G., Dellacasa, G., Derbin, A. V., Devoto, A., Di Capua, F., Di Noto, L., Di Stefano, P., Dolganov, G., Dordei, F., Ellingwood, E., Erjavec, T., Farenzena, S., Fernandez Diaz, M., Fiorillo, G., Franchini, P., Franco, D., Funicello, N., Gabriele, F., Gahan, D., Galbiati, C., Gallina, G., Gallus, G., Garbini, M., Garcia Abia, P., Gendotti, A., Ghiano, C., Giganti, C., Giovanetti, G. K., Goicoechea Casanueva, V., Gola, A., Grauso, G., Grilli di Cortona, G., Grobov, A., Gromov, M., Guan, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B. R., Hallin, A. L., Hamer, A., Haranczyk, M., Hessel, T., Hill, S., Horikawa, S., Hubaut, F., Hucker, J., Hugues, T., Ianni, An., Ippolito, V., Jillings, C., Jois, S., Kachru, P., Kemp, A. A., Kendziora, C. L., Kimura, M., Kochanek, I., Kondo, K., Korga, G., Koulosousas, S., Kubankin, A., Kuss, M., Kuźniak, M., La Commara, M., Lai, M., Lami, N., Le Guirriec, E., Leason, E., Leoni, A., Lidey, L., Lippi, F., Lissia, M., Luzzi, L., Lychagina, O., Maccioni, N., Macfadyen, O., Machulin, I. N., Manecki, S., Manthos, I., Mapelli, L., Margotti, A., Mari, S. M., Mariani, C., Maricic, J., Marini, A., Martínez, M., Martoff, C. J., Mascia, M., Masoni, A., Matteucci, G., Mavrokoridis, K., Maxia, C., Mcdonald, A. B., Messina, A., Milincic, R., Mitra, A., Moharana, A., Moioli, S., Monroe, J., Moretti, E., Morrocchi, M., Mróz, T., Muratova, V. N., Muscas, C., Musico, P., Nania, R., Nessi, M., Nikolopoulos, K., Nowak, J., Olchansky, K., Oleinik, A., Oleynikov, V., Organtini, P., Ortiz de Solórzano, A., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Paternoster, G., Pegoraro, P. A., Pelczar, K., Pellegrini, L. A., Pellegrino, C., Pesudo, V., Piacentini, S., Pietrofaccia, L., Pino, N., Pocar, A., Poehlmann, D. M., Pordes, S., Pralavorio, P., Price, D., Ragusa, F., Ramachers, Y., Razeti, M., Renshaw, A. L., Rescigno, M., Retiere, F., Rignanese, L. P., Ripoli, C., Rivetti, A., Roberts, A., Roberts, C., Rode, J., Rogers, G., Romero, L., Rossi, M., Rubbia, A., Sabia, M. A., Sabiu, G. M., Salomone, P., Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Savarese, C., Scapparone, E., Schillaci, G., Schukman, F., Scioli, G., Simeone, M., Skensved, P., Skorokhvatov, M. D., Smirnov, O., Smirnova, T., Smith, B., Spadoni, F., Spangenberg, M., Stefanizzi, R., Steri, A., Stornelli, V., Stracka, S., Stringer, M., Sulis, S., Sung, A., Suvorov, Y., Szelc, A. M., Tartaglia, R., Taylor, A., Taylor, J., Tedesco, S., Testera, G., Thieme, K., Thorpe, T. N., Tonazzo, A., Tricomi, A., Unzhakov, E. V., Vallivilayil John, T., Van Uffelen, M., Viant, T., Viel, S., Vogelaar, R. B., Vossebeld, J., Wada, M., Walczak, M. B., Wang, H., Wang, Y., Westerdale, S., Williams, L., Wingerter-Seez, I., Wojaczyński, R., Wojcik, Ma. M., Wright, T., Xie, Y., Yang, C., Zabihi, A., Zakhary, P., Zani, A., Zichichi, A., Zuzel, G., Zykova &amp, M. P., DarkSide-20k, Collaboration, Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), DarkSide-20k, Aaron, E., Agnes, P., Ahmad, I., Albergo, S., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Amaudruz, P., Atzori Corona, M., Ave, M., Avetisov, I. C., Azzolini, O., Back, H. O., Balmforth, Z., Barrado, A., Barrillon, P., Basco, A., Batignani, G., Bocci, V., Bonivento, W. M., Bottino, B., Boulay, M. G., Busto, J., Cadeddu, M., Caminata, A., Canci, N., Capra, A., Caprioli, S., Caravati, M., Cargioli, N., Carlini, M., Castello, P., Cavalcante, P., Cavuoti, S., Cebrian, S., Cela Ruiz, J. M., Chashin, S., Chepurnov, A., Chyhyrynets, E., Cifarelli, L., Cintas, D., Citterio, M., Cleveland, B., Cocco, V., Conde Vilda, E., Consiglio, L., Copello, S., Covone, G., Czubak, M., D'Aniello, M., D'Auria, S., Da Rocha Rolo, M. D., Davini, S., De Cecco, S., De Guido, G., De Gruttola, D., De Pasquale, S., De Rosa, G., Dellacasa, G., Derbin, A. V., Devoto, A., Di Capua, F., Di Noto, L., Di Stefano, P., Dolganov, G., Dordei, F., Ellingwood, E., Erjavec, T., Farenzena, S., Fernandez Diaz, M., Fiorillo, G., Franchini, P., Franco, D., Funicello, N., Gabriele, F., Gahan, D., Galbiati, C., Gallina, G., Gallus, G., Garbini, M., Garcia Abia, P., Gendotti, A., Ghiano, C., Giganti, C., Giovanetti, G. K., Goicoechea Casanueva, V., Gola, A., Grauso, G., Grilli di Cortona, G., Grobov, A., Gromov, M., Guan, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B. R., Hallin, A. L., Hamer, A., Haranczyk, M., Hessel, T., Hill, S., Horikawa, S., Hubaut, F., Hucker, J., Hugues, T., Ianni, A., Ippolito, V., Jillings, C., Jois, S., Kachru, P., Kemp, A. A., Kendziora, C. L., Kimura, M., Kochanek, I., Kondo, K., Korga, G., Koulosousas, S., Kubankin, A., Kuss, M., Kuzniak, M., La Commara, M., Lai, M., Lami, N., Le Guirriec, E., Leason, E., Leoni, A., Lidey, L., Lippi, F., Lissia, M., Luzzi, L., Lychagina, O., Maccioni, N., Macfadyen, O., Machulin, I. N., Manecki, S., Manthos, I., Mapelli, L., Margotti, A., Mari, S. M., Mariani, C., Maricic, J., Marini, A., Martinez, M., Martoff, C. J., Mascia, M., Masoni, A., Matteucci, G., Mavrokoridis, K., Maxia, C., Mcdonald, A. B., Messina, A., Milincic, R., Mitra, A., Moharana, A., Moioli, S., Monroe, J., Moretti, E., Morrocchi, M., Mroz, T., Muratova, V. N., Muscas, C., Musico, P., Nania, R., Nessi, M., Nikolopoulos, K., Nowak, J., Olchansky, K., Oleinik, A., Oleynikov, V., Organtini, P., de Solorzano, A. O., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Paternoster, G., Pegoraro, P. A., Pelczar, K., Pellegrini, L. A., Pellegrino, C., Pesudo, V., Piacentini, S., Pietrofaccia, L., Pino, N., Pocar, A., Poehlmann, D. M., Pordes, S., Pralavorio, P., Price, D., Ragusa, F., Ramachers, Y., Razeti, M., Renshaw, A. L., Rescigno, M., Retiere, F., Rignanese, L. P., Ripoli, C., Rivetti, A., Roberts, A., Roberts, C., Rode, J., Rogers, G., Romero, L., Rossi, M., Rubbia, A., Sabia, M. A., Sabiu, G. M., Salomone, P., Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Savarese, C., Scapparone, E., Schillaci, G., Schukman, F., Scioli, G., Simeone, M., Skensved, P., Skorokhvatov, M. D., Smirnov, O., Smirnova, T., Smith, B., Spadoni, F., Spangenberg, M., Stefanizzi, R., Steri, A., Stornelli, V., Stracka, S., Stringer, M., Sulis, S., Sung, A., Suvorov, Y., Szelc, A. M., Tartaglia, R., Taylor, A., Taylor, J., Tedesco, S., Testera, G., Thieme, K., Thorpe, T. N., Tonazzo, A., Tricomi, A., Unzhakov, E. V., Vallivilayil John, T., Van Uffelen, M., Viant, T., Viel, S., Vogelaar, R. B., Vossebeld, J., Wada, M., Walczak, M. B., Wang, H., Wang, Y., Westerdale, S., Williams, L., Wingerter-Seez, I., Wojaczynski, R., Wojcik, M. M., Wright, T., Xie, Y., Yang, C., Zabihi, A., Zakhary, P., Zani, A., Zichichi, A., Zuzel, G., and Zykova, M. P.
Subjects: Physics - Instrumentation and Detectors, WIMP, dark matter, DarkSide-20k, stability, buildings, programming, nitrogen, cryogenic distillation, Gran Sasso, astro-ph.IM, cryogenics, quality, Dark Matter, Argon, [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Astrophysics - Instrumentation and Methods for Astrophysics, experimental results
Abstract: The Aria cryogenic distillation plant, located in Sardinia, Italy, is a key component of the DarkSide-20k experimental program for WIMP dark matter searches at the INFN Laboratori Nazionali del Gran Sasso, Italy. Aria is designed to purify the argon, extracted from underground wells in Colorado, USA, and used as the DarkSide-20k target material, to detector-grade quality. In this paper, we report the first measurement of argon isotopic separation by distillation with the 26 m tall Aria prototype. We discuss the measurement of the operating parameters of the column and the observation of the simultaneous separation of the three stable argon isotopes: $${}^{36}\hbox {Ar}$$ 36 Ar , $${}^{38}\textrm{Ar}$$ 38 Ar , and $${}^{40}\textrm{Ar}$$ 40 Ar . We also provide a detailed comparison of the experimental results with commercial process simulation software. This measurement of isotopic separation of argon is a significant achievement for the project, building on the success of the initial demonstration of isotopic separation of nitrogen using the same equipment in 2019.
Published: 2023
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8. The CAMELS Project: Public Data Release

Author: Francisco Villaescusa-Navarro, Shy Genel, Daniel Anglés-Alcázar, Lucia A. Perez, Pablo Villanueva-Domingo, Digvijay Wadekar, Helen Shao, Faizan G. Mohammad, Sultan Hassan, Emily Moser, Erwin T. Lau, Luis Fernando Machado Poletti Valle, Andrina Nicola, Leander Thiele, Yongseok Jo, Oliver H. E. Philcox, Benjamin D. Oppenheimer, Megan Tillman, ChangHoon Hahn, Neerav Kaushal, Alice Pisani, Matthew Gebhardt, Ana Maria Delgado, Joyce Caliendo, Christina Kreisch, Kaze W. K. Wong, William R. Coulton, Michael Eickenberg, Gabriele Parimbelli, Yueying Ni, Ulrich P. Steinwandel, Valentina La Torre, Romeel Dave, Nicholas Battaglia, Daisuke Nagai, David N. Spergel, Lars Hernquist, Blakesley Burkhart, Desika Narayanan, Benjamin Wandelt, Rachel S. Somerville, Greg L. Bryan, Matteo Viel, Yin Li, Vid Irsic, Katarina Kraljic, Federico Marinacci, Mark Vogelsberger, Villaescusa-Navarro, F [0000-0002-4816-0455], Genel, S [0000-0002-3185-1540], Anglés-Alcázar, D [0000-0001-5769-4945], Perez, LA [0000-0002-8449-1956], Villanueva-Domingo, P [0000-0002-0936-4279], Wadekar, D [0000-0002-2544-7533], Shao, H [0000-0002-0152-6747], Mohammad, FG [0000-0001-9243-7434], Hassan, S [0000-0002-1050-7572], Moser, E [0000-0003-1593-1505], Lau, ET [0000-0001-8914-8885], Machado Poletti Valle, LF [0000-0002-1948-3562], Thiele, L [0000-0003-2911-9163], Jo, Y [0000-0003-3977-1761], Philcox, OHE [0000-0002-3033-9932], Oppenheimer, BD [0000-0002-3391-2116], Tillman, M [0000-0002-1185-4111], Hahn, CH [0000-0003-1197-0902], Kaushal, N [0000-0003-4786-2348], Pisani, A [0000-0002-6146-4437], Caliendo, J [0000-0001-9719-7177], Kreisch, C [0000-0002-5061-7805], Wong, KWK [0000-0001-8432-7788], Coulton, WR [0000-0002-1297-3673], Parimbelli, G [0000-0002-2539-2472], Steinwandel, UP [0000-0001-8867-5026], Dave, R [0000-0003-2842-9434], Nagai, D [0000-0002-6766-5942], Spergel, DN [0000-0002-5151-0006], Hernquist, L [0000-0001-6950-1629], Burkhart, B [0000-0001-5817-5944], Narayanan, D [0000-0002-7064-4309], Wandelt, B [0000-0002-5854-8269], Somerville, RS [0000-0002-6748-6821], Bryan, GL [0000-0003-2630-9228], Viel, M [0000-0002-2642-5707], Li, Y [0000-0002-0701-1410], Irsic, V [0000-0002-5445-461X], Kraljic, K [0000-0001-6180-0245], Marinacci, F [0000-0003-3816-7028], Vogelsberger, M [0000-0001-8593-7692], Apollo - University of Cambridge Repository, HEP, INSPIRE, Institut d'Astrophysique de Paris (IAP), Institut national des sciences de l'Univers (INSU - CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Astrophysique de Marseille (LAM), Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS), and CAMELS
Subjects: FOS: Computer and information sciences, Computer Science - Machine Learning, Cosmology and Nongalactic Astrophysics (astro-ph.CO), Computer Science - Artificial Intelligence, Hydrodynamical simulations, FOS: Physical sciences, Astrophysics::Cosmology and Extragalactic Astrophysics, [INFO] Computer Science [cs], Machine Learning (cs.LG), Astrostatistics, Settore FIS/05 - Astronomia e Astrofisica, Cosmology, Galaxy formation, [INFO]Computer Science [cs], [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Instrumentation and Methods for Astrophysics (astro-ph.IM), Astrophysics::Galaxy Astrophysics, Astronomy and Astrophysics, Astrophysics - Astrophysics of Galaxies, Artificial Intelligence (cs.AI), Space and Planetary Science, [PHYS.PHYS.PHYS-INS-DET] Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Astrophysics of Galaxies (astro-ph.GA), [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], Astrophysics - Instrumentation and Methods for Astrophysics, [PHYS.ASTR] Physics [physics]/Astrophysics [astro-ph], Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: The Cosmology and Astrophysics with Machine Learning Simulations (CAMELS) project was developed to combine cosmology with astrophysics through thousands of cosmological hydrodynamic simulations and machine learning. CAMELS contains 4233 cosmological simulations, 2049 N-body simulations, and 2184 state-of-the-art hydrodynamic simulations that sample a vast volume in parameter space. In this paper, we present the CAMELS public data release, describing the characteristics of the CAMELS simulations and a variety of data products generated from them, including halo, subhalo, galaxy, and void catalogs, power spectra, bispectra, Lyα spectra, probability distribution functions, halo radial profiles, and X-rays photon lists. We also release over 1000 catalogs that contain billions of galaxies from CAMELS-SAM: a large collection of N-body simulations that have been combined with the Santa Cruz semianalytic model. We release all the data, comprising more than 350 terabytes and containing 143,922 snapshots, millions of halos, galaxies, and summary statistics. We provide further technical details on how to access, download, read, and process the data at https://camels.readthedocs.io., The Astrophysical Journal. Supplement Series, 265 (2), ISSN:1538-4365, ISSN:0067-0049
Published: 2023
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9. The Sherwood–Relics simulations: overview and impact of patchy reionization and pressure smoothing on the intergalactic medium

Author: Ewald Puchwein, James S Bolton, Laura C Keating, Margherita Molaro, Prakash Gaikwad, Girish Kulkarni, Martin G Haehnelt, Vid Iršič, Tomáš Šoltinský, Matteo Viel, Dominique Aubert, George D Becker, Avery Meiksin, and HEP, INSPIRE
Subjects: Cosmology and Nongalactic Astrophysics (astro-ph.CO), Settore FIS/05 - Astronomia e Astrofisica, Space and Planetary Science, FOS: Physical sciences, Astronomy and Astrophysics, [PHYS.ASTR] Physics [physics]/Astrophysics [astro-ph], Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: We present the Sherwood-Relics simulations, a new suite of large cosmological hydrodynamical simulations aimed at modelling the intergalactic medium (IGM) during and after the cosmic reionization of hydrogen. The suite consists of over 200 simulations that cover a wide range of astrophysical and cosmological parameters. It also includes simulations that use a new lightweight hybrid scheme for treating radiative transfer effects. This scheme follows the spatial variations in the ionizing radiation field, as well as the associated fluctuations in IGM temperature and pressure smoothing. It is computationally much cheaper than full radiation hydrodynamics simulations and circumvents the difficult task of calibrating a galaxy formation model to observational constraints on cosmic reionization. Using this hybrid technique, we study the spatial fluctuations in IGM properties that are seeded by patchy cosmic reionization. We investigate the relevant physical processes and assess their impact on the z > 4 Lyman-alpha forest. Our main findings are: (i) Consistent with previous studies patchy reionization causes large scale temperature fluctuations that persist well after the end of reionization, (ii) these increase the Lyman-alpha forest flux power spectrum on large scales, and (iii) result in a spatially varying pressure smoothing that correlates well with the local reionization redshift. (iv) Structures evaporated or puffed up by photoheating cause notable features in the Lyman-alpha forest, such as flat-bottom or double-dip absorption profiles., Version accepted for publication in MNRAS, some discussions added, data added to Fig. 8. 24 pages, 15 figures. Images and movies may be viewed at https://www.nottingham.ac.uk/astronomy/sherwood-relics/
Published: 2022
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10. Presence and Depletion of Sulfadiazine, Trimethoprim, and Oxytetracycline into Feathers of Treated Broiler Chickens and Impact on Antibiotic-Resistant Bacteria

Author: Estelle Dréano, Charlotte Valentin, Jean-François Taillandier, Angélique Travel, Christophe Soumet, Arnaud Bridier, Dominique Hurtaud-Pessel, Michel Laurentie, Alexis Viel, and Sophie Mompelat
Subjects: General Chemistry, General Agricultural and Biological Sciences
Abstract: The valorization of poultry byproducts, like feathers (processed to feather meal), in animal feed could contribute to the presence of veterinary drugs, including antibiotics. An animal study was carried out to study the fate of sulfadiazine, trimethoprim, and oxytetracycline in feathers, plasma, and droppings of broiler chickens. Cage and floor housing, different from current farm practices, were studied. Samples were analyzed by liquid chromatography-tandem mass spectrometry (LC-MS/MS). A longer presence of antibiotics was observed in feathers compared to plasma, with sulfadiazine being present the most. The internal presence (via blood) and the external presence (via droppings) of antibiotics in/on feathers were shown. Analysis of
Published: 2022
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11. Currículo e Formação Matemática: disputas na Licenciatura em Matemática

Author: Laís Cristina Viel Gereti and Angela Marta Pereira das Dores Savioli
Subjects: General Medicine
Abstract: Este artigo apresenta parte de uma pesquisa de doutorado, e tem como objetivo discutir e problematizar o currículo e a formação matemática dos cursos de Licenciatura em Matemática. Para isso, busca-se a partir dos estudos das teorias de currículo (tradicionais, críticas e pós-críticas) e de formação de professores, por meio da perspectiva do Modelo dos Campos Semânticos, entender e problematizar a formação matemática, assim como a pertinência de algumas disciplinas matemáticas e das relações e disputas de poder envolvidas nos cursos de Licenciatura em Matemática. Por fim, aponta-se alguns modos para reestruturar os cursos e oportunizar formações adequadas aos professores de Matemática da Educação Básica, com base na diferenciação da Matemática do matemático e da Matemática do professor de Matemática.
Published: 2022
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12. Clinical, splicing and functional analysis to classify BRCA2 exon 3 variants

Author: Thomassen, M., Mesman, R.L.S., Hansen, T.V.O., Menendez, M., Rossing, M., Esteban-Sanchez, A., Tudini, E., Torngren, T., Parsons, M.T., Pedersen, I.S., Teo, S.H., Kruse, T.A., Moller, P., Borg, A., Jensen, U.B., Christensen, L.L., Singer, C.F., Muhr, D., Santamarina, M., Brandao, R., Andresen, B.S., Feng, B.J., Canson, D., Richardson, M.E., Karam, R., Pesaran, T., LaDuca, H., Conner, B.R., Abualkheir, N., Hoang, L., Calleja, F.M.G.R., Andrews, L., James, P.A., Bunyan, D., Hamblett, A., Radice, P., Goldgar, D.E., Walker, L.C., Engel, C., Claes, K.B.M., Machackova, E., Baralle, D., Viel, A., Wappenschmidt, B., Lazaro, C., Vega, A., Vreeswijk, M.P.G., Hoya, M. de la, Spurdle, A.B., ENIGMA Consortium, RS: GROW - R4 - Reproductive and Perinatal Medicine, and Klinische Genetica
Subjects: splicing, AMP classification, quantitation, ACMG/AMP classification, dPCR, ACMG, Medicine and Health Sciences, Genetics, Biology and Life Sciences, BRCA2, Genetics (clinical), functional analysis
Abstract: Skipping of BRCA2 exon 3 (∆E3) is a naturally occurring splice event, complicating clinical classification of variants that may alter ∆E3 expression. This study used multiple evidence types to assess pathogenicity of 85 variants in/near BRCA2 exon 3. Bioinformatically predicted spliceogenic variants underwent mRNA splicing analysis using minigenes and/or patient samples. ∆E3 was measured using quantitative analysis. A mouse embryonic stem cell (mESC) based assay was used to determine the impact of 18 variants on mRNA splicing and protein function. For each variant, population frequency, bioinformatic predictions, clinical data and existing mRNA splicing and functional results were collated. Variant class was assigned using a gene-specific adaptation of ACMG/AMP guidelines, following a recently proposed points-based system. mRNA and mESC analysis combined identified six variants with transcript and/or functional profiles interpreted as loss of function. Cryptic splice site use for acceptor site variants generated a transcript encoding a shorter protein that retains activity. Overall, 69/85 (81%) variants were classified using the point-based approach. Our analysis shows the value of applying gene-specific ACMG/AMP guidelines using a points-based approach and highlights the consideration of cryptic splice site usage to appropriately assign PVS1 code strength. This article is protected by copyright. All rights reserved.
Published: 2022
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13. Utilizing a Blended + Flipped Learning Approach in a Calculus for Life and Management Sciences Classroom

