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[Italiano]: Il volume, che raccoglie gli atti di un seminario svoltosi nel mese di ottobre del 2022 presso il DSU dell’Università degli Studi di Napoli Federico II, si propone di offrire un contributo su un tema essenziale della ricerca storico-intellettuale alle origini dell’età moderna, ossia i rapporti fra profezia e politica. Dal saggio sulla figura del profeta nel pensiero di Max Weber, che assume il ruolo di una ouverture metodologica, e da Savonarola a Machiavelli a Guicciardini a Bodin ai libertini a Campanella, viene presentata una serie di contributi su autori, che in modo profondo e peculiare avevano affrontato le relazioni fra la profezia e la politica in epoca di grandi rivolgimenti e innovazioni. /[English]: The volume, which collects the proceedings of a seminar held in October 2022 at the DSU of the University of Naples Federico II, aims to offer a contribution on an essential theme of historical-intellectual research at the origins of modern age, namely the relationships between prophecy and politics. From the essay on the figure of the prophet in the thought of Max Weber, which takes on the role of a methodological overture, and from Savonarola to Machiavelli, Guicciardini, Bodin, the Libertines, Campanella, what is diplayed is a series of contributions on authors who, in a deep and peculiar way, faced the relationships between prophecy and politics in an era of great upheavals and innovations.

Publisher: FedOA - Federico II University Press Series: Clio. Essays in History, Archaeology and Art History Pages: 224 Language: Italian NBN: http://nbn.depositolegale.it/resolver.pl?nbn=urn:nbn:it:unina-29790 Abstract: The volume, which collects the proceedings of a seminar held in October 2022 at the DSU of the University of Naples Federico II, aims to offer a contribution on an essential theme of historical-intellectual research at the origins of modern age, namely the relationships between prophecy and politics. From the essay on the figure of the prophet in the thought of Max Weber, which takes on the role of a methodological overture, and from Savonarola to Machiavelli, Guicciardini, Bodin, the Libertines, Campanella, what is diplayed is a series of contributions on authors who, in a deep and peculiar way, faced the relationships between prophecy and politics in an era of great upheavals and innovations., Editore: FedOA - Federico II University Press Serie: Clio. Saggi di scienze storiche, archeologiche e storico-artistiche Pagine: 224 Lingua: Italiano NBN: http://nbn.depositolegale.it/resolver.pl?nbn=urn:nbn:it:unina-29790 Abstract: Il volume, che raccoglie gli atti di un seminario svoltosi nel mese di ottobre del 2022 presso il DSU dell’Università degli Studi di Napoli Federico II, si propone di offrire un contributo su un tema essenziale della ricerca storico-intellettuale alle origini dell’età moderna, ossia i rapporti fra profezia e politica. Dal saggio sulla figura del profeta nel pensiero di Max Weber, che assume il ruolo di una ouverture metodologica, e da Savonarola a Machiavelli a Guicciardini a Bodin ai libertini a Campanella, viene presentata una serie di contributi su autori, che in modo profondo e peculiare avevano affrontato le relazioni fra la profezia e la politica in epoca di grandi rivolgimenti e innovazioni.

Esta obra es una serie de monografías que reconstruyen la historia de la vegetación pretérita de la Península Ibérica e islas Baleares mediante la recopilación exhaustiva y síntesis de los principales registros paleobotánicos publicados para estos territorios, abarcando un marco temporal de unos 66 millones de años que se extiende desde el presente a los inicios del período Paleoceno. Para cada uno de ellos se describe el estado actual de su entorno, anotando sus características fisiográficas, climáticas, florísticas y de la vegetación. A esta información siguen los datos paleobotánicos disponibles, ya sea a través de tablas de diagramas de polen y esporas de los grupos vegetales más representados, de restos antracológicos, carpológicos, de fitolitos y otros restos vegetales, así como de información cronológica precisa para su ubicación temporal. Los resultados se exponen con abundancia de tablas, ilustraciones, fotografías, estratigrafías y diagramas sintéticos que hacen el contenido fácilmente asequible a todos los investigadores interesados en el conocimiento de los vegetales, cualquiera que sea su formación y especialidad. Esta obra pretende ayudar a entender los cambios sufridos por la vegetación en el pasado, lo que nos permitirá entender mejor cuáles serán las claves de sus cambios futuros, en un contexto de cambio global como el que vivimos en la actualidad. El volumen III (Holocene) recoge los datos del periodo comprendido entre el presente y los aproximadamente 12000 años antes del presente.

The Central Balkans are a key biogeographical region in Southern Europe, influenced by a central European-Mediterranean climate, which acted as a refugium for flora and fauna, and favored the dispersion of Neanderthals and migration of modern human populations during Late Glacial Period. This study presents pollen analyses of sediment and hyaena coprolites from Pešturina Cave in Serbia to reconstruct the vegetation landscapes faced by Balkan Neanderthals and early Anatomically Modern Humans between MIS 5e-3. Between MIS 5e-5c (archaeological layers 4c and 4b) and MIS 5b-5a (layer 4a), semi-forested environments prevailed, characterized by Pinus, deciduous Quercus, Tilia and other angiosperm woody taxa, accompanied by heliophytes such as Artemisia and Poaceae. During MIS 4-3 (layers 3-2), the vegetation was dominated by Artemisia-Poaceae steppes with Quercus patches, conifers and legumes. Overall across the sequence, pollen assemblages are highly diverse and include a number of deciduous trees and sclerophylls. In addition, the occurrence of several herbaceous taxa reinforces the view that the Balkans were outstanding for endemicity. Neanderthals and early Upper Palaeolithic hominins lived in a highly diverse refugium, offering multiple opportunities for survival during the warm interstadials and, more critically, the cold stadials of the Pleistocene.

Esta obra es una serie de monografías que reconstruyen la historia de la vegetación pretérita de la Península Ibérica e islas Baleares mediante la recopilación exhaustiva y síntesis de los principales registros paleobotánicos publicados para estos territorios, abarcando un marco temporal de unos 66 millones de años que se extiende desde el presente a los inicios del período Paleoceno. Para cada uno de ellos se describe el estado actual de su entorno, anotando sus características fisiográficas, climáticas, florísticas y de la vegetación. A esta información siguen los datos paleobotánicos disponibles, ya sea a través de tablas de diagramas de polen y esporas de los grupos vegetales más representados, de restos antracológicos, carpológicos, de fitolitos y otros restos vegetales, así como de información cronológica precisa para su ubicación temporal. Los resultados se exponen con abundancia de tablas, ilustraciones, fotografías, estratigrafías y diagramas sintéticos que hacen el contenido fácilmente asequible a todos los investigadores interesados en el conocimiento de los vegetales, cualquiera que sea su formación y especialidad. Esta obra pretende ayudar a entender los cambios sufridos por la vegetación en el pasado, lo que nos permitirá entender mejor cuáles serán las claves de sus cambios futuros, en un contexto de cambio global como el que vivimos en la actualidad. El volumen II (Pleistocene) recoge los datos del periodo comprendido entre los aproximadamente 12 000 años y los 2.59 millones de años antes del presente.

Esta obra es una serie de monografías que reconstruyen la historia de la vegetación pretérita de la Península Ibérica e islas Baleares mediante la recopilación exhaustiva y síntesis de los principales registros paleobotánicos publicados para estos territorios, abarcando un marco temporal de unos 66 millones de años que se extiende desde el presente a los inicios del período Paleoceno. Para cada uno de ellos se describe el estado actual de su entorno, anotando sus características fisiográficas, climáticas, florísticas y de la vegetación. A esta información siguen los datos paleobotánicos disponibles, ya sea a través de tablas de diagramas de polen y esporas de los grupos vegetales más representados, de restos antracológicos, carpológicos, de fitolitos y otros restos vegetales, así como de información cronológica precisa para su ubicación temporal. Los resultados se exponen con abundancia de tablas, ilustraciones, fotografías, estratigrafías y diagramas sintéticos que hacen el contenido fácilmente asequible a todos los investigadores interesados en el conocimiento de los vegetales, cualquiera que sea su formación y especialidad. Esta obra pretende ayudar a entender los cambios sufridos por la vegetación en el pasado, lo que nos permitirá entender mejor cuáles serán las claves de sus cambios futuros, en un contexto de cambio global como el que vivimos en la actualidad. El volumen I (Paleocene – Pliocene) recoge los datos del periodo comprendido entre los 2.59 y los 66 millones de años antes del presente.

