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In reaction to the Covid-19 pandemic, the Chinese authorities have installed visa restrictions and strict quarantine rules to prevent foreigners from spreading new infections to the country. This has disrupted a trend of increasing European Union (EU)-China travel and socio-economic exchanges. EU citizens living in or travelling to China have had to deal with the consequences of Beijing’s so-called Zero-Covid strategy. In view of quasi-closed borders, many Europeans have given up on living in or travelling to China. Those who have stayed have come up with strategies of adaptation, while European-owned firms have reacted by adopting initiatives such as doing business online or localising staff. Overall, the Chinese visa restrictions have added a new dimension to the debate on asymmetries in EU-China relations.

Objective The objective of this study was to develop the first edition of a Chinese evidence-based position paper on the management of oral leukoplakia (OLK). Study Design The consultant group for drafting the position paper consisted of 31 oral medicine specialists and 2 evidence-based medicine specialists. English studies (searched in PubMed, EMBASE, and the Cochrane Library) and Chinese studies (searched in China National Knowledge Infrastructure and WanFang) published before January 2018 were used. The quality of the study was assessed using the Grading of Recommendations Assessment, Development, and Evaluation grid, and the strength of the recommendations was determined based on the results of 3 rounds of voting among the consultant group members using the Delphi method. Results Twenty-two evidence-based guidelines for clinical management and monitoring of OLK were established in this position paper. A clinical path diagram for oral health practitioners was constructed based on the recommendations. Conclusion Current evidence suggests that management and monitoring of patients with OLK should be performed by experienced clinicians to control the lesion and for early detection of malignant transformation. However, all recommendations are based on evidence of low or extremely low quality and may require further modification as new evidence is produced.

Highlights • Standard procedures and appropriate assessment of exercise are proposed for the commonly used animal models related to chronic exercise (e.g., treadmill running, voluntary wheel running, swimming exercise, and resistance exercise) in cardiovascular research. • Optimal design of animal exercise studies in cardiovascular research should consider the choice of exercise models, control of exercise protocols, exercise at different stages of disease, and other factors, such as age, sex, and genetic background. • An optimal design for studying exercise-induced physiological cardiac growth and its related beneficial effects against cardiovascular diseases is presented., Growing evidence has demonstrated exercise as an effective way to promote cardiovascular health and protect against cardiovascular diseases However, the underlying mechanisms of the beneficial effects of exercise have yet to be elucidated. Animal exercise studies are widely used to investigate the key mechanisms of exercise-induced cardiovascular protection. However, standardized procedures and well-established evaluation indicators for animal exercise models are needed to guide researchers in carrying out effective, high-quality animal studies using exercise to prevent and treat cardiovascular diseases. In our review, we present the commonly used animal exercise models in cardiovascular research and propose a set of standard procedures for exercise training, emphasizing the appropriate measurements and analysis in these chronic exercise models. We also provide recommendations for optimal design of animal exercise studies in cardiovascular research, including the choice of exercise models, control of exercise protocols, exercise at different stages of disease, and other considerations, such as age, sex, and genetic background. We hope that this position paper will promote basic research on exercise-induced cardiovascular protection and pave the way for successful translation of exercise studies from bench to bedside in the prevention and treatment of cardiovascular diseases., Graphical abstract Image, graphical abstract

COVID-19 first appeared in December of 2019 in Wuhan, China. Since then it has become a global pandemic. A robust and scalable diagnostics strategy is crucial for containing and monitoring the pandemic. RT-PCR is a known, reliable method for COVID-19 diagnostics which can differentiate between SARS-CoV-2 and other viruses. However, PCR is location dependent, time consuming and relatively expensive. Thus, there is a need for a more flexible method which may be produced in an off-the-shelf format and distributed more widely. Paper-based immunoassays can fulfill this function. Here we present the first steps towards a paper-based test which can differentiate between different between the Spike protein of various coronaviruses, SARS-CoV-1, SARS-CoV-2 and CoV-HKU1 with negligible cross reactivity for HCoV-OC43 and HCoV-229E in a single assay which takes less than 30 minutes. Furthermore, our test can distinguish between fractions of the same Spike protein. This is done by an altered assay design with four test line locations where each antigen builds a unique, identifiable binding pattern. The effect of several factors, such as running media, immunoprobe concentration and antigen interference is considered. We find that running media has a significant effect on the final binding pattern where human saliva provides results while human serum leads to the lowest signal quality.

