1. Clinical review: Practical recommendations on the management of perioperative heart failure in cardiac surgery
- Author
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Mebazaa, A, Pitsis, AA, Rudiger, A, Toller, W, Longrois, D, Ricksten, SE, Bobek, I, De Hert, S, Wieselthaler, G, Schirmer, U, von Segesser, LK, Sander, M, Poldermans, D, Ranucci, M, Karpati, PCJ, Wouters, P, Seeberger, M, Schmid, ER, Weder, W, Follath, F, Mebazaa, A, Pitsis, AA, Rudiger, A, Toller, W, Longrois, D, Ricksten, SE, Bobek, I, De Hert, S, Wieselthaler, G, Schirmer, U, von Segesser, LK, Sander, M, Poldermans, D, Ranucci, M, Karpati, PCJ, Wouters, P, Seeberger, M, Schmid, ER, Weder, W, and Follath, F
- Abstract
Acute cardiovascular dysfunction occurs perioperatively in more than 20% of cardiosurgical patients, yet current acute heart failure (HF) classification is not applicable to this period. Indicators of major perioperative risk include unstable coronary syndromes, decompensated HF, signifi cant arrhythmias and valvular disease. Clinical risk factors include history of heart disease, compensated HF, cerebrovascular disease, presence of diabetes mellitus, renal insufficiency and high-risk surgery. EuroSCORE reliably predicts perioperative cardiovascular alteration in patients aged less than 80 years. Preoperative B-type natriuretic peptide level is an additional risk stratification factor. Aggressively preserving heart function during cardiosurgery is a major goal. Volatile anaesthetics and levosimendan seem to be promising cardioprotective agents, but large trials are still needed to assess the best cardioprotective agent(s) and optimal protocol(s). The aim of monitoring is early detection and assessment of mechanisms of perioperative cardiovascular dysfunction. Ideally, volume status should be assessed by 'dynamic' measurement of haemodynamic para meters. Assess heart function first by echocardiography, then using a pulmonary artery catheter (especially in right heart dysfunction). If volaemia and heart function are in the normal range, cardiovascular dysfunction is very likely related to vascular dysfunction. In treating myocardial dysfunction, consider the following options, either alone or in combination: low-to-moderate doses of dobutamine and epinephrine, milrinone or levosimendan. In vasoplegia-induced hypotension, use norepinephrine to maintain adequate perfusion pressure. Exclude hypovolaemia in patients under vasopressors, through repeated volume assessments. Optimal perioperative use of inotropes/vasopressors in cardiosurgery remains controversial, and further large multinational studies are needed. Cardiosurgical perioperative classification of cardiac impa
- Published
- 2010