Author: Dan Spencer, Chris Willis, Yan Shen, Molly Fenn, and Shira Viel
Subjects: General Mathematics, Education
Published: 2022
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14. Quantitative PCR reveals the frequency and distribution of 3 indigenous yeast species across a range of specialty cheeses

Author: A. Lamarche, M-H. Lessard, C. Viel, S.L. Turgeon, D. St-Gelais, and S. Labrie
Subjects: Oxygen, Milk, Cheese, Genetics, Animals, Animal Science and Zoology, Polymerase Chain Reaction, Ecosystem, Phylogeny, Food Science
Abstract: Indigenous microorganisms are important components of the complex ecosystem of many dairy foods including cheeses, and they are potential contributors to the development of a specific cheese's sensory properties. Among these indigenous microorganisms are the yeasts Cyberlindnera jadinii, Pichia kudriavzevii, and Kazachstania servazzii, which were previously detected using traditional microbiological methods in both raw milk and some artisanal specialty cheeses produced in the province of Québec, Canada. However, their levels across different cheese varieties are unknown. A highly specific and sensitive real-time quantitative PCR assay was developed to quantitate these yeast species in a variety of specialty cheeses (bloomy-rind, washed-rind, and natural-rind cheeses from raw, thermized, and pasteurized milks). The specificity of the quantitative PCR assay was validated, and it showed no cross-amplification with 11 other fungal microorganisms usually found in bloomy-rind and washed-rind cheeses. Cyberlindnera jadinii and P. kudriavzevii were found in the majority of the cheeses analyzed (25 of 29 and 24 of 29 cheeses, respectively) in concentrations up to 10
Published: 2022
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15. Euclid preparation : XX. The Complete Calibration of the Color-Redshift Relation survey: LBT observations and data release

Author: Euclid Collaboration, Saglia, R., De Nicola, S., Fabricius, M., Guglielmo, V., Snigula, J., Zöller, R., Bender, R., Heidt, J., Masters, D., Stern, D., Paltani, S., Amara, A., Auricchio, N., Baldi, M., Bodendorf, C., Bonino, D., Branchini, E., Brescia, M., Brinchmann, J., Camera, S., Capobianco, V., Carbone, C., Carretero, J., Castellano, M., Cavuoti, S., Cledassou, R., Congedo, G., Conselice, C. J., Conversi, L., Copin, Y., Corcione, L., Courbin, F., Cropper, M., Da Silva, A., Degaudenzi, H., Douspis, M., Dubath, F., Duncan, C. A. J., Dupac, X., Dusini, S., Farrens, S., Frailis, M., Franceschi, E., Galeotta, S., Garilli, B., Gillard, W., Gillis, B., Giocoli, C., Grazian, A., Grupp, F., Haugan, S. V. H., Hoekstra, H., Holmes, W., Hormuth, F., Hornstrup, A., Jahnke, K., Kümmel, M., Kermiche, S., Kiessling, A., Kunz, M., Kurki-Suonio, H., Laureijs, R., Ligori, S., Lilje, P. B., Lloro, I., Maiorano, E., Marggraf, O., Markovic, K., Marulli, F., Massey, R., McCracken, H. J., Melchior, M., Meylan, G., Moresco, M., Moscardini, L., Munari, E., Niemi, S. M., Padilla, C., Pasian, F., Pedersen, K., Percival, W. J., Pettorino, V., Pires, S., Poncet, M., Popa, L., Pozzetti, L., Raison, F., Renzi, A., Rhodes, J., Riccio, G., Romelli, E., Rossetti, E., Sapone, D., Sartoris, B., Schneider, P., Secroun, A., Seidel, G., Sirignano, C., Sirri, G., Stanco, L., Tallada-Crespí, P., Tavagnacco, D., Taylor, A. N., Tereno, I., Toledo-Moreo, R., Torradeflot, F., Tutusaus, I., Valentijn, E. A., Valenziano, L., Vassallo, T., Wang, Y., Zacchei, A., Zamorani, G., Zoubian, J., Andreon, S., Bardelli, S., Graciá-Carpio, J., Maino, D., Mauri, N., Tramacere, A., Zucca, E., Ayllon, A. Alvarez, Aussel, H., Baccigalupi, C., Balaguera-Antolínez, A., Ballardini, M., Biviano, A., Bolzonella, M., Bozzo, E., Burigana, C., Cabanac, R., Cappi, A., Carvalho, C. S., Casas, S., Castignani, G., Cooray, A., Coupon, J., Courtois, H. M., Davini, S., Desprez, G., Dole, H., Escartin, J. A., Escoffier, S., Farina, M., Fotopoulou, S., Ganga, K., Garcia-Bellido, J., George, K., Giacomini, F., Gozaliasl, G., Hildebrandt, H., Hook, I., Ilbert, O., Kansal, V., Kashlinsky, A., Keihanen, E., Kirkpatrick, C. C., Loureiro, A., Macías-Pérez, J., Magliocchetti, M., Mainetti, G., Maoli, R., Martinelli, M., Martinet, N., Metcalf, R. B., Morgante, G., Nadathur, S., Nucita, A. A., Patrizii, L., Popa, V., Porciani, C., Potter, D., Pourtsidou, A., Reimberg, P., Sánchez, A. G., Sakr, Z., Schirmer, M., Sefusatti, E., Sereno, M., Stadel, J., Teyssier, R., Valieri, C., Valiviita, J., Veropalumbo, A., Viel, M., Department of Physics, Research Program in Systems Oncology, Helsinki Institute of Physics, Saglia, R., De Nicola, S., Fabricius, M., Guglielmo, V., Snigula, J., Z??ller, R., Bender, R., Heidt, J., Masters, D., Stern, D., Paltani, S., Amara, A., Auricchio, N., Baldi, M., Bodendorf, C., Bonino, D., Branchini, E., Brescia, M., Brinchmann, J., Camera, S., Capobianco, V., Carbone, C., Carretero, J., Castellano, M., Cavuoti, S., Cledassou, R., Congedo, G., Conselice, C. J., Conversi, L., Copin, Y., Corcione, L., Courbin, F., Cropper, M., Da Silva, A., Degaudenzi, H., Douspis, M., Dubath, F., Duncan, C. A. J., Dupac, X., Dusini, S., Farrens, S., Frailis, M., Franceschi, E., Galeotta, S., Garilli, B., Gillard, W., Gillis, B., Giocoli, C., Grazian, A., Grupp, F., Haugan, S. V. H., Hoekstra, H., Holmes, W., Hormuth, F., Hornstrup, A., Jahnke, K., K??mmel, M., Kermiche, S., Kiessling, A., Kunz, M., Kurki-Suonio, H., Laureijs, R., Ligori, S., Lilje, P. B., Lloro, I., Maiorano, E., Marggraf, O., Markovic, K., Marulli, F., Massey, R., Mccracken, H. J., Melchior, M., Meylan, G., Moresco, M., Moscardini, L., Munari, E., Niemi, S. M., Padilla, C., Pasian, F., Pedersen, K., Percival, W. J., Pettorino, V., Pires, S., Poncet, M., Popa, L., Pozzetti, L., Raison, F., Renzi, A., Rhodes, J., Riccio, G., Romelli, E., Rossetti, E., Sapone, D., Sartoris, B., Schneider, P., Secroun, A., Seidel, G., Sirignano, C., Sirri, G., Stanco, L., Tallada-Cresp??, P., Tavagnacco, D., Taylor, A. N., Tereno, I., Toledo-Moreo, R., Torradeflot, F., Tutusaus, I., Valentijn, E. A., Valenziano, L., Vassallo, T., Wang, Y., Zacchei, A., Zamorani, G., Zoubian, J., Andreon, S., Bardelli, S., Graci??-Carpio, J., Maino, D., Mauri, N., Tramacere, A., Zucca, E., Alvarez Ayllon, A., Aussel, H., Baccigalupi, C., Balaguera-Antol??nez, A., Ballardini, M., Biviano, A., Bolzonella, M., Bozzo, E., Burigana, C., Cabanac, R., Cappi, A., Carvalho, C. S., Casas, S., Castignani, G., Cooray, A., Coupon, J., Courtois, H. M., Davini, S., Desprez, G., Dole, H., Escartin, J. A., Escoffier, S., Farina, M., Fotopoulou, S., Ganga, K., Garcia-Bellido, J., George, K., Giacomini, F., Gozaliasl, G., Hildebrandt, H., Hook, I., Ilbert, O., Kansal, V., Kashlinsky, A., Keihanen, E., Kirkpatrick, C. C., Loureiro, A., Mac??as-P??rez, J., Magliocchetti, M., Mainetti, G., Maoli, R., Martinelli, M., Martinet, N., Metcalf, R. B., Morgante, G., Nadathur, S., Nucita, A. A., Patrizii, L., Popa, V., Porciani, C., Potter, D., Pourtsidou, A., Reimberg, P., S??nchez, A. G., Sakr, Z., Schirmer, M., Sefusatti, E., Sereno, M., Stadel, J., Teyssier, R., Valieri, C., Valiviita, J., Veropalumbo, A., Viel, M., Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Astrophysique de Marseille (LAM), Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS), Euclid, Intelligent Systems, Astronomy, R. Saglia, S. De Nicola, M. Fabriciu, V. Guglielmo, J. Snigula, R. Zöller, R. Bender, J. Heidt, D. Master, D. Stern, S. Paltani, A. Amara, N. Auricchio, M. Baldi, C. Bodendorf, D. Bonino, E. Branchini, M. Brescia, J. Brinchmann, S. Camera, V. Capobianco, C. Carbone, J. Carretero, M. Castellano, S. Cavuoti, R. Cledassou, G. Congedo, C. J. Conselice, L. Conversi, Y. Copin, L. Corcione, F. Courbin, M. Cropper, A. Da Silva, H. Degaudenzi, M. Douspi, F. Dubath, C. A. J. Duncan, X. Dupac, S. Dusini, S. Farren, M. Fraili, E. Franceschi, S. Galeotta, B. Garilli, W. Gillard, B. Gilli, C. Giocoli, A. Grazian, F. Grupp, S. V. H. Haugan, H. Hoekstra, W. Holme, F. Hormuth, A. Hornstrup, K. Jahnke, M. Kümmel, S. Kermiche, A. Kiessling, M. Kunz, H. Kurki-Suonio, R. Laureij, S. Ligori, P. B. Lilje, I. Lloro, E. Maiorano, O. Marggraf, K. Markovic, F. Marulli, R. Massey, H. J. McCracken, M. Melchior, G. Meylan, M. Moresco, L. Moscardini, E. Munari, S. M. Niemi, C. Padilla, F. Pasian, K. Pedersen, W. J. Percival, V. Pettorino, S. Pire, M. Poncet, L. Popa, L. Pozzetti, F. Raison, A. Renzi, J. Rhode, G. Riccio, E. Romelli, E. Rossetti, D. Sapone, B. Sartori, P. Schneider, A. Secroun, G. Seidel, C. Sirignano, G. Sirri, L. Stanco, P. Tallada-Crespí, D. Tavagnacco, A. N. Taylor, I. Tereno, R. Toledo-Moreo, F. Torradeflot, I. Tutusau, E. A. Valentijn, L. Valenziano, T. Vassallo, Y. Wang, A. Zacchei, G. Zamorani, J. Zoubian, S. Andreon, S. Bardelli, J. Graciá-Carpio, D. Maino, N. Mauri, A. Tramacere, E. Zucca, A. Alvarez Ayllon, H. Aussel, C. Baccigalupi, A. Balaguera-Antolínez, M. Ballardini, A. Biviano, M. Bolzonella, E. Bozzo, C. Burigana, R. Cabanac, A. Cappi, C. S. Carvalho, S. Casa, G. Castignani, A. Cooray, J. Coupon, H. M. Courtoi, S. Davini, G. Desprez, H. Dole, J. A. Escartin, S. Escoffier, M. Farina, S. Fotopoulou, K. Ganga, J. Garcia-Bellido, K. George, F. Giacomini, G. Gozaliasl, H. Hildebrandt, I. Hook, O. Ilbert, V. Kansal, A. Kashlinsky, E. Keihanen, C. C. Kirkpatrick, A. Loureiro, J. Macías-Pérez, M. Magliocchetti, G. Mainetti, R. Maoli, M. Martinelli, N. Martinet, R. B. Metcalf, G. Morgante, S. Nadathur, A. A. Nucita, L. Patrizii, V. Popa, C. Porciani, D. Potter, A. Pourtsidou, P. Reimberg, A. G. Sánchez, Z. Sakr, M. Schirmer, E. Sefusatti, M. Sereno, J. Stadel, R. Teyssier, C. Valieri, J. Valiviita, A. Veropalumbo, M. Viel, Zöller, R., Kümmel, M., Tallada-Crespí, P., Graciá-Carpio, J., Balaguera-Antolínez, A., Macías-Pérez, J., and Sánchez, A. G.
Subjects: Cosmology and Nongalactic Astrophysics (astro-ph.CO), catalogs, Galaxies: distances and redshifts, surveys, Astrophysics - cosmology and nongalactic astrophysics, Astrophysics::Instrumentation and Methods for Astrophysics, Euclid, FOS: Physical sciences, Galaxies - distances and redshifts, Astronomy and Astrophysics, cosmos, Astrophysics::Cosmology and Extragalactic Astrophysics, Surveys, 115 Astronomy, Space science, Cosmology, deep imaging survey, Space and Planetary Science, distances and redshifts, catalogs, surveys [galaxies], distances and redshifts [Galaxies], galaxies: distances and redshifts, Catalogs, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], Astrophysics::Galaxy Astrophysics
Abstract: The Complete Calibration of the Color-Redshift Relation survey (C3R2) is a spectroscopic programme designed to empirically calibrate the galaxy color-redshift relation to the Euclid depth (I_E=24.5), a key ingredient for the success of Stage IV dark energy projects based on weak lensing cosmology. A spectroscopic calibration sample as representative as possible of the galaxies in the Euclid weak lensing sample is being collected, selecting galaxies from a self-organizing map (SOM) representation of the galaxy color space. Here, we present the results of a near-infrared H- and K-bands spectroscopic campaign carried out using the LUCI instruments at the LBT. For a total of 251 galaxies, we present new highly-reliable redshifts in the 1.3, A&A language edited version
Published: 2022
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16. Euclid preparation:XXIV. Calibration of the halo mass function in Λ(ν)CDM cosmologies

Author: Euclid Collaboration, Castro, T., Fumagalli, A., Angulo, R. E., Bocquet, S., Borgani, S., Carbone, C., Dakin, J., Dolag, K., Giocoli, C., Monaco, P., Ragagnin, A., Saro, A., Sefusatti, E., Costanzi, M., Brun, A. M. C. Le, Corasaniti, P. -S., Amara, A., Amendola, L., Baldi, M., Bender, R., Bodendorf, C., Branchini, E., Brescia, M., Camera, S., Capobianco, V., Carretero, J., Castellano, M., Cavuoti, S., Cimatti, A., Cledassou, R., Congedo, G., Conversi, L., Copin, Y., Corcione, L., Courbin, F., Da Silva, A., Degaudenzi, H., Douspis, M., Dubath, F., Duncan, C. A. J., Dupac, X., Farrens, S., Ferriol, S., Fosalba, P., Frailis, M., Franceschi, E., Galeotta, S., Garilli, B., Gillis, B., Grazian, A., Grupp, F., Haugan, S. V. H., Hormuth, F., Hornstrup, A., Hudelot, P., Jahnke, K., Kermiche, S., Kitching, T., Kunz, M., Kurki-Suonio, H., Lilje, P. B., Lloro, I., Mansutti, O., Marggraf, O., Marulli, F., Meneghetti, M., Merlin, E., Meylan, G., Moresco, M., Moscardini, L., Munari, E., Niemi, S. M., Padilla, C., Paltani, S., Pasian, F., Pedersen, K., Pettorino, V., Pires, S., Polenta, G., Poncet, M., Popa, L., Pozzetti, L., Raison, F., Rebolo, R., Renzi, A., Rhodes, J., Riccio, G., Romelli, E., Saglia, R., Sapone, D., Sartoris, B., Schneider, P., Seidel, G., Sirri, G., Stanco, L., Crespí, P. Tallada, Taylor, A. N., Toledo-Moreo, R., Torradeflot, F., Tutusaus, I., Valentijn, E. A., Valenziano, L., Vassallo, T., Wang, Y., Weller, J., Zacchei, A., Zamorani, G., Andreon, S., Bardelli, S., Bozzo, E., Colodro-Conde, C., Di Ferdinando, D., Farina, M., Graciá-Carpio, J., Lindholm, V., Neissner, C., Scottez, V., Tenti, M., Zucca, E., Baccigalupi, C., Balaguera-Antolínez, A., Ballardini, M., Bernardeau, F., Biviano, A., Blanchard, A., Borlaff, A. S., Burigana, C., Cabanac, R., Cappi, A., Carvalho, C. S., Casas, S., Castignani, G., Cooray, A., Coupon, J., Courtois, H. M., Davini, S., De Lucia, G., Desprez, G., Dole, H., Escartin, J. A., Escoffier, S., Finelli, F., Ganga, K., Garcia-Bellido, J., George, K., Gozaliasl, G., Hildebrandt, H., Hook, I., Ilić, S., Kansal, V., Keihanen, E., Kirkpatrick, C. C., Loureiro, A., Macias-Perez, J., Magliocchetti, M., Maoli, R., Marcin, S., Martinelli, M., Martinet, N., Matthew, S., Maturi, M., Metcalf, R. B., Morgante, G., Nadathur, S., Nucita, A. A., Patrizii, L., Peel, A., Popa, V., Porciani, C., Potter, D., Pourtsidou, A., Pöntinen, M., Sánchez, A. G., Sakr, Z., Schirmer, M., Sereno, M., Mancini, A. Spurio, Teyssier, R., Valiviita, J., Veropalumbo, A., Viel, M., Euclid, Collaboration, Castro, T., Fumagalli, A., Angulo, R. E., Bocquet, S., Borgani, S., Carbone, C., Dakin, J., Dolag, K., Giocoli, C., Monaco, P., Ragagnin, A., Saro, A., Sefusatti, E., Costanzi, M., Le Brun, A. M. C., Corasaniti, P. -S., Amara, A., Amendola, L., Baldi, M., Bender, R., Bodendorf, C., Branchini, E., Brescia, M., Camera, S., Capobianco, V., Carretero, J., Castellano, M., Cavuoti, S., Cimatti, A., Cledassou, R., Congedo, G., Conversi, L., Copin, Y., Corcione, L., Courbin, F., Da Silva, A., Degaudenzi, H., Douspis, M., Dubath, F., Duncan, C. A. J., Dupac, X., Farrens, S., Ferriol, S., Fosalba, P., Frailis, M., Franceschi, E., Galeotta, S., Garilli, B., Gillis, B., Grazian, A., Grupp, F., Haugan, S. V. H., Hormuth, F., Hornstrup, A., Hudelot, P., Jahnke, K., Kermiche, S., Kitching, T., Kunz, M., Kurki-Suonio, H., Lilje, P. B., Lloro, I., Mansutti, O., Marggraf, O., Marulli, F., Meneghetti, M., Merlin, E., Meylan, G., Moresco, M., Moscardini, L., Munari, E., Niemi, S. M., Padilla, C., Paltani, S., Pasian, F., Pedersen, K., Pettorino, V., Pires, S., Polenta, G., Poncet, M., Popa, L., Pozzetti, L., Raison, F., Rebolo, R., Renzi, A., Rhodes, J., Riccio, G., Romelli, E., Saglia, R., Sapone, D., Sartoris, B., Schneider, P., Seidel, G., Sirri, G., Stanco, L., Tallada Crespí, P., Taylor, A. N., Toledo-Moreo, R., Torradeflot, F., Tutusaus, I., Valentijn, E. A., Valenziano, L., Vassallo, T., Wang, Y., Weller, J., Zacchei, A., Zamorani, G., Andreon, S., Bardelli, S., Bozzo, E., Colodro-Conde, C., Di Ferdinando, D., Farina, M., Graciá-Carpio, J., Lindholm, V., Neissner, C., Scottez, V., Tenti, M., Zucca, E., Baccigalupi, C., Balaguera-Antolínez, A., Ballardini, M., Bernardeau, F., Biviano, A., Blanchard, A., Borlaff, A. S., Burigana, C., Cabanac, R., Cappi, A., Carvalho, C. S., Casas, S., Castignani, G., Cooray, A., Coupon, J., Courtois, H. M., Davini, S., De Lucia, G., Desprez, G., Dole, H., Escartin, J. A., Escoffier, S., Finelli, F., Ganga, K., Garcia-Bellido, J., George, K., Gozaliasl, G., Hildebrandt, H., Hook, I., Ilić, S., Kansal, V., Keihanen, E., Kirkpatrick, C. C., Loureiro, A., Macias-Perez, J., Magliocchetti, M., Maoli, R., Marcin, S., Martinelli, M., Martinet, N., Matthew, S., Maturi, M., Metcalf, R. B., Morgante, G., Nadathur, S., Nucita, A. A., Patrizii, L., Peel, A., Popa, V., Porciani, C., Potter, D., Pourtsidou, A., Pöntinen, M., Sánchez, A. G., Sakr, Z., Schirmer, M., Sereno, M., Spurio Mancini, A., Teyssier, R., Valiviita, J., Veropalumbo, A., and Viel, M.
Subjects: Astrophysic, cosmology theory, Cosmology and Nongalactic Astrophysics (astro-ph.CO), Large-scale structure of Universe, galaxies clusters general, theory [Cosmology], FOS: Physical sciences, clusters: general [Galaxies], Cosmology and Nongalactic Astrophysics
Abstract: Euclid's photometric galaxy cluster survey has the potential to be a very competitive cosmological probe. The main cosmological probe with observations of clusters is their number count, within which the halo mass function (HMF) is a key theoretical quantity. We present a new calibration of the analytic HMF, at the level of accuracy and precision required for the uncertainty in this quantity to be subdominant with respect to other sources of uncertainty in recovering cosmological parameters from Euclid cluster counts. Our model is calibrated against a suite of N-body simulations using a Bayesian approach taking into account systematic errors arising from numerical effects in the simulation. First, we test the convergence of HMF predictions from different N-body codes, by using initial conditions generated with different orders of Lagrangian Perturbation theory, and adopting different simulation box sizes and mass resolution. Then, we quantify the effect of using different halo-finder algorithms, and how the resulting differences propagate to the cosmological constraints. In order to trace the violation of universality in the HMF, we also analyse simulations based on initial conditions characterised by scale-free power spectra with different spectral indexes, assuming both Einstein--de Sitter and standard $Λ$CDM expansion histories. Based on these results, we construct a fitting function for the HMF that we demonstrate to be sub-percent accurate in reproducing results from 9 different variants of the $Λ$CDM model including massive neutrinos cosmologies. The calibration systematic uncertainty is largely sub-dominant with respect to the expected precision of future mass-observation relations; with the only notable exception of the effect due to the halo finder, that could lead to biased cosmological inference., 25 pages, 21 figures, 5 tables, 3 appendixes; v2 matches published version
Published: 2023
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17. Hospitalizations for infections in primary Sjögren’s syndrome patients: a nationwide incidence study