In mobile app development, cross-platform approaches have emerged as an alternative to maintaining separate codebases for each target platform. A number of different cross-platform frameworks are available, which allow developers to build a single app targeting multiple platforms. A less used approach is the progressive web app, a type of web app which is installable and available offline. Progressive web apps achieve cross-platform support by running in the browser, but they appear like regular apps to the user. When building a cross-platform app, stakeholders may face the decision between using a cross-platform framework or developing a progressive web app. This study aims to compare the differences in user experience between cross-platform framework apps and progressive web apps, by comparing performance and evaluating functional and visual differences. Specifically, launch time, battery usage, app size, and feature load times were measured, and the appearance and functionality of the camera, sharing, notifications and authentication features was evaluated. To achieve this, two apps were developed: one progressive web app using React, and one cross-platform framework app using React Native, both containing the same functionality. The performance, appearance and functionality of these apps was evaluated on Android and iOS. The results indicate that on lower end phones, React Native apps generally outperform progressive web apps, and their appearance and functionality is also more native-like. However, the differences are often small, and progressive web apps can be a valid alternative for cross-platform development., Inom mobilapputveckling har plattformsoberoende utveckling blivit ett alternativ till att underhålla en separat kodbas för varje platform där appen ska vara tillgänglig. Ett antal olika multiplattformsramverk finns tillgängliga, vilka tillåter utvecklingen av en app för flera olika plattformar. En mindre vanlig metod är progressive webbappar, en typ av webbappar som kan installeras och är tillgängliga offline. Progressiva webbappar är plattformsoberoende eftersom de körs i webbläsaren, men de ser ut som vanliga appar för användaren. Under utvecklingen av plattformsoberoende appar kan ett val mellan att använda ett multiplattformsramverk eller utveckla en progressiv webbapp bli aktuellt. Denna studie syftar till att jämföra skillnader i användarupplevelsen mellan multiplattformsramverksappar och progressiva webbappar, genom att jämföra prestanda och evaluera utseende och funktionalitet. Starttid, batterianvändning, appstorlek och funktioners laddningstid mättes, och utseende och funktionalitet av kamera-, delnings-, notis-, och autentiseringsfunktioner utvärderades. För att uppnå detta utvecklades två appar: en progressiv webbapp med React, och en app med multiplattformsramverket React Native, båda med samma funktionalitet. Prestandan, utseendet och funktionaliteten av apparna utvärderades sedan på Android och iOS. Resultatet indikerar att React Native-appar generellt presterar bättre än progressiva webbappar på telefoner med lägre prestanda. Utseendet och funktionaliteten i React Native-appar är också mer likt operativsystemets egna funktionaliteter. Skillnaderna är däremot oftast små, och progressiva webbappar kan utgöra ett godtagbart alternativ för platformsoberoende utveckling.

In mobile app development, cross-platform approaches have emerged as an alternative to maintaining separate codebases for each target platform. A number of different cross-platform frameworks are available, which allow developers to build a single app targeting multiple platforms. A less used approach is the progressive web app, a type of web app which is installable and available offline. Progressive web apps achieve cross-platform support by running in the browser, but they appear like regular apps to the user. When building a cross-platform app, stakeholders may face the decision between using a cross-platform framework or developing a progressive web app. This study aims to compare the differences in user experience between cross-platform framework apps and progressive web apps, by comparing performance and evaluating functional and visual differences. Specifically, launch time, battery usage, app size, and feature load times were measured, and the appearance and functionality of the camera, sharing, notifications and authentication features was evaluated. To achieve this, two apps were developed: one progressive web app using React, and one cross-platform framework app using React Native, both containing the same functionality. The performance, appearance and functionality of these apps was evaluated on Android and iOS. The results indicate that on lower end phones, React Native apps generally outperform progressive web apps, and their appearance and functionality is also more native-like. However, the differences are often small, and progressive web apps can be a valid alternative for cross-platform development., Inom mobilapputveckling har plattformsoberoende utveckling blivit ett alternativ till att underhålla en separat kodbas för varje platform där appen ska vara tillgänglig. Ett antal olika multiplattformsramverk finns tillgängliga, vilka tillåter utvecklingen av en app för flera olika plattformar. En mindre vanlig metod är progressive webbappar, en typ av webbappar som kan installeras och är tillgängliga offline. Progressiva webbappar är plattformsoberoende eftersom de körs i webbläsaren, men de ser ut som vanliga appar för användaren. Under utvecklingen av plattformsoberoende appar kan ett val mellan att använda ett multiplattformsramverk eller utveckla en progressiv webbapp bli aktuellt. Denna studie syftar till att jämföra skillnader i användarupplevelsen mellan multiplattformsramverksappar och progressiva webbappar, genom att jämföra prestanda och evaluera utseende och funktionalitet. Starttid, batterianvändning, appstorlek och funktioners laddningstid mättes, och utseende och funktionalitet av kamera-, delnings-, notis-, och autentiseringsfunktioner utvärderades. För att uppnå detta utvecklades två appar: en progressiv webbapp med React, och en app med multiplattformsramverket React Native, båda med samma funktionalitet. Prestandan, utseendet och funktionaliteten av apparna utvärderades sedan på Android och iOS. Resultatet indikerar att React Native-appar generellt presterar bättre än progressiva webbappar på telefoner med lägre prestanda. Utseendet och funktionaliteten i React Native-appar är också mer likt operativsystemets egna funktionaliteter. Skillnaderna är däremot oftast små, och progressiva webbappar kan utgöra ett godtagbart alternativ för platformsoberoende utveckling.

[Italiano]: Il volume, che raccoglie gli atti di un seminario svoltosi nel mese di ottobre del 2022 presso il DSU dell’Università degli Studi di Napoli Federico II, si propone di offrire un contributo su un tema essenziale della ricerca storico-intellettuale alle origini dell’età moderna, ossia i rapporti fra profezia e politica. Dal saggio sulla figura del profeta nel pensiero di Max Weber, che assume il ruolo di una ouverture metodologica, e da Savonarola a Machiavelli a Guicciardini a Bodin ai libertini a Campanella, viene presentata una serie di contributi su autori, che in modo profondo e peculiare avevano affrontato le relazioni fra la profezia e la politica in epoca di grandi rivolgimenti e innovazioni. /[English]: The volume, which collects the proceedings of a seminar held in October 2022 at the DSU of the University of Naples Federico II, aims to offer a contribution on an essential theme of historical-intellectual research at the origins of modern age, namely the relationships between prophecy and politics. From the essay on the figure of the prophet in the thought of Max Weber, which takes on the role of a methodological overture, and from Savonarola to Machiavelli, Guicciardini, Bodin, the Libertines, Campanella, what is diplayed is a series of contributions on authors who, in a deep and peculiar way, faced the relationships between prophecy and politics in an era of great upheavals and innovations.

Esta tesis, Ley estatal de servicios sociales: de las aspiraciones a las propuestas. Una visión desde el ámbito profesional, nace de varias inquietudes relacionadas con mi ejercicio profesional en el sistema público de servicios sociales. También por mi acercamiento a la regulación de los servicios sociales desde mi doble interés por el derecho y el trabajo social, y por participar activamente en la creación y aprobación de varias leyes regionales sobre servicios sociales Como ha sido ampliamente estudiado, la aprobación de la Constitución española de1978 permitió dejar atrás el modelo de beneficencia para adentrarse en una senda de derechos en la que el sistema público de servicios sociales se perfilaba como el cuarto pilaren el Estado de Bienestar. Desde sectores mayoritarios de los ámbitos académico, institucional y profesional, especialmente del trabajo social, se plantea la necesidad de disponer de una ley estatal de servicios sociales. Es esta una aspiración que se ha mantenido constante a lo largo de las últimas décadas..., This thesis entitled as “Social Services State Law: From aspirations to bills. A viewfrom the professional scope” is born from several concerns are related to my professionalpractice within the Public System of Social Services. It also comes from my experiencehaving a close role in the regulation of social services which arises from my interest in lawand social work, and for actively participate in the creation and passing of several regionallaws on social servicesAs it has been thoroughly studied, the adoption of the Spanish Constitution of 1978allowed it to turn the page on the charity model and led to a path made of rights in which thePublic System of Social Services emerged as the fourth pillar of the Welfare State. Maingroups from the academic, institutional, and professional field, and particularly from socialwork, are taking into consideration the need of having a State law on social services. This isan aspiration which has been a constant during the last decades...