Background Lysine succinylation is a naturally occurring post-translational modification (PTM) that is ubiquitous in organisms. Lysine succinylation plays important roles in regulating protein structure and function as well as cellular metabolism. Global lysine succinylation at the proteomic level has been identified in a variety of species; however, limited information on lysine succinylation in plant species, especially paper mulberry, is available. Paper mulberry is not only an important plant in traditional Chinese medicine, but it is also a tree species with significant economic value. Paper mulberry is found in the temperate and tropical zones of China. The present study analyzed the effects of lysine succinylation on the growth, development, and physiology of paper mulberry. Results A total of 2097 lysine succinylation sites were identified in 935 proteins associated with the citric acid cycle (TCA cycle), glyoxylic acid and dicarboxylic acid metabolism, ribosomes and oxidative phosphorylation; these pathways play a role in carbon fixation in photosynthetic organisms and may be regulated by lysine succinylation. The modified proteins were distributed in multiple subcellular compartments and were involved in a wide variety of biological processes, such as photosynthesis and the Calvin-Benson cycle. Conclusion Lysine-succinylated proteins may play key regulatory roles in metabolism, primarily in photosynthesis and oxidative phosphorylation, as well as in many other cellular processes. In addition to the large number of succinylated proteins associated with photosynthesis and oxidative phosphorylation, some proteins associated with the TCA cycle are succinylated. Our study can serve as a reference for further proteomics studies of the downstream effects of succinylation on the physiology and biochemistry of paper mulberry.

China's low-carbon energy transition depends on the power sector taking the lead. In this assessment, we seek to answer three questions about China's power sector transformation: (1) Is the power sector transition on track, in terms of non-fossil and renewable capacity and output? (2) Are market reforms in the power sector a prerequisite for China's low-carbon transition? (3) Do efforts at international experience sharing and topics of cooperative research require adjustment? The paper assesses that China is making steady progress at decarbonising in some sectors, such as the power sector and transport, while others will require more time to assess. On market reforms, however, progress has been slow and appears likely to remain so. While to date, international cooperation on power sector cooperation has focused on evaluating the potential benefits of a target market model in China, the paper argues that efforts to highlight progress in technology or policy - both inside and outside China - may have greater impact on future policy discussions.

Objective: The aim of this study was to explore the geographic distribution and number of papers published in international and Science Citation Index (SCI)-indexed cytology journals based on their country of origin. Materials and Methods: A country-based geographic analysis of studies published over a 5.5-year period from January 2016 to June 2021 in 5 cytopathology journals indexed as SCI and SCI-E with an impact factor higher than 1 (Cancer Cytopathology, Cytopathology, Diagnostic Cytopathology, Acta Cytologica, and CytoJournal) and papers categorized as “original” and “other” was performed. Results: A total of 3,063 papers were found, with 1,466 (47.8%) categorized as “original” papers and 1,597 (52.1%) designated as “other” papers. These papers were submitted from 62 different countries. The five countries with the greatest number of papers were the USA (38.4%), India (16.8%), Japan (7.4%), Italy (5.5%), and Brazil (3.1%). A general subgroup analysis was also performed on the original studies without a country breakdown. Cytomorphological, cytomorphological-immunohistochemical, and molecular assessments compose 38.5%, 45.7%, and 15% of the subgroups, respectively. Conclusion: The number of academic papers originating from developing countries in the field of cytopathology has increased in recent years. Although most scientific papers are produced in developed countries, the rate in these countries is much lower than that in some developing countries as the rate of academic growth in developed countries has stabilized. Despite the widespread and sophisticated implementation of cytology in daily practice in Western European countries outside the UK, such as Germany and the Netherlands, and in Scandinavian countries and other developed countries, such as Australia and Canada, these countries rank in the middle to lower end of countries producing cytology papers. Meanwhile, there has been an increase in the number of cytology papers published by authors from Southern European countries, such as Italy (ranked 4th) and Spain (ranked 6th), and Turkey (ranked 8th). There is a remarkable increase in cytology papers originating from Asia, particularly India, Japan, and China. Summary: We aimed to present a basic survey of the geographic distribution of manuscript submissions to high-impact cytopathology journals and to point out emerging trends in cytology utilization and basic research. However, our results show that the landscape of cytology is changing and suggest geographic regions that are ripe for the production of novel “points of view” and new research findings.

Paper money was first used in China as early as the sixth century AD. Since that time, counterfeits have circulated in parallel with authentic paper money. After WWII the interest of art collectors in historical emergency paper money surged and counterfeiting became a complex phenomenon. In fact, the use of scientific investigation for determining the authenticity of historical paper money is still limited to few cases. In this work nine pieces of Chinese paper money (from the fourteenth to nineteenth century) were investigated by combining non-invasive MA-XRF imaging and Raman spectroscopy. Analytical results on the paper money demonstrated how the complementary use of both non-invasive techniques can provide an excellent tool for discriminating modern materials from historical ones, allowing us to identify seven counterfeits in the set of nine investigated paper moneys.

