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6 results on '"d'Abramo C"'

1. SAFE AND SUSTAINABLE NANO-ENABLED ANTIMICROBIALS TO REDUCE THE PRESENCE OF CONTAMINANTS OF EMERGING CONCERN IN THE AQUATIC ENVIRONMENTS: AN INTEGRATION PERSPECTIVE

Author

Negrini, B, D’Abramo, C, Bonfanti, P, Colombo, A, Floris, P, Perucca, M, Costamagna, M, Seyed Aldaghi, A, Mantecca, P, Beatrice Negrini, Christian D’Abramo, Patrizia Bonfanti, Anita Colombo, Pamela Floris, Massimo Perucca, Mattia Costamagna, Ahmad Seyed Aldaghi, Paride Mantecca, Negrini, B, D’Abramo, C, Bonfanti, P, Colombo, A, Floris, P, Perucca, M, Costamagna, M, Seyed Aldaghi, A, Mantecca, P, Beatrice Negrini, Christian D’Abramo, Patrizia Bonfanti, Anita Colombo, Pamela Floris, Massimo Perucca, Mattia Costamagna, Ahmad Seyed Aldaghi, and Paride Mantecca

Published
2024

2. Exploiting Zebrafish Tools for a Safe and Sustainable Development of Nano-Enabled Antimicrobials to Reduce the Presence of Antimicrobial-Resistant Bacteria in the Aquatic Environments

Author

Negrini, B, D'Abramo, C, Bonfanti, P, Colombo, A, Costamagna, M, Aldaghi Seyed, A, Perucca, M, Mantecca, P, Negrini Beatrice, D’Abramo Christian, Bonfanti Patrizia, Colombo Anita, Costamagna Mattia, Aldaghi Seyed Ahmad, Perucca Massimo, Mantecca Paride, Negrini, B, D'Abramo, C, Bonfanti, P, Colombo, A, Costamagna, M, Aldaghi Seyed, A, Perucca, M, Mantecca, P, Negrini Beatrice, D’Abramo Christian, Bonfanti Patrizia, Colombo Anita, Costamagna Mattia, Aldaghi Seyed Ahmad, Perucca Massimo, and Mantecca Paride

Published
2024

3. EXPLOITING ZEBRAFISH TOOLS TO EVALUATE BIOINTERACTIONS AND ADVERSE EFFECTS OF SILICA- AND COPPER-BASED NANOMATERIALS

Author

D’Abramo, C, Negrini, B, Mazzotta, R, Floris, P, Bonfanti, P, Colombo, A, Bragato, C, Mantecca, P, D’Abramo, Christian, Mazzotta, Roberta., Floris, Pamela, Bonfanti, Patrizia, Colombo, Anita, Bragato, Cinzia, Mantecca, P., D’Abramo, C, Negrini, B, Mazzotta, R, Floris, P, Bonfanti, P, Colombo, A, Bragato, C, Mantecca, P, D’Abramo, Christian, Mazzotta, Roberta., Floris, Pamela, Bonfanti, Patrizia, Colombo, Anita, Bragato, Cinzia, and Mantecca, P.

Published
2023

4. On the In Vitro and In Vivo Hazard Assessment of a Novel Nanomaterial to Reduce the Use of Zinc Oxide in the Rubber Vulcanization Process

Author

Bragato, C, Mostoni, S, D’Abramo, C, Gualtieri, M, Pomilla, F, Scotti, R, Mantecca, P, Bragato, Cinzia, Mostoni, Silvia, D’Abramo, Christian, Gualtieri, Maurizio, Pomilla, Francesca Rita, Scotti, Roberto, Mantecca, Paride, Bragato, C, Mostoni, S, D’Abramo, C, Gualtieri, M, Pomilla, F, Scotti, R, Mantecca, P, Bragato, Cinzia, Mostoni, Silvia, D’Abramo, Christian, Gualtieri, Maurizio, Pomilla, Francesca Rita, Scotti, Roberto, and Mantecca, Paride

Abstract

Zinc oxide (ZnO) is the most efficient curing activator employed in the industrial rubber production. However, ZnO and Zn(II) ions are largely recognized as an environmental hazard being toxic to aquatic organisms, especially considering Zn(II) release during tire lifecycle. In this context, aiming at reducing the amount of microcrystalline ZnO, a novel activator was recently synthetized, constituted by ZnO nanoparticles (NPs) anchored to silica NPs (ZnO-NP@SiO2-NP). The objective of this work is to define the possible hazards deriving from the use of ZnO-NP@SiO2-NP compared to ZnO and SiO2 NPs traditionally used in the tire industry. The safety of the novel activators was assessed by in vitro testing, using human lung epithelial (A549) and immune (THP-1) cells, and by the in vivo model zebrafish (Danio rerio). The novel manufactured nanomaterial was characterized morphologically and structurally, and its effects evaluated in vitro by the measurement of the cell viability and the release of inflammatory mediators, while in vivo by the Fish Embryo Acute Toxicity (FET) test. Resulting data demonstrated that ZnO-NP@SiO2-NP, despite presenting some subtoxic events, exhibits the lack of acute effects both in vitro and in vivo, supporting the safe-by-design development of this novel material for the rubber industry.

Published
2022

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