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Homeira Vafaei,1 Shohreh Roozmeh,1 Kamran Hessami,1,2 Maryam Kasraeian,1 Nasrin Asadi,1 Azam Faraji,1 Khadije Bazrafshan,1 Najmieh Saadati,3 Soudabeh Kazemi Aski,4 Elahe Zarean,5 Mahboobeh Golshahi,6 Mansoureh Haghiri,7 Nazanin Abdi,8 Reza Tabrizi,9 Bahram Heshmati,10 Elham Arshadi11 1Maternal-Fetal Medicine Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; 2Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran; 3Fertility Infertility and Perinatology Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; 4Department of Obstetrics & Gynecology, Reproductive Health Research Center, Guilan University of Medical Sciences, Rasht, Iran; 5Department of Obstetrics and Gynecology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran; 6Department of Psychology, University of Guilan, Rasht, Iran; 7Department of Perinatology, Maternal-Fetal Center, Vali-e-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran; 8Fertility and Infertility Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran; 9Health Policy Research Center, Institute of Health, Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran; 10Medical Journalism Department, Paramedical School, Shiraz University of Medical Sciences, Shiraz, Iran; 11Department of Obstetrics and Gynecology, Shiraz University of Medical Sciences, Shiraz, IranCorrespondence: Nasrin AsadiMaternal-Fetal Medicine Research Center, Shiraz University of Medical Sciences, Maternal- Fetal Medicine (Perinatology), Hafez Hospital, Chamran Ave, Shiraz, IranTel +98-71-36128257Fax +98-71-362128257Email nasadi2012@yahoo.caBackground: The coronavirus disease of 2019 (COVID-19) pandemic has become the most challenging issue for healthcare organizations and governments all over the world. The lack of evidence-based data on the management of COVID-19 infection during pregnancy causes an additional stres

Kamran Hessami,1,2 Maryam Kasraeian,2 Nasrin Asadi,2 Homeira Vafaei,2 Leila Foroughinia3 1Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran; 2Maternal-Fetal Medicine Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; 3Eastern Health, Box Hill Hospital, FRANZCOG, Box Hill, Victoria, AustraliaCorrespondence: Kamran HessamiMaternal-Fetal Medicine (Perinatology) Research Center, Hafez Hospital, Chamran Ave, Shiraz, IranTel +98-71-36128257Fax +98-71-362128257Email hessamikamran@gmail.comPurpose: There is a growing evidence suggesting that hypertensive disorders of pregnancy (HDP), especially preeclampsia, are associated with an increased risk of cardiometabolic disease for both mother and child later in life. The objective of this study was to determine the association of maternal and umbilical cord blood (UCB) lipid profiles with uterine and fetal-placental blood flow at the third trimester of pregnancy.Patients and Methods: A total of  1,135 women were prospectively followed through pregnancy and data for 812 mother-newborn pairs, including 170 HDP ‎developed subjects and ‎ 642 ‎normotensive subjects were analyzed at the end of the study. Maternal serum and UCB triglyceride (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and non-HDL-C levels were compared between HDP and normotensive groups; moreover, the association between lipid parameters and abnormal pulsatility indices (PIs) of uterine (UtA), umbilical (UA), and middle cerebral (MCA) arteries was evaluated with multivariate regression analysis models. The same analyses were carried out on subgroups of HDP (preeclampsia vs gestational hypertension).Results: The mean TG, TC, LDL-C, and non-HDL-C levels were significantly higher in mother-newborn pairs of the HDP group compared to the normotensive group. In the HDP group, maternal TG and

Saeedeh Foroughinia,1 Kamran Hessami,2,3 Nasrin Asadi,3 Leila Foroughinia,4 Mohammadjavad Hadianfard,5 Azadeh Hajihosseini,5 Najmeh Pirasteh,5 Mehrdad Vossoughi,6 Homeira Vafaei,3 Azam Faraji,3 Maryam Kasraeian,3 Mehrnoosh Doroudchi,7 Mohammad Rafiee Monjezi,8 Shohreh Roozmeh,3 Khadije Bazrafshan3 1Obstetrics and Gynecology Department, Shiraz University of Medical Sciences, Shiraz, Iran; 2Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran; 3Maternal-Fetal Medicine Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; 4Box Hill Hospital, FRANZCOG, Eastern Health, Victoria, Australia; 5Physical Medicine and Rehabilitation Department, Shiraz University of Medical Sciences, Shiraz, Iran; 6Oral and Dental Disease Research Center, Department of Dental Public Health, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran; 7Department of Immunology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran; 8Shiraz Institute for Cancer Research, Shiraz University of Medical Sciences, Shiraz, IranCorrespondence: Nasrin AsadiMaternal-Fetal Medicine Research Center, Shiraz University of Medical Sciences, Shiraz, IranTel +98-71-36128257Fax +98-71-362128257Email nasadi2012@yahoo.caObjective: The aim of the current study is to evaluate the efficacy and safety of acupuncture on sleep quality and overnight melatonin secretion, measured as urinary 6-sulfatoxymelatonin, in pregnant women.Patients and Methods: This randomized, parallel, single-blinded (participant), controlled trial was conducted on 72 pregnant women with insomnia. Study participants were randomly assigned to either the intervention, 10 sessions of acupuncture treatment over a 3-week period, or control group by block randomization (1:1). Patients in both groups were evaluated at baseline and post-treatment (third week) using the Pittsburgh Sleep Quality Index (PSQI) score (as the primary outcome) and urinary 6-sulfatoxymelatonin.Results: Fift