Objective This study collected randomized controlled trials (RCTs) published in the social sciences in China and assessed their risk of bias and reporting quality. Study Design and Setting Three databases were systematically searched for publications from January 2000 to June 2020 for RCTs in the social sciences published by Chinese researchers. The risk of bias was assessed using the Cochrane Collaboration Risk of Bias Tool (CCRBT), and reporting quality was assessed using the Consolidated Standards of Reporting Trials for Social and Psychological Interventions (CONSORT-SPI). Results A total of 316 RCTs were identified, including 204 articles in English and 112 articles in Chinese. The most frequently researched interventions focused on education (33.9%), and the most frequently studied population were students (32.9%). Eighty-seven percent of RCTs had intermediate reporting quality. Twenty-four of the 43 CONSORT-SPI sub-items had a compliance rate of less than 50%. Most RCTs had an unclear risk of bias for blinding outcome assessors (84.5%), blinding participants and personnel (82.9%), allocation concealment (73.1%), and random sequence generation (68.0%). A low proportion of CONSORT-SPI items were reported and, high proportion of the papers had unclear risk of bias. Conclusion The quality and reporting of RCTs in the social sciences needs improvement in China, especially for reporting methods and results. Most studies had an unclear risk of bias as they lacked important methodological information.

The Tibetan Plateau works as an important environmental and ecological barrier for the Asian continent. The researches on Tibetan environment and ecology are becoming extensive, but there is no systematic summary of research hotspots and trends in this field. Here, we analyzed 9180 publications retrieved from the WOS and CNKI during 2000 ~ 2020. The characteristics of publication, keywords with a 5-year interval and co-occurrence analysis were carried out so as to reveal the evolution and development trends of topics. The results show that articles increase dramatically since 2012. Except for common concerns like evolution, climate change, and precipitation, diversity was been studied more by Chinese scholars, while the USA, Germany, UK, and Australia researchers focused more on adaptability, basin western Tibet, lake, barley, and ore-related themes, respectively. Besides, China closely collaborated with the USA, Australia, and Germany in topics of evolution, climate change and degradation, precipitation, and diversity. The institutions located in Chinese different economic regions focused on different research keywords, such as vegetation, growth, trace elements, and geochemistry. The CAS contributed the most articles with 4254, showed advantages both in quantity and quality. Few articles were published by researchers affiliated to Free University of Berlin but with higher citations. It is the only one institute outside of China in the top 20. Main research hotspots include climate change, geology, and diversity. In future researches, ecological management and rehabilitation of mining area and tailings ponds, waste disposal, and changes of soil and water quality are worthy of attention and funding.

Objectives To present the history and potential for development of evidence-based (EB) social work in China. Study design and setting The conception and methodology of EB social work is a potential strategy to support high quality development of social work in China. This article documents and analyzes the progress of EB social work in China. We focus on current research, reasons, challenges, and strategies. Results EB social work started late in China. The number of EB social work literature and systematic reviews has increased since 2004. The development of EB social work has been uneven nationally with few practitioners and decision makers involved. However, more and more social work researchers received training in evidence-based practice through national workshops and conferences. Conclusion EB social work faced various challenges, but there are now more opportunities for EB social work development in China. Researchers, practitioners, managers and decision makers are encouraged to work together to establish a thorough methodological system and use existing evidence as much as possible when carrying out social work programs and services.

This research develops a difference-in-differences (DID) model to explore the relationship between environmental policy (The Measures for the Administration of Permits for the Discharge of Key Water Pollutants in the Huaihe and Taihu River Basins, MAPD) and the performance of firms involved in the paper and paper products industry (MPP) in China. Cost and innovation are introduced as mediators to explore the mediating effects. A firm-level dataset from 1998 to 2007 is adopted for empirical study. The findings support the positive role of the MAPD, and the average treatment effect is 0.016.The heterogeneity analysis shows that the MAPD exerts a positive impact on non-state-owned and small-scale enterprises, with coefficients of 0.018 and 0.021, respectively. Moreover, MAPD increases enterprise costs harming firm performance. On the other hand, it can promote firm performance by improving innovation ability.

Since its first detection in China in December 2019, COVID-19 has spread with alarming speed and lethality, thoroughly transforming daily life around the world in ways that few could have foreseen....

Background Burning mouth syndrome is a syndrome with tongue as the main affected site and burning pain as the main complaint. Although a variety of therapies have been reported to treat BMS, there is a lack of widely recognized therapies and it is still a dilemma for clinicians to treat BMS. Objective To develop the position paper and provide the references for clinical practice of BMS in China. Methods Under the guidance of WHO (World Health Organization) Handbook for Guideline Development, we used the GRADE (Grading of Recommendations Assessment, Development and Evaluation) approach as a tool to develop this position paper in the following steps: setting up the groups, formulating the clinical questions and choosing the outcomes, retrieving and synthesizing of evidence, assessing the evidence, investigating the patients' values and preferences, developing the recommendations, reviewing the recommendations, and writing the position paper. Results The 27 recommendations were formed from the following 7 aspects: pre-treatment examination, removal of stimuli, medication, physical therapy, psychological therapy, and antipsychotics. There are 3 strong recommendations and 12 weak recommendations in pre-treatment examination and removal of stimuli, as well as 12 weak recommendations in therapies. Conclusion The Chinese position paper for management of BMS has been developed, which could provide the references for clinical practice of BMS in China. Twenty-seven recommendations were formed based on consensus of experts on the balance of benefits vs side effects, evidence, cost, and patients' values and preferences, although the quality of evidence is relatively low.