Author: Radjiv Goulabchand, Alain Makinson, Jacques Morel, Philine Witkowski-Durand-Viel, Nicolas Nagot, Paul Loubet, Camille Roubille, Danièle Noel, David Morquin, Kim Henry, Thibault Mura, and Philippe Guilpain
Subjects: General Medicine
Published: 2022
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18. Fenología del hielo lacustre: una comparación entre imágenes TSX y Sentinel-1 usando análisis de datos de campo en una región marítima de la Antártida

Author: Jorge Antônio Viel, Carina Petsch, Luiz Felipe Velho, and Kátia Kellem Da Rosa
Subjects: General Medicine
Abstract: El monitoreo a lo largo del tiempo de la dinámica fenológica de congelamiento de las superficies de los lagos en áreas libres de hielo es relevante para comprender los impactos del calentamiento mundial y los eventos climáticos extremos en las regiones polares. Los objetivos de este trabajo son: (I) establecer valores de retrodispersión para los blancos agua superficial libre de hielo y recubierta por hielo en lagos –con el soporte de datos de campo– utilizando las imágenes TerraSar-X (TSX) y Sentinel 1A - EW (S-1), teniendo como estudio de caso la península Fildes, Antárctica Marítima; (II) evaluar la relación entre los datos de retrodispersión y los datos meteorológicos; (III) evaluar las potencialidades de TSX y de S-1para el mapeo de la fenología de los lagos. El procesamiento de las imágenes SAR fue realizado en el SNAP y los datos meteorológicos fueron obtenidos en la Base Eduardo Frei Montalva. Se obtuvo el umbral de retrodispersión de -32 dB a -21 dB para el agua libre de hielo en los lagos estudiados en la imagen TSX, y para la Sentinel-1 hubo una variación de -18 dB a -15 dB para el agua libre de hielo de los lagos. La imagen TSX es la más adecuada para el monitoreo de la fenología de los lagos por su resolución espacial, mientras la S-1 se limita a los lagos con más de 10.000 m2. Es necesario tener en cuenta las condiciones meteorológicas, especialmente el viento, las precipitaciones de nieve y los cambios de temperatura, que representan alteraciones significativas en los valores de retrodispersión. Se puede utilizar las recomendaciones metodológicas referentes al uso de las imágenes TSX y S-1 para el mapeo de la cobertura de hielo en los lagos y el monitoreo de los eventos de quiebra de hielo y de derretimiento de la superficie de lagos en ambientes glaciales y periglaciales.
Published: 2022
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19. Forensic applications of micro-computed tomography: a systematic review

Author: Giorgia Franchetti, Guido Viel, Paolo Fais, Giulia Fichera, Diego Cecchin, Giovanni Cecchetto, and Chiara Giraudo
Subjects: Radiology, Nuclear Medicine and imaging
Abstract: Purpose The aim of this systematic review was to provide a comprehensive overview of micro-CT current applications in forensic pathology, anthropology, odontology, and neonatology. Methods A bibliographic research on the electronic databases Pubmed and Scopus was conducted in the time frame 01/01/2001–31/12/2021 without any language restrictions and applying the following free-text search strategy: “(micro-computed tomography OR micro-CT) AND (forensic OR legal)”. The following inclusion criteria were used: (A) English language; (B) Application of micro-CT to biological and/or non-biological materials to address at least one forensic issue (e.g., age estimation, identification of post-mortem interval). The papers selected by three independent investigators have been then classified according to the investigated materials. Results The bibliographic search provided 651 records, duplicates excluded. After screening for title and/or abstracts, according to criteria A and B, 157 full-text papers were evaluated for eligibility. Ninety-three papers, mostly (64) published between 2017 and 2021, were included; considering that two papers investigated several materials, an overall amount of 99 classifiable items was counted when referring to the materials investigated. It emerged that bones and cartilages (54.55%), followed by teeth (13.13%), were the most frequently analyzed materials. Moreover, micro-CT allowed the collection of structural, qualitative and/or quantitative information also for soft tissues, fetuses, insects, and foreign materials. Conclusion Forensic applications of micro-CT progressively increased in the last 5 years with very promising results. According to this evidence, we might expect in the near future a shift of its use from research purposes to clinical forensic cases.
Published: 2022
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20. Self-Management of ROV Umbilical Using Sliding Buoys and Stop

Author: Christophe Viel
Subjects: Human-Computer Interaction, Control and Optimization, Artificial Intelligence, Control and Systems Engineering, Mechanical Engineering, Biomedical Engineering, Computer Vision and Pattern Recognition, Computer Science Applications
Published: 2022
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21. 5GMED Seamless Connectivity for Digital Trains

Author: Jad Nasreddine, Juan Agustí, Philippe Veyssiere, Paul Caranton, Nuria Trujillo, Pascal Deliège, Luca Petrucci, Nathan Sanchiz-Viel, Jean-Emmanuel Deschaud, Judit Bastida, José López Luqe, Francisco Vázquez-Gallego, and Manuel Alfageme Alonso
Subjects: IM-MNO collaboration, Satellite, Digital Train, FRMCS, Gigabit-Train, 5G SA, 70GHz, ACS-GW
Abstract: The communication services of future trains require hyperconnectivity between trains and track. Future Railway Mobile Communication System (FRMCS) reserved bands will not be able to cover all digital train requirements including passengers’ services. The 5GMED project adopts the idea where Infrastructure Managers (IMs) will collaborate with Railway Undertaking (RU) to facilitate the connectivity to Mobile Network Operator (MNO) communication services and vice versa (complemented with the use of satellite networks), with an architecture open to build new business models and relationships between stakeholders. This approach encompasses an adaptative Gigabit train-to-track connectivity solution able to fit Digital Train requirements. The 5GMED project will demonstrate these capabilities through four representative services deployed on a TGV of SNCF (French Train Operator) in a challenging scenario: a cross-border section of the Mediterranean corridor between Figueres (Spain) and Perpignan (France).
Published: 2023
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22. Mitochondrial remodeling and energy metabolism adaptations in colonic crypts during spontaneous epithelial repair after colitis induction in mice

Author: Lan, Annaïg, Guerbette, Thomas, Andriamihaja, Mireille, Magnin, Benjamin, Bordet, Martin, Ferron, Pierre-Jean, Burel, Agnès, Viel, Roselyne, Fromenty, Bernard, Corlu, Anne, Blachier, François, Bouguen, Guillaume, Physiologie de la Nutrition et du Comportement Alimentaire (PNCA (UMR 0914)), AgroParisTech-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Nutrition, Métabolismes et Cancer (NuMeCan), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Biosit : biologie, santé, innovation technologique (SFR UMS CNRS 3480 - INSERM 018), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), and CHU Pontchaillou [Rennes]
Subjects: Spontaneous epithelial repair, [SDV]Life Sciences [q-bio], Colon epithelium, Mitochondrial respiration and dynamics, Oxidative stress response, DSS-Induced colitis
Abstract: International audience; Mucosal healing has emerged as a therapeutic goal to achieve lasting clinical remission in ulcerative colitis. Intestinal repair in response to inflammation presumably requires higher energy supplies for the restoration of intestinal barrier and physiological functions. However, epithelial energy metabolism during intestinal mucosal healing has been little studied, whereas inflammation-induced alterations have been reported in the main energy production site, the mitochondria. The aim of the present work was to assess the involvement of mitochondrial activity and the events influencing their function during spontaneous epithelial repair after colitis induction in mouse colonic crypts. The results obtained show adaptations of colonocyte metabolism during colitis to ensure maximal ATP production for supporting energetic demand by both oxidative phosphorylation and glycolysis in a context of decreased mitochondrial biogenesis and through mitochondrial function restoration during colon epithelial repair. In parallel, colitis-induced mitochondrial ROS production in colonic epithelial cells was rapidly associated with transient expression of GSH-related enzymes. Mitochondrial respiration in colonic crypts was markedly increased during both inflammatory and recovery phases despite decreased expression of several mitochondrial respiratory chain complex subunits after colitis induction. Rapid induction of mitochondrial fusion was associated with mitochondrial function restoration. Finally, in contrast with the kinetics expression of genes involved in mitochondrial oxidative metabolism and in glycolysis, the expression of glutaminase was markedly reduced in the colonic crypts both during colitis and repair phases. Overall, our data suggest that the epithelial repair after colitis induction is characterized by a rapid and transient increased capacity for mitochondrial ATP production in a context of apparent restoration of mitochondrial biogenesis and metabolic reorientation of energy production. The potential implication of energy production adaptations within colonic crypts to sustain mucosal healing in a context of altered fuel supply is discussed.
Published: 2023
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23. Exploiting Solid-State Dynamic Nuclear Polarization NMR Spectroscopy to Establish the Spatial Distribution of Polymorphic Phases in a Solid Material

Author: Cousin, Samuel, Hughes, Colan, Ziarelli, Fabio, Viel, Stéphane, Mollica, Giulia, Harris, Kenneth, Pinon, Arthur, and Thureau, Pierre
Abstract: Matlab + COMSOL files for reproducing numerical simulations presented in the article. Raw data are also available in the uploaded files
Published: 2023
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24. Successful treatment of JAK1 associated inflammatory disease

Author: Fayand, Antoine, Hentgen, Véronique, Posseme, Céline, Lacout, Carole, Picard, Capucine, Moguelet, Philippe, Cescato, Margaux, Sbeih, Nabiha, Moreau, Thomas R.J., Zhu, Yixiang Yj., Charuel, Jean-Luc, Corneau, Aurélien, Deibener-Kaminsky, Joelle, Dupuy, Stéphanie, Fusaro, Mathieu, Hoareau, Benedicte, Hovnanian, Alain, Langlois, Vincent, Le Corre, Laurent, Maciel, Thiago, Miskinyte, Snaigune, Miyara, Makoto, Moulinet, Thomas, Perret, Magali, Schuhmacher, Marie Hélène, Rignault-Bricard, Rachel, Viel, Sébastien, Vinit, Angélique, Soria, Angèle, Duffy, Darragh, Launay, Jean-Marie, Callebert, Jacques, Herbeuval, Jean Philippe, Rodero, Mathieu P, Georgin-Lavialle, Sophie, CHU Tenon [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques (LCBPT - UMR 8601), Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Groupe de Pathologie Infectieuse Pédiatrique [Paris] (GPIP), Société Française de Pédiatrie (SFP), Centre Hospitalier de Versailles André Mignot (CHV), Immunologie Translationnelle - Translational Immunology lab, Institut Pasteur [Paris] (IP)-Université Paris Cité (UPCité), CHU Trousseau [APHP], Sorbonne Université (SU), CHU Necker - Enfants Malades [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Paris Cité (UPCité), Imagine - Institut des maladies génétiques (IHU) (Imagine - U1163), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), CHU Pitié-Salpêtrière [AP-HP], Cytométrie Pitié-Salpêtrière (PASS-CYPS), Unité Mixte de Service Production et Analyse de données en Sciences de la vie et en Santé (PASS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Ingénierie Moléculaire et Physiopathologie Articulaire (IMoPA), Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Biomedtech Facilities (UMS 2009 / US36), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Groupe Hospitalier du Havre Hôpital Jacques Monod (MONTIVILLIERS) (GHH), Centre d'Immunologie et des Maladies Infectieuses (CIMI), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon, Centre Hospitalier Lyon Sud [CHU - HCL] (CHLS), Hospices Civils de Lyon (HCL), Centre Hospitalier Emile Durkheim [Epinal] (CH Epinal / CHED), Marqueurs cardiovasculaires en situation de stress (MASCOT (UMR_S_942 / U942)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord, and Hôpital Lariboisière-Fernand-Widal [APHP]
Subjects: JAK 1, JAK inhibitors, atopic dermatitis, inborn errors of immunity, [SDV]Life Sciences [q-bio], allergy
Abstract: International audience; Background: Gain of function (GOF) variants of JAK1 drive a rare immune dysregulation syndrome associated with atopic dermatitis, allergy and eosinophilia.Objectives: To describe the clinical and immunological characteristics associated with a new GOF variant of JAK1 and report the therapeutic efficacy of JAK inhibition.Methods: We identified a family affected by JAK1 associated autoinflammatory disease and performed clinical assessment and immunological monitoring on 9 patients. JAK1 signalling was studied by flow and mass cytometry in patients' cells at basal state, or after immune stimulation. A molecular disease signature in the blood was studied at the transcriptomic level. Patients were treated with one of two JAK inhibitors; either baricitinib or upadacitinib. Clinical, cellular, and molecular response were evaluated over a 2-year period.Results: Affected individuals displayed a syndromic disease with prominent allergy including atopic dermatitis, ichthyosis, arthralgia, chronic diarrhoea, disseminated calcifying fibrous tumours and elevated whole blood histamine levels. A variant of JAK1 localized in the pseudokinase domain was identified in all 9 affected tested patients. Hyper-phosphorylation of STAT3 was found in 5 out of 6 patients tested. Treatment of patients' cells with baricitinib controlled most of the atypical hyper-phosphorylation of STAT3. Administration of baricitinib to patients led to rapid improvement of the disease in all adults and was associated with reduction of systemic inflammation.Conclusions: Patients with this new JAK1 GOF pathogenic variant displayed very high levels of blood histamine and showed a variable combination of atopy with articular and gastrointestinal manifestations as well as calcifying fibrous tumours. The disease, that appears to be linked to STAT3 hyper-activation, was well controlled under treatment by JAK inhibitors in adult patients.
Published: 2023
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25. Un nouvel ensemble funéraire exceptionnel en contexte Chamblandes : les sépultures néolithiques de Sion-Avenue de Tourbillon VS

Author: Deville, Anaïs, Giozza, Gabriele, Mariéthoz, François, van Willingen, Samuel, Affolter, Jehanne, Altorfer, Kurt, Ansermet, Stefan, Détraz-Méroz, Jacqueline, Reynaud Savioz, Nicole, and Viel, Laurine
Abstract: Résumé Le site de Sion-Avenue de Tourbillon a été découvert en bordure sud du cône alluvial de la Sionne, à la faveur de la construction d’un immeuble d’habitations et de commerces. Les vestiges mis au jour montrent que les lieux ont été fréquentés à plusieurs reprises entre le Néolithique et la période antique. Les restes les plus significatifs sont représentés par cinq sépultures en ciste, que les datations radiocarbone situent dans le dernier tiers du 5ième millénaire avant notre ère. Quatre coffres étaient groupés dans la partie sud-est de l’emprise du chantier. Le cinquième était isolé, à quelques dizaines de mètres à l’ouest du groupe. Cet ensemble présente les caractères spécifiques des sépultures de type Chamblandes et vient s’ajouter à la dizaine d’ensembles funéraires connus à Sion et dans les alentours. Par leurs caractéristiques et leur excellente conservation, les sépultures de Sion-Avenue de Tourbillon contribuent de manière significative à une meilleure compréhension du phénomène Chamblandes en Valais., Summary in German, French, Italian, English
Published: 2023
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26. Are artificial neural networks useful to describe the non-adiabatic dynamics od the nitrate radical?

Author: Viel, Alexandra, Institut de Physique de Rennes (IPR), and Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS)
Subjects: [CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry, [PHYS]Physics [physics], MCTDH, Vibronic couplings, Artificial Neuron Networks ANN, Quantum dynamics
Abstract: International audience
Published: 2023

27. Analysis of the increase in technology addiction during the Covid-19 pandemic and its consequences in childhood

Author: Isadora Cucolo Oliveira, Maitê de Mello e Castro, Victoria Consulin, Ana Clara de Miranda Sartori, Gabriele Fava Martineli, Gustavo da Silva Diana, José Ricardo Carleti Monteiro, Larissa Gabrieli Franchette, Larissa Viel Martins Mesquita, Rafael Hikaru Tukiyama, Vinícius Machado Negrini, and Uderlei Doniseti Silveira Covizzi
Abstract: Childhood is composed of biological and psychosocial transitions, which enable the acquisition of motor, cognitive, and affective-social domains of development. With the onset of the covid-19 pandemic in 2020 the WHO recommended that preventive measures be taken, such as closing schools as well as public places, a fact that culminated in distancing from friends and family. This has led to a greater proximity of children to technology, thus increasing their exposure to screens. According to the Brazilian Society of Pediatrics, the use of television, tablets, and computers should be equivalent to the child's age, monitored by those responsible in order to avoid excessive use. In this context, the objective of this project was to analyze the technological addictions of 4th and 5th grade students from Elementary School I in the city of Votuporanga-SP, developed before and during the Pandemic by Covid-19, and its impacts on the children's mental health. The data were collected through a semi-structured questionnaire designed to evaluate the behavior of the children regarding the use of technology and lifestyle habits, in a qualitative and quantitative way. Our results showed that the pandemic period favored a greater access to digital equipment by children, due to their use for school activities. The increased use of cell phones created the possibility of distraction with games, videos, and participation in social networks. However, they emphasized that they prefer games involving physical activity to simply using screens. We also observed that it is of fundamental importance that parents/guardians accompany the children in stimulating family interaction.
Published: 2023
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28. Non‐invasive diagnosis of alcohol‐related steatohepatitis in patients ongoing alcohol withdrawal based on cytokeratin 18 and transient elastography

Author: Arnaud Chalin, Bruno Turlin, Ahmad Ousmen, Sophie Michalak, Johannes Mueller, Sebastian Mueller, Ludivine Legros, Edouard Bardou‐Jacquet, Jean François Viel, Michel Samson, Romain Moirand, Institut de recherche en santé, environnement et travail (Irset), Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Nutrition, Métabolismes et Cancer (NuMeCan), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), CHU Pontchaillou [Rennes], Centre Hospitalier Universitaire d'Angers (CHU Angers), PRES Université Nantes Angers Le Mans (UNAM), Universität Heidelberg [Heidelberg] = Heidelberg University, and Programme Hospitalier de Recherche Clinique, French Ministry of Health, 2012
Subjects: Hepatology, [SDV]Life Sciences [q-bio], Gastroenterology, Pharmacology (medical)
Abstract: International audience; BACKGROUND AND AIMS: The diagnosis of alcoholic steatohepatitis (ASH) is based on liver biopsy, which is costly and invasive with non-negligible morbidity. The aim of this study was to evaluate the accuracy of circulating cytokeratin 18 M65 fragment (K18-M65) alone or in association with other markers for the non-invasive diagnosis of ASH in patients ongoing alcohol withdrawal. METHODS: This study examined the serum level of K18-M65 in a test cohort of 196 patients. All patients underwent liver biopsy, transient elastography (TE) and serum collection. The diagnostic accuracy of K18-M65 alone or combined with clinico-biological data was assessed and the best defined cut-offs were validated in an independent validation cohort of 58 patients. RESULTS: K18-M65 had an area under the curve (AUC) of 0.82 (test cohort) and 0.90 (validation cohort). Using two cut-off decision points, K18-M65 was able to classify 46.9% (test cohort) and 34.5% (validation cohort) of patients with 95% sensitivity or specificity. Combining K18-M65, alpha-2-macroglobulin, TE, body mass index, and age, we created a score allowing accurate diagnosis of ASH with an AUC of 0.93 (test cohort) and 0.94 (validation cohort). This new score was able to rule out or rule in the diagnosis of steatohepatitis for probability ≤0.135 or ≥0.667 respectively in more than two-thirds of patients. CONCLUSIONS: We propose a new validated non-invasive score for the diagnosis of ASH in patients ongoing alcohol withdrawal. This score can help to identify patients that may benefit from potential therapeutics or motivate them to reduce alcohol consumption.
Published: 2023
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29. Hepatocellular carcinomas, exhibiting intratumor fibrosis, express cancer-specific extracellular matrix remodeling and WNT/TGFB signatures, associated with poor outcome

