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48 results on '"Watkins D.N."'

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1. ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer.

2. Deep multi-region whole-genome sequencing reveals heterogeneity and gene-by-environment interactions in treatment-naive, metastatic lung cancer.

3. ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer.

4. In vivo evidence that RBM5 is a tumour suppressor in the lung.

5. Deep multi-region whole-genome sequencing reveals heterogeneity and gene-by-environment interactions in treatment-naive, metastatic lung cancer.

6. The role of canonical and non-canonical Hedgehog signaling in tumor progression in a mouse model of small cell lung cancer.

7. Blockade of the IL-6 trans-signalling/STAT3 axis suppresses cachexia in Kras-induced lung adenocarcinoma.

8. Targeted catalytic inhibition of EZH2 synergizes with low-dose HDACi in malignant rhabdoid tumors.

9. The role of canonical and non-canonical Hedgehog signaling in tumor progression in a mouse model of small cell lung cancer.

10. Blockade of the IL-6 trans-signalling/STAT3 axis suppresses cachexia in Kras-induced lung adenocarcinoma.

11. Targeted catalytic inhibition of EZH2 synergizes with low-dose HDACi in malignant rhabdoid tumors.

12. Low-dose histone deacetylase inhibitor treatment leads to tumor growth arrest and multi-lineage differentiation of malignant rhabdoid tumors.

13. Low-dose histone deacetylase inhibitor treatment leads to tumor growth arrest and multi-lineage differentiation of malignant rhabdoid tumors.

14. Changes in aldehyde dehydrogenase-1 expression during neoadjuvant chemotherapy predict outcome in locally advanced breast cancer.

15. Mitochondria-derived reactive oxygen species drive GANT61-induced mesothelioma cell apoptosis

16. TP 227b Induction of mesothelioma cell apoptosis by GANT61, a small molecule inhibitor of GLI transcription factors: Evidence for redox-driven cytotoxicity

17. The evolution of therapies in non-small cell lung cancer.

18. Changes in aldehyde dehydrogenase-1 expression during neoadjuvant chemotherapy predict outcome in locally advanced breast cancer.

19. TP 227b Induction of mesothelioma cell apoptosis by GANT61, a small molecule inhibitor of GLI transcription factors: Evidence for redox-driven cytotoxicity

20. Mitochondria-derived reactive oxygen species drive GANT61-induced mesothelioma cell apoptosis

21. A phase IIA study of ha-irinotecan, a cd44-targeted formulation of hyaluronic acid and irinotecan, in the treatment of extensive stage small cell lung cancer and its effect on cancer stem-like cells.

22. Development of small cell lung cancer primary xenografts using specimens obtained by endobronchial-ultrasound transbronchial needle aspiration: A novel pre-clinical model.

23. Seminoma and embryonal carcinoma footprints identified by analysis of integrated genome-wide epigenetic and expression profiles of germ cell cancer cell lines

24. A phase IIA study of ha-irinotecan, a cd44-targeted formulation of hyaluronic acid and irinotecan, in the treatment of extensive stage small cell lung cancer and its effect on cancer stem-like cells.

25. Development of small cell lung cancer primary xenografts using specimens obtained by endobronchial-ultrasound transbronchial needle aspiration: A novel pre-clinical model.

26. Low dose histone deacetylase inhibitor treatment halts rhabdoid tumour growth and induces osteogenesis and neuronal differentiation.

27. Visualizing renal primary cilia.

28. Cancer stem cells in lung cancer: Evidence and controversies.

29. Deregulated GP130 signalling contributes to initiation of tumours and cancer-related cachexia in murine models.

30. The prognostic significance of aldehyde dehydrogenase 1A1 (ALDH1A1) and CD133 expression in early stage non-small cell lung cancer.

31. Novel therapeutic targets in non-small cell lung cancer.

33. Mutational Analysis of Hedgehog Signaling Pathway Genes in Human Malignant Mesothelioma

34. Visualizing renal primary cilia.

35. Cancer stem cells in lung cancer: Evidence and controversies.

36. The prognostic significance of aldehyde dehydrogenase 1A1 (ALDH1A1) and CD133 expression in early stage non-small cell lung cancer.

37. Novel therapeutic targets in non-small cell lung cancer.

38. Deregulated GP130 signalling contributes to initiation of tumours and cancer-related cachexia in murine models.

40. Mutational Analysis of Hedgehog Signaling Pathway Genes in Human Malignant Mesothelioma

41. Development of primary xenografts using lung cancer specimens obtained by endobronchial ultrasound-guided transbronchial needle aspiration.

42. Enhanced efficacy of local etoposide delivery by poly(ether-anhydride) particles against small cell lung cancer in vivo.

43. Just say no to ATOH: How HIC1 methylation might predispose medulloblastoma to lineage addiction.

44. Enhanced efficacy of local etoposide delivery by poly(ether-anhydride) particles against small cell lung cancer in vivo.

45. Development of primary xenografts using lung cancer specimens obtained by endobronchial ultrasound-guided transbronchial needle aspiration.

46. Just say no to ATOH: How HIC1 methylation might predispose medulloblastoma to lineage addiction.

47. Pentastatin-1, a collagen IV derived 20-mer peptide, suppresses tumor growth in a small cell lung cancer xenograft model.

48. Pentastatin-1, a collagen IV derived 20-mer peptide, suppresses tumor growth in a small cell lung cancer xenograft model.

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