The printing industry has been affected by the great technological advances the world is witnessing. This has one way or another, led to a difference in the expected production percentages of publications in general, as well as the consumption and demand ratios. This had a direct impact on the paper industry. This also led to changing production trends, so this study examined the effect of these proportions locally and globally on the printing industry. It sought to present proposed solutions to achieve market growth and industry growth, according to global trends, and to benefit from this in the local market. The research aimed to reach through the use of different computational methods, quantitative analysis and standard modeling methods to production and consumption ratios and the extent of global and local demand for different paper products and the relationship of those proportions to global technological progress. As well as knowing the impact of this on the printing industry and providing proposed solutions to achieve growth in the industry and the market. And building forecasts of demand for paper in major regions of the world from 2005 to 2050. The method used in this research is the analytical descriptive approach. Through studying the reports and doing analytical and survey studies, the study concluded that the demand for health paper and packaging products will be much greater than printing and writing papers globally all over the world. As for regional variations in all types of products, it is estimated that the highest growth patterns are in Asia, Africa, South America, and Eastern Europe. It is estimated that Western Europe and North America face a slight decrease in paper product printing and an expected increase in demand for packaging products. Likewise, the potential root changes in China (due to stable population growth) and consumption patterns related to consumer aging in Western Europe and North America should be taken into account. Also, the demand for paper and packaging products has grown significantly, and Africa will constitute a major market for investments.

This article aims to outline main directions of the security strategy of the People’s Republic of China basing on the analysis of the Defence White Paper of July 2019, the political practice of the Beijing authorities as well as internal and international situation. Having analysed the above mentioned areas, the author concludes that the contemporary strategy of the PRC is internally subordinated to maintaining territorial, political and social integrity, including primarily legitimization of the power of the Communist Party of China. Externally, the strategy is oriented at reversing the unfavourable balance of forces in the Asia-Pacific region and weakening of the US military advantage. Those two directions determine the activities of the Chinese state in such specific areas as: modernization of the People’s Liberation Army (PLA), the relations with Taiwan and claims concerning South China Sea. The Defence White Paper is aimed at contrasting the unilateral and hegemonic policy of the United States (as the authors of the document see it) with the defensive and moderate activities of China. The narration serves to convince international players to remain neutral or engage in collaboration with China in the face of intensifying military, economic and political pressure on the part of the USA. China has entered a “critical moment” of its development and the response of the Beijing authorities to the challenges of internal development and external pressures will determine whether in the 21st century it will become a superpower.

If there was a single trigger for the “white paper” uprising that has been sweeping China over the past few days, it was events in Ürümchi, the capital of Xinjiang province. Xinjiang’s lockdown has been the most severe in China, with many residents unable to leave their homes for nearly four months. When ten or more residents, mostly Uyghur Muslims, were barred from escaping a blaze, their apartment block became a death trap. The doors, it is said, had been externally bolted.

The Guidelines on Building a Market-Oriented Green Technology Innovation System, which was released by China in 2019, has become a powerful signal to guide the development of green technology innovation (GTI). In the current digital strategy of China, the public media has become a key factor for promoting the transparency of enterprise environmental information. This paper measures the GTI efficiency of the listed paper enterprises in China as well as incorporating media attention into the research framework to explore the influencing factors of GTI of the listed paper enterprises in China during the digital economy era. The results showed that a positive media report had a positive impact on GTI and has become a new driving factor in promoting sustainable production in the digital era. Government support and openness also have a positive impact on GTI. However, negative media reports, environmental regulations, and technological innovation abilities have an inhibitory effect on the GTI efficiency of paper making enterprises.

In China, master's students in humanities and social sciences (HSS) are becoming the main target of Chinese-language predatory journals. Existing research has not paid enough attention to why these students publish papers in Chinese-language predatory journals. This research interviewed 30 HSS master's students with different majors using semi-structured interviews and Grounded Theory to analyze the data; it found that research discrimination, research context, self-awareness, and individual demand are the main reasons why students publish papers in Chinese-language predatory journals. This study provides the following suggestions in an effort to solve the problem of Chinese-language predatory journals. First, the Chinese government should draw up a blacklist of Chinese-language predatory journals. Second, the research evaluation departments of Chinese universities and research institutions should evaluate the research results of HSS master's students based on this list. Third, Chinese universities or scientific research institutions should strengthen the training of HSS master tutors and increase their awareness of Chinese-language predatory journals. And finally, Chinese HSS master's students should be taught about the hazards of Chinese-language predatory journals in research integrity and ethics courses, and refuse to publish papers in Chinese-language predatory journals.