Author: Romain Desert, Wei Chen, Xiaodong Ge, Roselyne Viel, Hui Han, Dipti Athavale, Sukanta Das, Zhuolun Song, Daniel Lantvit, Luis Cano, Alexandra Naba, Orlando Musso, Natalia Nieto, University of Illinois [Chicago] (UIC), University of Illinois System, H2P2 - Histo Pathologie Hight Precision (H2P2), and Université de Rennes (UR)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )
Subjects: Hepatology, [SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and Gastroenterology
Abstract: International audience; BACKGROUND AIMS: Hepatocellular carcinoma (HCC), the third cause of cancer-related death, arises in the context of liver fibrosis (LF). Although HCC is generally poorly fibrogenic, some tumors harbor focal intratumor extracellular matrix (ECM) deposits, called fibrous nests. To date, the molecular composition and the clinical relevance of these ECM deposits has not been fully defined. APPROACH RESULTS: We performed quantitative matrisome analysis by tandem mass tags mass spectrometry (TMT-MS) in 20 human HCCs, with high- or low-grade intratumor fibrosis, and matched non-tumor (NT) tissues, as well as in 12 livers from mice treated with vehicle, CCl4 or diethylnitrosamine (DEN). We found 94 ECM proteins differentially abundant between high- and low-grade fibrous nests, including interstitial and basement membrane components, such as several collagens, glycoproteins, proteoglycans, enzymes involved in ECM stabilization and degradation, and growth factors. Pathway analysis revealed a metabolic switch in high-grade fibrosis, with enhanced glycolysis and decreased oxidative phosphorylation. Integrating our quantitative proteomics data with the transcriptomes from HCCs and NT livers (n = 2,285 samples), we identified a subgroup of fibrous nest HCCs, characterized by cancer-specific ECM remodeling, expression of the WNT/TGFB (S1) subclass signature, and poor patient outcome. Fibrous nest HCCs, abundantly expressed an 11 fibrous nest proteins’ signature, associated with poor patient outcome, by multivariate Cox analysis, and validated by multiplex immunohistochemistry. CONCLUSION: Matrisome analysis highlighted cancer-specific ECM deposits, typical of the WNT/TGFB HCC subclass, associated with poor patient outcome. Hence, histological reporting of intratumor fibrosis in HCC is of clinical relevance.
Published: 2023
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30. Copy number variants as modifiers of breast cancer risk for BRCA1/BRCA2 pathogenic variant carriers

Author: Hakkaart, Christopher, Pearson, John F, Marquart, Louise, Dennis, Joe, Wiggins, George AR, Barnes, Daniel R, Robinson, Bridget A, Mace, Peter D, Aittomäki, Kristiina, Andrulis, Irene L, Arun, Banu K, Azzollini, Jacopo, Balmaña, Judith, Barkardottir, Rosa B, Belhadj, Sami, Berger, Lieke, Blok, Marinus J, Boonen, Susanne E, Borde, Julika, Bradbury, Angela R, Brunet, Joan, Buys, Saundra S, Caligo, Maria A, Campbell, Ian, Chung, Wendy K, Claes, Kathleen BM, GEMO Study Collaborators, EMBRACE Collaborators, Collonge-Rame, Marie-Agnès, Cook, Jackie, Cosgrove, Casey, Couch, Fergus J, Daly, Mary B, Dandiker, Sita, Davidson, Rosemarie, De La Hoya, Miguel, De Putter, Robin, Delnatte, Capucine, Dhawan, Mallika, Diez, Orland, Ding, Yuan Chun, Domchek, Susan M, Donaldson, Alan, Eason, Jacqueline, Easton, Douglas F, Ehrencrona, Hans, Engel, Christoph, Evans, D Gareth, Faust, Ulrike, Feliubadaló, Lidia, Fostira, Florentia, Friedman, Eitan, Frone, Megan, Frost, Debra, Garber, Judy, Gayther, Simon A, Gehrig, Andrea, Gesta, Paul, Godwin, Andrew K, Goldgar, David E, Greene, Mark H, Hahnen, Eric, Hake, Christopher R, Hamann, Ute, Hansen, Thomas VO, Hauke, Jan, Hentschel, Julia, Herold, Natalie, Honisch, Ellen, Hulick, Peter J, Imyanitov, Evgeny N, SWE-BRCA Investigators, KConFab Investigators, HEBON Investigators, Isaacs, Claudine, Izatt, Louise, Izquierdo, Angel, Jakubowska, Anna, James, Paul A, Janavicius, Ramunas, John, Esther M, Joseph, Vijai, Karlan, Beth Y, Kemp, Zoe, Kirk, Judy, Konstantopoulou, Irene, Koudijs, Marco, Kwong, Ava, Laitman, Yael, Lalloo, Fiona, Lasset, Christine, Lautrup, Charlotte, Lazaro, Conxi, Legrand, Clémentine, Leslie, Goska, Lesueur, Fabienne, Mai, Phuong L, Manoukian, Siranoush, Mari, Véronique, Martens, John WM, McGuffog, Lesley, Mebirouk, Noura, Meindl, Alfons, Miller, Austin, Montagna, Marco, Moserle, Lidia, Mouret-Fourme, Emmanuelle, Musgrave, Hannah, Nambot, Sophie, Nathanson, Katherine L, Neuhausen, Susan L, Nevanlinna, Heli, Yie, Joanne Ngeow Yuen, Nguyen-Dumont, Tu, Nikitina-Zake, Liene, Offit, Kenneth, Olah, Edith, Olopade, Olufunmilayo I, Osorio, Ana, Ott, Claus-Eric, Park, Sue K, Parsons, Michael T, Pedersen, Inge Sokilde, Peixoto, Ana, Perez-Segura, Pedro, Peterlongo, Paolo, Pocza, Timea, Radice, Paolo, Ramser, Juliane, Rantala, Johanna, Rodriguez, Gustavo C, Rønlund, Karina, Rosenberg, Efraim H, Rossing, Maria, Schmutzler, Rita K, Shah, Payal D, Sharif, Saba, Sharma, Priyanka, Side, Lucy E, Simard, Jacques, Singer, Christian F, Snape, Katie, Steinemann, Doris, Stoppa-Lyonnet, Dominique, Sutter, Christian, Tan, Yen Yen, Teixeira, Manuel R, Teo, Soo Hwang, Thomassen, Mads, Thull, Darcy L, Tischkowitz, Marc, Toland, Amanda E, Trainer, Alison H, Tripathi, Vishakha, Tung, Nadine, Van Engelen, Klaartje, Van Rensburg, Elizabeth J, Vega, Ana, Viel, Alessandra, Walker, Lisa, Weitzel, Jeffrey N, Wevers, Marike R, Chenevix-Trench, Georgia, Spurdle, Amanda B, Antoniou, Antonis C, Walker, Logan C, Pearson, John F [0000-0001-5607-4517], Dennis, Joe [0000-0003-4591-1214], Barnes, Daniel R [0000-0002-3781-7570], Mace, Peter D [0000-0003-2175-9537], Andrulis, Irene L [0000-0002-4226-6435], Azzollini, Jacopo [0000-0002-9364-9778], Blok, Marinus J [0000-0002-7935-5933], Brunet, Joan [0000-0003-1945-3512], Campbell, Ian [0000-0002-7773-4155], Chung, Wendy K [0000-0003-3438-5685], Claes, Kathleen BM [0000-0003-0841-7372], Dandiker, Sita [0000-0003-3837-7690], de la Hoya, Miguel [0000-0002-8113-1410], de Putter, Robin [0000-0001-9410-8941], Easton, Douglas F [0000-0003-2444-3247], Ehrencrona, Hans [0000-0002-5589-3622], Feliubadaló, Lidia [0000-0002-1736-0112], Gayther, Simon A [0000-0001-7937-5443], Gesta, Paul [0000-0002-4410-8668], Godwin, Andrew K [0000-0002-3987-9580], Greene, Mark H [0000-0003-1852-9239], Hauke, Jan [0000-0001-8236-4075], Hulick, Peter J [0000-0001-8397-4078], Isaacs, Claudine [0000-0002-9646-1260], Izatt, Louise [0000-0003-1258-4843], Izquierdo, Angel [0000-0003-2004-3246], Jakubowska, Anna [0000-0002-5650-0501], James, Paul A [0000-0002-4361-4657], Joseph, Vijai [0000-0002-7933-151X], Karlan, Beth Y [0000-0002-9451-2933], Konstantopoulou, Irene [0000-0002-0470-0309], Lazaro, Conxi [0000-0002-7198-5906], Leslie, Goska [0000-0001-5756-6222], Lesueur, Fabienne [0000-0001-7404-4549], Martens, John WM [0000-0002-3428-3366], Miller, Austin [0000-0001-9739-8462], Nambot, Sophie [0000-0002-9630-5049], Nathanson, Katherine L [0000-0002-6740-0901], Neuhausen, Susan L [0000-0001-5053-0390], Nevanlinna, Heli [0000-0002-0916-2976], Yie, Joanne Ngeow Yuen [0000-0003-1558-3627], Nikitina-Zake, Liene [0000-0003-2491-5187], Olopade, Olufunmilayo I [0000-0002-9936-1599], Osorio, Ana [0000-0001-8124-3984], Ott, Claus-Eric [0000-0003-3627-3791], Park, Sue K [0000-0001-5002-9707], Parsons, Michael T [0000-0003-3242-8477], Pedersen, Inge Sokilde [0000-0002-9902-8040], Peterlongo, Paolo [0000-0001-6951-6855], Radice, Paolo [0000-0001-6298-4111], Rosenberg, Efraim H [0000-0002-3859-6941], Simard, Jacques [0000-0001-6906-3390], Steinemann, Doris [0000-0001-8797-0816], Sutter, Christian [0000-0003-4051-5888], Tan, Yen Yen [0000-0003-1063-5352], Teixeira, Manuel R [0000-0002-4896-5982], Teo, Soo Hwang [0000-0002-0444-590X], Tischkowitz, Marc [0000-0002-7880-0628], Toland, Amanda E [0000-0002-0271-1792], Tripathi, Vishakha [0000-0001-8118-8364], van Rensburg, Elizabeth J [0000-0003-2077-230X], Vega, Ana [0000-0002-7416-5137], Viel, Alessandra [0000-0003-2804-0840], Weitzel, Jeffrey N [0000-0001-6714-092X], Wevers, Marike R [0000-0001-8008-6008], Spurdle, Amanda B [0000-0003-1337-7897], Walker, Logan C [0000-0003-0018-3719], and Apollo - University of Cambridge Repository
Subjects: Heterozygote, DNA Copy Number Variations, 45/43, 45/22, 13/107, 45/23, 13/106, Breast Neoplasms, 13, 14, 13/44, 631/67/68, 38/89, Humans, Genetic Predisposition to Disease, RNA, Messenger, 45/90, 38/109, 64, BRCA2 Protein, 45, BRCA1 Protein, article, 45/77, 692/4028/67, 38/35, 14/63, Female
Abstract: The contribution of germline copy number variants (CNVs) to risk of developing cancer in individuals with pathogenic BRCA1 or BRCA2 variants remains relatively unknown. We conducted the largest genome-wide analysis of CNVs in 15,342 BRCA1 and 10,740 BRCA2 pathogenic variant carriers. We used these results to prioritise a candidate breast cancer risk-modifier gene for laboratory analysis and biological validation. Notably, the HR for deletions in BRCA1 suggested an elevated breast cancer risk estimate (hazard ratio (HR) = 1.21), 95% confidence interval (95% CI = 1.09-1.35) compared with non-CNV pathogenic variants. In contrast, deletions overlapping SULT1A1 suggested a decreased breast cancer risk (HR = 0.73, 95% CI 0.59-0.91) in BRCA1 pathogenic variant carriers. Functional analyses of SULT1A1 showed that reduced mRNA expression in pathogenic BRCA1 variant cells was associated with reduced cellular proliferation and reduced DNA damage after treatment with DNA damaging agents. These data provide evidence that deleterious variants in BRCA1 plus SULT1A1 deletions contribute to variable breast cancer risk in BRCA1 carriers., C12292/A20861 PPRPGM-Nov20\100002
Published: 2022
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31. Preclinical evaluation of targeted therapies in Sdhb-mutated tumors

Author: Sophie Moog, Betty Salgues, Yasmine Braik-Djellas, Thomas Viel, Daniel Balvay, Gwennhael Autret, Estelle Robidel, Anne-Paule Gimenez-Roqueplo, Bertrand Tavitian, Charlotte Lussey-Lepoutre, Judith Favier, Favier, Judith, Paris-Centre de Recherche Cardiovasculaire (PARCC (UMR_S 970/ U970)), Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), and Université Paris Cité (UPCité)
Subjects: [SDV.MHEP.EM] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, Cancer Research, HIF2α inhibitors, Endocrinology, Diabetes and Metabolism, Adrenal Gland Neoplasms, Antineoplastic Agents, Succinates, Pheochromocytoma, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, succinate, targeted therapies, Paraganglioma, Succinate Dehydrogenase, Mice, Endocrinology, Oncology, Fluorodeoxyglucose F18, Mutation, Sunitinib, Animals, Humans, metastatic pheochromocytoma and paraganglioma, preclinical model
Abstract: Therapies for metastatic SDHB-dependent pheochromocytoma and paraganglioma (PPGL) are limited and poorly efficient. New targeted therapies and identification of early non-invasive biomarkers of response are thus urgently needed for these patients. We characterized an in vivo allograft model of spontaneously immortalized murine chromaffin cells (imCC) with inactivation of the Sdhb gene by dynamic contrast-enhanced MRI (DCE-MRI) and 18FDG-PET. We evaluated the response to several therapies: IACS-010759 (mitochondrial respiratory chain complex I inhibitor), sunitinib (tyrosine kinase inhibitor with anti-angiogenic activity), talazoparib (poly ADP ribose polymerase (PARP) inhibitor) combined or not to temozolomide (alkylating agent), pharmacological inhibitors of HIF2a (PT2385 and PT2977 (belzutifan)) and molecular inactivation of HIF2a (imCC Sdhb−/− shHIF2a). Multimodal imaging was performed, including magnetic resonance spectroscopy (1H-MRS) to monitor the level of succinate in vivo. The allografted model of Sdhb−/− imCC reflected SDHB-deficient tumors, with increased angiogenesis and a particular avidity for 18FDG. After 14 days of treatment, IACS-010759, sunitinib and talazoparib at high doses allowed a significant reduction of the tumor volumes. In contrast to the tumor growth inhibition observed in Sdhb−/− shHIF2a imCC tumors, pharmacological inhibitors of HIF2a (PT2385 and belzutifan) showed no antitumor action in this model, alone or in combination with sunitinib. 1H-MRS, but not DCE-MRI, enabled the monitoring response to sunitinib, which was the best treatment in this study, promoting a decrease in succinate levels detected in vivo. This study paves the way for new therapeutic options and reveals a potential new early biomarker of response to treatment in SDHB-dependent PPGL.
Published: 2022
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32. Cerebrospinal Fluid Shunt Infections: A Multicenter Pediatric Study

Author: Alastair, McAlpine, Joan L, Robinson, Michelle, Barton, Archana, Balamohan, H Dele, Davies, Gwenn, Skar, Marie-Astrid, Lefebvre, Ahmed, Almadani, Dolores, Freire, Nicole, Le Saux, Jennifer, Bowes, Jocelyn A, Srigley, Patrick, Passarelli, John, Bradley, Sarah, Khan, Rupeena, Purewal, Isabelle, Viel-Thériault, Adrianna, Ranger, and Michael T, Hawkes
Subjects: Male, Methicillin-Resistant Staphylococcus aureus, Microbiology (medical), Staphylococcus aureus, Staphylococcus, Infant, Staphylococcal Infections, Cerebrospinal Fluid Shunts, Anti-Bacterial Agents, Infectious Diseases, Vancomycin, Child, Preschool, Gram-Negative Bacteria, Pediatrics, Perinatology and Child Health, Humans, Female, Child, Retrospective Studies
Abstract: Infections complicate 5%-10% of cerebrospinal fluid (CSF) shunts. We aimed to describe the characteristics and contemporary pathogens of shunt infections in children in Canada and the United States.Descriptive case series at tertiary care hospitals in Canada (N = 8) and the United States (N = 3) of children up to 18 years of age with CSF shunt infections from July 1, 2013, through June 30, 2019.There were 154 children (43% female, median age 2.7 years, 50% premature) with ≥1 CSF shunt infections. Median time between shunt placement and infection was 54 days (interquartile range, 24 days-2.3 years). Common pathogens were coagulase-negative staphylococci (N = 42; 28%), methicillin-susceptible Staphylococcus aureus (N = 24; 16%), methicillin-resistant S. aureus (N = 9; 5.9%), Pseudomonas aeruginosa (N = 9; 5.9%) and other Gram-negative bacilli (N = 14; 9.0%). Significant differences between pathogens were observed, including timing of infection (P = 0.023) and CSF leukocyte count (P = 0.0019); however, differences were not sufficient to reliably predict the causative organism based on the timing of infection or discriminate P. aeruginosa from other pathogens based on clinical features. Empiric antibiotic regimens, which included vancomycin (71%), cefotaxime or ceftriaxone (29%) and antipseudomonal beta-lactams (33%), were discordant with the pathogen isolated in five cases. There was variability between sites in the distribution of pathogens and choice of empiric antibiotics. Nine children died; 4 (44%) deaths were attributed to shunt infection.Staphylococci remain the most common cause of CSF shunt infections, although antibiotic resistant Gram-negative bacilli occur and cannot be reliably predicted based on clinical characteristics.
Published: 2022
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33. Musées de société, musées hybrides : regards croisés sur les mutations québécoises

Author: Jean-François Leclerc, Katy Tari, and Annette Viel
Subjects: Cultural Studies, Visual Arts and Performing Arts, Museology, Conservation
Published: 2022
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34. Mutational Studies of the Mersacidin Leader Reveal the Function of Its Unique Two-Step Leader Processing Mechanism

Author: Jakob Viel, Oscar Kuipers, and Molecular Genetics
Subjects: E. coli, Biomedical Engineering, heterologous expression, General Medicine, Protein Sorting Signals, leader, Biochemistry, Genetics and Molecular Biology (miscellaneous), lanthipeptide, Bacteriocins, Escherichia coli, RiPP, mersacidin, Amino Acid Sequence, mutation, Peptides, Protein Processing, Post-Translational, Peptide Hydrolases
Abstract: The class II lanthipeptide mersacidin, a ribosomally synthesized and post-translationally modified peptide (RiPP), displays unique intramolecular structures, including a very small lanthionine ring. When applied in the growing field of RiPP engineering, these can add unique features to new-to-nature compounds with novel properties. Recently, a heterologous expression system for mersacidin in Escherichia coli was developed to add its modification enzymes to the RiPP engineering toolbox and further explore mersacidin biosynthesis and leader-processing. The dedicated mersacidin transporter and leader protease MrsT was shown to cleave the leader peptide only partially upon export, transporting GDMEAA-mersacidin out of the cell. The extracellular Bacillus amyloliquefaciens protease AprE was shown to release active mersacidin in a second leader-processing step after transport. The conserved LanT cleavage site in the mersacidin leader is present in many other class II lanthipeptides. In contrast to mersacidin, the leader of these peptides is fully processed in one step. This difference with mersacidin leader-processing raises fundamentally interesting questions about the specifics of mersacidin modification and processing, which is also crucial for its application in RiPP engineering. Here, mutational studies of the mersacidin leader-core interface were performed to answer these questions. Results showed the GDMEAA sequence is crucial for both mersacidin modification and leader processing, revealing a unique leader layout in which a LanM recognition site is positioned downstream of the conserved leader-protease LanT cleavage site. Moreover, by identifying residues and regions that are crucial for mersacidin-type modifications, the wider application of mersacidin modifications in RiPP engineering has been enabled.
Published: 2022
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35. Conocimiento Especializado de Potenciación movilizado por docentes a partir de una Investigación Basada en Design