Publisher: FedOA - Federico II University Press Series: Clio. Essays in History, Archaeology and Art History Pages: 224 Language: Italian NBN: http://nbn.depositolegale.it/resolver.pl?nbn=urn:nbn:it:unina-29790 Abstract: The volume, which collects the proceedings of a seminar held in October 2022 at the DSU of the University of Naples Federico II, aims to offer a contribution on an essential theme of historical-intellectual research at the origins of modern age, namely the relationships between prophecy and politics. From the essay on the figure of the prophet in the thought of Max Weber, which takes on the role of a methodological overture, and from Savonarola to Machiavelli, Guicciardini, Bodin, the Libertines, Campanella, what is diplayed is a series of contributions on authors who, in a deep and peculiar way, faced the relationships between prophecy and politics in an era of great upheavals and innovations., Editore: FedOA - Federico II University Press Serie: Clio. Saggi di scienze storiche, archeologiche e storico-artistiche Pagine: 224 Lingua: Italiano NBN: http://nbn.depositolegale.it/resolver.pl?nbn=urn:nbn:it:unina-29790 Abstract: Il volume, che raccoglie gli atti di un seminario svoltosi nel mese di ottobre del 2022 presso il DSU dell’Università degli Studi di Napoli Federico II, si propone di offrire un contributo su un tema essenziale della ricerca storico-intellettuale alle origini dell’età moderna, ossia i rapporti fra profezia e politica. Dal saggio sulla figura del profeta nel pensiero di Max Weber, che assume il ruolo di una ouverture metodologica, e da Savonarola a Machiavelli a Guicciardini a Bodin ai libertini a Campanella, viene presentata una serie di contributi su autori, che in modo profondo e peculiare avevano affrontato le relazioni fra la profezia e la politica in epoca di grandi rivolgimenti e innovazioni.

[SPA] La cordilleras Béticas jugaron un papel fundamental durante los períodos glaciales del Pleistoceno como refugios de flora y vegetación. Se revisan aquí las evidencias paleobotánicas de los principales yacimientos implicados en la región y sus márgenes. A pesar del sesgo existente en los paleodatos y en la distribución geográfica de los registros, se confirman evidencias de la supervivencia de angiospermas leñosas y sistemas forestales en contextos montañosos. En este sentido, la complejidad fisiográfica y la disponibilidad de agua emergen como características esenciales para la pervivencia de taxones leñosos en zonas de montaña mediterránea. Las evidencias paleobotánicas, fusionadas con otras disciplinas (geobotánica, etnografía y genética), sirven como una herramienta útil para comprender la distribución actual de muchas especies vegetales y contribuye a llevar a cabo planes de conservación y gestión más eficientes., [ENG] The Betic mountains have played a fundamental role during Pleistocene glacial periods as vegetation refugia of temperate and Mediterranean woody species. The palaeobotanical evidences of 35 Pleistocene records in the south of the Iberian Peninsula within the area and on the margins of the Betic system are reviewed. Despite the bias in the data sources and available sites, evidence is provided for the survival of woody angiosperms in mountains. In this sense, the physiographic complexity and water availability emerge as essential characteristics for tree survival. Palaeobotanical evidences merged with other disciplines (geobotany, ethnography and genetics) operate as useful tools in understanding the current distribution of plant species and thus make feasible to improve biological conservation and management plans.

The effective potential obtained by loop expansion is usually not real in the range of field values explored by its minima during a phase transition. We apply the optimized perturbation theory in a fixed gauge to singlet scalar extensions of the Standard Model in order to calculate a one-loop effective potential that is real by construction. We test this computational scheme by comparing such a potential obtained in Landau gauge to that derived based on the Higgs pole mass. We carry out the latter construction by imposing physical renormalization conditions, which yields a potential without residual regularization scale dependence. We use our effective potential to study the parameter dependence of the critical temperatures in a two-step phase transition of the form $(0,0)\to (0,w')\to (v,w)$ that occurs for decreasing temperature in scalar extensions of the SM with two vacuum expectation values $v$ and $w$., Comment: 36 pages, 8 figures; references added, published version

This chapter utilises Game Studies, Animal Studies and Affect Studies approaches to explore how videogame adaptation Jurassic World: Evolution (Frontier 2018) mediates Jurassic World’s (2015) themes of captivity, anxiety and boredom in a time of routinised risk and perpetual crisis management (Bhattacharyya 2015; Beck 1992). Critically, the game has been denigrated as boring and repetitious (Stapleton 2018; Freeman 2018); dinosaurs sleep more than fight; and players balance variables to meet minimum thresholds of dinosaur contentment and their own enjoyment. If the film’s hybrid dinosaur signals the increasing banality of ‘terrible lizards,’ I argue that Evolution explores boredom systemically through simulations of banal park maintenance where the speculative animal might ‘respond’ to the player through shared affects and constraints. As W.J.T. Mitchell asks of the dinosaur’s ambivalent meanings of power and extinction, “Are we to scream or to yawn?” (1998:69). This is not a break with games of exploitation and manipulation of the animal, but rather an articulation of our complicity and enmeshment in loops of captivity that embrace human and animal but neither completely. Unable to see the animal itself, filled with tantalising contradictions and distance, we instead become-bored-with the animal.

El artículo presenta un análisis y evaluación de las contribuciones y oportunidades de las entidades de economía social como motores del cambio social en el ámbito local. La incorporación de la economía social en los órganos de participación institucionalizada en materia de bienestar social permitiría profundizar en los procesos democratizadores y de calidad de las políticas sociales públicas locales. A su vez, se presenta una sistematización, desde la práctica y los estudios empíricos realizados, de las tendencias observadas en la oferta de las políticas de participación en el ámbito municipal en el área de bienestar social y las dimensiones que permiten realizar un análisis e implementación de prácticas participativas orientadas a intensificar la calidad democrática en el ámbito local incorporando activamente la economía social., The paper presents an analysis and assessment of contributions and opportunities for social economy organizations as engines of social change at local level. The incorporation of the social economy in the organs of intitutionalized participation in social welfare would deepen the democratization process and quality of local public social policies. In turn, presents a systematic, from the practical and empirical studies of trends in the supply of political participation at the municipal level in the area of social welfare and dimensions that allow analysis and implementation participatory practices designed to enhance the quality of democracy at the local level actively incorporating social economy., Escuela de Estudios Cooperativos, Fac. de Ciencias Económicas y Empresariales, TRUE, pub

La herramienta, que tiene por nombre EDUREV, ha sido creada para ayudar a los estudiantes de Máster y Doctorado a elaborar sus revisiones sistemáticas, a la vez que se ha desarrollado siguiendo las condiciones propias de los materiales en abierto (accesibilidad, reusabilidad, adaptabilidad y combinación). El presente proyecto de innovación es continuación de dos proyectos consecutivos de Innova-Docencia concedidos en el curso 2020-2021 (nº 280) y en el curso 2021-2022 (nº 286). Por ello, son dos los objetivos generales del proyecto. El primero, desarrollar la fase de síntesis de estudios del recurso educativo EDUREV para que sirva de soporte a estudiantes de Máster y Doctorado de la Facultad de Educación en la realización de sus revisiones sistemáticas. El segundo, validar EDUREV como un recurso educativo en abierto para la elaboración de revisiones sistemática en Educación. Los principales beneficiarios del proyecto serán profesores y estudiantes de Máster y Doctorado de la Facultad de Educación. Los objetivos se alcanzarán a través de dos grandes fases y 15 tareas: Fase 1. Desarrollo de la fase de síntesis de estudios del recurso educativo EDUREV y Fase 2. Validación de EDUREV como recurso educativo en abierto para la elaboración de revisiones sistemáticas en Educación. El principal resultado esperado es la puesta en marcha de la herramienta en situaciones reales para la elaboración de revisiones sistemáticas en la Facultad de Educación de la Universidad Complutense de Madrid.