Objective To share the experience of promoting GRADE in China. Study Design and Setting We designed the study and collected data on the following three aspects of the GRADE in China: the key activities related to GRADE, the main achievements of the GRADE, and potential challenges and future opportunities. Results Three GRADE centres have been established in China since 2011. Seventeen articles of the GRADE working group have been translated and published in Chinese, and 31 articles have been written by Chinese scientists in Chinese to introduce and interpret the GRADE approach so far. More than 50 GRADE workshops and meetings have been held by GRADE centres in China, covering two-thirds of all provinces and autonomous regions of China. The percentages of societies from the Chinese Medical Association (CMA) and the Chinese Medical Doctor Association (CMDA) that used the GRADE system to develop guidelines were 30% and 18%, respectively. Conclusion Over the past decade, China has made progress in promoting the GRADE system and Chinese GRADE centres have made a significant contribution.

This document was prepared thanks to the collective expertappraisal, carried out by the Anses’expert group‘GECUCovid-19’(ANSES opinion 2020-SA-0037), chaired by Sophie Le Poder and whose members for the animal health component are cited in the authors.; International audience; In late December 2019, an outbreak of clustered cases of pneumonia associated with a novel coronavirus was reported by the Chinese authorities to the World Health Organization (WHO). Several initial confirmed cases were linked to a wetmarket selling live animals and seafood products in Wuhan(Hubei province), China (Huang et al.,2020). On 30 January 2020, the WHO declared the outbreak a Public Health Emergency of International Concern. On 11 February 2020, the causative pathogen was officially named Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), responsible for Coronavirus Disease 2019 (COVID-19) (DuToit, 2020). Severe Acute Respiratory Syndrome Coronavirus 2 is mainly transmitted from person to person, by direct or indirect contact, through infectious microdroplets emitted wheninfected individuals spit, sneeze or cough (Bernard Stoecklin et al.,2020). The massive circulation of this new pandemiccoronavirus with a probable zoonotic origin raised questions on its ability to spillover to animal species and on the potential consequences of such events on both animals and humans. This public health concern came to the attention of animal health authorities given the close contacts between humans and domestic animals. Therefore, in France, the French Agency for Food, Environmental and Occupational Health and Safety (ANSES) established an Emergency Collective Expert Appraisal Group (Groupe d’Expertise Collective d’Urgence, GECU‘Covid-19’). The GECU ‘Covid-19’ urgently convened on 4 March 2020 and 8 April 2020 to conduct an evaluation of the potential role of domestic animals in the ongoing COVID-19 pandemic.

While participation in the international division of labor has led to rapid economic development, it has also resulted in pressing environmental issues in China. In the context of “building a resource-saving and environment-friendly society” and the current sustainability requirements, research on the environmental impact of Chinese paper companies from the perspective of Environmental Information Disclosure (EID) policy and trade has not yet reached a consensus. This study constructs an analytical framework for the EID policy impact mechanism and trade on the environmental effects of the paper industry and enterprises. It explores the direct and indirect effects of EID policy and import-and-export trade on the paper industry environmental effects using the Propensity Score Matching and Difference-in-Differences (PSM-DID) model. EID positively impacts the pollution reduction of enterprises mainly through the technical effect. Export trade positively impacts the reduction of enterprises’ emissions through the technology effect. However, the demand of the international market increases the pollution from the paper industries, which has a negative impact. Importing will enable enterprises to obtain greater price advantages which can alleviate and transfer the costs brought by EID. This study analyzes the impact of trade on the environmental effects of Chinese paper enterprises and identifies the impact of China’s EID policy and trade on enterprises’ pollution emissions. It provides a theoretical and practical foundation for the Chinese government to formulate environmental and trade policies.

Background Brucellosis, as a serious zoonotic infectious disease, has been recognized as a re-emerging disease in the developing countries worldwide. In china, the incidence of brucellosis is increasing each year, seriously threatening the health of humans as well as animal populations. Despite a quite number of diagnostic methods currently being used for brucellosis, innovative technologies are still needed for its rapid and accurate diagnosis, especially in area where traditional diagnostic is unavailable. Methodology/Principal findings In this study, a total of 22 B cell linear epitopes were predicted from five Brucella outer membrane proteins (OMPs) using an immunoinformatic approach. These epitopes were then chemically synthesized, and with the method of indirect ELISA (iELISA), each of them displayed a certain degree of capability in identifying human brucellosis positive sera. Subsequently, a fusion protein consisting of the 22 predicted epitopes was prokaryotically expressed and used as diagnostic antigen in a newly established brucellosis testing method, nano-ZnO modified paper-based ELISA (nano-p-ELISA). According to the verifying test using a collection of sera collected from brucellosis and non-brucellosis patients, the sensitivity and specificity of multiepitope based nano-p-ELISA were 92.38% and 98.35% respectively. The positive predictive value was 98.26% and the negative predictive value was 91.67%. The multiepitope based fusion protein also displayed significantly higher specificity than Brucella lipopolysaccharide (LPS) antigen. Conclusions B cell epitopes are important candidates for serologically testing brucellosis. Multiepitope fusion protein based nano-p-ELISA displayed significantly sensitivity and specificity compared to Brucella LPS antigen. The strategy applied in this study will be helpful to develop rapid and accurate diagnostic method for brucellosis in human as well as animal populations., Author summary Brucellosis is one of the most important zoonosis in the world and has caused tremendous economic losses in agriculture and animal husbandry in many countries. Developing rapid, sensitive and specific diagnostic methods is very important for early detection and treatment of brucellosis patients. In this study, a novel diagnostic technique, nano-ZnO modified paper ELISA, was established. The antigen used in this technique was a fusion protein containing multiple B cell epitopes, which were predicted from Brucella major outer membrane proteins such as Bp26, Omp31, Omp16, Omp2b and Omp25. Comparing to traditional LPS antigen, this multiepitope based antigen displayed considerably higher sensitivity and higher specificity in laboratory. With the strategy described in this paper, more efficient epitopes and protein antigen can be identified in the future. Currently, LPS antigen is only prepared from live Brucella, while protein antigen can be produced in large quantities in prokaryotic expression system. In addition to nano-p-ELISA, this protein antigen can also be used for development other methods such as fluorescent polarization assay (FPA) and immunochromatographic assay (ICA) to meet the varied demand for brucellosis testing.