Author: Henrique Rizek Elias, Daniele Peres da Silva Martelozo, Laís Cristina Viel Gereti, and Susana de Fátima Lopes
Subjects: Applied Mathematics, General Mathematics
Abstract: En este artículo presentamos los resultados de la fase inicial de una investigación desarrollada por un grupo de estudio e investigación en el ámbito de una Maestría Profesional (MP), basada y enmarcada en la metodología de la Investigación Basada en el Diseño (IBD). Específicamente, en este trabajo, nos enfocamos en los primeros cuatro encuentros dedicados a discusiones teóricas sobre el contenido matemático de la potenciación, con el objetivo de analizar el Conocimiento Especializado del Contenido (SCK) movilizado/refinado por los docentes mientras trabajan colaborativamente en la etapa de preparación de un IBD y, luego, elaborar una conjetura sobre la dimensión del contenido de potenciación para el 6° año de primaria. A partir de los datos producidos en las grabaciones de las reuniones del grupo de estudio y investigación, concluimos que la experiencia brindada por el IBD favoreció la producción de conocimiento para los docentes, ya que lograron movilizar/refinar su SCK respecto a la potenciación cuando se permitieron entender la potenciación como una representación y cuando pudieron ampliar su perspectiva sobre el tema matemático, en la dirección de establecer relaciones entre la aritmética (trabajada en los primeros años) y el álgebra, a través del pensamiento algebraico, proporcionando un entorno favorable para nuevas reflexiones y aprendiendo sobre pensamiento algebraico y la potenciación.
Published: 2022
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36. Euclid preparation - XVII. Cosmic Dawn Survey: Spitzer Space Telescope observations of the Euclid deep fields and calibration fields

Author: Euclid Collaboration, Moneti, A., McCracken, H. J., Shuntov, M., Kauffmann, O. B., Capak, P., Davidzon, I., Ilbert, O., Scarlata, C., Toft, S., Weaver, J., Pires, S., Poncet, M., Popa, L., POZZETTI, Lucia, Raison, F., Rebolo, R., Rhodes, J., Rix, H., Roncarelli, M., Rossetti, E., Chary, R., Saglia, R., Schneider, P., Secroun, A., Seidel, G., Serrano, S., Sirignano, C., Sirri, G., Stanco, L., Tallada-Crespí, P., Taylor, A. N., Cuby, J., Tereno, I., Toledo-Moreo, R., Torradeflot, F., Wang, Y., Welikala, N., Weller, J., Zamorani, G., Zoubian, J., ANDREON, Stefano, BARDELLI, Sandro, Faisst, A. L., Camera, S., Graciá-Carpio, J., Medinaceli, E., Mei, S., Polenta, G., Romelli, Erik, Sureau, F., Tenti, M., Vassallo, T., ZACCHEI, Andrea, Masters, D. C., ZUCCA, Elena, Baccigalupi, C., Balaguera-Antolínez, A., Bernardeau, F., BIVIANO, ANDREA, BOLZONELLA, MICOL, Bozzo, E., BURIGANA, CARLO, Cabanac, R., CAPPI, Alberto, McPartland, C., Carvalho, C. S., Casas, S., Castignani, G., Colodro-Conde, C., Coupon, J., Courtois, H. M., Di Ferdinando, D., FARINA, Maria, FINELLI, FABIO, Flose-Reimberg, P., Mobasher, B., Fotopoulou, S., GALEOTTA, Samuele, Ganga, K., Garcia-Bellido, J., Gaztanaga, E., Gozaliasl, G., Hook, I., Joachimi, B., Kansal, V., Keihanen, E., Sanders, D. B., Kirkpatrick, C. C., Lindholm, V., Mainetti, G., Maino, D., Maoli, R., Martinelli, M., Martinet, N., Maturi, M., Metcalf, R. B., MORGANTE, GIANLUCA, SCARAMELLA, Roberto, Morisset, N., Nucita, A., Patrizii, L., Potter, D., Renzi, A., RICCIO, GIUSEPPE, Sánchez, A. G., Sapone, D., Schirmer, M., Schultheis, M., Stern, D., Scottez, V., SEFUSATTI, Emiliano, Teyssier, R., Tubio, O., Tutusaus, I., Valiviita, J., VIEL, MATTEO, Hildebrandt, H., Szapudi, I., Teplitz, H., Zalesky, L., Amara, A., AURICCHIO, NATALIA, Bodendorf, C., BONINO, Donata, Branchini, Enzo, Brau-Nogue, S., BRESCIA, Massimo, Brinchmann, J., Capobianco, Vito, CARBONE, Carmelita, Carretero, J., Castander, F. J., CASTELLANO, MARCO, CAVUOTI, STEFANO, Cimatti, A., Cledassou, R., Congedo, G., Conselice, C. J., Conversi, L., Copin, Y., CORCIONE, Leonardo, Costille, A., Cropper, M., Da Silva, A., Degaudenzi, H., Douspis, M., Dubath, F., Duncan, C. A. J., Dupac, X., Dusini, S., Farrens, S., Ferriol, S., Fosalba, P., FRAILIS, Marco, FRANCESCHI, ENRICO, FUMANA, Marco, GARILLI, BIANCA MARIA ROSA, Gillis, B., GIOCOLI, Carlo, Granett, B. R., GRAZIAN, Andrea, Grupp, F., Haugan, S. V. H., Hoekstra, H., Holmes, W., Hormuth, F., Hudelot, P., Jahnke, K., Kermiche, S., Kiessling, A., Kilbinger, M., Kitching, T., Kohley, R., Kümmel, M., Kunz, M., Kurki-Suonio, H., LIGORI, Sebastiano, Lilje, P. B., Lloro, I., MAIORANO, Elisabetta, MANSUTTI, Oriana, Marggraf, O., Markovic, K., Marulli, F., Massey, R., Maurogordato, S., MENEGHETTI, MASSIMO, MERLIN, Emiliano, Meylan, G., Moresco, M., Moscardini, L., Munari, Emiliano, Niemi, S. M., Padilla, C., Paltani, S., Pasian, F., Pedersen, K., Institut d'Astrophysique de Paris (IAP), Institut national des sciences de l'Univers (INSU - CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Astrophysique de Marseille (LAM), Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Centre National d'Études Spatiales [Toulouse] (CNES), Institut de Physique des 2 Infinis de Lyon (IP2I Lyon), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut d'astrophysique spatiale (IAS), Université Paris-Sud - Paris 11 (UP11)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Centre National d’Études Spatiales [Paris] (CNES), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Institut de recherche en astrophysique et planétologie (IRAP), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), Institut de Ciencies de l'Espai [Barcelona] (ICE-CSIC), Consejo Superior de Investigaciones Científicas [Madrid] (CSIC), Institut d'Estudis Espacials de Catalunya (IEEC-CSIC), Centre de Calcul de l'IN2P3 (CC-IN2P3), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Euclid Collaboration, Moneti, A., Mccracken, H. J., Shuntov, M., Kauffmann, O. B., Capak, P., Davidzon, I., Ilbert, O., Scarlata, C., Toft, S., Weaver, J., Chary, R., Cuby, J., Faisst, A. L., Masters, D. C., Mcpartland, C., Mobasher, B., Sanders, D. B., Scaramella, R., Stern, D., Szapudi, I., Teplitz, H., Zalesky, L., Amara, A., Auricchio, N., Bodendorf, C., Bonino, D., Branchini, E., Brau-Nogue, S., Brescia, M., Brinchmann, J., Capobianco, V., Carbone, C., Carretero, J., Castander, F. J., Castellano, M., Cavuoti, S., Cimatti, A., Cledassou, R., Congedo, G., Conselice, C. J., Conversi, L., Copin, Y., Corcione, L., Costille, A., Cropper, M., Da Silva, A., Degaudenzi, H., Douspis, M., Dubath, F., Duncan, C. A. J., Dupac, X., Dusini, S., Farrens, S., Ferriol, S., Fosalba, P., Frailis, M., Franceschi, E., Fumana, M., Garilli, B., Gillis, B., Giocoli, C., Granett, B. R., Grazian, A., Grupp, F., Haugan, S. V. H., Hoekstra, H., Holmes, W., Hormuth, F., Hudelot, P., Jahnke, K., Kermiche, S., Kiessling, A., Kilbinger, M., Kitching, T., Kohley, R., K??mmel, M., Kunz, M., Kurki-Suonio, H., Ligori, S., Lilje, P. B., Lloro, I., Maiorano, E., Mansutti, O., Marggraf, O., Markovic, K., Marulli, F., Massey, R., Maurogordato, S., Meneghetti, M., Merlin, E., Meylan, G., Moresco, M., Moscardini, L., Munari, E., Niemi, S. M., Padilla, C., Paltani, S., Pasian, F., Pedersen, K., Pires, S., Poncet, M., Popa, L., Pozzetti, L., Raison, F., Rebolo, R., Rhodes, J., Rix, H., Roncarelli, M., Rossetti, E., Saglia, R., Schneider, P., Secroun, A., Seidel, G., Serrano, S., Sirignano, C., Sirri, G., Stanco, L., Tallada-Cresp??, P., Taylor, A. N., Tereno, I., Toledo-Moreo, R., Torradeflot, F., Wang, Y., Welikala, N., Weller, J., Zamorani, G., Zoubian, J., Andreon, S., Bardelli, S., Camera, S., Graci??-Carpio, J., Medinaceli, E., Mei, S., Polenta, G., Romelli, E., Sureau, F., Tenti, M., Vassallo, T., Zacchei, A., Zucca, E., Baccigalupi, C., Balaguera-Antol??nez, A., Bernardeau, F., Biviano, A., Bolzonella, M., Bozzo, E., Burigana, C., Cabanac, R., Cappi, A., Carvalho, C. S., Casas, S., Castignani, G., Colodro-Conde, C., Coupon, J., Courtois, H. M., Di Ferdinando, D., Farina, M., Finelli, F., Flose-Reimberg, P., Fotopoulou, S., Galeotta, S., Ganga, K., Garcia-Bellido, J., Gaztanaga, E., Gozaliasl, G., Hook, I., Joachimi, B., Kansal, V., Keihanen, E., Kirkpatrick, C. C., Lindholm, V., Mainetti, G., Maino, D., Maoli, R., Martinelli, M., Martinet, N., Maturi, M., Metcalf, R. B., Morgante, G., Morisset, N., Nucita, A., Patrizii, L., Potter, D., Renzi, A., Riccio, G., S??nchez, A. G., Sapone, D., Schirmer, M., Schultheis, M., Scottez, V., Sefusatti, E., Teyssier, R., Tubio, O., Tutusaus, I., Valiviita, J., Viel, M., Hildebrandt, H., Department of Physics, Research Program in Systems Oncology, Helsinki Institute of Physics, UAM. Departamento de Física Teórica, Moneti A., Mccracken H.J., Shuntov M., Kauffmann O.B., Capak P., Davidzon I., Ilbert O., Scarlata C., Toft S., Weaver J., Chary R., Cuby J., Faisst A.L., Masters D.C., Mcpartland C., Mobasher B., Sanders D.B., Scaramella R., Stern D., Szapudi I., Teplitz H., Zalesky L., Amara A., Auricchio N., Bodendorf C., Bonino D., Branchini E., Brau-Nogue S., Brescia M., Brinchmann J., Capobianco V., Carbone C., Carretero J., Castander F.J., Castellano M., Cavuoti S., Cimatti A., Cledassou R., Congedo G., Conselice C.J., Conversi L., Copin Y., Corcione L., Costille A., Cropper M., Da Silva A., Degaudenzi H., Douspis M., Dubath F., Duncan C.A.J., Dupac X., Dusini S., Farrens S., Ferriol S., Fosalba P., Frailis M., Franceschi E., Fumana M., Garilli B., Gillis B., Giocoli C., Granett B.R., Grazian A., Grupp F., Haugan S.V.H., Hoekstra H., Holmes W., Hormuth F., Hudelot P., Jahnke K., Kermiche S., Kiessling A., Kilbinger M., Kitching T., Kohley R., Kummel M., Kunz M., Kurki-Suonio H., Ligori S., Lilje P.B., Lloro I., Maiorano E., Mansutti O., Marggraf O., Markovic K., Marulli F., Massey R., Maurogordato S., Meneghetti M., Merlin E., Meylan G., Moresco M., Moscardini L., Munari E., Niemi S.M., Padilla C., Paltani S., Pasian F., Pedersen K., Pires S., Poncet M., Popa L., Pozzetti L., Raison F., Rebolo R., Rhodes J., Rix H., Roncarelli M., Rossetti E., Saglia R., Schneider P., Secroun A., Seidel G., Serrano S., Sirignano C., Sirri G., Stanco L., Tallada-Crespi P., Taylor A.N., Tereno I., Toledo-Moreo R., Torradeflot F., Wang Y., Welikala N., Weller J., Zamorani G., Zoubian J., Andreon S., Bardelli S., Camera S., Gracia-Carpio J., Medinaceli E., Mei S., Polenta G., Romelli E., Sureau F., Tenti M., Vassallo T., Zacchei A., Zucca E., Baccigalupi C., Balaguera-Antolinez A., Bernardeau F., Biviano A., Bolzonella M., Bozzo E., Burigana C., Cabanac R., Cappi A., Carvalho C.S., Casas S., Castignani G., Colodro-Conde C., Coupon J., Courtois H.M., Di Ferdinando D., Farina M., Finelli F., Flose-Reimberg P., Fotopoulou S., Galeotta S., Ganga K., Garcia-Bellido J., Gaztanaga E., Gozaliasl G., Hook I., Joachimi B., Kansal V., Keihanen E., Kirkpatrick C.C., Lindholm V., Mainetti G., Maino D., Maoli R., Martinelli M., Martinet N., Maturi M., Metcalf R.B., Morgante G., Morisset N., Nucita A., Patrizii L., Potter D., Renzi A., Riccio G., Sanchez A.G., Sapone D., Schirmer M., Schultheis M., Scottez V., Sefusatti E., Teyssier R., Tubio O., Tutusaus I., Valiviita J., Viel M., Hildebrandt H., Kummel, M., Tallada-Crespi, P., Gracia-Carpio, J., Balaguera-Antolinez, A., and Sanchez, A. G.
Subjects: SAMPLE, Large-scale structure of Universe, DATA RELEASE, Formation, Surveys, observations, Dark energy, Dark matter, Galaxy: formation, Large-scale structure of Universe, Surveys [Cosmology], kosmologia, Astrophysics, Cosmology: observation, dark matter, galaksijoukot, pimeä aine, surveys, Dark energy, Dark matter, observations [Cosmology], dark energy, Observations, LEGACY SURVEY, Astrophysics of Galaxies, Física, Astronomy and Astrophysics, 115 Astronomy, Space science, EVOLUTION, Cosmology, galaksit, GALAXIES, Cosmology: observations, Galaxy: formation, Galaxy, formation [Galaxy], Space and Planetary Science, cosmology: observations, large-scale structure of Universe, pimeä energia, Cosmology and Nongalactic Astrophysics, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph]
Abstract: Artículo escrito por un elevado núnmero de autores, sólo se referencian el qque aparece en primer lugar, los autores pertenecientes a la UAM y el nombre del grupo de colaboración, si lo hubiere, We present a new infrared survey covering the three Euclid deep fields and four other Euclid calibration fields using Spitzer Space Telescope's Infrared Array Camera (IRAC). We combined these new observations with all relevant IRAC archival data of these fields in order to produce the deepest possible mosaics of these regions. In total, these observations represent nearly 11 % of the total Spitzer Space Telescope mission time. The resulting mosaics cover a total of approximately 71.5 deg2 in the 3.6 and 4.5 μm bands, and approximately 21.8 deg2 in the 5.8 and 8 μm bands. They reach at least 24 AB magnitude (measured to 5σ, in a 2″.5 aperture) in the 3.6 μm band and up to ∼5 mag deeper in the deepest regions. The astrometry is tied to the Gaia astrometric reference system, and the typical astrometric uncertainty for sources with 16 "< "[3.6]< 19 is ≲ 0″.15. The photometric calibration is in excellent agreement with previous WISE measurements. We extracted source number counts from the 3.6 μm band mosaics, and they are in excellent agreement with previous measurements. Given that the Spitzer Space Telescope has now been decommissioned, these mosaics are likely to be the definitive reduction of these IRAC data. This survey therefore represents an essential first step in assembling multi-wavelength data on the Euclid deep fields, which are set to become some of the premier fields for extragalactic astronomy in the 2020s
Published: 2022
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37. Euclid preparation XV. Forecasting cosmological constraints for the Euclid and CMB joint analysis