Aim:To explore hospital nurses' perceptions of working conditions that affect their retention and to identify preconditions for retention across nursing subgroups and informants directly involved in the work that nurses do. Introduction. Understanding why nurses want to stay in their job is essential for hospitals to improve retention and develop policies to combat nursing shortages. Retention barriers are known, but mostly pre-COVID-19 and in specific nursing subgroups, while nursing teams are diverse in life phase, education, and expertise. Materials and Methods:A qualitative study with semistructured focus group interviews with nurses from different hospitals. We held interviews with nursing students and with newly graduated, experienced, specialized, and master-educated nurses. In addition, we held interviews with informants directly involved in the work that nurses do. Results:Three themes concerning the perceptions of working conditions and retention preconditions were identified among subgroups: (1) nurses finding their personal pathway, indicating work that fits individual challenges during the life course and work that matches personal motives and authority and control over professional practice; (2) constructive collaboration within the nursing team and with their manager and physicians; and (3) availability of supportive facilities, e.g., development, professionalization, working environment, and rewards. Conclusion:Elements for retention occur at individual, team, and organizational levels. Nurses find it important that their profession aligns with their personal pathway and are motivated by constructive collaboration in a stimulating team. They emphasized organizational support in realizing career tracks and in active participation in decision-making. These themes are consistent across subgroups and encompass multiple interacting elements. Implications for Nursing Management

Current LoRa networks including those following the LoRaWAN specification use the primitive ALOHA mechanism for media access control due to LoRa's lack of carrier sense capability. From our extensive measurements, the channel activity detection feature that was recently introduced to LoRa for energy-efficiently detecting preamble chirps can also detect payload chirps reliably. This sheds light on an efficient carrier-sense multiple access protocol that we refer to as LMAC for LoRa networks. This article presents the designs of three advancing versions of LMAC that respectively implement carrier-sense multiple access, and balance the communication loads among the channels defined by frequencies and spreading factors based on the end nodes' local information and then additionally the gateway's global information. Experiments on a 50-node lab testbed and a 16-node university deployment show that, compared with ALOHA, LMAC brings up to 2.2× goodput improvement and 2.4× reduction of radio energy per successfully delivered frame. Thus, should LoRaWAN's ALOHA be replaced with LMAC, network performance boosts can be realized. © 2023 Association for Computing Machinery.

The paper analyses the processes of assessment of situations of dependency in Spain and the role of Social Work in them. The study provides new information, trying to detect possible influences of Covid-19 on these processes and analysing existing territorial disparities. From an intentional documentary search, information was subsequently collected from the General Directorates or Sub-directorates, or the autonomous Institutes of social services through an ad hoc questionnaire, obtaining responses from the universe of analysis units (17 autonomous communities). Said information was organized into three categories of analysis: mandatory nature of the social report in the assessment of situations of dependency; place of application of the DAS and the SRS; and professional profiles of the teams for assessing dependency situations. The results show, among other results, the existence of very different interprofessional teams, the application of the scale in divergent contexts, and the different relevance of the social report in the processes. In conclusion, the need to deepen the inclusion of the social report and the professional figure of Social Work in the assessment processes is evident by contributing to the improvement of the coordination of objectives, processes, and resources., El trabajo analiza los procesos de valoración de las situaciones de dependencia en España y el rol del Trabajo Social en los mismos. El estudio aporta información novedosa, tratando de detectar posibles influencias de la Covid-19 en estos procesos y analizando las disparidades territoriales existentes. A partir de una búsqueda documental intencional posteriormente se recogió información de las Direcciones o Subdirecciones Generales o de los Institutos autonómicos de servicios sociales mediante un cuestionario ad hoc, obteniendo respuestas del universo de las unidades de análisis (17 comunidades autónomas). Dicha información se organizó en tres categorías de análisis: preceptividad del informe social en la valoración de las situaciones de dependencia; lugar de aplicación del BVD y de la EVE; y perfiles profesionales de los equipos de valoración de las situaciones de dependencia. Los resultados muestran, entre otros resultados, la existencia de equipos interprofesionales muy diferentes, la aplicación del baremo en contextos divergentes y la distinta relevancia del informe social en los procesos. Como conclusión, se evidencia la necesidad de profundizar en la inclusión del informe social y de la figura profesional del Trabajo Social en los procesos de valoración al contribuir en la mejora de la coordinación de objetivos, procesos y recursos.

The concept of abandonment was researched through the perceptions of people formerly in the foster-care protection system in Spain, focusing the analysis on three crucial moments: the separation of minors from their nuclear family of origin, the duration of their stay in the protection center, and the departure from the center and the protection system. Semi-structured interviews were conducted with eight people who had been in residential foster care for at least two years between 1990 and today. The transcribed stories depict three predominant categories in the life histories of the protagonists: 1) initial (physical) abandonment on the part of the family and entry into the protection center; 2) emotional abandonment during the stay; and 3) institutional abandonment upon exiting the system. The interviewees felt abandoned by their families, but also by the protection system, which devalued them and failed to provide them with sufficient support. The lived experience during their foster care caused a strong, emotional impact that lasted into their adult years. The feeling of abandonment, both on a family and institutional level, is pervasive in the lives of all the interviewees in all moments of their foster care and has not changed since their experiences in 1990 up to the most recent experiences in 2020. Several alternatives to this abandonment feeling by foster-care individuals are proposed, including measures such as reinforcing the figure of professional parenting in residential foster care., Se ha investigado el concepto de abandono a través de la percepción de personas extuteladas del sistema de protección en España, focalizando el análisis de este en tres momentos cruciales: la separación de los menores del núcleo familiar de origen, el período de estancia en el centro de protección, y la salida del centro y del sistema de protección. Se realizaron entrevistas semiestructuradas a ocho personas que estuvieron en acogimiento residencial, al menos dos años, desde 1990 y hasta la actualidad. Transcritos los relatos se plasman a la luz de tres categorías preeminentes en las historias de vida de los protagonistas: 1) el abandono inicial (físico) por parte de la familia y la entrada en el centro de protección; 2) el abandono emocional durante la estancia en el mismo; y 3) el abandono institucional a la salida del sistema. Los entrevistados se han sentido abandonados por sus familias, pero también por el sistema de protección, quien los ha desvalorizado y no les ha prestado suficientes apoyos. La experiencia vivida ha provocado en las personas tuteladas un fuerte impacto emocional que persiste en la edad adulta. Se concluye que, el sentimiento de abandono tanto familiar como institucional está omnipresente en la vida de todos los entrevistados y en toda la secuencia temporal de sus acogimientos, sin que ello se modifique desde las experiencias de 1990 y hasta las últimas de 2020. Se proponen algunas alternativas como medidas de acogimiento residencial o potenciar la figura de la parentalidad profesional.

Proton therapy is a novel radiotherapy technique that exploits the characteristic dose deposition of proton beams through matter to deliver a very localized treatment via radiation. With this technology, the desired radiation dose is given to the tumor, and healthy organs surrounding the tumor can be spared more efficiently than with conventional x-ray radiation therapy. Given that the dose is deposited in a very localized manner, it is important to quantify possible deviations from the treatment plan throughout the whole treatment course (around 30 days). Deviations can occur due to CT imaging inaccuracies, weight loss or gain, changes in the tumor size, or patient position misalignments. In this thesis, proton radiography was investigated as a quality control tool to quantify the existing sources of deviation right before delivering the treatment, and adapt the treatment plan if necessary. Proton radiography is an imaging technique that uses proton radiation to obtain an image of the patient. The advantage of this technique is that the same radiation type is used for treatment and for imaging, providing a direct measurement of the residual proton range. Clinically oriented applications of proton radiography were proposed through simulation and experimental studies, to investigate how proton radiography can detect treatment deviations and trigger plan adaptations. Furthermore, the suitability of two different radiation detectors was investigated for the clinical implementation of proton radiography. The thesis concluded with an analysis of the first proton radiographies acquired for head and neck cancer patients treated with proton therapy.