Waste paper, an essential substitute for wood and other plant-based fibers in paper making, is an indispensable part of the circular economy; yet, the impacts of China's ban on global waste paper cycles have not been well understood. We modeled the evolution of the global waste paper trade network during 1995-2019. We found that the cumulative trade volume of global waste paper reached 1010 million tons in the last 25 years and showed a downward trend since 2015. The global import center of waste paper experienced a transfer from Europe to East Asia and then to Southeast Asia. The ban has stimulated some developed countries to reduce the exports of unsorted waste paper since 2017, but for many major importers their changes in waste paper trade patterns were related to waste paperboard, which was not banned by China, suggesting that this import change trend may be inevitable and irrespective of China's ban. Besides, India has replaced China to become a new import hub of unsorted waste paper. Our results lay a foundation for exploring the evolution of the future global solid waste cycle under the background of zero import of solid waste increasingly implemented by China and many other developing countries.

To determine the occurrence of mineral oil hydrocarbons (MOH) in food contact papers in China, and to investigate the potential sources of MOH contamination, a total of 159 food contact papers and raw materials were analysed by off-line solid-phase extraction-gas chromatography flame ionisation detection (SPE-GC-FID) and a GC-MS method. The migration of MOH from food contact papers into Tenax, olive oil or 50% ethanol under the worst foreseeable conditions of use was determined. The results indicated that the occurrence of MOH in China is of a potential health risk concerning the migration of mineral oil saturated hydrocarbons (MOSH) and mineral oil aromatic hydrocarbons (MOAH) which were detected in 82.6% and 50.4% of samples, respectively. Migration of MOSH from 47.9% of samples was higher than 2 mg/kg and migration of MOAH from 32.2% samples exceeded 0.5 mg/kg in case of the worst foreseeable condition of use. The highest mean migration of MOSH and MOAH were found in packaging papers for long-term storage (more than 6 months), with mean migration of 91.2 mg/kg and 1.4 mg/kg, respectively. Migration of MOH from printed paper was considerably higher than that of unprinted paper, validating previous findings that the printing ink is the predominant source of MOH contamination in food contact papers. Migration of MOH from paper bowls used for packing instant noodles was relatively low, suggesting the internal hollow layer may be acting as a functional barrier that could block the transfer of MOH (up to C28) through the gas phrase, even though the outer layer was made from recycled paper. High concentrations of MOSH and MOAH were also detected in de-foamers, adhesives and rosin sizing agents, indicating that the MOH contamination caused by the use of raw materials and additives should also be taken into consideration.

This article reports a critical discourse analysis of the legitimation strategies used in two Chinese government white papers about trade frictions between China and the United States. Drawing on the legitimation framework advanced by van Leeuwen to political discourse, it shows how the white papers use four main legitimation strategies: authorization, moralization, rationalization, and integration. It argues that the Chinese government uses these strategies to legitimate its responses to US trade policy and delegitimate the US government’s motives for initiating/escalating tensions. This article also discusses how the use of these legitimation strategies draws from certain traditional Chinese cultural values, such as Confucianism, the culture of face, and collectivism. This article is a part of a larger research project studying discursive strategies in trade friction discourse and hopes to shed light on the attributes and functions of this type of discourse.