Author: Euclid Collaboration, Ilić, S., Aghanim, N., Baccigalupi, C., BERMEJO CLIMENT, JOSE RAMON, Fabbian, G., Legrand, L., PAOLETTI, DANIELA, Ballardini, M., Archidiacono, M., Douspis, M., Kubik, B., Kümmel, M., Kurki-Suonio, H., Laureijs, R., LIGORI, Sebastiano, Lilje, P. B., Lloro, I., MANSUTTI, Oriana, Marggraf, O., Marulli, F., FINELLI, FABIO, Massey, R., Maurogordato, S., MENEGHETTI, MASSIMO, MERLIN, Emiliano, Meylan, G., Moresco, M., Morin, B., Moscardini, L., Munari, Emiliano, Niemi, S. M., Ganga, K., Padilla, C., Paltani, S., Pasian, F., Pedersen, K., Percival, W., Pires, S., Poncet, M., Popa, L., POZZETTI, Lucia, Raison, F., Hernández-Monteagudo, C., Rebolo, R., Rhodes, J., Roncarelli, M., Rossetti, E., Saglia, R., SCARAMELLA, Roberto, Schneider, P., Secroun, A., Seidel, G., Serrano, S., LATTANZI, Mario Gilberto, Sirignano, C., Starck, J. L., Tallada-Crespí, P., Taylor, A. N., Tereno, I., Toledo-Moreo, R., Torradeflot, F., Valentijn, E. A., VALENZIANO, LUCA, Verdoes Kleijn, G. A., Marinucci, D., Wang, Y., Welikala, N., Weller, J., Zamorani, G., Zoubian, J., Medinaceli, E., Mei, S., Rosset, C., Sureau, F., Vassallo, T., Migliaccio, M., ZACCHEI, Andrea, ANDREON, Stefano, Balaguera-Antolínez, A., Baldi, M., BARDELLI, Sandro, BIVIANO, ANDREA, BORGANI, STEFANO, Bozzo, E., BURIGANA, CARLO, Cabanac, R., CARBONE, Carmelita, CAPPI, Alberto, Carvalho, C. S., Castignani, G., Colodro-Conde, C., Coupon, J., Courtois, H. M., Cuby, J., de la Torre, S., Di Ferdinando, D., Dole, H., Casas, S., FARINA, Maria, Ferreira, P. G., Flose-Reimberg, P., GALEOTTA, Samuele, Gozaliasl, G., Graciá-Carpio, J., Keihanen, E., Kirkpatrick, C. C., Lindholm, V., Mainetti, G., Martinelli, M., Maino, D., Martinet, N., Maturi, M., Metcalf, R. B., MORGANTE, GIANLUCA, Neissner, C., Nightingale, J., Nucita, A. A., Potter, D., RICCIO, GIUSEPPE, Tutusaus, I., Romelli, Erik, Schirmer, M., Schultheis, M., Scottez, V., Teyssier, R., Tramacere, A., Valiviita, J., VIEL, MATTEO, Whittaker, L., ZUCCA, Elena, Natoli, P., Ntelis, P., Pagano, L., Wenzl, L., GRUPPUSO, ALESSANDRO, Kitching, T., Langer, M., Mauri, N., Patrizii, L., Renzi, A., Sirri, G., Stanco, L., Tenti, M., Vielzeuf, P., Lacasa, F., Polenta, G., Yankelevich, V., Blanchard, A., Sakr, Z., Pourtsidou, A., Camera, S., CARDONE, Vincenzo Fabrizio, Kilbinger, M., Kunz, M., Markovic, K., Pettorino, V., Sánchez, A. G., Sapone, D., Amara, A., AURICCHIO, NATALIA, Bender, R., Bodendorf, C., BONINO, Donata, Branchini, Enzo, BRESCIA, Massimo, Brinchmann, J., Capobianco, Vito, Carretero, J., Castander, F. J., CASTELLANO, MARCO, CAVUOTI, STEFANO, Cimatti, A., Cledassou, R., Congedo, G., Conselice, C. J., Conversi, L., Copin, Y., CORCIONE, Leonardo, Costille, A., Cropper, M., Da Silva, A., Degaudenzi, H., Dubath, F., Duncan, C. A. J., Dupac, X., Dusini, S., Ealet, A., Farrens, S., Fosalba, P., FRAILIS, Marco, FRANCESCHI, ENRICO, FRANZETTI, PAOLO, FUMANA, Marco, GARILLI, BIANCA MARIA ROSA, Gillard, W., Gillis, B., GIOCOLI, Carlo, GRAZIAN, Andrea, Grupp, F., Guzzo, L., Haugan, S. V. H., Hoekstra, H., Holmes, W., Hormuth, F., Hudelot, P., Jahnke, K., Kermiche, S., Kiessling, A., Kohley, R., Institut d'astrophysique spatiale (IAS), Université Paris-Sud - Paris 11 (UP11)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS)-Centre National d’Études Spatiales [Paris] (CNES), Scuola Internazionale Superiore di Studi Avanzati / International School for Advanced Studies (SISSA / ISAS), Universidad de La Laguna [Tenerife - SP] (ULL), Instituto de Astrofisica de Canarias (IAC), Istituto di Astrofisica Spaziale e Fisica cosmica - Bologna (IASF-Bo), Istituto Nazionale di Astrofisica (INAF), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), International Center for Relativistic Astrophysics (ICRA), Università degli Studi di Roma, Dipartimento di Matematica [Roma II] (DIPMAT), Università degli Studi di Roma Tor Vergata [Roma], Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Centre National d’Études Spatiales [Paris] (CNES), Institut de recherche en astrophysique et planétologie (IRAP), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), Astrophysique Interprétation Modélisation (AIM (UMR7158 / UMR_E_9005 / UM_112)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Université Paris-Sud - Paris 11 (UP11), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Centre National d'Études Spatiales [Toulouse] (CNES), Herschel Science Center [Madrid], European Space Astronomy Centre (ESAC), Agence Spatiale Européenne = European Space Agency (ESA)-Agence Spatiale Européenne = European Space Agency (ESA), Institut de Physique des 2 Infinis de Lyon (IP2I Lyon), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Astrophysique de Marseille (LAM), Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS), Centre d'étude spatiale des rayonnements (CESR), Université Paris-Saclay, Université Paris Cité (UPCité), CEA- Saclay (CEA), Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Joseph Louis LAGRANGE (LAGRANGE), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS), Centre de Calcul de l'IN2P3 (CC-IN2P3), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Euclid Collaboration, Astronomy, Intelligent Systems, Ilic S., Aghanim N., Baccigalupi C., Bermejo-Climent J.R., Fabbian G., Legrand L., Paoletti D., Ballardini M., Archidiacono M., Douspis M., Finelli F., Ganga K., Hernandez-Monteagudo C., Lattanzi M., Marinucci D., Migliaccio M., Carbone C., Casas S., Martinelli M., Tutusaus I., Natoli P., Ntelis P., Pagano L., Wenzl L., Gruppuso A., Kitching T., Langer M., Mauri N., Patrizii L., Renzi A., Sirri G., Stanco L., Tenti M., Vielzeuf P., Lacasa F., Polenta G., Yankelevich V., Blanchard A., Sakr Z., Pourtsidou A., Camera S., Cardone V.F., Kilbinger M., Kunz M., Markovic K., Pettorino V., Sanchez A.G., Sapone D., Amara A., Auricchio N., Bender R., Bodendorf C., Bonino D., Branchini E., Brescia M., Brinchmann J., Capobianco V., Carretero J., Castander F.J., Castellano M., Cavuoti S., Cimatti A., Cledassou R., Congedo G., Conselice C.J., Conversi L., Copin Y., Corcione L., Costille A., Cropper M., Da Silva A., Degaudenzi H., Dubath F., Duncan C.A.J., Dupac X., Dusini S., Ealet A., Farrens S., Fosalba P., Frailis M., Franceschi E., Franzetti P., Fumana M., Garilli B., Gillard W., Gillis B., Giocoli C., Grazian A., Grupp F., Guzzo L., Haugan S.V.H., Hoekstra H., Holmes W., Hormuth F., Hudelot P., Jahnke K., Kermiche S., Kiessling A., Kohley R., Kubik B., Kummel M., Kurki-Suonio H., Laureijs R., Ligori S., Lilje P.B., Lloro I., Mansutti O., Marggraf O., Marulli F., Massey R., Maurogordato S., Meneghetti M., Merlin E., Meylan G., Moresco M., Morin B., Moscardini L., Munari E., Niemi S.M., Padilla C., Paltani S., Pasian F., Pedersen K., Percival W., Pires S., Poncet M., Popa L., Pozzetti L., Raison F., Rebolo R., Rhodes J., Roncarelli M., Rossetti E., Saglia R., Scaramella R., Schneider P., Secroun A., Seidel G., Serrano S., Sirignano C., Starck J.L., Tallada-Crespi P., Taylor A.N., Tereno I., Toledo-Moreo R., Torradeflot F., Valentijn E.A., Valenziano L., Verdoes Kleijn G.A., Wang Y., Welikala N., Weller J., Zamorani G., Zoubian J., Medinaceli E., Mei S., Rosset C., Sureau F., Vassallo T., Zacchei A., Andreon S., Balaguera-Antolinez A., Baldi M., Bardelli S., Biviano A., Borgani S., Bozzo E., Burigana C., Cabanac R., Cappi A., Carvalho C.S., Castignani G., Colodro-Conde C., Coupon J., Courtois H.M., Cuby J., De La Torre S., Di Ferdinando D., Dole H., Farina M., Ferreira P.G., Flose-Reimberg P., Galeotta S., Gozaliasl G., Gracia-Carpio J., Keihanen E., Kirkpatrick C.C., Lindholm V., Mainetti G., Maino D., Martinet N., Maturi M., Metcalf R.B., Morgante G., Neissner C., Nightingale J., Nucita A.A., Potter D., Riccio G., Romelli E., Schirmer M., Schultheis M., Scottez V., Teyssier R., Tramacere A., Valiviita J., Viel M., Whittaker L., Zucca E., Euclid, Collaboration, Ilić, S., Aghanim, N., Baccigalupi, C., Bermejo-Climent, J. R., Fabbian, G., Legrand, L., Paoletti, D., Ballardini, M., Archidiacono, M., Douspis, M., Finelli, F., Ganga, K., Hernández-Monteagudo, C., Lattanzi, M., Marinucci, D., Migliaccio, M., Carbone, C., Casas, S., Martinelli, M., Tutusaus, I., Natoli, P., Ntelis, P., Pagano, L., Wenzl, L., Gruppuso, A., Kitching, T., Langer, M., Mauri, N., Patrizii, L., Renzi, A., Sirri, G., Stanco, L., Tenti, M., Vielzeuf, P., Lacasa, F., Polenta, G., Yankelevich, V., Blanchard, A., Sakr, Z., Pourtsidou, A., Camera, S., Cardone, V. F., Kilbinger, M., Kunz, M., Markovic, K., Pettorino, V., Sánchez, A. G., Sapone, D., Amara, A., Auricchio, N., Bender, R., Bodendorf, C., Bonino, D., Branchini, E., Brescia, M., Brinchmann, J., Capobianco, V., Carretero, J., Castander, F. J., Castellano, M., Cavuoti, S., Cimatti, A., Cledassou, R., Congedo, G., Conselice, C. J., Conversi, L., Copin, Y., Corcione, L., Costille, A., Cropper, M., Da Silva, A., Degaudenzi, H., Dubath, F., Duncan, C. A. J., Dupac, X., Dusini, S., Ealet, A., Farrens, S., Fosalba, P., Frailis, M., Franceschi, E., Franzetti, P., Fumana, M., Garilli, B., Gillard, W., Gillis, B., Giocoli, C., Grazian, A., Grupp, F., Guzzo, L., Haugan, S. V. H., Hoekstra, H., Holmes, W., Hormuth, F., Hudelot, P., Jahnke, K., Kermiche, S., Kiessling, A., Kohley, R., Kubik, B., Kümmel, M., Kurki-Suonio, H., Laureijs, R., Ligori, S., Lilje, P. B., Lloro, I., Mansutti, O., Marggraf, O., Marulli, F., Massey, R., Maurogordato, S., Meneghetti, M., Merlin, E., Meylan, G., Moresco, M., Morin, B., Moscardini, L., Munari, E., Niemi, S. M., Padilla, C., Paltani, S., Pasian, F., Pedersen, K., Percival, W., Pires, S., Poncet, M., Popa, L., Pozzetti, L., Raison, F., Rebolo, R., Rhodes, J., Roncarelli, M., Rossetti, E., Saglia, R., Scaramella, R., Schneider, P., Secroun, A., Seidel, G., Serrano, S., Sirignano, C., Starck, J. L., Tallada-Crespí, P., Taylor, A. N., Tereno, I., Toledo-Moreo, R., Torradeflot, F., Valentijn, E. A., Valenziano, L., Verdoes Kleijn, G. A., Wang, Y., Welikala, N., Weller, J., Zamorani, G., Zoubian, J., Medinaceli, E., Mei, S., Rosset, C., Sureau, F., Vassallo, T., Zacchei, A., Andreon, S., Balaguera-Antolínez, A., Baldi, M., Bardelli, S., Biviano, A., Borgani, S., Bozzo, E., Burigana, C., Cabanac, R., Cappi, A., Carvalho, C. S., Castignani, G., Colodro-Conde, C., Coupon, J., Courtois, H. M., Cuby, J., de la Torre, S., Di Ferdinando, D., Dole, H., Farina, M., Ferreira, P. G., Flose-Reimberg, P., Galeotta, S., Gozaliasl, G., Graciá-Carpio, J., Keihanen, E., Kirkpatrick, C. C., Lindholm, V., Mainetti, G., Maino, D., Martinet, N., Maturi, M., Metcalf, R. B., Morgante, G., Neissner, C., Nightingale, J., Nucita, A. A., Potter, D., Riccio, G., Romelli, E., Schirmer, M., Schultheis, M., Scottez, V., Teyssier, R., Tramacere, A., Valiviita, J., Viel, M., Whittaker, L., Zucca, E., Department of Physics, Research Program in Systems Oncology, Helsinki Institute of Physics, Ilic, S., Hernandez-Monteagudo, C., Sanchez, A. G., Kummel, M., Tallada-Crespi, P., Balaguera-Antolinez, A., De La Torre, S., Gracia-Carpio, J., Ili??, S., Hern??ndez-Monteagudo, C., S??nchez, A. G., K??mmel, M., Tallada-Cresp??, P., Balaguera-Antol??nez, A., and Graci??-Carpio, J.
Subjects: Cosmology and Nongalactic Astrophysics (astro-ph.CO), Cosmic microwave background, statistical [methods], FOS: Physical sciences, Astrophysics, cosmic background radiation, Astrophysics::Cosmology and Extragalactic Astrophysics, Joint analysis, kosmologia, 01 natural sciences, methods, NO, pimeä aine, [PHYS.ASTR.CO]Physics [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO], mikroaallot, Settore FIS/05 - Astronomia e Astrofisica, surveys, 0103 physical sciences, tsz, survey, 010303 astronomy & astrophysics, Physics, methods: statistical, 010308 nuclear & particles physics, Computer Science::Information Retrieval, maailmankaikkeus, Astrophysics::Instrumentation and Methods for Astrophysics, Astronomy and Astrophysics, cross-correlation, 115 Astronomy, Space science, Cosmic background radiation, Large-scale structure of Universe, Methods: statistical, Surveys, kosminen taustasäteily, Space and Planetary Science, method, large-scale structure of Universe, pimeä energia, [PHYS.ASTR]Physics [physics]/Astrophysics [astro-ph], statistical, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: The combination and cross-correlation of the upcoming $Euclid$ data with cosmic microwave background (CMB) measurements is a source of great expectation since it will provide the largest lever arm of epochs, ranging from recombination to structure formation across the entire past light cone. In this work, we present forecasts for the joint analysis of $Euclid$ and CMB data on the cosmological parameters of the standard cosmological model and some of its extensions. This work expands and complements the recently published forecasts based on $Euclid$-specific probes, namely galaxy clustering, weak lensing, and their cross-correlation. With some assumptions on the specifications of current and future CMB experiments, the predicted constraints are obtained from both a standard Fisher formalism and a posterior-fitting approach based on actual CMB data. Compared to a $Euclid$-only analysis, the addition of CMB data leads to a substantial impact on constraints for all cosmological parameters of the standard $\Lambda$-cold-dark-matter model, with improvements reaching up to a factor of ten. For the parameters of extended models, which include a redshift-dependent dark energy equation of state, non-zero curvature, and a phenomenological modification of gravity, improvements can be of the order of two to three, reaching higher than ten in some cases. The results highlight the crucial importance for cosmological constraints of the combination and cross-correlation of $Euclid$ probes with CMB data., Comment: 20 pages, 8 figures, 5 tables, 1 appendix; updated to match version accepted by journal
Published: 2022
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38. Euclid preparation. XVI. Exploring the ultra-low surface brightness Universe with Euclid/VIS