Identifying a chemical's potential for biotransformation in the aquatic environment is crucial to predict its fate and manage its potential hazards. Due to the complexity of natural water bodies, especially river networks, biotransformation is often studied in laboratory experiments, assuming that study outcomes can be extrapolated to compound behavior in the field. Here, we investigated to what extent outcomes of laboratory simulation studies indeed reflect biotransformation kinetics observed in riverine systems. To determine in-field biotransformation, we measured loads of 27 wastewater treatment plant effluent-borne compounds along the Rhine and its major tributaries during two seasons. Up to 21 compounds were detected at each sampling location. Measured compound loads were used in an inverse model framework of the Rhine river basin to derive k’bio,field values – a compound-specific parameter describing the compounds’ average biotransformation potential during the field studies. To support model calibration, we performed phototransformation and sorption experiments with all the study compounds, identifying 5 compounds that are susceptible towards direct phototransformation and determining Koc values covering four orders of magnitude. On the laboratory side, we used a similar inverse model framework to derive k’bio,lab values from water-sediment experiments run according to a modified OECD 308-type protocol. The comparison of k’bio,lab and k’bio,field revealed that their absolute values differed, pointing towards faster transformation in the Rhine river basin. Yet, we could demonstrate that relative rankings of biotransformation potential and groups of compounds with low, moderate and high persistence agree reasonably well between laboratory and field outcomes. Overall, our results provide evidence that laboratory-based biotransformation studies using the modified OECD 308 protocol and k’bio values derived thereof bear considerable potential to reflect biotransfor

This case study aims to demonstrate how youth philanthropy can be an avenue to democratize philanthropy while it simultaneously benefits young people. We invite readers to explore Youth for Community Improvement, a youth grantmaking program at Greater Worcester Community Foundation, from the vantage points of young people who participate in the program and their adult supporters.

This case study aims to demonstrate how youth philanthropy can be an avenue to democratize philanthropy while it simultaneously benefits young people. We invite readers to explore Youth for Community Improvement, a youth grantmaking program at Greater Worcester Community Foundation, from the vantage points of young people who participate in the program and their adult supporters.

This case study aims to demonstrate how youth philanthropy can be an avenue to democratize philanthropy while it simultaneously benefits young people. We invite readers to explore Youth for Community Improvement, a youth grantmaking program at Greater Worcester Community Foundation, from the vantage points of young people who participate in the program and their adult supporters.

This article aims to delve into the reality of glacial refuges of forests and tree species (including conifers, mesothermophilous angiosperms and xerothermic scrub) during the cold dry phases of the Iberian Pleistocene in which there is evidence of occupation of Middle Palaeolithic people. The research framework focuses on the eastern sector of the Iberian Peninsula due to the physiographic, palaeobotanical and archaeological peculiarities, substantiated by recent studies. We contend that some Neanderthal occupations developed in the context of high geobiological complexity, high biological diversity and highly structured forest ecosystems. We highlight the importance of glacial refuges as local anomalies that, however, would be contingent on vegetational development, and on the survival of Palaeolithic groups in areas with a broad diversity of natural resources.

Questo volume è testimone dell’interesse sviluppatosi negli anni, a cavaliere del secondo e terzo millennio, per il fenomeno della formazione musicale nel corso dei secoli. La ri-fondazione della materia d’indagine, dopo la fase positivistica, è stata sollecitata da una serie di settori d’indagine che ha facilitato la riapertura di un oggetto abbastanza obliato. La curiosità di entrare nei gangli di quelle officine produttrici di musicisti – compositori, strumentisti, cantanti – ha rinnovato gli studi aperti e permesso di apprendere inedite informazioni. Le sollecitazioni più disparate hanno indotto a rimarcare la necessità di sondare fonti dirette e indirette per ragguagliare sempre più questo interessante argomento. Un nugolo di studiosi è stato chiamato a rivalutare un mondo assai intricato cercando di far luce sulle modalità dell’istruzione indicandone prospettive e letture disparate. Le modalità di apprendimento hanno posto l’attenzione su un sistema assai sofisticato ben presto diffuso su un territorio internazionale, l’ordito messo a punto nelle fucine dei conservatori napoletani si rivela efficace ed esportabile ma soprattutto è in grado di soddisfare la bulimica richiesta musicale europea. Se le ‘regole’ assurgono quale grande elemento di osservazione e analisi, in quel successo di intenti ormai riconosciuto universalmente e partito dalle pionieristiche indagini di uno sparuto numero di studiosi temerari quanto tenaci, il mondo che le produce non mostra meno interesse.

Este plan de marketing se ha elaborado con el objetivo de lanzar al mercado con éxito una empresa de nueva creación perteneciente a la industria textil, produciendo y comercializando accesorios sostenibles elaborados con tejido vaquero reciclado. Apoyado en el análisis de situación tanto interno como externo, se ha desarrollado la idea de negocio y las estrategias a seguir. A su vez, se han planteado tres objetivos a cumplir en un horizonte temporal de dos años. Para ello, se ha ideado un programa de acciones de marketing, un plan financiero, un cronograma de acciones para su cumplimiento y se ha especificado cuales son los indicadores que estudiar para su mejor control. Con todo ello, se ha se ha tratado de equilibrar acciones de marketing estratégico con marketing operativo.

The article presents the results of a research that analyzes the construction of knowledge in higher education through practices in institutions and social organizations of social work in Spanish universities. Regarding the method, the universities where the degree is taught (37) are identified, all the subjects related to the “practices” (85) are analyzed through the teaching guides and, finally, the universe of the specific powers attributed to them (572). The results allow categorizing 18 specific skills, 10 transversal skills, 14 relevant professional skills and 6 areas of professional performance. The results of the content analysis show that the acquisition of abilities, skills and abilities through external internships allow the understanding of the methodological application at the different levels of professional intervention and professional fields. Likewise, it should be noted that the practices in institutions and social organizations favor the applied understanding of ethical principles and strategies for resolving ethical dilemmas. Therefore, it is concluded that internships in institutions and social entities facilitate the acquisition of professional skills and abilities in the diversity of development fields, El artículo presenta los resultados de una investigación que analiza la construcción del conocimiento en educación superior a través de las prácticas en instituciones y organizaciones sociales de trabajo social en las universidades españolas. En cuanto al método, se identifican las universidades donde se imparte la titulación (37), se analizan la totalidad de las asignaturas relacionadas con las “prácticas” (85) a través de las guías docentes y, por último, se analiza el universo de las competencias específicas atribuidas a las mismas (572). Los resultados permiten categorizar 18 competencias específicas, 10 competencias transversales, 14 habilidades profesionales relevantes y 6 áreas de desempeño profesional. Los resultados del análisis de contenido, evidencian que la adquisición de capacidades, habilidades y destrezas a través de las prácticas externas permiten la comprensión de la aplicación metodológica en los diferentes niveles de intervención profesional y ámbitos profesionales. Así mismo, destacar que las prácticas en instituciones y organizaciones sociales favorecen la comprensión aplicada de principios deontológicos y estrategias de resolución de dilemas éticos. Por consiguiente, se concluye que las prácticas en instituciones y entidades sociales facilitan la adquisición de competencias y habilidades profesionales en la diversidad de los ámbitos de desarrollo.

Abscisic Acid (ABA) is a phytohormone that is crucial for regulating the stress response pathway in plants. Accumulation of ABA can be triggered by many types of environmental stress, and buildup of ABA can cause changes in plant germination, the elongation and prioritization of primary and lateral root growth, and more. Though we know ABA is an extremely important hormone for plant stress response, we know little about the transcription factors involved in the ABA regulatory pathway. In this thesis we utilize two different sources of genetic diversity in Arabidopsis thaliana to investigate the transcription factors behind the ABA pathway. The first source of genetic diversity comes from artificial micro RNAs (amiRNAs). By screening through a library of seeds containing amiRNAs that target transcription factors, we identified two transcription factors, AIF1 and AIF4, that we believe are involved in the ABA stress response pathway. The second source of genetic diversity comes from naturally occurring ecotypes of Arabidopsis thaliana found in various regions across the globe. By screening through seeds collected from different countries around the world, we found two lineages of Arabidopsis thaliana, one from Bikfaiya, Lebanon, and another from Ciry-le-Noble, France, that demonstrate ABA hypersensitivity compared to Col-0, the current standard for Arabidopsis thaliana research native to Columbia, Missouri, USA. By continuing to analyze these ecotypes of Arabidopsis thaliana, we may be able to discern what naturally occurring genetic variations granted the increased ABA sensitivity we observed during our experimentation.