Projects 2 and 3 We are developing an information source-set robustness and statistical reliability measure or index for applications in political psychology and political philosophy. The specific context for application is Sino-Western relations, anti-China propaganda, and anti-China sentiement. We are designing two naturalistic studies as pilots, to be further developed into larger naturalistic studies, or else quasi-experiments or full experiments. The pilots and a meta-analysis of similar studies will be used to ascertain required sample sizes to achieve statistical power of 80% with meaningful minimum effect sizes (dependent on test statistics chosen.). Abstract 2 (Draft) : The first experiment is intended to test how much knowledge of the upstream information sources and information source sets of Li-Meng Yan’s COVID-19 article, and of the pre-reviews of that article, inform the public’s reception of the article and their subsequent level of anti-China sentiment. The specific statistical models to be deployed are yet to be determined, and will depend upon initial pilots and meta-analyses used to determine minimum sample sizes and appropriate independent, or predictor, variables.

This paper investigates ‘newspaper reading groups’ (dubaozu) in the People’s Republic of China (PRC) from 1951–1955, and how these groups reflected the daily practice, possibilities, and limits of ...

The category of household and sanitary products is the most important category in the paper industry, because it is related to people’s daily lives all around the world. This category is seeing a rapid increase in consumption, while consumption in other categories, such as printing or writing paper, is presently declining. China is the largest manufacturer, as well as the largest consumer of household and sanitary paper. Nowadays, environmental consciousness and concerns are rising in China and have started to influence customers’ behavior in selecting and using paper products. In the present study, surveys were conducted of the paper industry, the retail market for paper, and end consumers of paper. The relationship between new challenges of the paper industry and consumers’ environmental concerns has been investigated and reported.

Background: The Western Ontario and McMaster University osteoarthritis index (WOMAC) is the most commonly used indicator of disease-specific outcome in knee osteoarthritis (KOA) for its convenience and reliability. It has two formats— the paper-based WOMAC (p-WOMAC) and the electronic WOMAC (e-WOMAC). In China, the p-WOMAC has been widely used though e-WOMAC is yet untested. This study aims to test whether e-WOMAC is consistent with the p-WOMAC before and after the intervention. Methods: A total of 240 patients from Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine (SHUTCM) will be randomly assigned in two groups which are named as group A and group B. This study is divided into three stages. In the first stage, patients in group A will be evaluated first by p-WOMAC and then by e-WOMAC. Patients in group B will be evaluated by e-WOMAC and then by p-WOMAC. In the second stage of the study, drug interventions will be implemented. 200mg celecoxib will be administered orally once a day starting from the second day of enrollment for a period of 21 days. The third stage is the consistency evaluation stage after intervention. The post-intervention evaluation will be conducted after administration. Patients in group A will be evaluated first by e-WOMAC and then by p-WOMAC. Patients in group B will be evaluated first by p-WOMAC and then by e-WOMAC. In order to avoid the possible bias because of patients’ potential memory, e-WOMAC and p-WOMAC will be taken for each patient at 15 minutes apart in the first and third stages. The comparison will include the overall score of the WOMAC, the score of each subscale and the score of individual items. Comparing the e-WOMAC with the p-WOMAC, the primary outcome of the study is the mean score difference in WOMAC, and the secondary outcomes are the score differences in three WOMAC subscales: pain, stiffness, and physical function. Discussion : This study will test reliability and comparability between e-WOMAC and p-WOMAC. Meanwhile, we will also collect and provide participants’ feedback after comparing two formats of the WOMAC. If the results are favorable, our findings will serve to demonstrate the equivalence of each version of the WOMAC so that it can be implemented in specialized medical activities. Likewise, our results will further demonstrate the feasibility of e-health for the personalize KOA treatment. Trial registration: ChiCTR, ChiCTR2100050914. Registered on 8 Sep 2021, https://www.chictr.org.cn/showproj.aspx?proj=133521 Keywords: Chinese electronic version of WOMAC, Verification, Protocol

The article is devoted to the analysis of the PRC’s first normative political document on the Arctic — the White Paper “China’s Arctic Policy” (January 2018). The authors characterize China’s new viewpoints of Arctic policy, analyze the international and domestic background, describe the main principles and positions, outline the goals and importance of this policy. The White Paper is a Chinese program for the Arctic governance, which determines China’s participation in Arctic affairs at present and in the future. The guidelines of this participation are: deepening the exploration and understanding of the Arctic, protecting the environment of the region and addressing climate change, utilizing Arctic resources in a lawful and rational manner, participating actively in the Arctic governance and international cooperation, promoting peace and stability in the region. The White Paper will contribute to enhancing mutual understanding between China, the Arctic countries and other stakeholders in the region, helping Chinese (especially the younger generation) understand the changes in the Arctic and improve their knowledge about the environment. The document generally reflects the rules and ways of the PRC’s participation in the Arctic governance, allows different Chinese departments, organizations and individuals more effectively coordinate and manage Arctic affairs. China as a “Near-Arctic State” is an important stakeholder, an active participant and a constructer; it makes a special contribution to Arctic affairs in accordance with international law. On the basis of the Chinese conception of creating a “Community of Common Destiny of Mankind” together with Arctic states and international community, the PRC understands, protects, develops the Arctic and participates in the Arctic governance, actively promotes cooperation in the construction of the Arctic part of the “Belt and Road”, safeguards and promotes peace, stability and the sustainable development of the region. Acknowledgements. The article was prepared as part of the “Project of Philosophy and Social Science Research of the Ministry of Education” (16ZD029).