Author: Euclid Collaboration, Borlaff, A. S., Gómez-Alvarez, P., Altieri, B., Marcum, P. M., Vavrek, R., Laureijs, R., Kohley, R., Buitrago, F., Cuillandre, J. -C., Duc, P. -A., Gaspar Venancio, L. M., Amara, A., Andreon, S., Auricchio, N., Azzollini, R., Baccigalupi, C., Balaguera-Antolínez, A., Baldi, M., Bardelli, S., Bender, R., Biviano, A., Bodendorf, C., Bonino, D., Bozzo, E., Branchini, E., Brescia, M., Brinchmann, J., Burigana, C., Cabanac, R., Camera, S., Candini, G. P., Capobianco, V., Cappi, A., Carbone, C., Carretero, J., Carvalho, C. S., Casas, S., Castander, F. J., Castellano, M., Castignani, G., Cavuoti, S., Cimatti, A., Cledassou, R., Colodro-Conde, C., Congedo, G., Conselice, C. J., Conversi, L., Copin, Y., Corcione, L., Coupon, J., Courtois, H. M., Cropper, M., Da Silva, A., Degaudenzi, H., Di Ferdinando, D., Douspis, M., Dubath, F., Duncan, C. A. J., Dupac, X., Dusini, S., Ealet, A., Fabricius, M., Farina, M., Farrens, S., Ferreira, P. G., Ferriol, S., Finelli, F., Flose-Reimberg, P., Fosalba, P., Frailis, M., Franceschi, E., Fumana, M., Galeotta, S., Ganga, K., Garilli, B., Gillis, B., Giocoli, C., Gozaliasl, G., Graciá-Carpio, J., Grazian, A., Grupp, F., Haugan, S. V. H., Holmes, W., Hormuth, F., Jahnke, K., Keihanen, E., Kermiche, S., Kiessling, A., Kilbinger, M., Kirkpatrick, C. C., Kitching, T., Knapen, J. H., Kubik, B., Kümmel, M., Kunz, M., Kurki-Suonio, H., Liebing, P., Ligori, S., Lilje, P. B., Lindholm, V., Lloro, I., Mainetti, G., Maino, D., Mansutti, O., Marggraf, O., Markovic, K., Martinelli, M., Martinet, N., Martínez-Delgado, D., Marulli, F., Massey, R., Maturi, M., Maurogordato, S., Medinaceli, E., Mei, S., Meneghetti, M., Merlin, E., Metcalf, R. B., Meylan, G., Moresco, M., Morgante, G., Moscardini, L., Munari, E., Nakajima, R., Neissner, C., Niemi, S. M., Nightingale, J. W., Nucita, A., Padilla, C., Paltani, S., Pasian, F., Patrizii, L., Pedersen, K., Percival, W. J., Pettorino, V., Pires, S., Poncet, M., Popa, L., Potter, D., Pozzetti, L., Raison, F., Rebolo, R., Renzi, A., Rhodes, J., Riccio, G., Romelli, E., Roncarelli, M., Rosset, C., Rossetti, E., Saglia, R., Sánchez, A. G., Sapone, D., Sauvage, M., Schneider, P., Scottez, V., Secroun, A., Seidel, G., Serrano, S., Sirignano, C., Sirri, G., Skottfelt, J., Stanco, L., Starck, J. L., Sureau, F., Tallada-Crespí, P., Taylor, A. N., Tenti, M., Tereno, I., Teyssier, R., Toledo-Moreo, R., Torradeflot, F., Tutusaus, I., Valentijn, E. A., Valenziano, L., Valiviita, J., Vassallo, T., Viel, M., Wang, Y., Weller, J., Whittaker, L., Zacchei, A., Zamorani, G., Zucca, E., Euclid, Collaboration, Borlaff, A. S., Gómez-Alvarez, P., Altieri, B., Marcum, P. M., Vavrek, R., Laureijs, R., Kohley, R., Buitrago, F., Cuillandre, J. -C., Duc, P. -A., Gaspar Venancio, L. M., Amara, A., Andreon, S., Auricchio, N., Azzollini, R., Baccigalupi, C., Balaguera-Antolínez, A., Baldi, M., Bardelli, S., Bender, R., Biviano, A., Bodendorf, C., Bonino, D., Bozzo, E., Branchini, E., Brescia, M., Brinchmann, J., Burigana, C., Cabanac, R., Camera, S., Candini, G. P., Capobianco, V., Cappi, A., Carbone, C., Carretero, J., Carvalho, C. S., Casas, S., Castander, F. J., Castellano, M., Castignani, G., Cavuoti, S., Cimatti, A., Cledassou, R., Colodro-Conde, C., Congedo, G., Conselice, C. J., Conversi, L., Copin, Y., Corcione, L., Coupon, J., Courtois, H. M., Cropper, M., Da Silva, A., Degaudenzi, H., Di Ferdinando, D., Douspis, M., Dubath, F., Duncan, C. A. J., Dupac, X., Dusini, S., Ealet, A., Fabricius, M., Farina, M., Farrens, S., Ferreira, P. G., Ferriol, S., Finelli, F., Flose-Reimberg, P., Fosalba, P., Frailis, M., Franceschi, E., Fumana, M., Galeotta, S., Ganga, K., Garilli, B., Gillis, B., Giocoli, C., Gozaliasl, G., Graciá-Carpio, J., Grazian, A., Grupp, F., Haugan, S. V. H., Holmes, W., Hormuth, F., Jahnke, K., Keihanen, E., Kermiche, S., Kiessling, A., Kilbinger, M., Kirkpatrick, C. C., Kitching, T., Knapen, J. H., Kubik, B., Kümmel, M., Kunz, M., Kurki-Suonio, H., Liebing, P., Ligori, S., Lilje, P. B., Lindholm, V., Lloro, I., Mainetti, G., Maino, D., Mansutti, O., Marggraf, O., Markovic, K., Martinelli, M., Martinet, N., Martínez-Delgado, D., Marulli, F., Massey, R., Maturi, M., Maurogordato, S., Medinaceli, E., Mei, S., Meneghetti, M., Merlin, E., Metcalf, R. B., Meylan, G., Moresco, M., Morgante, G., Moscardini, L., Munari, E., Nakajima, R., Neissner, C., Niemi, S. M., Nightingale, J. W., Nucita, A., Padilla, C., Paltani, S., Pasian, F., Patrizii, L., Pedersen, K., Percival, W. J., Pettorino, V., Pires, S., Poncet, M., Popa, L., Potter, D., Pozzetti, L., Raison, F., Rebolo, R., Renzi, A., Rhodes, J., Riccio, G., Romelli, E., Roncarelli, M., Rosset, C., Rossetti, E., Saglia, R., Sánchez, A. G., Sapone, D., Sauvage, M., Schneider, P., Scottez, V., Secroun, A., Seidel, G., Serrano, S., Sirignano, C., Sirri, G., Skottfelt, J., Stanco, L., Starck, J. L., Sureau, F., Tallada-Crespí, P., Taylor, A. N., Tenti, M., Tereno, I., Teyssier, R., Toledo-Moreo, R., Torradeflot, F., Tutusaus, I., Valentijn, E. A., Valenziano, L., Valiviita, J., Vassallo, T., Viel, M., Wang, Y., Weller, J., Whittaker, L., Zacchei, A., Zamorani, G., Zucca, E., European Commission, Ministerio de Ciencia e Innovación (España), Borlaff A.S., Gomez-Alvarez P., Altieri B., Marcum P.M., Vavrek R., Laureijs R., Kohley R., Buitrago F., Cuillandre J.-C., Duc P.-A., Gaspar Venancio L.M., Amara A., Andreon S., Auricchio N., Azzollini R., Baccigalupi C., Balaguera-Antolinez A., Baldi M., Bardelli S., Bender R., Biviano A., Bodendorf C., Bonino D., Bozzo E., Branchini E., Brescia M., Brinchmann J., Burigana C., Cabanac R., Camera S., Candini G.P., Capobianco V., Cappi A., Carbone C., Carretero J., Carvalho C.S., Casas S., Castander F.J., Castellano M., Castignani G., Cavuoti S., Cimatti A., Cledassou R., Colodro-Conde C., Congedo G., Conselice C.J., Conversi L., Copin Y., Corcione L., Coupon J., Courtois H.M., Cropper M., Da Silva A., Degaudenzi H., Di Ferdinando D., Douspis M., Dubath F., Duncan C.A.J., Dupac X., Dusini S., Ealet A., Fabricius M., Farina M., Farrens S., Ferreira P.G., Ferriol S., Finelli F., Flose-Reimberg P., Fosalba P., Frailis M., Franceschi E., Fumana M., Galeotta S., Ganga K., Garilli B., Gillis B., Giocoli C., Gozaliasl G., Gracia-Carpio J., Grazian A., Grupp F., Haugan S.V.H., Holmes W., Hormuth F., Jahnke K., Keihanen E., Kermiche S., Kiessling A., Kilbinger M., Kirkpatrick C.C., Kitching T., Knapen J.H., Kubik B., Kummel M., Kunz M., Kurki-Suonio H., Liebing P., Ligori S., Lilje P.B., Lindholm V., Lloro I., Mainetti G., Maino D., Mansutti O., Marggraf O., Markovic K., Martinelli M., Martinet N., Martinez-Delgado D., Marulli F., Massey R., Maturi M., Maurogordato S., Medinaceli E., Mei S., Meneghetti M., Merlin E., Metcalf R.B., Meylan G., Moresco M., Morgante G., Moscardini L., Munari E., Nakajima R., Neissner C., Niemi S.M., Nightingale J.W., Nucita A., Padilla C., Paltani S., Pasian F., Patrizii L., Pedersen K., Percival W.J., Pettorino V., Pires S., Poncet M., Popa L., Potter D., Pozzetti L., Raison F., Rebolo R., Renzi A., Rhodes J., Riccio G., Romelli E., Roncarelli M., Rosset C., Rossetti E., Saglia R., Sanchez A.G., Sapone D., Sauvage M., Schneider P., Scottez V., Secroun A., Seidel G., Serrano S., Sirignano C., Sirri G., Skottfelt J., Stanco L., Starck J.L., Sureau F., Tallada-Crespi P., Taylor A.N., Tenti M., Tereno I., Teyssier R., Toledo-Moreo R., Torradeflot F., Tutusaus I., Valentijn E.A., Valenziano L., Valiviita J., Vassallo T., Viel M., Wang Y., Weller J., Whittaker L., Zacchei A., Zamorani G., Zucca E., Joseph Louis LAGRANGE (LAGRANGE), Université Côte d'Azur (UCA)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Gomez-Alvarez, P., Balaguera-Antolinez, A., Gracia-Carpio, J., Kummel, M., Martinez-Delgado, D., Sanchez, A. G., Tallada-Crespi, P., Observatoire astronomique de Strasbourg (ObAS), Université de Strasbourg (UNISTRA)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Astrophysique de Marseille (LAM), Aix Marseille Université (AMU)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS), Astronomy, Astrophysique Interprétation Modélisation (AIM (UMR7158 / UMR_E_9005 / UM_112)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Institut de recherche en astrophysique et planétologie (IRAP), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire Midi-Pyrénées (OMP), Institut de Recherche pour le Développement (IRD)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Institut de Recherche pour le Développement (IRD)-Institut national des sciences de l'Univers (INSU - CNRS)-Centre National d'Études Spatiales [Toulouse] (CNES)-Centre National de la Recherche Scientifique (CNRS)-Météo-France -Centre National de la Recherche Scientifique (CNRS), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Centre National d'Études Spatiales [Toulouse] (CNES), Institut de Physique des 2 Infinis de Lyon (IP2I Lyon), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Institut d'astrophysique spatiale (IAS), Institut national des sciences de l'Univers (INSU - CNRS)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Centre National d’Études Spatiales [Paris] (CNES), Institut d'Astrophysique de Paris (IAP), Institut national des sciences de l'Univers (INSU - CNRS)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Centre de Calcul de l'IN2P3 (CC-IN2P3), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut national des sciences de l'Univers (INSU - CNRS)-Observatoire de la Côte d'Azur, COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Université Côte d'Azur (UCA)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Department of Physics, Research Program in Systems Oncology, and Helsinki Institute of Physics
Subjects: diffuse light, stellar haloes, FOS: Physical sciences, Galaxies: general, Instrumentation: detectors, Methods: observational, Space vehicles: instruments, Techniques: image processing, Techniques: photometric, virgo cluster, techniques: image processing, Astrophysics::Cosmology and Extragalactic Astrophysics, Space vehicles: instrument, 01 natural sciences, 7. Clean energy, instruments [Space vehicles], techniques: photometric, Settore FIS/05 - Astronomia e Astrofisica, 0103 physical sciences, spiral galaxies, image processing [Techniques], observational [Methods], space vehicles: instruments, Instrumentation and Methods for Astrophysics (astro-ph.IM), 010303 astronomy & astrophysics, detectors [Instrumentation], Astrophysics::Galaxy Astrophysics, data release, Instrumentation: detector, substructure, 010308 nuclear & particles physics, instrumentation: detectors, photometric [Techniques], Astrophysics::Instrumentation and Methods for Astrophysics, Astronomy and Astrophysics, general [Galaxies], 115 Astronomy, Space science, calibration, Astrophysics - Astrophysics of Galaxies, galaxies: general, Space and Planetary Science, [SDU]Sciences of the Universe [physics], Astrophysics of Galaxies (astro-ph.GA), deep, methods: observational, Astrophysics - Instrumentation and Methods for Astrophysics, tidal features, tracing galaxy formation
Abstract: Full list of authors: Borlaff, A. S.; Gómez-Alvarez, P.; Altieri, B.; Marcum, P. M.; Vavrek, R.; Laureijs, R.; Kohley, R.; Buitrago, F.; Cuillandre, J. -C.; Duc, P. -A.; Gaspar Venancio, L. M.; Amara, A.; Andreon, S.; Auricchio, N.; Azzollini, R.; Baccigalupi, C.; Balaguera-Antolínez, A.; Baldi, M.; Bardelli, S.; Bender, R.; Biviano, A.; Bodendorf, C.; Bonino, D.; Bozzo, E.; Branchini, E.; Brescia, M.; Brinchmann, J.; Burigana, C.; Cabanac, R.; Camera, S.; Candini, G. P.; Capobianco, V.; Cappi, A.; Carbone, C.; Carretero, J.; Carvalho, C. S.; Casas, S.; Castander, F. J.; Castellano, M.; Castignani, G.; Cavuoti, S.; Cimatti, A.; Cledassou, R.; Colodro-Conde, C.; Congedo, G.; Conselice, C. J.; Conversi, L.; Copin, Y.; Corcione, L.; Coupon, J.; Courtois, H. M.; Cropper, M.; Da Silva, A.; Degaudenzi, H.; Di Ferdinando, D.; Douspis, M.; Dubath, F.; Duncan, C. A. J.; Dupac, X.; Dusini, S.; Ealet, A.; Fabricius, M.; Farina, M. ; Farrens, S.; Ferreira, P. G.; Ferriol, S.; Finelli, F.; Flose-Reimberg, P.; Fosalba, P.; Frailis, M.; Franceschi, E.; Fumana, M.; Galeotta, S.; Ganga, K.; Garilli, B.; Gillis, B.; Giocoli, C.; Gozaliasl, G.; Graciá-Carpio, J.; Grazian, A.; Grupp, F.; Haugan, S. V. H.; Holmes, W.; Hormuth, F.; Jahnke, K.; Keihanen, E.; Kermiche, S.; Kiessling, A.; Kilbinger, M.; Kirkpatrick, C. C.; Kitching, T.; Knapen, J. H.; Kubik, B.; Kümmel, M.; Kunz, M.; Kurki-Suonio, H.; Liebing, P.; Ligori, S.; Lilje, P. B.; Lindholm, V.; Lloro, I.; Mainetti, G.; Maino, D.; Mansutti, O.; Marggraf, O.; Markovic, K.; Martinelli, M.; Martinet, N.; Martínez-Delgado, D.; Marulli, F.; Massey, R.; Maturi, M.; Maurogordato, S.; Medinaceli, E.; Mei, S.; Meneghetti, M.; Merlin, E.; Metcalf, R. B.; Meylan, G.; Moresco, M.; Morgante, G.; Moscardini, L.; Munari, E.; Nakajima, R.; Neissner, C.; Niemi, S. M.; Nightingale, J. W.; Nucita, A.; Padilla, C.; Paltani, S.; Pasian, F.; Patrizii, L.; Pedersen, K.; Percival, W. J.; Pettorino, V.; Pires, S.; Poncet, M.; Popa, L.; Potter, D.; Pozzetti, L.; Raison, F.; Rebolo, R.; Renzi, A.; Rhodes, J.; Riccio, G.; Romelli, E.; Roncarelli, M.; Rosset, C.; Rossetti, E.; Saglia, R.; Sánchez, A. G.; Sapone, D.; Sauvage, M.; Schneider, P.; Scottez, V.; Secroun, A.; Seidel, G.; Serrano, S.; Sirignano, C.; Sirri, G.; Skottfelt, J.; Stanco, L.; Starck, J. L.; Sureau, F.; Tallada-Crespí, P.; Taylor, A. N.; Tenti, M.; Tereno, I.; Teyssier, R.; Toledo-Moreo, R.; Torradeflot, F.; Tutusaus, I.; Valentijn, E. A.; Valenziano, L.; Valiviita, J.; Vassallo, T.; Viel, M.; Wang, Y.; Weller, J.; Whittaker, L.; Zacchei, A.; Zamorani, G.; Zucca, E.; Euclid Collaboration., Context. While Euclid is an ESA mission specifically designed to investigate the nature of dark energy and dark matter, the planned unprecedented combination of survey area (∼15 000 deg2), spatial resolution, low sky-background, and depth also make Euclid an excellent space observatory for the study of the low surface brightness Universe. Scientific exploitation of the extended low surface brightness structures requires dedicated calibration procedures that are yet to be tested. Aims. We investigate the capabilities of Euclid to detect extended low surface brightness structure by identifying and quantifying sky-background sources and stray-light contamination. We test the feasibility of generating sky flat-fields to reduce large-scale residual gradients in order to reveal the extended emission of galaxies observed in the Euclid survey. Methods. We simulated a realistic set of Euclid/VIS observations, taking into account both instrumental and astronomical sources of contamination, including cosmic rays, stray-light, zodiacal light, interstellar medium, and the cosmic infrared background, while simulating the effects of background sources in the field of view. Results. We demonstrate that a combination of calibration lamps, sky flats, and self-calibration would enable recovery of emission at a limiting surface brightness magnitude of μlim = 29.5−0.27+0.08 mag arcsec−2 (3σ, 10 × 10 arcsec2) in the Wide Survey, and it would reach regions deeper by 2 mag in the Deep Surveys. Conclusions.Euclid/VIS has the potential to be an excellent low surface brightness observatory. Covering the gap between pixel-to-pixel calibration lamp flats and self-calibration observations for large scales, the application of sky flat-fielding will enhance the sensitivity of the VIS detector at scales larger than 1″, up to the size of the field of view, enabling Euclid to detect extended surface brightness structures below μlim = 31 mag arcsec−2 and beyond. © ESO 2022., A. B. was supported by an appointment to the NASA Postdoctoral Program at the NASA Ames Research Center, administered by Universities Space Research Association under contract with NASA, and the European Space Agency (ESA), through the European Space Astronomy Center Faculty. We acknowledge a number of agencies and institutes that have supported the development of Euclid, in particular the Academy of Finland, the Agenzia Spaziale Italiana, the Belgian Science Policy, the Canadian Euclid Consortium, the Centre National d’Etudes Spatiales, the Deutsches Zentrum für Luft- und Raumfahrt, the Danish Space Research Institute, the Fundação para a Ciência e a Tecnologia, the Ministerio de Economia y Competitividad, the National Aeronautics and Space Administration, the National Astronomical Observatory of Japan, the Netherlandse Onderzoekschool Voor Astronomie, the Norwegian Space Agency, the Romanian Space Agency, the State Secretariat for Education, Research and Innovation (SERI) at the Swiss Space Office (SSO), and the United Kingdom Space Agency. A complete and detailed list is available on the Euclid website (http://www.euclid-ec.org). This work has made use of data from the ESA mission Gaia (https://www.cosmos.esa.int/gaia), processed by the Gaia Data Processing and Analysis Consortium (DPAC, https://www.cosmos.esa.int/web/gaia/dpac/consortium). Funding for the DPAC has been provided by national institutions, in particular the institutions participating in the Gaia Multilateral Agreement. This research made use of NumPy (Van Der Walt et al. 2011), Astropy, a community-developed core Python package for Astronomy (Astropy Collaboration 2013). All of the figures on this publication were generated using Matplotlib (Hunter 2007). This work was partly done using GNU Astronomy Utilities (Gnuastro, ascl.net/1801.009) version 0.11.22-dc86., With funding from the Spanish government through the Severo Ochoa Centre of Excellence accreditation SEV-2017-0709.
Published: 2022
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39. Sensitivity projections for a dual-phase argon TPC optimized for light dark matter searches through the ionization channel

Author: Agnes, P., Ahmad, I., Albergo, S., Albuquerque, I.F.M., Alexander, T., Alton, A.K., Amaudruz, P., Atzori Corona, M., Auty, D.J., Ave, M., Avetisov, I.Ch., Avetisov, R.I., Azzolini, O., Back, H.O., Balmforth, Z., Barbarian, V., Barrado Olmedo, A., Barrillon, P., Basco, A., Batignani, G., Berzin, E., Bondar, A., Bonivento, W.M., Borisova, E., Bottino, B., Boulay, M.G., Buccino, G., Bussino, S., Busto, J., Buzulutskov, A., Cadeddu, M., Cadoni, M., Caminata, A., Canci, N., Capra, A., Caprioli, S., Caravati, M., Cárdenas-Montes, M., Cargioli, N., Carlini, M., Castello, P., Cataudella, V., Cavalcante, P., Cavuoti, S., Cebrian, S., Cela Ruiz, J.M., Chashin, S., Chepurnov, A., Chyhyrynets, E., Cicalò, C., Cifarelli, L., Cintas, D., Cocco, V., Conde Vilda, E., Consiglio, L., Copello, S., Covone, G., Cross, S., Czubak, M., Czudak, P., D'Aniello, M., D'Auria, S., Da Rocha Rolo, M.D., Dadoun, O., Daniel, M., Davini, S., De Candia, A., De Cecco, S., De Falco, A., De Filippis, G., De Gruttola, D., De Pasquale, S., De Rosa, G., Dellacasa, G., Derbin, A.V., Devoto, A., Di Capua, F., Di Noto, L., Di Stefano, P., Dionisi, C., Dolganov, G., Dordei, F., Doria, L., Erjavec, T., Fernandez Diaz, M., Fiorillo, G., Franceschi, A., Franchini, P., Franco, D., Frolov, E., Funicello, N., Gabriele, F., Gahan, D., Galbiati, C., Gallina, G., Gallus, G., Garbini, M., Garcia Abia, P., Gendotti, A., Ghiano, C., Giampaolo, R.A., Giganti, C., Giorgi, M.A., Giovanetti, G.K., Goicoechea Casanueva, V., Gola, A., Gorman, D., Graciani Diaz, R., Grauso, G., Grilli di Cortona, G., Grobov, A., Gromov, M., Guan, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B.R., Hall, J.B., Hallin, A.L., Hamer, A., Helton, H., Haranczyk, M., Hessel, T., Hill, S., Horikawa, S., Hubaut, F., Hugues, T., Hungerford, E.V., Ianni, An., Ippolito, V., Jillings, C., Kachru, P., Kemp, A.A., Kendziora, C.L., Keppel, G., Khomyakov, A.V., Kimura, M., Kochanek, I., Kondo, K., Korga, G., Koulosousas, S., Kubankin, A., Kuss, M., Kuźniak, M., La Commara, M., Lai, M., Le Guirriec, E., Leason, E., Li, X., Lidey, L., Lipp, J., Lissia, M., Longo, G., Luzzi, L., Macfadyen, O., Machulin, I.N., Manthos, I., Mapelli, L., Margotti, A., Mari, S.M., Mariani, C., Maricic, J., Marini, A., Martínez, M., Martoff, C.J., Masoni, A., Mavrokoridis, K., Mazzi, A., McDonald, A.B., Messina, A., Milincic, R., Moggi, A., Moharana, A., Monroe, J., Morrocchi, M., Mozhevitina, E.N., Mróz, T., Muratova, V.N., Muscas, C., Musico, P., Nania, R., Napolitano, T., Nessi, M., Nieradka, G., Nikolopoulos, K., Nikulin, I., Nowak, J., Olchansky, K., Oleinik, A., Oleynikov, V., Organtini, P., Ortiz de Solórzano, A., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Paternoster, G., Pegoraro, P.A., Pelczar, K., Pellegrino, C., Perotti, F., Pesudo, V., Piacentini, S., Pietropaolo, F., Pino, N., Pira, C., Pocar, A., Poehlmann, D.M., Pordes, S., Pralavorio, P., Price, D., Raffaelli, F., Ragusa, F., Ramachers, Y., Ramirez, A., Razeti, M., Razeto, A., Renshaw, A.L., Rescigno, M., Resnati, F., Retiere, F., Rignanese, L.P., Ripoli, C., Rivetti, A., Roberts, A., Roberts, C., Rode, J., Rogers, G., Romero, L., Rossi, M., Rubbia, A., Sadashivajois, S., Saffold, T.R., Samoylov, O., Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Savarese, C., Scapparone, E., Scioli, G., Semenov, D.A., Shchagin, A., Sheshukov, A., Simeone, M., Skensved, P., Skorokhvatov, M.D., Smirnov, O., Smirnova, T., Smith, B., Sokolov, A., Spangenberg, M., Stefanizzi, R., Steri, A., Stracka, S., Strickland, V., Stringer, M., Sulis, S., Sung, A., Suvorov, Y., Szelc, A.M., Türkoğ, C., Türkoğlu, C., Tartaglia, R., Taylor, A., Taylor, J., Tedesco, S., Testera, G., Thieme, K., Thorpe, T.N., Tonazzo, A., Torres-Lara, S., Tricomi, A., Unzhakov, E.V., Vallivilayil John, T., Van Uffelen, M., Viant, T., Viel, S., Vishneva, A., Vogelaar, R.B., Vossebeld, J., Wada, M., Walczak, M.B., Wang, Y., Westerdale, S., Wheadon, R.J., Williams, L., Wingerter-Seez, I., Wojaczyński, R., Wojcik, Ma.M., Wojcik, Ma., Wright, T., Xie, Y., Yang, C., Zabihi, A., Zakhary, P., Zani, A., Zichichi, A., Zuzel, G., Zykova, M.P., Centre de Physique des Particules de Marseille (CPPM), Aix Marseille Université (AMU)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physique Nucléaire et de Hautes Énergies (LPNHE (UMR_7585)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), AstroParticule et Cosmologie (APC (UMR_7164)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Global Argon Dark Matter, Agnes, P., Ahmad, I., Albergo, S., Albuquerque, I. F. M., Alexander, T., Alton, A. K., Amaudruz, P., Atzori Corona, M., Auty, D. J., Ave, M., Avetisov, I. Ch., Avetisov, R. I., Azzolini, O., Back, H. O., Balmforth, Z., Barbarian, V., Barrado Olmedo, A., Barrillon, P., Basco, A., Batignani, G., Berzin, E., Bondar, A., Bonivento, W. M., Borisova, E., Bottino, B., Boulay, M. G., Buccino, G., Bussino, S., Busto, J., Buzulutskov, A., Cadeddu, M., Cadoni, M., Caminata, A., Canci, N., Capra, A., Caprioli, S., Caravati, M., Cardenas-Montes, M., Cargioli, N., Carlini, M., Castello, P., Cataudella, V., Cavalcante, P., Cavuoti, S., Cebrian, S., Cela Ruiz, J. M., Chashin, S., Chepurnov, A., Chyhyrynets, E., Cicalò, C., Cifarelli, L., Cintas, D., Cocco, V., Conde Vilda, E., Consiglio, L., Copello, S., Covone, G., Cross, S., Czubak, M., D'Aniello, M., D'Auria, S., Da Rocha Rolo, M. D., Dadoun, O., Daniel, M., Davini, S., De Candia, A., De Cecco, S., De Falco, A., De Filippis, G., De Gruttola, D., De Pasquale, S., De Rosa, G., Dellacasa, G., Derbin, A. V., Devoto, A., Di Capua, F., Di Noto, L., Di Stefano, P., Dionisi, C., Dolganov, G., Dordei, F., Doria, L., Erjavec, T., Fernandez Diaz, M., Fiorillo, G., Franceschi, A., Franchini, P., Franco, D., Frolov, E., Funicello, N., Gabriele, F., Gahan, D., Galbiati, C., Gallina, G., Gallus, G., Garbini, M., Garcia Abia, P., Gendotti, A., Ghiano, C., Giampaolo, R. A., Giganti, C., Giorgi, M. A., Giovanetti, G. K., Goicoechea Casanueva, V., Gola, A., Gorman, D., Graciani Diaz, R., Grauso, G., Grilli di Cortona, G., Grobov, A., Gromov, M., Guan, M., Guerzoni, M., Gulino, M., Guo, C., Hackett, B. R., Hall, J. B., Hallin, A. L., Hamer, A., Helton, H., Haranczyk, M., Hessel, T., Hill, S., Horikawa, S., Hubaut, F., Hugues, T., Hungerford, E. V., Ianni, An., Ippolito, V., Jillings, C., Kachru, P., Kemp, A. A., Kendziora, C. L., Keppel, G., Khomyakov, A. V., Kimura, M., Kochanek, I., Kondo, K., Korga, G., Koulosousas, S., Kubankin, A., Kuss, M., Kuzniak, M., La Commara, M., Lai, M., Le Guirriec, E., Leason, E., Li, X., Lidey, L., Lipp, J., Lissia, M., Longo, G., Luzzi, L., Macfadyen, O., Machulin, I. N., Manthos, I., Mapelli, L., Margotti, A., Mari, S. M., Mariani, C., Maricic, J., Marini, A., Martinez, M., Martoff, C. J., Masoni, A., Mavrokoridis, K., Mazzi, A., Mcdonald, A. B., Messina, A., Milincic, R., Moggi, A., Moharana, A., Monroe, J., Morrocchi, M., Mozhevitina, E. ???N., Mroz, T., Muratova, V. N., Muscas, C., Musico, P., Nania, R., Napolitano, T., Nessi, M., Nieradka, G., Nikolopoulos, K., Nikulin, I., Nowak, J., Olchansky, K., Oleinik, A., Oleynikov, V., Organtini, P., Ortiz de Solorzano, A., Pagani, L., Pallavicini, M., Pandola, L., Pantic, E., Paoloni, E., Paternoster, G., Pegoraro, P. A., Pelczar, K., Pellegrino, C., Perotti, F., Pesudo, V., Piacentini, S., Pietropaolo, F., Pino, N., Pira, C., Pocar, A., Poehlmann, D. M., Pordes, S., Pralavorio, P., Price, D., Raffaelli, F., Ragusa, F., Ramachers, Y., Ramirez, A., Razeti, M., Razeto, A., Renshaw, A. L., Rescigno, M., Resnati, F., Retiere, F., Rignanese, L. P., Ripoli, C., Rivetti, A., Roberts, A., Roberts, C., Rode, J., Rogers, G., Romero, L., Rossi, M., Rubbia, A., Sadashivajois, S., Saffold, T. R., Samoylov, O., Sandford, E., Sanfilippo, S., Santone, D., Santorelli, R., Savarese, C., Scapparone, E., Scioli, G., Semenov, D. A., Shchagin, A., Sheshukov, A., Simeone, M., Skensved, P., Skorokhvatov, M. D., Smirnov, O., Smirnova, T., Smith, B., Sokolov, A., Spangenberg, M., Stefanizzi, R., Steri, A., Stracka, S., Strickland, V., Stringer, M., Sulis, S., Sung, A., Suvorov, Y., Szelc, A. M., Türkoglu, C., Tartaglia, R., Taylor, A., Taylor, J., Tedesco, S., Testera, G., Thieme, K., Thorpe, T. N., Tonazzo, A., Torres-Lara, S., Tricomi, A., Unzhakov, E. V., Vallivilayil John, T., Van Uffelen, M., Viant, T., Viel, S., Vishneva, A., Vogelaar, R. B., Vossebeld, J., Wada, M., Walczak, M. B., Wang, Y., Westerdale, S., Wheadon, R. J., Williams, L., Wingerter-Seez, I., Wojaczynski, R., Wojcik, Ma. M., Wojcik, Ma., Wright, T., Xie, Y., Yang, C., Zabihi, A., Zakhary, P., Zani, A., Zichichi, A., Zuzel, G., and Zykova, M. P.
Subjects: Physics - Instrumentation and Detectors, hep-ex, FOS: Physical sciences, Instrumentation and Detectors (physics.ins-det), dark matter: detector, sensitivity, High Energy Physics - Experiment, time projection chamber, High Energy Physics - Experiment (hep-ex), electron: background, argon, [PHYS.HEXP]Physics [physics]/High Energy Physics - Experiment [hep-ex], [PHYS.PHYS.PHYS-INS-DET]Physics [physics]/Physics [physics]/Instrumentation and Detectors [physics.ins-det], Detectors and Experimental Techniques, physics.ins-det, activity report, detector: design, Particle Physics - Experiment
Abstract: Dark matter lighter than 10 GeV/c2 encompasses a promising range of candidates. A conceptual design for a new detector, DarkSide-LowMass, is presented, based on the DarkSide-50 detector and progress toward DarkSide-20k, optimized for a low-threshold electron-counting measurement. Sensitivity to light dark matter is explored for various potential energy thresholds and background rates. These studies show that DarkSide-LowMass can achieve sensitivity to light dark matter down to the solar neutrino fog for GeV-scale masses and significant sensitivity down to 10 MeV/c2 considering the Migdal effect or interactions with electrons. Requirements for optimizing the detector’s sensitivity are explored, as are potential sensitivity gains from modeling and mitigating spurious electron backgrounds that may dominate the signal at the lowest energies. Dark matter lighter than 10 GeV/c$^2$ encompasses a promising range of candidates. A conceptual design for a new detector, DarkSide-LowMass, is presented, based on the DarkSide-50 detector and progress toward DarkSide-20k, optimized for a low-threshold electron-counting measurement. Sensitivity to light dark matter is explored for various potential energy thresholds and background rates. These studies show that DarkSide-LowMass can achieve sensitivity to light dark matter down to the solar neutrino floor for GeV-scale masses and significant sensitivity down to 10 MeV/c$^2$ considering the Migdal effect or interactions with electrons. Requirements for optimizing the detector's sensitivity are explored, as are potential sensitivity gains from modeling and mitigating spurious electron backgrounds that may dominate the signal at the lowest energies.
Published: 2022
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40. Limits on non-canonical heating and turbulence in the intergalactic medium from the low redshift Lyman α forest