The article presents the results of a research that analyzes the construction of knowledge in higher education through practices in institutions and social organizations of social work in Spanish universities. Regarding the method, the universities where the degree is taught (37) are identified, all the subjects related to the “practices” (85) are analyzed through the teaching guides and, finally, the universe of the specific powers attributed to them (572). The results allow categorizing 18 specific skills, 10 transversal skills, 14 relevant professional skills and 6 areas of professional performance. The results of the content analysis show that the acquisition of abilities, skills and abilities through external internships allow the understanding of the methodological application at the different levels of professional intervention and professional fields. Likewise, it should be noted that the practices in institutions and social organizations favor the applied understanding of ethical principles and strategies for resolving ethical dilemmas. Therefore, it is concluded that internships in institutions and social entities facilitate the acquisition of professional skills and abilities in the diversity of development fields, El artículo presenta los resultados de una investigación que analiza la construcción del conocimiento en educación superior a través de las prácticas en instituciones y organizaciones sociales de trabajo social en las universidades españolas. En cuanto al método, se identifican las universidades donde se imparte la titulación (37), se analizan la totalidad de las asignaturas relacionadas con las “prácticas” (85) a través de las guías docentes y, por último, se analiza el universo de las competencias específicas atribuidas a las mismas (572). Los resultados permiten categorizar 18 competencias específicas, 10 competencias transversales, 14 habilidades profesionales relevantes y 6 áreas de desempeño profesional. Los resultados del análisis de contenido, evidencian que la adquisición de capacidades, habilidades y destrezas a través de las prácticas externas permiten la comprensión de la aplicación metodológica en los diferentes niveles de intervención profesional y ámbitos profesionales. Así mismo, destacar que las prácticas en instituciones y organizaciones sociales favorecen la comprensión aplicada de principios deontológicos y estrategias de resolución de dilemas éticos. Por consiguiente, se concluye que las prácticas en instituciones y entidades sociales facilitan la adquisición de competencias y habilidades profesionales en la diversidad de los ámbitos de desarrollo.

Questo volume è testimone dell’interesse sviluppatosi negli anni, a cavaliere del secondo e terzo millennio, per il fenomeno della formazione musicale nel corso dei secoli. La ri-fondazione della materia d’indagine, dopo la fase positivistica, è stata sollecitata da una serie di settori d’indagine che ha facilitato la riapertura di un oggetto abbastanza obliato. La curiosità di entrare nei gangli di quelle officine produttrici di musicisti – compositori, strumentisti, cantanti – ha rinnovato gli studi aperti e permesso di apprendere inedite informazioni. Le sollecitazioni più disparate hanno indotto a rimarcare la necessità di sondare fonti dirette e indirette per ragguagliare sempre più questo interessante argomento. Un nugolo di studiosi è stato chiamato a rivalutare un mondo assai intricato cercando di far luce sulle modalità dell’istruzione indicandone prospettive e letture disparate. Le modalità di apprendimento hanno posto l’attenzione su un sistema assai sofisticato ben presto diffuso su un territorio internazionale, l’ordito messo a punto nelle fucine dei conservatori napoletani si rivela efficace ed esportabile ma soprattutto è in grado di soddisfare la bulimica richiesta musicale europea. Se le ‘regole’ assurgono quale grande elemento di osservazione e analisi, in quel successo di intenti ormai riconosciuto universalmente e partito dalle pionieristiche indagini di uno sparuto numero di studiosi temerari quanto tenaci, il mondo che le produce non mostra meno interesse.

The super-weak model is a U(1) extension of the Standard Model. In addition to a mediator $Z'$, a singlet scalar field $\chi$ is added to deal with the meta-stability of the SM vacuum, and right-handed neutrinos are introduced to account for the non-vanishing neutrino masses. We demonstrate that the lightest right-handed neutrino is a possible dark matter candidate with masses of $\mathcal{O}(10)~\mathrm{MeV}$ via the resonant freeze-out scenario. The dark matter production is explored and the available parameter space is discussed from the point of view of various experiments and beyond SM aspects., Comment: 6 pages, 1 figure; Contribution to International Conference on High Energy Physics, 2022

Plant hormones are signalling compounds that regulate crucial aspects of growth, development and environmental stress responses. Abiotic stresses, such as drought, salinity, heat, cold and flooding, have profound effects on plant growth and survival. Adaptation and tolerance to such stresses require sophisticated sensing, signalling and stress response mechanisms. In this Review, we discuss recent advances in understanding how diverse plant hormones control abiotic stress responses in plants and highlight points of hormonal crosstalk during abiotic stress signalling. Control mechanisms and stress responses mediated by plant hormones including abscisic acid, auxin, brassinosteroids, cytokinins, ethylene and gibberellins are discussed. We discuss new insights into osmotic stress sensing and signalling mechanisms, hormonal control of gene regulation and plant development during stress, hormone-regulated submergence tolerance and stomatal movements. We further explore how innovative imaging approaches are providing insights into single-cell and tissue hormone dynamics. Understanding stress tolerance mechanisms opens new opportunities for agricultural applications.

This article presents a descriptive and longitudinal study that analyzes the evolution of the network of own resources of the protection and re-education system of Galicia during the last four decades and the current overview. The objective of the study is to offer an analysis of the evolution of the centres for minors in Galicia and what is the state of the question today. The methodology used for data collection has been the bibliographic and documentary review, especially using as source the Unique Registry of Entities Providers of Social Services of the Autonomous Community of Galicia. The exploitation of data has a mixed nature, quantitative in its description, and qualitative with respect to its analysis. The results obtained show an expansion of resources in the last 40 years aimed at creating a model of community care with some specialized care centres, but which still does not meet, to date, the requirements of the centres regarding the specific demands for action that have emerged during the last decades after the appearance of new care profiles (unaccompanied foreign children and adolescents, minors denounced by their coexistence nucleus, adolescents with mental health problems, adolescent maternity hospitals, etc.)., Este artigo apresenta um estudo descritivo e longitudinal que analisa a evolução da rede de recursos do sistema de protecção e reeducação na Galiza durante as últimas quatro décadas, bem como a situação actual. A metodologia utilizada para a recolha de dados foi uma revisão bibliográfica e análise documental, especialmente utilizando como fonte o Registo Unificado de Prestadores de Serviços Sociais da Comunidade Autónoma da Galiza. Os resultados obtidos identificam e caracterizam todos os recursos actualmente existentes na Galiza e apontam para uma expansão de recursos nos últimos 40 anos no sentido da criação de um modelo de cuidados comunitários com alguns centros de cuidados especializados, mas que ainda não responde à exigências específicas de acção que surgiram nas últimas décadas após o aparecimento de novos perfis de cuidados (crianças e adolescentes estrangeiros não acompanhados, menores denunciados pelo seu núcleo familiar, adolescentes com problemas de saúde mental, maternidades de adolescentes, etc.)., Este artículo presenta un estudio de carácter descriptivo y longitudinal en el que se analiza la evolución de la red de recursos propios del sistema de protección y del de reeducación de Galicia durante las últimas cuatro décadas, así como la panorámica actual. La metodología empleada para la recogida de datos ha sido la revisión bibliográfica y el análisis documental, en especial usando como fuente el Registro Único de Entidades Prestadoras de Servicios Sociales de la Comunidad Autónoma de Galicia. Los resultados obtenidos identifican y caracterizan todos los recursos existentes en la actualidad en Galicia y apuntan a una ampliación de recursos en los últimos 40 años tendente a la creación de un modelo de atención comunitaria con algunos centros de atención especializada, pero que aún no se ajusta, a fecha de hoy, a los requerimientos exigidos a los centros respecto de las demandas de actuación específicas surgidas durante las últimas décadas tras la aparición de nuevos perfiles de atención (niños/as y adolescentes extranjeros no acompañados, menores de edad denunciados por su núcleo convivencial, adolescentes con problemas de salud mental, maternidades adolescentes, etc.).