A filter paper was functionalized with β-cyclodextrin and citric acid via esterification reaction for the removal of dyes and Cu ions from aqueous solutions. The adsorption capacity and removal performance of the modified filter paper (MFP) was investigated using static and dynamic adsorption experiments. The static adsorption data fit well the Langmuir and pseudo-second-order models, and the adsorption capacity of Methylene Blue (MB), Brilliant Green (BG), Rhodamine-B (RB) and Cu(II) over the MFP were 124.6 mg/g, 130.4 mg/g, 99.7 mg/g and 39.1 mg/g, respectively, which are much higher than the unmodified filter paper (below 2 mg/g). Even better, the decolorization performance and Cu(II) removal of MFP are remarkable in dynamic adsorption. The effluent can reach the National Standard for dyeing and finishing of textile industry of China after three cycles in a continuous filtration-adsorption system. This method provides a new pathway to achieve high efficiency removal of dyes and metal ions from wastewater.

Electronic paper is now closer than ever to changing the way we read, write, and study. This was hailed as a revolution so profound that some see it as second only to the invention of the printing press in the 15th century. In this study, four analytical methods, which included statistical analysis, technology decomposition, multistage technological evolution and growth potential analysis were used. Results showed that technological research on business has great potential for development and vast market, and it would be another 16 years before the limit could be reached for patents. A great deal of technology breakthrough has been achieved during 1992 and 2012. The four major countries for printed electronic paper development are Japan, USA, South Korea and China. However, China has a gap compared with other countries, as the key technology was held by large enterprises. The apparatus for printed electronic paper has been the major focus in China. The key point for research on printed electronic paper was focused on devices for presentation and light emission, and related semiconductor devices.

As a type of official government document, government white papers are issued by the government to set out facts and take a position on a major issue or an international concern, possessing the characteristics of timeliness, publicity, objectivity, and authenticity. Using the theory of functional equivalence as the theoretical basis and the white paper named Fighting COVID-19: China in Action, which was published on June 7, 2020, as the research data, this paper analyzes some translation methods and strategies used in the translation of the white paper from the lexical and the syntactic level, providing some theoretical references to it.

The first cases of the novel coronavirus disease (COVID-19), previously known as 2019-nCoV, were reported in late December 2019 in Wuhan, China (Wu, Zhao, Yu B, et al 2020). The virus then spread to Malaysia and Thailand and eventually to the Americas, Europe, Australia and Africa. On the 11thof March 2020 the World Health Organisation (WHO) declared the COVID-19 a global pandemic. This concept paper explores the potential impact of COVID-19 on poverty stricken and conflict-ridden communities in Sub-Sahara Africa. In doing so, the paper also explored the implications for public health professionals working with these communities, including recommendation for future policy development.

The cultural background of the proliferation of early paper in Central Asia and its use outside China has rarely been explored. Since written sources are inconclusive regarding the origins and spread of papermaking, archaeological and material evidence assumes increased importance. The preserved manuscripts found along the Silk Road have been used as a key source in the study of religion, literature and the cultural history of Central Asia. They have, however, rarely been viewed as artefacts in their own right, with their own specific form and produced by a specific technology. Paper is one of the most important physical aspects of a manuscript and at the same time bears witness to early papermaking technologies. As an introduction to the vol­ume Asian paper as writing support, this article outlines the early history and technology of pa­permaking as revealed by the oldest manuscripts in existence, those found along the Silk Road.

In the past decade, the Chinese paper industry, which is highly polluting and energy intensive, has shown overall increases in production, sales, income, and profit, although the growth rate has declined. Overall, China’s paper industry exhibits small-scale and scattered distribution, characterized by continuous overcapacity and outdated technical knowledge. This has inevitably resulted in a variety of serious environmental problems during its development. Owing to the environmental problems resulting from the development of the paper industry, various environmental regulatory policies and measures have been adopted in China, mainly command-and-control, market-based, and voluntary policies and measures. This study identifies and analyzes particular issues inherent to China’s environmental regulatory policies and measures regarding the paper industry and proposed policy suggestions for improving the environmental regulation of China’s paper industry.

The paper-disc soil method is a soil algal bioassay used to assess soil water transfer in polluted soils. Although this ecotoxicological method was first established in 2016 to assess soil pollution, quantitative toxicity assessments of Cu- or Ni-treated soil and in situ or ex situ soils polluted with other heavy metals (HMs) have not been widely conducted. In this study, the paper-disc soil method was validated under different test conditions. The validated paper-disc soil method was used to quantitatively investigate the toxicity of four HMs (As, Cd, Cr, and Zn). Based on the results, the test species, initial inoculation concentration in the algal-dispersed solution, water content, light intensity, and exposure duration were proposed as Chlorococcum infusionum, 3 × 10