Author: James S Bolton, Prakash Gaikwad, Martin G Haehnelt, Tae-Sun Kim, Fahad Nasir, Ewald Puchwein, Matteo Viel, and Bart P Wakker
Subjects: Cosmology and Nongalactic Astrophysics (astro-ph.CO), Space and Planetary Science, Astrophysics of Galaxies (astro-ph.GA), FOS: Physical sciences, Astronomy and Astrophysics, Astrophysics - Astrophysics of Galaxies, Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract: We examine the column density distribution function (CDDF) and Doppler parameter distribution from hydrodynamical simulations and Cosmic Origins Spectrograph (COS) observations of the Lyman-alpha forest at redshift $0\leq z\leq 0.2$. Allowing for a factor of two uncertainty in the metagalactic HI photoionisation rate, our hydrodynamical simulations are in good agreement ($1$-$1.5\sigma$) with the shape and amplitude of the observed CDDF at HI column densities $10^{13.3}\rm\,cm^{-2}\leq N_{\rm HI}\leq 10^{14.5}\rm\,cm^{-2}$. However, the Doppler widths of the simulated lines remain too narrow with respect to the COS data. We argue that invoking AGN feedback does not resolve this discrepancy. We also disfavour enhanced photoheating rates as a potential solution, as this requires an unphysically hard UV background spectrum. If instead appealing to a non-canonical source of heating, an additional specific heat injection of $u \lesssim 6.9\rm\,eV\,m_{\rm p}^{-1}$ is required at $z\lesssim 2.5$ for gas that has $N_{\rm HI}\simeq 10^{13.5}\rm\,cm^{-2}$ by $z=0.1$. Alternatively, there may be an unresolved line of sight turbulent velocity component of $v_{\rm turb}\lesssim 8.5\rm\,km\,s^{-1}(N_{\rm HI}/10^{13.5}\rm\,cm^{-2})^{0.21}$ for the coldest gas in the diffuse IGM., Comment: 21 pages, 13 figures, MNRAS accepted following revision. The accepted version includes an extra panel in figure 2 and some additional clarifications on the line broadening within the models. Conclusions unchanged
Published: 2022
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41. Entrapment within an ottoman storage bed: an unusual accidental asphyxial death

Author: Alessandro Cinquetti, Giorgia Franchetti, Giulia Fichera, Chiara Giraudo, Guido Viel, and Giovanni Cecchetto
Subjects: Forensic histology, Postural asphyxia, Pulmonary Edema, Beds, General Medicine, Mechanical asphyxia, Forensic Medicine, Forensic pathology, Pathology and Forensic Medicine, Asphyxia, Accidental death, Autopsy, Humans
Abstract: Herein, we present an uncommon forensic case of death by asphyxia. The victim was a woman whose body at death scene investigation (DSI) was discovered beside an ottoman storage bed. According to the rescue team, who had moved the body before our arrival, the body was originally found in the prone position and stuck with the neck, thorax and arms within the bed. Examination of the body showed hypostasis that was mainly distributed to the face and the lower chest while sparing the neck and the upper chest. The face was markedly swollen, and the eyes were congested with blood. Dissection and histology revealed pulmonary oedema and emphysema of both lungs. Integrating circumstantial, radiology and autopsy data, it was established that the victim, while trapped between the mattress and the edge of the ottoman storage bed, died by mechanical asphyxia due to cervical-thoracic compression and postural asphyxia acting simultaneously.
Published: 2022
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42. Cardiotoxicity from Capecitabine Chemotherapy: Prospective Study of Incidence at Rest and During Physical Exercise

Author: Chiara Lestuzzi, Davide Stolfo, Antonino De Paoli, Alberto Banzato, Angela Buonadonna, Ettore Bidoli, Lucia Tartuferi, Elda Viel, Giulia De Angelis, Sara Lonardi, Roberto Innocente, Massimiliano Berretta, Francesca Bergamo, Alessandra Guglielmi, Gianfranco Sinagra, and Joerg Herrmann
Subjects: Cancer Research, Oncology, Incidence, Humans, Arrhythmias, Cardiac, Prospective Studies, cardiovascular diseases, Exercise, Capecitabine, Cardiotoxicity
Abstract: Background Physical activity may increase the risk of cardiotoxicity (myocardial ischemia, major arrhythmias) of 5-Fluorouracil, but this risk has never been investigated for its prodrug capecitabine. Patients and Methods One hundred and ninety-two consecutive patients undergoing capecitabine chemotherapy from December 1, 2010 through July 31, 2016 were prospectively evaluated. The baseline evaluation included electrocardiography (ECG) and echocardiography (2DE); a follow-up evaluation, including ECG and exercise stress testing (2DE in case of ECG abnormalities), was done after ≥10 days of treatment. Cardiotoxicity was suspected from ischemic ECG changes, new kinetic abnormalities at 2DE, Lown classification ≥2 ventricular arrhythmia, symptomatic arrhythmias, or positive stress test, and confirmed by a negative stress test after capecitabine washout. Results Cardiotoxicity was diagnosed in 32 patients (16.7%): six at rest and 26 during exercise. All 32 patients had ECG abnormalities: ST-segment changes (24 patients), negative T-waves (2) and/or arrhythmias: ventricular arrhythmias (14 cases), supraventricular tachycardia (2), complete heart block (1). Eight patients had typical symptoms, 6 had atypical symptoms, 1 had syncope, 17 (53%) were asymptomatic. Cardiotoxicity was more common in patients with atypical symptoms during daily life (OR = 15.7) and in those on a therapeutic schedule of 5 days/week (OR = 9.44). Conclusion Capecitabine cardiotoxicity is frequent, and often elicited by physical effort. Oncologists, cardiologists, and general practitioners should be aware of this risk. Active cardiotoxicity surveillance with ECG (and echocardiogram and/or stress testing in suspected cases) during therapy is recommended. Clinical Trials registration number CRO-2010-17.
Published: 2022
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43. A mudança no estilo de vida dos brasileiros frente à pandemia da COVID-19

Author: Gabriel Pereira Marques, Luiz Henrique Lepesqueur Botelho Lobão, Pedro Henrique Zorzetti Camara, Henrique de Castro e Santos, Fernanda Viel Barbosa, Victor Augusto Prates do Rego, Daniel Vasconcelos de Oliveira, Víctor Brunno Pinheiro Sampaio, Gabriel Alves Figueiredo de Sousa, and Otávio Bosi de Oliveira Fernandes
Abstract: OBJETIVO: Demonstrar a mudança no estilo de vida dos brasileiros frente à pandemia da COVID-19, com a finalidade de compreender seus principais impactos na saúde da população. MÉTODOS: Foi realizada uma revisão da literatura com busca no PubMed, Medline e SciELO. Utilizaram-se os descritores “Life Style AND COVID-19”, pesquisados no MeSH. Foram pesquisados artigos que configuraram estudos transversais descritivos que estavam no idioma português e que foram publicados entre 2020 e 2021. RESULTADOS: Saúde mental: Aumento dos sintomas psicopatológicos durante a pandemia, potencializados por sentimentos de ansiedade ocasionados pela mudança na rotina devido às medidas de distanciamento social. Atividade física: Diminuição da prática de atividades físicas e crescente de hábitos sedentários, como tempo em frente a televisores, celulares e monitores, tendo diversos efeitos negativos à saúde. Alimentação: Grande aumento do volume de compras em supermercados de alimentos ultraprocessados e com alta taxa energética, como pipoca, chocolate, congelados, doces, batatas fritas e sorvetes. Consumo de bebidas alcoólicas e tabagismo: Aumento do consumo de bebida alcoólica e na quantidade do consumo diário de cigarro durante esta fase, mediado pelos efeitos estressores da pandemia. CONCLUSÃO: O distanciamento social se constitui como uma medida essencial de proteção à vida, reduzindo a exposição, número de casos e consequentemente a morbimortalidade. Entretanto, essa medida pode resultar em consequências negativas no campo psicossocial e no estilo de vida populacional.
Published: 2022
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44. Prise en charge immédiate et postimmédiate des blessés psychiques, le modèle français des CUMP

Author: Fabrice Viel
Subjects: General Medicine, Pshychiatric Mental Health
Published: 2022
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45. Supply chain resilience in turbulent times: conceptual model and real-world use case*

Author: Silvio Luiz dos Santos Alvim, Ingra Viel de Farias, Enzo Morosini Frazzon, and Davi de Simas
Subjects: Control and Systems Engineering
Published: 2022
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46. Visibility model for enhancing supply chains resilience

Author: Ingra Viel de Farias, Silvio Luiz dos Santos Alvim, Davi de Simas, and Enzo Morosini Frazzon
Subjects: Control and Systems Engineering
Published: 2022
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47. A abordagem multidisciplinar e prognóstico da neoplasia esofágica: revisão literária

Author: Otávio Bosi de Oliveira Fernandes, Daniel Vasconcelos de Oliveira, Victor Augusto Prates do Rêgo, Gabriel Alves Figueiredo de Sousa, Víctor Brunno Pinheiro Sampaio, Gabriel Pereira Marques, Luiz Henrique Lepesqueur Botelho Lobão, Pedro Henrique Zorzetti Camara, Fernanda Viel Barbosa, and Henrique de Castro e Santos
Abstract: OBJETIVO: As neoplasias esofágicas são um tipo de doença que apresentam considerável morbidade e mortalidade mesmo com o tratamento adequado. Tendo em vista essa perspectiva, esse estudo visa promover uma análise do prognóstico e da abordagem multidisciplinar em relação a essa temática. MÉTODOS: Foi realizada uma revisão da literatura com busca no PubMed e BVSalud. Utilizou-se o descritor “Esophageal Neoplasms”, pesquisados no MeSH. Foram pesquisados artigos originais, trabalhos de conclusão de curso e letras para o editor que estavam nos idiomas inglês e português, os quais foram publicados entre 2006 e 2021. RESULTADOS: O câncer de esôfago possui um prognóstico insatisfatório e deficiente quando detectado tardiamente visto que na maioria dos casos é descoberto em fase de metástase 1. Seu tratamento busca uma interação multidisciplinar e um projeto terapêutico singular visando atender as necessidades do enfermo. Outra finalidade dessa intervenção terapêutica é um aprimoramento na sobrevida do paciente e redução nos níveis e índices de mortalidade e morbidade dos pacientes que apresentam o quadro clínico de neoplasia esofágica. CONCLUSÃO: Observou-se que por ser uma patologia com alta morbimortalidade, o desenvolvimento de uma abordagem multidisciplinar dos pacientes pode promover um prognóstico mental e físico com maior qualidade.
Published: 2022
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48. Data from Combined PET Imaging of the Inflammatory Tumor Microenvironment Identifies Margins of Unique Radiotracer Uptake

Author: Andreas H. Jacobs, Alexandra Winkeler, Michael Schäfers, Sven Hermann, Michael T. Kuhlmann, Cornelius Faber, Andreas Faust, Stefan Wagner, Katrin Schwegmann, Lisa Honold, Sonja Schelhaas, Inga B. Fricke, Lydia Wachsmuth, Thomas Viel, Benoit Thézé, Hayet Pigeon, and Bastian Zinnhardt
Abstract: The tumor microenvironment is highly heterogeneous. For gliomas, the tumor-associated inflammatory response is pivotal to support growth and invasion. Factors of glioma growth, inflammation, and invasion, such as the translocator protein (TSPO) and matrix metalloproteinases (MMP), may serve as specific imaging biomarkers of the glioma microenvironment. In this study, noninvasive imaging by PET with [18F]DPA-714 (TSPO) and [18F]BR-351 (MMP) was used for the assessment of localization and quantification of the expression of TSPO and MMP. Imaging was performed in addition to established clinical imaging biomarker of active tumor volume ([18F]FET) in conjunction with MRI. We hypothesized that each imaging biomarker revealed distinct areas of the heterogeneous glioma tissue in a mouse model of human glioma. Tracers were found to be increased 1.4- to 1.7-fold, with [18F]FET showing the biggest volume as depicted by a thresholding-based, volumes of interest analysis. Tumor areas, which could not be detected by a single tracer and/or MRI parameter alone, were measured. Specific compartments of [18F]DPA-714 (14%) and [18F]BR-351 (11%) volumes along the tumor rim could be identified. [18F]DPA-714 (TSPO) and [18F]BR-351 (MMP) matched with histology. Glioma-associated microglia/macrophages (GAM) were identified as TSPO and MMP sources. Multitracer and multimodal molecular imaging approaches may allow us to gain important insights into glioma-associated inflammation (GAM, MMP). Moreover, this noninvasive technique enables characterization of the glioma microenvironment with respect to the disease-driving cellular compartments at the various disease stages. Cancer Res; 77(8); 1831–41. ©2017 AACR.
Published: 2023
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49. Supplementary Fig. S1 from Premature senescence is a major response to DNA cross-linking agents in BRCA1-defective cells: implication for tailored treatments of BRCA1 mutation carriers

Author: Roberta Maestro, Alessandra Viel, Angela Caragnano, Elena Tonin, Laura Del Col, and Manuela Santarosa
Abstract: Supplementary Fig. S1 from Premature senescence is a major response to DNA cross-linking agents in BRCA1-defective cells: implication for tailored treatments of BRCA1 mutation carriers
Published: 2023
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50. Supplementary Table 2 from Candidate Genetic Modifiers for Breast and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

Author: Eitan Friedman, Antonis C. Antoniou, Georgia Chenevix-Trench, Paul D.P. Pharoah, Andrew Lee, Sue Healey, Daniel Barrowdale, Lesley McGuffog, Karoline B. Kuchenbaecker, Åke Borg, Marie Stenmark Askmalm, Hans Ehrencrona, Anna von Wachenfeldt, Johanna Rantala, Yael Laitman, Uffe Birk Jensen, Mads Thomassen, Inge Sokilde Pedersen, Anders Bojesen, Amanda Ewart Toland, Irene L. Andrulis, Sandrine Tchatchou, Gord Glendon, Anna Marie Mulligan, Gad Rennert, Phuong L. Mai, Mark H. Greene, Catherine M. Phelan, Muy-Kheng M. Tea, Georg Pfeiler, Daphne Geschwantler Kaulich, Christine Rappaport, Christian F. Singer, Andreas Berger, Vijai Joseph, Liying Zhang, Mark E. Robson, Lauren Jacobs, Marina Corines, Kenneth Offit, Csilla I. Szabo, Xianshu Wang, Noralane M. Lindor, Fergus J. Couch, Curtis Olswold, Manuel R. Teixeira, Jocelyne Chiquette, Adalgeir Arason, Grzegorz Sukiennicki, Katarzyna Jaworska-Bieniek, Katarzyna Durda, Jacek Gronwald, Cezary Cybulski, Lidia Feliubadalo, Joan Brunet, Conxi Lazaro, Ignacio Blanco, Orland Diez, Edith Olah, J. Margriet Collée, Helena C. van Doorn, Margreet G.E.M. Ausems, Nicoline Hoogerbrugge, Maaike P.G. Vreeswijk, Annemarie H. van der Hout, Hanne E.J. Meijers-Heijboer, Theo A.M. van Os, Kristiina Aittomäki, Heli Nevanlinna, Pedro Perez Segura, Miguel de la Hoya, Larry J. Copeland, Gustavo C. Rodriguez, Michael L. Friedlander, Marion Piedmonte, Muriel Belotti, Sylvie Mazoyer, Pascal Pujol, Olivier Caron, Olga M. Sinilnikova, Nadia Boutry-Kryza, Lisa Golmard, Laurence Venat-Bouvet, Laure Barjhoux, Isabelle Coupier, Francesca Damiola, Dominique Stoppa-Lyonnet, Claude Houdayer, Capucine Delnatte, Bruno Buecher, Brigitte Bressac-de Paillerets, Shan Wang-Gohrke, Barbara Wappenschmidt, Raymonda Varon-Mateeva, Norbert Arnold, Nina Ditsch, Kerstin Rhiem, Karin Kast, Hansjoerg Plendl, Doris Steinemann, Dieter Niederacher, Christoph Engel, Christian Sutter, Andrea Gehrig, Alfons Meindl, Tom Van Maerken, Kathleen Claes, Andrew K. Godwin, Trevor Cole, Steve Ellis, Shirley V. Hodgson, Rosemarie Davidson, Radka Platte, Patrick J. Morrison, Mary E. Porteous, Mark T. Rogers, M. John Kennedy, Lucy E. Side, Louise Izatt, Lisa Walker, Julian Barwell, Julian Adlard, Marc Tischkowitz, Jackie Cook, Angela Brady, Diana Eccles, Debra Frost, D. Gareth R. Evans, Claire Foo, Carole Brewer, Alan Donaldson, Judy E. Garber, Florentia Fostira, Athanassios Vratimos, Paolo Radice, Maria Grazia Tibiletti, Aline Martayan, Laura Papi, Giuseppe Giannini, Alessandra Viel, Stefano Fortuzzi, Frederique Mariette, Filomena Ficarazzi, Monica Barile, Giulietta Scuvera, Daniela Zaffaroni, Bernard Peissel, Siranoush Manoukian, Jeffrey N. Weitzel, Kathleen R. Blazer, Edye E. Conway, Javier Benitez, Cristina Martínez-Bouzas, Ana Osorio, Lars Jønson, Bent Ejlertsen, Anne-Marie Gerdes, Thomas V.O. Hansen, Susan L. Neuhausen, Yuan Chun Ding, Elizabeth J. van Rensburg, Cecilia M. Dorfling, Ramunas Janavicius, Saundra S. Buys, David E. Goldgar, Melissa C. Southey, Alex Miron, Wendy K. Chung, Jenny Lester, Sandra Orsulic, Beth Y. Karlan, Banu K. Arun, Timothy R. Rebbeck, Susan M. Domchek, Katherine L. Nathanson, Robert L. Nussbaum, Olufunmilayo I. Olopade, Encarna B. Gómez Garcia, Anna Jakubowska, Jan Lubinski, Laura Matricardi, Marco Montagna, Ana-Teresa Maia, Felicity Lose, Logan C. Walker, Amanda B. Spurdle, Frederieke H. van der Baan, Marjanka K. Schmidt, Matti A. Rookus, Bowang Chen, Stefan Wilkening, Ute Hamann, Douglas F. Easton, Rosalind A. Eeles, Penny Soucy, Jacques Simard, Rita K. Schmutzler, Anja Rudolph, Kirsten B. Moysich, Jenny Chang-Claude, and Paolo Peterlongo
Abstract: Supplementary Table 2. Results of the statistical analyses in BRCA mutation carriers.
Published: 2023
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