Background Time-resolved 4D cone beam-computed tomography (4D-CBCT) allows a daily assessment of patient anatomy and respiratory motion. However, 4D-CBCTs suffer from imaging artifacts that affect the CT number accuracy and prevent accurate proton dose calculations. Deep learning can be used to correct CT numbers and generate synthetic CTs (sCTs) that can enable CBCT-based proton dose calculations. Purpose In this work, sparse view 4D-CBCTs were converted into 4D-sCT utilizing a deep convolutional neural network (DCNN). 4D-sCTs were evaluated in terms of image quality and dosimetric accuracy to determine if accurate proton dose calculations for adaptive proton therapy workflows of lung cancer patients are feasible. Methods A dataset of 45 thoracic cancer patients was utilized to train and evaluate a DCNN to generate 4D-sCTs, based on sparse view 4D-CBCTs reconstructed from projections acquired with a 3D acquisition protocol. Mean absolute error (MAE) and mean error were used as metrics to evaluate the image quality of single phases and average 4D-sCTs against 4D-CTs acquired on the same day. The dosimetric accuracy was checked globally (gamma analysis) and locally for target volumes and organs-at-risk (OARs) (lung, heart, and esophagus). Furthermore, 4D-sCTs were also compared to 3D-sCTs. To evaluate CT number accuracy, proton radiography simulations in 4D-sCT and 4D-CTs were compared in terms of range errors. The clinical suitability of 4D-sCTs was demonstrated by performing a 4D dose reconstruction using patient specific treatment delivery log files and breathing signals. Results 4D-sCTs resulted in average MAEs of 48.1 +/- 6.5 HU (single phase) and 37.7 +/- 6.2 HU (average). The global dosimetric evaluation showed gamma pass ratios of 92.3% +/- 3.2% (single phase) and 94.4% +/- 2.1% (average). The clinical target volume showed high agreement in D-98 between 4D-CT and 4D-sCT, with differences below 2.4% for all patients. Larger dose differences were observed in me

Quale potrebbe essere una definizione di ‘bambino prodigio’ musicista applicabile agli standard dei secoli XVIII e XIX? Quali potevano essere le aspettative del pubblico nei confronti di un ‘bambino prodigio’ nella prima metà dell’Ottocento? Quali casi specifici riusciamo a seguire nell’arco di un’ideale ‘carriera’? Quali requisiti doveva soddisfare il Wunderkind? Strumentista virtuoso, improvvisatore, compositore? O probabilmente strumentista e compositore? Qual era l’età media dei prodigi musicali nella prima metà dell’Ottocento? Le attività performative dei giovani talenti oggetto del presente studio vengono seguite attraverso alcune testimonianze della stampa periodica prendendo spunto da un articolo attribuibile a Friedrich Rochlitz (Die frühzeitige Talente [Talenti precoci]) pubblicato il 1 dicembre 1813 sull’«Allgemeine musikalische Zeitung» di Lipsia. Rochlitz invita i lettori del periodico a riflettere sul fenomeno — evidentemente già dilagante — dei talenti precoci, prendendo Mozart come modello e parametro di singolare talento lasciato libero di svilupparsi ‘secondo natura’.

Este plan de marketing se ha elaborado con el objetivo de lanzar al mercado con éxito una empresa de nueva creación perteneciente a la industria textil, produciendo y comercializando accesorios sostenibles elaborados con tejido vaquero reciclado. Apoyado en el análisis de situación tanto interno como externo, se ha desarrollado la idea de negocio y las estrategias a seguir. A su vez, se han planteado tres objetivos a cumplir en un horizonte temporal de dos años. Para ello, se ha ideado un programa de acciones de marketing, un plan financiero, un cronograma de acciones para su cumplimiento y se ha especificado cuales son los indicadores que estudiar para su mejor control. Con todo ello, se ha se ha tratado de equilibrar acciones de marketing estratégico con marketing operativo.

The article presents the results of a research that analyzes the construction of knowledge in higher education through practices in institutions and social organizations of social work in Spanish universities. Regarding the method, the universities where the degree is taught (37) are identified, all the subjects related to the “practices” (85) are analyzed through the teaching guides and, finally, the universe of the specific powers attributed to them (572). The results allow categorizing 18 specific skills, 10 transversal skills, 14 relevant professional skills and 6 areas of professional performance. The results of the content analysis show that the acquisition of abilities, skills and abilities through external internships allow the understanding of the methodological application at the different levels of professional intervention and professional fields. Likewise, it should be noted that the practices in institutions and social organizations favor the applied understanding of ethical principles and strategies for resolving ethical dilemmas. Therefore, it is concluded that internships in institutions and social entities facilitate the acquisition of professional skills and abilities in the diversity of development fields, El artículo presenta los resultados de una investigación que analiza la construcción del conocimiento en educación superior a través de las prácticas en instituciones y organizaciones sociales de trabajo social en las universidades españolas. En cuanto al método, se identifican las universidades donde se imparte la titulación (37), se analizan la totalidad de las asignaturas relacionadas con las “prácticas” (85) a través de las guías docentes y, por último, se analiza el universo de las competencias específicas atribuidas a las mismas (572). Los resultados permiten categorizar 18 competencias específicas, 10 competencias transversales, 14 habilidades profesionales relevantes y 6 áreas de desempeño profesional. Los resultados del análisis de contenido, evidencian que la adquisición de capacidades, habilidades y destrezas a través de las prácticas externas permiten la comprensión de la aplicación metodológica en los diferentes niveles de intervención profesional y ámbitos profesionales. Así mismo, destacar que las prácticas en instituciones y organizaciones sociales favorecen la comprensión aplicada de principios deontológicos y estrategias de resolución de dilemas éticos. Por consiguiente, se concluye que las prácticas en instituciones y entidades sociales facilitan la adquisición de competencias y habilidades profesionales en la diversidad de los ámbitos de desarrollo.

This article presents the results of an empirical investigation aimed at finding out the most significant characteristics and needs of the population of siblings of people affected by rare or infrequent diseases. The objective is to analyze the quality of life of these people in relation to the family environment and the health and social resources to which they have access after the onset of the disease. The research method was based on the administration of a previously validated questionnaire to a sample of 66 people, all of them with a sibling affected by a rare or infrequent disease. The dimensions of the study are related to the level of family interaction, the roles played by parents, family resources, support from health, social and school institutions and, finally, the support received by the affected person. The results obtained reflect a general level of dissatisfaction with the services and support provided to the person affected by a rare disease and to the family, in addition to the fact that the profile of the population surveyed is mostly female and young., El artículo presenta los resultados de una investigación empírica orientada a conocer las características y necesidades más significativas de la población de los/as hermanos/as de personas afectadas por enfermedades raras o poco frecuentes. Se trata de analizar la calidad de vida de estas personas con relación al entorno familiar y los recursos sanitarios y sociales a los que tienen acceso tras la aparición de la enfermedad. El método de investigación se ha basado en la administración de un cuestionario previamente validado a una muestra de 66 personas, todas ellas con un/a hermano/a afectado/a por enfermedad rara o poco frecuente. Las dimensiones del estudio se encuentran relacionadas con el nivel de interacción familiar, roles desempeñados por los progenitores, recursos familiares, apoyo de las instituciones sanitarias, sociales y escolares y, por último, el apoyo recibido por la persona afectada. Los resultados obtenidos reflejan un nivel de descontento general en cuanto a los servicios y apoyos prestados a la persona afectada por una enfermedad rara y a la familia, además de generar un perfil de población encuestada mayoritariamente femenino y joven.

Acquisition of chromatin modifications during embryogenesis distinguishes different regions of an initially naïve genome. In many organisms, repetitive DNA is packaged into constitutive heterochromatin that is marked by di/trimethylation of histone H3K9 and the associated protein HP1a. These modifications enforce the unique epigenetic properties of heterochromatin. However, in the early Drosophila melanogaster embryo, the heterochromatin lacks these modifications, which appear only later, when rapid embryonic cell cycles slow down at the midblastula transition (MBT). Here we focus on the initial steps restoring heterochromatic modifications in the embryo. We describe the JabbaTrap, a technique for inactivating maternally provided proteins in embryos. Using the JabbaTrap, we reveal a major requirement for the methyltransferase Eggless/SetDB1 in the establishment of heterochromatin. In contrast, other methyltransferases contribute minimally. Live imaging reveals that endogenous Eggless gradually accumulates on chromatin in interphase but then dissociates in mitosis, and its accumulation must restart in the next cell cycle. Cell cycle slowing as the embryo approaches the MBT permits increasing accumulation and action of Eggless at its targets. Experimental manipulation of interphase duration shows that cell cycle speed regulates Eggless. We propose that developmental slowing of the cell cycle times embryonic heterochromatin formation.

[ESP] Dentro de los denominados perfiles en riesgo de exclusión, nos encontramos con jóvenes extutelados por la administración pública. Este colectivo deja de estar bajo la guarda, en el momento en el que se ven abocados a cumplir la mayoría de edad, y es ahí cuando se encuentran con la obligación de emanciparse, sin disponer de la madurez suficiente, ni el apoyo o los recursos necesarios para ello. En esta etapa, los jóvenes apenas tienen formación, ni experiencia profesional y tras la salida de los centros residenciales, los miedos, la incertidumbre y lo desconocido, en cierto modo, dificulta su tránsito a la vida adulta. Este estudio centrará su investigación en conocer la situación actual de estos jóvenes en la Región de Murcia y las diferencias y similitudes entre los proyectos que intervienen en el proceso de inserción sociolaboral, mediante un estudio cualitativo a través de entrevistas semiestructuradas online. Los resultados nos muestran la falta de recursos disponibles tanto para los profesionales a la hora de intervenir en los programas y proyectos, como para los y las jóvenes que se encuentran en esta situación de vulnerabilidad. La escasez de coordinación entre profesionales y la falta estructuración en cuanto a las áreas de intervención en relación con las necesidades del perfil, manifiesta la importancia de crear proyectos específicos que aporten apoyo real a los extutelados tras su salida y posterior proceso en búsqueda de una vida normalizada. [ENG] Within the so-called profiles at risk of exclusion, we find young people under the care of the public administration. This group ceases to be under the guardianship, at the moment in which they are forced to reach the age of majority, and that is when they find themselves with the obligation to emancipate themselves, without having sufficient maturity, nos the support or the necessary resources to do so. At this stage, young people have hardly any training or professional experience, and after leaving re

[ES] Este trabajo se trata de un proyecto de emprendimiento que tiene como propósito la creación de una empresa a partir de una idea de negocio. El resultado de dicho proyecto, es un producto cuya comercialización hace viable la existencia de la empresa. Más concretamente se busca la creación de una startup. Toda esta idea surgió por una necesidad: los entrenadores personales de España están comenzando a ofrecer sus servicios de forma online y esto les está ocasionando numerosos problemas relacionados con la gestión de clientes. Al ser nuevo, los entrenadores están trabajando de forma muy manual e ineficiente, lo que se traduce en pérdida de tiempo y dinero. Es por ello que apareció la oportunidad de crear un software para la gestión de clientes de entrenadores personales, el cual no solo permita la automatización de ciertas tareas como los pagos y las suscripciones, sino que también se convierta en la única herramienta de trabajo, con el objetivo de que el entrenador pueda llevar más clientes y así generar unos mayores ingresos. Debido a la envergadura del proyecto, este trabajo de fin de grado se centrará principalmente en la fase de ideación, validación de la idea y desarrollo de ciertos experimentos. Para fases posteriores se desarrollará el MVP y se tratará de buscar el encaje producto/mercado., [EN] This job is about an entrepreneurial project whose purpose is to create a company from a business idea. The result of this project is a product whose commercialization makes the existence of the company viable. More specifically, what is sought is the creation of a startup. This whole idea arose out of a need: personal trainers in Spain are beginning to offer their services online and this is causing them numerous problems related to customer management. Being new, the coaches are working in a completely manual and inefficient way, which results in wasted time and money. This is why the opportunity to create a software for the management of personal trainers clients, which not only allows the automation of certain tasks such as payments and subscriptions, but also becomes the only tool used, appeared with the objective that the coach can take more clients and thus generate greater income. Due to the size of the task, this final degree project will focus mainly on the ideation phase, validation of the idea and development of certain experiments. For later phases, the MVP will be developed and an attempt to find the product/market fit will be made.

[ES] Este trabajo se trata de un proyecto de emprendimiento que tiene como propósito la creación de una empresa a partir de una idea de negocio. El resultado de dicho proyecto, es un producto cuya comercialización hace viable la existencia de la empresa. Más concretamente se busca la creación de una startup. Toda esta idea surgió por una necesidad: los entrenadores personales de España están comenzando a ofrecer sus servicios de forma online y esto les está ocasionando numerosos problemas relacionados con la gestión de clientes. Al ser nuevo, los entrenadores están trabajando de forma muy manual e ineficiente, lo que se traduce en pérdida de tiempo y dinero. Es por ello que apareció la oportunidad de crear un software para la gestión de clientes de entrenadores personales, el cual no solo permita la automatización de ciertas tareas como los pagos y las suscripciones, sino que también se convierta en la única herramienta de trabajo, con el objetivo de que el entrenador pueda llevar más clientes y así generar unos mayores ingresos. Debido a la envergadura del proyecto, este trabajo de fin de grado se centrará principalmente en la fase de ideación, validación de la idea y desarrollo de ciertos experimentos. Para fases posteriores se desarrollará el MVP y se tratará de buscar el encaje producto/mercado., [EN] This job is about an entrepreneurial project whose purpose is to create a company from a business idea. The result of this project is a product whose commercialization makes the existence of the company viable. More specifically, what is sought is the creation of a startup. This whole idea arose out of a need: personal trainers in Spain are beginning to offer their services online and this is causing them numerous problems related to customer management. Being new, the coaches are working in a completely manual and inefficient way, which results in wasted time and money. This is why the opportunity to create a software for the management of personal trainers clients, which not only allows the automation of certain tasks such as payments and subscriptions, but also becomes the only tool used, appeared with the objective that the coach can take more clients and thus generate greater income. Due to the size of the task, this final degree project will focus mainly on the ideation phase, validation of the idea and development of certain experiments. For later phases, the MVP will be developed and an attempt to find the product/market fit will be made.

[ES] Este trabajo se trata de un proyecto de emprendimiento que tiene como propósito la creación de una empresa a partir de una idea de negocio. El resultado de dicho proyecto, es un producto cuya comercialización hace viable la existencia de la empresa. Más concretamente se busca la creación de una startup. Toda esta idea surgió por una necesidad: los entrenadores personales de España están comenzando a ofrecer sus servicios de forma online y esto les está ocasionando numerosos problemas relacionados con la gestión de clientes. Al ser nuevo, los entrenadores están trabajando de forma muy manual e ineficiente, lo que se traduce en pérdida de tiempo y dinero. Es por ello que apareció la oportunidad de crear un software para la gestión de clientes de entrenadores personales, el cual no solo permita la automatización de ciertas tareas como los pagos y las suscripciones, sino que también se convierta en la única herramienta de trabajo, con el objetivo de que el entrenador pueda llevar más clientes y así generar unos mayores ingresos. Debido a la envergadura del proyecto, este trabajo de fin de grado se centrará principalmente en la fase de ideación, validación de la idea y desarrollo de ciertos experimentos. Para fases posteriores se desarrollará el MVP y se tratará de buscar el encaje producto/mercado., [EN] This job is about an entrepreneurial project whose purpose is to create a company from a business idea. The result of this project is a product whose commercialization makes the existence of the company viable. More specifically, what is sought is the creation of a startup. This whole idea arose out of a need: personal trainers in Spain are beginning to offer their services online and this is causing them numerous problems related to customer management. Being new, the coaches are working in a completely manual and inefficient way, which results in wasted time and money. This is why the opportunity to create a software for the management of personal trainers clients, which not only allows the automation of certain tasks such as payments and subscriptions, but also becomes the only tool used, appeared with the objective that the coach can take more clients and thus generate greater income. Due to the size of the task, this final degree project will focus mainly on the ideation phase, validation of the idea and development of certain experiments. For later phases, the MVP will be developed and an attempt to find the product/market fit will be made.

This article aims to present a methodology of social intervention with multi-problem individuals and families from community social services in Spain. According to the 2019 Spanish Social Services Report, these cases represent 25.6% of the care, which makes it necessary to have a method from Social Work. Methodology: The research is based on a review and content analysis of theoretical, methodological, normative and procedural documents used in social work. Results: The intervention methodology is presented, based on a screening tool and its basic phases according to Social Case Work. Conclusion: Having a specific intervention methodology reinforces the professionalization of Social Work., Este artículo tiene como objeto presentar una metodología de intervención social con personas y familias multiproblemáticas desde los Servicios Sociales Comunitarios en España. Según el Informe de Servicios Sociales de 2019, estos casos representan el 25,6% de las atenciones, lo que hace necesario contar con un método desde el Trabajo Social. La investigación se fundamenta en una revisión y análisis de contenido de documentos teóricos, metodológicos, normativos y de procedimientos utilizados en Trabajo Social. Entre los principales resultados destacan: Se presenta la metodología de intervención, basada en una herramienta screening y sus fases básicas según el Trabajo Social de Casos. Se concluye que contar con una metodología de intervención específica refuerza la profesionalización del Trabajo Social.